melatonin has been researched along with Stomatitis in 10 studies
Stomatitis: INFLAMMATION of the soft tissues of the MOUTH, such as MUCOSA; PALATE; GINGIVA; and LIP.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glutaryl melatonin exhibited mild anti-candidiasis and anti-inflammatory properties." | 7.96 | Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis. ( Daduang, J; Damrongrungruang, T; Mahakunakorn, P; Panpitakkul, P; Panyatip, P; Priprem, A; Puthongking, P; Sangchart, P; Somudorn, J; Uthaiwat, P, 2020) |
| " Included studies showed a statistically significant improvement in mucositis severity score for all antioxidants except melatonin." | 5.22 | Efficacy of oral and topical antioxidants in the prevention and management of oral mucositis in head and neck cancer patients: a systematic review and meta-analyses. ( Al-Eryani, K; Emperumal, CP; Enciso, R; Karimyan, N; Raza, A; Watters, A, 2022) |
| "Glutaryl melatonin exhibited mild anti-candidiasis and anti-inflammatory properties." | 3.96 | Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis. ( Daduang, J; Damrongrungruang, T; Mahakunakorn, P; Panpitakkul, P; Panyatip, P; Priprem, A; Puthongking, P; Sangchart, P; Somudorn, J; Uthaiwat, P, 2020) |
| "Treatment with melatonin oral gel showed a consistent trend to lower incidence and shorter SOM duration and shorter duration of UOM." | 3.01 | Randomized placebo-controlled phase II trial of high-dose melatonin mucoadhesive oral gel for the prevention and treatment of oral mucositis in patients with head and neck cancer undergoing radiation therapy concurrent with systemic treatment. ( Bosser, R; Cascallar, L; Escames, G; Farré, N; Giralt, J; Gómez-Millán, J; Grima, P; Lanzuela, M; Lozano, A; Marruecos, J; Mesía, R; Morera, R; Planas, I; Rubió, J; Tarragó, C; Valentí, V; Vázquez-Masedo, MG, 2021) |
| "92." | 2.94 | Efficacy of Melatonin in prevention of radiation-induced oral mucositis: A randomized clinical trial. ( Abdelrahman, H; Elsabagh, HH; Elsaka, RO; Mahmoud, SA; Moussa, E, 2020) |
| "Thirty-nine head and neck cancer patients receiving concurrent chemoradiation (5 days/week of radiation plus chemotherapy three or six cycles)." | 2.84 | Beneficial Effects of Adjuvant Melatonin in Minimizing Oral Mucositis Complications in Head and Neck Cancer Patients Receiving Concurrent Chemoradiation. ( Hurst, C; Johns, J; Johns, NP; Khuayjarernpanishk, T; Onseng, K; Priprem, A; Subongkot, S, 2017) |
| " In addition, the effects of different combinations of MLT dosage and duration, administration types and joint measures are worthy of further study." | 2.82 | Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials. ( Bu, X; Chen, H; Fan, R; Li, X; Tan, Y; Wang, T; Yang, S, 2022) |
| "Oral mucositis was induced in ICR mice by 5-FU and randomly assigned to receive daily applications of the topical oral MNG, a fluocinolone acetonide gel, a blank niosome gel, or no treatment for 5 days in comparison with a normal group." | 1.62 | Topical Melatonin Niosome Gel for the Treatment of 5-FU-Induced Oral Mucositis in Mice. ( Boonsiri, P; Chio-Srichan, S; Daduang, J; Lee, YC; Mahakunakorn, P; Priprem, A; Settasatian, C; Uthaiwat, P, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 7 (70.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raza, A | 1 |
| Karimyan, N | 1 |
| Watters, A | 1 |
| Emperumal, CP | 1 |
| Al-Eryani, K | 1 |
| Enciso, R | 1 |
| Fan, R | 1 |
| Bu, X | 1 |
| Yang, S | 1 |
| Tan, Y | 1 |
| Wang, T | 1 |
| Chen, H | 1 |
| Li, X | 1 |
| Tokuyama-Toda, R | 1 |
| Umeki, H | 1 |
| Okubo, M | 1 |
| Terada-Ito, C | 1 |
| Yudo, T | 1 |
| Ide, S | 1 |
| Tadokoro, S | 1 |
| Shimozuma, M | 1 |
| Satomura, K | 1 |
| Elsabagh, HH | 1 |
| Moussa, E | 1 |
| Mahmoud, SA | 1 |
| Elsaka, RO | 1 |
| Abdelrahman, H | 1 |
| Damrongrungruang, T | 1 |
| Panpitakkul, P | 1 |
| Somudorn, J | 1 |
| Sangchart, P | 1 |
| Mahakunakorn, P | 2 |
| Uthaiwat, P | 2 |
| Daduang, J | 2 |
| Panyatip, P | 1 |
| Puthongking, P | 1 |
| Priprem, A | 3 |
| Settasatian, C | 1 |
| Chio-Srichan, S | 1 |
| Lee, YC | 1 |
| Boonsiri, P | 1 |
| Lozano, A | 1 |
| Marruecos, J | 1 |
| Rubió, J | 1 |
| Farré, N | 1 |
| Gómez-Millán, J | 1 |
| Morera, R | 1 |
| Planas, I | 1 |
| Lanzuela, M | 1 |
| Vázquez-Masedo, MG | 1 |
| Cascallar, L | 1 |
| Giralt, J | 1 |
| Escames, G | 3 |
| Valentí, V | 1 |
| Grima, P | 1 |
| Bosser, R | 1 |
| Tarragó, C | 1 |
| Mesía, R | 1 |
| Abdel Moneim, AE | 1 |
| Guerra-Librero, A | 1 |
| Florido, J | 1 |
| Shen, YQ | 1 |
| Fernández-Gil, B | 1 |
| Acuña-Castroviejo, D | 2 |
| Onseng, K | 1 |
| Johns, NP | 1 |
| Khuayjarernpanishk, T | 1 |
| Subongkot, S | 1 |
| Hurst, C | 1 |
| Johns, J | 1 |
| Ortiz, F | 1 |
| Doerrier, C | 1 |
| Dayoub, JC | 1 |
| López, LC | 1 |
| Venegas, C | 1 |
| García, JA | 1 |
| López, A | 1 |
| Volt, H | 1 |
| Luna-Sánchez, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Alpha Lipoic Acid on the Incidence and Severity of Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients[NCT05023863] | Phase 2/Phase 3 | 70 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis[NCT04308161] | Phase 2 | 45 participants (Anticipated) | Interventional | 2019-11-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for melatonin and Stomatitis
| Article | Year |
|---|---|
Efficacy of oral and topical antioxidants in the prevention and management of oral mucositis in head and neck cancer patients: a systematic review and meta-analyses.
Topics: Adult; Antioxidants; Curcumin; Head and Neck Neoplasms; Humans; Melatonin; Mucositis; Propolis; Sily | 2022 |
Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials.
Topics: Adult; Fatigue; Humans; Melatonin; Neoplasms; Pain; Quality of Life; Randomized Controlled Trials as | 2022 |
Oral Mucositis: Melatonin Gel an Effective New Treatment.
Topics: Animals; Antioxidants; Gels; Humans; Melatonin; Stomatitis | 2017 |
3 trials available for melatonin and Stomatitis
| Article | Year |
|---|---|
Efficacy of Melatonin in prevention of radiation-induced oral mucositis: A randomized clinical trial.
Topics: Antioxidants; Head and Neck Neoplasms; Humans; Melatonin; Radiation Injuries; Saliva; Stomatitis | 2020 |
Randomized placebo-controlled phase II trial of high-dose melatonin mucoadhesive oral gel for the prevention and treatment of oral mucositis in patients with head and neck cancer undergoing radiation therapy concurrent with systemic treatment.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antioxidants; Cetuximab | 2021 |
Beneficial Effects of Adjuvant Melatonin in Minimizing Oral Mucositis Complications in Head and Neck Cancer Patients Receiving Concurrent Chemoradiation.
Topics: Antioxidants; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Melatonin; Middle Ag | 2017 |
4 other studies available for melatonin and Stomatitis
| Article | Year |
|---|---|
The Preventive Effect of Melatonin on Radiation-Induced Oral Mucositis.
Topics: Animals; Apoptosis; Head; Melatonin; Mice; Mouth Mucosa; Stomatitis | 2023 |
Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis.
Topics: Administration, Topical; Anhydrides; Animals; Anti-Inflammatory Agents; Antifungal Agents; Candida a | 2020 |
Topical Melatonin Niosome Gel for the Treatment of 5-FU-Induced Oral Mucositis in Mice.
Topics: Animals; Fluorouracil; Liposomes; Melatonin; Mice; Mice, Inbred ICR; Quality of Life; Stomatitis | 2021 |
Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis.
Topics: Animals; Antioxidants; Carrier Proteins; Inflammasomes; Male; Melatonin; Mitochondria; NLR Family, P | 2015 |