melatonin has been researched along with Spasms, Infantile in 4 studies
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin has also been found to have anticonvulsant and neuroprotective properties by adjusting the circadian rhythm." | 3.11 | Melatonin supplementation for the treatment of infantile spasms: protocol for a randomised placebo-controlled triple-blind trial. ( Chen, J; Feng, W; Liu, M; Shi, X; Sun, Y; Wang, J; Xu, T; Yang, G; Zou, L, 2022) |
| "Melatonin (MT) has been used in clinical treatment for sleep disorders with only minor side effects." | 1.62 | Combined melatonin and adrenocorticotropic hormone treatment attenuates N-methyl-d-aspartate-induced infantile spasms in a rat model by regulating activation of the HPA axis. ( Li, Z; Shi, X; Sun, Y; Wan, L; Wang, J; Yang, G; Zhang, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, Y | 2 |
| Feng, W | 1 |
| Chen, J | 1 |
| Liu, M | 1 |
| Shi, X | 2 |
| Wang, J | 2 |
| Zou, L | 1 |
| Xu, T | 1 |
| Yang, G | 2 |
| Wan, L | 1 |
| Li, Z | 1 |
| Zhang, S | 1 |
| Peled, N | 1 |
| Shorer, Z | 1 |
| Peled, E | 1 |
| Pillar, G | 1 |
| Miyamoto, A | 1 |
| Hara, M | 1 |
| Ito, M | 1 |
| Hayashi, K | 1 |
| Fukuyama, Y | 1 |
2 trials available for melatonin and Spasms, Infantile
| Article | Year |
|---|---|
Melatonin supplementation for the treatment of infantile spasms: protocol for a randomised placebo-controlled triple-blind trial.
Topics: Anticonvulsants; Child, Preschool; Dietary Supplements; Humans; Infant; Melatonin; Neuroprotective A | 2022 |
Melatonin effect on seizures in children with severe neurologic deficit disorders.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Antioxidants; Child; Child, Preschool; Drug Admin | 2001 |
2 other studies available for melatonin and Spasms, Infantile
| Article | Year |
|---|---|
Combined melatonin and adrenocorticotropic hormone treatment attenuates N-methyl-d-aspartate-induced infantile spasms in a rat model by regulating activation of the HPA axis.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Anticonvulsants; Disease Models, Animal; Hum | 2021 |
Serum melatonin kinetics in epileptic children with or without photosensitivity.
Topics: Child; Child, Preschool; Circadian Rhythm; Dark Adaptation; Epilepsy; Female; Humans; Infant; Light; | 1990 |