melatonin has been researched along with Smith-Magenis Syndrome in 13 studies
Smith-Magenis Syndrome: Complex neurobehavioral disorder characterized by distinctive facial features (FACIES), developmental delay and INTELLECTUAL DISABILITY. Behavioral phenotypes include sleep disturbance, maladaptive, self-injurious and attention-seeking behaviors. The sleep disturbance is linked to an abnormal circadian secretion pattern of MELATONIN. The syndrome is associated with de novo deletion or mutation and HAPLOINSUFFICIENCY of the retinoic acid-induced 1 protein on chromosome 17p11.2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Smith-Magenis syndrome (SMS) causes sleep disturbance that is related to an abnormal melatonin profile." | 3.88 | Melanopsin System Dysfunction in Smith-Magenis Syndrome Patients. ( Alves, RC; Barboni, MTS; Bueno, C; Cipolla-Neto, J; do Amaral, FG; Maia, PL; Nagy, BV; Reiter, RJ; Ventura, DF; Vidal, KSM, 2018) |
| "Melatonin secretion is usually increased during the daytime and decreased at night in Smith-Magenis syndrome (SMS) and consequently is not a pertinent marker of the circadian phase of the clock in these cases." | 3.81 | Phase advance of circadian rhythms in Smith-Magenis syndrome: a case study in an adult man. ( Azabou, E; Brun, J; Claustrat, B; Devillard, F; Kocher, L, 2015) |
| "Smith-Magenis syndrome (SMS) is associated with sleep disturbances and disrupted melatonin production." | 3.78 | Alteration of the circadian clock in children with Smith-Magenis syndrome. ( Nevsímalová, S; Nováková, M; Príhodová, I; Sládek, M; Sumová, A, 2012) |
| "Most SMS patients have sleep disorders such as short total sleep time, frequent night waking, short sleep onset, and early morning waking." | 1.62 | [Sleep disturbance associated with Smith-Magenis syndrome]. ( Chen, L; Pan, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, M | 1 |
| Chen, L | 1 |
| Kaplan, KA | 1 |
| Elsea, SH | 1 |
| Potocki, L | 2 |
| Woodford, EC | 1 |
| McLay, L | 1 |
| France, KG | 1 |
| Blampied, NM | 1 |
| Gibbs, R | 1 |
| Swan, CE | 1 |
| Eggleston, M | 1 |
| Barboni, MTS | 1 |
| Bueno, C | 1 |
| Nagy, BV | 1 |
| Maia, PL | 1 |
| Vidal, KSM | 1 |
| Alves, RC | 1 |
| Reiter, RJ | 2 |
| do Amaral, FG | 1 |
| Cipolla-Neto, J | 1 |
| Ventura, DF | 1 |
| Smith, ACM | 1 |
| Morse, RS | 1 |
| Introne, W | 1 |
| Duncan, WC | 1 |
| Poisson, A | 1 |
| Nicolas, A | 1 |
| Bousquet, I | 1 |
| Raverot, V | 1 |
| Gronfier, C | 1 |
| Demily, C | 1 |
| Grigg-Damberger, M | 1 |
| Ralls, F | 1 |
| Kocher, L | 1 |
| Brun, J | 1 |
| Devillard, F | 1 |
| Azabou, E | 1 |
| Claustrat, B | 1 |
| Nijim, Y | 1 |
| Adawi, A | 1 |
| Bisharat, B | 1 |
| Bowirrat, A | 1 |
| Spruyt, K | 1 |
| Braam, W | 1 |
| Smits, M | 1 |
| Curfs, LM | 1 |
| Van Thillo, A | 1 |
| Devriendt, K | 1 |
| Willekens, D | 1 |
| Boone, PM | 1 |
| Glaze, DG | 1 |
| Tan, DX | 1 |
| Lupski, JR | 1 |
| Nováková, M | 1 |
| Nevsímalová, S | 1 |
| Príhodová, I | 1 |
| Sládek, M | 1 |
| Sumová, A | 1 |
4 reviews available for melatonin and Smith-Magenis Syndrome
| Article | Year |
|---|---|
Management of Sleep Disturbances Associated with Smith-Magenis Syndrome.
Topics: Animals; Humans; Melatonin; Mutation; Quality of Life; Sleep; Sleep Wake Disorders; Smith-Magenis Sy | 2020 |
Endogenous melatonin and sleep in individuals with Rare Genetic Neurodevelopmental Disorders (RGND): A systematic review.
Topics: Humans; Melatonin; Neurodevelopmental Disorders; Sleep; Sleep Wake Disorders; Smith-Magenis Syndrome | 2021 |
Smith-Magenis Syndrome: Molecular Basis of a Genetic-Driven Melatonin Circadian Secretion Disorder.
Topics: Animals; Chromosome Mapping; Circadian Rhythm; Disease Susceptibility; Genetic Predisposition to Dis | 2019 |
Treatment strategies for complex behavioral insomnia in children with neurodevelopmental disorders.
Topics: Angelman Syndrome; Central Nervous System Depressants; Child; Child Development Disorders, Pervasive | 2013 |
9 other studies available for melatonin and Smith-Magenis Syndrome
| Article | Year |
|---|---|
[Sleep disturbance associated with Smith-Magenis syndrome].
Topics: Animals; Circadian Rhythm; Humans; Melatonin; Mice; Sleep; Sleep Wake Disorders; Smith-Magenis Syndr | 2021 |
Melanopsin System Dysfunction in Smith-Magenis Syndrome Patients.
Topics: Adolescent; Adult; Child; Female; Humans; Male; Melatonin; Pupil; Reflex, Pupillary; Retinal Disease | 2018 |
Twenty-four-hour motor activity and body temperature patterns suggest altered central circadian timekeeping in Smith-Magenis syndrome, a neurodevelopmental disorder.
Topics: Adolescent; Adult; Body Temperature; Child; Chromosomes, Human, Pair 17; Circadian Clocks; Circadian | 2019 |
Phase advance of circadian rhythms in Smith-Magenis syndrome: a case study in an adult man.
Topics: Actigraphy; Adult; Body Temperature; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; Slee | 2015 |
First Case Report of Smith-Magenis Syndrome (SMS) Among the Arab Community in Nazareth: View and Overview.
Topics: Acebutolol; Adrenergic beta-1 Receptor Antagonists; Antioxidants; Arabs; Chromosome Deletion; Drug C | 2016 |
Sleep Complaints and the 24-h Melatonin Level in Individuals with Smith-Magenis Syndrome: Assessment for Effective Intervention.
Topics: Adult; Age Factors; Child; Child, Preschool; Circadian Rhythm; Eating; Female; Humans; Male; Melaton | 2016 |
[Sleep disturbances in Smith-Magenis syndrome: treatment with melatonin and beta-adrenergic antagonists].
Topics: Adrenergic beta-Antagonists; Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair 17; Chr | 2010 |
Abnormal circadian rhythm of melatonin in Smith-Magenis syndrome patients with RAI1 point mutations.
Topics: Adult; Child; Circadian Rhythm; Female; Genetic Association Studies; Humans; Male; Melatonin; Point | 2011 |
Alteration of the circadian clock in children with Smith-Magenis syndrome.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Circadian Clocks; Circadian Rhythm; CLOCK | 2012 |