Page last updated: 2024-10-19

melatonin and Sleepiness

melatonin has been researched along with Sleepiness in 22 studies

Sleepiness: Compelling urge to sleep.

Research Excerpts

ExcerptRelevanceReference
"Presleep exposure to short-wavelength light suppresses melatonin and decreases sleepiness with activating effects extending to sleep."9.51Melatonin suppression does not automatically alter sleepiness, vigilance, sensory processing, or sleep. ( Bekinschtein, TA; Blume, C; Cajochen, C; Meyer, MP; Niedernhuber, M; Slawik, HC; Spitschan, M, 2022)
"A physiologically based model of arousal dynamics is improved to incorporate the effects of the light spectrum on circadian phase resetting, melatonin suppression, and subjective sleepiness."7.96Modeling melanopsin-mediated effects of light on circadian phase, melatonin suppression, and subjective sleepiness. ( Lockley, SW; McCloskey, S; Postnova, S; Robinson, PA; Tekieh, T; Zobaer, MS, 2020)
" Pittsburgh Sleep Quality Index (PSQI), Positive and Negative Affect Schedule (PANAS), Visual Function Questionnaire (VFQ), Epworth Sleepiness Scale (ESS) and salivary melatonin and cortisol levels were assessed for both groups before and 3 months after the intervention."5.69Investigating the effects of a blue-blocking software on the daily rhythm of sleep, melatonin, cortisol, positive and negative emotions. ( Dabaghi, P; Khosravifard, K; Makateb, A; Rashidinia, A, 2023)
"To observe the acupoint compatibility effect of Shenmen (HT7) and Sanyinjiao (SP6) in improving daytime fatigue and sleepiness of insomnia, and its mechanism in regulating hypothalamic-pituitary-adrenal (HPA) axis and suprachiasmatic nucleus-pineal gland-melatonin (SCN-PG-MT) system."5.51[Acupoint compatibility effect and mechanism of Shenmen (HT7) and Sanyinjiao (SP6) in improving daytime fatigue and sleepiness of insomnia]. ( Du, L; Li, ZW; Song, XJ; Wu, P; Zhu, YH, 2022)
"Subjective sleepiness in children exposed to 6200 K light was significantly lower than that in children exposed to 3000 K light."5.48Melatonin suppression and sleepiness in children exposed to blue-enriched white LED lighting at night. ( Eto, T; Higuchi, S; Ikeda, Y; Lee, SI; Matsumori, K; Nishimura, K; Nishimura, Y, 2018)
" The classical markers of the circadian system (melatonin and cortisol), as well as the subjective perception of sleepiness, mood, and visual comfort, were compared."3.91Awakening effects of blue-enriched morning light exposure on university students' physiological and subjective responses. ( Choi, K; Chung, HJ; Kim, T; Shin, C; Suk, HJ, 2019)
" Dietary intake, satiety, sleepiness, glycemic response, salivary cortisol and melatonin were also assessed."3.91Effect of the intake of high or low glycemic index high carbohydrate-meals on athletes' sleep quality in pre-game nights. ( Daniel, NVS; Estadella, D; Garcia, MC; Juzwiak, CR; Padovani, RC; Zimberg, IZ, 2019)
" Healthy human participants (n = 11) were exposed to the VDU from 18:00 to 23:00 hours at high- or low-melanopic setting in a randomized cross-over design and measured salivary melatonin and self-reported sleepiness at 30-minute intervals."3.88Exploiting metamerism to regulate the impact of a visual display on alertness and melatonin suppression independent of visual appearance. ( Allen, AE; Cajochen, C; Hazelhoff, EM; Lucas, RJ; Martial, FP, 2018)
" Adverse events were registered for each route of administration."3.01Pharmacokinetics and Safety of Intravenous, Intravesical, Rectal, Transdermal, and Vaginal Melatonin in Healthy Female Volunteers: A Cross-Over Study. ( Alder, R; Andersen, LPK; Jessen, ML; Rosenberg, J; Tolstrup, A; Zetner, D, 2021)
"Subjective sleepiness was measured daily (heavy eyelids, reduced performance) and every second hour while awake (Karolinska Sleepiness Scale, KSS)."3.01The effects of bright light treatment on subjective and objective sleepiness during three consecutive night shifts among hospital nurses - a counter-balanced placebo-controlled crossover study. ( Bjorvatn, B; Blytt, KM; Pallesen, S; Thun, E; Waage, S, 2021)
"Subjective and objective sleepiness and sleep-related and hazardous driving events significantly increased following night shift compared with preshift."1.51Sleepiness and driving events in shift workers: the impact of circadian and homeostatic factors. ( Anderson, C; Collins, A; Ganesan, S; Howard, ME; Lockley, SW; Magee, M; Mulhall, MD; Rajaratnam, SMW; Sletten, TL; Stone, JE, 2019)
"Objective sleepiness was significantly reduced, depending on melanopic irradiance, at low illuminance (100 lux) and showed fewer differences at higher illuminance."1.51Living in Biological Darkness: Objective Sleepiness and the Pupillary Light Responses Are Affected by Different Metameric Lighting Conditions during Daytime. ( Bes, F; de Zeeuw, J; Hädel, S; Kunz, D; Münch, M; Nowozin, C; Papakonstantinou, A; Stotz, S; Zaleska, M, 2019)
"Subjective sleepiness, melatonin and cortisol were assessed hourly."1.46Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness. ( Cajochen, C; Gabel, V; Garbazza, C; Kolodyazhniy, V; Maire, M; Reichert, CF; Schlangen, LJM; Schmidt, C; Viola, AU, 2017)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (36.36)24.3611
2020's14 (63.64)2.80

Authors

AuthorsStudies
Joyce, DS1
Spitschan, M2
Zeitzer, JM1
Song, XJ1
Zhu, YH1
Wu, P1
Du, L1
Li, ZW1
Blume, C1
Niedernhuber, M1
Slawik, HC1
Meyer, MP1
Bekinschtein, TA1
Cajochen, C4
Meth, EMS1
Brandão, LEM1
van Egmond, LT1
Xue, P1
Grip, A1
Wu, J1
Adan, A1
Andersson, F1
Pacheco, AP1
Uvnäs-Moberg, K1
Cedernaes, J1
Benedict, C1
Kunorozva, L1
Rae, DE1
Roden, LC1
Youngstedt, SD3
Elliott, J3
Patel, S3
Zi-Ching Mak, N3
Raiewski, E3
Malek, E3
Strong, M3
Mun, CJ3
Peters, T3
Madlol, R3
Tasevska, N3
Rasoul, M3
Nguyen, C3
Vargas Negrete, KM3
Adaralegbe, AO3
Sudalaimuthu, S3
Granholm, D3
Finch, A3
Eksambe, A3
Malready, A3
Parthasarathy, S3
Makateb, A1
Rashidinia, A1
Khosravifard, K1
Dabaghi, P1
Schöllhorn, I1
Deuring, G1
Stefani, O1
Strumberger, MA1
Rosburg, T1
Lemoine, P1
Pross, A1
Wingert, B1
Mager, R1
Didikoglu, A1
Mohammadian, N1
Johnson, S1
van Tongeren, M1
Wright, P1
Casson, AJ1
Brown, TM1
Lucas, RJ2
Tekieh, T1
Lockley, SW2
Robinson, PA1
McCloskey, S1
Zobaer, MS1
Postnova, S1
Zetner, D1
Andersen, LPK1
Alder, R1
Jessen, ML1
Tolstrup, A1
Rosenberg, J1
Bani Issa, W1
Abdul Rahman, H1
Albluwi, N1
Samsudin, ABR1
Abraham, S1
Saqan, R1
Naing, L1
Bjorvatn, B1
Pallesen, S1
Waage, S1
Thun, E1
Blytt, KM1
Danilenko, KV1
Kobelev, E1
Zhanaeva, SY1
Aftanas, LI1
Gabel, V1
Reichert, CF1
Maire, M1
Schmidt, C1
Schlangen, LJM1
Kolodyazhniy, V1
Garbazza, C1
Viola, AU1
Short, MA1
Weber, N1
Reynolds, C1
Coussens, S1
Carskadon, MA1
Allen, AE1
Hazelhoff, EM1
Martial, FP1
Lee, SI1
Matsumori, K1
Nishimura, K1
Nishimura, Y1
Ikeda, Y1
Eto, T1
Higuchi, S1
Choi, K1
Shin, C1
Kim, T1
Chung, HJ1
Suk, HJ1
Mulhall, MD1
Sletten, TL1
Magee, M1
Stone, JE1
Ganesan, S1
Collins, A1
Anderson, C1
Howard, ME1
Rajaratnam, SMW1
Daniel, NVS1
Zimberg, IZ1
Estadella, D1
Garcia, MC1
Padovani, RC1
Juzwiak, CR1
de Zeeuw, J1
Papakonstantinou, A1
Nowozin, C1
Stotz, S1
Zaleska, M1
Hädel, S1
Bes, F1
Münch, M1
Kunz, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bright Light as a Countermeasure for Circadian Desynchrony[NCT01119365]300 participants (Anticipated)Interventional2011-07-31Recruiting
Treating Sleep Disruption in Teens With Millisecond Light Exposure During Sleep[NCT01406691]Phase 420 participants (Anticipated)Interventional2013-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for melatonin and Sleepiness

ArticleYear
[Acupoint compatibility effect and mechanism of Shenmen (HT7) and Sanyinjiao (SP6) in improving daytime fatigue and sleepiness of insomnia].
    Zhen ci yan jiu = Acupuncture research, 2022, Jul-25, Volume: 47, Issue:7

    Topics: Acupuncture Points; Adrenocorticotropic Hormone; Fatigue; Humans; Melatonin; Sleep Initiation and Ma

2022
Melatonin suppression does not automatically alter sleepiness, vigilance, sensory processing, or sleep.
    Sleep, 2022, 11-09, Volume: 45, Issue:11

    Topics: Circadian Rhythm; Female; Humans; Light; Melatonin; Perception; Sleep; Sleepiness; Wakefulness

2022
Circadian acclimatization of performance, sleep, and 6-sulfatoxymelatonin using multiple phase shifting stimuli.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Acclimatization; Adult; Humans; Jet Lag Syndrome; Melatonin; Sleep; Sleepiness

2022
Circadian acclimatization of performance, sleep, and 6-sulfatoxymelatonin using multiple phase shifting stimuli.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Acclimatization; Adult; Humans; Jet Lag Syndrome; Melatonin; Sleep; Sleepiness

2022
Circadian acclimatization of performance, sleep, and 6-sulfatoxymelatonin using multiple phase shifting stimuli.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Acclimatization; Adult; Humans; Jet Lag Syndrome; Melatonin; Sleep; Sleepiness

2022
Circadian acclimatization of performance, sleep, and 6-sulfatoxymelatonin using multiple phase shifting stimuli.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Acclimatization; Adult; Humans; Jet Lag Syndrome; Melatonin; Sleep; Sleepiness

2022
Investigating the effects of a blue-blocking software on the daily rhythm of sleep, melatonin, cortisol, positive and negative emotions.
    Chronobiology international, 2023, 07-03, Volume: 40, Issue:7

    Topics: Circadian Rhythm; Emotions; Humans; Hydrocortisone; Melatonin; Sleep; Sleepiness; Software

2023
Pharmacokinetics and Safety of Intravenous, Intravesical, Rectal, Transdermal, and Vaginal Melatonin in Healthy Female Volunteers: A Cross-Over Study.
    Pharmacology, 2021, Volume: 106, Issue:3-4

    Topics: Administration, Cutaneous; Administration, Intravaginal; Administration, Intravenous; Administration

2021
The effects of bright light treatment on subjective and objective sleepiness during three consecutive night shifts among hospital nurses - a counter-balanced placebo-controlled crossover study.
    Scandinavian journal of work, environment & health, 2021, 03-01, Volume: 47, Issue:2

    Topics: Circadian Rhythm; Cross-Over Studies; Hospitals; Humans; Melatonin; Sleep; Sleepiness; Wakefulness;

2021

Other Studies

16 other studies available for melatonin and Sleepiness

ArticleYear
Duration invariance and intensity dependence of the human circadian system phase shifting response to brief light flashes.
    Proceedings. Biological sciences, 2022, 03-09, Volume: 289, Issue:1970

    Topics: Circadian Rhythm; Humans; Melatonin; Retinal Cone Photoreceptor Cells; Retinal Ganglion Cells; Rod O

2022
Duration invariance and intensity dependence of the human circadian system phase shifting response to brief light flashes.
    Proceedings. Biological sciences, 2022, 03-09, Volume: 289, Issue:1970

    Topics: Circadian Rhythm; Humans; Melatonin; Retinal Cone Photoreceptor Cells; Retinal Ganglion Cells; Rod O

2022
Duration invariance and intensity dependence of the human circadian system phase shifting response to brief light flashes.
    Proceedings. Biological sciences, 2022, 03-09, Volume: 289, Issue:1970

    Topics: Circadian Rhythm; Humans; Melatonin; Retinal Cone Photoreceptor Cells; Retinal Ganglion Cells; Rod O

2022
Duration invariance and intensity dependence of the human circadian system phase shifting response to brief light flashes.
    Proceedings. Biological sciences, 2022, 03-09, Volume: 289, Issue:1970

    Topics: Circadian Rhythm; Humans; Melatonin; Retinal Cone Photoreceptor Cells; Retinal Ganglion Cells; Rod O

2022
A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults.
    Journal of sleep research, 2023, Volume: 32, Issue:2

    Topics: Adult; Body Weight; Circadian Rhythm; Cross-Over Studies; Female; Humans; Male; Melatonin; Oxytocin;

2023
Dim light melatonin onset following simulated eastward travel is earlier in young males genotyped as
    Chronobiology international, 2022, Volume: 39, Issue:12

    Topics: Circadian Rhythm; Genotype; Humans; Light; Male; Melatonin; Period Circadian Proteins; Sleep; Sleepi

2022
Effects of nature-adapted lighting solutions ("Virtual Sky") on subjective and objective correlates of sleepiness, well-being, visual and cognitive performance at the workplace.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Circadian Rhythm; Cognition; Cross-Over Studies; Humans; Hydrocortisone; Light; Lighting; Male; Mela

2023
Associations between light exposure and sleep timing and sleepiness while awake in a sample of UK adults in everyday life.
    Proceedings of the National Academy of Sciences of the United States of America, 2023, 10-17, Volume: 120, Issue:42

    Topics: Adult; Circadian Rhythm; Humans; Melatonin; Sleep; Sleepiness; United Kingdom; Wakefulness

2023
Modeling melanopsin-mediated effects of light on circadian phase, melatonin suppression, and subjective sleepiness.
    Journal of pineal research, 2020, Volume: 69, Issue:3

    Topics: Circadian Rhythm; Humans; Melatonin; Models, Neurological; Rod Opsins; Sleep; Sleepiness; Wakefulnes

2020
Morning and evening salivary melatonin, sleepiness and chronotype: A comparative study of nurses on fixed day and rotating night shifts.
    Journal of advanced nursing, 2020, Volume: 76, Issue:12

    Topics: Circadian Rhythm; Cross-Sectional Studies; Female; Humans; Melatonin; Nurses; Sleep; Sleepiness; Wor

2020
Winter-summer difference in post-awakening salivary α-amylase and sleepiness depending on sleep and melatonin.
    Physiology & behavior, 2021, 10-15, Volume: 240

    Topics: Circadian Rhythm; Humans; Melatonin; Salivary alpha-Amylases; Seasons; Sleep; Sleepiness

2021
Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness.
    Scientific reports, 2017, 08-08, Volume: 7, Issue:1

    Topics: Adult; Age Factors; Aged; Attention; Circadian Rhythm; Cross-Over Studies; Female; Humans; Hydrocort

2017
Estimating adolescent sleep need using dose-response modeling.
    Sleep, 2018, 04-01, Volume: 41, Issue:4

    Topics: Adolescent; Attention; Circadian Rhythm; Female; Homeostasis; Humans; Male; Melatonin; Sleep; Sleep

2018
Exploiting metamerism to regulate the impact of a visual display on alertness and melatonin suppression independent of visual appearance.
    Sleep, 2018, 08-01, Volume: 41, Issue:8

    Topics: Adult; Attention; Circadian Rhythm; Color; Cross-Over Studies; Humans; Light; Male; Melatonin; Saliv

2018
Melatonin suppression and sleepiness in children exposed to blue-enriched white LED lighting at night.
    Physiological reports, 2018, Volume: 6, Issue:24

    Topics: Adult; Age Factors; Child; Circadian Rhythm; Female; Humans; Light; Lighting; Male; Melatonin; Middl

2018
Awakening effects of blue-enriched morning light exposure on university students' physiological and subjective responses.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Affect; Circadian Rhythm; Female; Humans; Hydrocortisone; Light; Lighting; Male; Melatonin; R

2019
Sleepiness and driving events in shift workers: the impact of circadian and homeostatic factors.
    Sleep, 2019, 06-11, Volume: 42, Issue:6

    Topics: Actigraphy; Adult; Automobile Driving; Circadian Rhythm; Cognition; Female; Homeostasis; Humans; Mal

2019
Effect of the intake of high or low glycemic index high carbohydrate-meals on athletes' sleep quality in pre-game nights.
    Anais da Academia Brasileira de Ciencias, 2019, Volume: 91, Issue:1

    Topics: Adolescent; Athletes; Athletic Performance; Cross-Sectional Studies; Dietary Carbohydrates; Energy I

2019
Living in Biological Darkness: Objective Sleepiness and the Pupillary Light Responses Are Affected by Different Metameric Lighting Conditions during Daytime.
    Journal of biological rhythms, 2019, Volume: 34, Issue:4

    Topics: Adult; Circadian Rhythm; Darkness; Electroencephalography; Female; Humans; Light; Male; Melatonin; P

2019