melatonin has been researched along with Shock, Septic in 15 studies
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to evaluate the nocturnal melatonin concentration and total 24-hr excretion of 6-sulfatoxymelatoninsulfate, melatonin's major urinary metabolite, in children with sepsis in the pediatric intensive care unit." | 7.78 | Melatonin status in pediatric intensive care patients with sepsis. ( Bagci, S; Bartmann, P; Horoz, ÖÖ; Müller, A; Reinsberg, J; Yildizdas, D, 2012) |
| "Melatonin is a hormone that regulates sleep and wakefulness, and it is associated with a reduced risk of death in patients with sepsis." | 6.82 | Melatonin: A window into the organ-protective effects of sepsis. ( Huang, X; Lan, Y; Lei, Y; Li, J; Liu, R; Luo, X; Yang, F; Zeng, F, 2022) |
| "The pathogenesis of multiple organ dysfunction syndrome (MODS) in septic shock is complicated and not fully understood." | 5.35 | Therapeutic effects of melatonin on peritonitis-induced septic shock with multiple organ dysfunction syndrome in rats. ( Chen, SJ; Chen, TH; Tsao, CM; Tsou, MY; Wu, CC; Wu, JY, 2008) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| " The aim of this study was to evaluate the nocturnal melatonin concentration and total 24-hr excretion of 6-sulfatoxymelatoninsulfate, melatonin's major urinary metabolite, in children with sepsis in the pediatric intensive care unit." | 3.78 | Melatonin status in pediatric intensive care patients with sepsis. ( Bagci, S; Bartmann, P; Horoz, ÖÖ; Müller, A; Reinsberg, J; Yildizdas, D, 2012) |
| "The melatonin-treated patients had more ventilator-free days than placebo-treated patients over the 28-day (16." | 3.11 | A pilot study on the melatonin treatment in patients with early septic shock: results of a single-center randomized controlled trial. ( Abdoli, E; Mehrpooya, M; Mohammadi, Y; Shokoohmand, F; Taher, A, 2022) |
| "Melatonin is a hormone that regulates sleep and wakefulness, and it is associated with a reduced risk of death in patients with sepsis." | 2.82 | Melatonin: A window into the organ-protective effects of sepsis. ( Huang, X; Lan, Y; Lei, Y; Li, J; Liu, R; Luo, X; Yang, F; Zeng, F, 2022) |
| "Melatonin plays an important physiologic role in sleep and circadian rhythm regulation, immunoregulation, antioxidant and mitochondrial-protective functions, reproductive control, and regulation of mood." | 2.46 | Melatonin in septic shock: some recent concepts. ( Cardinali, DP; Kato, H; Pandi-Perumal, SR; Spence, DW; Srinivasan, V, 2010) |
| "Melatonin has well documented protective effects against the symptoms of severe sepsis/shock in both animals and in humans; its use for this condition significantly improves survival." | 2.43 | Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence. ( Acuña-Castroviejo, D; Escames, G; León, J; López, LC; Maldonado, MD; Reiter, RJ; Sánchez-Hidalgo, M; Tan, DX, 2006) |
| "The pathogenesis of multiple organ dysfunction syndrome (MODS) in septic shock is complicated and not fully understood." | 1.35 | Therapeutic effects of melatonin on peritonitis-induced septic shock with multiple organ dysfunction syndrome in rats. ( Chen, SJ; Chen, TH; Tsao, CM; Tsou, MY; Wu, CC; Wu, JY, 2008) |
| "The melatonin effect was mediated by modulating the release of pro-/anti-inflammatory cytokine levels, protection from oxidative damage and counteracting apoptotic cell death." | 1.33 | Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and anti-apoptotic effects. ( Calvo, JR; Carrillo-Vico, A; Fernández-Santos, JM; Guerrero, JM; Lardone, PJ; Martín-Lacave, I; Naji, L, 2005) |
| "LPS-induced septic shock is characterized by hypotension and vascular hyporeactivity to contracting agents." | 1.32 | Melatonin prevents lipopolysaccharide-induced hyporeactivity in rat. ( Autore, G; Cuzzocrea, S; d'Emmanuele di Villa Bianca, R; Di Paola, R; Marzocco, S; Pinto, A; Sorrentino, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taher, A | 1 |
| Shokoohmand, F | 1 |
| Abdoli, E | 1 |
| Mohammadi, Y | 1 |
| Mehrpooya, M | 1 |
| Liu, R | 1 |
| Luo, X | 1 |
| Li, J | 1 |
| Lei, Y | 1 |
| Zeng, F | 1 |
| Huang, X | 1 |
| Lan, Y | 1 |
| Yang, F | 1 |
| da Silva, FP | 1 |
| Machado, MC | 1 |
| Sallet, PC | 1 |
| Zampieri, FG | 1 |
| Goulart, AC | 1 |
| Torggler Filho, F | 1 |
| Barbeiro, HV | 1 |
| Velasco, IT | 1 |
| da Cruz Neto, LM | 1 |
| de Souza, HP | 1 |
| Shim, DW | 1 |
| Shin, HJ | 1 |
| Han, JW | 1 |
| Ji, YE | 1 |
| Jang, CH | 1 |
| Koppula, S | 1 |
| Kang, TB | 1 |
| Lee, KH | 1 |
| Bitzer-Quintero, OK | 1 |
| Dávalos-Marín, AJ | 1 |
| Ortiz, GG | 1 |
| Meza, AR | 1 |
| Torres-Mendoza, BM | 1 |
| Robles, RG | 1 |
| Huerta, VC | 1 |
| Beas-Zárate, C | 1 |
| Srinivasan, V | 1 |
| Pandi-Perumal, SR | 1 |
| Spence, DW | 1 |
| Kato, H | 1 |
| Cardinali, DP | 1 |
| Bagci, S | 1 |
| Horoz, ÖÖ | 1 |
| Yildizdas, D | 1 |
| Reinsberg, J | 1 |
| Bartmann, P | 1 |
| Müller, A | 1 |
| d'Emmanuele di Villa Bianca, R | 1 |
| Marzocco, S | 1 |
| Di Paola, R | 1 |
| Autore, G | 1 |
| Pinto, A | 1 |
| Cuzzocrea, S | 1 |
| Sorrentino, R | 1 |
| Carrillo-Vico, A | 1 |
| Lardone, PJ | 1 |
| Naji, L | 1 |
| Fernández-Santos, JM | 1 |
| Martín-Lacave, I | 1 |
| Guerrero, JM | 1 |
| Calvo, JR | 1 |
| Escames, G | 1 |
| Acuña-Castroviejo, D | 1 |
| López, LC | 1 |
| Tan, DX | 1 |
| Maldonado, MD | 1 |
| Sánchez-Hidalgo, M | 1 |
| León, J | 1 |
| Reiter, RJ | 1 |
| Wu, JY | 1 |
| Tsou, MY | 1 |
| Chen, TH | 1 |
| Chen, SJ | 1 |
| Tsao, CM | 1 |
| Wu, CC | 2 |
| Maestroni, GJ | 1 |
| Baykal, A | 1 |
| Iskit, AB | 1 |
| Hamaloglu, E | 1 |
| Guc, MO | 1 |
| Hascelik, G | 1 |
| Sayek, I | 1 |
| Chiao, CW | 1 |
| Hsiao, G | 1 |
| Chen, A | 1 |
| Yen, MH | 1 |
4 reviews available for melatonin and Shock, Septic
| Article | Year |
|---|---|
Melatonin: A window into the organ-protective effects of sepsis.
Topics: Humans; Melatonin; Sepsis; Shock, Septic | 2022 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Melatonin in septic shock: some recent concepts.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Disease Models, Animal; Humans; Inflammation; Melatoni | 2010 |
Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Clinical Trials as Topic; Cytokines; Glut | 2006 |
2 trials available for melatonin and Shock, Septic
| Article | Year |
|---|---|
A pilot study on the melatonin treatment in patients with early septic shock: results of a single-center randomized controlled trial.
Topics: Double-Blind Method; Humans; Melatonin; Organ Dysfunction Scores; Pilot Projects; Respiration, Artif | 2022 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
10 other studies available for melatonin and Shock, Septic
| Article | Year |
|---|---|
Neuropeptide downregulation in sepsis.
Topics: alpha-MSH; Cohort Studies; Down-Regulation; Humans; Hydrocortisone; Inflammation; Melatonin; Neurope | 2014 |
A novel synthetic derivative of melatonin, 5-hydroxy-2'-isobutyl-streptochlorin (HIS), inhibits inflammatory responses via regulation of TRIF-dependent signaling and inflammasome activation.
Topics: Acute Lung Injury; Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents; Cell Li | 2015 |
Antioxidant activity of tryptophan in rats under experimental endotoxic shock.
Topics: Animals; Animals, Suckling; Antioxidants; Cytokines; Dietary Supplements; Disease Models, Animal; Fe | 2010 |
Melatonin status in pediatric intensive care patients with sepsis.
Topics: Biomarkers; Case-Control Studies; Child; Child, Preschool; Circadian Rhythm; Female; Hospital Mortal | 2012 |
Melatonin prevents lipopolysaccharide-induced hyporeactivity in rat.
Topics: Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Lipopolysaccharides; Male; Melatonin; Ni | 2004 |
Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and anti-apoptotic effects.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Cytokines; Disease Models, Animal; Female; Inte | 2005 |
Therapeutic effects of melatonin on peritonitis-induced septic shock with multiple organ dysfunction syndrome in rats.
Topics: Animals; Antioxidants; Cecum; Disease Models, Animal; Ligation; Male; Melatonin; Multiple Organ Fail | 2008 |
Melatonin as a therapeutic agent in experimental endotoxic shock.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Escherichia coli; Female; L | 1996 |
Melatonin modulates mesenteric blood flow and TNFalpha concentrations after lipopolysaccharide challenge.
Topics: Animals; Female; Lipopolysaccharides; Melatonin; Mice; Mice, Inbred Strains; Random Allocation; Shoc | 2000 |
Melatonin prevents endotoxin-induced circulatory failure in rats.
Topics: Animals; Antioxidants; Aorta, Thoracic; Blotting, Western; Chemotaxis, Leukocyte; Endotoxemia; Esche | 2001 |