Page last updated: 2024-10-19

melatonin and Retinopathy of Prematurity

melatonin has been researched along with Retinopathy of Prematurity in 6 studies

Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" All preterm neonates with gestational age (GA) < 34 weeks or birth weight (BW) < 2000 grams eligible for ROP screening were randomized into oral melatonin (4 mg/kg) and oral 24% sucrose (0."9.51Comparison between oral melatonin and 24% sucrose for pain management during retinopathy of prematurity screening: a randomized controlled trial. ( Behura, SS; Dhanawat, A; Nayak, B; Panda, SK, 2022)
"Retinopathy of prematurity is a vision-threatening disease associated with retinal hypoxia-ischemia, leading to the death of retinal neurons and chronic neuronal degeneration."5.62Melatonin protects inner retinal neurons of newborn mice after hypoxia-ischemia. ( Cui, K; Huang, R; Liang, X; Lin, J; Liu, Y; Lu, X; Shi, Y; Tang, X; Xu, Y; Ye, D; Yu, S, 2021)
" All preterm neonates with gestational age (GA) < 34 weeks or birth weight (BW) < 2000 grams eligible for ROP screening were randomized into oral melatonin (4 mg/kg) and oral 24% sucrose (0."5.51Comparison between oral melatonin and 24% sucrose for pain management during retinopathy of prematurity screening: a randomized controlled trial. ( Behura, SS; Dhanawat, A; Nayak, B; Panda, SK, 2022)
"Urinary melatonin concentration below the certain cut-off values in the early neonatal period may serve as one of the predictors of adverse outcomes such as BPD, ROP, and late-onset sepsis in the late neonatal period in preterm infants."4.31The relationship of melatonin concentration in preterm infants and adverse outcomes in the late neonatal period. ( Kozak, K; Pavlyshyn, Н; Sarapuk, I, 2023)
"Intraperitoneal injections of exogenous melatonin during the development of the retinal vascular system in experimental rats has been shown in a number of experimental studies on the model of EROP to prevent the appearance of histological signs of the development of experimental retinopathy of prematurity (EROP), stabilize the blood-retinal barrier and have a pronounced antioxidant effect, but pathogenetic basis for these phenomena hasn't been studied."4.02[Pathogenetically oriented approach to prevention of retinopathy of prematurity (experimental study)]. ( Beznos, OV; Chesnokova, NB; Katargina, LA; Osipova, NA; Panova, AY, 2021)
"Retinopathy of prematurity is a vision-threatening disease associated with retinal hypoxia-ischemia, leading to the death of retinal neurons and chronic neuronal degeneration."1.62Melatonin protects inner retinal neurons of newborn mice after hypoxia-ischemia. ( Cui, K; Huang, R; Liang, X; Lin, J; Liu, Y; Lu, X; Shi, Y; Tang, X; Xu, Y; Ye, D; Yu, S, 2021)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Behura, SS1
Dhanawat, A1
Nayak, B1
Panda, SK1
Pavlyshyn, Н1
Sarapuk, I1
Kozak, K1
Huang, R1
Xu, Y2
Lu, X2
Tang, X1
Lin, J1
Cui, K1
Yu, S2
Shi, Y1
Ye, D1
Liu, Y1
Liang, X2
Katargina, LA1
Chesnokova, NB1
Beznos, OV1
Osipova, NA1
Panova, AY1
Hu, Y1
Yang, B1
Tsui, CK1
Lu, L1
Yzydorczyk, C1
Mitanchez, D1
Buffat, C1
Ligi, I1
Grandvuillemin, I1
Boubred, F1
Simeoni, U1

Reviews

1 review available for melatonin and Retinopathy of Prematurity

ArticleYear
[Oxidative stress after preterm birth: origins, biomarkers, and possible therapeutic approaches].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2015, Volume: 22, Issue:10

    Topics: Advanced Oxidation Protein Products; Aldehydes; Antioxidants; Biomarkers; Breast Feeding; Delivery R

2015

Trials

1 trial available for melatonin and Retinopathy of Prematurity

ArticleYear
Comparison between oral melatonin and 24% sucrose for pain management during retinopathy of prematurity screening: a randomized controlled trial.
    The Turkish journal of pediatrics, 2022, Volume: 64, Issue:6

    Topics: Birth Weight; Humans; Infant; Infant, Newborn; Melatonin; Pain; Pain Management; Pain Measurement; P

2022

Other Studies

4 other studies available for melatonin and Retinopathy of Prematurity

ArticleYear
The relationship of melatonin concentration in preterm infants and adverse outcomes in the late neonatal period.
    Biochemia medica, 2023, Feb-15, Volume: 33, Issue:1

    Topics: Bronchopulmonary Dysplasia; Humans; Infant; Infant, Newborn; Infant, Premature; Melatonin; Retinopat

2023
Melatonin protects inner retinal neurons of newborn mice after hypoxia-ischemia.
    Journal of pineal research, 2021, Volume: 71, Issue:1

    Topics: Animals; Animals, Newborn; Hypoxia; Ischemia; Melatonin; Mice; Mice, Inbred C57BL; Neuroprotective A

2021
[Pathogenetically oriented approach to prevention of retinopathy of prematurity (experimental study)].
    Vestnik oftalmologii, 2021, Volume: 137, Issue:3

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Humans; Infant, Newborn; Melatonin; Rats; Rats, W

2021
Melatonin attenuated retinal neovascularization and neuroglial dysfunction by inhibition of HIF-1α-VEGF pathway in oxygen-induced retinopathy mice.
    Journal of pineal research, 2018, Volume: 64, Issue:4

    Topics: Animals; Hypoxia-Inducible Factor 1, alpha Subunit; Melatonin; Mice; Mice, Inbred C57BL; Neuroglia;

2018