melatonin has been researched along with Reperfusion Injury in 245 studies
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This article summarizes the evidence that endogenously produced and exogenously administered melatonin reduces the degree of tissue damage and limits the biobehavioral deficits associated with experimental models of ischemia/reperfusion injury in the brain (i." | 8.82 | When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. ( Kilic, E; Kilic, U; Leon, J; Reiter, RJ; Tan, DX, 2005) |
| " In this study, the involvement of melatonin (MT) in modulating EMPs toxicity in the liver undergoing ischemia-reperfusion injury was investigated." | 8.31 | Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin. ( Abdennebi, HB; Banni, M; Jeddou, IB; Messaoudi, I; Minucci, S; Missawi, O; Reiter, RJ; Venditti, M; Zaouali, MA; Zitouni, N, 2023) |
| " Here, we explored the effects of nicotinamide mononucleotide (NMN)/melatonin combination therapy on mitochondrial biogenesis and fission/fusion, autophagy, and microRNA-499 in the aged rat heart with reperfusion injury." | 8.31 | The additive effects of nicotinamide mononucleotide and melatonin on mitochondrial biogenesis and fission/fusion, autophagy, and microRNA-499 in the aged rat heart with reperfusion injury. ( Badalzadeh, R; Hosseini, L; Høilund-Carlsen, PF; Mokhtari, B; Rajabi, M; Salehinasab, R, 2023) |
| "To investigate the mechanism of electroacupuncture in alleviating cerebral ischemia injury in cerebral ischemia-reperfusion rats by regulating melatonin - NOD-like receptor protein 3 (NLRP3) mediated pyroptosis." | 8.31 | [Electroacupuncture alleviates cerebral ischemia injury in rats by regulating melatonin-NLRP3 and inhibiting pyroptosis]. ( Chen, B; Liang, H; Liu, JJ; Luo, J; Ruan, S; Wang, F; Wang, YX; Yan, NW; Zhong, XY, 2023) |
| "The aim of this study was to investigate how melatonin administration for 3 days or 7 days following cerebral ischemia (CI) injury would affect autophagy and, therefore, survival in neurons of the penumbra region." | 8.31 | Melatonin Attenuates Cerebral Ischemia/Reperfusion Injury through Inducing Autophagy. ( Gul, M; Gul, S; Koc, A; Sandal, S; Tanbek, K; Yilmaz, U, 2023) |
| " Melatonin is neuroprotective against cerebral ischemia-reperfusion injury (CIRI) in non-DM, normoglycemic animals through anti-oxidant effect, anti-inflammation, and anti-apoptosis." | 8.31 | Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects. ( Cheung, RTF; Xu, Q, 2023) |
| " In this study, the neuroprotective effects of melatonin (Mel) on a rat model of cerebral ischemia/reperfusion injury (CIRI) were assessed by multi-parametric MRI combined with histopathological techniques for longitudinal monitoring of the lesion microenvironment." | 8.31 | Multi-parametric MRI assessment of melatonin regulating the polarization of microglia in rats after cerebral ischemia/reperfusion injury. ( An, L; Bi, F; Gong, P; Li, C; Li, Z; Song, X; Wang, X; Xiao, P; Yu, M; Zhang, M, 2023) |
| "To investigate the influence of melatonin on behavioral and neurological function of rats with focal cerebral ischemia-reperfusion injury via the JNK/FoxO3a/Bim pathway." | 8.12 | Influence of Melatonin on Behavioral and Neurological Function of Rats with Focal Cerebral Ischemia-Reperfusion Injury via the JNK/FoxO3a/Bim Pathway. ( Chen, X; Deng, Y; Lai, J; Ou, Y; Peng, X; Shen, X; Wu, H; Wu, L; Yao, Z; Zhu, H, 2022) |
| "To observe the effect of electroacupuncture(EA)at "Baihui"(GV20) and "Shenting" (GV24) on the expression of melatonin synthesis rate-limiting enzyme-arylalkylamine N-acetyltransferase(AANAT)in pineal gland of rats with focal cerebral ischemia-reperfusion injury, so as to explore the mechanism of EA underlying improving ischemia-reperfusion injury." | 8.12 | [Electroacupuncture ameliorates ischemic injury in cerebral ischemia-reperfusion rats by regulating endogenous melatonin and inhibiting the activation of astrocytes]. ( Chen, B; Liang, H; Luo, J; Ruan, S; Wang, F; Wang, YX; Zhong, XY, 2022) |
| " Previous studies have proved that melatonin could protect against cerebral ischemia-reperfusion (CIR) injury in non-diabetic stroke models; however, its roles and the underlying mechanisms against CIR injury in diabetic mice remain unknown." | 8.02 | Melatonin ameliorates cerebral ischemia-reperfusion injury in diabetic mice by enhancing autophagy via the SIRT1-BMAL1 pathway. ( Cao, Q; Gao, W; Li, BY; Liu, L; Xia, Z; Zeng, C; Zhao, B, 2021) |
| "Melatonin treatment following AGCI reduces pro-inflammatory factors, Gal-3, motility, and anxiety, therefore it should be considered as supplementary treatment following ischemic stroke." | 8.02 | Melatonin Decreases Circulating Levels of Galectin-3 and Cytokines, Motor Activity, and Anxiety Following Acute Global Cerebral Ischemia in Male Rats. ( Cervantes, M; Fenton-Navarro, B; Garduño Ríos, D; Letechipía-Vallejo, G; Torner, L, 2021) |
| "Sixty Sprague-Dawley rats were randomly divided into a sham group, ischemia-reperfusion injury group (I/R group), and melatonin-treated group (M + I/R group)." | 8.02 | Melatonin attenuates hepatic ischemia-reperfusion injury in rats by inhibiting NF-κB signaling pathway. ( Fan, ZL; Gao, Y; Huang, HF; Jin, L; Li, ZT; Lin, J; Zeng, Z, 2021) |
| "The current study compared the impact of pretreatment with melatonin and N-acetylcysteine (NAC) on the prevention of rat lung damage following intestinal ischemia-reperfusion (iIR)." | 8.02 | Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model. ( Brandão, JCM; Camargo, CR; Leite, AA; Marinho, M; Oliveira-Junior, IS; Reiter, RJ; Sakae, TM, 2021) |
| "Our data suggest a potential therapeutic effect of combined therapy with melatonin, mesenchymal stem cells and their exosomes to minimize renal ischemia-reperfusion injury in rats." | 7.96 | Combination therapy with melatonin, stem cells and extracellular vesicles is effective in limiting renal ischemia-reperfusion injury in a rat model. ( El-Magd, MA; El-Taweel, F; Elkholy, SS; Ghozy, A; Zahran, R, 2020) |
| "Melatonin (MT) has potential protective effect on cerebral ischemia-reperfusion injury (CIRI), but its underlying regulatory mechanism has not been identified." | 7.96 | Melatonin Plays a Protective Role by Regulating miR-26a-5p-NRSF and JAK2-STAT3 Pathway to Improve Autophagy, Inflammation and Oxidative Stress of Cerebral Ischemia-Reperfusion Injury. ( Cui, JW; Ma, X; Wei, LL; Yang, B; Zang, LE; Zhang, MY, 2020) |
| "To evaluate the protective effect of melatonin on ovarian ischemia reperfusion injury in a rat model." | 7.96 | Melatonin attenuates ovarian ischemia reperfusion injury in rats by decreasing oxidative stress index and peroxynitrite ( Bozdağ, Z; Bozdayi, MA; Demir, M; Ince, O; Kalyoncu, Ş; Taysi, S; Tuncer, M; Ulusal, H; Yilmaz, B, 2020) |
| "Previous literature has shown that melatonin plays a critical role in protecting against cerebral ischemia/reperfusion (I/R) injury." | 7.91 | Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation. ( Chen, H; Jin, J; Li, G; Liu, L; Tang, Z; Yin, P; Zhong, D, 2019) |
| "The article studies the effect of melatonin on the intensity of free radical oxidation, the functioning of the enzymatic components of the antioxidant system and their transcriptional regulation in rats with experimental cerebral ischemia/reperfusion of the brain." | 7.91 | Transcriptional Regulation of Antioxidant Enzymes Activity and Modulation of Oxidative Stress by Melatonin in Rats Under Cerebral Ischemia / Reperfusion Conditions. ( de Carvalho, MAP; Kryl'skii, ED; Popova, TN; Razuvaev, GA; Safonova, OA; Stolyarova, AO, 2019) |
| "This study demonstrated that melatonin pretreatment attenuated lung ischaemia-reperfusion injury via inhibition of oxidative stress, inflammation and apoptosis." | 7.88 | Melatonin attenuates lung ischaemia-reperfusion injury via inhibition of oxidative stress and inflammation. ( Wang, JJ; Wang, JS; Wang, ML; Wang, WD; Wei, CH; Zhang, J, 2018) |
| "The aim of this study was to investigate the effects of melatonin on intestinal anastomosis after intestinal ischemia/ reperfusion injury (IRI)." | 7.88 | Melatonin exhibits supportive effects on oxidants and anastomotic healing during intestinal ischemia/reperfusion injury. ( Çakır, E; Ersoy, ÖF; Özkan, N; Özsoy, Z, 2018) |
| "Our study results revealed that colchicine reduced testicular ischemia-reperfusion injury in experimental rat testis torsion model." | 7.85 | The effects of melatonin and colchicine on ischemia-reperfusion injury in experimental rat testicular torsion model. ( Ciftci, I; Gunduz, M; Karabağlı, P; Öztürk, B; Sekmenli, T; Tekin, G; Yılmaz, M, 2017) |
| " Group III: The melatonin was administered 30 min before clamping of the infrarenal AA then 30 min of ischemia and two hours of reperfusion was applied." | 7.83 | The protective effect of melatonin on remote organ liver ischemia and reperfusion injury following aortic clamping. ( Adali, F; Bali, A; Celep, RB; Celik, S; Gonul, Y; Koçak, A; Ozkececi, ZT; Ozsoy, M; Tosun, M, 2016) |
| "We conclude that melatonin prevents bacterial translocation while precluding the harmful effects of ischemia/reperfusion injury on intestinal tissues in a rat model of superior mesenteric artery occlusion." | 7.81 | The effect of melatonin on bacterial translocation following ischemia/reperfusion injury in a rat model of superior mesenteric artery occlusion. ( Aydin, B; Aydin, C; Berber, I; Birsen, O; Cevahir, N; Gumrukcu, G; Ozban, M; Yenisey, C, 2015) |
| "In this study, the relationship between the plasma levels of melatonin and intercellular adhesion molecule-1 (ICAM-1), which plays role in several intercellular interactions including inflammatory and immune responses, and early neurocognitive functions associated with ischaemia-reperfusion injury during open heart surgery is examined." | 7.81 | The Effect of Circadian Melatonin Levels on Inflammation and Neurocognitive Functions Following Coronary Bypass Surgery. ( Akçalı, A; Ali Elçi, M; Deniz, H; Geyik, S; Hafız, E; Murat Geyik, A; Yiğiter, R, 2015) |
| "Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema." | 7.80 | Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014) |
| "To compare the efficacy of ozone with melatonin, shown as the most powerful antioxidant in attenuation of testicular ischemia/reperfusion injury, in an experimental rat model of testicular torsion/detorsion." | 7.78 | Comparison of melatonin and ozone in the prevention of reperfusion injury following unilateral testicular torsion in rats. ( Benli Aksungar, F; Doğan Ekici, AI; Ekici, S; Lüleci, N; Öztürk, G; Sinanoğlu, O; Turan, G, 2012) |
| "The present study was designed to evaluate whether the administration of s-methylisothiourea and melatonin has protective potential in intestinal ischemia/reperfusion injury." | 7.76 | Evaluation of effects of s-methyl isothiourea and melatonin on intestinal ischemia/reperfusion injury in rats. ( Atabek, C; Demirin, H; Karaoglu, A; Kesik, V; Korkmaz, A; Kul, M; Ozler, M; Oztas, E; Sadir, S; Temiz, A; Tunc, T, 2010) |
| "In the present skeletal muscle acute I/R injury model, protective effects of melatonin against reperfusion injury have been revealed." | 7.76 | [Protective effects of melatonin on ischemia-reperfusion injury of skeletal muscle]. ( Bostan, B; Erdem, M; Erdoğan, H; Güneş, T; Köseoğlu, RD; Özkan, F; Özyurt, H; Sen, C, 2010) |
| " The aim of this study was to investigate the effects of two antioxidant agents, carnosine and melatonin, in rat liver ischemia-reperfusion injury." | 7.75 | The protective effects of carnosine and melatonin in ischemia-reperfusion injury in the rat liver. ( Baykara, B; Ormen, M; Ozogul, C; Pekcetin, C; Sagol, O; Tekmen, I; Tuncel, P; Ulukus, C, 2009) |
| "To explore the effect of electroacupuncture (EA) in resisting acute cerebral ischemia-reperfusion injury (CI-RI) via anti-oxidation of melatonin (MT)." | 7.74 | [Involvement of melatonin in the adjusting effect of electroacupuncture in resisting oxygen stress in cerebral ischemia-reperfusion injury rats]. ( Li, ZR; Niu, WM; Shen, MH, 2008) |
| "To investigate the protective effect of melatonin on liver after intestinal ischemia-reperfusion injury in rats." | 7.74 | Melatonin protects liver from intestine ischemia reperfusion injury in rats. ( Gu, X; Li, JY; Qin, YM; Yin, HZ; Zhang, WH; Zhou, Y, 2008) |
| "The effect of melatonin on reperfusion arrhythmias and postischemic contractile dysfunction was studied in the isolated rat heart." | 7.73 | Ischemia-reperfusion injury--antiarrhythmic effect of melatonin associated with reduced recovering of contractility. ( Béder, I; Pancza, D; Styk, J; Vazan, R, 2005) |
| "Pretreatment with melatonin increased NO bioavailability and decreased endothelin expression, and consequently played a protective role in preserving both liver function and structure during ischemia and reperfusion injury." | 7.73 | Melatonin abates liver ischemia/reperfusion injury by improving the balance between nitric oxide and endothelin. ( Li, JY; Zhang, WH; Zhou, Y, 2006) |
| " Herein, we examined the effect of melatonin on the neutrophil apoptosis in ischemia and reperfusion of the human liver." | 7.72 | Altered neutrophil apoptosis activity is reversed by melatonin in liver ischemia-reperfusion. ( Chen, HM; Chen, JC; Chiu, TF; Ng, CJ, 2003) |
| "This study was designed to study the effects of Melatonin (Mel) and N-Acetylcystein (NAC) on hepatic ischemia/reperfusion (I/R) injury in rats." | 7.72 | Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion. ( Arbak, S; Ayanoğlu-Dülger, G; Ersoy, Y; Kaçmaz, A; Sehirli, AO; Sener, G; Tosun, O, 2003) |
| " melatonin (4 + 4 mg/kg, after induction of ischemia and at reperfusion onset) administered either alone or in combination with the thrombolytic tissue-plasminogen activator (t-PA, 10 mg/kg), on cerebral laser Doppler flow (LDF) and ischemic injury were studied after 30 min of middle cerebral artery (MCA) thread occlusion in male C57BL/6 mice." | 7.72 | Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator. ( Hermann, DM; Kilic, E; Kilic, U; Reiter, RJ; Yulug, B, 2004) |
| "To investigate the effects of melatonin (MT) on histology and behavioral tests during global cerebral ischemia-reperfusion in gerbils." | 7.71 | [The protective effects of melatonin on global cerebral ischemia-reperfusion injury in gerbils]. ( Dai, TJ; Gu, SL; Guo, JD; Xing, SH; Zhang, J, 2002) |
| "In this model, exogenously administered melatonin effectively protected lungs from reperfusion injury after prolonged ischemia." | 7.71 | Melatonin attenuates posttransplant lung ischemia-reperfusion injury. ( Boehler, A; Dutly, A; Inci, D; Inci, I; Weder, W, 2002) |
| " As an antioxidant, melatonin administration might be helpful in decreasing post-operative morbidity by decreasing reperfusion injury of lungs." | 7.71 | Effects of melatonin on noncardiogenic pulmonary edema secondary to adnexial ischemia-reperfusion in guinea pig. ( Ayar, A; Bildirici, I; Celik, H; Cikim, G; Ozercan, I; Simsek, M; Tug, N, 2002) |
| "Ischemic reperfusion injury (IRI) causes cellular damage and dysfunction." | 7.11 | Effect of Preoperative Administration of Oral Melatonin on Pneumatic Tourniquet-Induced Ischemia-Reperfusion Injury in Orthopedic Surgery of Lower Extremities: A Randomized Clinical Trial. ( Bagheri, N; Jouybar, R; Khademi, S; Razmjooie, S, 2022) |
| "Melatonin was associated with improvement in renal transplantation, since the serum level of neutrophil gelatinase-associated lipocalin, as a renal functional marker, significantly decreased (P < ." | 6.90 | The effect of oral melatonin on renal ischemia-reperfusion injury in transplant patients: A double-blind, randomized controlled trial. ( Alirezaei, A; Argani, H; Dastmalchi, S; Ghorbanihaghjo, A; Haiaty, S; Hosseini, L; Jabarpour, M; Nazari Soltan Ahmad, S; Panah, F; Rashtchizadeh, N; Rezaeian, R; Sanajou, D, 2019) |
| " Special attention has been paid to the advantageous characteristics of melatonin as a neuroprotective drug: bioavailability into brain cells and cellular organelles targeted by morpho-functional derangement; effectiveness in exerting several neuroprotective actions, which can be amplified and prolonged by its metabolites, through direct and indirect antioxidant activity; prevention and reversal of mitochondrial malfunction, reducing inflammation, derangement of cytoskeleton organization, and pro-apoptotic cell signaling; lack of interference with thrombolytic and neuroprotective actions of other drugs; and an adequate safety profile." | 6.44 | Melatonin and ischemia-reperfusion injury of the brain. ( Cervantes, M; Letechipía-Vallejo, G; Moralí, G, 2008) |
| "Melatonin has been shown to be effective in arresting neurodegenerative phenomena seen in experimental models of Alzheimer's disease, Parkinsonism and ischemic stroke." | 6.43 | Role of melatonin in neurodegenerative diseases. ( Cardinali, DP; Esquifino, AI; Hardeland, R; Maestroni, GJ; Pandi-Perumal, SR; Srinivasan, V, 2005) |
| "Treatment with melatonin has been shown to prevent in vivo the delayed vascular decompensation and the cellular energetic failure associated with shock, inflammation and ischemia/reperfusion injury." | 6.41 | Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. ( Cuzzocrea, S; Reiter, RJ, 2001) |
| "Obesity is well-established as a common comorbidity in ischemic stroke." | 5.91 | Melatonin modulates the aggravation of pyroptosis, necroptosis, and neuroinflammation following cerebral ischemia and reperfusion injury in obese rats. ( Govitrapong, P; Sengking, J; Tocharus, C; Tocharus, J; Yawoot, N, 2023) |
| "Melatonin (MT) is an indoleamine hormone that can counteract ischemia‑induced organ injury through its antioxidant effects." | 5.62 | Exogenous melatonin alleviates hemorrhagic shock‑induced hepatic ischemic injury in rats by inhibiting the NF‑κB/IκBα signaling pathway. ( Cai, QQ; Li, HW; Wu, XL; Yang, ZH; Ying, P, 2021) |
| "Diabetic patients are more vulnerable to cerebral ischemia-reperfusion (CIR) injury and have a worse prognosis and higher mortality after ischemic stroke than non-diabetic counterparts." | 5.62 | Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway. ( Cao, Q; Gao, W; Li, B; Liu, L; Xia, Z; Zhao, B, 2021) |
| "Melatonin has anti-inflammatory, anti-oxidative and anti-apoptotic effects against various diseases." | 5.56 | Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion. ( Bai, YP; Chen, Y; Feng, JG; Jia, J; Liu, KX; Yang, B; Zhang, LY; Zhou, J, 2020) |
| "Melatonin treatment significantly decreased infarct volume and cerebral apoptosis; mitigated endoplasmic reticulum stress and mitochondrial dysfunction; and inhibited CI/R injury-induced oxidative/nitrative stress and nuclear factor-κB activation, which was eradicated in RORα-deficient mice." | 5.56 | The circadian nuclear receptor RORα negatively regulates cerebral ischemia-reperfusion injury and mediates the neuroprotective effects of melatonin. ( Ai, L; Gao, L; Gao, Y; Petersen, L; Pu, J; Qin, Z; Tong, R; Yan, Y; Zang, M; Zhao, Y; Zhong, F; Zhu, C, 2020) |
| "Melatonin treatment also effectively decreased neuron apoptosis resulting from OGD-induced neuron injury." | 5.48 | Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress. ( Chang, CC; Chen, TY; Huang, SY; Hung, CY; Hung, HY; Lee, EJ; Lin, YW; Tai, SH, 2018) |
| "Melatonin is a free radical scavenger and broad-spectrum antioxidant with immunomodulatory effects." | 5.42 | Melatonin prevents lung injury induced by hepatic ischemia-reperfusion through anti-inflammatory and anti-apoptosis effects. ( An, H; Jiang, C; Yang, B; Zhang, H; Zhao, D; Zhou, L, 2015) |
| "It contributes to the development of acute renal failure." | 5.40 | Effect of a combined treatment with erythropoietin and melatonin on renal ischemia reperfusion injury in male rats. ( Ahmadiasl, N; Alihemati, A; Azimian, E; Banaei, S; Baradaran, B, 2014) |
| "Melatonin treatment significantly reduced the level of serum alanine aminotransferase activity." | 5.37 | Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway. ( Kang, JW; Koh, EJ; Lee, SM, 2011) |
| "Melatonin is a potent free radical scavenger and a strong antioxidant." | 5.36 | Proteomic identification of proteins differentially expressed by melatonin in hepatic ischemia-reperfusion injury. ( Cho, EH; Koh, PO, 2010) |
| "Melatonin treatment reversed all these oxidant and antioxidant parameters to control values as well as serum liver enzymes." | 5.35 | Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus. ( Fadillioglu, E; Gursul, C; Iraz, M; Kurcer, Z; Parlakpinar, H, 2008) |
| "Melatonin is a potent scavenger of reactive oxygen and nitrogen species." | 5.35 | Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation. ( Bruns, H; Büchler, MW; Gross, ML; Hoffmann, K; Li, Z; Mohr, E; Nickkholgh, A; Schemmer, P; Yi, X; Zorn, M, 2009) |
| "Both Melatonin and 1400W were efficient in ameliorating experimental I/R injury of the kidneys." | 5.35 | Comparison of the efficacy of melatonin and 1400W on renal ischemia/reperfusion injury: a role for inhibiting iNOS. ( Akgul, EO; Cayci, T; Cetiner, S; Ersoz, N; Guven, A; Korkmaz, A; Oztas, E; Turk, E; Uysal, B, 2009) |
| "Melatonin treatment decreased lipid and protein oxidation and ameloriated histopathologic alterations induced by IR without any change in proinflammatory cytokine levels." | 5.35 | Effect of melatonin on testicular ischemia/reperfusion injury in rats: is this effect related to the proinflammatory cytokines? ( Aksoy, N; Baba, F; Celik, N; Kurcer, Z; Oguz, E; Ozbilge, H, 2008) |
| "The melatonin-treated rats showed markedly fewer apoptotic (TUNEL positive) cells and DNA fragmentation than did the I/R rats." | 5.35 | Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver. ( Kim, SH; Lee, SM, 2008) |
| "Melatonin is a potent scavenger of ROS." | 5.35 | Melatonin protects from hepatic reperfusion injury through inhibition of IKK and JNK pathways and modification of cell proliferation. ( Büchler, MW; Hoffmann, K; Kern, M; Liang, R; Nickkholgh, A; Schemmer, P; Schneider, H; Sobirey, M; Zorn, M, 2009) |
| "Melatonin treatment also resulted with MDA formation (P=0." | 5.34 | The effects of prophylactic zinc and melatonin application on experimental spinal cord ischemia-reperfusion injury in rabbits: experimental study. ( Abuşoglu, S; Avunduk, MC; Baysefer, A; Ciçek, O; Kalkan, E; Kalkan, SS; Unlü, A, 2007) |
| "Melatonin in particular was effective to reverse hot ischemia of kidney by its antioxidant effects." | 5.34 | The protective effects of melatonin and vitamin E against renal ischemia-reperfusion injury in rats. ( Aktoz, T; Alagol, B; Atakan, IH; Aydogdu, N; Huseyinova, G; Yalcin, O, 2007) |
| "The purpose of this study was to investigate the effects of chronic administration of melatonin on renal ischemia/reperfusion (IR) injury in streptozotocin (STZ)-induced diabetic rats." | 5.34 | Protective effects of chronic melatonin treatment against renal ischemia/reperfusion injury in streptozotocin-induced diabetic rats. ( Baba, F; Fadillioglu, E; Gül, M; Iraz, M; Kurcer, Z; Parlakpinar, H; Tasdemir, S; Vardi, N, 2007) |
| "Melatonin has a protective effect against I/R injury in skeletal muscle and may reduce the incidence of compartment syndrome, especially after acute or chronic peripheral arterial occlusions." | 5.33 | Melatonin protects against ischemia/reperfusion injury in skeletal muscle. ( Ercan, F; Erkanli, G; Erkanli, K; Kayalar, N; Kirali, K; Sener, G, 2005) |
| "Melatonin was intraperitoneally administered before or/and after IR injury." | 5.33 | Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas. ( Briceño, J; Collado, JA; Cruz, A; Montilla, P; Muñoz-Casares, FC; Muñoz-Castañeda, JR; Muntané, J; Ortega, R; Padillo, FJ; Pera, C; Túnez, I, 2006) |
| "Melatonin or vehicle was administered 1 h before flap elevation and was continued for 6 days after ischemia." | 5.33 | The protective effect of melatonin on ischemia-reperfusion injury in the groin (inferior epigastric) flap model in rats. ( Aydogan, H; Bay-Karabulut, A; Celik, M; Gurlek, A; Parlakpinar, H, 2006) |
| "Melatonin was administered either 10 min before aortic occlusion or 10 min after the clamp was removed." | 5.32 | Protective effect of melatonin on experimental spinal cord ischemia. ( Aydemir, S; Colak, A; Erten, SF; Kocak, A; Ozdemir, I; Reeder, BS, 2003) |
| "Melatonin treatment reversed the I/R-induced increase and decrease in MDA and SOD levels, respectively." | 5.32 | Beneficial effects of melatonin on reperfusion injury in rat sciatic nerve. ( Aktas, RG; Arslan, SO; Coskun, O; Ozacmak, VH; Ozen, OA; Sayan, H; Sezen, SC, 2004) |
| "Malondialdehyde (MDA) levels were assayed as an index of lipid peroxidation reflecting free radical reaction in the intestine." | 5.31 | The role of melatonin in prevention of intestinal ischemia-reperfusion injury in rats. ( Demirbağ, M; Kazez, A; Ozercan, IH; Sağlam, M; Ustündağ, B, 2000) |
| "Melatonin was either infused during both the ischemia and reperfusion periods or only late in the ischemia period and throughout reperfusion." | 5.30 | Ischemia/reperfusion-induced arrhythmias in the isolated rat heart: prevention by melatonin. ( El-Sokkary, GH; Kim, SJ; Manchester, LC; Qi, W; Reiter, RJ; Tan, DX, 1998) |
| "This article summarizes the evidence that endogenously produced and exogenously administered melatonin reduces the degree of tissue damage and limits the biobehavioral deficits associated with experimental models of ischemia/reperfusion injury in the brain (i." | 4.82 | When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. ( Kilic, E; Kilic, U; Leon, J; Reiter, RJ; Tan, DX, 2005) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| " In this study, the involvement of melatonin (MT) in modulating EMPs toxicity in the liver undergoing ischemia-reperfusion injury was investigated." | 4.31 | Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin. ( Abdennebi, HB; Banni, M; Jeddou, IB; Messaoudi, I; Minucci, S; Missawi, O; Reiter, RJ; Venditti, M; Zaouali, MA; Zitouni, N, 2023) |
| " Here, we explored the effects of nicotinamide mononucleotide (NMN)/melatonin combination therapy on mitochondrial biogenesis and fission/fusion, autophagy, and microRNA-499 in the aged rat heart with reperfusion injury." | 4.31 | The additive effects of nicotinamide mononucleotide and melatonin on mitochondrial biogenesis and fission/fusion, autophagy, and microRNA-499 in the aged rat heart with reperfusion injury. ( Badalzadeh, R; Hosseini, L; Høilund-Carlsen, PF; Mokhtari, B; Rajabi, M; Salehinasab, R, 2023) |
| "To investigate the mechanism of electroacupuncture in alleviating cerebral ischemia injury in cerebral ischemia-reperfusion rats by regulating melatonin - NOD-like receptor protein 3 (NLRP3) mediated pyroptosis." | 4.31 | [Electroacupuncture alleviates cerebral ischemia injury in rats by regulating melatonin-NLRP3 and inhibiting pyroptosis]. ( Chen, B; Liang, H; Liu, JJ; Luo, J; Ruan, S; Wang, F; Wang, YX; Yan, NW; Zhong, XY, 2023) |
| "The aim of this study was to investigate how melatonin administration for 3 days or 7 days following cerebral ischemia (CI) injury would affect autophagy and, therefore, survival in neurons of the penumbra region." | 4.31 | Melatonin Attenuates Cerebral Ischemia/Reperfusion Injury through Inducing Autophagy. ( Gul, M; Gul, S; Koc, A; Sandal, S; Tanbek, K; Yilmaz, U, 2023) |
| " Melatonin is neuroprotective against cerebral ischemia-reperfusion injury (CIRI) in non-DM, normoglycemic animals through anti-oxidant effect, anti-inflammation, and anti-apoptosis." | 4.31 | Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects. ( Cheung, RTF; Xu, Q, 2023) |
| " In this study, the neuroprotective effects of melatonin (Mel) on a rat model of cerebral ischemia/reperfusion injury (CIRI) were assessed by multi-parametric MRI combined with histopathological techniques for longitudinal monitoring of the lesion microenvironment." | 4.31 | Multi-parametric MRI assessment of melatonin regulating the polarization of microglia in rats after cerebral ischemia/reperfusion injury. ( An, L; Bi, F; Gong, P; Li, C; Li, Z; Song, X; Wang, X; Xiao, P; Yu, M; Zhang, M, 2023) |
| "Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)." | 4.21 | ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022) |
| "The aim of this experiment was to investigate the role of melatonin and spirulina on multiorgan damage induced by ischemia/reperfusion injury (IR) in a rat model." | 4.12 | Protective role of melatonin and spirulina in aortic occlusion-reperfusion model in rats. ( Akduman, H; Dilli, D; Salar, S; Sarı, E; Taşoğlu, İ; Tümer, NB; Yumuşak, N, 2022) |
| "To investigate the influence of melatonin on behavioral and neurological function of rats with focal cerebral ischemia-reperfusion injury via the JNK/FoxO3a/Bim pathway." | 4.12 | Influence of Melatonin on Behavioral and Neurological Function of Rats with Focal Cerebral Ischemia-Reperfusion Injury via the JNK/FoxO3a/Bim Pathway. ( Chen, X; Deng, Y; Lai, J; Ou, Y; Peng, X; Shen, X; Wu, H; Wu, L; Yao, Z; Zhu, H, 2022) |
| "To observe the effect of electroacupuncture(EA)at "Baihui"(GV20) and "Shenting" (GV24) on the expression of melatonin synthesis rate-limiting enzyme-arylalkylamine N-acetyltransferase(AANAT)in pineal gland of rats with focal cerebral ischemia-reperfusion injury, so as to explore the mechanism of EA underlying improving ischemia-reperfusion injury." | 4.12 | [Electroacupuncture ameliorates ischemic injury in cerebral ischemia-reperfusion rats by regulating endogenous melatonin and inhibiting the activation of astrocytes]. ( Chen, B; Liang, H; Luo, J; Ruan, S; Wang, F; Wang, YX; Zhong, XY, 2022) |
| " This study aimed to determine the rate of fat peroxidation and tissue protein as an indicator of tissue degradation after ischemia and reperfusion following induction of superior mesenteric artery occlusion in the intestine and to evaluate the protective effect of melatonin as a free radical scavenger and antioxidants in rats." | 4.12 | Protective effect of melatonin as an antioxidant in the intestine of rats with superior mesenteric arterial occlusion. ( Xi, Z; Yu, B; Yuan, X, 2022) |
| " Previous studies have proved that melatonin could protect against cerebral ischemia-reperfusion (CIR) injury in non-diabetic stroke models; however, its roles and the underlying mechanisms against CIR injury in diabetic mice remain unknown." | 4.02 | Melatonin ameliorates cerebral ischemia-reperfusion injury in diabetic mice by enhancing autophagy via the SIRT1-BMAL1 pathway. ( Cao, Q; Gao, W; Li, BY; Liu, L; Xia, Z; Zeng, C; Zhao, B, 2021) |
| "Melatonin treatment following AGCI reduces pro-inflammatory factors, Gal-3, motility, and anxiety, therefore it should be considered as supplementary treatment following ischemic stroke." | 4.02 | Melatonin Decreases Circulating Levels of Galectin-3 and Cytokines, Motor Activity, and Anxiety Following Acute Global Cerebral Ischemia in Male Rats. ( Cervantes, M; Fenton-Navarro, B; Garduño Ríos, D; Letechipía-Vallejo, G; Torner, L, 2021) |
| "Sixty Sprague-Dawley rats were randomly divided into a sham group, ischemia-reperfusion injury group (I/R group), and melatonin-treated group (M + I/R group)." | 4.02 | Melatonin attenuates hepatic ischemia-reperfusion injury in rats by inhibiting NF-κB signaling pathway. ( Fan, ZL; Gao, Y; Huang, HF; Jin, L; Li, ZT; Lin, J; Zeng, Z, 2021) |
| "The current study compared the impact of pretreatment with melatonin and N-acetylcysteine (NAC) on the prevention of rat lung damage following intestinal ischemia-reperfusion (iIR)." | 4.02 | Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model. ( Brandão, JCM; Camargo, CR; Leite, AA; Marinho, M; Oliveira-Junior, IS; Reiter, RJ; Sakae, TM, 2021) |
| "Our data suggest a potential therapeutic effect of combined therapy with melatonin, mesenchymal stem cells and their exosomes to minimize renal ischemia-reperfusion injury in rats." | 3.96 | Combination therapy with melatonin, stem cells and extracellular vesicles is effective in limiting renal ischemia-reperfusion injury in a rat model. ( El-Magd, MA; El-Taweel, F; Elkholy, SS; Ghozy, A; Zahran, R, 2020) |
| "Melatonin (MT) has potential protective effect on cerebral ischemia-reperfusion injury (CIRI), but its underlying regulatory mechanism has not been identified." | 3.96 | Melatonin Plays a Protective Role by Regulating miR-26a-5p-NRSF and JAK2-STAT3 Pathway to Improve Autophagy, Inflammation and Oxidative Stress of Cerebral Ischemia-Reperfusion Injury. ( Cui, JW; Ma, X; Wei, LL; Yang, B; Zang, LE; Zhang, MY, 2020) |
| "To evaluate the protective effect of melatonin on ovarian ischemia reperfusion injury in a rat model." | 3.96 | Melatonin attenuates ovarian ischemia reperfusion injury in rats by decreasing oxidative stress index and peroxynitrite ( Bozdağ, Z; Bozdayi, MA; Demir, M; Ince, O; Kalyoncu, Ş; Taysi, S; Tuncer, M; Ulusal, H; Yilmaz, B, 2020) |
| "Previous literature has shown that melatonin plays a critical role in protecting against cerebral ischemia/reperfusion (I/R) injury." | 3.91 | Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation. ( Chen, H; Jin, J; Li, G; Liu, L; Tang, Z; Yin, P; Zhong, D, 2019) |
| "The article studies the effect of melatonin on the intensity of free radical oxidation, the functioning of the enzymatic components of the antioxidant system and their transcriptional regulation in rats with experimental cerebral ischemia/reperfusion of the brain." | 3.91 | Transcriptional Regulation of Antioxidant Enzymes Activity and Modulation of Oxidative Stress by Melatonin in Rats Under Cerebral Ischemia / Reperfusion Conditions. ( de Carvalho, MAP; Kryl'skii, ED; Popova, TN; Razuvaev, GA; Safonova, OA; Stolyarova, AO, 2019) |
| "This study demonstrated that melatonin pretreatment attenuated lung ischaemia-reperfusion injury via inhibition of oxidative stress, inflammation and apoptosis." | 3.88 | Melatonin attenuates lung ischaemia-reperfusion injury via inhibition of oxidative stress and inflammation. ( Wang, JJ; Wang, JS; Wang, ML; Wang, WD; Wei, CH; Zhang, J, 2018) |
| "The aim of this study was to investigate the effects of melatonin on intestinal anastomosis after intestinal ischemia/ reperfusion injury (IRI)." | 3.88 | Melatonin exhibits supportive effects on oxidants and anastomotic healing during intestinal ischemia/reperfusion injury. ( Çakır, E; Ersoy, ÖF; Özkan, N; Özsoy, Z, 2018) |
| "Our study results revealed that colchicine reduced testicular ischemia-reperfusion injury in experimental rat testis torsion model." | 3.85 | The effects of melatonin and colchicine on ischemia-reperfusion injury in experimental rat testicular torsion model. ( Ciftci, I; Gunduz, M; Karabağlı, P; Öztürk, B; Sekmenli, T; Tekin, G; Yılmaz, M, 2017) |
| " Group III: The melatonin was administered 30 min before clamping of the infrarenal AA then 30 min of ischemia and two hours of reperfusion was applied." | 3.83 | The protective effect of melatonin on remote organ liver ischemia and reperfusion injury following aortic clamping. ( Adali, F; Bali, A; Celep, RB; Celik, S; Gonul, Y; Koçak, A; Ozkececi, ZT; Ozsoy, M; Tosun, M, 2016) |
| "We conclude that melatonin prevents bacterial translocation while precluding the harmful effects of ischemia/reperfusion injury on intestinal tissues in a rat model of superior mesenteric artery occlusion." | 3.81 | The effect of melatonin on bacterial translocation following ischemia/reperfusion injury in a rat model of superior mesenteric artery occlusion. ( Aydin, B; Aydin, C; Berber, I; Birsen, O; Cevahir, N; Gumrukcu, G; Ozban, M; Yenisey, C, 2015) |
| "In this study, the relationship between the plasma levels of melatonin and intercellular adhesion molecule-1 (ICAM-1), which plays role in several intercellular interactions including inflammatory and immune responses, and early neurocognitive functions associated with ischaemia-reperfusion injury during open heart surgery is examined." | 3.81 | The Effect of Circadian Melatonin Levels on Inflammation and Neurocognitive Functions Following Coronary Bypass Surgery. ( Akçalı, A; Ali Elçi, M; Deniz, H; Geyik, S; Hafız, E; Murat Geyik, A; Yiğiter, R, 2015) |
| "Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema." | 3.80 | Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014) |
| "Melatonin protected the kidneys submitted to I/R in rats without hyperglycemia; however, this did not occur when the I/R lesion was associated with hyperglycemia." | 3.80 | Evaluation of renal protection from high doses of melatonin in an experimental model of renal ischemia and reperfusion in hyperglycemic rats. ( Castiglia, YM; de Carvalho, LR; de Souza, AV; Deffune, E; Domingues, MA; Golim, MA; Vianna, IG; Vianna, PT, 2014) |
| "The results showed that thiamine pyrophosphate prevented ischemia/reperfusion injury-related infertility, but melatonin did not provide adequate prevention." | 3.79 | Use of thiamine pyrophosphate to prevent infertility developing in rats undergoing unilateral ovariectomy and with ischemia reperfusion induced in the contralateral ovary. ( Borekci, B; Cetin, N; Gul, MA; Turan, MI; Yapca, OE, 2013) |
| " The effect of melatonin on liver ischemia/reperfusion injury in a rat model of obesity and hepatic steatosis has been investigated." | 3.79 | Melatonin treatment protects liver of Zucker rats after ischemia/reperfusion by diminishing oxidative stress and apoptosis. ( Bitoun, S; Cuesta, S; Ibarrola, C; Kireev, R; Moreno, E; Tejerina, A; Tresguerres, JA; Vara, E, 2013) |
| "Several pathological conditions, including hypertension, atherosclerosis, diabetes, ischemia/reperfusion injury and nicotine-induced vasculopathy, are associated with vascular endothelial dysfunction characterized by altered secretory output of endothelial cells." | 3.79 | Vascular endothelial cells and dysfunctions: role of melatonin. ( Castrezzati, S; Favero, G; Foglio, E; Lonati, C; Rezzani, R; Rodella, LF; Rossini, C, 2013) |
| "To compare the efficacy of ozone with melatonin, shown as the most powerful antioxidant in attenuation of testicular ischemia/reperfusion injury, in an experimental rat model of testicular torsion/detorsion." | 3.78 | Comparison of melatonin and ozone in the prevention of reperfusion injury following unilateral testicular torsion in rats. ( Benli Aksungar, F; Doğan Ekici, AI; Ekici, S; Lüleci, N; Öztürk, G; Sinanoğlu, O; Turan, G, 2012) |
| "The present study was designed to evaluate whether the administration of s-methylisothiourea and melatonin has protective potential in intestinal ischemia/reperfusion injury." | 3.76 | Evaluation of effects of s-methyl isothiourea and melatonin on intestinal ischemia/reperfusion injury in rats. ( Atabek, C; Demirin, H; Karaoglu, A; Kesik, V; Korkmaz, A; Kul, M; Ozler, M; Oztas, E; Sadir, S; Temiz, A; Tunc, T, 2010) |
| "In the present skeletal muscle acute I/R injury model, protective effects of melatonin against reperfusion injury have been revealed." | 3.76 | [Protective effects of melatonin on ischemia-reperfusion injury of skeletal muscle]. ( Bostan, B; Erdem, M; Erdoğan, H; Güneş, T; Köseoğlu, RD; Özkan, F; Özyurt, H; Sen, C, 2010) |
| " The aim of this study was to investigate the effects of two antioxidant agents, carnosine and melatonin, in rat liver ischemia-reperfusion injury." | 3.75 | The protective effects of carnosine and melatonin in ischemia-reperfusion injury in the rat liver. ( Baykara, B; Ormen, M; Ozogul, C; Pekcetin, C; Sagol, O; Tekmen, I; Tuncel, P; Ulukus, C, 2009) |
| "To explore the effect of electroacupuncture (EA) in resisting acute cerebral ischemia-reperfusion injury (CI-RI) via anti-oxidation of melatonin (MT)." | 3.74 | [Involvement of melatonin in the adjusting effect of electroacupuncture in resisting oxygen stress in cerebral ischemia-reperfusion injury rats]. ( Li, ZR; Niu, WM; Shen, MH, 2008) |
| "To investigate the protective effect of melatonin on liver after intestinal ischemia-reperfusion injury in rats." | 3.74 | Melatonin protects liver from intestine ischemia reperfusion injury in rats. ( Gu, X; Li, JY; Qin, YM; Yin, HZ; Zhang, WH; Zhou, Y, 2008) |
| "The effect of melatonin on reperfusion arrhythmias and postischemic contractile dysfunction was studied in the isolated rat heart." | 3.73 | Ischemia-reperfusion injury--antiarrhythmic effect of melatonin associated with reduced recovering of contractility. ( Béder, I; Pancza, D; Styk, J; Vazan, R, 2005) |
| "To investigate the neuroprotective effect of melatonin (MT) on retinal ganglion cells (RGCs) in rats with ischemia reperfusion injury (RIR), 24 healthy SD rats were randomly divided into two groups: group A and group B." | 3.73 | Neuroprotective effect of melatonin on retinal ganglion cells in rats. ( Cao, Y; Hu, Y; Tang, Q, 2006) |
| "Pretreatment with melatonin increased NO bioavailability and decreased endothelin expression, and consequently played a protective role in preserving both liver function and structure during ischemia and reperfusion injury." | 3.73 | Melatonin abates liver ischemia/reperfusion injury by improving the balance between nitric oxide and endothelin. ( Li, JY; Zhang, WH; Zhou, Y, 2006) |
| " Herein, we examined the effect of melatonin on the neutrophil apoptosis in ischemia and reperfusion of the human liver." | 3.72 | Altered neutrophil apoptosis activity is reversed by melatonin in liver ischemia-reperfusion. ( Chen, HM; Chen, JC; Chiu, TF; Ng, CJ, 2003) |
| "This study was designed to study the effects of Melatonin (Mel) and N-Acetylcystein (NAC) on hepatic ischemia/reperfusion (I/R) injury in rats." | 3.72 | Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion. ( Arbak, S; Ayanoğlu-Dülger, G; Ersoy, Y; Kaçmaz, A; Sehirli, AO; Sener, G; Tosun, O, 2003) |
| " melatonin (4 + 4 mg/kg, after induction of ischemia and at reperfusion onset) administered either alone or in combination with the thrombolytic tissue-plasminogen activator (t-PA, 10 mg/kg), on cerebral laser Doppler flow (LDF) and ischemic injury were studied after 30 min of middle cerebral artery (MCA) thread occlusion in male C57BL/6 mice." | 3.72 | Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator. ( Hermann, DM; Kilic, E; Kilic, U; Reiter, RJ; Yulug, B, 2004) |
| "Melatonin, secreted by the pineal gland, is a multifunctional agent which (i) protects tissues from damage through free radical scavenging and attenuates ischemia/reperfusion injury in organ grafts; (ii) acts synergistically with cellular antioxidants; and (iii) displays complex, dose-dependent immunoenhancing and suppressing effects in vitro and in vivo." | 3.72 | Melatonin in vivo prolongs cardiac allograft survival in rats. ( Härter, L; Inci, I; Jung, FJ; Keel, M; Korom, S; Lardinois, D; Schneiter, D; Weder, W; Yang, L, 2004) |
| "To investigate the effects of melatonin (MT) on histology and behavioral tests during global cerebral ischemia-reperfusion in gerbils." | 3.71 | [The protective effects of melatonin on global cerebral ischemia-reperfusion injury in gerbils]. ( Dai, TJ; Gu, SL; Guo, JD; Xing, SH; Zhang, J, 2002) |
| "Melatonin effectively reduced damage induced by chemical hypoxia in adult cardiomyocytes, probably by virtue of its effects on reactive oxygen species generation and intracellular Ca2+ accumulation." | 3.71 | Melatonin protects against ischaemic-reperfusion myocardial damage. ( Cillie, C; Genade, S; Harper, I; Huisamen, B; Lochner, A; Moolman, J; Salie, R, 2001) |
| "In this model, exogenously administered melatonin effectively protected lungs from reperfusion injury after prolonged ischemia." | 3.71 | Melatonin attenuates posttransplant lung ischemia-reperfusion injury. ( Boehler, A; Dutly, A; Inci, D; Inci, I; Weder, W, 2002) |
| " As an antioxidant, melatonin administration might be helpful in decreasing post-operative morbidity by decreasing reperfusion injury of lungs." | 3.71 | Effects of melatonin on noncardiogenic pulmonary edema secondary to adnexial ischemia-reperfusion in guinea pig. ( Ayar, A; Bildirici, I; Celik, H; Cikim, G; Ozercan, I; Simsek, M; Tug, N, 2002) |
| "To investigate whether melatonin reduces the susceptibility of the fetal rat brain to oxidative damage of lipids and DNA, we created a model of fetal ischemia/reperfusion using rats at day 19 of pregnancy." | 3.70 | Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999) |
| "To study the protective effect of melatonin against neuronal injury and the possible roles of alteration in the expression of bcl-2 and bax following brain ischemia." | 3.70 | Protective effect of melatonin on injuried cerebral neurons is associated with bcl-2 protein over-expression. ( Li, XJ; Ling, X; Lu, SD; Sun, FY; Zhang, LM, 1999) |
| "Ischemic reperfusion injury (IRI) causes cellular damage and dysfunction." | 3.11 | Effect of Preoperative Administration of Oral Melatonin on Pneumatic Tourniquet-Induced Ischemia-Reperfusion Injury in Orthopedic Surgery of Lower Extremities: A Randomized Clinical Trial. ( Bagheri, N; Jouybar, R; Khademi, S; Razmjooie, S, 2022) |
| "Melatonin was associated with improvement in renal transplantation, since the serum level of neutrophil gelatinase-associated lipocalin, as a renal functional marker, significantly decreased (P < ." | 2.90 | The effect of oral melatonin on renal ischemia-reperfusion injury in transplant patients: A double-blind, randomized controlled trial. ( Alirezaei, A; Argani, H; Dastmalchi, S; Ghorbanihaghjo, A; Haiaty, S; Hosseini, L; Jabarpour, M; Nazari Soltan Ahmad, S; Panah, F; Rashtchizadeh, N; Rezaeian, R; Sanajou, D, 2019) |
| "While we focus on hemorrhagic shock, many of the described treatments may be used in other situations of hypoxia or ischemia/reperfusion injury." | 2.58 | Hibernation-Based Approaches in the Treatment of Hemorrhagic Shock. ( Beilman, GJ; Lusczek, ER; Wolf, A, 2018) |
| "Melatonin is a powerful endogenous antioxidant produced by the pineal gland and a variety of other because of its efficacy in organs; melatonin has been investigated to improve the outcome of organ transplantation by reducing ischemia-reperfusion injury and due to its synergic effect with organ preservation fluids." | 2.53 | Melatonin role preventing steatohepatitis and improving liver transplantation results. ( Alatorre-Jiménez, MA; Esteban-Zubero, E; García, JJ; García-Gil, FA; López-Pingarrón, L; Ramírez, JM; Reiter, RJ; Tan, DX, 2016) |
| "Melatonin has proven to be a potentially useful therapeutic tool in the reduction of graft rejection." | 2.53 | Potential benefits of melatonin in organ transplantation: a review. ( Alatorre-Jiménez, MA; Esteban-Zubero, E; García, JJ; García-Gil, FA; Iñigo-Gil, P; López-Pingarrón, L; Reiter, RJ; Tan, DX, 2016) |
| "Renal ischemia reperfusion injury (IRI) contributes to the development of acute kidney injury (AKI)." | 2.52 | Novel role of microRNAs in renal ischemia reperfusion injury. ( Banaei, S, 2015) |
| "Melatonin was demonstrated to be involved in the regulation of whole body glucose homeostasis via its effects on pancreatic insulin secretion and may thus indirectly affect myocardial substrate metabolism in a circadian manner." | 2.49 | Cardioprotective effect of melatonin against ischaemia/reperfusion damage. ( Huisamen, B; Lochner, A; Nduhirabandi, F, 2013) |
| "Melatonin is a widely distributed and important signal molecule that occurs in unicellular organisms, plants, and fungi in addition to animals and humans." | 2.45 | Chapter 16: Melatonin and nerve regeneration. ( Kaplan, S; Odaci, E, 2009) |
| " Special attention has been paid to the advantageous characteristics of melatonin as a neuroprotective drug: bioavailability into brain cells and cellular organelles targeted by morpho-functional derangement; effectiveness in exerting several neuroprotective actions, which can be amplified and prolonged by its metabolites, through direct and indirect antioxidant activity; prevention and reversal of mitochondrial malfunction, reducing inflammation, derangement of cytoskeleton organization, and pro-apoptotic cell signaling; lack of interference with thrombolytic and neuroprotective actions of other drugs; and an adequate safety profile." | 2.44 | Melatonin and ischemia-reperfusion injury of the brain. ( Cervantes, M; Letechipía-Vallejo, G; Moralí, G, 2008) |
| "Melatonin has been shown to be effective in arresting neurodegenerative phenomena seen in experimental models of Alzheimer's disease, Parkinsonism and ischemic stroke." | 2.43 | Role of melatonin in neurodegenerative diseases. ( Cardinali, DP; Esquifino, AI; Hardeland, R; Maestroni, GJ; Pandi-Perumal, SR; Srinivasan, V, 2005) |
| "Melatonin is a potent free radical scavenger and an indirect antioxidant." | 2.42 | The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion. ( Cheung, RT, 2003) |
| "Treatment with melatonin has been shown to prevent in vivo the delayed vascular decompensation and the cellular energetic failure associated with shock, inflammation and ischemia/reperfusion injury." | 2.41 | Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. ( Cuzzocrea, S; Reiter, RJ, 2001) |
| "Obesity is well-established as a common comorbidity in ischemic stroke." | 1.91 | Melatonin modulates the aggravation of pyroptosis, necroptosis, and neuroinflammation following cerebral ischemia and reperfusion injury in obese rats. ( Govitrapong, P; Sengking, J; Tocharus, C; Tocharus, J; Yawoot, N, 2023) |
| "Melatonin treatment led to a reduced activity of Rac1, which was responsible for Foxo3a downregulation and decreased cell injury in OGD/R-exposed H9c2 cells." | 1.72 | Melatonin protects H9c2 cardiomyoblasts from oxygen-glucose deprivation and reperfusion-induced injury by inhibiting Rac1/JNK/Foxo3a/Bim signaling pathway. ( Jian, Y; Ni, B; Pan, C; Wang, M; Wang, Y; Zhang, X, 2022) |
| "Melatonin (MT) is an indoleamine hormone that can counteract ischemia‑induced organ injury through its antioxidant effects." | 1.62 | Exogenous melatonin alleviates hemorrhagic shock‑induced hepatic ischemic injury in rats by inhibiting the NF‑κB/IκBα signaling pathway. ( Cai, QQ; Li, HW; Wu, XL; Yang, ZH; Ying, P, 2021) |
| "Melatonin has been reported to alleviate I/R injury by regulating mitophagy and mitochondrial dynamics." | 1.62 | Melatonin postconditioning ameliorates anoxia/reoxygenation injury by regulating mitophagy and mitochondrial dynamics in a SIRT3-dependent manner. ( Bai, Y; Gao, Y; Lin, D; Ma, J; Wang, Z; Yang, Y, 2021) |
| "Diabetic patients are more vulnerable to cerebral ischemia-reperfusion (CIR) injury and have a worse prognosis and higher mortality after ischemic stroke than non-diabetic counterparts." | 1.62 | Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway. ( Cao, Q; Gao, W; Li, B; Liu, L; Xia, Z; Zhao, B, 2021) |
| "CONCLUSIONS EA could alleviate the lung injury induced by limb ischemia-reperfusion by promoting the secretion of melatonin, while having no effect on the expression of melatonin receptor in lung tissues." | 1.56 | The Role of Melatonin in Electroacupuncture Alleviating Lung Injury Induced by Limb Ischemia-Reperfusion in Rabbits. ( Dong, SA; Gong, LR; Kan, YX; Yu, JB, 2020) |
| "Melatonin has anti-inflammatory, anti-oxidative and anti-apoptotic effects against various diseases." | 1.56 | Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion. ( Bai, YP; Chen, Y; Feng, JG; Jia, J; Liu, KX; Yang, B; Zhang, LY; Zhou, J, 2020) |
| "Melatonin treatment significantly decreased infarct volume and cerebral apoptosis; mitigated endoplasmic reticulum stress and mitochondrial dysfunction; and inhibited CI/R injury-induced oxidative/nitrative stress and nuclear factor-κB activation, which was eradicated in RORα-deficient mice." | 1.56 | The circadian nuclear receptor RORα negatively regulates cerebral ischemia-reperfusion injury and mediates the neuroprotective effects of melatonin. ( Ai, L; Gao, L; Gao, Y; Petersen, L; Pu, J; Qin, Z; Tong, R; Yan, Y; Zang, M; Zhao, Y; Zhong, F; Zhu, C, 2020) |
| "Melatonin treatment activated MFN2-related mitochondrial fusion via suppressing Mst1-Hippo pathway, finally sustaining mitochondrial function and reducing reperfusion-mediated cerebral injury." | 1.51 | Effects of melatonin on acute brain reperfusion stress: role of Hippo signaling pathway and MFN2-related mitochondrial protection. ( Bi, C; Lan, S; Liu, J; Luo, X, 2019) |
| "Melatonin treatment also effectively decreased neuron apoptosis resulting from OGD-induced neuron injury." | 1.48 | Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress. ( Chang, CC; Chen, TY; Huang, SY; Hung, CY; Hung, HY; Lee, EJ; Lin, YW; Tai, SH, 2018) |
| "Melatonin (MT) is a hormone that is principally synthesized in the pineal gland." | 1.42 | Melatonin attenuates intestinal ischemia--reperfusion-induced lung injury in rats by upregulating N-myc downstream-regulated gene 2. ( Du, HY; Jiang, T; Ni, YF; Wang, WC; Yang, B; Zhang, H; Zhang, L; Zhang, WD, 2015) |
| "Melatonin treatment reversed the increase of serum TNF-α levels and histopathological injury in renal tissue after renal IR." | 1.42 | Effects of melatonin on the serum levels of pro-inflammatory cytokines and tissue injury after renal ischemia reperfusion in rats. ( Baba, F; Hekimoglu, A; Oguz, E; Ozbilge, H; Tabur, S; Yerer, MB; Yilmaz, Z, 2015) |
| "Melatonin is a free radical scavenger and broad-spectrum antioxidant with immunomodulatory effects." | 1.42 | Melatonin prevents lung injury induced by hepatic ischemia-reperfusion through anti-inflammatory and anti-apoptosis effects. ( An, H; Jiang, C; Yang, B; Zhang, H; Zhao, D; Zhou, L, 2015) |
| "Melatonin (MLT) is a potent and endogenous anti-oxidant that has beneficial effects in liver I/R injury." | 1.40 | Melatonin inhibits mTOR-dependent autophagy during liver ischemia/reperfusion. ( Cho, HI; Kang, JW; Lee, SM, 2014) |
| "It contributes to the development of acute renal failure." | 1.40 | Effect of a combined treatment with erythropoietin and melatonin on renal ischemia reperfusion injury in male rats. ( Ahmadiasl, N; Alihemati, A; Azimian, E; Banaei, S; Baradaran, B, 2014) |
| "Melatonin has a cellular protective effect in cerebrovascular and neurodegenerative diseases." | 1.40 | The beneficial effect of melatonin in brain endothelial cells against oxygen-glucose deprivation followed by reperfusion-induced injury. ( Kang, SM; Lee, JE; Lee, KM; Lee, WT; Park, KA; Song, J, 2014) |
| "Melatonin pretreatment prior to liver I/R can effectively reduce the pulmonary microvascular permeability and attenuate lipid peroxidation in the lungs." | 1.38 | Protective effect of melatonin on liver ischemia-reperfusion induced pulmonary microvascular injury in rats. ( Chen, CF; Chen, KH; Chiu, MH; Su, CL; Wang, D; Wang, JJ, 2012) |
| "Melatonin pretreatment also protected the liver against I/R injury (P < ." | 1.38 | Liver reperfusion-induced decrease in dynamic compliance and increase in airway resistance are ameliorated by preischemic treatment with melatonin through scavenging hydroxyl radicals in rat lungs. ( Chen, CF; Su, CL; Wang, D; Wang, JJ; Yeh, JH, 2012) |
| "Melatonin pretreatment effectively scavenged oxidants and hydroxyl radicals, protecting cardiac function against liver I/R-induced injury." | 1.38 | Preischemic treatment with melatonin attenuates liver reperfusion-induced impairment of cardiac function. ( Chen, KH; Chen, TH; Wang, JJ, 2012) |
| "Melatonin treatment was able to lower the expression of pro-inflammatory cytokines and pro-apoptotic genes and to improve liver function, as indicated by normalization of plasma AST and ALT levels and by reduction of necrosis and microsteatosis areas." | 1.38 | Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin. ( Bela, T; Cuesta, S; Ibarrola, C; Kireev, RA; Moreno Gonzalez, E; Tresguerres, JA; Vara, E, 2012) |
| "Melatonin or vehicle was given intravenously 10 min prior to reperfusion and 10 min after reperfusion." | 1.37 | Melatonin attenuates I/R-induced mitochondrial dysfunction in skeletal muscle. ( Fang, XH; Khiabani, KT; Stephenson, LL; Wang, WZ; Zamboni, WA; Zhang, X, 2011) |
| "Melatonin was given i." | 1.37 | Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke. ( Baud, O; Biran, V; Charriaut-Marlangue, C; Fau, S; Renolleau, S; Villapol, S, 2011) |
| "Rats were subjected to 60 min of middle cerebral artery occlusion (MCAO) followed by reperfusion." | 1.37 | Pre-treatment of adrenomedullin suppresses cerebral edema caused by transient focal cerebral ischemia in rats detected by magnetic resonance imaging. ( Kondoh, T; Torii, K; Ueta, Y, 2011) |
| "Melatonin treatment significantly reduced the level of serum alanine aminotransferase activity." | 1.37 | Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway. ( Kang, JW; Koh, EJ; Lee, SM, 2011) |
| "Melatonin is a potent scavenger of reactive oxygen species and a strong antioxidant." | 1.37 | Melatonin prevents hepatic injury-induced decrease in Akt downstream targets phosphorylations. ( Koh, PO, 2011) |
| "Treatment with melatonin significantly reduced hepatic damage, being oral administration more effective." | 1.37 | [Effect of pretreatment with melatonin on the oxidative and inflammatory damage induced by hepatic ischemia/reperfusion in Zucker rats]. ( Hernández, JA, 2011) |
| "Melatonin treatment did not prevent the IR-induced reduction in sperm concentration." | 1.36 | Effect of melatonin on epididymal sperm quality after testicular ischemia/reperfusion in rats. ( Aral, F; Baba, F; Hekimoglu, A; Kurcer, Z; Sahna, E, 2010) |
| "Melatonin treatment also maintained AANAT immunoreactivity and its protein levels in the CA1 region after ischemia/reperfusion." | 1.36 | Arylalkylamine N-acetyltransferase (AANAT) is expressed in astrocytes and melatonin treatment maintains AANAT in the gerbil hippocampus induced by transient cerebral ischemia. ( Choi, JH; Hwang, IK; Kim, YM; Kwon, YG; Lee, CH; Park, JH; Park, OK; Won, MH; Yoo, KY, 2010) |
| "Melatonin is a potent free radical scavenger and a strong antioxidant." | 1.36 | Proteomic identification of proteins differentially expressed by melatonin in hepatic ischemia-reperfusion injury. ( Cho, EH; Koh, PO, 2010) |
| "(2)Melatonin treatment alleviated total hepatic I/R-induced lung injury." | 1.35 | [Total hepatic ischemia-reperfusion-induced lung injury in rats and protective effects of melatonin]. ( Jia, R; Jiang, CL; Yang, BX; Zhao, D, 2008) |
| "Melatonin treatment reversed all these oxidant and antioxidant parameters to control values as well as serum liver enzymes." | 1.35 | Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus. ( Fadillioglu, E; Gursul, C; Iraz, M; Kurcer, Z; Parlakpinar, H, 2008) |
| "Melatonin is a potent scavenger of reactive oxygen and nitrogen species." | 1.35 | Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation. ( Bruns, H; Büchler, MW; Gross, ML; Hoffmann, K; Li, Z; Mohr, E; Nickkholgh, A; Schemmer, P; Yi, X; Zorn, M, 2009) |
| "Both Melatonin and 1400W were efficient in ameliorating experimental I/R injury of the kidneys." | 1.35 | Comparison of the efficacy of melatonin and 1400W on renal ischemia/reperfusion injury: a role for inhibiting iNOS. ( Akgul, EO; Cayci, T; Cetiner, S; Ersoz, N; Guven, A; Korkmaz, A; Oztas, E; Turk, E; Uysal, B, 2009) |
| "Melatonin treatment decreased lipid and protein oxidation and ameloriated histopathologic alterations induced by IR without any change in proinflammatory cytokine levels." | 1.35 | Effect of melatonin on testicular ischemia/reperfusion injury in rats: is this effect related to the proinflammatory cytokines? ( Aksoy, N; Baba, F; Celik, N; Kurcer, Z; Oguz, E; Ozbilge, H, 2008) |
| "The melatonin-treated rats showed markedly fewer apoptotic (TUNEL positive) cells and DNA fragmentation than did the I/R rats." | 1.35 | Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver. ( Kim, SH; Lee, SM, 2008) |
| "Melatonin is a potent scavenger of ROS." | 1.35 | Melatonin protects from hepatic reperfusion injury through inhibition of IKK and JNK pathways and modification of cell proliferation. ( Büchler, MW; Hoffmann, K; Kern, M; Liang, R; Nickkholgh, A; Schemmer, P; Schneider, H; Sobirey, M; Zorn, M, 2009) |
| "Melatonin treatment also resulted with MDA formation (P=0." | 1.34 | The effects of prophylactic zinc and melatonin application on experimental spinal cord ischemia-reperfusion injury in rabbits: experimental study. ( Abuşoglu, S; Avunduk, MC; Baysefer, A; Ciçek, O; Kalkan, E; Kalkan, SS; Unlü, A, 2007) |
| "Melatonin treatment reduced the biochemical indices without any change in the cytokine levels and ameliorated histopathologic alterations induced by IR." | 1.34 | Melatonin protects from ischemia/reperfusion-induced renal injury in rats: this effect is not mediated by proinflammatory cytokines. ( Aksoy, N; Baba, F; Cakir, H; Celik, H; Gezen, MR; Kurcer, Z; Oguz, E; Ozbilge, H, 2007) |
| "Melatonin in particular was effective to reverse hot ischemia of kidney by its antioxidant effects." | 1.34 | The protective effects of melatonin and vitamin E against renal ischemia-reperfusion injury in rats. ( Aktoz, T; Alagol, B; Atakan, IH; Aydogdu, N; Huseyinova, G; Yalcin, O, 2007) |
| "The purpose of this study was to investigate the effects of chronic administration of melatonin on renal ischemia/reperfusion (IR) injury in streptozotocin (STZ)-induced diabetic rats." | 1.34 | Protective effects of chronic melatonin treatment against renal ischemia/reperfusion injury in streptozotocin-induced diabetic rats. ( Baba, F; Fadillioglu, E; Gül, M; Iraz, M; Kurcer, Z; Parlakpinar, H; Tasdemir, S; Vardi, N, 2007) |
| "Melatonin is a well-known antioxidant and free radical scavenger." | 1.33 | Protective effects of melatonin on myocardial ischemia/reperfusion induced infarct size and oxidative changes. ( Acet, A; Parlakpinar, H; Sahna, E; Turkoz, Y, 2005) |
| "Melatonin has been considered as an antioxidant that prevents injuries resulted from I/R in various tissues." | 1.33 | Protective effect of melatonin on contractile activity and oxidative injury induced by ischemia and reperfusion of rat ileum. ( Aktas, RG; Altaner, S; Arslan, SO; Ozacmak, VH; Sayan, H, 2005) |
| "Melatonin has a protective effect against I/R injury in skeletal muscle and may reduce the incidence of compartment syndrome, especially after acute or chronic peripheral arterial occlusions." | 1.33 | Melatonin protects against ischemia/reperfusion injury in skeletal muscle. ( Ercan, F; Erkanli, G; Erkanli, K; Kayalar, N; Kirali, K; Sener, G, 2005) |
| "Melatonin has reversed the inhibition of contractility caused by I/R injury in part." | 1.33 | L-Arginine and melatonin interaction in rat intestinal ischemia--reperfusion. ( Arslan, SO; Gelir, E; Ozacmak, VH; Sayan, H, 2005) |
| "Melatonin was intraperitoneally administered before or/and after IR injury." | 1.33 | Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas. ( Briceño, J; Collado, JA; Cruz, A; Montilla, P; Muñoz-Casares, FC; Muñoz-Castañeda, JR; Muntané, J; Ortega, R; Padillo, FJ; Pera, C; Túnez, I, 2006) |
| "Melatonin or vehicle was administered 1 h before flap elevation and was continued for 6 days after ischemia." | 1.33 | The protective effect of melatonin on ischemia-reperfusion injury in the groin (inferior epigastric) flap model in rats. ( Aydogan, H; Bay-Karabulut, A; Celik, M; Gurlek, A; Parlakpinar, H, 2006) |
| "Melatonin treatment improved the penumbral CBF in the wild-type mice." | 1.33 | Melatonin reduces infarction volume in a photothrombotic stroke model in the wild-type but not cyclooxygenase-1-gene knockout mice. ( Cheung, RT; Huang, L; Li, G; Liu, S; Zou, LY, 2006) |
| "Melatonin treatment significantly reduced superoxide generation in arterial walls and improved cell viability in cremaster muscles." | 1.33 | Melatonin reduces ischemia/reperfusion-induced superoxide generation in arterial wall and cell death in skeletal muscle. ( Fang, XH; Khiabani, KT; Stephenson, LL; Wang, WZ; Zamboni, WA, 2006) |
| "Melatonin treatment in I/R rats reversed these changes (P < 0." | 1.32 | Melatonin ameliorates oxidative organ damage induced by acute intra-abdominal compartment syndrome in rats. ( Kaçmaz, A; Ozkan, S; Sener, G; Tilki, M; User, Y; Yeğen, BC, 2003) |
| "Melatonin was administered either 10 min before aortic occlusion or 10 min after the clamp was removed." | 1.32 | Protective effect of melatonin on experimental spinal cord ischemia. ( Aydemir, S; Colak, A; Erten, SF; Kocak, A; Ozdemir, I; Reeder, BS, 2003) |
| "Melatonin and PGE1 were found to be effective in reducing the hepatic ischaemia reperfusion damage in rats." | 1.32 | The effects of melatonin and prostaglandin E1 analogue on experimental hepatic ischaemia reperfusion damage. ( Akkus, MA; Aygen, E; Bülbüller, N; Cetinkaya, Z; Cifter, C; Dogru, O; Ilhan, YS, 2003) |
| "Melatonin treatment diminished the loss of neurons and decreased the infarct volume as compared with untreated MCAO rats." | 1.32 | Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin. ( Andrabi, SA; Horn, TF; Sayeed, I; Siemen, D; Wolf, G, 2004) |
| "Melatonin is a hormone with antioxidant properties." | 1.32 | Melatonin does not prevent the protection of ischemic preconditioning in vivo despite its antioxidant effect against oxidative stress. ( Andreadou, I; Bofilis, E; Constantinou, M; Iliodromitis, EK; Kremastinos, DT; Mikros, E; Tsantili-Kakoulidou, A; Zoga, A, 2004) |
| "Melatonin and saline were injected intraperitoneally (10 mg/kg) 30 min before detorsion to the I/R plus melatonin group and I/R plus saline group respectively." | 1.32 | Melatonin reduces torsion-detorsion injury in rat ovary: biochemical and histopathologic evaluation. ( Celik, O; Cigremis, Y; Hascalik, M; Hascalik, S; Mizrak, B; Turkoz, Y; Yologlu, S, 2004) |
| "Melatonin treatment reversed the I/R-induced increase and decrease in MDA and SOD levels, respectively." | 1.32 | Beneficial effects of melatonin on reperfusion injury in rat sciatic nerve. ( Aktas, RG; Arslan, SO; Coskun, O; Ozacmak, VH; Ozen, OA; Sayan, H; Sezen, SC, 2004) |
| "Melatonin treatment reversed ischemia/reperfusion-induced reduction in RCI (2." | 1.32 | Maternally administered melatonin protects against ischemia and reperfusion-induced oxidative mitochondrial damage in premature fetal rat brain. ( Fukaya, T; Ikenoue, N; Shinohara, K; Wakatsuki, A; Watanabe, K; Yokota, K, 2004) |
| "Malondialdehyde (MDA) levels were assayed as an index of lipid peroxidation reflecting free radical reaction in the intestine." | 1.31 | The role of melatonin in prevention of intestinal ischemia-reperfusion injury in rats. ( Demirbağ, M; Kazez, A; Ozercan, IH; Sağlam, M; Ustündağ, B, 2000) |
| "Melatonin treatment increased survival and reduced hyperactivity linked to neurodegeneration induced by cerebral ischemia and reperfusion." | 1.31 | Protective effects of melatonin in ischemic brain injury. ( Barberi, I; Caputi, AP; Cordaro, S; Costantino, G; Cuzzocrea, S; De Sarro, A; Fulia, F; Gitto, E; Mazzon, E; Serraino, I, 2000) |
| "Melatonin treatment reversed the ischemia/reperfusion-induced reductions in the RCI (2." | 1.31 | Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain. ( Fukaya, T; Ikenoue, N; Okatani, Y; Shinohara, K; Wakatsuki, A, 2001) |
| "Melatonin could be useful in treating preeclampsia and possibly other clinical states involving excess free radical production, such as fetal growth restriction and fetal hypoxia." | 1.31 | Melatonin protects against oxidative mitochondrial damage induced in rat placenta by ischemia and reperfusion. ( Fukaya, T; Okatani, Y; Shinohara, K; Taniguchi, K; Wakatsuki, A, 2001) |
| "Melatonin treatment in the ischemia-reperfusion group reversed these responses." | 1.31 | The effects of melatonin on ischemia-reperfusion induced changes in rat corpus cavernosum. ( Alican, I; Dülger, GA; Paskaloğlu, K; Sehirli, AO; Sener, G, 2002) |
| "Melatonin was either infused during both the ischemia and reperfusion periods or only late in the ischemia period and throughout reperfusion." | 1.30 | Ischemia/reperfusion-induced arrhythmias in the isolated rat heart: prevention by melatonin. ( El-Sokkary, GH; Kim, SJ; Manchester, LC; Qi, W; Reiter, RJ; Tan, DX, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (4.08) | 18.2507 |
| 2000's | 97 (39.59) | 29.6817 |
| 2010's | 91 (37.14) | 24.3611 |
| 2020's | 47 (19.18) | 2.80 |
| Authors | Studies |
|---|---|
| Bi, W | 1 |
| Bi, Y | 1 |
| Xue, P | 1 |
| Zhang, Y | 6 |
| Gao, X | 3 |
| Wang, Z | 7 |
| Li, M | 1 |
| Baudy-Floc'h, M | 1 |
| Ngerebara, N | 1 |
| Gibson, KM | 1 |
| Bi, L | 1 |
| Tenti, G | 1 |
| Parada, E | 1 |
| León, R | 1 |
| Egea, J | 1 |
| Martínez-Revelles, S | 1 |
| Briones, AM | 1 |
| Sridharan, V | 1 |
| López, MG | 1 |
| Ramos, MT | 1 |
| Menéndez, JC | 1 |
| Sarı, E | 1 |
| Dilli, D | 1 |
| Taşoğlu, İ | 1 |
| Akduman, H | 1 |
| Yumuşak, N | 1 |
| Tümer, NB | 1 |
| Salar, S | 1 |
| Liu, L | 6 |
| Cao, Q | 2 |
| Gao, W | 2 |
| Li, BY | 1 |
| Zeng, C | 1 |
| Xia, Z | 3 |
| Zhao, B | 3 |
| Yawoot, N | 2 |
| Sengking, J | 2 |
| Wicha, P | 1 |
| Govitrapong, P | 2 |
| Tocharus, C | 2 |
| Tocharus, J | 2 |
| Wang, Y | 6 |
| Jian, Y | 1 |
| Zhang, X | 4 |
| Ni, B | 1 |
| Wang, M | 3 |
| Pan, C | 1 |
| Chen, X | 3 |
| Shen, X | 1 |
| Lai, J | 1 |
| Yao, Z | 1 |
| Peng, X | 1 |
| Wu, L | 1 |
| Ou, Y | 1 |
| Wu, H | 1 |
| Zhu, H | 3 |
| Deng, Y | 1 |
| Zhong, XY | 2 |
| Ruan, S | 3 |
| Wang, F | 3 |
| Chen, B | 3 |
| Luo, J | 2 |
| Wang, YX | 2 |
| Liang, H | 3 |
| Jouybar, R | 1 |
| Khademi, S | 1 |
| Razmjooie, S | 1 |
| Bagheri, N | 1 |
| Zhong, X | 1 |
| Li, Z | 5 |
| Lin, R | 1 |
| Tao, J | 1 |
| Yuan, X | 1 |
| Xi, Z | 1 |
| Yu, B | 1 |
| Peña-Mercado, E | 1 |
| Garcia-Lorenzana, M | 1 |
| Huerta-Yepez, S | 1 |
| Cruz-Ledesma, A | 1 |
| Beltran-Vargas, NE | 1 |
| Huang, YB | 1 |
| Jiang, L | 2 |
| Liu, XQ | 1 |
| Wang, X | 7 |
| Gao, L | 2 |
| Zeng, HX | 1 |
| Zhu, W | 1 |
| Hu, XR | 1 |
| Wu, YG | 1 |
| Zheng, Y | 1 |
| Gao, N | 1 |
| Zhang, W | 1 |
| Ma, R | 1 |
| Chi, F | 1 |
| Gao, Z | 1 |
| Cong, N | 1 |
| Missawi, O | 3 |
| Jeddou, IB | 3 |
| Venditti, M | 3 |
| Zitouni, N | 3 |
| Zaouali, MA | 7 |
| Abdennebi, HB | 4 |
| Messaoudi, I | 3 |
| Reiter, RJ | 20 |
| Minucci, S | 3 |
| Banni, M | 3 |
| Ding, Y | 1 |
| Dai, JY | 1 |
| Jia, H | 1 |
| Fu, HL | 1 |
| Mokhtari, B | 1 |
| Hosseini, L | 2 |
| Høilund-Carlsen, PF | 1 |
| Salehinasab, R | 1 |
| Rajabi, M | 1 |
| Badalzadeh, R | 1 |
| Yan, NW | 1 |
| Liu, JJ | 1 |
| Song, Z | 2 |
| Yan, C | 1 |
| Zhan, Y | 1 |
| Wang, Q | 1 |
| Jiang, T | 2 |
| Yilmaz, U | 1 |
| Tanbek, K | 1 |
| Gul, S | 1 |
| Gul, M | 2 |
| Koc, A | 1 |
| Sandal, S | 1 |
| Xu, Q | 1 |
| Cheung, RTF | 1 |
| Gong, P | 1 |
| Zhang, M | 1 |
| Li, C | 3 |
| Xiao, P | 1 |
| Yu, M | 1 |
| An, L | 1 |
| Bi, F | 1 |
| Song, X | 1 |
| Azedi, F | 1 |
| Mehrpour, M | 1 |
| Talebi, S | 1 |
| Zendedel, A | 1 |
| Kazemnejad, S | 1 |
| Mousavizadeh, K | 1 |
| Beyer, C | 1 |
| Zarnani, AH | 1 |
| Joghataei, MT | 1 |
| Panah, F | 1 |
| Ghorbanihaghjo, A | 1 |
| Argani, H | 1 |
| Haiaty, S | 1 |
| Rashtchizadeh, N | 1 |
| Dastmalchi, S | 1 |
| Rezaeian, R | 1 |
| Alirezaei, A | 1 |
| Jabarpour, M | 1 |
| Nazari Soltan Ahmad, S | 1 |
| Sanajou, D | 1 |
| Chen, H | 1 |
| Jin, J | 1 |
| Tang, Z | 1 |
| Yin, P | 1 |
| Zhong, D | 1 |
| Li, G | 2 |
| Ostróżka-Cieślik, A | 2 |
| Dolińska, B | 2 |
| Dong, SA | 1 |
| Gong, LR | 1 |
| Yu, JB | 1 |
| Kan, YX | 1 |
| Yang, B | 4 |
| Zhang, LY | 1 |
| Chen, Y | 6 |
| Bai, YP | 1 |
| Jia, J | 1 |
| Feng, JG | 1 |
| Liu, KX | 1 |
| Zhou, J | 2 |
| Zang, M | 1 |
| Zhao, Y | 3 |
| Zhong, F | 1 |
| Qin, Z | 1 |
| Tong, R | 1 |
| Ai, L | 1 |
| Petersen, L | 1 |
| Yan, Y | 1 |
| Gao, Y | 4 |
| Zhu, C | 2 |
| Pu, J | 1 |
| Yang, J | 2 |
| Liu, H | 2 |
| Han, S | 1 |
| Fu, Z | 1 |
| Wang, J | 8 |
| Wang, L | 4 |
| Zahran, R | 1 |
| Ghozy, A | 1 |
| Elkholy, SS | 1 |
| El-Taweel, F | 1 |
| El-Magd, MA | 1 |
| Zang, LE | 1 |
| Cui, JW | 1 |
| Zhang, MY | 1 |
| Ma, X | 1 |
| Wei, LL | 1 |
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 1 |
| Zhang, J | 3 |
| Shen, S | 1 |
| Zhang, B | 2 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Xue, L | 1 |
| Yan, X | 3 |
| Huang, S | 1 |
| Li, Y | 7 |
| Xu, T | 1 |
| Ji, F | 1 |
| Ming, F | 1 |
| Cheng, J | 1 |
| Zhao, H | 1 |
| Hong, S | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Wei, J | 1 |
| Wu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
| Jhunjhunwala, R | 1 |
| McIntyre, RC | 1 |
| Moore, PK | 1 |
| Hajizadeh, N | 1 |
| Talmor, DS | 1 |
| Sauaia, A | 1 |
| Yaffe, MB | 1 |
| Liu, C | 4 |
| Lin, Y | 1 |
| Dong, Y | 1 |
| Wu, Y | 1 |
| Bao, Y | 1 |
| Yan, H | 2 |
| Ma, J | 3 |
| Fernández-Cuadros, ME | 1 |
| Albaladejo-Florín, MJ | 1 |
| Álava-Rabasa, S | 1 |
| Usandizaga-Elio, I | 1 |
| Martinez-Quintanilla Jimenez, D | 1 |
| Peña-Lora, D | 1 |
| Neira-Borrajo, I | 1 |
| López-Muñoz, MJ | 1 |
| Rodríguez-de-Cía, J | 1 |
| Pérez-Moro, OS | 1 |
| Abdallah, M | 1 |
| Alsaleh, H | 1 |
| Baradwan, A | 1 |
| Alfawares, R | 1 |
| Alobaid, A | 1 |
| Rasheed, A | 1 |
| Soliman, I | 1 |
| Wendel Garcia, PD | 1 |
| Fumeaux, T | 1 |
| Guerci, P | 1 |
| Heuberger, DM | 1 |
| Montomoli, J | 2 |
| Roche-Campo, F | 1 |
| Schuepbach, RA | 1 |
| Hilty, MP | 1 |
| Poloni, TE | 1 |
| Carlos, AF | 1 |
| Cairati, M | 1 |
| Cutaia, C | 1 |
| Medici, V | 1 |
| Marelli, E | 1 |
| Ferrari, D | 1 |
| Galli, A | 1 |
| Bognetti, P | 1 |
| Davin, A | 1 |
| Cirrincione, A | 1 |
| Ceretti, A | 1 |
| Cereda, C | 1 |
| Ceroni, M | 1 |
| Tronconi, L | 1 |
| Vitali, S | 1 |
| Guaita, A | 1 |
| Leeds, JS | 1 |
| Raviprakash, V | 1 |
| Jacques, T | 1 |
| Scanlon, N | 1 |
| Cundall, J | 1 |
| Leeds, CM | 1 |
| Riva, A | 1 |
| Gray, EH | 1 |
| Azarian, S | 1 |
| Zamalloa, A | 1 |
| McPhail, MJW | 1 |
| Vincent, RP | 1 |
| Williams, R | 1 |
| Chokshi, S | 1 |
| Patel, VC | 1 |
| Edwards, LA | 1 |
| Alqarawi, W | 1 |
| Birnie, DH | 1 |
| Golian, M | 1 |
| Nair, GM | 1 |
| Nery, PB | 1 |
| Klein, A | 1 |
| Davis, DR | 1 |
| Sadek, MM | 1 |
| Neilipovitz, D | 1 |
| Johnson, CB | 1 |
| Green, MS | 1 |
| Redpath, C | 1 |
| Miller, DC | 1 |
| Beamer, P | 1 |
| Billheimer, D | 1 |
| Subbian, V | 1 |
| Sorooshian, A | 1 |
| Campbell, BS | 1 |
| Mosier, JM | 1 |
| Novaretti, JV | 1 |
| Astur, DC | 1 |
| Cavalcante, ELB | 1 |
| Kaleka, CC | 1 |
| Amaro, JT | 1 |
| Cohen, M | 1 |
| Huang, W | 1 |
| Li, T | 2 |
| Ling, Y | 1 |
| Qian, ZP | 1 |
| Zhang, YY | 1 |
| Huang, D | 1 |
| Xu, SB | 1 |
| Liu, XH | 1 |
| Xia, L | 1 |
| Yang, Y | 7 |
| Lu, SH | 1 |
| Lu, HZ | 1 |
| Zhang, R | 2 |
| Ma, JX | 1 |
| Tang, S | 1 |
| Li, CM | 1 |
| Wan, J | 1 |
| Wang, JF | 1 |
| Ma, JQ | 1 |
| Luo, JJ | 1 |
| Chen, HY | 6 |
| Mi, SL | 1 |
| Chen, SY | 3 |
| Su, YG | 1 |
| Ge, JB | 1 |
| Milheiro, SA | 1 |
| Gonçalves, J | 1 |
| Lopes, RMRM | 1 |
| Madureira, M | 1 |
| Lobo, L | 1 |
| Lopes, A | 1 |
| Nogueira, F | 1 |
| Fontinha, D | 1 |
| Prudêncio, M | 1 |
| M Piedade, MF | 1 |
| Pinto, SN | 1 |
| Florindo, PR | 1 |
| Moreira, R | 1 |
| Castillo-Lora, J | 1 |
| Delley, MF | 1 |
| Laga, SM | 1 |
| Mayer, JM | 1 |
| Sutjarit, N | 1 |
| Thongon, N | 1 |
| Weerachayaphorn, J | 1 |
| Piyachaturawat, P | 1 |
| Suksamrarn, A | 1 |
| Suksen, K | 1 |
| Papachristou, DJ | 1 |
| Blair, HC | 1 |
| Hu, Y | 2 |
| Shen, P | 1 |
| Zeng, N | 1 |
| Yan, D | 1 |
| Cui, L | 1 |
| Yang, K | 2 |
| Zhai, C | 1 |
| Yang, M | 1 |
| Lao, X | 1 |
| Sun, J | 1 |
| Ma, N | 1 |
| Wang, S | 1 |
| Ye, W | 2 |
| Guo, P | 1 |
| Rahimi, S | 1 |
| Singh, MP | 1 |
| Gupta, J | 1 |
| Nakanishi, I | 1 |
| Ohkubo, K | 1 |
| Shoji, Y | 1 |
| Fujitaka, Y | 1 |
| Shimoda, K | 1 |
| Matsumoto, KI | 1 |
| Fukuhara, K | 1 |
| Hamada, H | 1 |
| van der Boom, T | 1 |
| Gruppen, EG | 1 |
| Lefrandt, JD | 1 |
| Connelly, MA | 1 |
| Links, TP | 1 |
| Dullaart, RPF | 1 |
| Berry, JD | 1 |
| Bedlack, R | 1 |
| Mathews, D | 1 |
| Agnese, W | 1 |
| Apple, S | 1 |
| Meloncelli, S | 1 |
| Divizia, M | 1 |
| Germani, G | 1 |
| Adefegha, SA | 1 |
| Bottari, NB | 1 |
| Leal, DB | 1 |
| de Andrade, CM | 1 |
| Schetinger, MR | 1 |
| Martínez-Velasco, A | 1 |
| Perez-Ortiz, AC | 1 |
| Antonio-Aguirre, B | 1 |
| Martínez-Villaseñor, L | 1 |
| Lira-Romero, E | 1 |
| Palacio-Pastrana, C | 1 |
| Zenteno, JC | 1 |
| Ramirez, I | 1 |
| Zepeda-Palacio, C | 1 |
| Mendoza-Velásquez, C | 1 |
| Camacho-Ordóñez, A | 1 |
| Ortiz Bibriesca, DM | 1 |
| Estrada-Mena, FJ | 1 |
| Martin, BL | 1 |
| Thompson, LC | 1 |
| Kim, YH | 2 |
| Snow, SJ | 1 |
| Schladweiler, MC | 1 |
| Phillips, P | 1 |
| Harmon, M | 1 |
| King, C | 1 |
| Richards, J | 1 |
| George, I | 1 |
| Haykal-Coates, N | 1 |
| Gilmour, MI | 1 |
| Kodavanti, UP | 1 |
| Hazari, MS | 1 |
| Farraj, AK | 1 |
| Shen, Z | 1 |
| Zou, Y | 1 |
| Gao, K | 1 |
| Lazar, S | 1 |
| Wurtzel, JGT | 1 |
| Ma, P | 1 |
| Goldfinger, LE | 1 |
| Vukelic, M | 1 |
| Laloo, A | 1 |
| Kyttaris, VC | 1 |
| Chen, R | 1 |
| Chen, J | 3 |
| Xun, J | 1 |
| Hu, Z | 1 |
| Huang, Q | 2 |
| Steinhart, C | 1 |
| Shen, Y | 1 |
| Lu, H | 1 |
| Mansuri, A | 1 |
| Lokhande, K | 1 |
| Kore, S | 1 |
| Gaikwad, S | 1 |
| Nawani, N | 1 |
| Swamy, KV | 1 |
| Junnarkar, M | 1 |
| Pawar, S | 1 |
| Shaheen, MY | 1 |
| Basudan, AM | 1 |
| Niazy, AA | 1 |
| van den Beucken, JJJP | 1 |
| Jansen, JA | 1 |
| Alghamdi, HS | 1 |
| Gao, Q | 2 |
| Guo, X | 1 |
| Cao, Y | 2 |
| Jia, X | 1 |
| Xu, S | 1 |
| Lu, C | 3 |
| Melku, M | 1 |
| Abebe, G | 1 |
| Teketel, A | 1 |
| Asrie, F | 1 |
| Yalew, A | 1 |
| Biadgo, B | 1 |
| Kassa, E | 1 |
| Damtie, D | 1 |
| Anlay, DZ | 1 |
| Ahmed, MFE | 1 |
| Ramadan, H | 1 |
| Seinige, D | 1 |
| Kehrenberg, C | 1 |
| Abd El-Wahab, A | 1 |
| Volkmann, N | 1 |
| Kemper, N | 1 |
| Schulz, J | 1 |
| Hu, MY | 1 |
| Wu, YN | 1 |
| McEvoy, MP | 1 |
| Wang, YF | 1 |
| Cong, WL | 1 |
| Liu, LP | 1 |
| Li, XX | 1 |
| Zhou, CL | 1 |
| Chen, WM | 1 |
| Wei, KL | 1 |
| Tung, SY | 1 |
| Shen, CH | 1 |
| Chang, TS | 1 |
| Yen, CW | 1 |
| Hsieh, YY | 1 |
| Chiu, WN | 1 |
| Hu, JH | 1 |
| Lu, SN | 1 |
| Hung, CH | 1 |
| Alakavuklar, MA | 1 |
| Fuqua, C | 1 |
| Luo, KL | 1 |
| Underwood, RS | 1 |
| Greenwald, I | 1 |
| Elashiry, MM | 1 |
| Elashiry, M | 1 |
| Zeitoun, R | 1 |
| Elsayed, R | 1 |
| Tian, F | 2 |
| Saber, SE | 1 |
| Elashry, SH | 1 |
| Tay, FR | 1 |
| Cutler, CW | 1 |
| O'Dowd, A | 1 |
| Maciel, M | 1 |
| Poole, ST | 1 |
| Jobling, MG | 1 |
| Rollenhagen, JE | 1 |
| Woods, CM | 1 |
| Sincock, SA | 1 |
| McVeigh, AL | 1 |
| Gregory, MJ | 1 |
| Maves, RC | 1 |
| Prouty, MG | 1 |
| Holmes, RK | 1 |
| Savarino, SJ | 1 |
| Mor, MK | 1 |
| Palevsky, PM | 1 |
| Kaufman, JS | 1 |
| Thiessen Philbrook, H | 1 |
| Weisbord, SD | 1 |
| Parikh, CR | 1 |
| John, CM | 1 |
| Phillips, NJ | 1 |
| Jarvis, GA | 1 |
| Zhu, Y | 1 |
| Kilburn, S | 1 |
| Kapoor, M | 1 |
| Chaturvedi, S | 1 |
| Shaw, KJ | 1 |
| Chaturvedi, V | 1 |
| Kong, X | 1 |
| Zhang, T | 1 |
| Xiao, H | 1 |
| Feng, X | 2 |
| Tu, H | 1 |
| Feng, J | 1 |
| Sabet, M | 1 |
| Tarazi, Z | 1 |
| Griffith, DC | 1 |
| Nguyen, F | 1 |
| Guan, P | 1 |
| Guerrero, DT | 1 |
| Kolla, V | 1 |
| Naraparaju, K | 1 |
| Perry, LM | 1 |
| Soberman, D | 1 |
| Pressly, BB | 1 |
| Alferiev, IS | 1 |
| Chorny, M | 1 |
| Brodeur, GM | 1 |
| Cheng, YH | 1 |
| Enten, GA | 1 |
| DeSantis, AJ | 1 |
| Gaponenko, V | 1 |
| Majetschak, M | 1 |
| Kim, DY | 1 |
| Choi, MJ | 1 |
| Ko, TK | 1 |
| Lee, NH | 1 |
| Kim, OH | 1 |
| Cheon, HG | 1 |
| Cai, H | 1 |
| Yip, V | 1 |
| Lee, MV | 1 |
| Wong, S | 1 |
| Saad, O | 1 |
| Ma, S | 1 |
| Ljumanovic, N | 1 |
| Khojasteh, SC | 1 |
| Kamath, AV | 1 |
| Shen, BQ | 1 |
| Cuypers, ML | 1 |
| Chanteux, H | 1 |
| Gillent, E | 1 |
| Bonnaillie, P | 1 |
| Saunders, K | 1 |
| Beckers, C | 1 |
| Delatour, C | 1 |
| Dell'Aiera, S | 1 |
| Ungell, AL | 1 |
| Nicolaï, J | 1 |
| Knapp, AK | 1 |
| Chen, A | 1 |
| Griffin-Nolan, RJ | 1 |
| Baur, LE | 1 |
| Carroll, CJW | 1 |
| Gray, JE | 1 |
| Hoffman, AM | 1 |
| Li, X | 5 |
| Post, AK | 1 |
| Slette, IJ | 1 |
| Collins, SL | 1 |
| Luo, Y | 1 |
| Smith, MD | 1 |
| Temitayo, GI | 1 |
| Olawande, B | 1 |
| Emmanuel, YO | 1 |
| Timothy, AT | 1 |
| Kehinde, O | 1 |
| Susan, LF | 1 |
| Ezra, L | 1 |
| Joseph, OO | 1 |
| Lev, S | 1 |
| Desmarini, D | 1 |
| Liuwantara, D | 1 |
| Sorrell, TC | 1 |
| Hawthorne, WJ | 1 |
| Djordjevic, JT | 1 |
| Verso, MG | 1 |
| Costantino, C | 1 |
| Marrella, A | 1 |
| Immordino, P | 1 |
| Vitale, F | 1 |
| Amodio, E | 1 |
| Wang, YD | 1 |
| Yao, WL | 1 |
| Xin, ZM | 1 |
| Han, TT | 1 |
| Wang, ZG | 1 |
| Chen, L | 2 |
| Cai, C | 1 |
| Ba, D | 1 |
| Wen, S | 1 |
| Tian, Q | 1 |
| Lv, W | 1 |
| Cheng, G | 1 |
| Li, N | 1 |
| Yue, XY | 1 |
| Chu, WJ | 1 |
| Chen, Q | 1 |
| Choi, ES | 1 |
| Zhao, X | 3 |
| Zhou, HD | 1 |
| Sun, XF | 1 |
| Sharma, S | 2 |
| Chhoker, S | 1 |
| Xie, C | 1 |
| Ong, EWY | 1 |
| Tan, ZK | 1 |
| Evans, S | 1 |
| Weinheimer, CJ | 1 |
| Kovacs, A | 1 |
| Williams, JW | 1 |
| Randolph, GJ | 1 |
| Jiang, W | 1 |
| Barger, PM | 1 |
| Mann, DL | 1 |
| Liu, J | 3 |
| Huang, Y | 1 |
| Kong, L | 1 |
| Yu, X | 1 |
| Feng, B | 1 |
| Liu, D | 1 |
| Mendes, GC | 1 |
| Yuan, P | 1 |
| Ge, D | 1 |
| Wang, WM | 1 |
| Fontes, EPB | 1 |
| Li, P | 1 |
| Shan, L | 1 |
| He, P | 1 |
| Katoh, T | 1 |
| Sengoku, T | 1 |
| Hirata, K | 1 |
| Ogata, K | 1 |
| Suga, H | 1 |
| Shun, C | 1 |
| Yong-Yi, J | 1 |
| Mei-Li, C | 1 |
| Shi-Li, L | 1 |
| Jian-Bo, Z | 1 |
| Dan-Li, W | 1 |
| Zhi-Min, G | 1 |
| Ibrahim, AM | 1 |
| Zakhary, SY | 1 |
| Amin, SAW | 1 |
| Ugurlu, M | 1 |
| Fornari, VJ | 1 |
| Hartmann, MSM | 1 |
| Vanni, JR | 1 |
| Rodriguez, R | 1 |
| Langaro, MC | 1 |
| Pelepenko, LE | 1 |
| Zaia, AA | 1 |
| Nakanjako, D | 1 |
| Zalwango, F | 1 |
| Wairagala, P | 1 |
| Luboga, F | 1 |
| Andia Biraro, I | 1 |
| Bukirwa, VD | 1 |
| Mboowa, MG | 1 |
| Cose, S | 1 |
| Seeley, J | 1 |
| Elliott, A | 1 |
| Zhao, G | 1 |
| Sun, P | 1 |
| Hao, S | 1 |
| Qu, G | 1 |
| Xing, Y | 1 |
| Xu, X | 1 |
| Maierhofer, M | 1 |
| Rieger, V | 1 |
| Mayr, T | 1 |
| Liu, Y | 3 |
| Zhang, Q | 1 |
| Bigliardi, AP | 1 |
| Fernandes, CLF | 1 |
| Pinto, EA | 1 |
| Dos Santos, M | 1 |
| Garcia, EM | 1 |
| Baisch, PRM | 1 |
| Soares, MCF | 1 |
| Muccillo-Baisch, AL | 1 |
| da Silva Júnior, FMR | 1 |
| Yu, W | 1 |
| Ju, C | 1 |
| Wang, K | 1 |
| Zheng, Z | 1 |
| Martínez-Navarro, EM | 1 |
| Cebrián-Tarancón, C | 1 |
| Moratalla-López, N | 1 |
| Lorenzo, C | 1 |
| Alonso, GL | 1 |
| Salinas, RM | 1 |
| Bermúdez de Castro, JM | 1 |
| Modesto-Mata, M | 1 |
| Martín-Francés, L | 1 |
| García-Campos, C | 1 |
| Martínez de Pinillos, M | 1 |
| Martinón-Torres, M | 1 |
| Hasani, M | 1 |
| Wu, F | 2 |
| Warriner, K | 1 |
| Kurz, M | 1 |
| Gretzke, D | 1 |
| Hörlein, R | 1 |
| Turpault, S | 1 |
| Atzrodt, J | 1 |
| Derdau, V | 1 |
| Yao, Y | 1 |
| Ou, X | 1 |
| Zhao, S | 1 |
| Tian, B | 1 |
| Jin, S | 1 |
| Jiang, Z | 1 |
| Zhou, Z | 1 |
| Liu, M | 2 |
| Jiang, GD | 1 |
| Mou, LH | 1 |
| Chen, JJ | 1 |
| Li, ZY | 1 |
| He, SG | 1 |
| Reale, E | 1 |
| Fustinoni, S | 1 |
| Mercadante, R | 1 |
| Polledri, E | 1 |
| Hopf, NB | 1 |
| Grant, PC | 1 |
| Levy, K | 1 |
| Lattimer, TA | 1 |
| Depner, RM | 1 |
| Kerr, CW | 1 |
| Sato, J | 1 |
| Merenda, MEZ | 1 |
| Uemoto, AT | 1 |
| Dos Santos, MP | 1 |
| Barion, MRL | 1 |
| Carciofi, AC | 1 |
| de Paula Dorigam, JC | 1 |
| Ribeiro, LB | 1 |
| Vasconcellos, RS | 1 |
| Waller, SB | 1 |
| Peter, CM | 1 |
| Hoffmann, JF | 1 |
| Cleff, MB | 1 |
| Faria de, RO | 1 |
| Zani, JL | 1 |
| Martins, BA | 1 |
| Sande, D | 1 |
| Solares, MD | 1 |
| Takahashi, JA | 1 |
| Yang, S | 2 |
| Jia, Y | 1 |
| Yin, C | 1 |
| Zhao, R | 1 |
| Ojha, M | 1 |
| Wu, B | 1 |
| Deepa, M | 1 |
| Mo, J | 1 |
| Au, DW | 1 |
| Wan, MT | 1 |
| Shi, J | 1 |
| Zhang, G | 1 |
| Winkler, C | 1 |
| Kong, RY | 1 |
| Seemann, F | 1 |
| Bianco, M | 1 |
| Calvano, CD | 1 |
| Ventura, G | 1 |
| Bianco, G | 1 |
| Losito, I | 1 |
| Cataldi, TRI | 1 |
| Angiolella, L | 1 |
| Staudt, A | 1 |
| Duarte, PF | 1 |
| Amaral, BPD | 1 |
| Peixoto Andrade, BCO | 1 |
| Simas, NK | 1 |
| Correa Ramos Leal, I | 1 |
| Sangenito, LS | 1 |
| Santos, ALSD | 1 |
| de Oliveira, D | 1 |
| Junges, A | 1 |
| Cansian, RL | 1 |
| Paroul, N | 1 |
| Siu, J | 1 |
| Klingler, L | 1 |
| Hung, CT | 1 |
| Jeong, SH | 1 |
| Smith, S | 1 |
| Tingle, MD | 1 |
| Wagner Mackenzie, B | 1 |
| Biswas, K | 1 |
| Douglas, RG | 1 |
| Oza, AM | 1 |
| Lorusso, D | 1 |
| Aghajanian, C | 1 |
| Oaknin, A | 1 |
| Dean, A | 1 |
| Colombo, N | 1 |
| Weberpals, JI | 1 |
| Clamp, AR | 1 |
| Scambia, G | 1 |
| Leary, A | 1 |
| Holloway, RW | 1 |
| Gancedo, MA | 1 |
| Fong, PC | 1 |
| Goh, JC | 1 |
| O'Malley, DM | 1 |
| Armstrong, DK | 1 |
| Banerjee, S | 1 |
| García-Donas, J | 1 |
| Swisher, EM | 1 |
| Cella, D | 1 |
| Meunier, J | 1 |
| Goble, S | 1 |
| Cameron, T | 1 |
| Maloney, L | 1 |
| Mörk, AC | 1 |
| Bedel, J | 1 |
| Ledermann, JA | 1 |
| Coleman, RL | 1 |
| Vlek, SL | 1 |
| Burm, R | 1 |
| Govers, TM | 1 |
| Vleugels, MPH | 1 |
| Tuynman, JB | 1 |
| Mijatovic, V | 1 |
| Leicht, AS | 1 |
| Connor, J | 1 |
| Conduit, N | 1 |
| Vaquera, A | 1 |
| Gómez, MA | 1 |
| McKay, JA | 1 |
| Church, AL | 1 |
| Rubin, N | 1 |
| Emory, TH | 1 |
| Hoven, NF | 1 |
| Kuehn-Hajder, JE | 1 |
| Nelson, MT | 1 |
| Ramanna, S | 1 |
| Auerbach, EJ | 1 |
| Moeller, S | 1 |
| Bolan, PJ | 1 |
| Fox, NP | 1 |
| Leonard, M | 1 |
| Sjerps, MJ | 1 |
| Chang, EF | 1 |
| Hyun, S | 1 |
| Saejio, A | 1 |
| Shanmugam, S | 1 |
| Liu, X | 1 |
| Sun, M | 1 |
| Bai, Z | 1 |
| Jaque-Fernandez, F | 1 |
| Beaulant, A | 1 |
| Berthier, C | 1 |
| Monteiro, L | 1 |
| Allard, B | 1 |
| Casas, M | 1 |
| Rieusset, J | 1 |
| Jacquemond, V | 1 |
| Góngora-García, OR | 1 |
| Aca-Aca, G | 1 |
| Baz-Rodríguez, SA | 1 |
| Monte, A | 1 |
| Maganaris, C | 1 |
| Baltzopoulos, V | 1 |
| Zamparo, P | 1 |
| Hou, Y | 1 |
| Cai, L | 1 |
| Tu, YJ | 1 |
| Tan, B | 1 |
| Wu, ZH | 1 |
| Yu, HJ | 1 |
| Li, XQ | 1 |
| Yang, AD | 1 |
| Titze, IR | 1 |
| Palaparthi, A | 1 |
| Mau, T | 1 |
| González, MA | 1 |
| Goiri, F | 1 |
| Barandika, JF | 1 |
| García-Pérez, AL | 1 |
| Jatt, LP | 1 |
| Gandhi, MM | 1 |
| Guo, R | 1 |
| Sukhija-Cohen, A | 1 |
| Bhattacharya, D | 1 |
| Tseng, CH | 1 |
| Chew, KW | 1 |
| Onwumere, J | 1 |
| Pia Tek, J | 1 |
| Budnyak, T | 1 |
| Budnyk, S | 1 |
| Karim, Z | 1 |
| Thersleff, T | 1 |
| Kuśtrowski, P | 1 |
| Mathew, AP | 1 |
| Slabon, A | 1 |
| Guo, M | 1 |
| Zhao, T | 1 |
| Xing, Z | 1 |
| Qiu, Y | 1 |
| Pan, K | 1 |
| Zhou, W | 1 |
| Ghassemi Tabrizi, S | 1 |
| Arbuznikov, AV | 1 |
| Jiménez-Hoyos, CA | 1 |
| Kaupp, M | 1 |
| Lin, MH | 2 |
| Bulman, DM | 1 |
| Remucal, CK | 1 |
| Chaplin, BP | 1 |
| Laguerre, A | 1 |
| George, LA | 1 |
| Gall, ET | 1 |
| Emerson, MS | 1 |
| Wang, H | 3 |
| Maginn, EJ | 1 |
| Margulis, CJ | 1 |
| Li, H | 3 |
| Feng, W | 1 |
| Kang, X | 2 |
| Yan, S | 1 |
| Chao, M | 1 |
| Mo, S | 1 |
| Sun, W | 1 |
| Lu, Y | 1 |
| Chen, C | 1 |
| Stevens, DM | 1 |
| Adiseshaiah, P | 1 |
| Dasa, SSK | 1 |
| Potter, TM | 1 |
| Skoczen, SL | 1 |
| Snapp, KS | 1 |
| Cedrone, E | 1 |
| Patel, N | 1 |
| Busman-Sahay, K | 1 |
| Rosen, EP | 1 |
| Sykes, C | 1 |
| Cottrell, M | 1 |
| Dobrovolskaia, MA | 1 |
| Estes, JD | 1 |
| Kashuba, ADM | 1 |
| Stern, ST | 1 |
| Özütemiz, C | 1 |
| Neil, EC | 1 |
| Tanwar, M | 1 |
| Rubin, NT | 1 |
| Ozturk, K | 1 |
| Cayci, Z | 1 |
| Duscha, BD | 1 |
| Kraus, WE | 1 |
| Jones, WS | 1 |
| Robbins, JL | 1 |
| Piner, LW | 1 |
| Huffman, KM | 1 |
| Allen, JD | 1 |
| Annex, BH | 1 |
| Mehmood, T | 1 |
| Ahmad, I | 1 |
| Bibi, S | 1 |
| Mustafa, B | 1 |
| Ali, I | 1 |
| Dahal, RH | 1 |
| Chaudhary, DK | 1 |
| Kim, DU | 1 |
| Kim, J | 1 |
| Yeter, HH | 1 |
| Gonul, I | 1 |
| Guz, G | 1 |
| Helvaci, O | 1 |
| Korucu, B | 1 |
| Akcay, OF | 1 |
| Derici, U | 1 |
| Arinsoy, T | 1 |
| Neffati, R | 1 |
| Judeinstein, P | 1 |
| Rault, J | 1 |
| Xu, Y | 1 |
| Chai, X | 1 |
| Ren, T | 1 |
| Yu, S | 1 |
| Fu, Q | 2 |
| Ye, J | 1 |
| Ge, X | 1 |
| Song, J | 2 |
| Yang, H | 2 |
| El-Baba, TJ | 1 |
| Lutomski, CA | 1 |
| Kantsadi, AL | 1 |
| Malla, TR | 1 |
| John, T | 1 |
| Mikhailov, V | 1 |
| Bolla, JR | 1 |
| Schofield, CJ | 1 |
| Zitzmann, N | 1 |
| Vakonakis, I | 1 |
| Robinson, CV | 1 |
| Langham, MC | 1 |
| Caporale, AS | 1 |
| Wehrli, FW | 1 |
| Parry, S | 1 |
| Schwartz, N | 1 |
| den Boer, RB | 1 |
| Jones, KI | 1 |
| Ash, S | 1 |
| van Boxel, GI | 1 |
| Gillies, RS | 1 |
| O'Donnell, T | 1 |
| Ruurda, JP | 1 |
| Sgromo, B | 1 |
| Silva, MA | 1 |
| Maynard, ND | 1 |
| Sivieri, EM | 1 |
| Eichenwald, EC | 1 |
| Rub, D | 1 |
| Abbasi, S | 1 |
| Krahnert, I | 1 |
| Bolze, A | 1 |
| Gibon, Y | 1 |
| Fernie, AR | 1 |
| Huang, L | 2 |
| Wan, Y | 1 |
| Dang, Z | 1 |
| Yang, P | 1 |
| Yang, Q | 1 |
| Wu, S | 2 |
| Lin, CC | 1 |
| Hsu, CT | 1 |
| Liu, W | 2 |
| Huang, SC | 1 |
| Kortz, U | 1 |
| Mougharbel, AS | 1 |
| Chen, TY | 6 |
| Hu, CW | 1 |
| Lee, JF | 1 |
| Wang, CC | 1 |
| Liao, YF | 1 |
| Li, LJ | 1 |
| Li, L | 2 |
| Peng, S | 1 |
| Stimming, U | 1 |
| Hebbar Kannur, K | 1 |
| Yaqub, TB | 1 |
| Pupier, C | 1 |
| Héau, C | 1 |
| Cavaleiro, A | 1 |
| Yamamoto, S | 1 |
| Ono, A | 1 |
| Matsui, J | 1 |
| Hoshino, N | 1 |
| Akutagawa, T | 1 |
| Miyashita, T | 1 |
| Mitsuishi, M | 1 |
| Patel, SM | 1 |
| Smith, TG | 1 |
| Morton, M | 1 |
| Stiers, KM | 1 |
| Seravalli, J | 1 |
| Mayclin, SJ | 1 |
| Edwards, TE | 1 |
| Tanner, JJ | 1 |
| Becker, DF | 1 |
| Butcher, TW | 1 |
| Yang, JL | 1 |
| Hartwig, JF | 1 |
| Yu, MF | 1 |
| Xia, ZZ | 1 |
| Yao, JC | 1 |
| Feng, Z | 1 |
| Li, DH | 1 |
| Liu, T | 1 |
| Cheng, GJ | 1 |
| He, DL | 1 |
| Li, XH | 1 |
| Huurman, R | 1 |
| Schinkel, AFL | 1 |
| de Jong, PL | 1 |
| van Slegtenhorst, MA | 1 |
| Hirsch, A | 1 |
| Michels, M | 1 |
| Kataja, A | 1 |
| Tarvasmäki, T | 1 |
| Lassus, J | 1 |
| Sionis, A | 1 |
| Mebazaa, A | 1 |
| Pulkki, K | 1 |
| Banaszewski, M | 1 |
| Carubelli, V | 1 |
| Hongisto, M | 1 |
| Jankowska, E | 1 |
| Jurkko, R | 1 |
| Jäntti, T | 1 |
| Kasztura, M | 1 |
| Parissis, J | 1 |
| Sabell, T | 1 |
| Silva-Cardoso, J | 1 |
| Spinar, J | 1 |
| Tolppanen, H | 1 |
| Harjola, VP | 1 |
| Carsetti, A | 1 |
| Damiani, E | 1 |
| Casarotta, E | 1 |
| Scorcella, C | 1 |
| Domizi, R | 1 |
| Gasparri, F | 1 |
| Gabbanelli, V | 1 |
| Pantanetti, S | 1 |
| Carozza, R | 1 |
| Adrario, E | 1 |
| Donati, A | 1 |
| Almada, E | 1 |
| Pariani, A | 1 |
| Rivabella Maknis, T | 1 |
| Hidalgo, F | 1 |
| Vena, R | 1 |
| Favre, C | 1 |
| Larocca, MC | 1 |
| Lu, ZY | 1 |
| Jiang, WD | 1 |
| Wu, P | 1 |
| Kuang, SY | 1 |
| Tang, L | 1 |
| Zhou, XQ | 1 |
| Feng, L | 1 |
| Leal, M | 1 |
| Zampini, IC | 1 |
| Mercado, MI | 1 |
| Moreno, MA | 1 |
| Simirgiotis, MJ | 1 |
| Bórquez, J | 1 |
| Ponessa, G | 1 |
| Isla, MI | 1 |
| Saliu, IO | 1 |
| Amoo, ZA | 1 |
| Khan, MF | 1 |
| Olaleye, MT | 1 |
| Rema, V | 1 |
| Akinmoladun, AC | 1 |
| Khan, AU | 1 |
| Rahman, AU | 1 |
| Yuan, Q | 1 |
| Ahmad, A | 1 |
| Khan, ZUH | 1 |
| Mahnashi, MH | 1 |
| Alyami, BA | 1 |
| Alqahtani, YS | 1 |
| Ullah, S | 1 |
| Wirman, AP | 1 |
| Gao, M | 1 |
| Deng, L | 1 |
| Zhang, K | 1 |
| Gao, D | 1 |
| Balkissou, AD | 1 |
| Poka-Mayap, V | 1 |
| Massongo, M | 1 |
| Djenabou, A | 1 |
| Endale-Mangamba, LM | 1 |
| Olomo, EJ | 1 |
| Boulleys-Nana, JR | 1 |
| Diffo-Sonkoue, L | 1 |
| Adidigue-Ndiome, R | 1 |
| Alexandra, AJE | 1 |
| Haman-Wabi, AB | 1 |
| Adama, S | 1 |
| Iddi-Faical, A | 1 |
| Pefura-Yone, EW | 1 |
| Zhao, Q | 1 |
| Tong, W | 1 |
| Ge, C | 1 |
| Zhao, D | 3 |
| Norbäck, D | 1 |
| Li, B | 2 |
| Zhao, Z | 2 |
| Huang, C | 1 |
| Qian, H | 1 |
| Yang, X | 1 |
| Sun, Y | 1 |
| Sundell, J | 1 |
| Deng, Q | 1 |
| Kim, HJ | 1 |
| Jeon, JW | 1 |
| Hwang, SM | 1 |
| Chu, KI | 1 |
| Cha, YH | 1 |
| Kwak, YD | 1 |
| Choi, SD | 1 |
| Aslam, M | 1 |
| Kim, CG | 1 |
| Yang, E | 1 |
| Yang, W | 1 |
| Kalyoncu, Ş | 1 |
| Yilmaz, B | 1 |
| Demir, M | 1 |
| Tuncer, M | 2 |
| Bozdağ, Z | 1 |
| Ince, O | 1 |
| Bozdayi, MA | 1 |
| Ulusal, H | 1 |
| Taysi, S | 1 |
| Wu, J | 1 |
| Bai, Y | 2 |
| El-Sisi, AEE | 2 |
| Sokar, SS | 2 |
| Shebl, AM | 2 |
| Mohamed, DZ | 2 |
| Abu-Risha, SE | 2 |
| Chen, KH | 6 |
| Chai, HT | 3 |
| Chen, CH | 5 |
| Huang, CR | 2 |
| Chiang, JY | 3 |
| Sung, PH | 7 |
| Chu, YC | 3 |
| Yip, HK | 8 |
| Fenton-Navarro, B | 1 |
| Garduño Ríos, D | 1 |
| Torner, L | 1 |
| Letechipía-Vallejo, G | 2 |
| Cervantes, M | 2 |
| Hu, C | 1 |
| Zhao, L | 1 |
| Zhang, F | 1 |
| Li, HW | 1 |
| Ying, P | 1 |
| Cai, QQ | 1 |
| Yang, ZH | 1 |
| Wu, XL | 1 |
| Li, ZT | 1 |
| Jin, L | 1 |
| Lin, J | 1 |
| Fan, ZL | 1 |
| Zeng, Z | 1 |
| Huang, HF | 1 |
| Lin, D | 1 |
| Leite, AA | 1 |
| Brandão, JCM | 1 |
| Sakae, TM | 1 |
| Marinho, M | 1 |
| Camargo, CR | 1 |
| Oliveira-Junior, IS | 1 |
| Pehlivanoglu, B | 1 |
| Sürücü, SH | 1 |
| Isbir, T | 1 |
| Yang, CC | 5 |
| Li, YC | 1 |
| Nasoni, MG | 1 |
| Carloni, S | 1 |
| Canonico, B | 1 |
| Burattini, S | 1 |
| Cesarini, E | 1 |
| Papa, S | 1 |
| Pagliarini, M | 1 |
| Ambrogini, P | 1 |
| Balduini, W | 1 |
| Luchetti, F | 1 |
| Novais, AA | 1 |
| Chuffa, LGA | 1 |
| Zuccari, DAPC | 1 |
| Chen, YT | 3 |
| Chuang, FC | 1 |
| Huang, KH | 1 |
| Ma, Z | 1 |
| Xin, Z | 1 |
| Di, W | 1 |
| Mortezaee, K | 1 |
| Khanlarkhani, N | 1 |
| Wolf, A | 1 |
| Lusczek, ER | 1 |
| Beilman, GJ | 1 |
| Wang, ML | 1 |
| Wei, CH | 1 |
| Wang, WD | 1 |
| Wang, JS | 1 |
| Wang, JJ | 4 |
| Özkan, N | 1 |
| Ersoy, ÖF | 1 |
| Özsoy, Z | 1 |
| Çakır, E | 1 |
| Humar, B | 1 |
| Gupta, A | 1 |
| Maurizio, E | 1 |
| Borgeaud, N | 1 |
| Graf, R | 1 |
| Clavien, PA | 1 |
| Tian, Y | 1 |
| Celer, M | 1 |
| Mogulkoc, R | 2 |
| Baltaci, AK | 2 |
| Dasdelen, D | 1 |
| Laurindo, FRM | 1 |
| Lin, YW | 1 |
| Hung, CY | 1 |
| Tai, SH | 2 |
| Huang, SY | 3 |
| Chang, CC | 1 |
| Hung, HY | 1 |
| Lee, EJ | 5 |
| Souza, PC | 1 |
| Santos, EBD | 1 |
| Motta, GL | 1 |
| Bona, SR | 1 |
| Schaefer, PG | 1 |
| Campagnol, D | 1 |
| Bortolini, T | 1 |
| Corso, CO | 1 |
| Wang, W | 1 |
| Zeng, R | 1 |
| Ni, L | 1 |
| Lai, Z | 1 |
| Wei, N | 1 |
| Pu, Y | 1 |
| Yang, Z | 1 |
| Pan, Y | 1 |
| Lan, S | 1 |
| Luo, X | 1 |
| Bi, C | 1 |
| Kryl'skii, ED | 1 |
| Popova, TN | 1 |
| Safonova, OA | 1 |
| Stolyarova, AO | 1 |
| Razuvaev, GA | 1 |
| de Carvalho, MAP | 1 |
| Chen, DQ | 1 |
| Feng, YL | 1 |
| Liu, JR | 1 |
| Vaziri, ND | 1 |
| Zhao, YY | 1 |
| Saat, N | 1 |
| Risvanli, A | 1 |
| Dogan, H | 1 |
| Onalan, E | 1 |
| Akpolat, N | 1 |
| Seker, I | 1 |
| Sahna, E | 6 |
| Boncompagni, E | 2 |
| Bejaoui, M | 2 |
| Freitas, I | 2 |
| Pantazi, E | 1 |
| Folch-Puy, E | 1 |
| Garcia-Gil, FA | 4 |
| Roselló-Catafau, J | 3 |
| Yapca, OE | 1 |
| Turan, MI | 1 |
| Cetin, N | 1 |
| Borekci, B | 1 |
| Gul, MA | 1 |
| Kang, JW | 3 |
| Cho, HI | 1 |
| Lee, SM | 4 |
| Ahmadiasl, N | 2 |
| Banaei, S | 3 |
| Alihemati, A | 1 |
| Baradaran, B | 1 |
| Azimian, E | 1 |
| Halladin, NL | 2 |
| Busch, SE | 1 |
| Jensen, SE | 1 |
| Hansen, HS | 1 |
| Zaremba, T | 1 |
| Aarøe, J | 1 |
| Rosenberg, J | 1 |
| Gögenur, I | 1 |
| Bhattacharya, P | 1 |
| Pandey, AK | 1 |
| Paul, S | 1 |
| Patnaik, R | 1 |
| Ahsen, A | 1 |
| Gonul, Y | 2 |
| Genc, A | 1 |
| Ulu, MS | 1 |
| Yagmurca, M | 1 |
| Kocogullari, CU | 1 |
| Celik, S | 2 |
| Yuksel, S | 1 |
| de Souza, AV | 1 |
| Golim, MA | 1 |
| Deffune, E | 1 |
| Domingues, MA | 1 |
| de Carvalho, LR | 1 |
| Vianna, IG | 1 |
| Castiglia, YM | 1 |
| Vianna, PT | 1 |
| Feng, D | 1 |
| Xu, M | 1 |
| Gao, A | 1 |
| Zhang, L | 2 |
| Cui, Y | 1 |
| Chen, G | 1 |
| Feng, Y | 1 |
| Yan, J | 1 |
| Fan, C | 1 |
| Jiang, S | 1 |
| Qu, Y | 1 |
| Khodosovskiĭ, MN | 1 |
| Zinchuk, VV | 1 |
| Kang, SM | 1 |
| Lee, WT | 3 |
| Park, KA | 1 |
| Lee, KM | 1 |
| Lee, JE | 1 |
| Ni, YF | 1 |
| Wang, WC | 1 |
| Du, HY | 1 |
| Zhang, H | 2 |
| Zhang, WD | 1 |
| Oguz, E | 4 |
| Yilmaz, Z | 1 |
| Ozbilge, H | 3 |
| Baba, F | 6 |
| Tabur, S | 1 |
| Yerer, MB | 1 |
| Hekimoglu, A | 2 |
| Ozban, M | 1 |
| Aydin, C | 1 |
| Cevahir, N | 1 |
| Yenisey, C | 1 |
| Birsen, O | 1 |
| Gumrukcu, G | 1 |
| Aydin, B | 1 |
| Berber, I | 1 |
| Geyik, S | 1 |
| Yiğiter, R | 1 |
| Akçalı, A | 1 |
| Deniz, H | 1 |
| Murat Geyik, A | 1 |
| Ali Elçi, M | 1 |
| Hafız, E | 1 |
| Chang, CL | 2 |
| Sun, CK | 2 |
| Chiang, HJ | 4 |
| Huang, TH | 4 |
| Chen, YL | 5 |
| Zhen, YY | 3 |
| Chung, SY | 2 |
| Tong, MS | 1 |
| Chang, HW | 3 |
| Chen, HH | 2 |
| Hadj Ayed Tka, K | 1 |
| Mahfoudh Boussaid, A | 1 |
| Kammoun, R | 1 |
| Ghoul Mazgar, S | 1 |
| Rosello Catafau, J | 1 |
| Ben Abdennebi, H | 2 |
| Sheu, JJ | 1 |
| Zhou, L | 1 |
| An, H | 1 |
| Jiang, C | 1 |
| Taghizadieh, M | 1 |
| Hajipour, B | 1 |
| Asl N, A | 1 |
| Khodadadi, A | 1 |
| Somi, MH | 1 |
| Banei, M | 1 |
| Chua, S | 1 |
| Kao, GS | 2 |
| Lee, MS | 1 |
| Yilmaz, M | 2 |
| Esteban-Zubero, E | 2 |
| López-Pingarrón, L | 2 |
| Alatorre-Jiménez, MA | 2 |
| Ramírez, JM | 1 |
| Tan, DX | 8 |
| García, JJ | 3 |
| Chang, YC | 2 |
| Hsu, SY | 1 |
| Lee, FY | 1 |
| Iñigo-Gil, P | 1 |
| Yuan, D | 1 |
| Collage, RD | 1 |
| Huang, H | 2 |
| Kautza, BC | 1 |
| Lewis, AJ | 1 |
| Zuckerbraun, BS | 1 |
| Tsung, A | 1 |
| Angus, DC | 1 |
| Rosengart, MR | 1 |
| Ozsoy, M | 1 |
| Ozkececi, ZT | 1 |
| Bali, A | 1 |
| Celep, RB | 1 |
| Koçak, A | 2 |
| Adali, F | 1 |
| Tosun, M | 1 |
| Asghari, A | 1 |
| Akbari, G | 1 |
| Meghdadi, A | 1 |
| Mortazavi, P | 1 |
| Alihemmati, A | 1 |
| Sekmenli, T | 1 |
| Gunduz, M | 1 |
| Öztürk, B | 1 |
| Karabağlı, P | 1 |
| Ciftci, I | 1 |
| Tekin, G | 1 |
| Sarkar, S | 1 |
| Mukherjee, A | 1 |
| Das, N | 1 |
| Swarnakar, S | 1 |
| Baykara, B | 1 |
| Tekmen, I | 1 |
| Pekcetin, C | 1 |
| Ulukus, C | 1 |
| Tuncel, P | 1 |
| Sagol, O | 1 |
| Ormen, M | 1 |
| Ozogul, C | 1 |
| Jiang, CL | 1 |
| Yang, BX | 1 |
| Jia, R | 1 |
| Fadillioglu, E | 2 |
| Kurcer, Z | 6 |
| Parlakpinar, H | 6 |
| Iraz, M | 3 |
| Gursul, C | 1 |
| Hung, YC | 2 |
| Chen, WL | 1 |
| Lee, MY | 3 |
| Wu, TS | 4 |
| Koh, PO | 3 |
| Li, ZR | 1 |
| Shen, MH | 1 |
| Niu, WM | 1 |
| Yurtçu, M | 1 |
| Abasiyanik, A | 1 |
| Avunduk, MC | 2 |
| Muhtaroğlu, S | 1 |
| Li, JY | 2 |
| Yin, HZ | 1 |
| Gu, X | 1 |
| Zhou, Y | 2 |
| Zhang, WH | 2 |
| Qin, YM | 1 |
| Aral, F | 2 |
| Zhai, W | 1 |
| Jungraithmayr, W | 1 |
| De Meester, I | 1 |
| Inci, I | 3 |
| Augustyns, K | 1 |
| Arni, S | 1 |
| Hillinger, S | 1 |
| Scharpé, S | 1 |
| Weder, W | 3 |
| Korom, S | 2 |
| Kesik, V | 2 |
| Guven, A | 2 |
| Vurucu, S | 1 |
| Tunc, T | 2 |
| Uysal, B | 2 |
| Gundogdu, G | 1 |
| Oztas, E | 3 |
| Korkmaz, A | 3 |
| Kaur, C | 1 |
| Sivakumar, V | 1 |
| Foulds, WS | 1 |
| Luu, CD | 1 |
| Ling, EA | 1 |
| Nickkholgh, A | 2 |
| Yi, X | 1 |
| Bruns, H | 1 |
| Gross, ML | 1 |
| Hoffmann, K | 2 |
| Mohr, E | 1 |
| Zorn, M | 2 |
| Büchler, MW | 2 |
| Schemmer, P | 2 |
| Odaci, E | 1 |
| Kaplan, S | 1 |
| Domínguez Rodríguez, A | 1 |
| Abreu González, P | 1 |
| Ersoz, N | 1 |
| Cayci, T | 1 |
| Turk, E | 1 |
| Akgul, EO | 1 |
| Cetiner, S | 1 |
| Hamada, F | 2 |
| Watanabe, K | 3 |
| Wakatsuki, A | 7 |
| Nagai, R | 2 |
| Shinohara, K | 5 |
| Hayashi, Y | 2 |
| Imamura, R | 2 |
| Fukaya, T | 5 |
| Guo, Y | 1 |
| Duan, Q | 2 |
| Padrissa-Altés, S | 2 |
| Mahfoudh-Boussaid, A | 1 |
| Wang, WZ | 3 |
| Fang, XH | 3 |
| Stephenson, LL | 3 |
| Khiabani, KT | 3 |
| Zamboni, WA | 3 |
| Park, OK | 1 |
| Yoo, KY | 1 |
| Lee, CH | 1 |
| Choi, JH | 1 |
| Hwang, IK | 1 |
| Park, JH | 1 |
| Kwon, YG | 1 |
| Kim, YM | 1 |
| Won, MH | 1 |
| Demirin, H | 1 |
| Karaoglu, A | 1 |
| Temiz, A | 1 |
| Ozler, M | 1 |
| Sadir, S | 1 |
| Atabek, C | 1 |
| Kul, M | 1 |
| Lin, HW | 1 |
| Chen, YH | 1 |
| Cho, EH | 1 |
| Kanter, M | 1 |
| Villapol, S | 1 |
| Fau, S | 1 |
| Renolleau, S | 1 |
| Biran, V | 1 |
| Charriaut-Marlangue, C | 1 |
| Baud, O | 1 |
| Erdem, M | 1 |
| Bostan, B | 1 |
| Güneş, T | 1 |
| Özkan, F | 1 |
| Sen, C | 1 |
| Özyurt, H | 1 |
| Köseoğlu, RD | 1 |
| Erdoğan, H | 1 |
| Kondoh, T | 1 |
| Ueta, Y | 1 |
| Torii, K | 1 |
| Ben Abnennebi, H | 1 |
| Koh, EJ | 1 |
| Santana-Rodríguez, N | 1 |
| Clavo, B | 1 |
| Llontop, P | 1 |
| López, A | 1 |
| García-Castellano, JM | 1 |
| Machín, RP | 1 |
| Ponce, MA | 1 |
| Fiuza, MD | 1 |
| García-Herrera, R | 1 |
| Brito, Y | 1 |
| Yordi, NA | 1 |
| Chirino, R | 1 |
| Baksheev, VI | 1 |
| Kolomoets, NM | 1 |
| Patschan, D | 1 |
| Hildebrandt, A | 1 |
| Rinneburger, J | 1 |
| Wessels, JT | 1 |
| Patschan, S | 1 |
| Becker, JU | 1 |
| Henze, E | 1 |
| Krüger, A | 1 |
| Müller, GA | 1 |
| Chiu, MH | 1 |
| Su, CL | 2 |
| Chen, CF | 2 |
| Wang, D | 2 |
| Yeh, JH | 1 |
| Chen, TH | 1 |
| Kireev, RA | 1 |
| Cuesta, S | 2 |
| Ibarrola, C | 2 |
| Bela, T | 1 |
| Moreno Gonzalez, E | 1 |
| Vara, E | 2 |
| Tresguerres, JA | 2 |
| Koksal, M | 1 |
| Eren, MA | 1 |
| Ciftci, H | 1 |
| Demir, ME | 1 |
| Take, G | 1 |
| Ocak, AR | 1 |
| Aksoy, N | 3 |
| Ulas, T | 1 |
| Sinanoglu, O | 3 |
| Sezgin, G | 2 |
| Ozturk, G | 3 |
| Tuncdemir, M | 2 |
| Guney, S | 2 |
| Aksungar, FB | 1 |
| Yener, N | 1 |
| Tsoulfas, G | 1 |
| Ekici, S | 1 |
| Doğan Ekici, AI | 1 |
| Benli Aksungar, F | 1 |
| Turan, G | 1 |
| Lüleci, N | 1 |
| Martins, PN | 1 |
| Markmann, JF | 1 |
| Wallace, CG | 1 |
| Chang, LT | 1 |
| Tsai, TH | 1 |
| Leu, S | 1 |
| Tsai, CY | 1 |
| Yeh, KH | 1 |
| Yen, CH | 1 |
| Kireev, R | 1 |
| Bitoun, S | 1 |
| Tejerina, A | 1 |
| Moreno, E | 1 |
| Rodella, LF | 1 |
| Favero, G | 1 |
| Foglio, E | 1 |
| Rossini, C | 1 |
| Castrezzati, S | 1 |
| Lonati, C | 1 |
| Rezzani, R | 1 |
| Lochner, A | 2 |
| Huisamen, B | 2 |
| Nduhirabandi, F | 1 |
| Hernández, JA | 1 |
| El-Abhar, HS | 1 |
| Shaalan, M | 1 |
| Barakat, M | 1 |
| El-Denshary, ES | 1 |
| Jaworek, J | 2 |
| Leja-Szpak, A | 2 |
| Bonior, J | 2 |
| Nawrot, K | 1 |
| Tomaszewska, R | 1 |
| Stachura, J | 2 |
| Sendur, R | 1 |
| Pawlik, W | 1 |
| Brzozowski, T | 3 |
| Konturek, SJ | 5 |
| Guo, JD | 1 |
| Xing, SH | 1 |
| Gu, SL | 1 |
| Dai, TJ | 1 |
| Cheung, RT | 3 |
| Sener, G | 8 |
| Sehirli, AO | 5 |
| Paskaloğlu, K | 2 |
| Dülger, GA | 2 |
| Alican, I | 2 |
| Chen, JC | 1 |
| Ng, CJ | 1 |
| Chiu, TF | 1 |
| Chen, HM | 1 |
| Kunduzova, OR | 1 |
| Escourrou, G | 1 |
| Seguelas, MH | 2 |
| Delagrange, P | 1 |
| De La Farge, F | 1 |
| Cambon, C | 1 |
| Parini, A | 2 |
| Tosun, O | 1 |
| Kaçmaz, A | 3 |
| Arbak, S | 3 |
| Ersoy, Y | 2 |
| Ayanoğlu-Dülger, G | 2 |
| Ozturk, F | 1 |
| Cigremis, Y | 2 |
| Acet, A | 3 |
| Okatani, Y | 4 |
| Enzan, H | 1 |
| Miyahara, Y | 1 |
| User, Y | 1 |
| Ozkan, S | 2 |
| Tilki, M | 2 |
| Yeğen, BC | 2 |
| Erten, SF | 1 |
| Ozdemir, I | 1 |
| Aydemir, S | 1 |
| Colak, A | 1 |
| Reeder, BS | 1 |
| Bülbüller, N | 1 |
| Cetinkaya, Z | 1 |
| Akkus, MA | 1 |
| Cifter, C | 1 |
| Ilhan, YS | 1 |
| Dogru, O | 1 |
| Aygen, E | 1 |
| Gupta, S | 1 |
| Kaul, CL | 1 |
| Sharma, SS | 1 |
| Kilic, E | 2 |
| Kilic, U | 2 |
| Yulug, B | 1 |
| Hermann, DM | 1 |
| Rodríguez-Reynoso, S | 2 |
| Leal, C | 2 |
| Portilla-de Buen, E | 1 |
| Castillo, JC | 1 |
| Ramos-Solano, F | 1 |
| Andrabi, SA | 1 |
| Sayeed, I | 1 |
| Siemen, D | 1 |
| Wolf, G | 1 |
| Horn, TF | 1 |
| Jung, FJ | 1 |
| Yang, L | 1 |
| Härter, L | 1 |
| Schneiter, D | 1 |
| Lardinois, D | 1 |
| Keel, M | 1 |
| Andreadou, I | 1 |
| Iliodromitis, EK | 1 |
| Mikros, E | 1 |
| Bofilis, E | 1 |
| Zoga, A | 1 |
| Constantinou, M | 1 |
| Tsantili-Kakoulidou, A | 1 |
| Kremastinos, DT | 1 |
| Pei, Z | 1 |
| Turkoz, Y | 2 |
| Celik, O | 1 |
| Hascalik, S | 1 |
| Hascalik, M | 1 |
| Mizrak, B | 1 |
| Yologlu, S | 1 |
| Sayan, H | 3 |
| Ozacmak, VH | 3 |
| Ozen, OA | 1 |
| Coskun, O | 1 |
| Arslan, SO | 3 |
| Sezen, SC | 1 |
| Aktas, RG | 2 |
| Ates, B | 1 |
| Yilmaz, I | 1 |
| Geckil, H | 1 |
| Birincioglu, M | 1 |
| Fiskin, K | 1 |
| Ikenoue, N | 3 |
| Yokota, K | 1 |
| Kavakli, A | 1 |
| Yahsi, S | 1 |
| Ogeturk, M | 1 |
| Leon, J | 2 |
| Altaner, S | 1 |
| Sileri, P | 1 |
| Sica, GS | 1 |
| Gentileschi, P | 1 |
| Venza, M | 1 |
| Benavoli, D | 1 |
| Jarzembowski, T | 1 |
| Manzelli, A | 1 |
| Gaspari, AL | 1 |
| Baynosa, RC | 1 |
| User, EY | 1 |
| Erkanli, K | 1 |
| Kayalar, N | 1 |
| Erkanli, G | 1 |
| Ercan, F | 1 |
| Kirali, K | 1 |
| Gelir, E | 1 |
| Srinivasan, V | 1 |
| Pandi-Perumal, SR | 1 |
| Maestroni, GJ | 1 |
| Esquifino, AI | 1 |
| Hardeland, R | 1 |
| Cardinali, DP | 1 |
| Manchester, LC | 3 |
| Sainz, RM | 2 |
| Mayo, JC | 2 |
| Vazan, R | 1 |
| Pancza, D | 1 |
| Béder, I | 1 |
| Styk, J | 1 |
| Han, YX | 1 |
| Zhang, SH | 1 |
| Wang, XM | 1 |
| Wu, JB | 1 |
| Siu, AW | 1 |
| Maldonado, M | 1 |
| Sanchez-Hidalgo, M | 1 |
| Muñoz-Casares, FC | 1 |
| Padillo, FJ | 1 |
| Briceño, J | 1 |
| Collado, JA | 1 |
| Muñoz-Castañeda, JR | 1 |
| Ortega, R | 1 |
| Cruz, A | 1 |
| Túnez, I | 1 |
| Montilla, P | 1 |
| Pera, C | 1 |
| Muntané, J | 1 |
| Kuo, YL | 2 |
| Lin, SC | 1 |
| Sert, G | 1 |
| Ozer Sehirli, A | 1 |
| Gedik, N | 1 |
| Cay, A | 1 |
| Imamoğlu, M | 1 |
| Unsal, MA | 1 |
| Aydin, S | 1 |
| Alver, A | 1 |
| Akyol, A | 1 |
| Sarihan, H | 1 |
| Gurlek, A | 1 |
| Celik, M | 1 |
| Aydogan, H | 1 |
| Bay-Karabulut, A | 1 |
| Deniz, E | 1 |
| Colakoglu, N | 1 |
| Sari, A | 1 |
| Sonmez, MF | 1 |
| Tugrul, I | 1 |
| Oktar, S | 1 |
| Ilhan, S | 1 |
| Tang, Q | 1 |
| Zou, LY | 1 |
| Liu, S | 1 |
| Chen, ST | 1 |
| Hsu, YS | 1 |
| Chang, GL | 1 |
| Lu, T | 1 |
| Bertuglia, S | 2 |
| Kalkan, E | 1 |
| Ciçek, O | 1 |
| Unlü, A | 1 |
| Abuşoglu, S | 1 |
| Kalkan, SS | 1 |
| Baysefer, A | 1 |
| Yin, R | 1 |
| Zhu, J | 1 |
| Wang, C | 1 |
| Sheng, Y | 1 |
| Dong, G | 1 |
| Li, D | 1 |
| Jing, H | 1 |
| Celik, H | 2 |
| Cakir, H | 1 |
| Gezen, MR | 1 |
| Aktoz, T | 1 |
| Aydogdu, N | 1 |
| Alagol, B | 1 |
| Yalcin, O | 1 |
| Huseyinova, G | 1 |
| Atakan, IH | 1 |
| Celik, N | 1 |
| Vardi, N | 1 |
| Tasdemir, S | 1 |
| Moralí, G | 1 |
| Tamura, H | 1 |
| Nawrot-Porabka, K | 1 |
| Szklarczyk, J | 1 |
| Kot, M | 1 |
| Pawlik, WW | 1 |
| Kim, SH | 1 |
| Liang, R | 1 |
| Kern, M | 1 |
| Schneider, H | 1 |
| Sobirey, M | 1 |
| Mias, C | 1 |
| Trouche, E | 1 |
| Calcagno, F | 1 |
| Dignat-George, F | 1 |
| Sabatier, F | 1 |
| Piercecchi-Marti, MD | 1 |
| Daniel, L | 1 |
| Bianchi, P | 1 |
| Calise, D | 1 |
| Bourin, P | 1 |
| Cussac, D | 1 |
| Marchiafava, PL | 1 |
| Colantuoni, A | 1 |
| Konturek, PC | 3 |
| Majka, J | 1 |
| Zembala, M | 2 |
| Hahn, EG | 3 |
| Dembinski, A | 1 |
| Mytar, B | 1 |
| Cho, S | 1 |
| Joh, TH | 1 |
| Baik, HH | 1 |
| Dibinis, C | 1 |
| Volpe, BT | 1 |
| De La Lastra, CA | 2 |
| Cabeza, J | 2 |
| Motilva, V | 2 |
| Martin, MJ | 2 |
| Pajdo, R | 1 |
| Bielanski, W | 1 |
| Brzozowska, I | 1 |
| Qi, W | 1 |
| Kim, SJ | 1 |
| El-Sokkary, GH | 1 |
| Izumiya, C | 1 |
| Li, XJ | 2 |
| Zhang, LM | 2 |
| Gu, J | 1 |
| Zhang, AZ | 1 |
| Sun, FY | 2 |
| Cuzzocrea, S | 3 |
| Costantino, G | 2 |
| Mazzon, E | 2 |
| Micali, A | 1 |
| De Sarro, A | 2 |
| Caputi, AP | 2 |
| Ling, X | 1 |
| Lu, SD | 1 |
| Borlongan, CV | 1 |
| Yamamoto, M | 1 |
| Takei, N | 1 |
| Kumazaki, M | 1 |
| Ungsuparkorn, C | 1 |
| Hida, H | 1 |
| Sanberg, PR | 1 |
| Nishino, H | 1 |
| Kazez, A | 2 |
| Demirbağ, M | 2 |
| Ustündağ, B | 2 |
| Ozercan, IH | 2 |
| Sağlam, M | 1 |
| Gitto, E | 1 |
| Fulia, F | 1 |
| Serraino, I | 1 |
| Cordaro, S | 1 |
| Barberi, I | 1 |
| Canatan, H | 1 |
| Halifeoglu, I | 1 |
| Simonini, G | 1 |
| Pignone, A | 1 |
| Generini, S | 1 |
| Falcini, F | 1 |
| Cerinic, MM | 1 |
| Gabriele, S | 1 |
| Alberto, P | 1 |
| Sergio, G | 1 |
| Fernanda, F | 1 |
| Marco, MC | 1 |
| Salie, R | 1 |
| Harper, I | 1 |
| Cillie, C | 1 |
| Genade, S | 1 |
| Moolman, J | 1 |
| Taniguchi, K | 1 |
| Portilla, E | 1 |
| Olivares, N | 1 |
| Muñiz, J | 1 |
| Sinha, K | 1 |
| Degaonkar, MN | 1 |
| Jagannathan, NR | 1 |
| Gupta, YK | 1 |
| Inci, D | 1 |
| Dutly, A | 1 |
| Boehler, A | 1 |
| Ayar, A | 1 |
| Tug, N | 1 |
| Simsek, M | 1 |
| Ozercan, I | 1 |
| Cikim, G | 1 |
| Bildirici, I | 1 |
| Keyer-Uysal, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intracoronary Injection of Melatonin for Patients With ST-elevation Myocardial Infarction: a Placebo Controlled Randomized Study[NCT01172171] | Phase 2 | 41 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| The Effect of Remote Ischemic Preconditioning on the Postoperative Liver Function in Living Donor Hepatectomy: a Randomized Clinical Trial[NCT03386435] | 160 participants (Actual) | Interventional | 2016-08-22 | Completed | |||
| Light Therapy in Cardiopulmonary Bypass Surgery[NCT02928887] | 0 participants (Actual) | Interventional | 2020-09-01 | Withdrawn (stopped due to Cardiac surgeon collaborator has left the institution) | |||
| Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies - A Randomised, Controlled Clinical Trial[NCT02889432] | Phase 2 | 40 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting | ||
| Dead Mesenchymal Stem Cells for the Treatment of Radiation Lung Injury[NCT06021067] | Phase 1/Phase 2 | 15 participants (Anticipated) | Interventional | 2023-09-10 | Recruiting | ||
| The Protective Effect of Melatonin in Patients Under Carotid Endarterectomy[NCT03115034] | Phase 4 | 60 participants (Actual) | Interventional | 2016-06-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The incidence of delayed recovery of hepatic function (DRHF) were used as surrogate parameters indicating the possible benefits of RIPC. DRHF was defined based on a proposal by the International Study Group of Liver Surgery, as follows: an impaired ability of the liver to maintain its synthetic, excretory, and detoxifying functions, which are characterized by an increased PT INR and concomitant hyperbilirubinemia (considering the normal limits of the local laboratory) on or after postoperative day 5. The normal upper limits of PT and bilirubin in our institutional laboratory were 1.30 INR and 1.2 mg/dL, respectively. If either the PT INR or serum bilirubin concentration was preoperatively elevated, DRHF was defined by an increasing PT INR and increasing serum bilirubin concentration on or after postoperative day 5 (compared with the values of the previous day). (NCT03386435)
Timeframe: postoperative 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| RIPC | 5 |
| Control | 0 |
The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal aspartate aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy. (NCT03386435)
Timeframe: within 7 days after operation
| Intervention | IU/L (Mean) |
|---|---|
| RIPC | 145 |
| Control | 152 |
The postoperative liver regeneration index (LRI) at postoperative 1 month ) was used as surrogate parameters indicating the possible benefits of RIPC. The LRI was defined as [(VLR - VFLR)/VFLR)] × 100, where VLR is the volume of the liver remnant and VFLR is the volume of the future liver remnant. Liver volume was calculated by CT volumetry using 3-mm-thick dynamic CT images. The graft weight was subtracted from the total liver volume to define the future liver remnant. (NCT03386435)
Timeframe: 1 month
| Intervention | percentage of liver volume (Mean) |
|---|---|
| RIPC | 83.3 |
| Control | 94.9 |
The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal alanine aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy (NCT03386435)
Timeframe: within 7 days after operation
| Intervention | IU/L (Mean) |
|---|---|
| RIPC | 148 |
| Control | 152 |
29 reviews available for melatonin and Reperfusion Injury
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Pharmacological Benefits and Risk of Using Hormones in Organ Perfusion and Preservation Solutions in the Aspect of Minimizing Hepatic Ischemia-Reperfusion Injury during Storage.
Topics: Animals; Dopamine; Glucagon; Hormones; Humans; Liver; Liver Transplantation; Melatonin; Organ Preser | 2019 |
The Role of Hormones and Trophic Factors as Components of Preservation Solutions in Protection of Renal Function before Transplantation: A Review of the Literature.
Topics: Adrenocorticotropic Hormone; Alprostadil; Animals; Hormones; Humans; Intercellular Signaling Peptide | 2020 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Melatonin and regulation of autophagy: Mechanisms and therapeutic implications.
Topics: Animals; Autophagy; Cell Death; Humans; Melatonin; Neoplasms; Neurodegenerative Diseases; Reperfusio | 2021 |
Melatonin and its protective role in attenuating warm or cold hepatic ischaemia/reperfusion injury.
Topics: Antioxidants; Apoptosis; Graft Rejection; Humans; Liver; Melatonin; Mitochondria; Protective Agents; | 2021 |
Exosomes and Melatonin: Where Their Destinies Intersect.
Topics: Animals; Brain Diseases; Colitis; Exosomes; Humans; Kidney Diseases; Liver Diseases; Melatonin; Neop | 2021 |
Melatonin and mitochondrial function during ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Humans; Melatonin; Mitochondria; Reperfusion Injury | 2017 |
Melatonin application in targeting oxidative-induced liver injuries: A review.
Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Humans; Li | 2018 |
Hibernation-Based Approaches in the Treatment of Hemorrhagic Shock.
Topics: Animals; Hibernation; Humans; Hydrogen Sulfide; Melatonin; Reperfusion Injury; Shock, Hemorrhagic | 2018 |
A review of melatonin in hepatic ischemia/reperfusion injury and clinical liver disease.
Topics: Antioxidants; Endothelium; Humans; Liver; Liver Diseases; Melatonin; Mitochondria; Reperfusion Injur | 2014 |
Oxidative and inflammatory biomarkers of ischemia and reperfusion injuries.
Topics: Angioplasty, Balloon, Coronary; Animals; Antioxidants; Disease Models, Animal; Female; Humans; Infla | 2015 |
Novel role of microRNAs in renal ischemia reperfusion injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Erythropoietin; Humans; Melatonin; Mice; MicroRNAs; Rats; R | 2015 |
Melatonin role preventing steatohepatitis and improving liver transplantation results.
Topics: Animals; Antioxidants; Fatty Liver; Humans; Liver; Liver Transplantation; Melatonin; Oxidative Stres | 2016 |
Potential benefits of melatonin in organ transplantation: a review.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Female; Graft Rejection; Humans; Male; Melatonin; O | 2016 |
Chapter 16: Melatonin and nerve regeneration.
Topics: Animals; Humans; Melatonin; Nerve Regeneration; Optic Nerve; Pain; Peripheral Nerve Injuries; Periph | 2009 |
Pharmacological strategies against cold ischemia reperfusion injury.
Topics: Cold Ischemia; Cold Temperature; Endothelin Receptor Antagonists; Humans; Intercellular Signaling Pe | 2010 |
[Melatonin: its role in the system of neurohumoral regulation in man. Part 2].
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Anticarcinogenic Agents; Blood Pressure; Cardiova | 2011 |
Cardioprotective effect of melatonin against ischaemia/reperfusion damage.
Topics: Calcium; Cardiotonic Agents; Humans; Melatonin; Mitochondria; Myocardium; Receptors, Melatonin; Repe | 2013 |
The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion.
Topics: Animals; Humans; Melatonin; Neurons; Neuroprotective Agents; Reperfusion Injury | 2003 |
When melatonin gets on your nerves: its beneficial actions in experimental models of stroke.
Topics: Animals; Antioxidants; DNA Damage; Humans; Lipid Peroxidation; Melatonin; Models, Biological; Models | 2005 |
Role of melatonin in neurodegenerative diseases.
Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Brain Chemistry; Brain Injuries; Free Radical Scave | 2005 |
Physiological ischemia/reperfusion phenomena and their relation to endogenous melatonin production: a hypothesis.
Topics: Animals; Animals, Newborn; Arousal; Diving; Hibernation; Humans; Infant, Newborn; Male; Melatonin; P | 2005 |
Protective effects of melatonin in experimental free radical-related ocular diseases.
Topics: Antioxidants; Cataract; Eye Diseases; Glaucoma; Humans; Keratitis; Melatonin; Ocular Physiological P | 2006 |
Melatonin and ischemia-reperfusion injury of the brain.
Topics: Animals; Brain; Brain Ischemia; Humans; Melatonin; Reperfusion Injury | 2008 |
Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage.
Topics: Animals; Antioxidants; Free Radical Scavengers; Free Radicals; Head Injuries, Closed; Humans; Melato | 2007 |
Melatonin as modulator of pancreatic enzyme secretion and pancreatoprotector.
Topics: Acute Disease; Amylases; Animals; Ceruletide; Cholecystokinin; Free Radical Scavengers; Gastrointest | 2007 |
Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis.
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Endothelium, Vascular; Humans; In Vitro Techniques; Mela | 2000 |
Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury.
Topics: Animals; Free Radical Scavengers; Humans; Inflammation; Melatonin; Models, Biological; Poly(ADP-ribo | 2001 |
6 trials available for melatonin and Reperfusion Injury
| Article | Year |
|---|---|
Effect of Preoperative Administration of Oral Melatonin on Pneumatic Tourniquet-Induced Ischemia-Reperfusion Injury in Orthopedic Surgery of Lower Extremities: A Randomized Clinical Trial.
Topics: Humans; Lower Extremity; Melatonin; Orthopedic Procedures; Reperfusion Injury; Superoxide Dismutase; | 2022 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
The effect of oral melatonin on renal ischemia-reperfusion injury in transplant patients: A double-blind, randomized controlled trial.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Anti-Inflammatory Agents; Antioxidants; Double-Blind Method; Fem | 2019 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Animals; Blotting, Western; Brain Ischemia; Enzyme-Linked Immunosorbent Ass | 2018 |
Intracoronary and systemic melatonin to patients with acute myocardial infarction: protocol for the IMPACT trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antioxidants; Clinical Protocols; Double-Blind Method; D | 2014 |
212 other studies available for melatonin and Reperfusion Injury
| Article | Year |
|---|---|
Synthesis and characterization of novel indole derivatives reveal improved therapeutic agents for treatment of ischemia/reperfusion (I/R) injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Capillary Permeability; Free Radical | 2010 |
New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury.
Topics: Animals; Brain Ischemia; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Line, Tumor; Dih | 2014 |
Protective role of melatonin and spirulina in aortic occlusion-reperfusion model in rats.
Topics: Animals; Antioxidants; Female; Ischemia; Male; Melatonin; Rats; Rats, Wistar; Reperfusion; Reperfusi | 2022 |
Melatonin ameliorates cerebral ischemia-reperfusion injury in diabetic mice by enhancing autophagy via the SIRT1-BMAL1 pathway.
Topics: Animals; Antioxidants; ARNTL Transcription Factors; Autophagy; Brain Ischemia; Diabetes Mellitus, Ex | 2021 |
Melatonin attenuates reactive astrogliosis and glial scar formation following cerebral ischemia and reperfusion injury mediated by GSK-3β and RIP1K.
Topics: Animals; Brain Ischemia; Gliosis; Glycogen Synthase Kinase 3 beta; Inflammation; Male; Melatonin; Ne | 2022 |
Melatonin protects H9c2 cardiomyoblasts from oxygen-glucose deprivation and reperfusion-induced injury by inhibiting Rac1/JNK/Foxo3a/Bim signaling pathway.
Topics: Apoptosis; Glucose; Humans; Melatonin; Myocytes, Cardiac; Oxygen; rac1 GTP-Binding Protein; Reperfus | 2022 |
Influence of Melatonin on Behavioral and Neurological Function of Rats with Focal Cerebral Ischemia-Reperfusion Injury via the JNK/FoxO3a/Bim Pathway.
Topics: Animals; Bcl-2-Like Protein 11; Behavior, Animal; Brain; Brain Ischemia; Computational Biology; Dise | 2022 |
[Electroacupuncture ameliorates ischemic injury in cerebral ischemia-reperfusion rats by regulating endogenous melatonin and inhibiting the activation of astrocytes].
Topics: Animals; Astrocytes; Brain Ischemia; Electroacupuncture; Melatonin; Rats; Rats, Sprague-Dawley; Repe | 2022 |
Electroacupuncture Ameliorates Cognitive Impairment Through the Inhibition of NLRP3 Inflammasome Activation by Regulating Melatonin-Mediated Mitophagy in Stroke Rats.
Topics: Animals; Brain Ischemia; Cognitive Dysfunction; Electroacupuncture; Infarction, Middle Cerebral Arte | 2022 |
Protective effect of melatonin as an antioxidant in the intestine of rats with superior mesenteric arterial occlusion.
Topics: Animals; Antioxidants; Intestines; Ischemia; Male; Malondialdehyde; Melatonin; Rats; Rats, Wistar; R | 2022 |
Effect of melatonin on electrical impedance and biomarkers of damage in a gastric ischemia/reperfusion model.
Topics: Animals; Biomarkers; Critical Illness; Electric Impedance; Gastric Mucosa; Ischemia; Male; Melatonin | 2022 |
Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis.
Topics: Acute Kidney Injury; Animals; Ferroptosis; Folic Acid; Hypoxia; Melatonin; Mice; NF-E2-Related Facto | 2022 |
Melatonin Alleviates the Oxygen-Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2 (NFE2L2)/ROS/NLRP3 Pathway.
Topics: Animals; Glucose; Hair Cells, Auditory; Melatonin; Mice; NF-E2-Related Factor 2; NLR Family, Pyrin D | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin.
Topics: Animals; Liver; Male; Melatonin; Microplastics; Plastics; Rats; Rats, Wistar; Reperfusion Injury | 2023 |
Effect of limb remote ischemic preconditioning on the endogenous melatonin signaling in patients undergoing hepatectomy: A pilot prospective study.
Topics: Hepatectomy; Humans; Ischemic Preconditioning; Melatonin; Prospective Studies; Reperfusion Injury | 2023 |
The additive effects of nicotinamide mononucleotide and melatonin on mitochondrial biogenesis and fission/fusion, autophagy, and microRNA-499 in the aged rat heart with reperfusion injury.
Topics: Animals; Autophagy; Male; Melatonin; MicroRNAs; Myocardial Reperfusion Injury; Nicotinamide Mononucl | 2023 |
[Electroacupuncture alleviates cerebral ischemia injury in rats by regulating melatonin-NLRP3 and inhibiting pyroptosis].
Topics: Animals; Brain Injuries; Brain Ischemia; Caspase 1; Cerebral Infarction; Electroacupuncture; Melaton | 2023 |
Melatonin attenuates lung ischemia-reperfusion injury through SIRT3 signaling-dependent mitophagy in type 2 diabetic rats.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lung; Melatonin; Mit | 2023 |
Melatonin modulates the aggravation of pyroptosis, necroptosis, and neuroinflammation following cerebral ischemia and reperfusion injury in obese rats.
Topics: Animals; Brain Ischemia; Inflammation; Male; Melatonin; Necroptosis; Neuroinflammatory Diseases; Obe | 2023 |
Melatonin Attenuates Cerebral Ischemia/Reperfusion Injury through Inducing Autophagy.
Topics: Animals; Autophagy; Beclin-1; Brain Injuries; Brain Ischemia; Caspase 3; Infarction; Infarction, Mid | 2023 |
Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Diabetes Mellitus, Type 1; Hyperglycemia; Infarction, | 2023 |
Multi-parametric MRI assessment of melatonin regulating the polarization of microglia in rats after cerebral ischemia/reperfusion injury.
Topics: Amides; Animals; Brain Ischemia; Cerebral Infarction; Magnetic Resonance Imaging; Melatonin; Microgl | 2023 |
Melatonin regulates neuroinflammation ischemic stroke damage through interactions with microglia in reperfusion phase.
Topics: Animals; Brain Ischemia; Inflammation; Ischemia; Male; Melatonin; Microglia; Neuroimmunomodulation; | 2019 |
Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation.
Topics: Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Male; Melatonin; Mice; Mice, | 2019 |
The Role of Melatonin in Electroacupuncture Alleviating Lung Injury Induced by Limb Ischemia-Reperfusion in Rabbits.
Topics: Animals; Disease Models, Animal; Electroacupuncture; Lung Injury; Melatonin; Rabbits; Reperfusion; R | 2020 |
Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Cognitive Dysfunction; Cytokines; Intestinal Di | 2020 |
The circadian nuclear receptor RORα negatively regulates cerebral ischemia-reperfusion injury and mediates the neuroprotective effects of melatonin.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Cerebral Infarction; Circadian Rhythm; Disease Mod | 2020 |
Melatonin pretreatment alleviates renal ischemia-reperfusion injury by promoting autophagic flux via TLR4/MyD88/MEK/ERK/mTORC1 signaling.
Topics: Animals; Autophagy; Extracellular Signal-Regulated MAP Kinases; Female; Inflammation; Kidney; Mechan | 2020 |
Combination therapy with melatonin, stem cells and extracellular vesicles is effective in limiting renal ischemia-reperfusion injury in a rat model.
Topics: Animals; Apoptosis; Female; Kidney; Kidney Diseases; Melatonin; Mesenchymal Stem Cells; Oxidative St | 2020 |
Melatonin Plays a Protective Role by Regulating miR-26a-5p-NRSF and JAK2-STAT3 Pathway to Improve Autophagy, Inflammation and Oxidative Stress of Cerebral Ischemia-Reperfusion Injury.
Topics: Animals; Apoptosis; Autophagy; Disease Models, Animal; Inflammation; Injections, Intravenous; Janus | 2020 |
Melatonin attenuates ovarian ischemia reperfusion injury in rats by decreasing oxidative stress index and peroxynitrite
Topics: Animals; Female; Melatonin; Ovarian Torsion; Ovary; Oxidative Stress; Peroxynitrous Acid; Rats; Rats | 2020 |
Octreotide and melatonin alleviate inflammasome-induced pyroptosis through inhibition of TLR4-NF-κB-NLRP3 pathway in hepatic ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Drug Therapy, Combination; Inflammasomes; Liver; Male; Melatonin; NF-kappa B; | 2021 |
Synergic effect of combined cyclosporin and melatonin protects the brain against acute ischemic reperfusion injury.
Topics: Animals; Apoptosis; Brain; Cell Line, Tumor; Cyclosporine; Disease Models, Animal; Drug Synergism; D | 2021 |
Melatonin Decreases Circulating Levels of Galectin-3 and Cytokines, Motor Activity, and Anxiety Following Acute Global Cerebral Ischemia in Male Rats.
Topics: Animals; Anxiety; Brain Ischemia; Cytokines; Galectin 3; Male; Melatonin; Motor Activity; Rats; Rats | 2021 |
Targeting autophagy to modulate hepatic ischemia/reperfusion injury: A comparative study between octreotide and melatonin as autophagy modulators through AMPK/PI3K/AKT/mTOR/ULK1 and Keap1/Nrf2 signaling pathways in rats.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Autophagy-Re | 2021 |
Exogenous melatonin alleviates hemorrhagic shock‑induced hepatic ischemic injury in rats by inhibiting the NF‑κB/IκBα signaling pathway.
Topics: Animals; Disease Models, Animal; Humans; Liver; Male; Melatonin; NF-kappa B; NF-KappaB Inhibitor alp | 2021 |
Melatonin attenuates hepatic ischemia-reperfusion injury in rats by inhibiting NF-κB signaling pathway.
Topics: Animals; Humans; Liver; Melatonin; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signa | 2021 |
Melatonin postconditioning ameliorates anoxia/reoxygenation injury by regulating mitophagy and mitochondrial dynamics in a SIRT3-dependent manner.
Topics: Animals; Apoptosis; Cell Line; Gene Silencing; Melatonin; Mitochondria; Mitochondrial Dynamics; Mito | 2021 |
Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Ischemia; Melatonin; Rats; Rats, Wistar; Reperfusion; Re | 2021 |
Melatonin Improves Reduced Activities of Membrane ATPases and Preserves Ultrastructure of Gray and White Matter in the Rat Brain Ischemia/Reperfusion Model.
Topics: Adenosine Triphosphatases; Animals; Brain Ischemia; Disease Models, Animal; Gray Matter; Melatonin; | 2021 |
Combined tacrolimus and melatonin effectively protected kidney against acute ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Animals; Antioxidants; Drug Therapy, Combination; Immunosuppressive Agents; Mal | 2021 |
Melatonin reshapes the mitochondrial network and promotes intercellular mitochondrial transfer via tunneling nanotubes after ischemic-like injury in hippocampal HT22 cells.
Topics: Animals; Brain Ischemia; Cell Line; Cell Membrane Structures; Hippocampus; Melatonin; Mice; Mitochon | 2021 |
Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway.
Topics: Animals; Apoptosis; Brain Edema; Brain Ischemia; Cell Line; Cell Survival; Chromones; Diabetes Melli | 2021 |
Combined melatonin-adipose derived mesenchymal stem cells therapy effectively protected the testis from testicular torsion-induced ischemia-reperfusion injury.
Topics: Animals; Humans; Male; Melatonin; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Reperfusion In | 2021 |
Melatonin attenuates lung ischaemia-reperfusion injury via inhibition of oxidative stress and inflammation.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Disease Models, Animal; I-kappa B Kinase; Inflammation; | 2018 |
Melatonin exhibits supportive effects on oxidants and anastomotic healing during intestinal ischemia/reperfusion injury.
Topics: Anastomosis, Surgical; Animals; Antioxidants; Female; Ileum; Male; Melatonin; Rats; Rats, Wistar; Re | 2018 |
Exogenous melatonin protects small-for-size liver grafts by promoting monocyte infiltration and releases interleukin-6.
Topics: Animals; Cells, Cultured; Flow Cytometry; Hepatectomy; Interleukin-6; Liver; Liver Transplantation; | 2018 |
The effects of zinc and melatonin on muscle ischaemi-reperfusion injury in rat.
Topics: Animals; Antioxidants; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Muscles; O | 2018 |
Cardioprotective Effects of Melatonin in Reperfusion Injury.
Topics: Antioxidants; Humans; Melatonin; Myocardial Reperfusion Injury; Reperfusion Injury | 2018 |
Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress.
Topics: Activating Transcription Factor 4; Animals; Brain; eIF-2 Kinase; Endoplasmic Reticulum Stress; Eukar | 2018 |
Combined effects of melatonin and topical hypothermia on renal ischemia-reperfusion injury in rats.
Topics: Animals; Combined Modality Therapy; Disease Models, Animal; Hypothermia, Induced; Kidney; Male; Malo | 2018 |
Therapeutic effects of melatonin on cerebral ischemia reperfusion injury: Role of Yap-OPA1 signaling pathway and mitochondrial fusion.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Brain Ischemia; Cell Cycle Proteins; Ce | 2019 |
Effects of melatonin on acute brain reperfusion stress: role of Hippo signaling pathway and MFN2-related mitochondrial protection.
Topics: Acute Disease; Animals; Apoptosis; Brain; Cell Line, Tumor; Energy Metabolism; Gene Knockdown Techni | 2019 |
Transcriptional Regulation of Antioxidant Enzymes Activity and Modulation of Oxidative Stress by Melatonin in Rats Under Cerebral Ischemia / Reperfusion Conditions.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Free Radicals; Ischemia; Male; Melatonin; Nerve Tissue | 2019 |
Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis.
Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Gene Expression Regulation; Intercellular Si | 2019 |
Effect of melatonin on torsion and reperfusion induced pathogenesis of rat uterus.
Topics: Animals; Antioxidants; Apoptosis; Female; Male; Malondialdehyde; Melatonin; Rats, Wistar; Reperfusio | 2019 |
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Endoplasmic Reticulum Stress; Fatty Liver; Histoc | 2013 |
Use of thiamine pyrophosphate to prevent infertility developing in rats undergoing unilateral ovariectomy and with ischemia reperfusion induced in the contralateral ovary.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Infertility, Female; Melatonin; Ovarian Disea | 2013 |
Melatonin inhibits mTOR-dependent autophagy during liver ischemia/reperfusion.
Topics: Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Calpain; Hepatocytes; Liver; Melatonin; | 2014 |
Effect of a combined treatment with erythropoietin and melatonin on renal ischemia reperfusion injury in male rats.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Drug T | 2014 |
Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia.
Topics: Animals; Antioxidants; Apoptosis; Aquaporin 4; Blotting, Western; Brain Edema; Brain Ischemia; Calci | 2014 |
Protective effect of melatonin on infrarenal aortic occlusion: this effect is related to anti-inflammatory effect and antioxidant effect.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Arterial Occlusive Diseases; Blood Urea Nitr | 2014 |
Evaluation of renal protection from high doses of melatonin in an experimental model of renal ischemia and reperfusion in hyperglycemic rats.
Topics: Animals; Dose-Response Relationship, Drug; Hyperglycemia; Kidney; Male; Melatonin; Rats; Rats, Wista | 2014 |
Alterations in the time course of expression of the Nox family in the brain in a rat experimental cerebral ischemia and reperfusion model: effects of melatonin.
Topics: Animals; Blotting, Western; Brain; Brain Ischemia; In Situ Nick-End Labeling; Male; Melatonin; Membr | 2014 |
[The role of NO-dependent mechanisms in melatonin antioxidant activity during hepatic ischemia-reperfusion in rats].
Topics: alpha-Tocopherol; Animals; Antioxidants; Catalase; Hemoglobins; Liver; Male; Melatonin; NG-Nitroargi | 2014 |
The beneficial effect of melatonin in brain endothelial cells against oxygen-glucose deprivation followed by reperfusion-induced injury.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Brain; Cell Line; Endothelial Cells; G | 2014 |
Melatonin attenuates intestinal ischemia--reperfusion-induced lung injury in rats by upregulating N-myc downstream-regulated gene 2.
Topics: Animals; Cytokines; Intestines; Lung; Lung Injury; Male; Malondialdehyde; Melatonin; Nerve Tissue Pr | 2015 |
Effects of melatonin on the serum levels of pro-inflammatory cytokines and tissue injury after renal ischemia reperfusion in rats.
Topics: Animals; Antioxidants; Biological Factors; Inflammation; Interleukin-6; Kidney; Kidney Diseases; Lip | 2015 |
The effect of melatonin on bacterial translocation following ischemia/reperfusion injury in a rat model of superior mesenteric artery occlusion.
Topics: Animals; Antioxidants; Bacterial Translocation; Male; Melatonin; Mesenteric Artery, Superior; Mesent | 2015 |
The Effect of Circadian Melatonin Levels on Inflammation and Neurocognitive Functions Following Coronary Bypass Surgery.
Topics: Circadian Rhythm; Cognition Disorders; Coronary Artery Bypass; Female; Humans; Inflammation; Interce | 2015 |
Protective effect of melatonin-supported adipose-derived mesenchymal stem cells against small bowel ischemia-reperfusion injury in rat.
Topics: Adipose Tissue; Allografts; Animals; Gene Expression Regulation; Inflammation; Intestine, Small; Mal | 2015 |
Melatonin modulates endoplasmic reticulum stress and Akt/GSK3-beta signaling pathway in a rat model of renal warm ischemia reperfusion.
Topics: Animals; Blotting, Western; Creatinine; Endoplasmic Reticulum Stress; Extracellular Signal-Regulated | 2015 |
Combined melatonin and exendin-4 therapy preserves renal ultrastructural integrity after ischemia-reperfusion injury in the male rat.
Topics: Animals; Cadherins; Calcium-Binding Proteins; Cell Adhesion Molecules; Exenatide; Kidney; Male; Matr | 2015 |
Melatonin prevents lung injury induced by hepatic ischemia-reperfusion through anti-inflammatory and anti-apoptosis effects.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Cytoki | 2015 |
Combination effect of melatonin and dexamethasone on liver ischemia/reperfusion injury.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Dexamethasone; Male; Melatonin; Protecti | 2016 |
Melatonin pretreatment enhances the therapeutic effects of exogenous mitochondria against hepatic ischemia-reperfusion injury in rats through suppression of mitochondrial permeability transition.
Topics: Animals; Apoptosis; Gene Expression Regulation; Liver; Liver Diseases; Male; Melatonin; Mitochondria | 2016 |
EFFECT OF THREE-WEEK ZINC AND MELATONIN SUPPLEMENTATION ON THE OXIDANT-ANTIOXIDANT SYSTEM IN EXPERIMENTAL RENAL ISCHEMIA-REPERFUSION IN RATS.
Topics: Animals; Antioxidants; Free Radicals; Kidney; Male; Malondialdehyde; Melatonin; Oxidation-Reduction; | 2015 |
Enhanced protection against renal ischemia-reperfusion injury with combined melatonin and exendin-4 in a rodent model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Blood Urea Nitrogen; Creatin | 2016 |
Blue light reduces organ injury from ischemia and reperfusion.
Topics: Animals; Color; Color Therapy; Corticosterone; Dose-Response Relationship, Radiation; HMGB1 Protein; | 2016 |
The protective effect of melatonin on remote organ liver ischemia and reperfusion injury following aortic clamping.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Abdominal; Aspartate A | 2016 |
Effects of melatonin and metformin co-administration on testicular ischemia/reperfusion injury in rats.
Topics: Animals; Antioxidants; Drug Therapy, Combination; Male; Melatonin; Metformin; Random Allocation; Rat | 2016 |
Combination Anti-Apoptotic Effect of Erythropoietin and Melatonin on Ischemia Reperfusion-Induced Renal Injury in Rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Epoetin Alfa; Erythropoietin; Glutathione Per | 2016 |
The effects of melatonin and colchicine on ischemia-reperfusion injury in experimental rat testicular torsion model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colchicine; Male; Melatonin; Random All | 2017 |
Protective roles of nanomelatonin in cerebral ischemia-reperfusion of aged brain: Matrixmetalloproteinases as regulators.
Topics: Aging; Animals; Antioxidants; Blood-Brain Barrier; Brain Ischemia; Disease Models, Animal; Female; M | 2017 |
The protective effects of carnosine and melatonin in ischemia-reperfusion injury in the rat liver.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carnosine; Female; Glutath | 2009 |
[Total hepatic ischemia-reperfusion-induced lung injury in rats and protective effects of melatonin].
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Liver; Lung Injury; Male; Melatonin; Random All | 2008 |
Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Diabetes Mellitu | 2008 |
Melatonin decreases matrix metalloproteinase-9 activation and expression and attenuates reperfusion-induced hemorrhage following transient focal cerebral ischemia in rats.
Topics: Animals; Blotting, Western; Brain; Brain Infarction; Cerebral Hemorrhage; Enzyme Activation; Gene Ex | 2008 |
Melatonin regulates nitric oxide synthase expression in ischemic brain injury.
Topics: Animals; Blotting, Western; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Isoenzymes; | 2008 |
[Involvement of melatonin in the adjusting effect of electroacupuncture in resisting oxygen stress in cerebral ischemia-reperfusion injury rats].
Topics: Animals; bcl-2-Associated X Protein; Electroacupuncture; Gene Expression; Male; Melatonin; Oxidation | 2008 |
Effects of melatonin on spermatogenesis and testicular ischemia-reperfusion injury after unilateral testicular torsion-detorsion.
Topics: Animals; Antioxidants; Biomarkers; Drug Evaluation, Preclinical; Free Radical Scavengers; Glutathion | 2008 |
Melatonin protects liver from intestine ischemia reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Intercellular Adhesion Mol | 2008 |
Effect of melatonin on epididymal sperm quality after testicular ischemia/reperfusion in rats.
Topics: Animals; Disease Models, Animal; Epididymis; Injections, Intraperitoneal; Male; Melatonin; Rats; Rat | 2010 |
Primary graft dysfunction in lung transplantation: the role of CD26/dipeptidylpeptidase IV and vasoactive intestinal peptide.
Topics: Animals; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Follow-Up Studies; Graft Surviv | 2009 |
Melatonin and 1400 W ameliorate both intestinal and remote organ injury following mesenteric ischemia/reperfusion.
Topics: Amidines; Animals; Antioxidants; Benzylamines; Enzyme Inhibitors; Glutathione Peroxidase; Glutathion | 2009 |
Cellular and vascular changes in the retina of neonatal rats after an acute exposure to hypoxia.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Blotting, Western; Capillary Permeability; Fluor | 2009 |
Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation.
Topics: Analysis of Variance; Animals; Apoptosis; Caspase 3; Histocytochemistry; Kaplan-Meier Estimate; Kidn | 2009 |
Ischemia-reperfusion injury and melatonin.
Topics: Humans; Melatonin; Reperfusion Injury | 2009 |
Comparison of the efficacy of melatonin and 1400W on renal ischemia/reperfusion injury: a role for inhibiting iNOS.
Topics: Amidines; Animals; Antioxidants; Benzylamines; Disease Models, Animal; Enzyme Inhibitors; Kidney; Ki | 2009 |
Therapeutic effects of maternal melatonin administration on ischemia/reperfusion-induced oxidative cerebral damage in neonatal rats.
Topics: Animals; Animals, Newborn; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Female; | 2010 |
Melatonin protects N2a against ischemia/reperfusion injury through autophagy enhancement.
Topics: Animals; Autophagy; Cell Hypoxia; Cell Line, Tumor; Melatonin; Mice; Neuroblastoma; Neuroprotective | 2010 |
Melatonin attenuates I/R-induced mitochondrial dysfunction in skeletal muscle.
Topics: Animals; Antioxidants; Benzimidazoles; Carbocyanines; Cytochromes c; Fluorescent Dyes; Male; Melaton | 2011 |
Arylalkylamine N-acetyltransferase (AANAT) is expressed in astrocytes and melatonin treatment maintains AANAT in the gerbil hippocampus induced by transient cerebral ischemia.
Topics: Animals; Arylalkylamine N-Acetyltransferase; Astrocytes; CA1 Region, Hippocampal; Cell Death; Gerbil | 2010 |
Evaluation of effects of s-methyl isothiourea and melatonin on intestinal ischemia/reperfusion injury in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Glutath | 2010 |
Melatonin inhibits postischemic matrix metalloproteinase-9 (MMP-9) activation via dual modulation of plasminogen/plasmin system and endogenous MMP inhibitor in mice subjected to transient focal cerebral ischemia.
Topics: Animals; Behavior, Animal; Brain; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fib | 2010 |
Proteomic identification of proteins differentially expressed by melatonin in hepatic ischemia-reperfusion injury.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Blotting, Western; | 2010 |
Protective effects of melatonin on testicular torsion/detorsion-induced ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Immunohistochemistry; In Situ Nick-End Labeling; Male; Melatonin; | 2010 |
Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke.
Topics: Animals; Brain Infarction; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Infant, Newborn; | 2011 |
[Protective effects of melatonin on ischemia-reperfusion injury of skeletal muscle].
Topics: Animals; Extremities; Male; Melatonin; Muscle, Skeletal; Rats; Rats, Wistar; Reactive Oxygen Species | 2010 |
Pre-treatment of adrenomedullin suppresses cerebral edema caused by transient focal cerebral ischemia in rats detected by magnetic resonance imaging.
Topics: Adrenomedullin; Animals; Brain; Brain Edema; Infarction, Middle Cerebral Artery; Magnetic Resonance | 2011 |
Melatonin protects steatotic and nonsteatotic liver grafts against cold ischemia and reperfusion injury.
Topics: Animals; Fatty Liver; Liver; Male; Melatonin; Nitric Oxide; Oxidative Stress; Rats; Rats, Zucker; Re | 2011 |
Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Interleukin-6; JNK Mitogen-Ac | 2011 |
Estradiol worsens the syndrome of ischemia-reperfusion injury in an experimental lung transplantation model.
Topics: Animals; Antioxidants; Chi-Square Distribution; Deferoxamine; Disease Models, Animal; Estradiol; Gra | 2011 |
Melatonin prevents hepatic injury-induced decrease in Akt downstream targets phosphorylations.
Topics: 14-3-3 Proteins; Animals; Antioxidants; Apoptosis; bcl-Associated Death Protein; Dose-Response Relat | 2011 |
Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Vesicular Transport; Animals; Antioxidants; Cell N | 2012 |
The hormone melatonin stimulates renoprotective effects of "early outgrowth" endothelial progenitor cells in acute ischemic kidney injury.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Movement; Cells, Cultured; Endothelial C | 2012 |
Protective effect of melatonin on liver ischemia-reperfusion induced pulmonary microvascular injury in rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Capillary Permeability; Cytoprotection; Disease Models, An | 2012 |
Liver reperfusion-induced decrease in dynamic compliance and increase in airway resistance are ameliorated by preischemic treatment with melatonin through scavenging hydroxyl radicals in rat lungs.
Topics: Acute Lung Injury; Airway Resistance; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bi | 2012 |
Preischemic treatment with melatonin attenuates liver reperfusion-induced impairment of cardiac function.
Topics: Animals; Antioxidants; Biomarkers; Cardiac Catheterization; Creatine Kinase, MB Form; Disease Models | 2012 |
Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin.
Topics: Age Factors; Animals; Interleukin-10; Interleukin-1beta; Liver; Male; Melatonin; NF-kappa B p50 Subu | 2012 |
Effects of melatonin on testis histology, oxidative stress and spermatogenesis after experimental testis ischemia-reperfusion in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Male; Malondialdehyde; Melatonin; Oxidative Stress; R | 2012 |
Melatonin with 1,25-dihydroxyvitamin D3 protects against apoptotic ischemia-reperfusion injury in the rat kidney.
Topics: Animals; Antioxidants; Apoptosis; Calcitriol; Caspase 3; Kidney; Kidney Diseases; Kidney Tubules; Ma | 2012 |
Commentary on: Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin.
Topics: Animals; Liver; Male; Melatonin; Reperfusion Injury; Transcriptional Activation | 2013 |
Comparison of melatonin and ozone in the prevention of reperfusion injury following unilateral testicular torsion in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Glutathione; Inhibins; Injections, Intraperitoneal; M | 2012 |
Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin.
Topics: Animals; Liver; Male; Melatonin; Reperfusion Injury; Transcriptional Activation | 2013 |
Melatonin treatment improves adipose-derived mesenchymal stem cell therapy for acute lung ischemia-reperfusion injury.
Topics: Adipose Tissue; Adiposity; Animals; Blotting, Western; Immunohistochemistry; Male; Melatonin; Mesenc | 2013 |
Melatonin treatment protects liver of Zucker rats after ischemia/reperfusion by diminishing oxidative stress and apoptosis.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Caspase 9; DNA Fragmentation; Gene Express | 2013 |
Vascular endothelial cells and dysfunctions: role of melatonin.
Topics: Atherosclerosis; Diabetes Mellitus; Endothelial Cells; Humans; Hypertension; Melatonin; Nicotine; Re | 2013 |
[Effect of pretreatment with melatonin on the oxidative and inflammatory damage induced by hepatic ischemia/reperfusion in Zucker rats].
Topics: Age Factors; Animals; Inflammation; Liver; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Rats, Zu | 2011 |
Protective effect of melatonin and 1,25-dihydroxyvitamin D3 on renal ischemia-reperfusion injury in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Calcitriol; Drug Evaluation, Preclinical; Kidney; Male; | 2013 |
Effect of melatonin and nifedipine on some antioxidant enzymes and different energy fuels in the blood and brain of global ischemic rats.
Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Blood; Brain; Calcium Channel Blockers; Disease Models | 2002 |
Protective effect of melatonin and its precursor L-tryptophan on acute pancreatitis induced by caerulein overstimulation or ischemia/reperfusion.
Topics: Adjuvants, Immunologic; Animals; Ceruletide; Interleukin-10; Ischemia; Male; Melatonin; Pancreas; Pa | 2003 |
[The protective effects of melatonin on global cerebral ischemia-reperfusion injury in gerbils].
Topics: Animals; Brain Ischemia; Female; Gerbillinae; Hippocampus; Learning; Male; Melatonin; Memory; Motor | 2002 |
Melatonin treatment protects against ischemia/reperfusion-induced functional and biochemical changes in rat urinary bladder.
Topics: Animals; Antioxidants; Carbachol; Cholinergic Agonists; Glutathione; Lipid Peroxidation; Male; Malon | 2003 |
Altered neutrophil apoptosis activity is reversed by melatonin in liver ischemia-reperfusion.
Topics: Apoptosis; CD18 Antigens; Cells, Cultured; Cholecystectomy, Laparoscopic; Hepatectomy; Humans; Ische | 2003 |
Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion.
Topics: Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Caspase 3; Caspases; Creatinine; Enzyme Activ | 2003 |
Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Female; Free Radical Scavengers; Glutathione; Isc | 2003 |
The protective effects of physiological and pharmacological concentrations of melatonin on renal ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatine; Dose-Response Relationship, Drug; Free Radical | 2003 |
Protective effect of melatonin against mitochondrial injury induced by ischemia and reperfusion of rat liver.
Topics: Animals; Ischemia; Liver; Male; Melatonin; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Reperfus | 2003 |
Melatonin ameliorates oxidative organ damage induced by acute intra-abdominal compartment syndrome in rats.
Topics: Abdomen; Animals; Compartment Syndromes; Free Radical Scavengers; Glutathione; Ischemia; Lipid Perox | 2003 |
Protective effect of melatonin on experimental spinal cord ischemia.
Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Glutathione Peroxidase; Lipid Peroxidation; | 2003 |
The effects of melatonin and prostaglandin E1 analogue on experimental hepatic ischaemia reperfusion damage.
Topics: Alanine Transaminase; Alprostadil; Animals; Antioxidants; Aspartate Aminotransferases; Erythrocytes; | 2003 |
Neuroprotective effect of combination of poly (ADP-ribose) polymerase inhibitor and antioxidant in middle cerebral artery occlusion induced focal ischemia in rats.
Topics: Animals; Antioxidants; Benzamides; Brain Ischemia; Disease Models, Animal; Drug Combinations; Drug T | 2004 |
Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator.
Topics: Animals; Brain Ischemia; Caspase 3; Caspase Inhibitors; Cell Death; Coronary Disease; Corpus Striatu | 2004 |
Melatonin ameliorates renal ischemia/reperfusion injury.
Topics: Animals; Creatinine; Glutathione; Kidney; Lipid Peroxidation; Male; Melatonin; Necrosis; Nitric Oxid | 2004 |
Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin.
Topics: Animals; Apoptosis; Calcium Signaling; Cell Hypoxia; Corpus Striatum; Infarction, Middle Cerebral Ar | 2004 |
Melatonin in vivo prolongs cardiac allograft survival in rats.
Topics: Animals; Antioxidants; Graft Rejection; Graft Survival; Heart Transplantation; Immunoglobulin M; Imm | 2004 |
Melatonin does not prevent the protection of ischemic preconditioning in vivo despite its antioxidant effect against oxidative stress.
Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Free Radicals; Ischemic Preconditioning; Lipid Per | 2004 |
Pretreatment with melatonin exerts anti-inflammatory effects against ischemia/reperfusion injury in a rat middle cerebral artery occlusion stroke model.
Topics: Animals; Antioxidants; Brain; Cyclooxygenase 2; Disease Models, Animal; Glial Fibrillary Acidic Prot | 2004 |
Melatonin reduces torsion-detorsion injury in rat ovary: biochemical and histopathologic evaluation.
Topics: Animals; Antioxidants; Female; Glutathione; Malondialdehyde; Melatonin; Ovary; Rats; Reactive Oxygen | 2004 |
Beneficial effects of melatonin on reperfusion injury in rat sciatic nerve.
Topics: Animals; Axons; Cytoprotection; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Myelin Sheath; | 2004 |
Protective role of melatonin given either before ischemia or prior to reperfusion on intestinal ischemia-reperfusion damage.
Topics: Animals; Antioxidants; Catalase; Glutathione Peroxidase; Intestinal Mucosa; Intestines; Ischemia; Li | 2004 |
Maternally administered melatonin protects against ischemia and reperfusion-induced oxidative mitochondrial damage in premature fetal rat brain.
Topics: Animals; Antioxidants; Brain; Cell Respiration; Female; Fetus; Melatonin; Mitochondria; Oxidative St | 2004 |
The effects of melatonin on focal cerebral ischemia-reperfusion model.
Topics: Animals; Brain Ischemia; Cell Survival; Cerebral Cortex; Disease Models, Animal; Infarction, Middle | 2004 |
Protective effects of melatonin on myocardial ischemia/reperfusion induced infarct size and oxidative changes.
Topics: Animals; Cardiotonic Agents; Glutathione; Male; Malondialdehyde; Melatonin; Myocardial Infarction; O | 2005 |
Protective effect of melatonin on contractile activity and oxidative injury induced by ischemia and reperfusion of rat ileum.
Topics: Acetylcholine; Animals; Antioxidants; Dose-Response Relationship, Drug; Glutathione; Ileum; Male; Ma | 2005 |
Melatonin reduces bacterial translocation after intestinal ischemia-reperfusion injury.
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Intestines; Liver; Lung; Lymph Nodes; Male | 2004 |
Microcirculatory effects of melatonin in rat skeletal muscle after prolonged ischemia.
Topics: Adjuvants, Immunologic; Animals; Capillaries; Dilatation, Pathologic; Gene Expression Regulation, En | 2005 |
Protective effect of melatonin against ischemia/reperfusion-induced oxidative remote organ injury in the rat.
Topics: Animals; Antioxidants; Aorta, Abdominal; Glutathione; Ligation; Lipid Peroxidation; Liver Function T | 2005 |
Melatonin protects against ischemia/reperfusion injury in skeletal muscle.
Topics: Animals; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Muscle Fibers, Skeletal; | 2005 |
L-Arginine and melatonin interaction in rat intestinal ischemia--reperfusion.
Topics: Acetylcholine; Animals; Anticonvulsants; Arginine; Drug Synergism; Ileum; Male; Melatonin; Mesentery | 2005 |
Ischemia-reperfusion injury--antiarrhythmic effect of melatonin associated with reduced recovering of contractility.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Free Radical Scavengers; Ischemia; Male; Mela | 2005 |
Inhibition of mitochondria responsible for the anti-apoptotic effects of melatonin during ischemia-reperfusion.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cerebellum; Cytochromes c; Cytoplasm; DN | 2006 |
Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas.
Topics: Amylases; Animals; Apoptosis; Caspase 3; Caspases; Catalase; DNA Fragmentation; Glutathione; Glutath | 2006 |
Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Infarction, Middle Cerebral Artery; Intracranial Hemor | 2006 |
Melatonin protects against pressure ulcer-induced oxidative injury of the skin and remote organs in rats.
Topics: Administration, Topical; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitr | 2006 |
Does anti-oxidant prophylaxis with melatonin prevent adverse outcomes related to increased oxidative stress caused by laparoscopy in experimental rat model?
Topics: Animals; Antioxidants; Disease Models, Animal; Intestine, Small; Kidney; Laparoscopy; Liver; Male; M | 2006 |
The protective effect of melatonin on ischemia-reperfusion injury in the groin (inferior epigastric) flap model in rats.
Topics: Animals; Disease Models, Animal; Female; Glutathione; Malondialdehyde; Melatonin; Rats; Rats, Wistar | 2006 |
Melatonin attenuates renal ischemia-reperfusion injury in nitric oxide synthase inhibited rats.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Kidney; Male; Malondialdehyde; Melatonin; NG-Nit | 2006 |
Neuroprotective effect of melatonin on retinal ganglion cells in rats.
Topics: Animals; Cell Survival; Female; Melatonin; Microscopy, Fluorescence; Neuroprotective Agents; Random | 2006 |
Melatonin reduces infarction volume in a photothrombotic stroke model in the wild-type but not cyclooxygenase-1-gene knockout mice.
Topics: Animals; Brain; Brain Edema; Cerebral Infarction; Cerebrovascular Circulation; Cyclooxygenase 1; Dis | 2006 |
Melatonin decreases neurovascular oxidative/nitrosative damage and protects against early increases in the blood-brain barrier permeability after transient focal cerebral ischemia in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Evans Blue; Infarction, Middle Cerebral Artery; Ischemic Attack | 2006 |
Melatonin reduces ischemia/reperfusion-induced superoxide generation in arterial wall and cell death in skeletal muscle.
Topics: Animals; Apoptosis; Arteries; Male; Melatonin; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Reperfu | 2006 |
Comparison of 6-hydroxylmelatonin or melatonin in protecting neurons against ischemia/reperfusion-mediated injury.
Topics: Animals; Caspase 3; Cell Line, Tumor; Cell Membrane Permeability; Hydroxylation; Melatonin; Membrane | 2006 |
Melatonin abates liver ischemia/reperfusion injury by improving the balance between nitric oxide and endothelin.
Topics: Alanine Transaminase; Animals; Endothelins; Eosine Yellowish-(YS); Hematoxylin; L-Lactate Dehydrogen | 2006 |
Melatonin reduces ventricular arrhythmias and preserves capillary perfusion during ischemia-reperfusion events in cardiomyopathic hamsters.
Topics: Angiotensin II; Animals; Antioxidants; Arrhythmias, Cardiac; Arterioles; Capillary Permeability; Car | 2007 |
The effects of prophylactic zinc and melatonin application on experimental spinal cord ischemia-reperfusion injury in rabbits: experimental study.
Topics: Analysis of Variance; Animals; Antioxidants; Disease Models, Animal; Glutathione Peroxidase; Male; M | 2007 |
Protective effects of melatonin and N-acetylcysteine on hepatic injury in a rat cardiopulmonary bypass model.
Topics: Acetylcysteine; Animals; Apoptosis; Cardiopulmonary Bypass; Disease Models, Animal; Free Radical Sca | 2007 |
Melatonin protects from ischemia/reperfusion-induced renal injury in rats: this effect is not mediated by proinflammatory cytokines.
Topics: Animals; Creatine; Cytokines; Kidney; Male; Melatonin; Nitrogen; Oxidative Stress; Phenols; Plant Ex | 2007 |
The protective effects of melatonin and vitamin E against renal ischemia-reperfusion injury in rats.
Topics: Animals; Kidney; Male; Melatonin; Rats; Rats, Wistar; Reperfusion Injury; Vitamin E | 2007 |
Effect of melatonin on testicular ischemia/reperfusion injury in rats: is this effect related to the proinflammatory cytokines?
Topics: Animals; Antioxidants; Cytokines; Cytoprotection; Inflammation Mediators; Interleukin-1beta; Interle | 2008 |
Protective effects of chronic melatonin treatment against renal ischemia/reperfusion injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Kidney Diseases; Lipid Peroxidation; Male; M | 2007 |
Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver.
Topics: Animals; Apoptosis; Liver; Male; Melatonin; Necrosis; Oxidation-Reduction; Rats; Reperfusion Injury | 2008 |
Melatonin preserves fetal growth in rats by protecting against ischemia/reperfusion-induced oxidative/nitrosative mitochondrial damage in the placenta.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; DNA Damage; DNA-(Apurinic or Apyrimidinic Site | 2008 |
Melatonin protects from hepatic reperfusion injury through inhibition of IKK and JNK pathways and modification of cell proliferation.
Topics: Analysis of Variance; Animals; Cell Proliferation; Female; Flow Cytometry; I-kappa B Kinase; Immunoh | 2009 |
Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney.
Topics: Animals; Bone Marrow Cells; Cell Proliferation; Cell Survival; Fibroblast Growth Factor 2; Hepatocyt | 2008 |
Melatonin prevents ischemia reperfusion injury in hamster cheek pouch microcirculation.
Topics: Animals; Capillary Permeability; Cell Adhesion; Cheek; Cricetinae; Leukocytes; Male; Melatonin; Meso | 1996 |
Melatonin affords protection against gastric lesions induced by ischemia-reperfusion possibly due to its antioxidant and mucosal microcirculatory effects.
Topics: Animals; Antioxidants; Ethanol; Free Radicals; Gastric Mucosa; Luminescent Measurements; Male; Melat | 1997 |
Gastroprotective activity of melatonin and its precursor, L-tryptophan, against stress-induced and ischaemia-induced lesions is mediated by scavenge of oxygen radicals.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; DNA; Dose-Resp | 1997 |
Melatonin administration protects CA1 hippocampal neurons after transient forebrain ischemia in rats.
Topics: Analysis of Variance; Animals; Free Radical Scavengers; Hippocampus; Ischemic Attack, Transient; Mal | 1997 |
Melatonin protects against gastric ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Biomarkers; Female; Gastric Mucosa; Glutathione Peroxidase; Injections, Intra | 1997 |
The role of melatonin and L-tryptophan in prevention of acute gastric lesions induced by stress, ethanol, ischemia, and aspirin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; DNA; Dose-Response Relatio | 1997 |
Ischemia/reperfusion-induced arrhythmias in the isolated rat heart: prevention by melatonin.
Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Ascorbic Acid; Dose-Response Relationship, Drug; Free R | 1998 |
Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Brain; Brain Ischemia; Deoxyguanosine; DNA; DNA Damage; Female | 1999 |
Melatonin decreases production of hydroxyl radical during cerebral ischemia-reperfusion.
Topics: Animals; Brain Ischemia; Free Radical Scavengers; Gentisates; Hydroxyl Radical; Male; Melatonin; Rat | 1997 |
Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Chemotaxis, Leukocyte; Endothelium, Vascular; Free Radical Scavengers; Ileal Diseases; Immu | 2000 |
Protective effect of melatonin on injuried cerebral neurons is associated with bcl-2 protein over-expression.
Topics: Animals; bcl-2-Associated X Protein; Brain; Brain Ischemia; Male; Melatonin; Neurons; Neuroprotectiv | 1999 |
Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia.
Topics: Animals; Brain Ischemia; Cell Death; Cell Survival; Cerebral Infarction; Free Radical Scavengers; Gl | 2000 |
The role of melatonin in prevention of intestinal ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Injections, Intraperitoneal; Intestinal Mucosa; Intestines; Lipid Peroxidatio | 2000 |
Protective effects of melatonin in ischemic brain injury.
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Free Radical Scaveng | 2000 |
Protective effect of melatonin on antioxidative system in experimental ischemia-reperfusion of rat small intestine.
Topics: Animals; Antioxidants; Copper; Erythrocytes; Glutathione Peroxidase; Histocytochemistry; Intestine, | 2000 |
Melatonin protects against ischaemic-reperfusion myocardial damage.
Topics: Aniline Compounds; Animals; Calcium; Cells, Cultured; Fluoresceins; Fluorescent Dyes; Heart Ventricl | 2001 |
Mechanisms involved in gastric protection of melatonin against oxidant stress by ischemia-reperfusion in rats.
Topics: Animals; Antioxidants; Female; Free Radical Scavengers; Gastric Mucosa; Glutathione; Glutathione Red | 2001 |
Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain.
Topics: Adenosine Diphosphate; Animals; Brain; Brain Injuries; Female; Fetus; Melatonin; Oxidative Stress; O | 2001 |
Melatonin protects against oxidative mitochondrial damage induced in rat placenta by ischemia and reperfusion.
Topics: Adenosine Diphosphate; Animals; Female; Fetal Growth Retardation; Humans; Melatonin; Mitochondria; O | 2001 |
Effect of exogenous melatonin on hepatic energetic status during ischemia/reperfusion: possible role of tumor necrosis factor-alpha and nitric oxide.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotr | 2001 |
Effect of melatonin on ischemia reperfusion injury induced by middle cerebral artery occlusion in rats.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Glutathione; Infarction, Middle Cerebral Artery; Injec | 2001 |
Melatonin attenuates posttransplant lung ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Free Radical Scavengers; Lipid Peroxidation; Lung Transplantation; Melatonin; | 2002 |
The effects of melatonin on ischemia-reperfusion induced changes in rat corpus cavernosum.
Topics: Acetylcholine; Animals; Antioxidants; Free Radical Scavengers; In Vitro Techniques; Lipid Peroxidati | 2002 |
Effects of melatonin on noncardiogenic pulmonary edema secondary to adnexial ischemia-reperfusion in guinea pig.
Topics: Adnexal Diseases; Animals; Antioxidants; Female; Guinea Pigs; Lung; Malondialdehyde; Melatonin; Ovar | 2002 |
The protective effect of melatonin on renal ischemia-reperfusion injury in the rat.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Glutathione; Kidney; Male; Malondialdehyde; Melatonin; Oxi | 2002 |
Melatonin protects the heart against both ischemia/reperfusion injury and chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Doxorubicin; Heart; Humans; Melatonin; Myocardial Ischemia; Reperfus | 2002 |