melatonin has been researched along with REM Sleep Behavior Disorder in 39 studies
REM Sleep Behavior Disorder: A disorder characterized by episodes of vigorous and often violent motor activity during REM sleep (SLEEP, REM). The affected individual may inflict self injury or harm others, and is difficult to awaken from this condition. Episodes are usually followed by a vivid recollection of a dream that is consistent with the aggressive behavior. This condition primarily affects adult males. (From Adams et al., Principles of Neurology, 6th ed, p393)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin is recommended as a first-line treatment in isolated REM sleep behavior disorder (iRBD), although no large patient group has been reported." | 8.02 | Treatment of isolated REM sleep behavior disorder using melatonin as a chronobiotic. ( Bes, F; Kunz, D; Stotz, S, 2021) |
| "To evaluate changes in the expression of clock genes and melatonin levels in patients with idiopathic REM sleep behavior disorder (RBD) as a potential early stage of synucleinopathies." | 7.88 | Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder. ( Bartoš, A; Bendová, Z; Bušková, J; Červená, K; Dudysová, D; Kopřivová, J; Miletínová, E; Skálová, K; Škrabalová, J; Šonka, K; Weissová, K, 2018) |
| "Melatonin also has a favorable safety and tolerability profile over clonazepam with limited potential for drug-drug interactions, an important consideration especially in elderly individuals with RBD receiving polypharmacy." | 6.52 | Melatonin therapy for REM sleep behavior disorder: a critical review of evidence. ( Boeve, BF; Leung, JG; McGrane, IR; St Louis, EK, 2015) |
| "Clonazepam has been the first-line therapy for many years, with 2 large case series reporting efficacy with few side effects in the majority of patients." | 5.35 | Drug treatment of REM sleep behavior disorder: the use of drug therapies other than clonazepam. ( Anderson, KN; Shneerson, JM, 2009) |
| "Clonazepam has been considered the treatment of choice for RBD." | 5.32 | Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients. ( Boeve, BF; Ferman, TJ; Silber, MH, 2003) |
| "A MEDLINE search (1977-April 2007) using the terms REM sleep behavior disorder, narcolepsy, parkinsonian disorders, levodopa, dopamine agonists, clonazepam, benzodiazepines, and melatonin was used to retrieve relevant articles." | 4.84 | Rapid eye movement sleep behavior disorder. ( Gugger, JJ; Wagner, ML, 2007) |
| "Melatonin is recommended as a first-line treatment in isolated REM sleep behavior disorder (iRBD), although no large patient group has been reported." | 4.02 | Treatment of isolated REM sleep behavior disorder using melatonin as a chronobiotic. ( Bes, F; Kunz, D; Stotz, S, 2021) |
| "To evaluate changes in the expression of clock genes and melatonin levels in patients with idiopathic REM sleep behavior disorder (RBD) as a potential early stage of synucleinopathies." | 3.88 | Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder. ( Bartoš, A; Bendová, Z; Bušková, J; Červená, K; Dudysová, D; Kopřivová, J; Miletínová, E; Skálová, K; Škrabalová, J; Šonka, K; Weissová, K, 2018) |
| "Melatonin and clonazepam were each reported to reduce RBD behaviors and injuries and appeared comparably effective in our naturalistic practice experience." | 3.79 | Treatment outcomes in REM sleep behavior disorder. ( Boeve, BF; Boswell, CL; Dueffert, LG; McCarter, SJ; Olson, EJ; Silber, MH; Slocumb, N; St Louis, EK; Tippmann-Peikert, M, 2013) |
| "Thirty PD patients with rapid eye movement sleep behavior disorder were randomized to 4 mg of prolonged-release melatonin (Circadin) or matched placebo, ingested orally once-daily before bedtime." | 2.94 | Melatonin for rapid eye movement sleep behavior disorder in Parkinson's disease: A randomised controlled trial. ( Coeytaux Jackson, A; Fang, BAM; Gilat, M; Grunstein, RR; Hall, JM; Hammond, D; Lewis, SJG; Marshall, NS; Mullins, AE; Wong, KKH; Yee, BJ, 2020) |
| " Switching to morning dosing or to an alternative drug may help." | 2.82 | [Sleep disorders in patients with a neurocognitive disorder]. ( Carrier, J; Dang-Vu, TT; Moderie, C, 2022) |
| "Patients with rapid eye movement sleep behavior disorder are frequently prone to sleep-related injuries and should be treated to prevent injury with either melatonin 3-12 mg or clonazepam 0." | 2.55 | REM Sleep Behavior Disorder in Parkinson's Disease and Other Synucleinopathies. ( Boeve, AR; Boeve, BF; St Louis, EK, 2017) |
| "Sleep disorders and neurodegenerative diseases are commonly encountered in primary care." | 2.53 | Importance of Rapid Eye Movement Sleep Behavior Disorder to the Primary Care Physician. ( Howell, MJ; McCarter, SJ, 2016) |
| "Melatonin also has a favorable safety and tolerability profile over clonazepam with limited potential for drug-drug interactions, an important consideration especially in elderly individuals with RBD receiving polypharmacy." | 2.52 | Melatonin therapy for REM sleep behavior disorder: a critical review of evidence. ( Boeve, BF; Leung, JG; McGrane, IR; St Louis, EK, 2015) |
| "Melatonin is a chronobiotic treatment which also alleviates rapid eye movement (REM) sleep behavior disorder (RBD)." | 1.43 | Loss of REM sleep features across nighttime in REM sleep behavior disorder. ( Arnaldi, D; Arnulf, I; Latimier, A; Leu-Semenescu, S; Vidailhet, M, 2016) |
| "To present a clinical case of idiopathic rapid eye movement sleep behavior disorder (RBD), differential diagnoses, selected treatments, and the pathology involved." | 1.36 | Making the diagnosis: idiopathic rapid eye movement sleep behavior disorder. ( Taub, LF, 2010) |
| "Clonazepam has been the first-line therapy for many years, with 2 large case series reporting efficacy with few side effects in the majority of patients." | 1.35 | Drug treatment of REM sleep behavior disorder: the use of drug therapies other than clonazepam. ( Anderson, KN; Shneerson, JM, 2009) |
| "Melatonin was successfully used as an alternative treatment." | 1.35 | REM sleep behaviour disorder treated with melatonin in a patient with Alzheimer's disease. ( Anderson, KN; Graham, AJ; Jamieson, S; Shneerson, JM, 2008) |
| "Clonazepam has been considered the treatment of choice for RBD." | 1.32 | Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients. ( Boeve, BF; Ferman, TJ; Silber, MH, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (15.38) | 29.6817 |
| 2010's | 23 (58.97) | 24.3611 |
| 2020's | 10 (25.64) | 2.80 |
| Authors | Studies |
|---|---|
| Moderie, C | 1 |
| Carrier, J | 1 |
| Dang-Vu, TT | 1 |
| Byun, JI | 2 |
| Shin, YY | 1 |
| Seong, YA | 1 |
| Yoon, SM | 1 |
| Hwang, KJ | 1 |
| Jung, YJ | 1 |
| Cha, KS | 1 |
| Jung, KY | 2 |
| Shin, WC | 1 |
| Howell, M | 2 |
| Avidan, AY | 2 |
| Foldvary-Schaefer, N | 2 |
| Malkani, RG | 2 |
| During, EH | 3 |
| Roland, JP | 2 |
| McCarter, SJ | 5 |
| Zak, RS | 3 |
| Carandang, G | 2 |
| Kazmi, U | 2 |
| Ramar, K | 3 |
| Dodet, P | 1 |
| Miglis, MG | 1 |
| Gilat, M | 2 |
| Coeytaux Jackson, A | 1 |
| Marshall, NS | 2 |
| Hammond, D | 1 |
| Mullins, AE | 1 |
| Hall, JM | 1 |
| Fang, BAM | 1 |
| Yee, BJ | 1 |
| Wong, KKH | 1 |
| Grunstein, RR | 1 |
| Lewis, SJG | 3 |
| Du, Y | 1 |
| Jiang, J | 1 |
| Ng, CH | 1 |
| Wu, L | 1 |
| Zhang, P | 1 |
| Xi, C | 1 |
| Lai, J | 1 |
| Xu, Y | 1 |
| Hu, S | 1 |
| Wang, Z | 1 |
| Matar, E | 2 |
| St Louis, EK | 4 |
| Testelmans, D | 1 |
| Buyse, B | 1 |
| Iranzo, A | 3 |
| Ramos, LA | 1 |
| Novo, S | 1 |
| Kunz, D | 5 |
| Stotz, S | 1 |
| Bes, F | 3 |
| Boeve, AR | 1 |
| Boeve, BF | 5 |
| Schaefer, C | 1 |
| Lewis, SJ | 1 |
| Dauvilliers, Y | 2 |
| Schenck, CH | 3 |
| Postuma, RB | 1 |
| Luppi, PH | 2 |
| Plazzi, G | 2 |
| Montplaisir, J | 1 |
| Boeve, B | 1 |
| Weissová, K | 1 |
| Škrabalová, J | 1 |
| Skálová, K | 1 |
| Červená, K | 1 |
| Bendová, Z | 1 |
| Miletínová, E | 1 |
| Kopřivová, J | 1 |
| Šonka, K | 2 |
| Dudysová, D | 1 |
| Bartoš, A | 1 |
| Bušková, J | 1 |
| Jun, JS | 1 |
| Kim, R | 1 |
| Kim, TJ | 1 |
| Lim, JA | 1 |
| Sunwoo, JS | 1 |
| Lee, ST | 1 |
| Jung, KH | 1 |
| Park, KI | 1 |
| Chu, K | 1 |
| Kim, M | 1 |
| Lee, SK | 1 |
| Montplaisir, JY | 1 |
| Frauscher, B | 1 |
| Hogl, B | 1 |
| Gagnon, JF | 1 |
| Postuma, R | 1 |
| Jennum, P | 1 |
| Partinen, M | 2 |
| Arnulf, I | 2 |
| Cochen de Cock, V | 1 |
| Heidbreder, A | 1 |
| Mayer, G | 1 |
| Sixel-Döring, F | 1 |
| Trenkwalder, C | 1 |
| Unger, M | 1 |
| Young, P | 1 |
| Wing, YK | 1 |
| Ferini-Strambi, L | 1 |
| Ferri, R | 1 |
| Zucconi, M | 1 |
| Inoue, Y | 1 |
| Santamaria, J | 1 |
| Bassetti, C | 1 |
| Möller, JC | 1 |
| Lai, YY | 1 |
| Pavlova, M | 1 |
| Saper, C | 1 |
| Schmidt, P | 1 |
| Siegel, JM | 1 |
| Singer, C | 1 |
| St Louis, E | 1 |
| Videnovic, A | 1 |
| Oertel, W | 1 |
| McGrane, IR | 1 |
| Leung, JG | 1 |
| Arnaldi, D | 1 |
| Latimier, A | 1 |
| Leu-Semenescu, S | 1 |
| Vidailhet, M | 1 |
| Escribá, J | 1 |
| Hoyo, B | 1 |
| Howell, MJ | 2 |
| Pillai, JA | 1 |
| Leverenz, JB | 1 |
| Billiard, M | 1 |
| Anderson, KN | 2 |
| Shneerson, JM | 2 |
| Aurora, RN | 1 |
| Maganti, RK | 1 |
| Auerbach, SH | 1 |
| Casey, KR | 1 |
| Chowdhuri, S | 1 |
| Karippot, A | 1 |
| Kristo, DA | 1 |
| Morgenthaler, TI | 1 |
| Mahlberg, R | 1 |
| Taub, LF | 1 |
| Rizzi, DA | 1 |
| Brooks, PL | 1 |
| Peever, JH | 1 |
| Arneson, PA | 1 |
| Ylikoski, A | 1 |
| Boswell, CL | 1 |
| Dueffert, LG | 1 |
| Slocumb, N | 1 |
| Silber, MH | 2 |
| Olson, EJ | 1 |
| Tippmann-Peikert, M | 1 |
| Ferman, TJ | 1 |
| Gugger, JJ | 1 |
| Wagner, ML | 1 |
| Jamieson, S | 1 |
| Graham, AJ | 1 |
| Takeuchi, N | 1 |
| Uchimura, N | 1 |
| Hashizume, Y | 1 |
| Mukai, M | 1 |
| Etoh, Y | 1 |
| Yamamoto, K | 1 |
| Kotorii, T | 1 |
| Ohshima, H | 1 |
| Ohshima, M | 1 |
| Maeda, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Melatonin and Rivotril Treatment for Idiopathic Rapid Eye Movement Sleep Disorder: Prospective Randomized Study.[NCT03255642] | 34 participants (Actual) | Interventional | 2017-11-09 | Completed | |||
| A Randomized Double-Blind, Double-Dummy, Crossover Study to Evaluate the Efficacy and Safety of Prolonged-Release Melatonin and Clonazepam in Patients With Rapid Eye Movement (REM) Sleep Behavior Disorder in Parkinson Disease[NCT02789592] | Phase 2 | 30 participants (Anticipated) | Interventional | 2016-07-31 | Not yet recruiting | ||
| DREAMER - IsolateD REM Sleep Without Atonia as a Risk Factor for REM Sleep Behavior disordER: Constitution of a Cohort for a Long-term Prospective Follow-up Study[NCT06140511] | 600 participants (Anticipated) | Observational | 2023-11-20 | Not yet recruiting | |||
| A Single Center, Open Label Prospective Observational Pilot Study to Evaluate the Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)[NCT05922995] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2023-09-30 | Not yet recruiting | ||
| Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism: a Prospective, Randomized, Double-blind and Placebo-controlled Trial[NCT02312908] | Phase 2 | 40 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic REM Sleep Behavior Disorder: a Pilot Study[NCT02836743] | Phase 4 | 30 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| Efficacy and Tolerability of Ramelteon in Patients With REM Behavior Disorder and Parkinsonism: A Placebo Controlled, Double Blind, Randomized, Prospective Pilot Study[NCT00745030] | 3 participants (Actual) | Interventional | 2008-06-30 | Terminated (stopped due to Low subject recruitment and enrollment.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for melatonin and REM Sleep Behavior Disorder
| Article | Year |
|---|---|
[Sleep disorders in patients with a neurocognitive disorder].
Topics: Alzheimer Disease; Chronobiology Disorders; Humans; Melatonin; REM Sleep Behavior Disorder; Restless | 2022 |
Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline.
Topics: Adult; Clonazepam; Humans; Melatonin; REM Sleep Behavior Disorder; Rivastigmine; Sleep; United State | 2023 |
Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline.
Topics: Adult; Clonazepam; Humans; Melatonin; REM Sleep Behavior Disorder; Rivastigmine; Sleep; United State | 2023 |
Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline.
Topics: Adult; Clonazepam; Humans; Melatonin; REM Sleep Behavior Disorder; Rivastigmine; Sleep; United State | 2023 |
Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline.
Topics: Adult; Clonazepam; Humans; Melatonin; REM Sleep Behavior Disorder; Rivastigmine; Sleep; United State | 2023 |
REM behavior disorder: When Parkinson's disease meets Morpheus.
Topics: Aged; Clonazepam; Humans; Melatonin; Parkinson Disease; REM Sleep Behavior Disorder; Synucleinopathi | 2023 |
Current Concepts and Controversies in the Management of REM Sleep Behavior Disorder.
Topics: Central Nervous System Depressants; Humans; Melatonin; REM Sleep Behavior Disorder; Treatment Outcom | 2021 |
A critical review of the pharmacological treatment of REM sleep behavior disorder in adults: time for more and larger randomized placebo-controlled trials.
Topics: Aged; Clonazepam; Double-Blind Method; Humans; Melatonin; Randomized Controlled Trials as Topic; REM | 2022 |
The Isolated Form of Rapid Eye Movement Sleep Behavior Disorder: The Upcoming Challenges.
Topics: Clonazepam; Dementia; Diagnostic Tests, Routine; Humans; Melatonin; Parkinson Disease; REM Sleep Beh | 2021 |
REM Sleep Behavior Disorder in Parkinson's Disease and Other Synucleinopathies.
Topics: Central Nervous System Depressants; Clonazepam; GABA Modulators; Humans; Lewy Body Disease; Melatoni | 2017 |
REM sleep behaviour disorder: not just a bad dream.
Topics: Clonazepam; Humans; Hypnotics and Sedatives; Melatonin; Polysomnography; REM Sleep Behavior Disorder | 2017 |
REM sleep behaviour disorder.
Topics: alpha-Synuclein; Antidepressive Agents; Central Nervous System Depressants; Clonazepam; Diagnosis, D | 2018 |
Melatonin therapy for REM sleep behavior disorder: a critical review of evidence.
Topics: Central Nervous System Depressants; Humans; Melatonin; REM Sleep Behavior Disorder; Treatment Outcom | 2015 |
Melatonin therapy for REM sleep behavior disorder: a critical review of evidence.
Topics: Central Nervous System Depressants; Humans; Melatonin; REM Sleep Behavior Disorder; Treatment Outcom | 2015 |
Melatonin therapy for REM sleep behavior disorder: a critical review of evidence.
Topics: Central Nervous System Depressants; Humans; Melatonin; REM Sleep Behavior Disorder; Treatment Outcom | 2015 |
Melatonin therapy for REM sleep behavior disorder: a critical review of evidence.
Topics: Central Nervous System Depressants; Humans; Melatonin; REM Sleep Behavior Disorder; Treatment Outcom | 2015 |
Importance of Rapid Eye Movement Sleep Behavior Disorder to the Primary Care Physician.
Topics: Central Nervous System Depressants; Clonazepam; Diagnosis, Differential; GABA Modulators; Humans; Me | 2016 |
Sleep and Neurodegeneration: A Critical Appraisal.
Topics: Alzheimer Disease; Dementia; Humans; Lewy Body Disease; Melatonin; Multiple System Atrophy; Neurodeg | 2017 |
REM sleep behavior disorder and narcolepsy.
Topics: Antidepressive Agents; Cataplexy; Clonazepam; Humans; Melatonin; Narcolepsy; Polysomnography; Preval | 2009 |
[REM sleep behavior disorder (RBD)].
Topics: Clonazepam; Diagnosis, Differential; GABA Modulators; Humans; Melatonin; Parkinson Disease; Polysomn | 2012 |
Rapid eye movement sleep behavior disorder.
Topics: Anticonvulsants; Antiparkinson Agents; Benzothiazoles; Clonazepam; Comorbidity; Dopamine Agonists; G | 2007 |
3 trials available for melatonin and REM Sleep Behavior Disorder
| Article | Year |
|---|---|
Comparative efficacy of prolonged-release melatonin versus clonazepam for isolated rapid eye movement sleep behavior disorder.
Topics: Clonazepam; Humans; Melatonin; Polysomnography; Prospective Studies; REM Sleep Behavior Disorder | 2023 |
Melatonin for rapid eye movement sleep behavior disorder in Parkinson's disease: A randomised controlled trial.
Topics: Aged; Clonazepam; Double-Blind Method; Eye Movements; Fatigue; Female; Humans; Male; Melatonin; Midd | 2020 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Topics: Adult; Aged; Central Nervous System Depressants; Double-Blind Method; Humans; Male; Melatonin; Middl | 2010 |
21 other studies available for melatonin and REM Sleep Behavior Disorder
| Article | Year |
|---|---|
Clinical trials in REM sleep behavior disorder: an urgent need for better evidence.
Topics: Aged; Anticonvulsants; Central Nervous System Depressants; Clinical Trials as Topic; Clonazepam; Fem | 2019 |
Vortioxetine improves rapid eye movement sleep behavior disorder: A case report.
Topics: Aged; Female; Humans; Melatonin; Polysomnography; REM Sleep Behavior Disorder; Treatment Outcome; Vo | 2020 |
Treatment of isolated REM sleep behavior disorder using melatonin as a chronobiotic.
Topics: Humans; Melatonin; REM Sleep Behavior Disorder; Reproducibility of Results; Sleep, REM | 2021 |
Melatonin Effects in REM Sleep Behavior Disorder Associated with Obstructive Sleep Apnea Syndrome: A Case Series.
Topics: Aged; Humans; Hypnotics and Sedatives; Male; Melatonin; Polysomnography; REM Sleep Behavior Disorder | 2017 |
Twenty Years After: Another Case Report of Melatonin Effects on REM Sleep Behavior Disorder, Using Serial Dopamine Transporter Imaging.
Topics: Aged; Brain; Central Nervous System Depressants; Dopamine Plasma Membrane Transport Proteins; Humans | 2017 |
Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder.
Topics: Aged; ARNTL Transcription Factors; Circadian Rhythm; CLOCK Proteins; Gene Expression; Humans; Male; | 2018 |
Prolonged-release melatonin in patients with idiopathic REM sleep behavior disorder.
Topics: Adult; Double-Blind Method; Female; Hong Kong; Humans; Male; Melatonin; Middle Aged; Pilot Projects; | 2019 |
Melatonin in rapid eye movement sleep behavior disorder: why does it work?
Topics: Animals; Central Nervous System Depressants; Chronobiology Phenomena; Humans; Melatonin; REM Sleep B | 2013 |
Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group.
Topics: Clinical Trials as Topic; Clonazepam; Consensus; GABA Modulators; Humans; Melatonin; Neuroprotective | 2013 |
Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group.
Topics: Clinical Trials as Topic; Clonazepam; Consensus; GABA Modulators; Humans; Melatonin; Neuroprotective | 2013 |
Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group.
Topics: Clinical Trials as Topic; Clonazepam; Consensus; GABA Modulators; Humans; Melatonin; Neuroprotective | 2013 |
Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group.
Topics: Clinical Trials as Topic; Clonazepam; Consensus; GABA Modulators; Humans; Melatonin; Neuroprotective | 2013 |
Loss of REM sleep features across nighttime in REM sleep behavior disorder.
Topics: Adult; Aged; Chronobiology Disorders; Electromyography; Female; Humans; Male; Melatonin; Middle Aged | 2016 |
Alternatives to Clonazepam in REM Behavior Disorder Treatment.
Topics: Clonazepam; Humans; Melatonin; Polysomnography; REM Sleep Behavior Disorder | 2016 |
Drug treatment of REM sleep behavior disorder: the use of drug therapies other than clonazepam.
Topics: Adjuvants, Anesthesia; Aged; Azabicyclo Compounds; Central Nervous System Depressants; Clonazepam; C | 2009 |
Best practice guide for the treatment of REM sleep behavior disorder (RBD).
Topics: Benzothiazoles; Central Nervous System Depressants; Clonazepam; Dopamine Agonists; GABA Modulators; | 2010 |
Making the diagnosis: idiopathic rapid eye movement sleep behavior disorder.
Topics: Aged; Anticonvulsants; Biomarkers; Central Nervous System Depressants; Clonazepam; Diagnosis, Differ | 2010 |
[Fighting with the Danish Medical Agency--core activity of the medical profession?].
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Depressants; Denmark; Humans; | 2010 |
Impaired GABA and glycine transmission triggers cardinal features of rapid eye movement sleep behavior disorder in mice.
Topics: Analysis of Variance; Animals; Brain; Central Nervous System Depressants; Clonazepam; Disease Models | 2011 |
A novel therapy for REM sleep behavior disorder (RBD).
Topics: Aged; Aged, 80 and over; Behavior Therapy; Clinical Alarms; Clonazepam; Drug Resistance; Female; Fol | 2011 |
Treatment outcomes in REM sleep behavior disorder.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Depressants; Clonazepam; Drug Therapy, Combin | 2013 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients.
Topics: Adult; Aged; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist | 2003 |
REM sleep behaviour disorder treated with melatonin in a patient with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Diagnosis, Differential; Hormones; Humans; Male; Melatonin; Polysomnography | 2008 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |
Melatonin therapy for REM sleep behavior disorder.
Topics: Electromyography; Female; Humans; Male; Melatonin; Middle Aged; Polysomnography; REM Sleep Behavior | 2001 |