Page last updated: 2024-10-19

melatonin and Protein Aggregation, Pathological

melatonin has been researched along with Protein Aggregation, Pathological in 3 studies

Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.

Research Excerpts

ExcerptRelevanceReference
"Melatonin is an endocrine hormone, secreted during darkness, derived from tryptophan, and produced mainly by the pineal gland."2.58Multi-Faceted Role of Melatonin in Neuroprotection and Amelioration of Tau Aggregates in Alzheimer's Disease. ( Balmik, AA; Chinnathambi, S, 2018)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balmik, AA1
Chinnathambi, S1
Zhang, LF1
Zhou, ZW1
Wang, ZH1
Du, YH1
He, ZX1
Cao, C1
Zhou, SF1
Cheng, S1
Zheng, W1
Gong, P1
Zhou, Q1
Xie, Q1
Yu, L1
Zhang, P1
Chen, L1
Li, J1
Chen, J1
Chen, H2

Reviews

1 review available for melatonin and Protein Aggregation, Pathological

ArticleYear
Multi-Faceted Role of Melatonin in Neuroprotection and Amelioration of Tau Aggregates in Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 62, Issue:4

    Topics: Alzheimer Disease; Animals; Humans; Melatonin; Neuroprotection; Protein Aggregates; Protein Aggregat

2018

Other Studies

2 other studies available for melatonin and Protein Aggregation, Pathological

ArticleYear
Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Amyloid beta-Peptides; Animals; Caffeine; Cell Survival; Coffee; Dose-Response Relationship, Drug; M

2015
(-)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer's therapy.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Cell Membrane Permeabil

2015