melatonin has been researched along with Prostatic Hyperplasia in 8 studies
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study showed that adding melatonin to the classic treatment of BPH patients with tamsulosin could significantly reduce the likelihood of nocturia by 2." | 9.51 | The effect of Melatonin on Improving the benign Prostatic Hyperplasia Urinary Symptoms, a Randomized Clinical Trial. ( Ayati, M; Fotovat, A; Momeni, SA; Nasseri, A; Nowroozi, MR; Samadzadeh, B; Sharifi, L; Yavari, S, 2022) |
| "This study showed that adding melatonin to the classic treatment of BPH patients with tamsulosin could significantly reduce the likelihood of nocturia by 2." | 5.51 | The effect of Melatonin on Improving the benign Prostatic Hyperplasia Urinary Symptoms, a Randomized Clinical Trial. ( Ayati, M; Fotovat, A; Momeni, SA; Nasseri, A; Nowroozi, MR; Samadzadeh, B; Sharifi, L; Yavari, S, 2022) |
| "The serum levels of the pineal hormone melatonin were determined by radioimmunoassay (RIA) in 4-h intervals throughout a 24-h period in elderly men with different types of prostate tumors: benign prostatic hyperplasia (BPH, n = 13), incidental carcinoma (PCi, n = 5), and nonmetastasizing carcinoma (PC, n = 9), as well as in young men (YM, n = 10)." | 3.67 | Evidence for modulation of melatonin secretion in men with benign and malignant tumors of the prostate: relationship with the pituitary hormones. ( Attanasio, A; Bartsch, C; Bartsch, H; Flüchter, SH; Gupta, D, 1985) |
| "Melatonin treatment is associated with a significant nocturia response rate, improvement in nocturia related bother and a good adverse effect profile." | 2.71 | Melatonin pharmacotherapy for nocturia in men with benign prostatic enlargement. ( Drake, MJ; Mills, IW; Noble, JG, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fotovat, A | 1 |
| Samadzadeh, B | 1 |
| Ayati, M | 1 |
| Nowroozi, MR | 1 |
| Momeni, SA | 1 |
| Yavari, S | 1 |
| Nasseri, A | 1 |
| Sharifi, L | 1 |
| Farahani, H | 1 |
| Alaee, M | 1 |
| Amri, J | 1 |
| Baghinia, MR | 1 |
| Rafiee, M | 1 |
| Kniaz'kin, IV | 1 |
| Drake, MJ | 1 |
| Mills, IW | 1 |
| Noble, JG | 1 |
| Laudon, M | 1 |
| Gilad, E | 2 |
| Matzkin, H | 2 |
| Braf, Z | 1 |
| Zisapel, N | 2 |
| Taverna, G | 1 |
| Trinchieri, A | 1 |
| Mandressi, A | 1 |
| Del Nero, A | 1 |
| Mangiarotti, B | 1 |
| Antonelli, D | 1 |
| Chisena, S | 1 |
| Pisani, E | 1 |
| Pick, E | 1 |
| Bartsch, C | 1 |
| Bartsch, H | 1 |
| Flüchter, SH | 1 |
| Attanasio, A | 1 |
| Gupta, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Open-label Study to Evaluate the Effects of a Prostate Health Formulation on Scores Attained From the International Prostate Symptom Score (I-PSS) Questionnaire Among Overall Healthy Male Participants Who Report Lower Urinary Tract Complaints[NCT02886832] | 30 participants (Anticipated) | Interventional | 2016-09-21 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for melatonin and Prostatic Hyperplasia
| Article | Year |
|---|---|
The effect of Melatonin on Improving the benign Prostatic Hyperplasia Urinary Symptoms, a Randomized Clinical Trial.
Topics: Double-Blind Method; Humans; Male; Melatonin; Middle Aged; Nocturia; Prostatic Hyperplasia; Sulfonam | 2022 |
Melatonin pharmacotherapy for nocturia in men with benign prostatic enlargement.
Topics: Aged; Aged, 80 and over; Double-Blind Method; Humans; Male; Melatonin; Middle Aged; Prostatic Hyperp | 2004 |
6 other studies available for melatonin and Prostatic Hyperplasia
| Article | Year |
|---|---|
Serum and Saliva Concentrations of Biochemical Parameters in Men with Prostate Cancer and Benign Prostate Hyperplasia.
Topics: beta 2-Microglobulin; Biomarkers; Case-Control Studies; Creatine Kinase, BB Form; Creatinine; Down-R | 2020 |
[Melatonin, aging and tumors of the prostate].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aging; Humans; Immunohistochemistry; Male; Melatonin | 2008 |
Putative melatonin receptors in benign human prostate tissue.
Topics: Aged; Animals; Autoradiography; Epithelium; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinet | 1996 |
Variation in nocturnal urinary excretion of melatonin in a group of patients older than 55 years suffering from urogenital tract disorders.
Topics: Aged; Aged, 80 and over; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Circadian Rhythm; Fema | 1997 |
Melatonin receptors in benign prostate epithelial cells: evidence for the involvement of cholera and pertussis toxins-sensitive G proteins in their signal transduction pathways.
Topics: Adenosine Diphosphate Ribose; Aged; Aged, 80 and over; Cells, Cultured; Cholera Toxin; Cyclic AMP; C | 1998 |
Evidence for modulation of melatonin secretion in men with benign and malignant tumors of the prostate: relationship with the pituitary hormones.
Topics: Aged; Circadian Rhythm; Follicle Stimulating Hormone; Growth Hormone; Humans; Luteinizing Hormone; M | 1985 |