melatonin and Presbyopia

melatonin has been researched along with Presbyopia in 1 studies

Presbyopia: The normal decreasing elasticity of the crystalline lens that leads to loss of accommodation.

Research

Studies (1)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Color Vision as Assessed by the Farnsworth Munsell 100 Hue Test

"The Farnsworth Munsell 100 hue test (X-Rite, USA) was used to evaluate colour vision. Each of the four trays consisted of 21 movable caps. Participants were asked to sort the randomly arranged caps following the hue order from the first to the last fixed caps. The total error score was calculated, as documented in the instruction manual, to quantify the accuracy of color discrimination.~There are no defined endpoints to the total error score range.~A lower score indicates improved color discrimination ability." (NCT02821403)
Timeframe: Every 1-month interval from the date of randomization, up to 3 months

Contrast Sensitivity as Assessed by Mars Contrast Sensitivity Chart

"Contrast sensitivity was measured using the Mars contrast sensitivity letter chart (Mars Perceptrix, Chappaqua, NY). One out of three charts differing in the letter combinations was selected randomly in order to avoid memorization of the charts. The chart was placed at 50 cm with each letter subtended 2° visual angle. We followed the recording procedures as specified by the manufacturer: participants were instructed to read the letters from high to low contrasts and the test ended when two consecutive errors were made. The contrast sensitivity was scored as the log contrast sensitivity of the last correct letter minus 0.04 log unit for every prior error. The test was administered under normal (room illumination, 400 lux) and glare conditions. A brightness acuity tester set at its medium light intensity level (100 foot lamberts) simulated the glaring condition.~A higher mean indicates improved contrast sensitivity." (NCT02821403)
Timeframe: Every 1-month interval from the date of randomization, up to 3 months

Self-assessment of Lens Performance Through Questionnaire

"After each monthly wearing period (visits 3-5), the participants' lens performance, night vision quality and sleep quality (total 13 questions) were assessed subjectively using a questionnaire (scoring from 1 [very unsatisfactory] to 5 [very satisfactory]).~At the end of the study, the participants were asked to choose their preferred lens type among the three pairs of lenses based on their subjective feeling of the best lens type (i.e., either clear lens, yellow tinted lens or blue-filtering coated lens).~To make it clear and simple, here we only present the data on the participants choice of their preferred lens type (i.e., simply choosing the best lens among clear lens, yellow tinted lens or blue-filtering coated lens)." (NCT02821403)
Timeframe: Every 1-month interval from the date of randomization, up to 3 months

Other Studies

1 other study available for melatonin and Presbyopia