melatonin has been researched along with Presbycusis in 4 studies
Presbycusis: Gradual bilateral hearing loss associated with aging that is due to progressive degeneration of cochlear structures and central auditory pathways. Hearing loss usually begins with the high frequencies then progresses to sounds of middle and low frequencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin treatment significantly improved hearing, decreased cytosolic mtDNA, suppressed the expression of inflammatory cytokines TNF-α, IL-6, IFN-β, Ifit3, and Cxcl10, down-regulated cGAS and STING expression, and attenuated IRF3 phosphorylation in the C57BL/6J mouse cochlea, inferior colliculus, and auditory cortex." | 5.91 | Melatonin Suppresses Cyclic GMP-AMP Synthase-Stimulator of Interferon Genes Signaling and Delays the Development of Hearing Loss in the C57BL/6J Presbycusis Mouse Model. ( Chen, H; Huang, J; Lin, X; Liu, J; Su, J; Tan, M; Xu, W; Zhu, X, 2023) |
| "Melatonin treatment significantly improved hearing, decreased cytosolic mtDNA, suppressed the expression of inflammatory cytokines TNF-α, IL-6, IFN-β, Ifit3, and Cxcl10, down-regulated cGAS and STING expression, and attenuated IRF3 phosphorylation in the C57BL/6J mouse cochlea, inferior colliculus, and auditory cortex." | 1.91 | Melatonin Suppresses Cyclic GMP-AMP Synthase-Stimulator of Interferon Genes Signaling and Delays the Development of Hearing Loss in the C57BL/6J Presbycusis Mouse Model. ( Chen, H; Huang, J; Lin, X; Liu, J; Su, J; Tan, M; Xu, W; Zhu, X, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, J | 1 |
| Chen, H | 1 |
| Lin, X | 1 |
| Zhu, X | 1 |
| Huang, J | 1 |
| Xu, W | 1 |
| Tan, M | 1 |
| Su, J | 1 |
| Serra, LSM | 1 |
| Araújo, JG | 1 |
| Vieira, ALS | 1 |
| Silva, EMD | 1 |
| Andrade, RR | 1 |
| Kückelhaus, SAS | 1 |
| Sampaio, ALL | 1 |
| Lasisi, AO | 1 |
| Fehintola, FA | 1 |
| Seidman, MD | 1 |
1 review available for melatonin and Presbycusis
| Article | Year |
|---|---|
Effects of dietary restriction and antioxidants on presbyacusis.
Topics: Animals; Antioxidants; Ascorbic Acid; Chromosome Deletion; Diet, Reducing; DNA, Mitochondrial; Energ | 2000 |
3 other studies available for melatonin and Presbycusis
| Article | Year |
|---|---|
Melatonin Suppresses Cyclic GMP-AMP Synthase-Stimulator of Interferon Genes Signaling and Delays the Development of Hearing Loss in the C57BL/6J Presbycusis Mouse Model.
Topics: Animals; Cytokines; Deafness; DNA, Mitochondrial; Interferons; Interleukin-6; Melatonin; Mice; Mice, | 2023 |
Role of melatonin in prevention of age-related hearing loss.
Topics: Administration, Oral; Animals; Antioxidants; Cadherins; Disease Models, Animal; Hair Cells, Auditory | 2020 |
Correlation between plasma levels of radical scavengers and hearing threshold among elderly subjects with age-related hearing loss.
Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Auditory Threshold; Cross-Sectional Studies; Female; | 2011 |