Page last updated: 2024-10-19

melatonin and Pregnancy

melatonin has been researched along with Pregnancy in 769 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"The present study was conducted to determine if increases in IGF-1 concentration, associated with treatment of ewes with melatonin, has beneficial effects on pregnancy rates when there is induction of estrus in anestrous ewes."9.34Greater concentrations of IGF-1 are associated with increasing pregnancy rate in melatonin implanted anestrous Barki ewes. ( El-Mokadem, MY; Nour El-Din, ANM; Ramadan, TA; Rashad, AM; Samak, MA; Sharaby, MA; Taha, TA, 2020)
"melatonin ameliorates the activity of myo-inositol and folic acid by improving oocyte quality and pregnancy outcome in women with low oocyte quality history."9.14Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial. ( Benedetto, V; Raffone, E; Rizzo, P, 2010)
"The purpose of this review was to search for articles on human studies investigating the relationship between melatonin and high-risk pregnancy."9.12Relationship between melatonin and high-risk pregnancy: A review of investigations published between the years 2010 and 2020. ( Gheno, BR; Laste, G; Rychcik, PM; Silva, AAD, 2021)
"The aim of this review is to clarify the interrelationship between melatonin and autism spectrum disorder (ASD) during fetal development."8.98The Relationship between Autism Spectrum Disorder and Melatonin during Fetal Development. ( Choi, J; Hong, Y; Jin, Y; Won, J, 2018)
"We planned to include randomised controlled trials and quasi-randomised controlled trials comparing melatonin given to women in pregnancy (regardless of the route, timing, dose and duration of administration) for fetal neuroprotection with placebo, no treatment, or with an alternative agent aimed at providing fetal neuroprotection."8.93Melatonin for women in pregnancy for neuroprotection of the fetus. ( Shepherd, E; Wallace, EM; Wilkinson, D, 2016)
"The purpose of this systematic review is to access the current state of knowledge concerning the role for melatonin in human pregnancy."8.84Melatonin and pregnancy in the human. ( Flores, LJ; Manchester, LC; Nakamura, Y; Reiter, RJ; Sugino, N; Tamura, H; Tan, DX; Terron, MP, 2008)
"To investigate, in the liver of adult offspring, the possible effects of melatonin supplementation in the obese mother during pregnancy and lactation."8.31Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress. ( Aguila, MB; Ajackson, M; Mandarim-de-Lacerda, CA; Marcondes-de-Castro, IA; Nagagata, BA, 2023)
" This study examined the effects of maternal obesity on human colostrum lymphocytes and the intracellular mechanisms of lymphocyte modulation in the presence of leptin, adiponectin, and melatonin via cell proliferation; the release of intracellular calcium; and apoptosis induction."8.31Leptin, Adiponectin, and Melatonin Modulate Colostrum Lymphocytes in Mothers with Obesity. ( Abreu, LC; Bezerra, IMP; Daboin, BEG; de Quental, OB; França, EL; Honório-França, AC; Morais, TC; Pereira, GDAV; Pessoa, RS, 2023)
"This study was designed to investigate the roles of melatonin administration during different sensitive windows of the first half of pregnancy in the function and gene expression of the ovary and placenta, hormone profile, and pregnancy outcomes in rabbits."8.31Melatonin administration during the first half of pregnancy improves the reproductive performance of rabbits: Emphasis on ovarian and placental functions. ( El-Bassiony, MF; El-Hawy, AS; Ghanem, N; Hashem, NM; Radwan, MA; Saber, A, 2023)
" Methadone is recommended for the treatment of opioid use disorders during pregnancy, increasing the number of children prenatally exposed to long-acting opioids."8.31Methadone administered to rat dams during pregnancy and lactation affects the circadian rhythms of their pups. ( Bendová, Z; Novotný, J; Pačesová, D; Spišská, V, 2023)
"In the present study, we set out to determine whether melatonin combined with a high-fat diet during pregnancy and lactation can prevent liver disorders in offspring."8.31Melatonin associated with a high-fat diet during pregnancy and lactation prevents liver changes in the offspring. ( Alpiovezza, PKBM; de Albuquerque, YML; de Melo, IMF; Francisco Soares, A; Lapa Neto, CJC; Teixeira, ÁAC; Wanderley-Teixeira, V, 2023)
"Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and molecular levels, this study investigated whether maternal treatment with melatonin protects against programmed cardiovascular dysfunction in the offspring using an established rodent model of hypoxic pregnancy."8.12Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy. ( Blanco, CE; Camm, EJ; Galli, GLJ; Giussani, DA; Hansell, JA; Herrera, EA; Lock, MC; Patey, OV; Richter, HG; Trafford, AW; Villamor, E, 2022)
" Supplementing dietary melatonin during a compromised pregnancy increased uteroplacental blood flow and prevented IUGR in a seasonal-dependent manner."8.12Seasonal and temporal variation in the placenta during melatonin supplementation in a bovine compromised pregnancy model. ( Burnett, DD; Cochran, T; Contreras-Correa, ZE; Lemley, CO; Metcalfe, A, 2022)
"Acute toxoplasmosis during pregnancy increases the risk of abortion through reduction of maternal serum melatonin level and dysregulation of pro-inflammatory/inflammatory cytokines axis."8.02Are alterations in melatonin and inflammatory cytokine serum levels linked with recurrent abortion in pregnant women with acute toxoplasmosis: The interacted nexus. ( Al-Kuraishi, AH; Al-Kuraishy, HM; Hasan, HH; Khalil, HI, 2021)
"Melatonin and interleukin -10 were significantly lower in subjects with intrahepatic cholestasis of pregnancy (p=0."8.02The Role of Melatonin, IL-8 and IL-10 in Intrahepatic Cholestasis of Pregnancy. ( Çalışkan, C; Çelik, S; Guve, H, 2021)
" Melatonin is involved in the outcome of normal pregnancy."8.02Impact of Melatonin on Full-Term Fetal Brain Development and Transforming Growth Factor-β Level in a Rat Model of Preeclampsia. ( Aref, M; El-Malkey, NF; Emam, H; Khalil, SS, 2021)
"Although there is abundant evidence to demonstrate that maternal smoking during pregnancy will harm the health of future generations, the impact of nicotine use by pregnant woman upon the oogenesis and folliculogenesis of female offspring has not been as widely scrutinized."7.96Melatonin ameliorates murine fetal oocyte meiotic dysfunction in F1 and F2 offspring caused by nicotine exposure during pregnancy. ( Cheng, SF; De Felici, M; Klinger, FG; Li, L; Liu, J; Liu, WX; Shen, W; Sun, XF; Tan, SJ; Wang, YF, 2020)
"Melatonin has been shown to improve in vitro fertilization and offspring survival after bacterial infection, but its role in regulating maternal-fetal communication during early pregnancy has not been investigated."7.96Melatonin improves uterine-conceptus interaction via regulation of SIRT1 during early pregnancy. ( Bae, H; Bazer, FW; Lee, JY; Lim, W; Park, S; Song, G; Yang, C, 2020)
"Inflammation is associated with injury to immature lungs, and melatonin administration to preterm newborns with acute respiratory distress improves pulmonary outcomes."7.96Melatonin for prevention of fetal lung injury associated with intrauterine inflammation and for improvement of lung maturation. ( Burd, I; Chudnovets, A; Kang, Y; Lee, JY; Lei, J; Na, Q; Shin, HE; Shin, NE; Song, H, 2020)
"Maternally administered melatonin modulated immune responses to maternal inflammation and decreased preterm birth and perinatal brain injury."7.91Administration of melatonin for prevention of preterm birth and fetal brain injury associated with premature birth in a mouse model. ( Burd, I; Dash, O; Hwang, JY; Lee, JY; Lei, J; McLane, MW; Park, M; Shin, NE; Song, H, 2019)
"To test whether melatonin plays an important role in the process of early pregnancy, melatonin was given in drinking water to pregnant mice at different gestation stages."7.85Effects of Melatonin on Early Pregnancy in Mouse: Involving the Regulation of StAR, Cyp11a1, and Ihh Expression. ( Guan, S; Jing, W; Liu, G; Liu, Z; Lv, D; Ma, T; Song, Y; Tian, X; Xiao, X; Xie, L, 2017)
"Hypertension can originate from early-life insults, whereas maternal melatonin therapy can be protective in a variety of models of programmed hypertension."7.85Maternal melatonin or agomelatine therapy prevents programmed hypertension in male offspring of mother exposed to continuous light. ( Chan, JYH; Hsu, CN; Lee, CT; Lin, YJ; Tain, YL, 2017)
"Background The aim of the present study is to evaluate the utility of extraction versus non-extraction-based commercial melatonin ELISA kits for determining the melatonin concentration in amniotic fluid obtained in early and late pregnancy."7.85Evaluation of two commercially available ELISA kits for the determination of melatonin concentrations in amniotic fluid throughout pregnancy. ( Altuntas, Ö; Bagci, S; Bartmann, P; Berg, C; Katzer, D; Müller, A; Reutter, H; Willruth, A; Zur, B, 2017)
"Melatonin was effective in the treatment of experimental endometriosis induced in SCID mice."7.83The effects of melatonin on endometriotic lesions induced by implanting human endometriotic cells in the first SCID-mouse endometriosis-model developed in Turkey. ( Akkaya, H; Attar, R; Ozkan, F; Yesildaglar, N; Yildirim, G; Yildirim, OK; Yilmaz, B, 2016)
"Experimental studies in animal models supporting protective effects on the fetus of melatonin in adverse pregnancy have prompted clinical trials in human pregnancy complicated by fetal growth restriction."7.81Melatonin modulates the fetal cardiovascular defense response to acute hypoxia. ( Allison, BJ; Botting, KJ; Giussani, DA; Herrera, EA; Niu, Y; Serón-Ferré, M; Thakor, AS, 2015)
"In order to show that a combination of melatonin and prostaglandins may be useful to save lives, we use newborn rat as a model of necrotizing enterocolitis to test the hypothesis of using the combination therapy might have more potential effect on mucosal cytoprotection and healing."7.79Evaluation of melatonin and prostaglandin E1 combination on necrotizing enterocolitis model in neonatal rats. ( Canpolat, FE; Cekmez, F; Cetinkaya, M; Kafa, IM; Sarıcı, SÜ; Tayman, C; Tunc, T; Uysal, S, 2013)
"Although melatonin supplementation is known to influence numerous physiological functions, little is however known of its effects on pregnancy outcome."7.79Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats. ( Gupalo, S; Omar, E; Saleh, HI; Singh, HJ, 2013)
"The purpose of this study was to investigate whether prophylactic administration of melatonin to the mother throughout pregnancy could protect against ischemia/reperfusion (I/R)-induced oxidative brain damage in neonatal rats."7.78Prophylactic administration of melatonin to the mother throughout pregnancy can protect against oxidative cerebral damage in neonatal rats. ( Fukaya, T; Hamada, F; Hayashi, Y; Imamura, R; Nagai, R; Shinohara, K; Wakatsuki, A; Watanabe, K, 2012)
"Female Swiss Albino rats were divided into five groups: intact control group; saline control group; epilepsy group; epilepsy plus Px group; and melatonin-treated epilepsy plus Px group."7.74Efficacy of melatonin on offspring liver maturation in pinealectomized pregnant rats subjected to experimental epilepsy. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yavaşoğlu, A; Yurtseven, M, 2007)
" The aim of this study was to investigate the protective effects in rat maternal and fetal livers as also the placenta of melatonin or silymarin against the oxidative stress and apoptosis induced by maternal obstructive cholestasis during the last third of pregnancy (OCP)."7.74Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio. ( Castaño, B; Gonzalez-Buitrago, JM; Marin, JJ; Perez, MJ, 2007)
"In this study, rats were randomly divided into four groups (ten animals each): intact control group, epilepsy control group, surgical pinealectomy + epilepsy group, and group with melatonin treatment following pinealectomy procedure."7.73Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yurtseven, ME, 2006)
"The aim of the present study was to test the hypothesis that the natural antioxidant melatonin (MEL) and the synthetic antioxidant stobadine (STO) could reduce the incidence of maternal and embryofoetal toxicity in rats due to intrauterine hypoxia."7.72Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration. ( Brucknerová, I; Dubovický, M; Juránek, I; Mach, M; Navarová, J; Soltés, L; Ujházy, E; Zeman, M, 2004)
"Sexual development of female and male rat offspring of control, pinealectomized (PIN-X) or melatonin (MEL 250 micrograms/100 g body wt)-treated mother rats during pregnancy was studied."7.69Effect of pinealectomy and melatonin treatment during pregnancy on the sexual development of the female and male rat offspring. ( Arce Fraguas, A; Colmenero Urquijo, MD; Díaz López, B; Díaz Rodriguez, ME; Esquifino Parras, A; Marín Fernández, B, 1995)
"An experiment was designed to study if, in the same animals, characteristics of the plasma melatonin rhythm vary during pregnancy in ewes."7.69The characteristics of the melatonin secretory rhythm are not modified by the stage of pregnancy in ewes. ( Chemineau, P; Malpaux, B; Zarazaga, LA, 1997)
"The influence of pineal gland function and of melatonin during pregnancy upon sexual maturation of female offspring in rats was examined."7.68Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat. ( Colmenero, MD; Díaz, B; Esquifino, A; González, ML; Marín, B; Miguel, JL, 1991)
"Plasma concentrations of immunoreactive melatonin, estradiol, progesterone, follicle stimulating hormone (FSH), and beta-human chorionic gonadotropin (beta hCG) were studied between 1000 and 1230 h in 105 Chinese females during six periods of normal pregnancy and 1-5 min after normal delivery."7.67Plasma levels of immunoreactive melatonin, estradiol, progesterone, follicle stimulating hormone, and beta-human chorionic gonadotropin during pregnancy and shortly after parturition in humans. ( Ng, KW; Pang, SF; Tang, GW; Tang, PL; Yam, AW, 1987)
"Melatonin is a natural neuroprotective hormone, which makes it promising for the treatment of neurodegeneration after asphyxia."7.01Melatonin: A Potential Candidate for the Treatment of Experimental and Clinical Perinatal Asphyxia. ( Furmaga-Jabłońska, W; Januszewski, S; Pluta, R; Tarkowska, A, 2023)
"Gestational diabetes mellitus is an important public health problem and has been associated with the development of pregnancy-specific urinary incontinence."7.01Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with gestational diabetes mellitus. ( Barbosa, AMP; França, DCH; França, EL; Honorio-França, AC; Rudge, MVC; Sobrevia, L, 2023)
"Melatonin is a neuroendocrine hormone which regulates circadian rhythm and is also an antioxidant."6.94Maternal Serum Melatonin Increases During Pregnancy and Falls Immediately After Delivery Implicating the Placenta as a Major Source of Melatonin. ( Ejaz, H; Figaro, JK; Galley, HF; Thottakam, BMV; Woolner, AMF, 2020)
"Melatonin therapy was safe for mothers and their fetuses."6.87Melatonin improves endothelial function in vitro and prolongs pregnancy in women with early-onset preeclampsia. ( Alers, NO; Gurusinghe, S; Hobson, SR; Kingdom, JC; Lim, R; Miller, SL; Wallace, EM, 2018)
"Placental insufficiency affects about 10% of pregnancies and can lead to pre-eclampsia, fetal growth restriction, and preterm birth."6.82The role of melatonin in pregnancies complicated by placental insufficiency: A systematic review. ( Bussolaro, S; Fantasia, I; Rolnik, DL; Stampalija, T, 2022)
"Fetal intrauterine growth restriction (IUGR) is a serious pregnancy complication associated with increased rates of perinatal morbidity and mortality, and ultimately with long-term neurodevelopmental impairments."6.79Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction. ( Alers, NO; Castillo-Melendez, M; Drummond, GR; Jenkin, G; Loose, JM; Miller, SL; Sabaretnam, T; Supramaniam, VG; VanZyl, N; Walker, DW; Wallace, EM; Yawno, T, 2014)
"Intrauterine inflammation is shown to be associated with preterm birth, fetal inflammatory response syndrome, and other pregnancy-related comorbidities such as central nervous system diseases including cerebral palsy and periventricular leukomalacia, pulmonary diseases such as bronchopulmonary dysplasia and respiratory distress syndrome, and necrotizing enterocolitis, to name a few."6.72Melatonin for the prevention of fetal injury associated with intrauterine inflammation. ( Kim, JM; Lee, JY; Lee, SY, 2021)
"Melatonin is an important neuroprotective factor and its receptors are expressed in the fetal brain."6.53Melatonin in Pregnancy: Effects on Brain Development and CNS Programming Disorders. ( Assunção Salustiano, EM; Sagrillo-Fagundes, L; Soliman, A; Vaillancourt, C; Yen, PW, 2016)
"Melatonin is an endogenously produced indoleamine and secreted by the pineal gland."6.50Transcriptional regulation of programmed hypertension by melatonin: an epigenetic perspective. ( Chan, JY; Huang, LT; Tain, YL, 2014)
"Treatment with melatonin might result in a wide range of health benefits, including improved quality of life and reduced healthcare costs."6.48Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period. ( Aversa, S; Barberi, I; Gitto, E; Pellegrino, S; Reiter, RJ, 2012)
"In women who developed preeclampsia during pregnancy, circadian oscillations of placental macrophages were lost and could not be rescued by coculture with trophoblasts from healthy women."5.91Disruption of the Expression of the Placental Clock and Melatonin Genes in Preeclampsia. ( Bretelle, F; Coiffard, B; Desbriere, R; Diallo, AB; Donato, X; Katsogiannou, M; Mege, JL; Mezouar, S, 2023)
"The study involved 32 women with preeclampsia and 33 healthy pregnant women as a control group."5.91Changes in concentrations of melatonin, PlGF, and cytokines in women with preeclampsia. ( Mykhailovych Barbe, A; Mykhailovych Yuzko, O; Mykolaiovych Berbets, A; Radu, MR; Savka, RF, 2023)
"Treatment with melatonin restored the HI-induced effects on miR-126/miR-146a expressions, both in the cerebral cortex and in serum."5.91MiR-126 and miR-146a as Melatonin-Responsive Biomarkers for Neonatal Brain Ischemia. ( Albertini, MC; Balduini, W; Buonocore, G; Carloni, S; Dell'Orto, V; Perrone, S; Vanzolini, T; Weiss, MD, 2023)
"Melatonin may inhibit HtrA1 transcription through the miR-520c-3p/SETD7 axis to promote trophoblast invasion and migration and reduce trophoblast pyroptosis in PE."5.72Melatonin regulates trophoblast pyroptosis, invasion and migration in preeclampsia by inhibiting HtrA1 transcription through the microRNA-520c-3p/SETD7 axis. ( Chang, J; Chen, B; Feng, L; Liu, Z; Zhao, X, 2022)
"Melatonin is an endogenous hormone and can restore gut microbial dysbiosis under various disease conditions."5.72Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism. ( Cui, Y; Li, XG; Liu, W; Liu, X; Qiu, B; Wang, X; Xiang, G; Yu, M; Zhang, D; Zhang, Y, 2022)
"Melatonin (5 mg/kg) was injected i."5.62Partial protective effects of melatonin on developing brain in a rat model of chorioamnionitis. ( Bodard, S; Chalon, S; Favrais, G; Gressens, P; Gulhan, Z; Saliba, E; Savary, L, 2021)
"Melatonin is a hormone and antioxidant produced by the pineal gland and placenta."5.62Melatonin, a Potential Therapeutic Agent for Preeclampsia, Reduces the Extrusion of Toxic Extracellular Vesicles from Preeclamptic Placentae. ( Chamley, L; Chen, Q; Groom, K; Tang, Y, 2021)
"Melatonin treatment also reduced sFlt-1, increased PlGF, and decreased the sFlt-1/PlGF ratio."5.56Melatonin attenuates hypertension and oxidative stress in a rat model of L-NAME-induced gestational hypertension. ( Jiang, Z; Zuo, J, 2020)
" Because children with CP from preterm birth also exhibit a sustained immune system hyper-reactivity, we hypothesized that neuro-immunomodulation with a regimen of repurposed endogenous neurorestorative medications, erythropoietin (EPO) and melatonin (MLT), could improve this trajectory."5.51Infantile Cocktail of Erythropoietin and Melatonin Restores Gait in Adult Rats with Preterm Brain Injury. ( Burkhardt, C; Burton, VJ; Fouda, MA; Gerner, G; Hamimi, S; Jantzie, LL; Kitase, Y; Muthukumar, S; Northington, FJ; Robinson, S; Scafidi, J; Vasan, V; Ye, X, 2022)
"Treatment with melatonin significantly reduced cypermethrin-induced genetic damage in dams and pups; however, melatonin was not effective against the genetic damage caused by methomyl."5.51Genotoxic and mutagenic evaluation of the protective effect of exogenous melatonin in adult rats and their offspring exposed to the insecticides methomyl and cypermethrin during pregnancy. ( Chagas, CA; Coelho Teixeira, ÁA; da Silva, MA; de Sousa Coelho, IDD; do Nascimento Marinho, KS; Dos Santos, KRP; Gomes Melo, ME; Lapa Neto, CJC; Teixeira, VW, 2019)
"Melatonin has been shown to reduce oxidative stress and mitigate hypercoagulability."5.51Melatonin for prevention of placental malperfusion and fetal compromise associated with intrauterine inflammation-induced oxidative stress in a mouse model. ( Burd, I; Dong, J; Jia, B; Jones-Beatty, K; Lee, JY; Lei, J; Li, S; McLane, MW; Na, Q; Ozen, M; Shin, NE, 2019)
"Low melatonin levels are a frequent finding in ASD patients."5.48Low maternal melatonin level increases autism spectrum disorder risk in children. ( Braam, W; Curfs, L; Ehrhart, F; Maas, APHM; Smits, MG, 2018)
" We examined whether maternal melatonin therapy can prevent maternal high-fructose combined with post-weaning high-salt diet-induced programmed hypertension in adult offspring."5.48Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring. ( Chan, JYH; Lee, WC; Leu, S; Tain, YL; Wu, KLH, 2018)
"Melatonin did not increase HO-1 expression in any of the tissues examined."5.48Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia. ( Beard, S; Binder, NK; Hannan, NJ; Kaitu'u-Lino, TJ; Nguyen, TV; Tong, S, 2018)
"Melatonin is a powerful antioxidant that can act as a protective agent against DNA damage caused by genotoxic agents, such as ethanol."5.48Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy. ( Chagas, CA; Lapa Neto, CJC; Santos, KRPD; Silva, MAD; Sousa Coelho, IDD; Souza, TGDS; Teixeira, ÁAC; Wanderley Teixeira, V, 2018)
"Melatonin was administered in drinking water (0."5.43Postnatal dexamethasone-induced programmed hypertension is related to the regulation of melatonin and its receptors. ( Chang, HY; Tain, YL, 2016)
"Serum was collected from women with preeclampsia (n=113) and gestation-matched healthy pregnant women, and the levels of melatonin were measured."5.43The reduction in circulating levels of melatonin may be associated with the development of preeclampsia. ( Chen, Q; Gao, Y; Lee, AC; Tong, M; Wan, J; Zeng, K; Zhao, M, 2016)
"Melatonin (5 mg/kg) was administered i."5.43Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway. ( Albertini, MC; Balduini, W; Buonocore, G; Carloni, S; Chalon, S; Favrais, G; Gressens, P; Longini, M; Saliba, E, 2016)
" Melatonin supplementation during pregnancy emerges as a promising intervention, although further investigation is required to fully understand the precise mechanisms involved and to develop effective strategies for promoting health and preventing NCDs in individuals affected by gestational chronodisruption."5.41From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin. ( Corvalan, F; Ehrenfeld, P; Halabi, D; Maldonado, R; Méndez, N; Seron-Ferre, M; Torres-Farfan, C; Vergara, K, 2023)
"Melatonin was reported to prevent hypertension development."5.40Melatonin prevents maternal fructose intake-induced programmed hypertension in the offspring: roles of nitric oxide and arachidonic acid metabolites. ( Chan, JY; Lee, WC; Leu, S; Tain, YL; Wu, KL, 2014)
"Melatonin plays pivotal role in biological circadian rhythms."5.40Melatonin secretion is impaired in women with preeclampsia and an abnormal circadian blood pressure rhythm. ( Arampatzis, S; Bouchlariotou, S; Eleftheriadis, T; Giannopoulou, M; Liakopoulos, V; Mertens, PR; Messinis, IE; Stefanidis, I; Zintzaras, E, 2014)
"Placentas were classified into gestational hypertension (GH), chronic hypertension (CH), pre-eclampsia (PE) and pre-eclampsia superimposed on chronic hypertension, and morphologically examined by hematoxylin-eosin and periodic acid Schiff methods."5.39Increase of placental sensitivity to melatonin and the alteration to its local synthesis in hypertensive syndromes in pregnancy. ( Corrêa, RR; Guimarães, CS; Machado, JR; Reis, MA; Rocha, LP; Yamamoto, Dde R; Yamamoto, Lde R, 2013)
"Melatonin also acts as a potent endogenous antioxidant by scavenging free radicals and upregulating antioxidant pathways."5.35Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy. ( Giussani, DA; Hansell, JA; Raut, S; Richter, HG, 2009)
"Treatment with melatonin during pregnancy improved learning deficits and prevented the reduction of glial and neuronal markers induced by hyperhomocysteinemia."5.35Melatonin prevents gestational hyperhomocysteinemia-associated alterations in neurobehavioral developments in rats. ( Baydas, G; Koz, ST; Nedzvetsky, VS; Tuzcu, M, 2008)
"The present study was conducted to determine if increases in IGF-1 concentration, associated with treatment of ewes with melatonin, has beneficial effects on pregnancy rates when there is induction of estrus in anestrous ewes."5.34Greater concentrations of IGF-1 are associated with increasing pregnancy rate in melatonin implanted anestrous Barki ewes. ( El-Mokadem, MY; Nour El-Din, ANM; Ramadan, TA; Rashad, AM; Samak, MA; Sharaby, MA; Taha, TA, 2020)
"Melatonin is a powerful endogenous antioxidant."5.33Melatonin protects against lipopolysaccharide-induced intra-uterine fetal death and growth retardation in mice. ( Chen, YH; Sun, MF; Wang, H; Wang, JP; Wei, LZ; Wei, W; Xu, DX, 2006)
" Melatonin is a hormone with antioxidant and anti-inflammatory effects that make it a promising molecule for the treatment of perinatal asphyxia."5.22Melatonin Administration from 2000 to 2020 to Human Newborns with Hypoxic-Ischemic Encephalopathy. ( Cannavò, L; D'angelo, G; Gitto, E; Reiter, RJ, 2022)
"Previously we reported increased umbilical artery blood flow in ewes supplemented with melatonin from mid- to late-pregnancy, while maternal nutrient restriction decreased uterine artery blood flow."5.20Effect of melatonin or maternal nutrient restriction on vascularity and cell proliferation in the ovine placenta. ( Borowicz, PP; Camacho, LE; Dorsam, S; Eifert, AW; Haring, J; Lemley, CO; Redmer, DA; Romero, S; Vonnahme, KA; Wilson, ME, 2015)
"A study was conducted to test the hypotheses that exogenous melatonin treatment of 11-13 month-old red deer hinds: (1) advances the timing of first ovulation, (2) increases the proportion of individuals attaining puberty at ∼16 months of age, and (3) reduces the live-weight threshold for attainment of first pregnancy."5.15Effect of melatonin implants on the incidence and timing of puberty in female red deer (Cervus elaphus). ( Archer, JA; Asher, GW; Littlejohn, RP; Scott, IC; Ward, JF, 2011)
"In the present study, we aim to evaluate the pregnancy outcomes after the administration of myo-inositol combined with melatonin in women who failed to conceive in previous in vitro fertilization (IVF) cycles due to poor oocyte quality."5.15Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study. ( Buffo, S; Raffone, E; Rizzo, P; Unfer, V, 2011)
" The mechanisms of the participation of melatonin in the regulation of metabolic processes and the key role of maternal melatonin in the formation of the circadian system of regulation in the fetus and in the protection of the genetic program of its morphofunctional development during pregnancy complications are presented."5.12Maternal Melatonin Deficiency Leads to Endocrine Pathologies in Children in Early Ontogenesis. ( Evsyukova, II; Ivanov, DO; Kvetnoy, IM; Mironova, ES; Nasyrov, RA; Polyakova, VO, 2021)
" Melatonin, a biologically active substance, acts as a pleiotropic hormone essential for pregnancy and fetal development."5.01Perinatal Use of Melatonin for Offspring Health: Focus on Cardiovascular and Neurological Diseases. ( Hsu, CN; Huang, LT; Tain, YL, 2019)
" The emerging evidence has proven that circadian rhythm deregulation followed by low circulating melatonin is associated with low implantation rates and difficulties to maintain pregnancy."5.01Melatonin Promotes Uterine and Placental Health: Potential Molecular Mechanisms. ( Chuffa, LGA; Cucielo, MS; Lupi, LA; Reiter, RJ; Seiva, FRF; Silveira, HS, 2019)
"The aim of this review is to clarify the interrelationship between melatonin and autism spectrum disorder (ASD) during fetal development."4.98The Relationship between Autism Spectrum Disorder and Melatonin during Fetal Development. ( Choi, J; Hong, Y; Jin, Y; Won, J, 2018)
"These results point to a significant role for circulating melatonin in the timing and degree of uterine contractions in late-term pregnancy."4.90Clinical significance of melatonin receptors in the human myometrium. ( Beesley, S; Olcese, J, 2014)
" In particular, two natural molecules have been shown to exert beneficial effects on fertility, pregnancy wellness and embryo development: myo-inositol and melatonin, whose requirements increase during pregnancy."4.87Contribution of myo-inositol and melatonin to human reproduction. ( Carlomagno, G; Chiu, TT; Nordio, M; Unfer, V, 2011)
" Included in this group of conditions is asphyxia, respiratory distress syndrome and sepsis and the review also summarizes the literature related to clinical trials of antioxidant therapies and of melatonin, a highly effective antioxidant and free radical scavenger."4.85Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin. ( Barberi, I; Gitto, E; Gitto, P; Pellegrino, S; Reiter, RJ, 2009)
"The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate."4.84Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007)
"The purpose of this systematic review is to access the current state of knowledge concerning the role for melatonin in human pregnancy."4.84Melatonin and pregnancy in the human. ( Flores, LJ; Manchester, LC; Nakamura, Y; Reiter, RJ; Sugino, N; Tamura, H; Tan, DX; Terron, MP, 2008)
" The following communication is concerned with the association among MS, pregnancy, the postpartum period, and melatonin secretion and illustrates, based on a clinical case report, the influence of the pineal gland on the clinical course of MS."4.78The pineal gland and the clinical course of multiple sclerosis. ( Sandyk, R, 1992)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"To investigate, in the liver of adult offspring, the possible effects of melatonin supplementation in the obese mother during pregnancy and lactation."4.31Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress. ( Aguila, MB; Ajackson, M; Mandarim-de-Lacerda, CA; Marcondes-de-Castro, IA; Nagagata, BA, 2023)
" This study examined the effects of maternal obesity on human colostrum lymphocytes and the intracellular mechanisms of lymphocyte modulation in the presence of leptin, adiponectin, and melatonin via cell proliferation; the release of intracellular calcium; and apoptosis induction."4.31Leptin, Adiponectin, and Melatonin Modulate Colostrum Lymphocytes in Mothers with Obesity. ( Abreu, LC; Bezerra, IMP; Daboin, BEG; de Quental, OB; França, EL; Honório-França, AC; Morais, TC; Pereira, GDAV; Pessoa, RS, 2023)
"Previous studies have examined maternal melatonin implants in fall calving Mississippi cattle during the third trimester of pregnancy."4.31Effects of prenatal and postnatal melatonin supplementation on overall performance, male reproductive performance, and testicular hemodynamics in beef cattle. ( Burnett, DD; Geary, TW; Lemley, CO; Messman, RD; Reid, DS; Van Emon, ML; Waterman, RC; Zezeski, AL, 2023)
"In the third trimester of pregnancy, women with TPL suffer from poorer sleep quality and disruption of circadian rhythm of melatonin secretion compared with NPW."4.31Mental health, sleep quality, and hormonal circadian rhythms in pregnant women with threatened preterm labor: a prospective observational study. ( Chen, N; Chen, TT; Hu, RF; Huang, L; Huang, SX; Li, XT; Liu, GH; Wang, XJ, 2023)
"Our findings suggest that disruptions or a lack of melatonin during pregnancy may cause changes in craniofacial and dental development, at least in animal experiments; however, in humans, these feedings are still poorly understood, and thus careful evaluations of melatonin levels in humans need to be investigated in craniofacial alterations."4.31Absence of melatonin during development impairs craniofacial and dental onset in rats. ( Bortolança, TJ; Calsa, B; Catisti, R; de Camargo, LS; de Oliveira, CA; do Amaral, FG; Santamaria-Jr, M, 2023)
" Methadone is recommended for the treatment of opioid use disorders during pregnancy, increasing the number of children prenatally exposed to long-acting opioids."4.31Methadone administered to rat dams during pregnancy and lactation affects the circadian rhythms of their pups. ( Bendová, Z; Novotný, J; Pačesová, D; Spišská, V, 2023)
"Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)."4.21 ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; 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Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022)
"Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and molecular levels, this study investigated whether maternal treatment with melatonin protects against programmed cardiovascular dysfunction in the offspring using an established rodent model of hypoxic pregnancy."4.12Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy. ( Blanco, CE; Camm, EJ; Galli, GLJ; Giussani, DA; Hansell, JA; Herrera, EA; Lock, MC; Patey, OV; Richter, HG; Trafford, AW; Villamor, E, 2022)
"An oral treatment with melatonin during pregnancy promotes postnatal cerebral perfusion in chronically hypoxic neonates."4.12Melatonin treatment during chronic hypoxic gestation improves neonatal cerebrovascular function. ( Arias, PV; Candia, AA; Ebensperger, G; González-Candia, A; González-Candia, C; Herrera, EA; Llanos, AJ; Navarrete, A; Reyes, RV, 2022)
" Supplementing dietary melatonin during a compromised pregnancy increased uteroplacental blood flow and prevented IUGR in a seasonal-dependent manner."4.12Seasonal and temporal variation in the placenta during melatonin supplementation in a bovine compromised pregnancy model. ( Burnett, DD; Cochran, T; Contreras-Correa, ZE; Lemley, CO; Metcalfe, A, 2022)
"Acute toxoplasmosis during pregnancy increases the risk of abortion through reduction of maternal serum melatonin level and dysregulation of pro-inflammatory/inflammatory cytokines axis."4.02Are alterations in melatonin and inflammatory cytokine serum levels linked with recurrent abortion in pregnant women with acute toxoplasmosis: The interacted nexus. ( Al-Kuraishi, AH; Al-Kuraishy, HM; Hasan, HH; Khalil, HI, 2021)
"Melatonin and interleukin -10 were significantly lower in subjects with intrahepatic cholestasis of pregnancy (p=0."4.02The Role of Melatonin, IL-8 and IL-10 in Intrahepatic Cholestasis of Pregnancy. ( Çalışkan, C; Çelik, S; Guve, H, 2021)
" Melatonin is involved in the outcome of normal pregnancy."4.02Impact of Melatonin on Full-Term Fetal Brain Development and Transforming Growth Factor-β Level in a Rat Model of Preeclampsia. ( Aref, M; El-Malkey, NF; Emam, H; Khalil, SS, 2021)
"The objectives were to examine melatonin-mediated changes in temporal uterine blood flow (UBF), vaginal temperatures (VTs), and fetal morphometrics in 54 commercial Brangus heifers (Fall, n = 29; Summer, n = 25) during compromised pregnancy."4.02Melatonin alters bovine uterine artery hemodynamics, vaginal temperatures, and fetal morphometrics during late gestational nutrient restriction in a season-dependent manner. ( Burnett, DD; Contreras-Correa, ZE; Heath King, E; Lemley, CO; Messman, RD; Sánchez-Rodríguez, HL; Sidelinger, DR, 2021)
"We investigated the effects of melatonin on rats with induced hypothyroidism during gestation as well as its effect on the development of the gonads of their offspring."3.96Effect of melatonin on gonad and thyroid development of offspring of hypothyroid pregnant rats. ( Alves, RDC; Baptista, MGP; D Assunção, CG; de Albuquerque, YML; Ferreira, CGM; Teixeira, ÁAC; Wanderley Teixeira, V, 2020)
"Inflammation is associated with injury to immature lungs, and melatonin administration to preterm newborns with acute respiratory distress improves pulmonary outcomes."3.96Melatonin for prevention of fetal lung injury associated with intrauterine inflammation and for improvement of lung maturation. ( Burd, I; Chudnovets, A; Kang, Y; Lee, JY; Lei, J; Na, Q; Shin, HE; Shin, NE; Song, H, 2020)
"Several novel animal studies have shown that intrauterine metabolic programming can be modified in the event of reduced melatonin synthesis during pregnancy, leading to glucose intolerance and insulin resistance in the offspring."3.91Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring. ( Amaral, F; Cipolla-Neto, J; Lowden, A; Moreno, CRC; Nehme, PA; Skene, DJ, 2019)
"Maternally administered melatonin modulated immune responses to maternal inflammation and decreased preterm birth and perinatal brain injury."3.91Administration of melatonin for prevention of preterm birth and fetal brain injury associated with premature birth in a mouse model. ( Burd, I; Dash, O; Hwang, JY; Lee, JY; Lei, J; McLane, MW; Park, M; Shin, NE; Song, H, 2019)
" The seasonal changes in serum prolactin levels correlated positively with circulating progesterone (P) level, but inversely with circulating melatonin level during first pregnancy showing delayed development in Cynopterus sphinx."3.85Prolactin modulates luteal activity in the short-nosed fruit bat, Cynopterus sphinx during delayed embryonic development. ( Krishna, A, 2017)
"Hypertension can originate from early-life insults, whereas maternal melatonin therapy can be protective in a variety of models of programmed hypertension."3.85Maternal melatonin or agomelatine therapy prevents programmed hypertension in male offspring of mother exposed to continuous light. ( Chan, JYH; Hsu, CN; Lee, CT; Lin, YJ; Tain, YL, 2017)
" Melatonin, which transmits information to regulate the sleep-wake rhythm and other such biorhythms, has been implicated in insulin resistance, antioxidant behaviors, and metabolic syndrome."3.83Salivary melatonin levels and sleep-wake rhythms in pregnant women with hypertensive and glucose metabolic disorders: A prospective analysis. ( Hayase, M; Samejima, M; Seki, H; Shimada, M; Shirai, F, 2016)
" In this scenario, melatonin acts as an umbilical vasodilator and a potent antioxidant that has not been evaluated in pregnancies under chronic hypoxia that induce fetal growth restriction."3.83Potential adverse effects of antenatal melatonin as a treatment for intrauterine growth restriction: findings in pregnant sheep. ( Araya, C; Ebensperger, G; González-Candia, A; Herrera, EA; Llanos, AJ; Quezada, S; Reyes, RV; Serón-Ferré, M; Veliz, M, 2016)
"Melatonin was effective in the treatment of experimental endometriosis induced in SCID mice."3.83The effects of melatonin on endometriotic lesions induced by implanting human endometriotic cells in the first SCID-mouse endometriosis-model developed in Turkey. ( Akkaya, H; Attar, R; Ozkan, F; Yesildaglar, N; Yildirim, G; Yildirim, OK; Yilmaz, B, 2016)
"Our results indicated that antioxidant therapy, by melatonin or N-acetylcysteine, in pregnant rats with nitric oxide deficiency can prevent programmed hypertension in male adult offspring."3.83Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N ( Chan, JY; Hsu, CN; Lee, CT; Tain, YL, 2016)
" We sought to address these questions by 1) feeding pregnant rats with diets sufficient or deficient in DHA during gestation and lactation; 2) weaning their male offspring to diets that were sufficient or deficient in DHA; and 3) assessing depression-related behaviors (forced swim test), plasma biomarkers [brain-derived neurotrophic factor (BDNF), serotonin, and melatonin], and brain biomarkers (BDNF) in the offspring before and after puberty."3.81Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats. ( Butt, CM; Salem, N; Weiser, MJ; Wynalda, K, 2015)
"Experimental studies in animal models supporting protective effects on the fetus of melatonin in adverse pregnancy have prompted clinical trials in human pregnancy complicated by fetal growth restriction."3.81Melatonin modulates the fetal cardiovascular defense response to acute hypoxia. ( Allison, BJ; Botting, KJ; Giussani, DA; Herrera, EA; Niu, Y; Serón-Ferré, M; Thakor, AS, 2015)
"The aim of this study was to observe the influence of interfered circadian rhythm on pregnancy of rats and growth of neonatal rats, and to explore the relationship between the interfered circadian rhythm and the changes of melatonin and progesterone."3.81[The influence of interfered circadian rhythm on pregnancy and neonatal rats]. ( Chen, WJ; Guo, YH; Sheng, WJ; Tan, Y, 2015)
" We hypothesized that melatonin supplementation in a compromised pregnancy enhances the bradykinin (BK)-induced relaxations of placental arteries thereby ensuring sufficient umbilical blood flow to the developing fetus."3.80Effect of maternal nutrient restriction and melatonin supplementation from mid to late gestation on vascular reactivity of maternal and fetal placental arteries. ( Dubey, N; Lemley, CO; Meyer, AM; O'Rourke, ST; Shukla, P; Vonnahme, KA, 2014)
" The numbers of matured follicles and retrieved oocytes, fertilization rates, implantation rates, clinical pregnancy rate, and intrafollicular concentrations of TNFα, 8-hydroxy-2'-deoxyguanosine (8-OHdG) and hexanoyl-lysine adduct (HEL) as oxidative stress markers, and melatonin and Cu,Zu-superoxide dismutase (Cu,Zn-SOD) as antioxidants were compared between the two groups."3.80A pilot study to search possible mechanisms of ultralong gonadotropin-releasing hormone agonist therapy in IVF-ET patients with endometriosis. ( Nakamura, Y; Numa, F; Sugino, N; Takasaki, A; Tamura, H, 2014)
"In order to show that a combination of melatonin and prostaglandins may be useful to save lives, we use newborn rat as a model of necrotizing enterocolitis to test the hypothesis of using the combination therapy might have more potential effect on mucosal cytoprotection and healing."3.79Evaluation of melatonin and prostaglandin E1 combination on necrotizing enterocolitis model in neonatal rats. ( Canpolat, FE; Cekmez, F; Cetinkaya, M; Kafa, IM; Sarıcı, SÜ; Tayman, C; Tunc, T; Uysal, S, 2013)
"Although melatonin supplementation is known to influence numerous physiological functions, little is however known of its effects on pregnancy outcome."3.79Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats. ( Gupalo, S; Omar, E; Saleh, HI; Singh, HJ, 2013)
"The purpose of this study was to investigate whether prophylactic administration of melatonin to the mother throughout pregnancy could protect against ischemia/reperfusion (I/R)-induced oxidative brain damage in neonatal rats."3.78Prophylactic administration of melatonin to the mother throughout pregnancy can protect against oxidative cerebral damage in neonatal rats. ( Fukaya, T; Hamada, F; Hayashi, Y; Imamura, R; Nagai, R; Shinohara, K; Wakatsuki, A; Watanabe, K, 2012)
"Although melatonin lowers blood pressure in spontaneously hypertensive rats (SHR), its effect following antenatal and postpartum supplementation on the subsequent development of hypertension in SHR pups remains unknown."3.77Effects of antenatal, postpartum and post-weaning melatonin supplementation on blood pressure and renal antioxidant enzyme activities in spontaneously hypertensive rats. ( Lee, SK; Singh, HJ; Sirajudeen, KN; Sundaram, A; Zakaria, R, 2011)
"The effect of pinealectomy (PIN-X) and PIN-X+melatonin treatment during pregnancy (PIN-X+MEL) 100μg/100g body weight on Substance P (SP) in the striatum was investigated in offspring female rats."3.77Seasonal variations of Substance P in the striatum of the female rat are affected by maternal and offspring pinealectomy. ( Debeljuk, L; Díaz, B; Díaz, E; Durand, D; Fernández, C; Lasaga, M; Vázquez, N, 2011)
"Lactotrophs in pituitary pars distalis (PD) of viscacha were studied by immunohistochemistry and morphometric analysis in the following groups: 1) adult males throughout the reproductive cycle (reproductive, gonadal regression, and recovery periods), 2) melatonin-treated adults, 3) castrated adults, 4) prepubertal, 5) non-pregnant females, and 6) pregnant females (early, mid, and late pregnancy)."3.76Morphological and morphometric changes of pituitary lactotrophs of viscacha (Lagostomus maximus maximus) in relation to reproductive cycle, age, and sex. ( Filippa, V; Mohamed, F, 2010)
" After weaning, dams were tested for anxiety, sleep recording or hormone profiling (ACTH, corticosterone and prolactin) and brain sampling (pineal melatonin and hippocampus serotonin)."3.76Neonatal arthritis disturbs sleep and behaviour of adult rat offspring and their dams. ( Andersen, ML; Bignotto, M; D'Almeida, V; Martins, PJ; Roizenblatt, S; Tufik, S, 2010)
" The rats were assigned to mother groups on day 10 of pregnancy: control (12-h light/dark), LL (light from day 10 to 21 of pregnancy), and LL+Mel (LL and sc injection to the mothers of a daily dose of melatonin, 1 mg/kg body weight at circadian time 12, from day 17 to 21 of pregnancy)."3.76Protective effect of maternal prenatal melatonin administration on rat pups born to mothers submitted to constant light during gestation. ( Cisternas, CD; Compagnucci, MV; Conti, NR; Ponce, RH; Vermouth, NT, 2010)
"Female Swiss Albino rats were divided into five groups: intact control group; saline control group; epilepsy group; epilepsy plus Px group; and melatonin-treated epilepsy plus Px group."3.74Efficacy of melatonin on offspring liver maturation in pinealectomized pregnant rats subjected to experimental epilepsy. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yavaşoğlu, A; Yurtseven, M, 2007)
" The aim of this study was to investigate the protective effects in rat maternal and fetal livers as also the placenta of melatonin or silymarin against the oxidative stress and apoptosis induced by maternal obstructive cholestasis during the last third of pregnancy (OCP)."3.74Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio. ( Castaño, B; Gonzalez-Buitrago, JM; Marin, JJ; Perez, MJ, 2007)
"Depression during pregnancy is frequently treated with the selective serotonin reuptake inhibitor (SSRI), fluoxetine (FX), commonly known as Prozac (Eli Lilly & Co, Indianapolis, IN)."3.73Maternal fluoxetine infusion does not alter fetal endocrine and biophysical circadian rhythms in pregnant sheep. ( Chien, C; Gruber, N; Kennaway, DJ; McMillen, IC; Morrison, JL; Riggs, KW; Rurak, DW, 2005)
"In this study, rats were randomly divided into four groups (ten animals each): intact control group, epilepsy control group, surgical pinealectomy + epilepsy group, and group with melatonin treatment following pinealectomy procedure."3.73Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yurtseven, ME, 2006)
"Three groups of four primiparous Holstein-Friesian heifers were fed throughout pregnancy either a control diet or that diet supplemented with either 5 to 6 g per day of rumen-protected intestinally available methionine or 25 mg melatonin."3.73Effects of supplementing pregnant heifers with methionine or melatonin on the anatomy and other characteristics of their lateral hind claws. ( Galbraith, H; Hendry, KA; Knight, CH; Omand, T; Rae, M; Wilde, CJ, 2006)
"The present pre- and postnatal study was carried out to investigate the effect of melatonin (MEL), a potent antioxidant, on biochemical variables in the in vivo model of intrauterine hypoxia in rats."3.72Effect of melatonin on biochemical variables induced by phenytoin in organs of mothers, foetuses and offsprings of rats. ( Dubovický, M; Mach, M; Navarová, J; Ujházy, E, 2004)
"The aim of the present study was to test the hypothesis that the natural antioxidant melatonin (MEL) and the synthetic antioxidant stobadine (STO) could reduce the incidence of maternal and embryofoetal toxicity in rats due to intrauterine hypoxia."3.72Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration. ( Brucknerová, I; Dubovický, M; Juránek, I; Mach, M; Navarová, J; Soltés, L; Ujházy, E; Zeman, M, 2004)
"The concentrations of neurokinin A (NKA) and substance P (SP), members of tachykinins family, have been studied in all seasons of the year in frontal cortex, striatum and testes of male offspring 21-, 31-, or 60 days old of mother Wistar rats: control, pinealectomized (PIN-X) and pinealectomized + melatonin during pregnancy (PIN- X + MEL) kept under 12h:12h L:D."3.72Seasonal changes of SP and NKA in frontal cortex, striatum and testes in the rat. Role of maternal pineal gland. ( Debeljuk, L; Díaz López, B; Díaz Rodríguez, E; Fernández Alvarez, C; Vázquez Moreno, N, 2004)
"We assessed the correlation between the rhythm of melatonin concentration and circadian blood pressure patterns in normal and hypertensive pregnancy."3.72Circadian melatonin concentration rhythm is lost in pregnant women with altered blood pressure rhythm. ( Garbati, E; Giannubilo, SR; Tranquilli, AL; Turi, A, 2004)
"We evaluated whether melatonin administration to pregnant rats during the final week of pregnancy affects prepubertal secretion of luteinizing hormone (LH), follicle stimulating hormone (FSH), and prolactin in offspring."3.71Effect of prenatal melatonin exposure on gonadotropins and prolactin secretion in male and female rat pups. ( Miyahara, Y; Okatani, Y; Otukonyong, EE; Wakatsuki, A, 2001)
"The effects of maternal melatonin on fetal and neonatal melatonin and dopamine D1 receptor systems in the central nervous system, mainly in the suprachiasmatic nuclei (SCN), were investigated after pinealectomy of rats at day 7 of pregnancy."3.70Alteration by maternal pinealectomy of fetal and neonatal melatonin and dopamine D1 receptor binding in the suprachiasmatic nuclei. ( Imai-Matsumura, K; Kobayashi, K; Matsumura, K; Miyake, Y; Murai, I; Naitoh, N; Ohtuka, H; Satoh, K; Takagi, K; Watanabe, Y, 1998)
"To investigate whether melatonin reduces the susceptibility of the fetal rat brain to oxidative damage of lipids and DNA, we created a model of fetal ischemia/reperfusion using rats at day 19 of pregnancy."3.70Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999)
"Three groups of female Wistar rats were used: control, PIN-X, and those treated (250 micrograms/100 g body weight) with melatonin throughout pregnancy."3.69Maternal pineal gland participates in prepubertal rats' ovarian oocyte development. ( Colmenero, MD; Díaz, B; Díaz, E; Fernández, B, 1995)
"The influence of pineal gland function and of melatonin during pregnancy upon sexual maturation of female offspring in rats was examined."3.68Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat. ( Colmenero, MD; Díaz, B; Esquifino, A; González, ML; Marín, B; Miguel, JL, 1991)
"We have investigated the effect of pinealectomy of ewes in pregnancy on the presence of the diurnal rhythm in fetal and maternal plasma concentrations of melatonin."3.67Maternal pinealectomy abolishes the diurnal rhythm in plasma melatonin concentrations in the fetal sheep and pregnant ewe during late gestation. ( McMillen, IC; Nowak, R, 1989)
"Concentrations of melatonin have been measured in amniotic fluid obtained during late pregnancy and labour."3.66Melatonin in amniotic fluid during human parturition. ( Anderson, AB; Keirse, MJ; Mitchell, MD; Sayers, L; Turnbull, AC, 1978)
"The concentration of melatonin in maternal peripheral plasma was measured during late pregnancy, term and pre-term labour."3.66Melatonin in the maternal and umbilical circulations during human parturition. ( Anderson, AB; Bibby, JG; Mitchell, MD; Sayers, L; Turnbull, AC, 1979)
"Melatonin is a natural neuroprotective hormone, which makes it promising for the treatment of neurodegeneration after asphyxia."3.01Melatonin: A Potential Candidate for the Treatment of Experimental and Clinical Perinatal Asphyxia. ( Furmaga-Jabłońska, W; Januszewski, S; Pluta, R; Tarkowska, A, 2023)
"Gestational diabetes mellitus is an important public health problem and has been associated with the development of pregnancy-specific urinary incontinence."3.01Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with gestational diabetes mellitus. ( Barbosa, AMP; França, DCH; França, EL; Honorio-França, AC; Rudge, MVC; Sobrevia, L, 2023)
"Melatonin has been shown to have anti-oxidant/anti-inflammatory effects and to reduce brain damage, mainly after hypoxic ischemic encephalopathy."3.01Oral melatonin as a new tool for neuroprotection in preterm newborns: study protocol for a randomized controlled trial. ( Accorsi, P; Angelini, M; Aversa, S; Caporali, C; Cociglio, S; De Silvestri, A; Fazzi, E; Garofoli, F; Longo, S; Orcesi, S; Pisoni, C; Rizzo, V; Tzialla, C; Zecca, M, 2021)
"Melatonin is an immunomodulatory factor and there is evidence that it has a direct effect on IgG production."2.94Exogenous melatonin and male foetuses improve the quality of sheep colostrum. ( Abecia, JA; García, AI; Garrido, C; Gave, M; López, D; Luis, S; Mata, L; Valares, JA, 2020)
"Melatonin therapy was safe for mothers and their fetuses."2.87Melatonin improves endothelial function in vitro and prolongs pregnancy in women with early-onset preeclampsia. ( Alers, NO; Gurusinghe, S; Hobson, SR; Kingdom, JC; Lim, R; Miller, SL; Wallace, EM, 2018)
"The melatonin treatments were performed on 10th February; 10th March; 10th April and on 10th May each time in 4 different randomly selected farms."2.84Melatonin treatment in winter and spring and reproductive recovery in Sarda breed sheep. ( Carcangiu, V; Daga, C; Di Stefano, MV; Farci, F; Luridiana, S; Mura, MC; Pulinas, L; Starič, J, 2017)
"Placental insufficiency affects about 10% of pregnancies and can lead to pre-eclampsia, fetal growth restriction, and preterm birth."2.82The role of melatonin in pregnancies complicated by placental insufficiency: A systematic review. ( Bussolaro, S; Fantasia, I; Rolnik, DL; Stampalija, T, 2022)
"Melatonin is a known antioxidant and preclinical studies have shown its ability to modulate reproductive function through hormonal and immune system regulation and sperm cell proliferation."2.82Coenzyme Q10 and Melatonin for the Treatment of Male Infertility: A Narrative Review. ( Boeri, L; Fulgheri, I; Gadda, F; Jannello, LMI; Lucignani, G; Montanari, E; Silvani, C; Somigliana, E; Turetti, M; Viganò, P, 2022)
"Melatonin treatment resulted in an increase (P < 0."2.82Manipulation of reproductive performance of lactating buffaloes using melatonin and controlled internal drug release device treatment during out-of-breeding season under tropical conditions. ( Balhara, AK; Ghuman, SS; Phulia, SK; Ramadan, TA; Sharma, RK; Singh, I, 2016)
"Fetal intrauterine growth restriction (IUGR) is a serious pregnancy complication associated with increased rates of perinatal morbidity and mortality, and ultimately with long-term neurodevelopmental impairments."2.79Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction. ( Alers, NO; Castillo-Melendez, M; Drummond, GR; Jenkin, G; Loose, JM; Miller, SL; Sabaretnam, T; Supramaniam, VG; VanZyl, N; Walker, DW; Wallace, EM; Yawno, T, 2014)
" We present a proposal for a pilot double-blind randomised placebo-controlled dose-response trial aimed to determine whether oral melatonin supplementation during ovarian stimulation can improve the outcomes of assisted reproductive technology."2.79A pilot double-blind randomised placebo-controlled dose-response trial assessing the effects of melatonin on infertility treatment (MIART): study protocol. ( Fernando, S; Osianlis, T; Rombauts, L; Vollenhoven, B; Wallace, E, 2014)
"Melatonin treatment tended to increase the percentage of positive cells to PR in deep glandular epithelium, independently of diet (P=0."2.78Effect of exogenous melatonin on embryo viability and uterine environment in undernourished ewes. ( Abecia, JA; Casao, A; Fernández-Foren, A; Forcada, F; Meikle, A; Sartore, I; Sosa, C; Vázquez, MI, 2013)
"IVF patients with sleep disorders may benefit from melatonin administration in improving the oocyte and the embryo quality, but the sleeping problem itself may not be fixed."2.76Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems. ( Aksakal, FN; Cicek, N; Devran, A; Eryilmaz, OG; Mollamahmutoğlu, L; Sarikaya, E, 2011)
" After 15 days, the 40 mg dosage was decreased to 20mg/kg body weight for an additional 20 days (35 days of PTU)."2.73Serum thyroid hormones and performance of offspring in ewes receiving propylthiouracil with or without melatonin. ( Duffey, JL; Gifford, CA; Hallford, DM; Knight, RL, 2007)
"Intrauterine inflammation is shown to be associated with preterm birth, fetal inflammatory response syndrome, and other pregnancy-related comorbidities such as central nervous system diseases including cerebral palsy and periventricular leukomalacia, pulmonary diseases such as bronchopulmonary dysplasia and respiratory distress syndrome, and necrotizing enterocolitis, to name a few."2.72Melatonin for the prevention of fetal injury associated with intrauterine inflammation. ( Kim, JM; Lee, JY; Lee, SY, 2021)
"Human pregnancy is a sequence of events finely tuned by several molecular interactions that come with a new birth."2.72Melatonin and Myo-Inositol: Supporting Reproduction from the Oocyte to Birth. ( Forte, G; Laganà, AS; Montanino Oliva, M; Russo, M; Unfer, V, 2021)
"Ten pregnant women with DSM-IV major depressive disorder were randomly assigned from April 2000 to January 2002 to a 5-week clinical trial with either a 7000 lux (active) or 500 lux (placebo) light box."2.71Randomized clinical trial of bright light therapy for antepartum depression: preliminary findings. ( Epperson, CN; Hanusa, BH; Oren, DA; Peindl, KS; Terman, JS; Terman, M; Wisner, KL, 2004)
"Pregnancy is well-known to increase the oxidative stress, mainly produced by a normal systemic inflammatory response, which results in high amounts of circulating reactive oxygen species (ROS) and reactive nitrogen species (RNS)."2.66Oxidative stress: Normal pregnancy versus preeclampsia. ( Abad, C; Chiarello, DI; Marín, R; Mate, A; Rojas, D; Sobrevia, L; Toledo, F; Vázquez, CM, 2020)
" Challenges include timing, dosing and administration route for each neuroprotectant."2.61Novel interventions to reduce oxidative-stress related brain injury in neonatal asphyxia. ( Cheung, PY; Schmölzer, GM; Solevåg, AL, 2019)
" Melatonin-containing supplements are easily found in online and high street retailers, and despite its supplementation deemed to be relatively safe, no consensus has been reached on effective dosage and supplementation period."2.61The usefulness of melatonin in the field of obstetrics and gynecology. ( Bueno, AA; Genario, R; Morello, E; Santos, HO, 2019)
"Melatonin is a lipophilic hormone synthesized and secreted mainly in the pineal gland, acting as a neuroendocrine transducer of photoperiodic information during the night."2.58From Implantation to Birth: Insight into Molecular Melatonin Functions. ( Carlomagno, G; Minini, M; Tilotta, M; Unfer, V, 2018)
" It has been postulated that melatonin induces specific biochemical responses that regulate cell proliferation in fetuses, and that its antioxidant action promotes bioavailability of nitric oxide and, thus, placental perfusion and also fetal nutrition and oxygenation."2.58Melatonin treatment in fetal and neonatal diseases. ( Bernardes, N; de Paula Antunes Teixeira, V; Dos Reis, MA; Etchebehere, RM; Galvão Petrini, C; Gonçalves Dos Reis Monteiro, ML; Machado, JR; Meirelles, MF; Miranda Corrêa, RR; Penna Rocha, L; Rodrigues Helmo, F; Souza de Oliveira Guimarães, C, 2018)
" This review details the adverse effects of IUGR on fetal brain development and discusses intervention strategies."2.53Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions. ( Fu, W; Liu, J; Wang, Y, 2016)
"Melatonin is an important neuroprotective factor and its receptors are expressed in the fetal brain."2.53Melatonin in Pregnancy: Effects on Brain Development and CNS Programming Disorders. ( Assunção Salustiano, EM; Sagrillo-Fagundes, L; Soliman, A; Vaillancourt, C; Yen, PW, 2016)
"Melatonin has proven to be a potentially useful therapeutic tool in the reduction of graft rejection."2.53Potential benefits of melatonin in organ transplantation: a review. ( Alatorre-Jiménez, MA; Esteban-Zubero, E; García, JJ; García-Gil, FA; Iñigo-Gil, P; López-Pingarrón, L; Reiter, RJ; Tan, DX, 2016)
"Melatonin is a powerful antioxidant which has an essential role in controlling several physiological reactions, as well as biological rhythms throughout human reproductive life."2.52Melatonin: a "Higgs boson" in human reproduction. ( Dikic, S; Dobrosavljevic, A; Dragojevic Dikic, S; Jovanovic, AM; Jovanovic, T; Jurisic, A, 2015)
" The potential sensitivity of developing organism to the effects of radiofrequency (RF) signals, the higher estimated specific absorption rate (SAR) values of children and greater lifetime cumulative risk raised the scientific interest for children's vulnerability to electromagnetic fields (EMFs)."2.52The Effects of Electromagnetic Field on the Endocrine System in Children and Adolescents. ( Büyükgebiz, A; Çömlekçi, S; Dündar, B; Sangün, Ö, 2015)
"Melatonin treatment, alterations of the normal light:dark cycle and light exposure at night."2.50Melatonin and the circadian system: contributions to successful female reproduction. ( Reiter, RJ; Tamura, H; Tan, DX; Xu, XY, 2014)
"Melatonin is an endogenously produced indoleamine and secreted by the pineal gland."2.50Transcriptional regulation of programmed hypertension by melatonin: an epigenetic perspective. ( Chan, JY; Huang, LT; Tain, YL, 2014)
"Treatment with melatonin might result in a wide range of health benefits, including improved quality of life and reduced healthcare costs."2.48Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period. ( Aversa, S; Barberi, I; Gitto, E; Pellegrino, S; Reiter, RJ, 2012)
"Melatonin is a highly effective antioxidant, free radical scavenger, and has anti-inflammatory effect."2.48Melatonin utility in neonates and children. ( Chen, YC; Huang, LT; Sheen, JM; Tain, YL, 2012)
"Melatonin has clear acute and delayed effects on sleep and circadian rhythms."2.40Treatment of circadian rhythm disorders--melatonin. ( Arendt, J; Deacon, S, 1997)
" However, in normal healthy adults over 18 years old, not pregnant or lactating, with no personal or family histories of psychiatric disorder, and unmedicated except for oral contraceptives and minor analgesics (if necessary), the only significant short-term side effect in the author's experience has been sleepiness following oral ingestion of synthetic melatonin (5 mg or less, oral fast release), licensed for human experimental use and for prescription on a named-patient basis."2.40Safety of melatonin in long-term use (?) ( Arendt, J, 1997)
" There is little information on the potential adverse effects of melatonin ingestion in humans."2.40Reproductive safety of melatonin: a "wonder drug" to wonder about. ( Weaver, DR, 1997)
"Menopause is associated with a reduction in melatonin which may relate to the changing gonadotropin levels."2.40Melatonin and human reproduction. ( Reiter, RJ, 1998)
"Melatonin is a principal hormone of the vertebrate pineal gland."2.40[Melatonin and its role the circadian function]. ( Nowak, JZ; Zawilska, JB, 1999)
"In women who developed preeclampsia during pregnancy, circadian oscillations of placental macrophages were lost and could not be rescued by coculture with trophoblasts from healthy women."1.91Disruption of the Expression of the Placental Clock and Melatonin Genes in Preeclampsia. ( Bretelle, F; Coiffard, B; Desbriere, R; Diallo, AB; Donato, X; Katsogiannou, M; Mege, JL; Mezouar, S, 2023)
"Melatonin treatment, however, improved their nursing behaviour and reduced their plasma corticosterone levels."1.91Postnatal melatonin administration to stressed dams for ameliorating risk-taking behaviour in rat pups through maternal care improvement. ( Bagheri, F; Goudarzi, I, 2023)
"Melatonin (MLT) is a promising antioxidant that can be used for reproductive protection."1.91Melatonin alleviates cisplatin-induced mice spermatogenesis defects. ( Jun, LF; Lin, WZ; Nan, LY; Peng, Z; Sheng, ZY; Xia, LX; Xin, WZ; Zi, T, 2023)
"The study involved 32 women with preeclampsia and 33 healthy pregnant women as a control group."1.91Changes in concentrations of melatonin, PlGF, and cytokines in women with preeclampsia. ( Mykhailovych Barbe, A; Mykhailovych Yuzko, O; Mykolaiovych Berbets, A; Radu, MR; Savka, RF, 2023)
"Treatment with melatonin restored the HI-induced effects on miR-126/miR-146a expressions, both in the cerebral cortex and in serum."1.91MiR-126 and miR-146a as Melatonin-Responsive Biomarkers for Neonatal Brain Ischemia. ( Albertini, MC; Balduini, W; Buonocore, G; Carloni, S; Dell'Orto, V; Perrone, S; Vanzolini, T; Weiss, MD, 2023)
"Corticosterone levels were comparable between the two groups, although ACTH levels were elevated significantly in the sleep deprivation group."1.91Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague-Dawley rats. ( Li, B; Li, J; Liu, S; Peng, X; Shi, J; Zhong, H; Zhou, X, 2023)
"Melatonin was administered in daily injections of 0."1.72Melatonin Administration Prevents Placental and Fetal Changes Induced by Gestational Diabetes. ( Alves, ÉR; D'Assunção, CG; de Albuquerque, YML; de Melo, IMF; Ferreira, CGM; Neto, CJCL; Teixeira, ÁAC; Wanderley Teixeira, V, 2022)
"Melatonin may inhibit HtrA1 transcription through the miR-520c-3p/SETD7 axis to promote trophoblast invasion and migration and reduce trophoblast pyroptosis in PE."1.72Melatonin regulates trophoblast pyroptosis, invasion and migration in preeclampsia by inhibiting HtrA1 transcription through the microRNA-520c-3p/SETD7 axis. ( Chang, J; Chen, B; Feng, L; Liu, Z; Zhao, X, 2022)
"Hexavalent chromium Cr(VI) is a well-known environmental toxic metal that causes reprotoxicity in pregnant females."1.72New insights into the reverse of chromium-induced reprotoxicity of pregnant mice by melatonin. ( Ding, JJ; Guo, HX; Han, JQ; Huang, YN; Jiao, C; Ma, XY; Qi, YL; Xu, J; Yuan, QQ, 2022)
"Melatonin is an endogenous hormone and can restore gut microbial dysbiosis under various disease conditions."1.72Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism. ( Cui, Y; Li, XG; Liu, W; Liu, X; Qiu, B; Wang, X; Xiang, G; Yu, M; Zhang, D; Zhang, Y, 2022)
"Melatonin (5 mg/kg) was injected i."1.62Partial protective effects of melatonin on developing brain in a rat model of chorioamnionitis. ( Bodard, S; Chalon, S; Favrais, G; Gressens, P; Gulhan, Z; Saliba, E; Savary, L, 2021)
"Co-treatment with melatonin alleviated B(a)P or BPDE-induced CL dysfunction by ameliorating oxidative stress, counteracting phosphorylation of PI3K/AKT/GSK3β signaling pathway, decreasing the apoptosis of the ovarian cells."1.62Melatonin alleviates benzo(a)pyrene-induced ovarian corpus luteum dysfunction by suppressing excessive oxidative stress and apoptosis. ( Chen, X; Ding, Y; Gao, R; Geng, Y; He, J; Li, N; Liu, X; Mu, X; Tan, Q; Wang, Y; Xu, H, 2021)
"However, the effect of melatonin on gestational hypertension (GH) and the underlying mechanism remain unclear."1.62Melatonin ameliorates hypertension in hypertensive pregnant mice and suppresses the hypertension-induced decrease in Ca ( Liu, F; Sun, Y; Wang, C; Zhang, N, 2021)
"Treatment with melatonin increased superoxide dismutase and glutathione peroxidase activities and decreased malondialdehyde concentrations but did not significantly affect the concentration of P4."1.62Two melatonin treatments improve the conception rate after fixed-time artificial insemination in beef heifers following synchronisation of oestrous cycles using the CoSynch-56 protocol. ( Gao, X; Guo, L; Li, M; Lu, W; Wang, J; Yang, Y; Zhao, J, 2021)
"Melatonin is a hormone and antioxidant produced by the pineal gland and placenta."1.62Melatonin, a Potential Therapeutic Agent for Preeclampsia, Reduces the Extrusion of Toxic Extracellular Vesicles from Preeclamptic Placentae. ( Chamley, L; Chen, Q; Groom, K; Tang, Y, 2021)
"Melatonin was administered daily in drinking water (4 mg/kg b."1.56Melatonin mitigates hippocampal and cognitive impairments caused by prenatal irradiation. ( Jendželovský, R; Kisková, T; Pipová Kokošová, N; Račeková, E; Šmajda, B; Štafuriková, A; Vilhanová, K, 2020)
"Melatonin was added during the preimplantation development period."1.56Melatonin Protects Rabbit Somatic Cell Nuclear Transfer (SCNT) Embryos from Electrofusion Damage. ( Dong, Y; Du, Y; Fu, S; Guo, S; Hu, F; Liu, E; Luo, S; Qin, H; Qu, P; Shen, C; Xue, Y, 2020)
"Melatonin powder was dissolved in dimethyl sulfoxide (DMSO) and olive oil and injected in two dose of 25 mg (MEL-1; n = 10) and 50 mg (MEL-2; n = 10) in May."1.56Higher doses of Melatonin affect ovarian and middle uterine arteries vascular blood flow and induce oestrus earlier in acyclic ewes. ( Abdelnaby, EA, 2020)
"Melatonin treatment also reduced sFlt-1, increased PlGF, and decreased the sFlt-1/PlGF ratio."1.56Melatonin attenuates hypertension and oxidative stress in a rat model of L-NAME-induced gestational hypertension. ( Jiang, Z; Zuo, J, 2020)
"Melatonin treatment provided significant therapeutic effects on fetal hearts via regulating all these stress response at cellular and molecular levels."1.56Melatonin regulates oxidative stress and apoptosis in fetal hearts of pinealectomised RUPP rats. ( Demir, U; Doğan, A; Doğanlar, O; Doğanlar, ZB; Güçlü, O; Ovali, MA; Uzun, M, 2020)
"Treatment with melatonin significantly reduced cypermethrin-induced genetic damage in dams and pups; however, melatonin was not effective against the genetic damage caused by methomyl."1.51Genotoxic and mutagenic evaluation of the protective effect of exogenous melatonin in adult rats and their offspring exposed to the insecticides methomyl and cypermethrin during pregnancy. ( Chagas, CA; Coelho Teixeira, ÁA; da Silva, MA; de Sousa Coelho, IDD; do Nascimento Marinho, KS; Dos Santos, KRP; Gomes Melo, ME; Lapa Neto, CJC; Teixeira, VW, 2019)
"Melatonin was analyzed in 392 breast milk samples from 98 healthy nursing mothers at 0 to 30 days postpartum."1.51Variations in melatonin levels in preterm and term human breast milk during the first month after delivery. ( Bei, F; Bu, J; Liu, Y; Qin, Y; Shi, W; Sun, J; Tang, L; Zhuang, J, 2019)
"Melatonin has protective roles in normal cells and cytotoxic actions in cancer cells, with effects involving autophagy and nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor pathways."1.51Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells. ( Bienvenue-Pariseault, J; Sagrillo-Fagundes, L; Vaillancourt, C, 2019)
"Melatonin has been shown to reduce oxidative stress and mitigate hypercoagulability."1.51Melatonin for prevention of placental malperfusion and fetal compromise associated with intrauterine inflammation-induced oxidative stress in a mouse model. ( Burd, I; Dong, J; Jia, B; Jones-Beatty, K; Lee, JY; Lei, J; Li, S; McLane, MW; Na, Q; Ozen, M; Shin, NE, 2019)
"Melatonin acts as an antioxidant and prevents oxidative stress-induced changes in cytotrophoblasts."1.48Melatonin Improves Mitochondrial Respiration in Syncytiotrophoblasts From Placentas of Obese Women. ( Ireland, KE; Maloyan, A; Myatt, L, 2018)
"Melatonin (Mel) has strong antioxidant properties since it is a direct scavenger of oxygen-based free radicals and related species."1.48The neuroprotective effect of melatonin on the hippocampus exposed to diclofenac sodium during the prenatal period. ( Kaplan, S; Kıvrak, EG; Yurt, KK, 2018)
"Low melatonin levels are a frequent finding in ASD patients."1.48Low maternal melatonin level increases autism spectrum disorder risk in children. ( Braam, W; Curfs, L; Ehrhart, F; Maas, APHM; Smits, MG, 2018)
"Melatonin, which is an antioxidant and neuroprotective agent, can be an effective treatment for neurological disorders."1.48Therapeutic effect of perinatal exogenous melatonin on behavioral and histopathological changes and antioxidative enzymes in neonate mouse model of cortical malformation. ( Azizi, M; Kashani, IR; Mokhtari, T; Nadji, SA; Omidi, N; Pasbakhsh, P; Pourabdollah, M; Sadr, M; Zendehdel, A, 2018)
" We examined whether maternal melatonin therapy can prevent maternal high-fructose combined with post-weaning high-salt diet-induced programmed hypertension in adult offspring."1.48Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring. ( Chan, JYH; Lee, WC; Leu, S; Tain, YL; Wu, KLH, 2018)
"Melatonin did not increase HO-1 expression in any of the tissues examined."1.48Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia. ( Beard, S; Binder, NK; Hannan, NJ; Kaitu'u-Lino, TJ; Nguyen, TV; Tong, S, 2018)
"Children are more susceptible to Giardia lamblia infection."1.48Human colostrum action against Giardia lamblia infection influenced by hormones and advanced maternal age. ( Fagundes, DLG; Fernandes, RTS; França, EL; França-Botelho, ADC; Gomes, MA; Hara, CCP; Honorio-França, AC; Pereira, QLC, 2018)
"Melatonin is a powerful antioxidant that can act as a protective agent against DNA damage caused by genotoxic agents, such as ethanol."1.48Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy. ( Chagas, CA; Lapa Neto, CJC; Santos, KRPD; Silva, MAD; Sousa Coelho, IDD; Souza, TGDS; Teixeira, ÁAC; Wanderley Teixeira, V, 2018)
"Melatonin is a free radical scavenger, anti-oxidant and anti-apoptotic agent that reported to enhance the quality of embryos by inhibiting ROS generation and apoptosis."1.48Melatonin supplementation during prolonged in vitro maturation improves the quality and development of poor-quality porcine oocytes via anti-oxidative and anti-apoptotic effects. ( Cho, ES; Il Jin, D; Kang, JW; Kim, SB; Lee, JE; Lin, T; Oqani, RK, 2018)
"Preterm birth is a major contributor to early and delayed physical and cognitive impairment."1.46Maternal administration of melatonin exerts short- and long-term neuroprotective effects on the offspring from lipopolysaccharide-treated mice. ( Aisemberg, J; Bariani, MV; Correa, F; Domínguez Rubio, AP; Dorfman, D; Franchi, AM; Rosenstein, RE; Zorrilla Zubilete, M, 2017)
"The exact cause of preeclampsia is unknown."1.46Melatonin prevents preeclamptic sera and antiphospholipid antibodies inducing the production of reactive nitrogen species and extrusion of toxic trophoblastic debris from first trimester placentae. ( Chamley, LW; Chen, Q; Groom, K; Hickey, A; Li, Y; Stone, PR; Xu, L; Zhao, M, 2017)
"Melatonin plays crucial roles in a wide range of ovarian physiological functions via the melatonin receptors (MRs)."1.46Molecular characterization and expression profile of the melatonin receptor MT1 in the ovary of Tianzhu white yak (Bos grunniens). ( Hu, JJ; Li, FD; Tao, JZ; Zhang, XY; Zhang, Y; Zhao, XX, 2017)
"Melatonin treatment could improve memory deficits, antioxidants activity and reduced MDA levels in the hippocampus."1.46Maternal administration of melatonin prevents spatial learning and memory deficits induced by developmental ethanol and lead co-exposure. ( Abrari, K; Goudarzi, I; Lashkarbolouki, T; Soleimani, E, 2017)
"Melatonin treatment of the chick embryo starting at day 13 of incubation, equivalent to ca."1.43Melatonin rescues cardiovascular dysfunction during hypoxic development in the chick embryo. ( Beck, C; Giussani, DA; Itani, N; Niu, Y; Skeffington, KL, 2016)
"Melatonin treatment did not show a protective effect on neuronal metabolism."1.43No improvement of neuronal metabolism in the reperfusion phase with melatonin treatment after hypoxic-ischemic brain injury in the neonatal rat. ( Berger, HR; Brubakk, AM; Morken, TS; Sonnewald, U; Vettukattil, R; Widerøe, M, 2016)
"Melatonin was administered in drinking water (0."1.43Postnatal dexamethasone-induced programmed hypertension is related to the regulation of melatonin and its receptors. ( Chang, HY; Tain, YL, 2016)
"Serum was collected from women with preeclampsia (n=113) and gestation-matched healthy pregnant women, and the levels of melatonin were measured."1.43The reduction in circulating levels of melatonin may be associated with the development of preeclampsia. ( Chen, Q; Gao, Y; Lee, AC; Tong, M; Wan, J; Zeng, K; Zhao, M, 2016)
"Melatonin has been used as a supplement in culture medium to improve the efficiency of in vitro produced mammalian embryos."1.43Effects of Two Types of Melatonin-Loaded Nanocapsules with Distinct Supramolecular Structures: Polymeric (NC) and Lipid-Core Nanocapsules (LNC) on Bovine Embryo Culture Model. ( Basso, AC; Beck, RC; Bordignon, V; Campos, VF; Collares, T; Deschamps, JC; Domingues, WB; Guterres, SS; Jornada, DS; Komninou, ER; Lucas, CG; Pohlmann, AR; Remião, MH; Seixas, FK, 2016)
"Melatonin (5 mg/kg) was administered i."1.43Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway. ( Albertini, MC; Balduini, W; Buonocore, G; Carloni, S; Chalon, S; Favrais, G; Gressens, P; Longini, M; Saliba, E, 2016)
"Melatonin has been suggested as a treatment for preeclampsia and intrauterine growth restriction because of its protective antioxidant effects."1.43Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption. ( Bienvenue-Pariseault, J; Clabault, H; Fortier, M; Hudon-Thibeault, AA; Laurent, L; Sagrillo-Fagundes, L; Salustiano, EM; Sanderson, JT; Vaillancourt, C; Wong Yen, P, 2016)
"Oxidative stress is present in pregnancy complications."1.43Maternal plasma antioxidant status in the first trimester of pregnancy and development of obstetric complications. ( Aguilera, Y; Arribas, SM; Condezo-Hoyos, L; De La Calle, M; Gómez-Rioja, R; González, MC; Gutiérrez-Arzapalo, PY; Herrera, T; López De Pablo, ÁL; López-Giménez, MR; Martín-Cabrejas, MA; Montero, P; Mora-Urda, AI; Moreno-Jiménez, B; Ramiro-Cortijo, D; Rodríguez-Rodríguez, P, 2016)
"Melatonin has been reported to serve as an indirect antioxidant via the stimulation and induction of antioxidant enzymes as superoxide dismutase (SOD) and glutathione peroxidase (Gpx) in several tissues."1.42Antioxidative status and oxidative stress in the fetal circulation at birth: the effects of time of delivery and presence of labor. ( Bagci, S; Bartmann, P; Katzer, D; Mueller, A; Reinsberg, J; Reutter, H; Welzing, L, 2015)
"Melatonin was administered from PND21 to the rats exposed to dexamethasone, and the outcome was assessed at ∼PND120."1.42Effects of melatonin on prenatal dexamethasone-induced epigenetic alterations in hippocampal morphology and reelin and glutamic acid decarboxylase 67 levels. ( Chang, KA; Chen, CC; Hsu, MH; Huang, LT; Kuo, HC; Lui, CC; Sheen, JM; Tain, YL; Tiao, MM; Yu, HR, 2015)
"Melatonin has various physiological functions, including circadian rhythm regulation, free-radical scavenging, and gonadal development."1.42Melatonin inhibits embryonic salivary gland branching morphogenesis by regulating both epithelial cell adhesion and morphology. ( Hattori, A; Maruyama, Y; Miura, J; Nakamura, W; Nohara, K; Obana-Koshino, A; Ono, H; Sakai, M; Sakai, T; Uchida, H, 2015)
"Melatonin (10mg/kg) was given once daily at the same time."1.42Melatonin ameliorates oxidative damage induced by maternal lead exposure in rat pups. ( Bazrgar, M; Elahdadi Salmani, M; Goudarzi, I; Lashkarbolouki, T, 2015)
"Melatonin is a naturally occurring indolamine with mild antioxidant properties that is neuroprotective in perinatal animals."1.40Partial neural protection with prophylactic low-dose melatonin after asphyxia in preterm fetal sheep. ( Bennet, L; Booth, LC; Davidson, JO; Drury, PP; Fraser, M; Gunn, AJ; Tan, S; van den Heuij, LG, 2014)
"For this purpose, preterm labor was induced in BALB/c mice by intraperitoneal injections of bacterial lipopolysaccharide (LPS) at 10."1.40Melatonin prevents experimental preterm labor and increases offspring survival. ( Aisemberg, J; Bariani, MV; Cella, M; Domínguez Rubio, AP; Franchi, AM; Rosenstein, RE; Salazar, AI; Sordelli, MS, 2014)
"Melatonin treatment significantly reduced LPS-induced neurobehavioral disturbances and brain damage in neonatal rats."1.40Melatonin ameliorates brain injury induced by systemic lipopolysaccharide in neonatal rats. ( Fan, LW; Jow, GM; Kaizaki, A; Tien, LT; Wong, CS, 2014)
" In isolated neonatal coronary arteries, endothelium-dependent nitric oxide (NO) bioavailability was reduced in IUGR, and was rescued by modest melatonin treatment."1.40Maternal melatonin administration mitigates coronary stiffness and endothelial dysfunction, and improves heart resilience to insult in growth restricted lambs. ( Coleman, HA; Jenkin, G; Lim, R; Miller, SL; Parkington, HC; Sutherland, AE; Tare, M; Wallace, EM; Yawno, T, 2014)
"Melatonin was reported to prevent hypertension development."1.40Melatonin prevents maternal fructose intake-induced programmed hypertension in the offspring: roles of nitric oxide and arachidonic acid metabolites. ( Chan, JY; Lee, WC; Leu, S; Tain, YL; Wu, KL, 2014)
"Melatonin plays pivotal role in biological circadian rhythms."1.40Melatonin secretion is impaired in women with preeclampsia and an abnormal circadian blood pressure rhythm. ( Arampatzis, S; Bouchlariotou, S; Eleftheriadis, T; Giannopoulou, M; Liakopoulos, V; Mertens, PR; Messinis, IE; Stefanidis, I; Zintzaras, E, 2014)
"Melatonin concentration was higher in colostrum samples from hyperglycemic than normoglycemic mothers."1.39Antioxidant effect of melatonin on the functional activity of colostral phagocytes in diabetic women. ( Calderon, IM; Fagundes, DL; França, EL; Honorio-França, AC; Morceli, G, 2013)
"Placentas were classified into gestational hypertension (GH), chronic hypertension (CH), pre-eclampsia (PE) and pre-eclampsia superimposed on chronic hypertension, and morphologically examined by hematoxylin-eosin and periodic acid Schiff methods."1.39Increase of placental sensitivity to melatonin and the alteration to its local synthesis in hypertensive syndromes in pregnancy. ( Corrêa, RR; Guimarães, CS; Machado, JR; Reis, MA; Rocha, LP; Yamamoto, Dde R; Yamamoto, Lde R, 2013)
"This melatonin-induced increase in umbilical artery blood flow may alter nutrient availability to the fetus, which may lead to alterations in fetal size."1.39Dietary melatonin supplementation alters uteroplacental amino acid flux during intrauterine growth restriction in ewes. ( Camacho, LE; Caton, JS; Kapphahn, M; Lemley, CO; Meyer, AM; Vonnahme, KA, 2013)
"Melatonin receptors have been described throughout the cardiovascular system; however, there is a paucity of data on the function of placental melatonin receptors."1.39Uterine infusion of melatonin or melatonin receptor antagonist alters ovine feto-placental hemodynamics during midgestation. ( Camacho, LE; Lemley, CO; Vonnahme, KA, 2013)
"Melatonin has diverse physiological actions in addition to its well-recognized maintenance roles in circadian and seasonal timing."1.38Mechanisms of melatonin-induced protection in the brain of late gestation fetal sheep in response to hypoxia. ( Castillo-Melendez, M; Jenkin, G; Miller, SL; Walker, DW; Wallace, EM; Yawno, T, 2012)
"Melatonin is a potent deprogrammer of neonatal corticosterone programming effects and the adult thrifty phenotype alteration to a diabetogenic challenge."1.38Neonatal corticosterone programs for thrifty phenotype adult diabetic manifestations and oxidative stress: countering effect of melatonin as a deprogrammer. ( Baxi, DB; Ramachandran, AV; Singh, PK; Vachhrajani, KD, 2012)
"Melatonin is a potent antioxidant known to reverse free-radical mediated injury in the brain."1.37Neuroprotection by melatonin after germinal matrix hemorrhage in neonatal rats. ( Hartman, R; Lekic, T; Manaenko, A; Rolland, W; Tang, J; Virbel, K; Zhang, JH, 2011)
"Food intake and weight gain are known to be affected by stress."1.36The weight gain response to stress during adulthood is conditioned by both sex and prenatal stress exposure. ( Argente, J; Azcoitia, I; Calmarza-Font, I; Chowen, JA; Diz-Chaves, Y; Frago, LM; García-Cáceres, C; Garcia-Segura, LM; Lagunas, N, 2010)
"It has been concluded that cortical dysplasia induced by intrauterine BCNU administration results in delayed hippocampal maturation, which is successfully restored by intrauterine melatonin treatment."1.36Investigation of maternal melatonin effect on the hippocampal formation of newborn rat model of intrauterine cortical dysplasia. ( Ateş, U; Baka, M; Kültürsay, N; Uyanikgil, Y, 2010)
"Melatonin treatment significantly improved the number of fertilized embryos/corpus luteum (CL) (-MEL: 0."1.36Effects of exogenous melatonin on in vivo embryo viability and oocyte competence of undernourished ewes after weaning during the seasonal anestrus. ( Abecia, JA; Casao, A; Forcada, F; Vázquez, MI, 2010)
"Melatonin-treated animals had a higher rate of pregnancy (P < 0."1.36Effect of genotype at the MTNR1A locus and melatonin treatment on first conception in Sarda ewe lambs. ( Bini, PP; Carcangiu, V; Luridiana, S; Mura, MC; Vacca, GM, 2010)
"We tested the hypothesis that treatment during pregnancy with melatonin increases umbilical blood flow via NO-dependent mechanisms."1.36Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms. ( Giussani, DA; Herrera, EA; Serón-Ferré, M; Thakor, AS, 2010)
"When melatonin treatment was used, however, the responses of flocks on individual farms were difficult to predict because within a year, responses did not occur on all farms."1.35Effects of annual rainfall and farm on lamb production after treatment with melatonin implants in Merino sheep: a 4-year study. ( Abecia, JA; Arrebola, FA; Forcada, F; Garcia, A; Martín, RA; Mesa, O, 2009)
"Melatonin also acts as a potent endogenous antioxidant by scavenging free radicals and upregulating antioxidant pathways."1.35Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy. ( Giussani, DA; Hansell, JA; Raut, S; Richter, HG, 2009)
"Melatonin (MT) has profound neurotrophic and neuroprotective effects."1.35Melatonin regulates the viability and differentiation of rat midbrain neural stem cells. ( Cai, Z; Kong, X; Li, X; Liu, Y; Pan, L; Shu, J; Yang, N; Zuo, P, 2008)
"Treatment with melatonin during pregnancy improved learning deficits and prevented the reduction of glial and neuronal markers induced by hyperhomocysteinemia."1.35Melatonin prevents gestational hyperhomocysteinemia-associated alterations in neurobehavioral developments in rats. ( Baydas, G; Koz, ST; Nedzvetsky, VS; Tuzcu, M, 2008)
"Melatonin treatment did not affect any parameter but FGA advanced the kidding date."1.34Highly synchronous and fertile reproductive activity induced by the male effect during deep anoestrus in lactating goats subjected to treatment with artificially long days followed by a natural photoperiod. ( Bernelas, D; Bonné, JL; Chemineau, P; Forgerit, Y; Leboeuf, B; Pellicer-Rubio, MT; Pougnard, JL; Senty, E, 2007)
"Melatonin treatment resulted in a slower recovery of fetal blood pressure following umbilical cord occlusion, but without changes in fetal heart rate, acid base status or mortality."1.34Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion. ( Gressens, P; Hagberg, H; Kjellmer, I; Lapatto, R; Mallard, C; Sultan, B; Svedin, P; Welin, AK, 2007)
"Melatonin pretreatment significantly attenuated LPS-evoked elevation of TNF-alpha in maternal serum."1.34Maternally administered melatonin differentially regulates lipopolysaccharide-induced proinflammatory and anti-inflammatory cytokines in maternal serum, amniotic fluid, fetal liver, and fetal brain. ( Chen, YH; Ning, H; Wang, H; Xu, DX; Zhao, L, 2007)
"Melatonin plays a critical role in a variety of mammalian reproductive processes not only acting on the central nervous system but also behaving as a peripheral physiologic regulator."1.33Melatonin as a local regulator of human placental function. ( Iwasaki, S; Iwashita, M; Kometani, K; Maruyama, T; Nakazawa, K; Sakai, J; Yoshimura, Y, 2005)
"Melatonin is a powerful endogenous antioxidant."1.33Melatonin protects against lipopolysaccharide-induced intra-uterine fetal death and growth retardation in mice. ( Chen, YH; Sun, MF; Wang, H; Wang, JP; Wei, LZ; Wei, W; Xu, DX, 2006)
"This melatonin effect was strong in PX rats but relatively weak in SX rats."1.33Physiological pineal effects on female reproductive function of laboratory rats: prenatal development of pups, litter size and estrous cycle in middle age. ( Fujieda, H; Kachi, T; Suzuki, R; Tanaka, D; Tonosaki, Y; Watanabe, S, 2006)
"When melatonin was given to the mothers instead of the endogenous pineal secretory activity for 5 days during the late period of gestation, this treatment reversed the effects of maternal ganglionectomy and pinealectomy."1.33Pup circadian rhythm entrainment--effect of maternal ganglionectomy or pinealectomy. ( Bellavía, SL; Carpentieri, AR; Macchione, AF; Vaqué, AM; Vermouth, NT, 2006)
"This melatonin treatment induces gonadal regression in photosensitive but not in photorefractory hamsters."1.32Termination of neuroendocrine refractoriness to melatonin in Siberian hamsters (Phodopus sungorus). ( Freeman, DA; Kauffman, AS; Zucker, I, 2003)
"Oral melatonin treatment (30 mg per day for 30 days) prior to eCG/hCG administration only marginally reduced ancillary follicle development and had no significant effect on the quantity or quality of embryos produced by AI."1.32Influence of oral melatonin on natural and gonadotropin-induced ovarian function in the domestic cat. ( Brown, JL; Graham, LH; Swanson, WF; Wildt, DE, 2004)
"Melatonin treatment reversed ischemia/reperfusion-induced reduction in RCI (2."1.32Maternally administered melatonin protects against ischemia and reperfusion-induced oxidative mitochondrial damage in premature fetal rat brain. ( Fukaya, T; Ikenoue, N; Shinohara, K; Wakatsuki, A; Watanabe, K; Yokota, K, 2004)
"Melatonin receptors were found to be localized in the estrous rat uterine antimesometrial stroma."1.31Variations of mt1 melatonin receptor density in the rat uterus during decidualization, the estrous cycle and in response to exogenous steroid treatment. ( Pang, SF; Poon, AM; Zhao, H, 2002)
"Melatonin is a powerful scavenger of oxygen free radicals."1.31Melatonin increases activities of glutathione peroxidase and superoxide dismutase in fetal rat brain. ( Kaneda, C; Okatani, Y; Wakatsuki, A, 2000)
"Pretreatment with melatonin significantly increased NO2 production that had been decreased by H2O2 in a concentration-dependent manner (P<0."1.31Melatonin protects against the free radical-induced impairment of nitric oxide production in the human umbilical artery. ( Okatani, Y; Wakatsuki, A, 2000)
"Pretreatment with mannitol significantly suppressed the vasospastic effect of LPC."1.31Melatonin suppresses lysophosphatidylcholine enhancement of serotonin-induced vasoconstriction in the human umbilical artery. ( Fukaya, T; Okatani, Y; Taniguchi, K; Wakatsuki, A; Watanabe, K, 2000)
"Pretreatment with melatonin significantly increased the activity of GSH-Px (20."1.31Melatonin protects fetal rat brain against oxidative mitochondrial damage. ( Fukaya, T; Ikenoue, N; Kaneda, C; Okatani, Y; Shinohara, K; Wakatsuki, A, 2001)
"Melatonin (6 mg) was administered orally at 12:00 hr, and samples of chorion and maternal blood were obtained at the time of the procedure, 1, 2 or 3 hr later."1.31Melatonin stimulates glutathione peroxidase activity in human chorion. ( Fukaya, T; Kaneda, C; Okatani, Y; Shinohara, K; Wakatsuki, A, 2001)
"Melatonin treatment reversed the ischemia/reperfusion-induced reductions in the RCI (2."1.31Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain. ( Fukaya, T; Ikenoue, N; Okatani, Y; Shinohara, K; Wakatsuki, A, 2001)
"Melatonin could be useful in treating preeclampsia and possibly other clinical states involving excess free radical production, such as fetal growth restriction and fetal hypoxia."1.31Melatonin protects against oxidative mitochondrial damage induced in rat placenta by ischemia and reperfusion. ( Fukaya, T; Okatani, Y; Shinohara, K; Taniguchi, K; Wakatsuki, A, 2001)
"Pre-treatment with melatonin significantly increased NO(2)(-) production that had been decreased by oxidized LDL (P<0."1.31Melatonin protects against oxidized low-density lipoprotein-induced inhibition of nitric oxide production in human umbilical artery. ( Fukaya, T; Ikenoue, N; Okatani, Y; Shinohara, K; Wakatsuki, A; Watanabe, K, 2001)
"Propranolol did not cause any change in E2 secretion, and when given with Me, it only partially blocked but could not entirely prevent E2 output."1.31Influence of melatonin on basal and gonadotropin-stimulated progesterone and estradiol secretion of cultured human granulosa cells and in the superfused granulosa cell system. ( Bódis, J; Koppán, M; Kornya, L; Tinneberg, HR; Török, A, 2001)
"Melatonin levels were lower for selected ewes (143 +/- 14 pg/mL) than for control ewes (184 +/- 13 pg/mL), and melatonin levels decreased with increases in estimated breeding values (EBV) for fertility (-2."1.31Nocturnal melatonin and prolactin plasma concentrations in sheep selected for fertility in autumn lambing'. ( Chemineau, P; Notter, DR, 2001)
"Treatment with melatonin prior to exposure to H2O2 significantly restored the relaxation induced by A23187 (P < 0."1.30Melatonin inhibits vasospastic action of hydrogen peroxide in human umbilical artery. ( Hayashi, K; Okatani, Y; Sagara, Y; Wakatsuki, A; Watanabe, K, 1997)
"Melatonin pretreatment significantly suppressed the contractile response to external calcium."1.30Melatonin suppresses vasospastic effect of hydrogen peroxide in human umbilical artery: relation to calcium influx. ( Hayashi, K; Okatani, Y; Sagara, Y; Wakatsuki, A; Watanabe, K, 1997)
"Melatonin treatment increased O2 consumption in mice injected with saline but suppressed the increased metabolic rate associated with an immune response in KLH-injected animals."1.30Metabolic costs of mounting an antigen-stimulated immune response in adult and aged C57BL/6J mice. ( Chefer, V; Demas, GE; Nelson, RJ; Talan, MI, 1997)
" The values (mean +/- SD) for the cows and the goats were: elimination half-life 27 +/- 4 min and 27 +/- 1 min, mean residence time 24 +/- 4 min and 18 +/- 4 min, steady state distribution volume 1."1.30Diurnal rhythm of melatonin in bovine milk: pharmacokinetics of exogenous melatonin in lactating cows and goats. ( Eriksson, L; Kaikkonen, M; Laitinen, JT; Paananen, M; Valtonen, M, 1998)
"Melatonin (MEL) is a widely used, over-the-counter sleep aid, and it has putative contraceptive, antioxidant, antiaging, and anticancer effects."1.30Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats. ( Jahnke, G; Marr, M; Myers, C; Price, C; Travlos, G; Wilson, R, 1999)
"Summer infertility is thought to be influenced by heat, sunburn and stress."1.30Physical mapping of porcine seasonality genes. ( Anderson, SI; Archibald, AL; Lopez-Corrales, NL; Skinner, TM; Yerle, M, 1999)
"Melatonin concentration was measured in plasma samples obtained at 4-hourly intervals in a 24 h period and < 200 lux for all subjects studied."1.29Sex steroids do not alter melatonin secretion in the human. ( Baars, S; Delfs, TM; Fock, C; Olcese, J; Schumacher, M; Zimmermann, RC, 1994)
"Melatonin treatment failed to alter pulse frequency after the initial increase."1.28Effect of melatonin on pulsatile release of luteinizing hormone in female lambs. ( Argo, CM; Rajkumar, RR; Rodway, RG, 1992)
"Colic is periodic behavior occurring at the end of the day during the first 3 months of life characterized by crying."1.28Colic, sleep inertia, melatonin and circannual rhythms. ( Weissbluth, L; Weissbluth, M, 1992)
"Melatonin has been postulated to act as a prostaglandin (PG) synthetase inhibitor in the uterus."1.28Lack of effect of melatonin on myometrial electromyographic activity in the pregnant sheep at 138-142 days gestation (term = 147 days gestation). ( Mitchell, MD; Nathanielsz, PW; Sadowsky, DW; Yellon, S, 1991)
"Melatonin was detectable in neonates (5-day-old), but day vs night differences in indole constituents did not occur until 10 days of age."1.28Pineal gland free amino acids and indoles during postnatal development of the rat: correlations in individual glands. ( Bowman, DC; McNulty, JA; McReynolds, HD, 1990)
"This melatonin effect was also shared by its biologically active analogues 5-methoxytryptophol and 6-chloromelatonin."1.27Melatonin inhibits beta-adrenoceptor-stimulated cyclic AMP accumulation in rat astroglial cell cultures. ( Berría, MI; Cardinali, DP; Lascano, EF; Vacas, MI, 1984)
"Melatonin-treated bucks exhibited a marked advancement of neck muscle hypertrophy during the treatment period and displayed normal rutting activity (e."1.27Effects of subcutaneous melatonin implants on reproductive seasonality of farmed fallow deer (Dama dama). ( Adam, JL; Asher, GW; Barrell, GK; Staples, LD, 1988)
"125I-melatonin promises to be a useful tool for understanding the sites and mechanism of action of melatonin."1.27Iodinated melatonin mimics melatonin action and reveals discrete binding sites in fetal brain. ( Namboodiri, MA; Reppert, SM; Weaver, DR, 1988)
" No clear dose-response relationship was noticed over the range of electric field strengths used as treatments in these experiments."1.27Reduction of the nocturnal rise in pineal melatonin levels in rats exposed to 60-Hz electric fields in utero and for 23 days after birth. ( Anderson, LE; Buschbom, RL; Reiter, RJ; Wilson, BW, 1988)
"Melatonin implants were placed in 5 adult female possums during December."1.27Effect of melatonin and removal of pouch young on the seasonality of births in the marsupial possum, Trichosurus vulpecula. ( Gemmell, RT, 1987)
"Melatonin treatment increased the basal concentration of LH (Groups CC + EC = 0."1.27Induction and persistence of pituitary and ovarian activity in the out-of-season lactating dairy goat after a treatment combining a skeleton photoperiod, melatonin and the male effect. ( Chemineau, P; Normant, E; Ravault, JP; Thimonier, J, 1986)
"Melatonin was administered from 12 June 1984 (day 1) to lactating and non-lactating hinds in the feed daily at 1600 h, and to non-lactating hinds by a subcutaneous implant."1.27Melatonin lowers plasma prolactin levels in female red deer (Cervus elaphus). ( Adam, CL; Atkinson, T; Moir, CE, 1987)
"Of 5 melatonin-treated tammars, 4 gave birth on Day 45, so had failed to respond to the melatonin injection alone but reactivated when this was combined with the endogenous melatonin rise during exposure to 15L:9D."1.27Change in duration of elevated concentrations of melatonin is the major factor in photoperiod response of the tammar, Macropus eugenii. ( Hinds, LA; McConnell, SJ; Tyndale-Biscoe, CH, 1986)
"Melatonin-treated hinds lost slightly more live weight than did controls from June to November, but their suckled calves grew throughout at a rate similar to those of control hinds."1.27Induction of early breeding in red deer (Cervus elaphus) by melatonin. ( Adam, CL; Atkinson, T; Moir, CE, 1986)
"Melatonin was measured by radioimmunoassay according to Brun et al."1.27Diurnal variations of plasma melatonin concentrations in pregnant or pseudopregnant mink (Mustela vison) maintained under different photoperiods. ( Bonnefond, C; Brun, J; Claustrat, B; Martinet, L; Ravault, JP, 1986)
"melatonin treatments for 70 days led to atrophy of the testes and accessory sex organs and to a significant depression of both plasma LH and PRL titers."1.26Influence of morning melatonin injections on the antigonadotrophic effects of afternoon melatonin administration in male and female hamsters. ( Brainard, GC; de la Santos, R; Huerter, JJ; Reiter, RJ; Richardson, BA; Vaughan, MK, 1981)
"When melatonin synthesis was delayed by extending the photophase on proestrus, serum LH levels were significantly elevated at 2200h."1.26Melatonin:serotonin interaction during termination of the LH surge in rats. ( Walker, RF, 1982)
"Melatonin was detected in the circulation of the near-term rhesus monkey (Macaca mulatta) and baboon (Papio papio) fetus."1.26Maternal-fetal transfer of melatonin in the non-human primate. ( Anderson, A; Chez, RA; Klein, DC; Reppert, SM, 1979)
" Daily administration of the same dosage of melatonin at 2400 and 0100 h failed to interrupt estrous cyclicity or reduce testis weight."1.26Effect of melatonin administered during the night on reproductive function in the Syrian hamster. ( Goldman, BD; Hollister, CW; Lefebvre, NG; Tamarkin, L, 1977)
"[3H]Melatonin was found to be rapidly transferred from the maternal circulation into lactating mammary tissue, and the stomach of each suckling rat was found to contain [3H]melatonin."1.26Transport of maternal[3H]melatonin to suckling rats and the fate of [3H]melatonin in the neonatal rat. ( Klein, DC; Reppert, SM, 1978)

Research

Studies (769)

TimeframeStudies, this research(%)All Research%
pre-1990161 (20.94)18.7374
1990's102 (13.26)18.2507
2000's129 (16.78)29.6817
2010's241 (31.34)24.3611
2020's136 (17.69)2.80

Authors

AuthorsStudies
Charif, SE1
Inserra, PIF1
Schmidt, AR1
Cortasa, SA1
Proietto, S1
Corso, MC1
Halperin, J1
Di Giorgio, NP1
Lux-Lantos, V1
Vitullo, AD1
Dorfman, VB1
Mejlhede, MAB1
Jepsen, JB1
Knudsen, UB1
Su, G1
Wu, S3
Wu, M1
Wang, L6
Yang, L2
Du, M2
Zhao, X5
Su, X1
Liu, X7
Bai, C1
Wei, Z1
Cheng, L1
Li, G2
Hansell, JA2
Richter, HG6
Camm, EJ1
Herrera, EA6
Blanco, CE1
Villamor, E1
Patey, OV1
Lock, MC1
Trafford, AW1
Galli, GLJ1
Giussani, DA5
Favrais, G2
Saliba, E2
Savary, L1
Bodard, S1
Gulhan, Z1
Gressens, P3
Chalon, S2
Zhang, WL1
Zhang, ZL1
Peng, J2
Yang, ST1
Chen, JX1
Wang, CX1
Tong, DW1
Zhang, W1
Zhang, Z2
Yang, S3
Tong, D1
Çalışkan, C3
Çelik, S4
Hatirnaz, S1
Çelik, H1
Avcı, B1
Tinelli, A1
de Melo, IMF2
Ferreira, CGM2
Alves, ÉR1
D'Assunção, CG1
Neto, CJCL1
de Albuquerque, YML3
Wanderley Teixeira, V3
Teixeira, ÁAC5
Suarez-Trujillo, A2
Hoang, N1
Robinson, L1
McCabe, CJ1
Conklin, D1
Minor, RC1
Townsend, J1
Plaut, K2
George, UZ1
Boerman, J1
Casey, TM2
Slyepchenko, A1
Minuzzi, L1
Reilly, JP1
Frey, BN1
Al-Kuraishi, AH1
Khalil, HI1
Hasan, HH1
Al-Kuraishy, HM1
Liu, Z2
Chen, B1
Chang, J1
Feng, L3
Candia, AA1
Arias, PV1
González-Candia, C1
Navarrete, A1
Ebensperger, G3
Reyes, RV3
Llanos, AJ5
González-Candia, A3
Li, H4
Liu, M3
Zhang, C5
Jantzie, LL1
Muthukumar, S1
Kitase, Y1
Vasan, V1
Fouda, MA1
Hamimi, S1
Burkhardt, C1
Burton, VJ1
Gerner, G1
Scafidi, J1
Ye, X2
Northington, FJ1
Robinson, S1
Zhang, H2
Zheng, Y1
Zha, X1
Elsabagh, M1
Zhang, Y11
Ma, Y1
Loor, JJ1
Wang, M2
Wang, H10
Ding, JJ1
Jiao, C1
Qi, YL1
Guo, HX1
Yuan, QQ1
Huang, YN1
Han, JQ1
Ma, XY1
Xu, J1
Tavakoli, M1
Moghadamnia, AA1
Pourabdolhossein, F1
Asghari, MH1
Kazemi, S1
Tang, S2
Jiang, Y2
Long, F1
He, F1
Liu, J5
Gu, S1
Lu, Y2
Yin, Z1
Bao, Z1
Wang, R1
Xue, S1
Zeng, Y1
Deng, S3
Zhou, C1
Ding, Y3
Yu, L1
Nie, Y1
Yang, M3
Fantasia, I1
Bussolaro, S1
Stampalija, T1
Rolnik, DL1
Tchekalarova, J2
Kortenska, L1
Marinov, P1
Ivanova, N2
Feng, X5
Li, N4
Zheng, Q1
Sun, M2
Tang, J2
Xu, Z1
Lucignani, G1
Jannello, LMI1
Fulgheri, I1
Silvani, C1
Turetti, M1
Gadda, F1
Viganò, P1
Somigliana, E1
Montanari, E1
Boeri, L1
Contreras-Correa, ZE4
Cochran, T1
Metcalfe, A1
Burnett, DD4
Lemley, CO17
Cui, Y3
Xiang, G3
Yu, M3
Wang, X4
Qiu, B3
Li, XG3
Liu, W5
Zhang, D4
Li, XL3
Zhu, HJ3
Zhang, Q5
Li, YS3
Li, YC3
Yuan, RY3
Sha, QQ4
Ma, JY3
Luo, SM3
Sun, QY4
Chen, LN3
Ou, XH4
Harman, AR2
Messman, RD4
Swanson, RM2
Ajackson, M2
Nagagata, BA2
Marcondes-de-Castro, IA2
Mandarim-de-Lacerda, CA2
Aguila, MB2
Dzirbíková, Z2
Stebelová, K2
Kováčová, K2
Okuliarová, M2
Olexová, L2
Zeman, M3
Bagci, S6
Wieduwilt, A2
Alsat, EA2
Blickwedel, J2
Strizek, B2
Di Battista, C2
Lachner, A1
Plischke, H2
Melaku, T2
Müller, A4
Parry, BL8
Meliska, CJ7
Sorenson, DL6
Martinez, LF6
Lopez, AM6
Dawes, SE1
Elliott, JA2
Hauger, RL3
Wei, L1
Gao, P1
Zhang, J4
Zhou, X2
Zhu, S1
Chen, Y5
DU, Y2
Fang, C1
Li, J3
Gao, X4
He, M1
Wang, S5
Yu, J1
Atanasova, M1
Nenchovska, Z1
Diallo, AB1
Coiffard, B1
Desbriere, R1
Katsogiannou, M1
Donato, X1
Bretelle, F1
Mezouar, S1
Mege, JL1
Pereira, GDAV1
Morais, TC2
França, EL5
Daboin, BEG1
Bezerra, IMP1
Pessoa, RS1
de Quental, OB1
Honório-França, AC5
Abreu, LC1
Pluta, R1
Furmaga-Jabłońska, W1
Januszewski, S1
Tarkowska, A1
Chen, XQ1
Jiang, XM1
Zheng, QX1
Wang, HW1
Xue, H1
Pan, YQ1
Liao, YP1
Gao, XX1
Reid, DS1
Geary, TW1
Zezeski, AL1
Waterman, RC1
Van Emon, ML1
Hashem, NM1
El-Hawy, AS1
El-Bassiony, MF1
Saber, A1
Radwan, MA1
Ghanem, N1
Leyva-Corona, JC1
Angulo-Valenzuela, NI1
Laborin-Escalante, BM1
Gastelum-Delgado, MA1
Silva-Avila, NJ1
Luna-Nevárez, P1
Aragón-López, CE1
Sánchez-Castro, MA1
Morales-Pablos, MI1
Ma, X1
Wang, J10
Yan, L1
Liu, Y6
Ma, W1
Ji, P2
Zhang, L4
Liu, G5
Bagheri, F2
Goudarzi, I4
França, DCH2
Sobrevia, L2
Barbosa, AMP1
Rudge, MVC1
Peng, Z1
Xin, WZ1
Sheng, ZY1
Zi, T1
Nan, LY1
Lin, WZ1
Jun, LF1
Xia, LX1
Savka, RF1
Mykolaiovych Berbets, A1
Mykhailovych Barbe, A1
Mykhailovych Yuzko, O1
Radu, MR1
Jin, S2
Wang, TT1
Huang, JC1
Wang, YS1
Guo, B1
Yue, ZP1
Albzea, W1
Almonayea, L1
Aljassar, M1
Atmeh, M1
Al Sadder, K1
AlQattan, Y1
Alhajaji, R1
AlNadwi, H1
Alnami, I1
Alhajaji, F1
Teoh, AN2
Kaur, S2
Shafie, SR2
Shukri, NHM2
Bustami, NA2
Takahashi, M2
Shibata, S2
Wang, XJ1
Li, XT1
Chen, N1
Huang, L2
Huang, SX1
Chen, TT1
Liu, GH1
Hu, RF1
Rubinstein, MR1
Burgueño, AL1
Quiroga, S1
Wald, MR1
Genaro, AM1
Calsa, B1
de Camargo, LS1
Bortolança, TJ1
de Oliveira, CA1
Catisti, R1
do Amaral, FG2
Santamaria-Jr, M1
Qu, J1
Hu, H1
Niu, H1
Sun, X2
Li, Y9
Pačesová, D1
Spišská, V1
Novotný, J1
Bendová, Z1
Silva, KMR1
de Queiroz, AA1
Fagundes-Triches, DLG1
de Marchi, PGF1
Lapa Neto, CJC3
Alpiovezza, PKBM1
Francisco Soares, A1
Wanderley-Teixeira, V3
Méndez, N6
Corvalan, F1
Halabi, D2
Ehrenfeld, P1
Maldonado, R1
Vergara, K2
Seron-Ferre, M16
Torres-Farfan, C12
Gáspárdy, A1
Gallagher, G1
Bartha, B1
Cseh, S1
Fekete, SG1
Somoskői, B1
Tüfekci, KK1
Kaplan, AA1
Kaya, A1
Alrafiah, A1
Altun, G2
Aktaş, A1
Kaplan, S5
Albertini, MC2
Vanzolini, T1
Perrone, S2
Weiss, MD1
Buonocore, G5
Dell'Orto, V1
Balduini, W5
Carloni, S5
Li, A1
Li, F1
Song, W1
Lei, ZL1
Liu, SY1
Zhou, CY1
Zhang, X3
Li, XZ2
Schatten, H1
Zhang, T3
Peng, X1
Zhong, H1
Liu, S2
Shi, J2
Li, B3
Abid, F1
Ahmed, S1
Noushad, S1
Farhat, S1
Fatima, SS1
Nehme, PA1
Amaral, F1
Lowden, A1
Skene, DJ1
Cipolla-Neto, J7
Moreno, CRC2
Latif Khan, H1
Bhatti, S1
Latif Khan, Y1
Abbas, S1
Munir, Z1
Rahman Khan Sherwani, IA1
Suhail, S1
Hassan, Z1
Aydin, HH1
Minguini, IP1
Luquetti, CM1
Baracat, MCP1
Maganhin, CC1
Nunes, CO1
Simões, RS2
Veiga, ECA1
Cipolla Neto, J2
Baracat, EC2
Soares Junior, JM1
Avilés, R1
Delgadillo, JA3
Flores, JA2
Duarte, G1
Vielma, J1
Flores, MJ1
Petrovski, K1
Zarazaga, LA5
Hernández, H2
Arend, LS1
Knox, RV1
Greiner, LL1
Graham, AB1
Connor, JF1
Maes, M1
Anderson, G4
Betancort Medina, SR1
Seo, M1
Ojala, JO1
do Nascimento Marinho, KS1
de Sousa Coelho, IDD1
da Silva, MA1
Gomes Melo, ME1
Dos Santos, KRP1
Chagas, CA2
Coelho Teixeira, ÁA1
Teixeira, VW1
Hsu, CN6
Huang, LT8
Tain, YL14
Qin, Y1
Shi, W1
Zhuang, J1
Tang, L2
Bu, J1
Sun, J2
Bei, F1
Chuffa, LGA1
Lupi, LA1
Cucielo, MS1
Silveira, HS1
Reiter, RJ30
Seiva, FRF1
Wernert, G1
Sun, H1
Steckler, TS1
Huff, K1
Cummings, S1
Franco, J1
Klopp, RN1
Townsend, JR1
Grott, M1
Johnson, JS1
Boerman, JP1
Pipová Kokošová, N1
Kisková, T1
Vilhanová, K1
Štafuriková, A1
Jendželovský, R1
Račeková, E1
Šmajda, B1
Qu, P1
Shen, C1
Qin, H1
Luo, S1
Fu, S1
Dong, Y2
Guo, S1
Hu, F1
Xue, Y1
Liu, E1
Lim, PJ1
Swarnamani, K1
Davies-Tuck, M1
Wallace, E2
Mol, BW1
Mockler, J1
Bai, J1
Zhao, Z2
Wang, B2
Obeysekare, JL1
Cohen, ZL1
Coles, ME1
Pearlstein, TB2
Monzon, C1
Flynn, EE1
Sharkey, KM2
D Assunção, CG1
Baptista, MGP1
Alves, RDC1
Abdelnaby, EA2
Zussman, R1
Xu, LY1
Damani, T1
Groom, KM2
Chen, Q5
Seers, B1
Viall, CA1
Chamley, LW2
Hickey, A2
Abecia, JA8
Garrido, C1
Gave, M1
García, AI1
López, D1
Luis, S1
Valares, JA1
Mata, L1
Hu, KL1
Liu, WX1
Tan, SJ1
Wang, YF2
Li, L4
Sun, XF2
Klinger, FG1
De Felici, M1
Shen, W1
Cheng, SF1
Bae, H1
Yang, C1
Lee, JY6
Park, S1
Bazer, FW1
Song, G1
Lim, W1
Zuo, J1
Jiang, Z3
Sabir, H1
Wang, D1
Wu, X1
Lu, D1
Zhang, P1
Na, Q2
Shin, NE3
Shin, HE1
Kang, Y1
Chudnovets, A1
Lei, J3
Song, H2
Burd, I3
Lachner, AB1
Herzog, ED1
Doğanlar, O2
Doğanlar, ZB2
Ovali, MA2
Güçlü, O1
Demir, U2
Doğan, A2
Uzun, M3
El-Mokadem, MY2
Nour El-Din, ANM1
Ramadan, TA3
Taha, TA2
Samak, MA2
Sharaby, MA1
Rashad, AM1
Nese, M1
Riboli, G1
Brighetti, G1
Sassi, V1
Camela, E1
Caselli, G1
Sassaroli, S1
Borlimi, R1
Aucoin, M1
Cooley, K1
Saunders, PR1
Carè, J1
Anheyer, D1
Medina, DN1
Cardozo, V1
Remy, D1
Hannan, N1
Garber, A1
Velayos, M1
Muñoz-Serrano, AJ1
Estefanía-Fernández, K1
Sarmiento Caldas, MC1
Moratilla Lapeña, L1
López-Santamaría, M1
López-Gutiérrez, JC1
Shen, S1
Zhang, B2
Yu, WW1
Toyoda, H1
Huang, DQ1
Le, MH1
Nguyen, MH1
Huang, R1
Zhu, L1
Xue, L1
Liu, L3
Yan, X2
Huang, S1
Xu, T1
Li, C2
Ji, F1
Ming, F1
Zhao, Y2
Cheng, J1
Wang, Y5
Zhao, H2
Hong, S1
Chen, K2
Zhao, XA1
Zou, L1
Sang, D1
Shao, H1
Guan, X1
Chen, X4
Wei, J1
Zhu, C1
Wu, C1
Moore, HB1
Barrett, CD1
Moore, EE1
Jhunjhunwala, R1
McIntyre, RC1
Moore, PK1
Hajizadeh, N1
Talmor, DS1
Sauaia, A1
Yaffe, MB1
Liu, C3
Lin, Y1
Wu, Y2
Bao, Y1
Yan, H2
Ma, J1
Fernández-Cuadros, ME1
Albaladejo-Florín, MJ1
Álava-Rabasa, S1
Usandizaga-Elio, I1
Martinez-Quintanilla Jimenez, D1
Peña-Lora, D1
Neira-Borrajo, I1
López-Muñoz, MJ1
Rodríguez-de-Cía, J1
Pérez-Moro, OS1
Abdallah, M1
Alsaleh, H1
Baradwan, A1
Alfawares, R1
Alobaid, A1
Rasheed, A1
Soliman, I1
Wendel Garcia, PD1
Fumeaux, T1
Guerci, P1
Heuberger, DM1
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Clinical Trials (20)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Melatonin as Neuroprotectant in Preterm Infants .A Prospective, Double Blind vs Placebo, Parallel Arms Study[NCT04235673]60 participants (Actual)Interventional2020-05-25Completed
Prognostic Value of Serum Melatonin as a Biomarker for the Determination of Severe COVID-19 Infection in Pregnant Women[NCT05318144]228 participants (Actual)Observational [Patient Registry]2021-06-01Completed
The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression[NCT02769858]10 participants (Actual)Interventional2015-06-30Completed
COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation (COOL-COS) Associated With Corifollitropin Alfa: a Pilot Study[NCT02448459]Phase 140 participants (Actual)Interventional2015-05-31Completed
Evaluation of a Simplified Low-cost and Friendly Controlled Ovarian Stimulation Combining Oral Letrozole and Clomiphene Citrate: a Pilot Study[NCT02288143]Phase 428 participants (Actual)Interventional2015-01-31Completed
A Pilot Study of Maternally Administered Melatonin to Decrease the Level of Oxidative Stress in Human Pregnancies Affected by Intrauterine Growth Restriction.[NCT01695070]Phase 416 participants (Actual)Interventional2012-09-30Completed
Nightly Suppression of Contractions in At-Risk Pregnancies by the Infusion of Defused Blue Light[NCT03691740]30 participants (Anticipated)Interventional2018-09-06Recruiting
Comparison of IVF Outcome and Endometrium Effect in Infertility Patients Between Diminished and Normal Ovarian Reserve After Melatonin Administration.[NCT03117725]100 participants (Anticipated)Interventional2017-05-12Enrolling by invitation
Umbilical Cord and Maternal Blood Concentrations of Melatonin, Soluble Urokinase-type Plasminogen Activator Receptor, and Orosomucoid 2 in Pregnancy Complicated by Preterm Premature Rupture of the Membranes and Histological Chorioamnionitis[NCT04588220]88 participants (Anticipated)Observational2020-10-07Active, not recruiting
The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment[NCT05298657]200 participants (Anticipated)Observational [Patient Registry]2022-09-01Not yet recruiting
Feasibility and Efficacy of an Internet-delivered Cognitive-behavioral Intervention for Insomnia in a National Cohort of Danish Breast Cancer Survivors[NCT02444026]225 participants (Anticipated)Interventional2014-12-31Recruiting
Improving Oocyte Retrieval Using a Combined Therapy of Recombinant Follicle Stimulating Hormone (rFSH) and Inositol and Melatonin[NCT01267604]Phase 40 participants (Actual)Interventional2010-12-31Withdrawn
Effects of Myo-inositol Plus Melatonin in Perimenopausal Women[NCT01325389]0 participants InterventionalRecruiting
A Prospective, Randomized, Double Blind, Study on the Clinical Efficacy Myo-inositol Versus D-chiro-inositol in Women Undergoing in Vitro Fertilization Embryo Transfer.[NCT01338844]Phase 40 participants InterventionalCompleted
Myo-inositol for the Management of Poor Ovarian Responders: A Prospective Randomized Controlled Trial[NCT04273256]Phase 2/Phase 3226 participants (Anticipated)Interventional2020-02-11Recruiting
Sleep Length and Euploid Embryo Transfer Prospective Study[NCT06139757]150 participants (Anticipated)Observational2024-01-01Not yet recruiting
Use of Melatonin for Neuroprotection in Term Infants With Hypoxic-ischaemic Encephalopathy[NCT03806816]100 participants (Anticipated)Interventional2018-12-13Recruiting
Melatonin for Neuroprotection Following Perinatal Asphyxia[NCT02071160]Phase 1/Phase 245 participants (Actual)Interventional2012-01-31Completed
A Randomised, Double-blind, Placebo-controlled Study of Light Therapy for Antepartum Depression[NCT01043289]46 participants (Actual)Interventional2004-10-31Completed
A Pilot, Open-label Study to Evaluate the Effects of a Prostate Health Formulation on Scores Attained From the International Prostate Symptom Score (I-PSS) Questionnaire Among Overall Healthy Male Participants Who Report Lower Urinary Tract Complaints[NCT02886832]30 participants (Anticipated)Interventional2016-09-21Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline Time of Dim Light Melatonin Onset (DLMO) at 5 Weeks

Onset of melatonin in dim light conditions as measured in saliva (also called DLMO) Time of DLMO is measured in clock time, so a positive number in change would represent a later onset of melatonin and a negative number represents an earlier onset of melatonin (NCT02769858)
Timeframe: After five weeks of light therapy

Interventionminutes (Mean)
Light Therapy-6

Change From Baseline Score of the Edinburgh Postnatal Depression Scale (EPDS) at 5 Weeks

Self-report of depression symptoms. The Edinburgh Postnatal Depression scale is scored from 0 to 30 where 0 is no depression and 30 is most severe depression. (NCT02769858)
Timeframe: After five weeks of light therapy

InterventionEPDS score (Mean)
Pre-Treatment (EPDSPost-Treatment (EPDS)
Light Therapy12.757.75

Change From Baseline Score of the Hamilton Depression Rating Scale-Seasonal Affective Version (SIGH-SAD) at 5 Weeks

Clinician-rated depression symptom severity measure; Hamilton Depression Rating Scale-Seasonal Affective Version (SIGH-SAD) (29 item version) measures depressive symptoms on a continuous scale. Higher scores indicate worse outcomes. Scores can range from 0 -73, where 0 means no depression, and 73 is the greatest possible depression. Generally scores of 20 or higher represent clinical depression (NCT02769858)
Timeframe: After five weeks of light therapy

InterventionSIGH-SAD score (Mean)
Pre-treatmentPost-treatment
Light Therapy24.7512.88

Reviews

126 reviews available for melatonin and Pregnancy

ArticleYear
Oral melatonin supplementation during
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2021, Volume: 37, Issue:12

    Topics: Administration, Oral; Antioxidants; Dietary Supplements; Female; Fertilization in Vitro; Humans; Mel

2021
The role of melatonin in pregnancies complicated by placental insufficiency: A systematic review.
    European journal of obstetrics, gynecology, and reproductive biology, 2022, Volume: 278

    Topics: Antioxidants; Aspirin; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Melatonin; Placent

2022
Melatonin in Reproductive Medicine: A Promising Therapeutic Target?
    Current medicinal chemistry, 2023, Volume: 30, Issue:27

    Topics: Antioxidants; Circadian Rhythm; Female; Humans; Melatonin; Pineal Gland; Pregnancy; Reproduction; Re

2023
Coenzyme Q10 and Melatonin for the Treatment of Male Infertility: A Narrative Review.
    Nutrients, 2022, Nov-01, Volume: 14, Issue:21

    Topics: Antioxidants; Female; Humans; Infertility, Male; Male; Melatonin; Oxidative Stress; Pregnancy; Semen

2022
Melatonin: A Potential Candidate for the Treatment of Experimental and Clinical Perinatal Asphyxia.
    Molecules (Basel, Switzerland), 2023, Jan-22, Volume: 28, Issue:3

    Topics: Animals; Asphyxia; Asphyxia Neonatorum; Brain Injuries; Female; Humans; Hypothermia; Hypoxia-Ischemi

2023
Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with gestational diabetes mellitus.
    Biochimica et biophysica acta. Molecular basis of disease, 2023, Volume: 1869, Issue:6

    Topics: Cytokines; Diabetes, Gestational; Female; Humans; Hyperglycemia; Melatonin; Nutrigenomics; Pregnancy

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Efficacy and Safety of Preoperative Melatonin for Women Undergoing Cesarean Section: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.
    Medicina (Kaunas, Lithuania), 2023, Jun-01, Volume: 59, Issue:6

    Topics: Analgesics; Anxiety; Cesarean Section; Female; Humans; Melatonin; Pain, Postoperative; Pregnancy; Ra

2023
Current Understanding of the Roles of Gut-Brain Axis in the Cognitive Deficits Caused by Perinatal Stress Exposure.
    Cells, 2023, Jun-28, Volume: 12, Issue:13

    Topics: Brain-Gut Axis; Cognition; Cognitive Dysfunction; Female; Gastrointestinal Microbiome; Humans; Infan

2023
From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin.
    Journal of pineal research, 2023, Volume: 75, Issue:4

    Topics: Adult; Circadian Rhythm; Female; Humans; Melatonin; Noncommunicable Diseases; Photoperiod; Pregnancy

2023
Melatonin effects on ovarian follicular cells: a systematic review.
    Revista da Associacao Medica Brasileira (1992), 2019, Sep-12, Volume: 65, Issue:8

    Topics: Cells, Cultured; Female; Granulosa Cells; Humans; Melatonin; Oocytes; Ovarian Follicle; Pregnancy; P

2019
Integrating Autism Spectrum Disorder Pathophysiology: Mitochondria, Vitamin A, CD38, Oxytocin, Serotonin and Melatonergic Alterations in the Placenta and Gut.
    Current pharmaceutical design, 2019, Volume: 25, Issue:41

    Topics: ADP-ribosyl Cyclase 1; Autism Spectrum Disorder; Female; Humans; Melatonin; Mitochondria; Oxytocin;

2019
Perinatal Use of Melatonin for Offspring Health: Focus on Cardiovascular and Neurological Diseases.
    International journal of molecular sciences, 2019, Nov-13, Volume: 20, Issue:22

    Topics: Animals; Antioxidants; Cardiovascular Diseases; Female; Fetal Development; Fetal Diseases; Humans; I

2019
Melatonin Promotes Uterine and Placental Health: Potential Molecular Mechanisms.
    International journal of molecular sciences, 2019, Dec-31, Volume: 21, Issue:1

    Topics: Abortion, Habitual; Circadian Rhythm; Endometriosis; Endometrium; Female; Humans; Melatonin; Menstru

2019
Light and Circadian Signaling Pathway in Pregnancy: Programming of Adult Health and Disease.
    International journal of molecular sciences, 2020, Mar-23, Volume: 21, Issue:6

    Topics: Animals; Circadian Clocks; Circadian Rhythm; Disease Susceptibility; Embryonic Development; Female;

2020
Melatonin Application in Assisted Reproductive Technology: A Systematic Review and Meta-Analysis of Randomized Trials.
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Adolescent; Adult; Female; Humans; Infant, Newborn; Infertility; Live Birth; Male; Melatonin; Pregna

2020
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Maternal pineal melatonin in gestation and lactation physiology, and in fetal development and programming.
    General and comparative endocrinology, 2021, 01-01, Volume: 300

    Topics: Animals; Female; Fetal Development; Humans; Lactation; Mammary Glands, Human; Melatonin; Nervous Sys

2021
Melatonin Administration from 2000 to 2020 to Human Newborns with Hypoxic-Ischemic Encephalopathy.
    American journal of perinatology, 2022, Volume: 39, Issue:8

    Topics: Asphyxia; Asphyxia Neonatorum; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant

2022
Relationship between melatonin and high-risk pregnancy: A review of investigations published between the years 2010 and 2020.
    Chronobiology international, 2021, Volume: 38, Issue:2

    Topics: Antioxidants; Circadian Rhythm; Female; Humans; Melatonin; Polymorphism, Genetic; Pregnancy; Pregnan

2021
Perinatal hypoxic-ischemic damage: review of the current treatment possibilities.
    Physiological research, 2020, 12-31, Volume: 69, Issue:Suppl 3

    Topics: Central Nervous System Depressants; Erythropoietin; Female; Humans; Hypoxia; Hypoxia-Ischemia, Brain

2020
Melatonin for the prevention of fetal injury associated with intrauterine inflammation.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2021, Volume: 86, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; Bronchopulmonary Dysplasia; Female; Fetal Disease

2021
Maternal Melatonin Deficiency Leads to Endocrine Pathologies in Children in Early Ontogenesis.
    International journal of molecular sciences, 2021, Feb-19, Volume: 22, Issue:4

    Topics: Child; Circadian Rhythm; Endocrine System; Female; Fetal Development; Fetus; Humans; Melatonin; Meta

2021
The Crosstalk between Melatonin and Sex Steroid Hormones.
    Neuroendocrinology, 2022, Volume: 112, Issue:2

    Topics: Animals; Female; Gonadal Steroid Hormones; Gonads; Humans; Male; Melatonin; Menopause; Placenta; Pre

2022
Maternal effects in mammals: Broadening our understanding of offspring programming.
    Frontiers in neuroendocrinology, 2021, Volume: 62

    Topics: Animals; Female; Mammals; Maternal Inheritance; Melatonin; Photoperiod; Pregnancy

2021
Melatonin, Its Beneficial Effects on Embryogenesis from Mitigating Oxidative Stress to Regulating Gene Expression.
    International journal of molecular sciences, 2021, May-30, Volume: 22, Issue:11

    Topics: Animals; Embryo Implantation; Embryo, Mammalian; Embryonic Development; Female; Gene Expression Regu

2021
Melatonin and Myo-Inositol: Supporting Reproduction from the Oocyte to Birth.
    International journal of molecular sciences, 2021, Aug-05, Volume: 22, Issue:16

    Topics: Animals; Female; Fertilization; Humans; Inositol; Melatonin; Oocytes; Parturition; Pregnancy; Pregna

2021
The regulations and role of circadian clock and melatonin in uterine receptivity and pregnancy-An immunological perspective.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2017, Volume: 78, Issue:2

    Topics: Animals; Circadian Clocks; Female; Humans; Melatonin; Pregnancy; Pregnancy Complications; Uterus

2017
PHYSIOLOGY AND ENDOCRINOLOGY SYMPOSIUM: Alterations in uteroplacental hemodynamics during melatonin supplementation in sheep and cattle.
    Journal of animal science, 2017, Volume: 95, Issue:5

    Topics: Animals; Antioxidants; Cattle; Diet; Dietary Supplements; Endocrinology; Female; Fetal Development;

2017
The Relationship between Autism Spectrum Disorder and Melatonin during Fetal Development.
    Molecules (Basel, Switzerland), 2018, Jan-18, Volume: 23, Issue:1

    Topics: Animals; Autism Spectrum Disorder; Circadian Rhythm; Female; Fetal Development; Humans; Maternal Exp

2018
The case for a chronobiological approach to neonatal care.
    Early human development, 2018, Volume: 126

    Topics: Animals; Chronobiology Discipline; Circadian Rhythm; Feeding Behavior; Female; Humans; Infant Formul

2018
From Implantation to Birth: Insight into Molecular Melatonin Functions.
    International journal of molecular sciences, 2018, Sep-17, Volume: 19, Issue:9

    Topics: Animals; Antioxidants; Embryo Implantation; Female; Fetal Development; Humans; Melatonin; Oocytes; P

2018
Melatonin treatment in fetal and neonatal diseases.
    Pathology, research and practice, 2018, Volume: 214, Issue:12

    Topics: Animals; Antioxidants; Female; Fetal Diseases; Humans; Melatonin; Oxidative Stress; Placenta; Pregna

2018
Inositol for subfertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Abortion, Spontaneous; Administration, Oral; Birth Rate; Clomiphene; Combined Modality Therapy; Fema

2018
Maternal photoperiodic programming enlightens the internal regulation of thyroid-hormone deiodinases in tanycytes.
    Journal of neuroendocrinology, 2019, Volume: 31, Issue:1

    Topics: Animals; Ependymoglial Cells; Female; Hypothalamus; Iodide Peroxidase; Maternal-Fetal Exchange; Mela

2019
Oxidative stress: Normal pregnancy versus preeclampsia.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 02-01, Volume: 1866, Issue:2

    Topics: Animals; Antioxidants; Endothelial Cells; Female; Free Radicals; Humans; Ischemia; Melatonin; Oxidat

2020
The reduction of melatonin levels is associated with the development of preeclampsia: a meta-analysis.
    Hypertension in pregnancy, 2019, Volume: 38, Issue:2

    Topics: Female; Humans; Melatonin; Pre-Eclampsia; Pregnancy

2019
Neuroprotective strategies following perinatal hypoxia-ischemia: Taking aim at NOS.
    Free radical biology & medicine, 2019, Volume: 142

    Topics: Allopurinol; Asphyxia Neonatorum; Biotin; Cerebral Palsy; Clinical Trials as Topic; Epilepsy; Erythr

2019
Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care.
    Cell death & disease, 2019, 04-08, Volume: 10, Issue:4

    Topics: Autophagy; Blood-Brain Barrier; Cell Death; Female; Free Radical Scavengers; Humans; Infant, Newborn

2019
Novel interventions to reduce oxidative-stress related brain injury in neonatal asphyxia.
    Free radical biology & medicine, 2019, Volume: 142

    Topics: Acetylcysteine; Allopurinol; Argon; Asphyxia Neonatorum; Cannabinoids; Erythropoietin; Female; Human

2019
The usefulness of melatonin in the field of obstetrics and gynecology.
    Pharmacological research, 2019, Volume: 147

    Topics: Animals; Antioxidants; Biomarkers; Dietary Supplements; Female; Gynecology; Humans; Melatonin; Obste

2019
Melatonin and female reproduction.
    The journal of obstetrics and gynaecology research, 2014, Volume: 40, Issue:1

    Topics: Animals; Circadian Rhythm; Female; Genitalia, Female; Humans; Melatonin; Menopause; Oogenesis; Ovula

2014
Melatonin supplementation during controlled ovarian stimulation for women undergoing assisted reproductive technology: systematic review and meta-analysis of randomized controlled trials.
    Fertility and sterility, 2014, Volume: 101, Issue:1

    Topics: Dietary Supplements; Female; Humans; Melatonin; Ovulation Induction; Pregnancy; Pregnancy Rate; Rand

2014
Melatonin supplementation during controlled ovarian stimulation for women undergoing assisted reproductive technology: systematic review and meta-analysis of randomized controlled trials.
    Fertility and sterility, 2014, Volume: 101, Issue:1

    Topics: Dietary Supplements; Female; Humans; Melatonin; Ovulation Induction; Pregnancy; Pregnancy Rate; Rand

2014
Melatonin supplementation during controlled ovarian stimulation for women undergoing assisted reproductive technology: systematic review and meta-analysis of randomized controlled trials.
    Fertility and sterility, 2014, Volume: 101, Issue:1

    Topics: Dietary Supplements; Female; Humans; Melatonin; Ovulation Induction; Pregnancy; Pregnancy Rate; Rand

2014
Melatonin supplementation during controlled ovarian stimulation for women undergoing assisted reproductive technology: systematic review and meta-analysis of randomized controlled trials.
    Fertility and sterility, 2014, Volume: 101, Issue:1

    Topics: Dietary Supplements; Female; Humans; Melatonin; Ovulation Induction; Pregnancy; Pregnancy Rate; Rand

2014
Clinical relevance of melatonin in ovarian and placental physiology: a review.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:2

    Topics: Female; Humans; Melatonin; Ovary; Oxidative Stress; Placenta; Pregnancy; Reactive Oxygen Species

2014
Maternal and placental melatonin: actions and implication for successful pregnancies.
    Minerva ginecologica, 2014, Volume: 66, Issue:3

    Topics: Animals; Antioxidants; Biomarkers; Female; Humans; Melatonin; Oxidative Stress; Placenta; Pre-Eclamp

2014
Melatonin and the circadian system: contributions to successful female reproduction.
    Fertility and sterility, 2014, Volume: 102, Issue:2

    Topics: Animals; Chronobiology Disorders; Circadian Clocks; Circadian Rhythm; Female; Fetus; Humans; Light;

2014
Clinical significance of melatonin receptors in the human myometrium.
    Fertility and sterility, 2014, Volume: 102, Issue:2

    Topics: Circadian Clocks; Circadian Rhythm; Female; Humans; Light; Melatonin; Myometrium; Oxytocin; Photoper

2014
Transcriptional regulation of programmed hypertension by melatonin: an epigenetic perspective.
    International journal of molecular sciences, 2014, Oct-14, Volume: 15, Issue:10

    Topics: Animals; Epigenesis, Genetic; Female; Gene Expression Regulation; Humans; Hypertension; Kidney; Mela

2014
Melatonin: a "Higgs boson" in human reproduction.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:2

    Topics: Circadian Rhythm; Embryonic Development; Female; Humans; Male; Melatonin; Ovarian Follicle; Pineal G

2015
Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2016, Volume: 29, Issue:4

    Topics: Adult; Antioxidants; Brain; Cerebral Palsy; Child; Cognition Disorders; Depression; Developmental Di

2016
[Oxidative stress after preterm birth: origins, biomarkers, and possible therapeutic approaches].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2015, Volume: 22, Issue:10

    Topics: Advanced Oxidation Protein Products; Aldehydes; Antioxidants; Biomarkers; Breast Feeding; Delivery R

2015
Potential Utility of Melatonin in Preeclampsia, Intrauterine Fetal Growth Retardation, and Perinatal Asphyxia.
    Reproductive sciences (Thousand Oaks, Calif.), 2016, Volume: 23, Issue:8

    Topics: Animals; Antioxidants; Asphyxia Neonatorum; Female; Fetal Growth Retardation; Humans; Infant, Newbor

2016
Melatonin in Pregnancy: Effects on Brain Development and CNS Programming Disorders.
    Current pharmaceutical design, 2016, Volume: 22, Issue:8

    Topics: Antioxidants; Brain; Central Nervous System Diseases; Female; Fetus; Humans; Melatonin; Neuroprotect

2016
The Effects of Electromagnetic Field on the Endocrine System in Children and Adolescents.
    Pediatric endocrinology reviews : PER, 2015, Volume: 13, Issue:2

    Topics: Adolescent; Adrenal Glands; Adult; Animals; Cell Phone; Child; Electromagnetic Fields; Endocrine Sys

2015
Melatonin for women in pregnancy for neuroprotection of the fetus.
    The Cochrane database of systematic reviews, 2016, Mar-29, Volume: 3

    Topics: Female; Fetus; Humans; Melatonin; Neuroprotection; Neuroprotective Agents; Pregnancy

2016
Potential benefits of melatonin in organ transplantation: a review.
    The Journal of endocrinology, 2016, Volume: 229, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Female; Graft Rejection; Humans; Male; Melatonin; O

2016
Ventilation-Induced Brain Injury in Preterm Neonates: A Review of Potential Therapies.
    Neonatology, 2016, Volume: 110, Issue:2

    Topics: Brain Injuries; Delivery Rooms; Erythropoietin; Female; Glucocorticoids; Humans; Infant, Newborn; In

2016
Developmental Programming of Adult Disease: Reprogramming by Melatonin?
    International journal of molecular sciences, 2017, Feb-16, Volume: 18, Issue:2

    Topics: Adult; Animals; Disease Susceptibility; Female; Fetal Development; Humans; Melatonin; Models, Animal

2017
Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin.
    Journal of pineal research, 2009, Volume: 46, Issue:2

    Topics: Animals; Asphyxia Neonatorum; Clinical Trials as Topic; Female; Free Radical Scavengers; Humans; Inf

2009
Melatonin and reproduction revisited.
    Biology of reproduction, 2009, Volume: 81, Issue:3

    Topics: Animals; Female; Humans; Marriage; Melatonin; Models, Biological; Oxidative Stress; Pineal Gland; Pr

2009
Melatonin and human reproduction: shedding light on the darkness hormone.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2009, Volume: 25, Issue:12

    Topics: Circadian Rhythm; Female; Humans; Male; Melatonin; Ovary; Pineal Gland; Pregnancy; Reproduction; Tes

2009
Pharmaceutical control of reproduction in sheep and goats.
    The Veterinary clinics of North America. Food animal practice, 2011, Volume: 27, Issue:1

    Topics: Animals; Estrous Cycle; Female; Goats; Male; Melatonin; Pregnancy; Progesterone; Reproduction; Seaso

2011
Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:3

    Topics: Adult; Antioxidants; Female; Humans; Infant, Newborn; Melatonin; Oxidative Stress; Perinatal Care; P

2012
Contribution of myo-inositol and melatonin to human reproduction.
    European journal of obstetrics, gynecology, and reproductive biology, 2011, Volume: 159, Issue:2

    Topics: Diet; Dietary Supplements; Embryonic Development; Female; Humans; Inositol; Inositol Phosphates; Mal

2011
Circadian rhythms in the fetus.
    Molecular and cellular endocrinology, 2012, Feb-05, Volume: 349, Issue:1

    Topics: Adrenal Glands; Animals; Circadian Rhythm; Female; Fetus; Humans; Maternal-Fetal Exchange; Melatonin

2012
Melatonin utility in neonates and children.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2012, Volume: 111, Issue:2

    Topics: Antioxidants; Child; Female; Fetal Growth Retardation; Humans; Hypoxia-Ischemia, Brain; Infant, Newb

2012
A rhythmic placenta? Circadian variation, clock genes and placental function.
    Placenta, 2012, Volume: 33, Issue:7

    Topics: Animals; Body Temperature Regulation; Circadian Clocks; Circadian Rhythm; Circadian Rhythm Signaling

2012
Melatonin and the circadian timing of human parturition.
    Reproductive sciences (Thousand Oaks, Calif.), 2013, Volume: 20, Issue:2

    Topics: Animals; Circadian Rhythm; Female; Humans; Infant, Newborn; Labor, Obstetric; Melatonin; Parturition

2013
The fetal origins of the metabolic syndrome: can we intervene?
    Journal of pregnancy, 2012, Volume: 2012

    Topics: Antioxidants; Ascorbic Acid; Diet Therapy; Dietary Supplements; Exenatide; Fatty Acids, Omega-3; Fem

2012
Programming of the fetal suprachiasmatic nucleus and subsequent adult rhythmicity.
    Trends in endocrinology and metabolism: TEM, 2002, Volume: 13, Issue:9

    Topics: Animals; Birth Weight; Body Height; Circadian Rhythm; Drug-Related Side Effects and Adverse Reaction

2002
Photoperiodic effects on endocrine and immune function in cattle.
    Reproduction (Cambridge, England). Supplement, 2002, Volume: 59

    Topics: Animals; Cattle; Endocrine System; Female; Immune System; Insulin-Like Growth Factor I; Lactation; M

2002
Pattern of melatonin secretion mediates transfer of photoperiod information from mother to fetus in mammals.
    Science's STKE : signal transduction knowledge environment, 2003, Jul-22, Volume: 2003, Issue:192

    Topics: Animals; Biological Clocks; Embryonic and Fetal Development; Female; Mammals; Maternal-Fetal Exchang

2003
Sleep, rhythms and women's mood. Part I. Menstrual cycle, pregnancy and postpartum.
    Sleep medicine reviews, 2006, Volume: 10, Issue:2

    Topics: Affect; Body Temperature; Female; Humans; Hydrocortisone; Melatonin; Menstrual Cycle; Postpartum Per

2006
Cutaneous sarcoidosis therapy updated.
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:1

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents

2007
Haemozoin: from melatonin pigment to drug target, diagnostic tool, and immune modulator.
    The Lancet. Infectious diseases, 2007, Volume: 7, Issue:10

    Topics: Animals; Antimalarials; Crystallization; Erythrocytes; Female; Hemeproteins; Humans; Leukocytes; Mal

2007
Circadian clocks during embryonic and fetal development.
    Birth defects research. Part C, Embryo today : reviews, 2007, Volume: 81, Issue:3

    Topics: Animals; Biological Clocks; Circadian Rhythm; Embryo, Mammalian; Female; Fetus; Gene Expression Regu

2007
Neuroendocrine-immune interactions in synovitis.
    Nature clinical practice. Rheumatology, 2007, Volume: 3, Issue:11

    Topics: Arthritis, Rheumatoid; Female; Gonadal Steroid Hormones; Humans; Hypothalamo-Hypophyseal System; Mal

2007
Melatonin and human chronobiology.
    Cold Spring Harbor symposia on quantitative biology, 2007, Volume: 72

    Topics: Blindness; Chronobiology Phenomena; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Huma

2007
Melatonin and pregnancy in the human.
    Reproductive toxicology (Elmsford, N.Y.), 2008, Volume: 25, Issue:3

    Topics: Abortion, Spontaneous; Circadian Rhythm; Female; Fetal Development; Fetal Hypoxia; Humans; Maternal-

2008
Circadian rhythms, brain peptides, and reproduction.
    Advances in biochemical psychopharmacology, 1981, Volume: 28

    Topics: Animals; Brain Chemistry; Circadian Rhythm; Estrus; Female; Hormones; Male; Melatonin; Neurotransmit

1981
The pineal and its hormones in the control of reproduction in mammals.
    Endocrine reviews, 1980,Spring, Volume: 1, Issue:2

    Topics: Acetyltransferases; Adaptation, Physiological; Animals; Atrophy; Circadian Rhythm; Estrus; Female; F

1980
The melatonin rhythm generating system: developmental aspects.
    Life sciences, 1981, May-04, Volume: 28, Issue:18

    Topics: Acetylserotonin O-Methyltransferase; Animals; Aromatic-L-Amino-Acid Decarboxylases; Arylamine N-Acet

1981
[Problems and prospects of vitiligo study].
    Vestnik dermatologii i venerologii, 1981, Issue:10

    Topics: Adrenal Cortex; Animals; Autoimmune Diseases; Biogenic Amines; Cyclic AMP; Female; Humans; Melanins;

1981
Circadian rhythms of pineal function in rats.
    Endocrine reviews, 1983,Summer, Volume: 4, Issue:3

    Topics: Acetyltransferases; Aging; Animals; Bucladesine; Circadian Rhythm; Cyclic AMP; Darkness; Female; Lig

1983
Neuroendocrine basis of seasonal reproduction.
    Recent progress in hormone research, 1984, Volume: 40

    Topics: Animals; Blindness; Castration; Estradiol; Estrus; Feedback; Female; Gonadotropin-Releasing Hormone;

1984
Seasonal breeding: nature's contraceptive.
    Recent progress in hormone research, 1980, Volume: 36

    Topics: Animals; Breeding; Castration; Circadian Rhythm; Deer; Estrus; Female; Follicle Stimulating Hormone;

1980
Hormonal regulation of the annual reproductive cycle of golden hamsters.
    General and comparative endocrinology, 1981, Volume: 45, Issue:3

    Topics: Animals; Castration; Cricetinae; Estrus; Female; Follicle Stimulating Hormone; Hormones; Luteinizing

1981
The psychoneuroendocrinology of the ovulatory cycle of woman: a review.
    Psychoneuroendocrinology, 1980, Volume: 5, Issue:2

    Topics: Animals; Biogenic Amines; Corpus Luteum; Endometrium; Estrogens; Feedback; Female; Fertility; Gonado

1980
Transport of protein-bound hormones into tissues in vivo.
    Endocrine reviews, 1981,Winter, Volume: 2, Issue:1

    Topics: Aldosterone; Animals; Biological Transport, Active; Blood-Brain Barrier; Capillary Permeability; Car

1981
[Role of the hypothalamus in the regulation of luteinizing hormone secretion and in the ovulation process].
    Acta physiologica Polonica, 1981, Volume: 32 Suppl 23

    Topics: Animals; Catecholamines; Estrus; Female; Gonadotropin-Releasing Hormone; Hormones; Hypothalamus; Lut

1981
Seasonal effects on fertility in gilts and sows.
    Journal of reproduction and fertility. Supplement, 1993, Volume: 48

    Topics: Animals; Diet; Female; Fertility; Luteinizing Hormone; Male; Melatonin; Photoperiod; Pregnancy; Seas

1993
[Role of melatonin in human physiology and pathology. I. Circadian rhythm of melatonin secretion. Involvement of melatonin in reproductive physiology. Melatonin and hypothalamic-pituitary-adrenal cortex axis].
    Postepy higieny i medycyny doswiadczalnej, 1993, Volume: 47, Issue:3

    Topics: Circadian Rhythm; Endocrine System Diseases; Female; Humans; Hypothalamus; Melatonin; Pituitary-Adre

1993
Influence of melatonin and photoperiod on animal and human reproduction.
    Journal of endocrinological investigation, 1996, Volume: 19, Issue:6

    Topics: Animals; Female; Gonadal Steroid Hormones; Humans; Male; Melatonin; Organ Specificity; Photoperiod;

1996
Effects of melatonin infused into the III ventricle on prolactin, beta-endorphin and luteotropin secretion in ewes during the different stages of the reproductive cycle.
    Acta neurobiologiae experimentalis, 1996, Volume: 56, Issue:3

    Topics: Animals; beta-Endorphin; Female; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Melat

1996
Treatment of circadian rhythm disorders--melatonin.
    Chronobiology international, 1997, Volume: 14, Issue:2

    Topics: Adult; Aerospace Medicine; Aircraft; Animals; Circadian Rhythm; Darkness; Female; Humans; Light; Mel

1997
Melatonin: role in development.
    Journal of biological rhythms, 1997, Volume: 12, Issue:6

    Topics: Animals; Circadian Rhythm; Cricetinae; Embryonic and Fetal Development; Female; Fetus; Humans; Melat

1997
Safety of melatonin in long-term use (?)
    Journal of biological rhythms, 1997, Volume: 12, Issue:6

    Topics: Animals; Circadian Rhythm; Female; Humans; Melatonin; Photoperiod; Pregnancy

1997
Reproductive safety of melatonin: a "wonder drug" to wonder about.
    Journal of biological rhythms, 1997, Volume: 12, Issue:6

    Topics: Animals; Female; Humans; Melatonin; Pregnancy; Reproduction

1997
The pars tuberalis of the pituitary: a gateway for neuroendocrine output.
    Reviews of reproduction, 1996, Volume: 1, Issue:3

    Topics: Animals; Cell Communication; Female; Gene Expression; Humans; Male; Melatonin; Neurosecretory System

1996
Melatonin and human reproduction.
    Annals of medicine, 1998, Volume: 30, Issue:1

    Topics: Adult; Animals; Circadian Rhythm; Female; Humans; Male; Melatonin; Menopause; Middle Aged; Pineal Gl

1998
[Melatonin: a popular hormone].
    Minerva medica, 1998, Volume: 89, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Animals; Child; Child, Preschool; Circadian Rhythm; Con

1998
[Melatonin and its role the circadian function].
    Postepy higieny i medycyny doswiadczalnej, 1999, Volume: 53, Issue:3

    Topics: Animals; Biological Clocks; Brain; Circadian Rhythm; Female; Humans; Liver; Melatonin; Pineal Gland;

1999
The roles of melatonin in development.
    Advances in experimental medicine and biology, 1999, Volume: 460

    Topics: Animals; Circadian Rhythm; Embryonic and Fetal Development; Female; Growth; Mammals; Melatonin; Preg

1999
Melatonin and development: physiology and pharmacology.
    Seminars in perinatology, 2000, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aging; Child; Circadian Rhythm; Female; Fetus; Humans; Infant; Melatonin; Pregnan

2000
Chronobiological basis of female-specific mood disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:5 Suppl

    Topics: Antidepressive Agents, Second-Generation; Chronobiology Phenomena; Cross-Over Studies; Depression, P

2001
The development of circadian rhythms in the fetus and neonate.
    Seminars in perinatology, 2001, Volume: 25, Issue:6

    Topics: Animals; Circadian Rhythm; Dopamine; Female; Fetus; Humans; Infant, Newborn; Melatonin; Pregnancy; S

2001
Perinatal neuroendocrine regulation. Development of the circadian time-keeping system.
    Molecular and cellular endocrinology, 2002, Jan-25, Volume: 186, Issue:2

    Topics: Animals; Animals, Newborn; Body Temperature Regulation; Cebus; Circadian Rhythm; Female; Fetus; Gene

2002
[LH-RH (author's transl)].
    Nihon rinsho. Japanese journal of clinical medicine, 1978, Volume: 36, Issue:1

    Topics: Adult; Animals; Castration; Cattle; Child; Endocrine System Diseases; Estrus; Female; Gonadotropin-R

1978
Current status of pineal peptides.
    Neuroendocrinology, 1977, Volume: 24, Issue:3-4

    Topics: Animals; Female; Fertility; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Hypert

1977
Feedback control of pineal function by reproductive hormones--a neuroendocrine paradigm.
    Journal of neural transmission. Supplementum, 1978, Issue:13

    Topics: Acetyltransferases; Animals; Estradiol; Estrus; Female; Ganglia, Autonomic; Gonadal Steroid Hormones

1978
[Neurohumoral control of the pineal gland. A model for the study of neuroendocrine integrative processes].
    Acta physiologica latino americana, 1979, Volume: 29, Issue:6

    Topics: Animals; Cattle; Circadian Rhythm; Cricetinae; Depression, Chemical; Estrus; Female; Ganglia, Sympat

1979
The pineal gland and spontaneous abortions: implications for therapy with melatonin and magnetic field.
    The International journal of neuroscience, 1992, Volume: 62, Issue:3-4

    Topics: Abortion, Spontaneous; Female; Humans; Immunosuppression Therapy; Magnetics; Melatonin; Neuroimmunom

1992
Seasonality in human reproduction: an update.
    Human reproduction (Oxford, England), 1992, Volume: 7, Issue:6

    Topics: Animals; Cholecalciferol; Female; Humans; Melatonin; Pregnancy; Reproduction; Seasons

1992
The pineal gland and the clinical course of multiple sclerosis.
    The International journal of neuroscience, 1992, Volume: 62, Issue:1-2

    Topics: Calcinosis; Female; Humans; Melatonin; Middle Aged; Multiple Sclerosis; Pineal Gland; Postpartum Per

1992
Maternal programming of the fetal brain dictates the response of juvenile Siberian hamsters to photoperiod: dissecting the information transfer system.
    The Journal of experimental zoology. Supplement : published under auspices of the American Society of Zoologists and the Division of Comparative Physiology and Biochemistry, 1990, Volume: 4

    Topics: Animals; Brain; Cricetinae; Female; Lighting; Male; Maternal-Fetal Exchange; Melatonin; Neurosecreto

1990
[Neurohormonal regulation of lactation].
    Akusherstvo i ginekologiia, 1985, Issue:5

    Topics: Female; Growth Hormone; Humans; Hypothalamus; Lactation; Melatonin; Neurotransmitter Agents; Pineal

1985
Seasonality of reproduction in sheep and its control by photoperiod.
    Australian journal of biological sciences, 1988, Volume: 41, Issue:1

    Topics: Animals; Circadian Rhythm; Female; Gonadotropins; Gonads; Lactation; Light; Luteinizing Hormone; Mal

1988
Morphological and biochemical changes in the pineal gland in pregnancy.
    Life sciences, 1987, Dec-14, Volume: 41, Issue:24

    Topics: Animals; Cytoplasm; Female; Golgi Apparatus; Humans; Melatonin; Organoids; Pineal Gland; Pregnancy;

1987
Determinants of puberty in a seasonal breeder.
    Recent progress in hormone research, 1986, Volume: 42

    Topics: Aging; Animals; Estradiol; Estrus; Female; Fertility; Follicular Phase; Gonadotropins; Humans; Hypot

1986
Seasonal breeding in a marsupial: opportunities of a new species for an old problem.
    Recent progress in hormone research, 1986, Volume: 42

    Topics: Animals; Animals, Newborn; Bromocriptine; Circadian Rhythm; Corpus Luteum; Estrus; Female; Lactation

1986
Role of the pineal gland and melatonin in seasonal reproductive function in mammals.
    Oxford reviews of reproductive biology, 1986, Volume: 8

    Topics: Animals; Female; Male; Mammals; Melatonin; Pineal Gland; Pregnancy; Rats; Reproduction; Seasons; She

1986
Melatonin: a coordinating signal for mammalian reproduction?
    Science (New York, N.Y.), 1985, Feb-15, Volume: 227, Issue:4688

    Topics: Animals; Circadian Rhythm; Estrus; Female; Gonads; Hypothalamo-Hypophyseal System; Light; Male; Mamm

1985
Hypothalamic pulse generators.
    Recent progress in hormone research, 1985, Volume: 41

    Topics: Animals; Endorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Lactation; Luteinizing Ho

1985
Neural and hormonal regulation of pineal adenyl cyclase activity.
    Advances in biochemical psychopharmacology, 1970, Volume: 3

    Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Estradiol; Estrogens; Estrus; Feedback; Female; Fluorides; L

1970
The mammalian pineal as a neuroendocrine transducer.
    Recent progress in hormone research, 1969, Volume: 25

    Topics: Animals; Brain; Cats; Cattle; Circadian Rhythm; Endocrine Glands; Estrus; Female; Light; Melatonin;

1969
[Certain results and perspectives of the study of the role of the epiphysis in obstetrics and gynecology (literature survey)].
    Akusherstvo i ginekologiia, 1974, Issue:5

    Topics: Female; Humans; Hypogonadism; Labor, Obstetric; Lactation; Melatonin; Menopause; Menstruation; Ovari

1974

Trials

49 trials available for melatonin and Pregnancy

ArticleYear
The Role of Delivery Route on Colostrum Melatonin and Serum Il-6 Levels: a Prospective Controlled Study.
    Zeitschrift fur Geburtshilfe und Neonatologie, 2021, Volume: 225, Issue:6

    Topics: Cesarean Section; Colostrum; Delivery, Obstetric; Female; Humans; Interleukin-6; Melatonin; Pregnanc

2021
Infantile Cocktail of Erythropoietin and Melatonin Restores Gait in Adult Rats with Preterm Brain Injury.
    Developmental neuroscience, 2022, Volume: 44, Issue:4-5

    Topics: Animals; Brain Injuries; Erythropoietin; Female; Gait; Humans; Infant; Melatonin; Pregnancy; Prematu

2022
Melatonin Improves Quality of Repeated-Poor and Frozen-Thawed Embryos in Human, a Prospective Clinical Trial.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: bcl-2-Associated X Protein; Female; Humans; Melatonin; Pregnancy; Prospective Studies; Reactive Oxyg

2022
Biodynamic lighting conditions preserve nocturnal melatonin production in pregnant women during hospitalization: A randomized prospective pilot study.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Female; Hospitalization; Humans; Infant; Light; Lighting; Melatonin; Pilot Projects; Pregnancy; Preg

2022
Critically-timed sleep+light interventions differentially improve mood in pregnancy vs. postpartum depression by shifting melatonin rhythms.
    Journal of affective disorders, 2023, 03-01, Volume: 324

    Topics: Affect; Circadian Rhythm; Depression, Postpartum; Female; Humans; Melatonin; Pregnancy; Sleep

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Melatonin administration during the dry period stimulates subsequent milk yield and weight gain of offspring in subtropical does kidding in summer.
    Journal of dairy science, 2019, Volume: 102, Issue:12

    Topics: Animals; Female; Goats; Lactation; Male; Melatonin; Milk; Photoperiod; Pregnancy; Seasons; Triiodoth

2019
A double-blind randomised placebo-controlled trial of melatonin as an adjuvant agent in induction of labour (MILO): a study protocol.
    BMJ open, 2020, 02-12, Volume: 10, Issue:2

    Topics: Adult; Apgar Score; Australia; Cesarean Section; Delivery, Obstetric; Double-Blind Method; Drug Ther

2020
Exogenous melatonin and male foetuses improve the quality of sheep colostrum.
    Journal of animal physiology and animal nutrition, 2020, Volume: 104, Issue:5

    Topics: Animals; Animals, Newborn; Colostrum; Drug Implants; Female; Fetus; Litter Size; Male; Melatonin; Pr

2020
Greater concentrations of IGF-1 are associated with increasing pregnancy rate in melatonin implanted anestrous Barki ewes.
    Animal reproduction science, 2020, Volume: 219

    Topics: Animals; Delayed-Action Preparations; Drug Implants; Egypt; Estradiol; Estrus Synchronization; Femal

2020
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
The effect of myo-inositol, vitamin D3 and melatonin on the oocyte quality and pregnancy in in vitro fertilization: a randomized prospective controlled trial.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:16

    Topics: Adult; Cholecalciferol; Dose-Response Relationship, Drug; Female; Fertilization in Vitro; Humans; In

2020
Effects of nutrient restriction and melatonin supplementation from mid-to-late gestation on maternal and fetal small intestinal carbohydrase activities in sheep.
    Domestic animal endocrinology, 2021, Volume: 74

    Topics: Animal Feed; Animals; Caloric Restriction; Diet; Female; Fetal Development; Fetus; Gene Expression R

2021
Oral melatonin as a new tool for neuroprotection in preterm newborns: study protocol for a randomized controlled trial.
    Trials, 2021, Jan-22, Volume: 22, Issue:1

    Topics: Female; Humans; Infant; Infant, Newborn; Infant, Premature; Melatonin; Multicenter Studies as Topic;

2021
Maternal Serum Melatonin Increases During Pregnancy and Falls Immediately After Delivery Implicating the Placenta as a Major Source of Melatonin.
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Adolescent; Adult; Biomarkers; Cesarean Section; Circadian Rhythm; Delivery, Obstetric; Female; Huma

2020
The effect of oral melatonin supplementation on MT-ATP6 gene expression and IVF outcomes in Iranian infertile couples: a nonrandomized controlled trial.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:7

    Topics: Administration, Oral; Adult; Antioxidants; Cumulus Cells; Female; Fertilization in Vitro; Gene Expre

2021
Manipulation of reproductive seasonality using melatonin implantation in Anglo-Nubian does treated with controlled internal drug release and equine chorionic gonadotropin during the nonbreeding season.
    Journal of dairy science, 2017, Volume: 100, Issue:6

    Topics: Anestrus; Animal Husbandry; Animals; Drug Implants; Drug Liberation; Estradiol; Estrus Synchronizati

2017
Melatonin treatment in winter and spring and reproductive recovery in Sarda breed sheep.
    Animal reproduction science, 2017, Volume: 185

    Topics: Animals; Female; Male; Melatonin; Pregnancy; Reproduction; Seasons; Sheep

2017
Melatonin improves endothelial function in vitro and prolongs pregnancy in women with early-onset preeclampsia.
    Journal of pineal research, 2018, Volume: 65, Issue:3

    Topics: Adult; Endothelium, Vascular; Female; Humans; Melatonin; Pre-Eclampsia; Pregnancy

2018
Effect of chronic melatonin supplementation during mid to late gestation on maternal uterine artery blood flow and subsequent development of male offspring in beef cattle.
    Journal of animal science, 2018, Dec-03, Volume: 96, Issue:12

    Topics: Animals; Cattle; Dietary Supplements; Drug Implants; Female; Fetus; Male; Melatonin; Placenta; Pregn

2018
Early versus late wake therapy improves mood more in antepartum versus postpartum depression by differentially altering melatonin-sleep timing disturbances.
    Journal of affective disorders, 2019, 02-15, Volume: 245

    Topics: Adult; Affect; Circadian Rhythm; Depression, Postpartum; Depressive Disorder, Major; Female; Humans;

2019
Rapid Communication: Maternal melatonin implants improve fetal oxygen supply and body weight at term in sheep pregnancies.
    Journal of animal science, 2019, Feb-01, Volume: 97, Issue:2

    Topics: Animals; Animals, Newborn; Antioxidants; Birth Weight; Drug Implants; Female; Fetal Development; Mal

2019
Melatonin treatment and male replacement every week on the reproductive performance in Sarda sheep breed.
    Theriogenology, 2019, Sep-01, Volume: 135

    Topics: Animal Husbandry; Animals; Antioxidants; Female; Fertility; Male; Melatonin; Pregnancy; Pregnancy Ra

2019
Protect-me: a parallel-group, triple blinded, placebo-controlled randomised clinical trial protocol assessing antenatal maternal melatonin supplementation for fetal neuroprotection in early-onset fetal growth restriction.
    BMJ open, 2019, 06-22, Volume: 9, Issue:6

    Topics: Adult; Antioxidants; Female; Fetal Growth Retardation; Humans; Infant; Male; Melatonin; Neuroprotect

2019
Effect of exogenous melatonin on embryo viability and uterine environment in undernourished ewes.
    Animal reproduction science, 2013, Volume: 141, Issue:1-2

    Topics: Animal Feed; Animals; Diet; Embryo, Mammalian; Endometrium; Female; Malnutrition; Maternal Nutrition

2013
Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction.
    Journal of pineal research, 2014, Volume: 56, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Brain; Female; Fetal Growth Retardation; Humans; Melatonin;

2014
Oral melatonin supplementation improves oocyte and embryo quality in women undergoing in vitro fertilization-embryo transfer.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:5

    Topics: Administration, Oral; Adult; Female; Fertilization in Vitro; Humans; Infertility, Female; Male; Mela

2014
Positive effects of melatonin treatment on the reproductive performance of young border leicester rams mated to merino ewes in spring: preliminary observations.
    Reproduction in domestic animals = Zuchthygiene, 2014, Volume: 49, Issue:6

    Topics: Animals; Drug Implants; Female; Fertility Agents, Male; Male; Melatonin; Pregnancy; Pregnancy Rate;

2014
A pilot double-blind randomised placebo-controlled dose-response trial assessing the effects of melatonin on infertility treatment (MIART): study protocol.
    BMJ open, 2014, Sep-01, Volume: 4, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Deoxyguanosine; Dietary Supplements; Double-Blind Method;

2014
Effects of nutrient restriction and melatonin supplementation on maternal and foetal hepatic and small intestinal energy utilization.
    Journal of animal physiology and animal nutrition, 2014, Volume: 98, Issue:4

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Supplements; Female;

2014
Effect of melatonin or maternal nutrient restriction on vascularity and cell proliferation in the ovine placenta.
    Animal reproduction science, 2015, Volume: 153

    Topics: Animal Nutritional Physiological Phenomena; Animals; Blood Vessels; Caloric Restriction; Cell Count;

2015
Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2016, Volume: 32, Issue:1

    Topics: Adult; Antioxidants; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Embryo Tra

2016
Influence of nutrient restriction and melatonin supplementation of pregnant ewes on maternal and fetal pancreatic digestive enzymes and insulin-containing clusters.
    Animal : an international journal of animal bioscience, 2016, Volume: 10, Issue:3

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Supplements; Female;

2016
Dietary melatonin alters uterine artery hemodynamics in pregnant Holstein heifers.
    Domestic animal endocrinology, 2016, Volume: 55

    Topics: Animal Feed; Animals; Body Composition; Cattle; Diet; Dietary Supplements; Female; Hemodynamics; Mel

2016
Effects of Supplementing Holstein Heifers with Dietary Melatonin during Late Gestation on Growth and Cardiovascular Measurements of their Offspring.
    Reproduction in domestic animals = Zuchthygiene, 2016, Volume: 51, Issue:2

    Topics: Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Blood Pressure; Cattle; Dietary S

2016
Manipulation of reproductive performance of lactating buffaloes using melatonin and controlled internal drug release device treatment during out-of-breeding season under tropical conditions.
    Theriogenology, 2016, Sep-01, Volume: 86, Issue:4

    Topics: Administration, Intravaginal; Animals; Buffaloes; Chorionic Gonadotropin; Drug Contamination; Drug I

2016
Evaluation of the influence of melatonin implants during the gestation period in sheep from a selenium-deficient region.
    American journal of veterinary research, 2009, Volume: 70, Issue:3

    Topics: Animals; Animals, Newborn; Drug Implants; Female; Glutathione Peroxidase; Melatonin; Pregnancy; Seas

2009
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:6

    Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Humans; Inositol; Melatonin; Oocytes; Pregnancy;

2010
Effect of melatonin implants on the incidence and timing of puberty in female red deer (Cervus elaphus).
    Animal reproduction science, 2011, Volume: 123, Issue:3-4

    Topics: Animals; Deer; Drug Implants; Estrus Synchronization; Female; Fertilization; Incidence; Melatonin; P

2011
Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:11

    Topics: Adult; Cohort Studies; Female; Fertilization in Vitro; Follicle Stimulating Hormone, Human; Humans;

2011
Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:11

    Topics: Adult; Cohort Studies; Female; Fertilization in Vitro; Follicle Stimulating Hormone, Human; Humans;

2011
Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:11

    Topics: Adult; Cohort Studies; Female; Fertilization in Vitro; Follicle Stimulating Hormone, Human; Humans;

2011
Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:11

    Topics: Adult; Cohort Studies; Female; Fertilization in Vitro; Follicle Stimulating Hormone, Human; Humans;

2011
Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems.
    Journal of assisted reproduction and genetics, 2011, Volume: 28, Issue:9

    Topics: Central Nervous System Depressants; Embryo Transfer; Embryo, Mammalian; Female; Fertilization in Vit

2011
The efficacy of melatonin administration on oocyte quality.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:2

    Topics: Adult; Embryo Transfer; Female; Fertilization in Vitro; Free Radical Scavengers; Humans; Melatonin;

2012
Enhancement of the male effect on reproductive performance in female Mediterranean goats with long day and/or melatonin treatment.
    Veterinary journal (London, England : 1997), 2012, Volume: 192, Issue:3

    Topics: Animals; Drug Implants; Female; Goats; Litter Size; Male; Melatonin; Ovulation; Photoperiod; Pregnan

2012
Vaccination prepartum enhances the beneficial effects of melatonin on the immune response and reduces platelet responsiveness in sheep.
    BMC veterinary research, 2012, Jun-20, Volume: 8

    Topics: Adjuvants, Immunologic; Animals; Bacterial Vaccines; Clostridium Infections; Clostridium perfringens

2012
Does supplementation of in-vitro culture medium with melatonin improve IVF outcome in PCOS?
    Reproductive biomedicine online, 2013, Volume: 26, Issue:1

    Topics: Adult; Culture Media; Embryo Implantation; Enzyme-Linked Immunosorbent Assay; Female; Fertilization

2013
Randomized clinical trial of bright light therapy for antepartum depression: preliminary findings.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:3

    Topics: Adult; Circadian Rhythm; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Dis

2004
Effects of night work on urinary excretion rates of 6-sulfatoxymelatonin, norepinephrine and estriol in pregnant women.
    Industrial health, 2004, Volume: 42, Issue:2

    Topics: Adult; Analysis of Variance; Estriol; Female; Humans; Melatonin; Norepinephrine; Nursing Staff; Pers

2004
Serum thyroid hormones and performance of offspring in ewes receiving propylthiouracil with or without melatonin.
    Animal reproduction science, 2007, Volume: 100, Issue:1-2

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Estrous Cycle; Female; Hypothyroidism; Melat

2007
Chronobiological basis of female-specific mood disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:5 Suppl

    Topics: Antidepressive Agents, Second-Generation; Chronobiology Phenomena; Cross-Over Studies; Depression, P

2001

Other Studies

597 other studies available for melatonin and Pregnancy

ArticleYear
Melatonin is involved in the modulation of the hypothalamic and pituitary activity in the South American plains vizcacha, Lagostomus maximus.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2022, Volume: 192, Issue:1

    Topics: Animals; Female; Hypothalamus; Luteinizing Hormone; Melatonin; Pituitary Gland; Pregnancy; South Ame

2022
Melatonin improves the quality of frozen bull semen and influences gene expression related to embryo genome activation.
    Theriogenology, 2021, Volume: 176

    Topics: Animals; Cattle; Cryopreservation; Embryo, Mammalian; Female; Gene Expression; Male; Melatonin; Preg

2021
Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy.
    Journal of pineal research, 2022, Volume: 72, Issue:1

    Topics: Animals; Female; Fetal Growth Retardation; Hypoxia; Melatonin; Pregnancy; Pregnancy Complications; R

2022
Partial protective effects of melatonin on developing brain in a rat model of chorioamnionitis.
    Scientific reports, 2021, 11-12, Volume: 11, Issue:1

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Brain; Chorioamnionitis; Cytokines; Disease Mod

2021
Expression of arylalkylamine n-acetyltransferase (AANAT) and acetylserotonin o-methyltransferase (ASMT) in the corpus luteum of pregnant sows and synthesis of melatonin in luteal cells.
    Cell and tissue research, 2022, Volume: 388, Issue:1

    Topics: Acetylserotonin O-Methyltransferase; Animals; Arylalkylamine N-Acetyltransferase; Corpus Luteum; Fem

2022
Effects of melatonin on the production of GnRH and LH in luteal cells of pregnant sows.
    Journal of molecular endocrinology, 2022, 01-20, Volume: 68, Issue:2

    Topics: Animals; Female; Gonadotropin-Releasing Hormone; Luteal Cells; Luteinizing Hormone; Melatonin; Pregn

2022
Melatonin Administration Prevents Placental and Fetal Changes Induced by Gestational Diabetes.
    Reproductive sciences (Thousand Oaks, Calif.), 2022, Volume: 29, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes, Gestational; Female; Fetus; Humans; Melatonin; P

2022
Effect of circadian system disruption on the concentration and daily oscillations of cortisol, progesterone, melatonin, serotonin, growth hormone, and core body temperature in periparturient dairy cattle.
    Journal of dairy science, 2022, Volume: 105, Issue:3

    Topics: Animals; Bayes Theorem; Body Temperature; Cattle; Female; Growth Hormone; Hydrocortisone; Lactation;

2022
Longitudinal Changes in Sleep, Biological Rhythms, and Light Exposure From Late Pregnancy to Postpartum and Their Impact on Peripartum Mood and Anxiety.
    The Journal of clinical psychiatry, 2022, 01-18, Volume: 83, Issue:2

    Topics: Actigraphy; Adult; Affect; Anxiety; Circadian Rhythm; Depression, Postpartum; Female; Humans; Longit

2022
Are alterations in melatonin and inflammatory cytokine serum levels linked with recurrent abortion in pregnant women with acute toxoplasmosis: The interacted nexus.
    JPMA. The Journal of the Pakistan Medical Association, 2021, Volume: 71(Suppl 8), Issue:12

    Topics: Abortion, Habitual; Case-Control Studies; Cytokines; Female; Humans; Melatonin; Pregnancy; Pregnant

2021
Melatonin regulates trophoblast pyroptosis, invasion and migration in preeclampsia by inhibiting HtrA1 transcription through the microRNA-520c-3p/SETD7 axis.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2022, Volume: 87, Issue:4

    Topics: Cell Movement; Cell Proliferation; Female; High-Temperature Requirement A Serine Peptidase 1; Histon

2022
Melatonin treatment during chronic hypoxic gestation improves neonatal cerebrovascular function.
    Vascular pharmacology, 2022, Volume: 144

    Topics: Animals; Antioxidants; Female; Hypoxia; Lung; Melatonin; Oxidative Stress; Pregnancy; Sheep

2022
Women with polycystic ovary syndrome (PCOS) have reduced melatonin concentrations in their follicles and have mild sleep disturbances.
    BMC women's health, 2022, 03-21, Volume: 22, Issue:1

    Topics: Female; Fertilization in Vitro; Follicular Fluid; Humans; Melatonin; Polycystic Ovary Syndrome; Preg

2022
Effects of the maternal gut microbiome and gut-placental axis on melatonin efficacy in alleviating cadmium-induced fetal growth restriction.
    Ecotoxicology and environmental safety, 2022, Jun-01, Volume: 237

    Topics: Animals; Cadmium; Female; Fetal Growth Retardation; Gastrointestinal Microbiome; Humans; Melatonin;

2022
New insights into the reverse of chromium-induced reprotoxicity of pregnant mice by melatonin.
    Ecotoxicology and environmental safety, 2022, Jun-15, Volume: 238

    Topics: Animals; Chromium; Female; Follicular Atresia; Melatonin; Mice; Ovary; Pregnancy; Pregnancy Outcome

2022
Protective Effect of Melatonin on Nonylphenol-Induced Reproductive and Behavioral Disorders in First-Generation Adult Male Rats.
    Behavioural neurology, 2022, Volume: 2022

    Topics: Animals; Antioxidants; Female; Male; Melatonin; Oxidative Stress; Phenols; Pregnancy; Rats; Rats, Wi

2022
Oxidative stress induces meiotic defects of oocytes in a mouse psoriasis model.
    Cell death & disease, 2022, 05-19, Volume: 13, Issue:5

    Topics: Animals; Female; Meiosis; Melatonin; Mice; Mitochondria; Oocytes; Oxidative Stress; Pregnancy; Psori

2022
Melatonin regulates proliferation, apoptosis and invasion of trophoblasts in preeclampsia by inhibiting endoplasmic reticulum stress.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2022, Volume: 88, Issue:2

    Topics: Animals; Apoptosis; Cell Movement; Cell Proliferation; Endoplasmic Reticulum Stress; Female; Humans;

2022
Sex-Dependent Effects of Piromelatine Treatment on Sleep-Wake Cycle and Sleep Structure of Prenatally Stressed Rats.
    International journal of molecular sciences, 2022, Sep-08, Volume: 23, Issue:18

    Topics: Animals; Brain-Derived Neurotrophic Factor; Circadian Rhythm; Electroencephalography; Female; Indole

2022
Seasonal and temporal variation in the placenta during melatonin supplementation in a bovine compromised pregnancy model.
    Journal of animal science, 2022, Dec-01, Volume: 100, Issue:12

    Topics: Animals; ARNTL Transcription Factors; Cattle; Cattle Diseases; Dietary Supplements; Female; Fetal Gr

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Animals; Corpus Luteum; Female; Luteinization; Melatonin; Mice; Mice, Inbred ICR; Ovary; Pregnancy;

2023
Maternal nutrient restriction and dietary melatonin alter neurotransmitter pathways in placental and fetal tissues.
    Placenta, 2023, Volume: 131

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cattle; Female; Fetus; Maternal Nutritional Phy

2023
Maternal nutrient restriction and dietary melatonin alter neurotransmitter pathways in placental and fetal tissues.
    Placenta, 2023, Volume: 131

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cattle; Female; Fetus; Maternal Nutritional Phy

2023
Maternal nutrient restriction and dietary melatonin alter neurotransmitter pathways in placental and fetal tissues.
    Placenta, 2023, Volume: 131

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cattle; Female; Fetus; Maternal Nutritional Phy

2023
Maternal nutrient restriction and dietary melatonin alter neurotransmitter pathways in placental and fetal tissues.
    Placenta, 2023, Volume: 131

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cattle; Female; Fetus; Maternal Nutritional Phy

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Artificial Dim Light at Night during Pregnancy Can Affect Hormonal and Metabolic Rhythms in Rat Offspring.
    International journal of molecular sciences, 2022, Nov-22, Volume: 23, Issue:23

    Topics: Animals; Circadian Rhythm; Corticosterone; Female; Light; Melatonin; Pregnancy; Rats

2022
Artificial Dim Light at Night during Pregnancy Can Affect Hormonal and Metabolic Rhythms in Rat Offspring.
    International journal of molecular sciences, 2022, Nov-22, Volume: 23, Issue:23

    Topics: Animals; Circadian Rhythm; Corticosterone; Female; Light; Melatonin; Pregnancy; Rats

2022
Artificial Dim Light at Night during Pregnancy Can Affect Hormonal and Metabolic Rhythms in Rat Offspring.
    International journal of molecular sciences, 2022, Nov-22, Volume: 23, Issue:23

    Topics: Animals; Circadian Rhythm; Corticosterone; Female; Light; Melatonin; Pregnancy; Rats

2022
Artificial Dim Light at Night during Pregnancy Can Affect Hormonal and Metabolic Rhythms in Rat Offspring.
    International journal of molecular sciences, 2022, Nov-22, Volume: 23, Issue:23

    Topics: Animals; Circadian Rhythm; Corticosterone; Female; Light; Melatonin; Pregnancy; Rats

2022
Role of melatonin receptor 1B gene polymorphism and its effect on the regulation of glucose transport in gestational diabetes mellitus.
    Journal of Zhejiang University. Science. B, 2023, Jan-15, Volume: 24, Issue:1

    Topics: Blood Glucose; Diabetes, Gestational; Female; Glucose; Humans; Melatonin; Polymorphism, Genetic; PPA

2023
Sex-Dependent Effect of Chronic Piromelatine Treatment on Prenatal Stress-Induced Memory Deficits in Rats.
    International journal of molecular sciences, 2023, Jan-09, Volume: 24, Issue:2

    Topics: Animals; Female; Hippocampus; Indoles; Male; Maze Learning; Melatonin; Memory Disorders; Pregnancy;

2023
Disruption of the Expression of the Placental Clock and Melatonin Genes in Preeclampsia.
    International journal of molecular sciences, 2023, Jan-25, Volume: 24, Issue:3

    Topics: Animals; Circadian Rhythm; CLOCK Proteins; Female; Humans; Melatonin; Placenta; Pre-Eclampsia; Pregn

2023
Leptin, Adiponectin, and Melatonin Modulate Colostrum Lymphocytes in Mothers with Obesity.
    International journal of molecular sciences, 2023, Jan-31, Volume: 24, Issue:3

    Topics: Adiponectin; Calcium; Colostrum; Cross-Sectional Studies; Female; Humans; Infant; Infant, Newborn; L

2023
Prevalence and risk factors of sub-health and circadian rhythm disorder of cortisol, melatonin, and temperature among Chinese midwives.
    Frontiers in public health, 2023, Volume: 11

    Topics: Chronobiology Disorders; Cross-Sectional Studies; East Asian People; Female; Humans; Hydrocortisone;

2023
Effects of prenatal and postnatal melatonin supplementation on overall performance, male reproductive performance, and testicular hemodynamics in beef cattle.
    Journal of animal science, 2023, Jan-03, Volume: 101

    Topics: Animals; Birth Weight; Cattle; Dietary Supplements; Female; Hemodynamics; Male; Melatonin; Milk; Par

2023
Melatonin administration during the first half of pregnancy improves the reproductive performance of rabbits: Emphasis on ovarian and placental functions.
    Theriogenology, 2023, Jul-15, Volume: 205

    Topics: Animals; Female; Melatonin; Ovary; Parturition; Placenta; Pregnancy; Pregnancy Outcome; Rabbits

2023
Reproductive performance of hair ewes and rams implanted with melatonin previous to the anestrus season in northwest Mexico.
    Tropical animal health and production, 2023, Apr-26, Volume: 55, Issue:3

    Topics: Anestrus; Animals; Female; Male; Melatonin; Mexico; Pregnancy; Seasons; Semen; Sheep; Sheep, Domesti

2023
The Uterine Melatonergic Systems of AANAT and Melatonin Membrane Receptor 2 (MT2) Are Essential for Endometrial Receptivity and Early Implantation in Mice.
    International journal of molecular sciences, 2023, Apr-12, Volume: 24, Issue:8

    Topics: Acetyltransferases; Animals; Arylalkylamine N-Acetyltransferase; Endometrium; Female; Humans; Melato

2023
Postnatal melatonin administration to stressed dams for ameliorating risk-taking behaviour in rat pups through maternal care improvement.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2023, Volume: 83, Issue:4

    Topics: Animals; Anxiety; Corticosterone; Female; Humans; Melatonin; Pregnancy; Prenatal Exposure Delayed Ef

2023
Melatonin alleviates cisplatin-induced mice spermatogenesis defects.
    Reproductive toxicology (Elmsford, N.Y.), 2023, Volume: 119

    Topics: Animals; Antioxidants; Cisplatin; Female; Male; Melatonin; Mice; Oxidative Stress; Pregnancy; Semen;

2023
Changes in concentrations of melatonin, PlGF, and cytokines in women with preeclampsia.
    Journal of medicine and life, 2023, Volume: 16, Issue:3

    Topics: Biomarkers; Cytokines; Female; Humans; Interleukin-10; Interleukin-6; Melatonin; Placenta; Placenta

2023
Melatonin modulates endometrial decidualization via NOTCH1-NRF2-FOXO1-GSH pathway†.
    Biology of reproduction, 2023, 09-12, Volume: 109, Issue:3

    Topics: Decidua; Endometrium; Female; Forkhead Box Protein O1; Glutathione; Humans; Melatonin; NF-E2-Related

2023
Maternal melatonin levels and temporal dietary intake: results from MY-CARE cohort study.
    BMC pregnancy and childbirth, 2023, Jul-04, Volume: 23, Issue:1

    Topics: Carbohydrates; Cohort Studies; Eating; Energy Intake; Female; Humans; Melatonin; Pregnancy; Prospect

2023
Mental health, sleep quality, and hormonal circadian rhythms in pregnant women with threatened preterm labor: a prospective observational study.
    BMC pregnancy and childbirth, 2023, Jul-07, Volume: 23, Issue:1

    Topics: Child; Circadian Rhythm; Female; Humans; Hydrocortisone; Infant, Newborn; Melatonin; Mental Health;

2023
Absence of melatonin during development impairs craniofacial and dental onset in rats.
    Clinical oral investigations, 2023, Volume: 27, Issue:9

    Topics: Animals; Female; Humans; Melatonin; Pineal Gland; Pregnancy; Rats; Rats, Wistar; RNA, Messenger

2023
Melatonin restores the declining maturation quality and early embryonic development of oocytes in aged mice.
    Theriogenology, 2023, Oct-15, Volume: 210

    Topics: Animals; Antioxidants; Embryonic Development; Female; In Vitro Oocyte Maturation Techniques; Mammals

2023
Methadone administered to rat dams during pregnancy and lactation affects the circadian rhythms of their pups.
    Journal of neuroscience research, 2023, Volume: 101, Issue:11

    Topics: Animals; Circadian Rhythm; Female; Lactation; Melatonin; Methadone; Pineal Gland; Pregnancy; Rats; S

2023
Polarization of Melatonin-Modulated Colostrum Macrophages in the Presence of Breast Tumor Cell Lines.
    International journal of molecular sciences, 2023, Aug-03, Volume: 24, Issue:15

    Topics: Breast Neoplasms; Cell Line, Tumor; Colostrum; Female; Humans; Macrophages; Melatonin; Pregnancy; Re

2023
Melatonin associated with a high-fat diet during pregnancy and lactation prevents liver changes in the offspring.
    General and comparative endocrinology, 2023, 11-01, Volume: 343

    Topics: Animals; Cholesterol; Diet, High-Fat; Female; Lactation; Liver; Melatonin; Pregnancy; Rats

2023
Plasma melatonin concentration during the early post-partum period in Thoroughbred mares and their foals.
    Acta veterinaria Hungarica, 2023, 10-17, Volume: 71, Issue:2

    Topics: Animals; Female; Horses; Melatonin; Parturition; Postpartum Period; Pregnancy

2023
The potential protective effects of melatonin and omega-3 on the male rat optic nerve exposed to 900 MHz electromagnetic radiation during the prenatal period.
    The International journal of neuroscience, 2023, Volume: 133, Issue:12

    Topics: Adolescent; Animals; Antioxidants; Child; Electromagnetic Fields; Electromagnetic Radiation; Female;

2023
MiR-126 and miR-146a as Melatonin-Responsive Biomarkers for Neonatal Brain Ischemia.
    Journal of molecular neuroscience : MN, 2023, Volume: 73, Issue:9-10

    Topics: Animals; Animals, Newborn; Biomarkers; Brain; Brain Injuries; Female; Hypoxia-Ischemia, Brain; Ische

2023
Gut microbiota-bile acid-vitamin D axis plays an important role in determining oocyte quality and embryonic development.
    Clinical and translational medicine, 2023, Volume: 13, Issue:10

    Topics: Animals; Bile Acids and Salts; Embryonic Development; Female; Gastrointestinal Microbiome; Lithochol

2023
Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague-Dawley rats.
    Journal of reproductive immunology, 2023, Volume: 160

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Fetus; Interleukin-6; Melatonin; Place

2023
Relationship Between Genetic Variant Of OXTR (Rs53576) And MTNR1B (Rs1387153) And Symptoms Of Psychological Stress In Females With Gestational Diabetes Mellitus.
    JPMA. The Journal of the Pakistan Medical Association, 2023, Volume: 73, Issue:11

    Topics: Adult; Case-Control Studies; Diabetes, Gestational; Female; Genotype; Humans; Melatonin; Polymorphis

2023
Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring.
    Medical hypotheses, 2019, Volume: 132

    Topics: Circadian Rhythm; Energy Metabolism; Female; Fetus; Glucose Intolerance; Humans; Insulin Resistance;

2019
Cell-free nucleic acids and melatonin levels in human follicular fluid predict embryo quality in patients undergoing in-vitro fertilization treatment.
    Journal of gynecology obstetrics and human reproduction, 2020, Volume: 49, Issue:1

    Topics: Adult; Cell-Free Nucleic Acids; Chorionic Gonadotropin; DNA; DNA Copy Number Variations; DNA Fragmen

2020
Effects of feeding melatonin during proestrus and early gestation to gilts and parity 1 sows to minimize effects of seasonal infertility1.
    Journal of animal science, 2019, Nov-04, Volume: 97, Issue:11

    Topics: Animals; Breeding; Estrus; Female; Fertility; Lactation; Light; Litter Size; Melatonin; Parity; Preg

2019
Genotoxic and mutagenic evaluation of the protective effect of exogenous melatonin in adult rats and their offspring exposed to the insecticides methomyl and cypermethrin during pregnancy.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2019, Volume: 848

    Topics: Animals; Female; Insecticides; Male; Maternal Exposure; Melatonin; Methomyl; Micronucleus Tests; Pre

2019
Variations in melatonin levels in preterm and term human breast milk during the first month after delivery.
    Scientific reports, 2019, 11-29, Volume: 9, Issue:1

    Topics: Adult; Biological Variation, Individual; Breast Feeding; Circadian Rhythm; Female; Humans; Infant Nu

2019
Exposure to chronic light-dark phase shifts during the prepartum nonlactating period attenuates circadian rhythms, decreases blood glucose, and increases milk yield in the subsequent lactation.
    Journal of dairy science, 2020, Volume: 103, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Temperature; Cattle; Circadian Rhythm; Diet; Fat

2020
Melatonin mitigates hippocampal and cognitive impairments caused by prenatal irradiation.
    The European journal of neuroscience, 2020, Volume: 52, Issue:6

    Topics: Animals; Cognitive Dysfunction; Female; Hippocampus; Male; Melatonin; Neurogenesis; Neurons; Pregnan

2020
Melatonin Protects Rabbit Somatic Cell Nuclear Transfer (SCNT) Embryos from Electrofusion Damage.
    Scientific reports, 2020, 02-10, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Blastocyst; Embryo Transfer; Embryonic Development; Endoplasmic Reticulum Stress

2020
Circadian rhythm and its association with birth and infant outcomes: research protocol of a prospective cohort study.
    BMC pregnancy and childbirth, 2020, Feb-11, Volume: 20, Issue:1

    Topics: Actigraphy; Adult; Circadian Rhythm; Diet Surveys; Eating; Female; Gestational Weight Gain; Humans;

2020
Expression of melatonin receptors and CD4 in the ovine thymus, lymph node, spleen and liver during early pregnancy.
    Immunology, 2020, Volume: 160, Issue:1

    Topics: Animals; CD4 Antigens; Female; Gene Expression Profiling; Histocompatibility, Maternal-Fetal; Immune

2020
Delayed sleep timing and circadian rhythms in pregnancy and transdiagnostic symptoms associated with postpartum depression.
    Translational psychiatry, 2020, 01-21, Volume: 10, Issue:1

    Topics: Actigraphy; Circadian Rhythm; Depression, Postpartum; Female; Humans; Melatonin; Pregnancy; Sleep

2020
Effect of melatonin on gonad and thyroid development of offspring of hypothyroid pregnant rats.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2020, Volume: 95, Issue:7

    Topics: Animals; Antioxidants; Antithyroid Agents; Female; Gonads; Hypothyroidism; Melatonin; Pregnancy; Pre

2020
Higher doses of Melatonin affect ovarian and middle uterine arteries vascular blood flow and induce oestrus earlier in acyclic ewes.
    Reproduction in domestic animals = Zuchthygiene, 2020, Volume: 55, Issue:7

    Topics: Animals; Blood Flow Velocity; Estrus; Female; Injections, Intramuscular; Melatonin; Ovary; Pregnancy

2020
Antiphospholipid antibodies can specifically target placental mitochondria and induce ROS production.
    Journal of autoimmunity, 2020, Volume: 111

    Topics: Antibodies, Antiphospholipid; Cell Respiration; Cells, Cultured; Chloroquine; Female; Glycerol-3-Pho

2020
Melatonin ameliorates murine fetal oocyte meiotic dysfunction in F1 and F2 offspring caused by nicotine exposure during pregnancy.
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 263, Issue:Pt A

    Topics: Animals; Female; Humans; Hydrogen Peroxide; Meiosis; Melatonin; Mice; Nicotine; Oocytes; Pregnancy

2020
Melatonin improves uterine-conceptus interaction via regulation of SIRT1 during early pregnancy.
    Journal of pineal research, 2020, Volume: 69, Issue:2

    Topics: Animals; Embryo, Mammalian; Female; Maternal-Fetal Exchange; Melatonin; Pregnancy; Sirtuin 1; Swine;

2020
Melatonin attenuates hypertension and oxidative stress in a rat model of L-NAME-induced gestational hypertension.
    Vascular medicine (London, England), 2020, Volume: 25, Issue:4

    Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Female; Heme

2020
Effects of altered photoperiod due to COVID-19 lockdown on pregnant women and their fetuses.
    Chronobiology international, 2020, Volume: 37, Issue:7

    Topics: Betacoronavirus; Circadian Clocks; Circadian Rhythm; Coronavirus Infections; COVID-19; Female; Fetus

2020
The Melatonin and Enriched Environment Ameliorated Low Protein-Induced Intrauterine Growth Retardation by IGF-1 And mtor Signaling Pathway and Autophagy Inhibition in Rats.
    Current molecular medicine, 2021, Volume: 21, Issue:3

    Topics: Animals; Autophagy; Diet, Protein-Restricted; Disease Models, Animal; Female; Fetal Growth Retardati

2021
Melatonin for prevention of fetal lung injury associated with intrauterine inflammation and for improvement of lung maturation.
    Journal of pineal research, 2020, Volume: 69, Issue:3

    Topics: Animals; Female; Fetal Diseases; Fetus; Inflammation; Lung; Lung Injury; Melatonin; Mice; Pregnancy

2020
Dramatically altered environmental lighting conditions in women with high-risk pregnancy during hospitalization.
    Chronobiology international, 2020, Volume: 37, Issue:8

    Topics: Circadian Rhythm; Female; Hospitalization; Humans; Infant, Newborn; Lighting; Melatonin; Pregnancy;

2020
Editorial: Decoding the Fetal Circadian System and Its Role in Adult Sickness and Health: Melatonin, a Dark History.
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Animals; Circadian Rhythm; Female; Fetal Development; Humans; Melatonin; Pregnancy

2020
Melatonin regulates oxidative stress and apoptosis in fetal hearts of pinealectomised RUPP rats.
    Hypertension in pregnancy, 2020, Volume: 39, Issue:4

    Topics: Animals; Apoptosis; Blood Pressure; Female; Fetal Heart; Melatonin; Oxidative Stress; Pinealectomy;

2020
Treatment of rams with melatonin implants in the non-breeding season improves post-thaw sperm progressive motility and DNA integrity.
    Animal reproduction science, 2020, Volume: 221

    Topics: Animals; Cryopreservation; DNA; Drug Implants; Female; Fertility; Male; Melatonin; Pregnancy; Pregna

2020
The Role of Melatonin, IL-8 and IL-10 in Intrahepatic Cholestasis of Pregnancy.
    Zeitschrift fur Geburtshilfe und Neonatologie, 2021, Volume: 225, Issue:3

    Topics: Cholestasis, Intrahepatic; Female; Humans; Interleukin-10; Interleukin-8; Melatonin; Pregnancy; Preg

2021
Saying NO to fetal growth restriction: Implications for beetroot juice and melatonin.
    The Journal of physiology, 2020, Volume: 598, Issue:24

    Topics: Animals; Beta vulgaris; Blood Pressure; Female; Fetal Growth Retardation; Melatonin; Mice; Nitrates;

2020
The protective role of melatonin against the effects of different doses of caffeine on the fetus.
    Cellular and molecular biology (Noisy-le-Grand, France), 2020, Jul-31, Volume: 66, Issue:5

    Topics: Animals; Antioxidants; Biomarkers; Bone and Bones; Caffeine; Female; Fetus; Inflammation; Liver; Mal

2020
Maternal melatonin implants improve twin Merino lamb survival.
    Journal of animal science, 2020, Nov-01, Volume: 98, Issue:11

    Topics: Animals; Australia; Birth Weight; Female; Melatonin; Parturition; Pregnancy; Sheep; Sheep, Domestic

2020
Mitochondrial function, blastocyst development and live foals born after ICSI of immature vitrified/warmed equine oocytes matured with or without melatonin.
    Theriogenology, 2021, Jan-15, Volume: 160

    Topics: Animals; Blastocyst; Cryopreservation; Embryonic Development; Female; Horses; Male; Melatonin; Mitoc

2021
Supplementing Merino ewes with melatonin during the last half of pregnancy improves tolerance of prolonged parturition and survival of second-born twin lambs.
    Journal of animal science, 2020, Dec-01, Volume: 98, Issue:12

    Topics: Animals; Birth Weight; Dietary Supplements; Female; Melatonin; Parturition; Pregnancy; Sheep; Sheep,

2020
Melatonin alleviates benzo(a)pyrene-induced ovarian corpus luteum dysfunction by suppressing excessive oxidative stress and apoptosis.
    Ecotoxicology and environmental safety, 2021, Jan-01, Volume: 207

    Topics: Animals; Antioxidants; Apoptosis; Benzo(a)pyrene; Corpus Luteum; Endocrine Disruptors; Female; Human

2021
Attenuation of chronic arsenic neurotoxicity via melatonin in male offspring of maternal rats exposed to arsenic during conception: Involvement of oxidative DNA damage and inflammatory signaling cascades.
    Life sciences, 2021, Feb-01, Volume: 266

    Topics: Animals; Antioxidants; Apoptosis; Arsenic; Female; Inflammation; Male; Melatonin; Neuroprotective Ag

2021
Seven-week asynchronous twins in a buffalo heifer (Bubalus bubalis) associated with superfetation - A case report.
    Reproduction in domestic animals = Zuchthygiene, 2021, Volume: 56, Issue:3

    Topics: Animals; Buffaloes; Estrus; Female; Male; Melatonin; Pregnancy; Progesterone; Superfetation

2021
Association between circadian rhythm disruption and polycystic ovary syndrome.
    Fertility and sterility, 2021, Volume: 115, Issue:3

    Topics: Adult; Animals; Animals, Newborn; Chronobiology Disorders; Circadian Rhythm; Female; Granulosa Cells

2021
Ameliorative effect of melatonin on apoptosis, DNA fragmentation, membrane integrity and lipid peroxidation of spermatozoa in the idiopathic asthenoteratospermic men: In vitro.
    Andrologia, 2021, Volume: 53, Issue:2

    Topics: Apoptosis; DNA Fragmentation; Female; Humans; Lipid Peroxidation; Male; Melatonin; Pregnancy; Semen

2021
Melatonin protects against environmental stress-induced fetal growth restriction via suppressing ROS-mediated GCN2/ATF4/BNIP3-dependent mitophagy in placental trophoblasts.
    Redox biology, 2021, Volume: 40

    Topics: Activating Transcription Factor 4; Adult; Animals; Case-Control Studies; Female; Fetal Growth Retard

2021
Melatonin regulates maternal pancreatic remodeling and B-cell function during pregnancy and lactation.
    Journal of pineal research, 2021, Volume: 71, Issue:1

    Topics: Animals; Female; Glucose; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Lactatio

2021
Developmental Programming: Physiological Impacts of Prenatal Melatonin Administration on Reproductive Capacity and Serum Triiodothyronine of Adult Female Offspring Rat Born to Moms Exposed to Bisphenol A During Pregnancy.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:7

    Topics: Animals; Benzhydryl Compounds; Female; Melatonin; Phenols; Pregnancy; Prenatal Exposure Delayed Effe

2021
Impact of Melatonin on Full-Term Fetal Brain Development and Transforming Growth Factor-β Level in a Rat Model of Preeclampsia.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:8

    Topics: Animals; Brain; Disease Models, Animal; Female; Malondialdehyde; Melatonin; Oxidative Stress; Placen

2021
High social jetlag is correlated with nocturnal inhibition of melatonin production among night workers.
    Chronobiology international, 2021, Volume: 38, Issue:8

    Topics: Brazil; Circadian Rhythm; Female; Humans; Hydrocortisone; Jet Lag Syndrome; Melatonin; Pregnancy; Sl

2021
Impact of constant light exposure during pregnancy on skin of neonatal New Zealand rabbits: structural and ultrastructural study.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2021, Volume: 54, Issue:6

    Topics: Animals; Circadian Rhythm; Epidermis; Female; Melatonin; Microscopy, Electron, Transmission; Pregnan

2021
Luffa operculata at a late period of gestation dysregulates melatonin and cytokines interfering with weight of dams and their male offspring.
    Journal of ethnopharmacology, 2021, Jul-15, Volume: 275

    Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Behavior, Animal; Body

2021
Serum Melatonin as a Biomarker for Assessment of Late-term and Postterm Pregnancies in Women without Spontaneous Onset of Labor.
    Zeitschrift fur Geburtshilfe und Neonatologie, 2021, Volume: 225, Issue:6

    Topics: Biomarkers; Female; Gestational Age; Humans; Labor, Obstetric; Melatonin; Pregnancy; Prospective Stu

2021
Melatonin ameliorates hypertension in hypertensive pregnant mice and suppresses the hypertension-induced decrease in Ca
    Hypertension research : official journal of the Japanese Society of Hypertension, 2021, Volume: 44, Issue:9

    Topics: Animals; Female; Hypertension, Pregnancy-Induced; Melatonin; Mice; Placenta; Pregnancy; Pregnancy Ou

2021
Melatonin-MT1 signal is essential for endometrial decidualization.
    Reproduction (Cambridge, England), 2021, 07-12, Volume: 162, Issue:2

    Topics: Abortion, Spontaneous; Adult; Animals; Case-Control Studies; Cells, Cultured; Decidua; Endometrium;

2021
Effect of melatonin supplementation during IVM of dromedary camel oocytes (Camelus dromedarius) on their maturation, fertilization, and developmental rates in vitro.
    Theriogenology, 2021, Sep-15, Volume: 172

    Topics: Animals; Camelus; Dietary Supplements; Female; Fertilization; Fertilization in Vitro; In Vitro Oocyt

2021
Two melatonin treatments improve the conception rate after fixed-time artificial insemination in beef heifers following synchronisation of oestrous cycles using the CoSynch-56 protocol.
    Australian veterinary journal, 2021, Volume: 99, Issue:10

    Topics: Animals; Cattle; Dinoprost; Estrus Synchronization; Female; Gonadotropin-Releasing Hormone; Insemina

2021
Effects of achromatic and chromatic lights on pupillary response, endocrinology, activity, and milk production in dairy cows.
    PloS one, 2021, Volume: 16, Issue:7

    Topics: Animals; Cattle; Circadian Rhythm; Female; Lactation; Light; Lighting; Melatonin; Milk; Pregnancy; P

2021
Melatonin and gestational hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2021, Volume: 44, Issue:11

    Topics: Blood Pressure; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Melatonin; Pregnancy

2021
Melatonin alters bovine uterine artery hemodynamics, vaginal temperatures, and fetal morphometrics during late gestational nutrient restriction in a season-dependent manner.
    Journal of animal science, 2021, Sep-01, Volume: 99, Issue:9

    Topics: Animals; Cattle; Female; Fetus; Hemodynamics; Melatonin; Nutrients; Pregnancy; Seasons; Temperature;

2021
Identification of the blue light intensity administered to one eye required to suppress bovine plasma melatonin and investigation into effects on milk production in grazing dairy cows.
    Journal of dairy science, 2021, Volume: 104, Issue:11

    Topics: Animals; Cattle; Diet; Female; Lactation; Melatonin; Milk; Parity; Photoperiod; Pregnancy

2021
Melatonin, a Potential Therapeutic Agent for Preeclampsia, Reduces the Extrusion of Toxic Extracellular Vesicles from Preeclamptic Placentae.
    Cells, 2021, 07-27, Volume: 10, Issue:8

    Topics: Adult; Cell Line; Endothelial Cells; Extracellular Vesicles; Female; Humans; Intercellular Adhesion

2021
Attempts to improve human ovarian transplantation outcomes of needle-immersed vitrification and slow-freezing by host and graft treatments.
    Journal of assisted reproduction and genetics, 2017, Volume: 34, Issue:5

    Topics: Adult; Animals; Apoptosis; Cell Survival; Cryopreservation; Embryo Implantation; Female; Freezing; H

2017
Prolactin modulates luteal activity in the short-nosed fruit bat, Cynopterus sphinx during delayed embryonic development.
    General and comparative endocrinology, 2017, 07-01, Volume: 248

    Topics: Animals; Body Weight; Chiroptera; Cholesterol; Corpus Luteum; Embryonic Development; Estradiol; Fema

2017
Prenatal Hyperhomocysteinemia Impairs Hypothalamic Regulation of Reproductive Cycles in Rat Progeny.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:6

    Topics: Animals; Antioxidants; Arcuate Nucleus of Hypothalamus; Catecholamines; Estrous Cycle; Female; Gonad

2017
Melatonin Improves Mitochondrial Respiration in Syncytiotrophoblasts From Placentas of Obese Women.
    Reproductive sciences (Thousand Oaks, Calif.), 2018, Volume: 25, Issue:1

    Topics: Adult; Antioxidants; Body Mass Index; Energy Metabolism; Female; Humans; Melatonin; Mitochondria; Ob

2018
Effects of Antenatal Melatonin Treatment on the Cerebral Vasculature in an Ovine Model of Fetal Growth Restriction.
    Developmental neuroscience, 2017, Volume: 39, Issue:1-4

    Topics: Animals; Antioxidants; Brain; Female; Fetal Growth Retardation; Hypoxia-Ischemia, Brain; Melatonin;

2017
The neuroprotective effect of melatonin on the hippocampus exposed to diclofenac sodium during the prenatal period.
    Journal of chemical neuroanatomy, 2018, Volume: 87

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diclofenac; Female; Hippocampus; Mal

2018
Melatonin protects against maternal obesity-associated oxidative stress and meiotic defects in oocytes via the SIRT3-SOD2-dependent pathway.
    Journal of pineal research, 2017, Volume: 63, Issue:3

    Topics: Acetylation; Animals; Antioxidants; Diet, High-Fat; Drug Evaluation, Preclinical; Embryonic Developm

2017
Rapid modulation of the silent information regulator 1 by melatonin after hypoxia-ischemia in the neonatal rat brain.
    Journal of pineal research, 2017, Volume: 63, Issue:3

    Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Death; Female; Glial Fibrillary Acidic Protein; Mela

2017
Maternal photoperiod programs hypothalamic thyroid status via the fetal pituitary gland.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 08-01, Volume: 114, Issue:31

    Topics: Animals; Brain; Circadian Clocks; Circadian Rhythm; Cricetinae; Female; Gene Expression Regulation,

2017
Effects of Melatonin on Early Pregnancy in Mouse: Involving the Regulation of StAR, Cyp11a1, and Ihh Expression.
    International journal of molecular sciences, 2017, Jul-27, Volume: 18, Issue:8

    Topics: Animals; Animals, Newborn; Cholesterol Side-Chain Cleavage Enzyme; Embryo Implantation; Endometrium;

2017
Maternal administration of melatonin exerts short- and long-term neuroprotective effects on the offspring from lipopolysaccharide-treated mice.
    Journal of pineal research, 2017, Volume: 63, Issue:4

    Topics: Animals; Birth Injuries; Brain Injuries; Female; Inflammation; Lipopolysaccharides; Melatonin; Mice;

2017
Effects of antenatal melatonin therapy on lung structure in growth-restricted newborn lambs.
    Journal of applied physiology (Bethesda, Md. : 1985), 2017, Nov-01, Volume: 123, Issue:5

    Topics: Animals; Animals, Newborn; Antioxidants; Female; Fetal Growth Retardation; Lung; Melatonin; Pregnanc

2017
Melatonin prevents preeclamptic sera and antiphospholipid antibodies inducing the production of reactive nitrogen species and extrusion of toxic trophoblastic debris from first trimester placentae.
    Placenta, 2017, Volume: 58

    Topics: Adult; Antibodies, Antiphospholipid; Endothelial Cells; Extracellular Vesicles; Female; Humans; Mela

2017
Maternal melatonin or agomelatine therapy prevents programmed hypertension in male offspring of mother exposed to continuous light.
    Biology of reproduction, 2017, Oct-01, Volume: 97, Issue:4

    Topics: Acetamides; Animals; Antioxidants; Female; Hypertension; Hypnotics and Sedatives; Light; Male; Mater

2017
Comparison of Melatonin Levels in the Colostrum between Vaginal Delivery and Cesarean Delivery.
    American journal of perinatology, 2018, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Cesarean Section; Colostrum; Cross-Sectional Studies; Delivery, Obstetric; Female

2018
Melatonin concentration in follicular fluid is correlated with antral follicle count (AFC) and in vitro fertilization (IVF) outcomes in women undergoing assisted reproductive technology (ART) procedures.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2018, Volume: 34, Issue:5

    Topics: Adult; Anti-Mullerian Hormone; Estradiol; Female; Fertilization in Vitro; Follicle Stimulating Hormo

2018
Melatonin Pharmacokinetics Following Oral Administration in Preterm Neonates.
    Molecules (Basel, Switzerland), 2017, Dec-01, Volume: 22, Issue:12

    Topics: Administration, Oral; Adult; Area Under Curve; Combined Modality Therapy; Dose-Response Relationship

2017
Phase I Pilot Clinical Trial of Antenatal Maternally Administered Melatonin to Decrease the Level of Oxidative Stress in Human Pregnancies Affected by Preeclampsia.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1710

    Topics: Antioxidants; Clinical Trials, Phase I as Topic; Female; Humans; Melatonin; Oxidative Stress; Pilot

2018
A Randomized Double-Blinded Placebo-Controlled Intervention Trial of Melatonin for the Prevention of Preeclampsia in Moderate- and High-Risk Women: The MELPOP Trial.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1710

    Topics: Antioxidants; Double-Blind Method; Female; Humans; Melatonin; Oxidative Stress; Placebo Effect; Pre-

2018
Effects of Melatonin on Blood Pressure, Oxidative Stress and Placental Expressions of TNFα, IL-6, VEGF and sFlt-1 in RUPP Rat Model of Preeclampsia.
    Archives of medical research, 2017, Volume: 48, Issue:7

    Topics: Animals; Biomarkers; Blood Pressure; Female; Interleukin-6; Melatonin; Oxidative Stress; Placenta; P

2017
Low maternal melatonin level increases autism spectrum disorder risk in children.
    Research in developmental disabilities, 2018, Volume: 82

    Topics: Adult; Autism Spectrum Disorder; Case-Control Studies; Child; Female; Gene-Environment Interaction;

2018
Role of Endogenous Melatonin in the Regulation of Th17/Treg Balance during Pregnancy.
    Bulletin of experimental biology and medicine, 2018, Volume: 164, Issue:4

    Topics: Adult; Cell Differentiation; Female; Forkhead Transcription Factors; Gene Expression Regulation; Hum

2018
An open-label pilot study of a home wearable light therapy device for postpartum depression.
    Archives of women's mental health, 2018, Volume: 21, Issue:5

    Topics: Adult; Circadian Rhythm; Depression, Postpartum; Feasibility Studies; Female; Humans; Melatonin; Pho

2018
Therapeutic effect of perinatal exogenous melatonin on behavioral and histopathological changes and antioxidative enzymes in neonate mouse model of cortical malformation.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2018, Volume: 68

    Topics: Animals; Animals, Newborn; Antioxidants; Carcinogens; Catalase; Disease Models, Animal; Exploratory

2018
Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring.
    Molecules (Basel, Switzerland), 2018, Apr-11, Volume: 23, Issue:4

    Topics: Animals; Disease Models, Animal; Female; Fructose; Gene Expression Regulation; Hypertension; Male; M

2018
Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Antioxidants; Female; Gene Expression Regulation; Humans; Melatonin; Placenta; Pre-Eclampsia; Pregna

2018
Human colostrum action against Giardia lamblia infection influenced by hormones and advanced maternal age.
    Parasitology research, 2018, Volume: 117, Issue:6

    Topics: Adolescent; Adult; Aging; Animals; Child; Colostrum; Cross-Sectional Studies; Female; Giardia lambli

2018
The effects of leptin on plasma concentrations of prolactin, growth hormone, and melatonin vary depending on the stage of pregnancy in sheep.
    Journal of animal science, 2018, Jul-28, Volume: 96, Issue:8

    Topics: Animals; Endocrine System; Female; Growth Hormone; Leptin; Melatonin; Pregnancy; Prolactin; Random A

2018
Effects of AANAT overexpression on the inflammatory responses and autophagy activity in the cellular and transgenic animal levels.
    Autophagy, 2018, Volume: 14, Issue:11

    Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Arylalkylamine N-Acetyltransferase; Autoph

2018
Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2018, Volume: 832-833

    Topics: Animals; Animals, Newborn; Brain; Central Nervous System Depressants; Comet Assay; DNA Damage; Ethan

2018
Melatonin supplementation during prolonged in vitro maturation improves the quality and development of poor-quality porcine oocytes via anti-oxidative and anti-apoptotic effects.
    Molecular reproduction and development, 2018, Volume: 85, Issue:8-9

    Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Blastocyst; Cells, Cultured; Cumulus Cells;

2018
The absence of maternal pineal melatonin rhythm during pregnancy and lactation impairs offspring physical growth, neurodevelopment, and behavior.
    Hormones and behavior, 2018, Volume: 105

    Topics: Animals; Behavior, Animal; Circadian Rhythm; Cognition; Female; Growth and Development; Lactation; M

2018
Effect of melatonin on attenuating the isoflurane-induced oxidative damage is related to PKCα/Nrf2 signaling pathway in developing rats.
    Brain research bulletin, 2018, Volume: 143

    Topics: Animals; Antioxidants; Female; Glutathione; Hippocampus; Isoflurane; Male; Malondialdehyde; Melatoni

2018
Effects of subcutaneous melatonin implants and short-term intravaginal progestagen treatments on estrus induction and fertility of Kivircik ewes on seasonal anestrus.
    Polish journal of veterinary sciences, 2018, Volume: 21, Issue:2

    Topics: Anestrus; Animals; Estrus; Female; Fertility; Male; Melatonin; Pregnancy; Progesterone; Progestins;

2018
Potential effects and molecular mechanisms of melatonin on the dopaminergic neuronal differentiation of human amniotic fluid mesenchymal stem cells.
    Neurochemistry international, 2019, Volume: 124

    Topics: Amniotic Fluid; Antioxidants; Cell Differentiation; Cell Survival; Cells, Cultured; Dopaminergic Neu

2019
Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Apoptosis; Autophagy; Cell Line, Tumor; Choriocarcinoma; Female; Humans; Melatonin; Neoplasm Protein

2019
Genotype of MTNR1A gene regulates the conception rate following melatonin treatment in water buffalo.
    Theriogenology, 2019, Apr-01, Volume: 128

    Topics: Animals; Buffaloes; Female; Fertilization; Genotype; Melatonin; Polymorphism, Genetic; Pregnancy; Pr

2019
Photoperiod-treated bucks are equal to melatonin-treated bucks for inducing reproductive behaviour and physiological functions via the "male effect" in Mediterranean goats.
    Animal reproduction science, 2019, Volume: 202

    Topics: Animals; Antioxidants; Female; Goats; Male; Melatonin; Ovulation; Photoperiod; Pregnancy; Progestero

2019
Relationship between endogenous melatonin concentrations and uterine contractions in late third trimester of human pregnancy.
    Journal of pineal research, 2019, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Circadian Rhythm; Female; Humans; Melatonin; Pregnancy; Pregnancy Trimester, Thir

2019
Shift work and pregnancy: night light, baby not right.
    The Journal of physiology, 2019, Volume: 597, Issue:7

    Topics: Animals; Circadian Rhythm; Melatonin; Pregnancy; Sheep; Shift Work Schedule; Sleep

2019
Antenatal melatonin modulates an enhanced antioxidant/pro-oxidant ratio in pulmonary hypertensive newborn sheep.
    Redox biology, 2019, Volume: 22

    Topics: Animals; Animals, Newborn; Antioxidants; Biomarkers; Birth Weight; Blood Gas Analysis; Female; Gene

2019
The Role of Melatonin in Oxidative Stress, DNA Damage, Apoptosis and Angiogenesis in Fetal Eye under Preeclampsia and Melatonin Deficiency Stress.
    Current eye research, 2019, Volume: 44, Issue:10

    Topics: Animals; Apoptosis; Aryl Hydrocarbon Receptor Nuclear Translocator; Blotting, Western; DNA Damage; E

2019
Administration of melatonin for prevention of preterm birth and fetal brain injury associated with premature birth in a mouse model.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2019, Volume: 82, Issue:3

    Topics: Animals; Brain Injuries; Disease Models, Animal; Female; Fetal Diseases; Hemodynamics; Humans; Immun

2019
Melatonin for prevention of placental malperfusion and fetal compromise associated with intrauterine inflammation-induced oxidative stress in a mouse model.
    Journal of pineal research, 2019, Volume: 67, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Hemodynamics; Inflammation; Lipopolysaccharides; Melatonin;

2019
Maternal exposure to environmentally relevant doses of bisphenol A causes reproductive dysfunction in F1 adult male rats: protective role of melatonin.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:28

    Topics: Animals; Antioxidants; Benzhydryl Compounds; Estradiol; Female; Follicle Stimulating Hormone; Hydrog

2019
The foetal pig pineal gland is richly innervated by nerve fibres containing catecholamine-synthesizing enzymes, neuropeptide Y (NPY) and C-terminal flanking peptide of NPY, but it does not secrete melatonin.
    Histology and histopathology, 2013, Volume: 28, Issue:5

    Topics: Animals; Catecholamines; Dopamine beta-Hydroxylase; Female; Fetus; Fluorescent Antibody Technique; M

2013
Influence of the male effect on the reproductive performance of female Payoya goats implanted with melatonin at the winter solstice.
    Animal reproduction science, 2013, Volume: 137, Issue:3-4

    Topics: Animals; Corpus Luteum; Estrous Cycle; Female; Goats; Male; Melatonin; Pregnancy; Progesterone; Repr

2013
Mechanisms of melatonin-induced protection in the brain of late gestation fetal sheep in response to hypoxia.
    Developmental neuroscience, 2012, Volume: 34, Issue:6

    Topics: Animals; Brain; Disease Models, Animal; Female; Fetal Hypoxia; Fetus; Hypoxia, Brain; Immunohistoche

2012
Antioxidant effect of melatonin on the functional activity of colostral phagocytes in diabetic women.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Antioxidants; Calcium; Colostrum; Cross-Sectional Studies; Escherichia coli; Fema

2013
Impact of chronodisruption during primate pregnancy on the maternal and newborn temperature rhythms.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animals; Animals, Newborn; Behavior, Animal; Cebus; Circadian Rhythm; Female; Light; Male; Maternal

2013
Evaluation of melatonin and prostaglandin E1 combination on necrotizing enterocolitis model in neonatal rats.
    Regulatory peptides, 2013, Jun-10, Volume: 184

    Topics: Alprostadil; Animals; Animals, Newborn; Drug Therapy, Combination; Enterocolitis, Necrotizing; Femal

2013
Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats.
    Sheng li xue bao : [Acta physiologica Sinica], 2013, Apr-25, Volume: 65, Issue:2

    Topics: Animals; Body Weight; Female; Litter Size; Melatonin; Pregnancy; Pregnancy Outcome; Pregnancy, Anima

2013
Circadian phase shifts and mood across the perinatal period in women with a history of major depressive disorder: a preliminary communication.
    Journal of affective disorders, 2013, Sep-25, Volume: 150, Issue:3

    Topics: Actigraphy; Adult; Affect; Circadian Rhythm; Depressive Disorder, Major; Female; Humans; Light; Mela

2013
Increase of placental sensitivity to melatonin and the alteration to its local synthesis in hypertensive syndromes in pregnancy.
    Hypertension in pregnancy, 2013, Volume: 32, Issue:2

    Topics: Female; Humans; Hypertension, Pregnancy-Induced; Melatonin; Placenta; Pregnancy; Receptor, Melatonin

2013
Dietary melatonin supplementation alters uteroplacental amino acid flux during intrauterine growth restriction in ewes.
    Animal : an international journal of animal bioscience, 2013, Volume: 7, Issue:9

    Topics: Amino Acids; Animals; Blood Glucose; Chromatography, High Pressure Liquid; Dietary Supplements; Fema

2013
Melatonin promotes the in vitro development of pronuclear embryos and increases the efficiency of blastocyst implantation in murine.
    Journal of pineal research, 2013, Volume: 55, Issue:3

    Topics: Animals; Antioxidants; Blastocyst; Caspase 3; Embryo Implantation; Female; Gene Expression Regulatio

2013
Uterine infusion of melatonin or melatonin receptor antagonist alters ovine feto-placental hemodynamics during midgestation.
    Biology of reproduction, 2013, Volume: 89, Issue:2

    Topics: Animals; Female; Fetus; Hemodynamics; Melatonin; Placenta; Pregnancy; Receptors, Melatonin; Regional

2013
Effects of melatonin on superovulation and transgenic embryo transplantation in small-tailed han sheep (Ovis aries).
    Neuro endocrinology letters, 2013, Volume: 34, Issue:4

    Topics: Animals; Animals, Genetically Modified; Antioxidants; Corpus Luteum; Embryo Implantation; Embryo Tra

2013
Antepartum depression severity is increased during seasonally longer nights: relationship to melatonin and cortisol timing and quantity.
    Chronobiology international, 2013, Volume: 30, Issue:9

    Topics: Adult; Affect; Area Under Curve; Circadian Rhythm; Cross-Sectional Studies; Darkness; Depression; Fe

2013
Partial neural protection with prophylactic low-dose melatonin after asphyxia in preterm fetal sheep.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:1

    Topics: Animals; Asphyxia Neonatorum; Brain; Dose-Response Relationship, Drug; Drug Carriers; Ethanol; Femal

2014
Melatonin prevents experimental preterm labor and increases offspring survival.
    Journal of pineal research, 2014, Volume: 56, Issue:2

    Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Female; Lipopolysaccharides; Melatonin; Mice; Mic

2014
Neuroendocrine and genetic control of seasonal reproduction in sheep and goats.
    Reproduction in domestic animals = Zuchthygiene, 2010, Volume: 45 Suppl 3

    Topics: Animals; Breeding; Female; Genetic Variation; Goats; Gonadotropin-Releasing Hormone; Lactation; Male

2010
Melatonin treatment during early life interacts with restraint to alter neuronal morphology and provoke depressive-like responses.
    Behavioural brain research, 2014, Apr-15, Volume: 263

    Topics: Anhedonia; Animals; Anxiety; CA1 Region, Hippocampal; Cricetinae; Dendrites; Depressive Disorder; Di

2014
Persistence of fertility despite semen alterations in a pinealectomised patient treated with melatonin.
    Neuro endocrinology letters, 2013, Volume: 34, Issue:8

    Topics: Adult; Central Nervous System Depressants; Female; Fertility; Humans; Male; Melatonin; Pineal Gland;

2013
Similar photoperiod-related birth seasonalities among professional baseball players and lesbian women with an opposite seasonality among gay men: Maternal melatonin may affect fetal sexual dimorphism.
    Psychiatry research, 2014, May-30, Volume: 216, Issue:3

    Topics: Age Factors; Athletes; Baseball; Brain; Europe; Female; Fetus; Gestational Age; Homosexuality, Femal

2014
Melatonin ameliorates brain injury induced by systemic lipopolysaccharide in neonatal rats.
    Neuroscience, 2014, May-16, Volume: 267

    Topics: Aldehydes; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Antioxidants; Brain Injuries;

2014
Gestational chronodisruption impairs hippocampal expression of NMDA receptor subunits Grin1b/Grin3a and spatial memory in the adult offspring.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Circadian Clocks; Female; Gene Expression Regulation; Hippocampus; Light; Maternal Exposure

2014
Maternal melatonin administration mitigates coronary stiffness and endothelial dysfunction, and improves heart resilience to insult in growth restricted lambs.
    The Journal of physiology, 2014, Jun-15, Volume: 592, Issue:12

    Topics: Animals; Cardiotonic Agents; Coronary Circulation; Endothelium, Vascular; Female; Fetal Growth Retar

2014
Melatonin attenuates prenatal dexamethasone-induced blood pressure increase in a rat model.
    Journal of the American Society of Hypertension : JASH, 2014, Volume: 8, Issue:4

    Topics: Animals; Blotting, Western; Dexamethasone; Female; Histone Deacetylases; Hypertension; Maternal Expo

2014
Effect of maternal nutrient restriction and melatonin supplementation from mid to late gestation on vascular reactivity of maternal and fetal placental arteries.
    Placenta, 2014, Volume: 35, Issue:7

    Topics: Angiotensin II; Animal Nutritional Physiological Phenomena; Animals; Bradykinin; Diet; Female; Mater

2014
Melatonin in the regulation of liver steatosis following prenatal glucocorticoid exposure.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Apoptosis; Cytokines; Fatty Liver; Female; Glucocorticoids; Liver; Male; Melatonin; Pregnan

2014
Melatonin therapy prevents programmed hypertension and nitric oxide deficiency in offspring exposed to maternal caloric restriction.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Animals; Arginine; Caloric Restriction; Female; Hypertension; In Vitro Techniques; Kidney; Male; Mel

2014
Melatonin prevents maternal fructose intake-induced programmed hypertension in the offspring: roles of nitric oxide and arachidonic acid metabolites.
    Journal of pineal research, 2014, Volume: 57, Issue:1

    Topics: Animals; Arachidonic Acid; Blood Pressure; Chromatography, High Pressure Liquid; Electron Spin Reson

2014
Effect of the combination of metformin hydrochloride and melatonin on oxidative stress before and during pregnancy, and biochemical and histopathological analysis of the livers of rats after treatment for polycystic ovary syndrome.
    Toxicology and applied pharmacology, 2014, Oct-01, Volume: 280, Issue:1

    Topics: Animals; Antioxidants; Drug Therapy, Combination; Female; Liver; Melatonin; Metformin; Oxidative Str

2014
Melatonin secretion is impaired in women with preeclampsia and an abnormal circadian blood pressure rhythm.
    Renal failure, 2014, Volume: 36, Issue:7

    Topics: Adult; Blood Pressure; Case-Control Studies; Circadian Rhythm; Female; Humans; Melatonin; Postpartum

2014
Introduction: circadian rhythm and its disruption: impact on reproductive function.
    Fertility and sterility, 2014, Volume: 102, Issue:2

    Topics: Animals; Circadian Clocks; Circadian Rhythm; Female; Humans; Hydrocortisone; Light; Male; Melatonin;

2014
Melatonin as potential inducer of Th17 cell differentiation.
    Medical hypotheses, 2014, Volume: 83, Issue:3

    Topics: Autoimmune Diseases; Cell Differentiation; Disease Progression; Female; Humans; Immune System; Inter

2014
A pilot study to search possible mechanisms of ultralong gonadotropin-releasing hormone agonist therapy in IVF-ET patients with endometriosis.
    Journal of ovarian research, 2014, Oct-21, Volume: 7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Biomarkers; Deoxyguanosine; Endometriosis; Female; Fertilization

2014
Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats.
    Journal of lipid research, 2015, Volume: 56, Issue:1

    Topics: Animals; Behavior, Animal; Biomarkers; Body Weight; Brain; Brain-Derived Neurotrophic Factor; Depres

2015
Orally administered melatonin prevents lipopolysaccharide-induced neural tube defects in mice.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Administration, Oral; Anencephaly; Animals; Antioxidants; Chemokines; Female; Folic Acid; Gene Expre

2014
Can the season of birth risk factor for schizophrenia be prevented by bright light treatment for the second trimester mother around the winter solstice?
    Medical hypotheses, 2014, Volume: 83, Issue:6

    Topics: Body Temperature; Circadian Rhythm; Corpus Striatum; Female; Hippocampus; Humans; Light; Maternal Ex

2014
Evaluation of neuroprotection by melatonin against adverse effects of prenatal exposure to a nonsteroidal anti-inflammatory drug during peripheral nerve development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015, Volume: 41

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroida

2015
Antioxidative status and oxidative stress in the fetal circulation at birth: the effects of time of delivery and presence of labor.
    Early human development, 2015, Volume: 91, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Deoxyguanosine; Female; Fetal Blood; Glutathione Peroxidase; Hum

2015
Effects of melatonin on prenatal dexamethasone-induced epigenetic alterations in hippocampal morphology and reelin and glutamic acid decarboxylase 67 levels.
    Developmental neuroscience, 2015, Volume: 37, Issue:2

    Topics: Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Dexamethasone; DNA (Cytosine-5-)-Methy

2015
Melatonin prevents oxidative damage induced by maternal ethanol administration and reduces homocysteine in the cerebellum of rat pups.
    Behavioural brain research, 2015, Volume: 287

    Topics: Animals; bcl-2-Associated X Protein; Catalase; Central Nervous System Depressants; Cerebellum; Ethan

2015
Placental melatonin system is present throughout pregnancy and regulates villous trophoblast differentiation.
    Journal of pineal research, 2015, Volume: 59, Issue:1

    Topics: Acetylserotonin O-Methyltransferase; Arylalkylamine N-Acetyltransferase; Cell Differentiation; Cells

2015
Melatonin inhibits embryonic salivary gland branching morphogenesis by regulating both epithelial cell adhesion and morphology.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Animals; Apoptosis; Cell Adhesion; Cell Shape; Embryonic Development; Epithelial Cells; Female; Gene

2015
Melatonin modulates the fetal cardiovascular defense response to acute hypoxia.
    Journal of pineal research, 2015, Volume: 59, Issue:1

    Topics: Animals; Catecholamines; Female; Fetus; Hypoxia; Melatonin; Nitric Oxide; Oxidative Stress; Pregnanc

2015
Melatonin Ameliorates Arsenite-Induced Neurotoxicity: Involvement of Autophagy and Mitochondria.
    Molecular neurobiology, 2015, Volume: 52, Issue:2

    Topics: Adenine; alpha-Synuclein; Animals; Antioxidants; Arsenites; Autophagy; Biomarkers; Cells, Cultured;

2015
Xanthohumol impairs glucose uptake by a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) and impacts the process of placentation.
    Molecular human reproduction, 2015, Volume: 21, Issue:10

    Topics: Biological Transport; Cell Division; Cell Line, Transformed; Cell Movement; Cytochalasin B; Deoxyglu

2015
Melatonin ameliorates oxidative damage induced by maternal lead exposure in rat pups.
    Physiology & behavior, 2015, Nov-01, Volume: 151

    Topics: Animals; Cerebellum; Female; Glutathione Peroxidase; Lead; Lipid Peroxidation; Maternal Exposure; Me

2015
Melatonin treatment in spring and reproductive recovery in sheep with different body condition score and age.
    Animal reproduction science, 2015, Volume: 160

    Topics: Aging; Animals; Body Composition; Female; Melatonin; Pregnancy; Reproduction; Seasons; Sheep

2015
Cold stress protein RBM3 responds to temperature change in an ultra-sensitive manner in young neurons.
    Neuroscience, 2015, Oct-01, Volume: 305

    Topics: Analysis of Variance; Animals; Antioxidants; Astrocytes; Cells, Cultured; Cerebral Cortex; Embryo, M

2015
Effects of melatonin on diclofenac sodium treated rat kidney: a stereological and histopathological study.
    Renal failure, 2015, Volume: 37, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diclofenac; Female; Kidney Glomerulu

2015
Melatonin rescues cardiovascular dysfunction during hypoxic development in the chick embryo.
    Journal of pineal research, 2016, Volume: 60, Issue:1

    Topics: Animals; Chick Embryo; Disease Models, Animal; Female; Fetal Growth Retardation; Humans; Melatonin;

2016
Melatonin prevents neural tube defects in the offspring of diabetic pregnancy.
    Journal of pineal research, 2015, Volume: 59, Issue:4

    Topics: Animals; Cell Proliferation; Diabetes Mellitus, Experimental; Female; Hyperglycemia; Melatonin; Mice

2015
Molecular characterization and expression profile of the melatonin receptor MT1 in the ovary of Tianzhu white yak (Bos grunniens).
    General and comparative endocrinology, 2017, 02-01, Volume: 242

    Topics: Amino Acid Sequence; Animals; Cattle; DNA, Complementary; Female; Gene Expression Regulation; Granul

2017
[The influence of interfered circadian rhythm on pregnancy and neonatal rats].
    Sheng li xue bao : [Acta physiologica Sinica], 2015, Oct-25, Volume: 67, Issue:5

    Topics: Animals; Circadian Rhythm; Female; Light; Melatonin; Pregnancy; Pregnancy, Animal; Progesterone; Rat

2015
No improvement of neuronal metabolism in the reperfusion phase with melatonin treatment after hypoxic-ischemic brain injury in the neonatal rat.
    Journal of neurochemistry, 2016, Volume: 136, Issue:2

    Topics: Acetates; Animals; Animals, Newborn; Antioxidants; Astrocytes; Brain Injuries; Brain Ischemia; Disea

2016
Supplementation of Slow-Release Melatonin Improves Recovery of Ovarian Cyclicity and Conception in Summer Anoestrous Buffaloes (Bubalus bubalis).
    Reproduction in domestic animals = Zuchthygiene, 2016, Volume: 51, Issue:1

    Topics: Anestrus; Animals; Buffaloes; Delayed-Action Preparations; Estrous Cycle; Female; Fertilization; Ins

2016
Salivary melatonin levels and sleep-wake rhythms in pregnant women with hypertensive and glucose metabolic disorders: A prospective analysis.
    Bioscience trends, 2016, Volume: 10, Issue:1

    Topics: Adult; Circadian Rhythm; Demography; Female; Glucose; Humans; Hypertension, Pregnancy-Induced; Melat

2016
Potential adverse effects of antenatal melatonin as a treatment for intrauterine growth restriction: findings in pregnant sheep.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:2

    Topics: Animals; Biomarkers; Birth Weight; Female; Fetal Development; Fetal Growth Retardation; Gestational

2016
Postnatal dexamethasone-induced programmed hypertension is related to the regulation of melatonin and its receptors.
    Steroids, 2016, Volume: 108

    Topics: Animals; Blood Pressure; Dexamethasone; Female; Gene Expression Regulation; Heart; Hypertension; Kid

2016
The effects of melatonin on endometriotic lesions induced by implanting human endometriotic cells in the first SCID-mouse endometriosis-model developed in Turkey.
    Clinical and experimental obstetrics & gynecology, 2016, Volume: 43, Issue:1

    Topics: Animals; Antioxidants; Disease Models, Animal; Endometriosis; Estradiol; Female; Melatonin; Mice; Mi

2016
Evaluation of two commercially available ELISA kits for the determination of melatonin concentrations in amniotic fluid throughout pregnancy.
    Annals of clinical biochemistry, 2017, Volume: 54, Issue:1

    Topics: Adult; Amniotic Fluid; Enzyme-Linked Immunosorbent Assay; Female; Gestational Age; Humans; Liquid-Li

2017
The reduction in circulating levels of melatonin may be associated with the development of preeclampsia.
    Journal of human hypertension, 2016, Volume: 30, Issue:11

    Topics: Biomarkers; China; Down-Regulation; Female; Hospitals, Teaching; Humans; Incidence; Melatonin; Place

2016
The impaired myocardial ischemic tolerance in adult offspring of diabetic pregnancy is restored by maternal melatonin treatment.
    Journal of pineal research, 2016, Volume: 61, Issue:3

    Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Dietary Supplements; Female; Melatonin; Mice; M

2016
Effects of Two Types of Melatonin-Loaded Nanocapsules with Distinct Supramolecular Structures: Polymeric (NC) and Lipid-Core Nanocapsules (LNC) on Bovine Embryo Culture Model.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catalase; Cattle; Culture M

2016
Presence and concentration of 17 hormones in human placenta processed for encapsulation and consumption.
    Placenta, 2016, Volume: 43

    Topics: Adult; Chromatography, Liquid; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Melatonin;

2016
Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway.
    Journal of pineal research, 2016, Volume: 61, Issue:3

    Topics: Animals; Animals, Newborn; Autophagy; Brain; Endoplasmic Reticulum Stress; Female; Inflammation; Lip

2016
Neuroprotective effects of melatonin and omega-3 on hippocampal cells prenatally exposed to 900 MHz electromagnetic fields.
    International journal of radiation biology, 2016, Volume: 92, Issue:10

    Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electromagnetic Fi

2016
Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Biomarkers; Female; Fetal Development;

2016
Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption.
    Journal of visualized experiments : JoVE, 2016, 07-30, Issue:113

    Topics: Apoptosis; Cell Hypoxia; Cells, Cultured; Female; Humans; Melatonin; Placenta; Pregnancy; Trophoblas

2016
Extended Culture of Encapsulated Human Blastocysts in Alginate Hydrogel Containing Decidualized Endometrial Stromal Cells in the Presence of Melatonin.
    Molecular biotechnology, 2016, Volume: 58, Issue:10

    Topics: Adult; Alginates; Blastocyst; Coculture Techniques; Culture Media; Embryo Culture Techniques; Embryo

2016
Behavioral and molecular effects of prenatal continuous light exposure in the adult rat.
    Brain research, 2016, 11-01, Volume: 1650

    Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain; Circadian Rhythm; Female; Light; Male;

2016
Maternal plasma antioxidant status in the first trimester of pregnancy and development of obstetric complications.
    Placenta, 2016, Volume: 47

    Topics: Adult; Biomarkers; Catalase; Diet; Female; Glutathione; Glutathione Peroxidase; Humans; Malondialdeh

2016
Gestational Chronodisruption Impairs Circadian Physiology in Rat Male Offspring, Increasing the Risk of Chronic Disease.
    Endocrinology, 2016, Volume: 157, Issue:12

    Topics: Aldosterone; Animals; Blood Pressure; Body Temperature; Chronic Disease; Circadian Rhythm; CLOCK Pro

2016
Melatonin levels in follicular fluid as markers for IVF outcomes and predicting ovarian reserve.
    Reproduction (Cambridge, England), 2017, Volume: 153, Issue:4

    Topics: Adult; Biomarkers; Female; Fertilization in Vitro; Follicular Fluid; Humans; Melatonin; Middle Aged;

2017
Effects of melatonin in rats in the initial third stage of pregnancy exposed to sub-lethal doses of herbicides.
    Acta histochemica, 2017, Volume: 119, Issue:3

    Topics: Animals; Body Weight; Environmental Exposure; Female; Glycine; Glyphosate; Herbicides; Lipid Peroxid

2017
Maternal administration of melatonin prevents spatial learning and memory deficits induced by developmental ethanol and lead co-exposure.
    Physiology & behavior, 2017, 05-01, Volume: 173

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Catalase; Drug Administr

2017
Effect of exogenous melatonin treatment on the reproductive characteristics and progeny of male rats exposed to different periods from light and darkness.
    Physiological research, 2017, 07-18, Volume: 66, Issue:3

    Topics: Animals; Animals, Newborn; Darkness; Female; Light; Male; Melatonin; Organ Size; Photoperiod; Pregna

2017
The protective effect of melatonin on nicotine-induced myocardial injury in newborn rats whose mothers received nicotine.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2008, Volume: 8, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Dose-Response Relationship, Drug; Female; Glutathione Perox

2008
Melatonin treatment prior to the normal breeding season increases fetal number in United Kingdom sheep flocks.
    Veterinary journal (London, England : 1997), 2009, Volume: 182, Issue:2

    Topics: Animals; Breeding; Delayed-Action Preparations; Female; Litter Size; Male; Melatonin; Pregnancy; Ran

2009
Plasma melatonin circadian rhythm disturbances during pregnancy and postpartum in depressed women and women with personal or family histories of depression.
    The American journal of psychiatry, 2008, Volume: 165, Issue:12

    Topics: Adult; Breast Feeding; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disor

2008
Effects of melatonin implants during non-breeding season on sperm motility and reproductive parameters in Rasa Aragonesa rams.
    Reproduction in domestic animals = Zuchthygiene, 2010, Volume: 45, Issue:3

    Topics: Animals; Breeding; Drug Implants; Female; Fertility; Insemination, Artificial; Litter Size; Male; Me

2010
Melatonin synergizes with oxytocin to enhance contractility of human myometrial smooth muscle cells.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:2

    Topics: Cells, Cultured; Connexin 43; Drug Synergism; Female; Gene Expression Regulation; Humans; Labor, Obs

2009
Maternal cell phone use and behavioral problems in children.
    Epidemiology (Cambridge, Mass.), 2009, Volume: 20, Issue:2

    Topics: Cell Phone; Child Behavior; Child, Preschool; Female; Fetal Development; Humans; Melatonin; Mental D

2009
Melatonin attenuates methamphetamine-induced reduction of tyrosine hydroxylase, synaptophysin and growth-associated protein-43 levels in the neonatal rat brain.
    Neurochemistry international, 2009, Volume: 55, Issue:6

    Topics: Amphetamine-Related Disorders; Animals; Animals, Newborn; Antioxidants; Brain; Brain Chemistry; Cent

2009
Effects of CIDR-G and melatonin implants, and their combination on the efficacy of oestrus induction and fertility of Kilis goats.
    Reproduction in domestic animals = Zuchthygiene, 2009, Volume: 44, Issue:4

    Topics: Administration, Intravaginal; Animals; Breeding; Chorionic Gonadotropin; Drug Implants; Estrus; Fema

2009
Effects of annual rainfall and farm on lamb production after treatment with melatonin implants in Merino sheep: a 4-year study.
    New Zealand veterinary journal, 2009, Volume: 57, Issue:3

    Topics: Animal Husbandry; Animals; Case-Control Studies; Drug Implants; Estrus; Female; Logistic Models; Mal

2009
Sleep complaints: Whenever possible, avoid the use of sleeping pills.
    Prescrire international, 2008, Volume: 17, Issue:97

    Topics: Acupuncture Therapy; Adult; Aged; Behavior Therapy; Benzodiazepines; Clinical Trials as Topic; Conge

2008
Antioxidant neuroprotection against ethanol-induced apoptosis in HN2-5 cells.
    Brain research, 2009, Aug-18, Volume: 1285

    Topics: Acetylcysteine; Alcohol-Induced Disorders, Nervous System; Animals; Antioxidants; Apoptosis; Apoptos

2009
Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy.
    Journal of pineal research, 2009, Volume: 46, Issue:4

    Topics: Analysis of Variance; Animals; Birth Weight; Catalase; Female; Fetus; Glutathione Peroxidase; Glutat

2009
Recent trends in hypertension treatment: perspectives from animal studies.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2009, Volume: 27, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Female; Hu

2009
Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomys cahirinus).
    Developmental neuroscience, 2009, Volume: 31, Issue:5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspase 3; Cell Count; Cerebral Cortex;

2009
Melatonin regulates delayed embryonic development in the short-nosed fruit bat, Cynopterus sphinx.
    Reproduction (Cambridge, England), 2009, Volume: 138, Issue:6

    Topics: Animals; Cells, Cultured; Chiroptera; Circadian Rhythm; Embryo, Mammalian; Embryonic Development; Fe

2009
The weight gain response to stress during adulthood is conditioned by both sex and prenatal stress exposure.
    Psychoneuroendocrinology, 2010, Volume: 35, Issue:3

    Topics: Age Factors; Animals; Blood Glucose; Castration; Corticosterone; Eating; Female; Hormones; Male; Mel

2010
Evaluation of management variables to advance conception and calving date of red deer (Cervus elaphus) in New Zealand venison production systems.
    Animal reproduction science, 2010, Volume: 118, Issue:2-4

    Topics: Agriculture; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Breeding; Deer; Diet;

2010
Antioxidant activity of tryptophan in rats under experimental endotoxic shock.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:1

    Topics: Animals; Animals, Suckling; Antioxidants; Cytokines; Dietary Supplements; Disease Models, Animal; Fe

2010
Therapeutic effects of maternal melatonin administration on ischemia/reperfusion-induced oxidative cerebral damage in neonatal rats.
    Neonatology, 2010, Volume: 98, Issue:1

    Topics: Animals; Animals, Newborn; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Female;

2010
Morphological and morphometric changes of pituitary lactotrophs of viscacha (Lagostomus maximus maximus) in relation to reproductive cycle, age, and sex.
    Anatomical record (Hoboken, N.J. : 2007), 2010, Volume: 293, Issue:1

    Topics: Age Factors; Animals; Castration; Female; Immunoenzyme Techniques; Lactotrophs; Male; Melatonin; Pit

2010
Effects of melatonin on in vitro development of mouse two-cell embryos cultured in HTF medium.
    Endocrine research, 2010, Volume: 35, Issue:1

    Topics: Animals; Blastocyst; Culture Media; Dose-Response Relationship, Drug; Embryo Culture Techniques; Emb

2010
The effect of pregnant and oestrous females on male testosterone and behaviour in the tammar wallaby.
    Hormones and behavior, 2010, Volume: 58, Issue:3

    Topics: Animals; Estrus; Female; Macropodidae; Male; Mating Preference, Animal; Melatonin; Odorants; Pregnan

2010
Neonatal arthritis disturbs sleep and behaviour of adult rat offspring and their dams.
    European journal of pain (London, England), 2010, Volume: 14, Issue:10

    Topics: Animals; Animals, Newborn; Antigens, Bacterial; Anxiety; Arthritis, Experimental; Behavior, Animal;

2010
Investigation of maternal melatonin effect on the hippocampal formation of newborn rat model of intrauterine cortical dysplasia.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:11

    Topics: Animals; Animals, Newborn; Antineoplastic Agents, Alkylating; Carmustine; Female; Glial Fibrillary A

2010
Melatonin enhances antioxidant action of alpha-tocopherol and ascorbate against NADPH- and iron-dependent lipid peroxidation in human placental mitochondria.
    Journal of pineal research, 2010, Volume: 49, Issue:2

    Topics: alpha-Tocopherol; Analysis of Variance; Antioxidants; Ascorbic Acid; Drug Synergism; Female; Ferric

2010
Effects of exogenous melatonin on in vivo embryo viability and oocyte competence of undernourished ewes after weaning during the seasonal anestrus.
    Theriogenology, 2010, Sep-01, Volume: 74, Issue:4

    Topics: Anestrus; Animals; Body Weight; Embryo, Mammalian; Embryonic Development; Female; Malnutrition; Mela

2010
Accelerated lambing achieved by a photoperiod regimen consisting of alternating 4-month sequences of long and short days applied year-round.
    Journal of animal science, 2010, Volume: 88, Issue:10

    Topics: Animal Husbandry; Animals; Female; Male; Melatonin; Parity; Photoperiod; Pregnancy; Progesterone; Re

2010
The role of melatonin in post-partum psychosis and depression associated with bipolar disorder.
    Journal of perinatal medicine, 2010, Volume: 38, Issue:6

    Topics: Animals; Bipolar Disorder; Depression, Postpartum; Female; Humans; Melatonin; Models, Animal; Pregna

2010
Effect of genotype at the MTNR1A locus and melatonin treatment on first conception in Sarda ewe lambs.
    Theriogenology, 2010, Volume: 74, Issue:9

    Topics: Animals; Antioxidants; Circadian Rhythm; Female; Genotype; Melatonin; Polymorphism, Single Nucleotid

2010
Protective effect of maternal prenatal melatonin administration on rat pups born to mothers submitted to constant light during gestation.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2010, Volume: 43, Issue:9

    Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Circadian Rhythm; Female; Hydro-Lyases; Malate

2010
Prenatal corticosteroids: pretermer outcomes, stress, schizophrenia, multiple sclerosis and the developmental role of melatonin and vitamin D3.
    Journal of pediatric and adolescent gynecology, 2010, Volume: 23, Issue:5

    Topics: Cholecalciferol; Dietary Supplements; Female; Humans; Hydrocortisone; Infant, Newborn; Melatonin; Mu

2010
Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms.
    Journal of pineal research, 2010, Volume: 49, Issue:4

    Topics: Analysis of Variance; Animals; Ascorbic Acid; Catheters, Indwelling; Female; Fetal Blood; Fetus; Hem

2010
Possible neuroprotective effects of magnesium sulfate and melatonin as both pre- and post-treatment in a neonatal hypoxic-ischemic rat model.
    Neonatology, 2011, Volume: 99, Issue:4

    Topics: Algorithms; Animals; Animals, Newborn; Disease Models, Animal; Drug Administration Schedule; Drug Co

2011
Effects of antenatal, postpartum and post-weaning melatonin supplementation on blood pressure and renal antioxidant enzyme activities in spontaneously hypertensive rats.
    Journal of physiology and biochemistry, 2011, Volume: 67, Issue:2

    Topics: Animals; Antioxidants; Blood Pressure; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1;

2011
Selenium-vitamin E combination and melatonin modulates diabetes-induced blood oxidative damage and fetal outcomes in pregnant rats.
    Biological trace element research, 2011, Volume: 143, Issue:2

    Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Drug Combinations; Female; Glutath

2011
Seasonal variations of Substance P in the striatum of the female rat are affected by maternal and offspring pinealectomy.
    Neuroscience letters, 2011, Apr-01, Volume: 492, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Corpus Striatum; Female; Gene Expression Regulation; Male; M

2011
Adverse effects of melatonin on rat pups of Wistar-Kyoto dams receiving melatonin supplementation during pregnancy.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:7-8

    Topics: Administration, Oral; Animals; Animals, Newborn; Blood Pressure; Female; Maternal Exposure; Melatoni

2012
Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice.
    Journal of pineal research, 2011, Volume: 50, Issue:4

    Topics: Animals; Antioxidants; Blotting, Western; Endoplasmic Reticulum Chaperone BiP; Female; In Vitro Tech

2011
A circadian clock entrained by melatonin is ticking in the rat fetal adrenal.
    Endocrinology, 2011, Volume: 152, Issue:5

    Topics: Adrenal Glands; Analysis of Variance; Animals; ARNTL Transcription Factors; Circadian Clocks; Circad

2011
Growth assessment of diabetic rat fetuses under the influence of insulin and melatonin: a morphologic study.
    Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur, 2010, Volume: 68, Issue:2

    Topics: Animals; Crown-Rump Length; Diabetes Mellitus, Experimental; Female; Fetal Development; Fetal Macros

2010
Bimodal rhythms of general conceptions and the birth-month phenomenon in schizophrenia, neural tube defects, and laterality: a solstitial hypothesis.
    Birth defects research. Part A, Clinical and molecular teratology, 2011, Volume: 91, Issue:4

    Topics: Antioxidants; Embryo Implantation; Epigenomics; Female; Functional Laterality; Humans; Melatonin; Ne

2011
Naughty melatonin: how mothers tick off their fetus.
    Endocrinology, 2011, Volume: 152, Issue:5

    Topics: Adrenal Glands; Animals; ARNTL Transcription Factors; Circadian Clocks; Circadian Rhythm; Corticoste

2011
The effects of cyclophosphamide, melatonin and carvedilol on neural tube and skeletal system of mice fetuses in prenatal period.
    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2011, Oct-20, Volume: 193, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Bone Development; Carbazoles; Carvedilol; Cyclop

2011
Melatonin protects against clomiphene citrate-induced generation of hydrogen peroxide and morphological apoptotic changes in rat eggs.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Animals; Apoptosis; Catalase; Clomiphene; DNA Fragmentation; Female; Free Radical Scavengers; Humans

2011
Neuroprotection by melatonin after germinal matrix hemorrhage in neonatal rats.
    Acta neurochirurgica. Supplement, 2011, Volume: 111

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Atrophy; Cerebral Cortex; Cognition D

2011
Plasticity changes in adult metabolic homeostasis and tissue oxidative stress: neonatal programming by corticosterone and melatonin as deprogrammer.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:6

    Topics: Animals; Animals, Newborn; Body Weight; Corticosterone; Drinking; Eating; Female; Growth and Develop

2012
Melatonin concentration in umbilical cord blood depends on mode of delivery.
    Early human development, 2012, Volume: 88, Issue:6

    Topics: Adult; Cesarean Section; Circadian Rhythm; Delivery, Obstetric; Female; Fetal Blood; Humans; Infant,

2012
Prophylactic administration of melatonin to the mother throughout pregnancy can protect against oxidative cerebral damage in neonatal rats.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:8

    Topics: Animals; Animals, Newborn; Antioxidants; Cerebrum; Chemoprevention; Cytoprotection; Drug Administrat

2012
Melatonin supplementation alters uteroplacental hemodynamics and fetal development in an ovine model of intrauterine growth restriction.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2012, Feb-15, Volume: 302, Issue:4

    Topics: Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Dietary Supplements; Disease Mode

2012
Neonatal corticosterone programs for thrifty phenotype adult diabetic manifestations and oxidative stress: countering effect of melatonin as a deprogrammer.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:9

    Topics: Age of Onset; Animals; Animals, Newborn; Corticosterone; Diabetes Mellitus; Drug Antagonism; Female;

2012
Structural neuroplasticity induced by melatonin in entorhinal neurons of rats exposed to toluene inhalation.
    Acta neurobiologiae experimentalis, 2011, Volume: 71, Issue:4

    Topics: Administration, Inhalation; Animals; Dendrites; Entorhinal Cortex; Female; Melatonin; Neuronal Plast

2011
The relationship of nocturnal melatonin to estradiol and progesterone in depressed and healthy pregnant women.
    Journal of women's health (2002), 2012, Volume: 21, Issue:6

    Topics: Adult; Analysis of Variance; Body Mass Index; California; Circadian Rhythm; Depressive Disorder; Est

2012
The use of melatonin in hypoxic-ischemic brain damage: an experimental study.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25 Suppl 1

    Topics: Animals; Animals, Newborn; Antioxidants; Biomarkers; Drug Evaluation, Preclinical; Female; Hypoxia-I

2012
Impaired mouse mammary gland growth and development is mediated by melatonin and its MT1G protein-coupled receptor via repression of ERα, Akt1, and Stat5.
    Journal of pineal research, 2012, Volume: 53, Issue:3

    Topics: Animals; Estrogen Receptor alpha; Female; Lactation; Mammary Glands, Animal; Mammary Tumor Virus, Mo

2012
Placental melatonin production and melatonin receptor expression are altered in preeclampsia: new insights into the role of this hormone in pregnancy.
    Journal of pineal research, 2012, Volume: 53, Issue:4

    Topics: Acetylserotonin O-Methyltransferase; Adult; Arylalkylamine N-Acetyltransferase; Blotting, Western; C

2012
Maternal melatonin programs the daily pattern of energy metabolism in adult offspring.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Animals; Energy Metabolism; Female; Glucose Tolerance Test; Insulin; Insulin Resistance; Melatonin;

2012
Timed maternal melatonin treatment reverses circadian disruption of the fetal adrenal clock imposed by exposure to constant light.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; ARNTL Transcription Factors; Circadian Clocks;

2012
Melatonin treatment at dry-off improves reproductive performance postpartum in high-producing dairy cows under heat stress conditions.
    Reproduction in domestic animals = Zuchthygiene, 2013, Volume: 48, Issue:4

    Topics: Animals; Cattle; Drug Implants; Female; Gestational Age; Hot Temperature; Lactation; Melatonin; Preg

2013
Pulmonary innate immune response and melatonin receptors in the perinatal stress.
    Clinical & developmental immunology, 2013, Volume: 2013

    Topics: C-Reactive Protein; Cause of Death; Cytokines; Female; Fetal Hypoxia; Humans; Immunity, Innate; Immu

2013
Oxidative stress induced by phenylketonuria in the rat: Prevention by melatonin, vitamin E, and vitamin C.
    Journal of neuroscience research, 2002, Aug-15, Volume: 69, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Brain; Cerebellum; Disease Models, Animal; F

2002
Out-of-season breeding of milk goats--the effect of light treatment, melatonin and breed.
    Journal of the South African Veterinary Association, 2001, Volume: 72, Issue:4

    Topics: Animals; Breeding; Circadian Rhythm; Female; Goats; Light; Male; Melatonin; Photoperiod; Pregnancy;

2001
Variations of mt1 melatonin receptor density in the rat uterus during decidualization, the estrous cycle and in response to exogenous steroid treatment.
    Journal of pineal research, 2002, Volume: 33, Issue:3

    Topics: Animals; Decidua; Estradiol; Estrus; Female; Melatonin; Ovariectomy; Pregnancy; Progesterone; Rats;

2002
Effect of electric and magnetic fields (60 Hz) on production, and levels of growth hormone and insulin-like growth factor 1, in lactating, pregnant cows subjected to short days.
    Journal of dairy science, 2002, Volume: 85, Issue:11

    Topics: Animals; Cattle; Eating; Electromagnetic Fields; Environmental Exposure; Female; Growth Hormone; Ins

2002
Termination of neuroendocrine refractoriness to melatonin in Siberian hamsters (Phodopus sungorus).
    Journal of neuroendocrinology, 2003, Volume: 15, Issue:2

    Topics: Animals; Body Weight; Cricetinae; Female; Male; Melatonin; Neurosecretory Systems; Phodopus; Photope

2003
The human myometrium as a target for melatonin.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:2

    Topics: Adult; Cells, Cultured; Female; Gene Expression; Humans; Iodine Radioisotopes; Melatonin; Middle Age

2003
Melatonin is rhythmic in newborn seals exposed to continuous light.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2003, Volume: 173, Issue:1

    Topics: Animals; Animals, Newborn; Circadian Rhythm; Darkness; Female; Fetus; Lighting; Melatonin; Pineal Gl

2003
Maternal transfer of photoperiodic information in Siberian hamsters. vi. effects of time-dependent 1-hr melatonin infusions in the mother on photoperiod-induced testicular development of her offspring.
    Journal of pineal research, 2003, Volume: 34, Issue:3

    Topics: Animals; Circadian Rhythm; Cricetinae; Female; Male; Maternal-Fetal Exchange; Melatonin; Phodopus; P

2003
Circadian expression of Mel1a and PL-II genes in placenta: effects of melatonin on the PL-II gene expression in the rat placenta.
    Molecular and cellular endocrinology, 2003, Feb-28, Volume: 200, Issue:1-2

    Topics: Actins; Animals; Circadian Rhythm; Female; Gene Expression Regulation; Melatonin; Placenta; Placenta

2003
Pineal gland (melatonin) affects the parturition time, but not luteal function and fetal growth, in pregnant rats.
    Endocrine journal, 2003, Volume: 50, Issue:1

    Topics: Animals; Corpus Luteum; Embryonic and Fetal Development; Female; Melatonin; Parturition; Photoperiod

2003
Hormonal basis of mood and postpartum disorders.
    Current women's health reports, 2003, Volume: 3, Issue:3

    Topics: Adult; Case-Control Studies; Depression, Postpartum; Estrogens; Female; Hormones; Humans; Hydrocorti

2003
Melatonin receptor signaling in pregnant and nonpregnant rat uterine myocytes as probed by large conductance Ca2+-activated K+ channel activity.
    Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:10

    Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; GTP-Binding Protein alph

2003
Effect of stress on pregnancy outcome among women undergoing assisted reproduction procedures.
    Southern medical journal, 2003, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Female; Humans; Hydrocortisone; Infertility, Female; Me

2003
Physiological effects of shift work on hospital nurses.
    Journal of human ergology, 2001, Volume: 30, Issue:1-2

    Topics: Adult; Analysis of Variance; Arousal; Circadian Rhythm; Estriol; Female; Humans; Melatonin; Norepine

2001
[Effect of melatonin and/or diazepam on circadian rhythm of cultured myocardiocytes in rats].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2003, Volume: 34, Issue:4

    Topics: Animals; Animals, Newborn; Cells, Cultured; Circadian Rhythm; Female; Melatonin; Myocytes, Cardiac;

2003
Melatonin reduces noradrenaline-induced vasoconstriction in the uterine artery of pregnant hooded seals (Cystophora cristata).
    Pflugers Archiv : European journal of physiology, 2004, Volume: 447, Issue:4

    Topics: Animals; Arteries; Diving; Dose-Response Relationship, Drug; Female; Fetus; In Vitro Techniques; Mel

2004
Maternal melatonin selectively inhibits cortisol production in the primate fetal adrenal gland.
    The Journal of physiology, 2004, Feb-01, Volume: 554, Issue:Pt 3

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Animals, Newb

2004
Influence of oral melatonin on natural and gonadotropin-induced ovarian function in the domestic cat.
    Theriogenology, 2004, Apr-15, Volume: 61, Issue:6

    Topics: Animals; Cat Diseases; Cats; Chorionic Gonadotropin; Estrogens; Estrus; Feces; Female; Half-Life; In

2004
Local polynomial regression modeling of human plasma melatonin levels.
    Journal of biological rhythms, 2004, Volume: 19, Issue:2

    Topics: Area Under Curve; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Logistic Models; Melat

2004
Lack of effect of 10 kV/m 60 Hz electric field exposure on pregnant dairy heifer hormones.
    Bioelectromagnetics, 2004, Volume: 25, Issue:4

    Topics: Animals; Cattle; Electromagnetic Fields; Female; Insulin-Like Growth Factor I; Melatonin; Pregnancy;

2004
Effect of melatonin on neurobehavioral dysfunctions induced by intrauterine hypoxia in rats.
    Central European journal of public health, 2004, Volume: 12 Suppl

    Topics: Analysis of Variance; Animals; Behavior, Animal; Female; Hypoxia; Melatonin; Oxidative Stress; Pheny

2004
Effect of melatonin on biochemical variables induced by phenytoin in organs of mothers, foetuses and offsprings of rats.
    Central European journal of public health, 2004, Volume: 12 Suppl

    Topics: Acetylglucosaminidase; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Female; Glu

2004
Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration.
    Central European journal of public health, 2004, Volume: 12 Suppl

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Body

2004
Short day lengths delay reproductive aging.
    Biology of reproduction, 2004, Volume: 71, Issue:3

    Topics: Aging; Animals; Cricetinae; Female; Male; Melatonin; Phodopus; Photoperiod; Pineal Gland; Pregnancy;

2004
Seasonal changes of SP and NKA in frontal cortex, striatum and testes in the rat. Role of maternal pineal gland.
    Peptides, 2004, Volume: 25, Issue:6

    Topics: Animals; Brain; Female; Frontal Lobe; Male; Melatonin; Neostriatum; Neurokinin A; Pineal Gland; Preg

2004
Circadian melatonin concentration rhythm is lost in pregnant women with altered blood pressure rhythm.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 18, Issue:3

    Topics: Blood Pressure; Circadian Rhythm; Female; Gestational Age; Humans; Hypertension; Melatonin; Pre-Ecla

2004
Pharmacological effects of melatonin on reproductive activity: experimental bioimplants with sustained-release polymeric systems.
    Clinical and experimental obstetrics & gynecology, 2004, Volume: 31, Issue:2

    Topics: Absorbable Implants; Animals; Delayed-Action Preparations; Female; Fertility Agents, Female; Goats;

2004
Blood melatonin and prolactin concentrations in dairy cows exposed to 60 Hz electric and magnetic fields during 8 h photoperiods.
    Bioelectromagnetics, 2004, Volume: 25, Issue:7

    Topics: Animals; Cattle; Cross-Over Studies; Darkness; Electricity; Electromagnetic Fields; Environmental Ex

2004
Maternally administered melatonin protects against ischemia and reperfusion-induced oxidative mitochondrial damage in premature fetal rat brain.
    Journal of pineal research, 2004, Volume: 37, Issue:4

    Topics: Animals; Antioxidants; Brain; Cell Respiration; Female; Fetus; Melatonin; Mitochondria; Oxidative St

2004
Maternal fluoxetine infusion does not alter fetal endocrine and biophysical circadian rhythms in pregnant sheep.
    Journal of the Society for Gynecologic Investigation, 2005, Volume: 12, Issue:5

    Topics: Animals; Blood Pressure; Circadian Rhythm; Electrocardiography; Female; Fluoxetine; Heart Rate; Infu

2005
Perinatal influences of melatonin on testicular development and photoperiodic memory in Siberian hamsters.
    Journal of neuroendocrinology, 2005, Volume: 17, Issue:8

    Topics: Age Factors; Animals; Animals, Newborn; Biological Clocks; Cricetinae; Female; Male; Melatonin; Phod

2005
Antioxidant pretreatment does not ameliorate alcohol-induced Purkinje cell loss in the developing rat cerebellum.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:7

    Topics: Age Factors; Animals; Antioxidants; Cerebellum; Chromans; Ethanol; Female; Fetal Alcohol Spectrum Di

2005
Beneficial effects of melatonin on morphological changes in postnatal cerebellar tissue owing to epileptiform activity during pregnancy in rats: light and immunohistochemical study.
    Brain research. Developmental brain research, 2005, Oct-06, Volume: 159, Issue:2

    Topics: Animals; Cerebellum; Epilepsy; Female; Immunohistochemistry; Intermediate Filament Proteins; Melaton

2005
Alleviation of maternal hyperthermia-induced early embryonic death by administration of melatonin to mice.
    Journal of pineal research, 2005, Volume: 39, Issue:3

    Topics: Animals; Body Temperature; Embryo Loss; Female; Hypothermia; Male; Melatonin; Mice; Mice, Inbred ICR

2005
Melatonin as a local regulator of human placental function.
    Journal of pineal research, 2005, Volume: 39, Issue:3

    Topics: Acetylserotonin O-Methyltransferase; Arylalkylamine N-Acetyltransferase; Cells, Cultured; Chorionic

2005
Morphological and biochemical study of the pineal gland of pregnant and non-pregnant female vizcachas (Lagostomus maximus maximus).
    Neuro endocrinology letters, 2005, Volume: 26, Issue:5

    Topics: Acetylserotonin O-Methyltransferase; Animals; Arylalkylamine N-Acetyltransferase; Female; Melatonin;

2005
Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, Vitamin E, and Vitamin C.
    Neuroscience letters, 2006, Jan-09, Volume: 392, Issue:1-2

    Topics: Aldehydes; Animals; Animals, Newborn; Ascorbic Acid; Disease Models, Animal; Drug Interactions; Fema

2006
Melatonin protects against lipopolysaccharide-induced intra-uterine fetal death and growth retardation in mice.
    Journal of pineal research, 2006, Volume: 40, Issue:1

    Topics: Animals; Bone and Bones; Female; Fetal Death; Fetal Growth Retardation; Glutathione; Lipid Peroxidat

2006
Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2006, Volume: 22, Issue:5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Epilepsy; Female; Gene Expression

2006
Effects of supplementing pregnant heifers with methionine or melatonin on the anatomy and other characteristics of their lateral hind claws.
    The Veterinary record, 2006, Jan-07, Volume: 158, Issue:1

    Topics: Animal Feed; Animals; Cattle; Dietary Supplements; Female; Hardness; Hoof and Claw; Melatonin; Methi

2006
Highly synchronous and fertile reproductive activity induced by the male effect during deep anoestrus in lactating goats subjected to treatment with artificially long days followed by a natural photoperiod.
    Animal reproduction science, 2007, Volume: 98, Issue:3-4

    Topics: Anestrus; Animals; Delayed-Action Preparations; Female; Fertility; Flurogestone Acetate; Goats; Lact

2007
Physiological pineal effects on female reproductive function of laboratory rats: prenatal development of pups, litter size and estrous cycle in middle age.
    Chronobiology international, 2006, Volume: 23, Issue:1-2

    Topics: Aging; Animals; Congenital Abnormalities; Estrous Cycle; Female; Litter Size; Maternal Age; Melatoni

2006
Annual reproductive synchronization in ovary and pineal gland function of female short-nosed fruit bat, Cynopterus sphinx.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2006, Volume: 144, Issue:4

    Topics: Acclimatization; Animals; Chiroptera; Embryonic Development; Estradiol; Female; Melatonin; Organ Siz

2006
Maternal melatonin effects on clock gene expression in a nonhuman primate fetus.
    Endocrinology, 2006, Volume: 147, Issue:10

    Topics: Adrenal Glands; Animals; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors;

2006
Injury switches melatonin production source from endocrine (pineal) to paracrine (phagocytes) - melatonin in human colostrum and colostrum phagocytes.
    Journal of pineal research, 2006, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Colostrum; Escherichia coli; Female; Humans; Infant; Mastitis; Melatonin; Paracri

2006
Pup circadian rhythm entrainment--effect of maternal ganglionectomy or pinealectomy.
    Physiology & behavior, 2006, Oct-30, Volume: 89, Issue:3

    Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Circadian Rhythm; Drinking Behavi

2006
Melatonin has dose-dependent effects on folliculogenesis, oocyte maturation capacity and steroidogenesis.
    Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3

    Topics: Androstenedione; Animals; Dose-Response Relationship, Drug; Estrogens; Female; Melatonin; Mice; Mice

2006
Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion.
    Pediatric research, 2007, Volume: 61, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Asphyxia; Blood Gas Analysis; Blood Pressure; Brain; Cell Death;

2007
Efficacy of melatonin on offspring liver maturation in pinealectomized pregnant rats subjected to experimental epilepsy.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:4

    Topics: Animals; Epilepsy; Female; In Situ Nick-End Labeling; Liver; Melatonin; Pineal Gland; Pregnancy; Pre

2007
Effects of melatonin on the endometrial morphology and embryo implantation in rats.
    Fertility and sterility, 2008, Volume: 89, Issue:5 Suppl

    Topics: Animals; Body Weight; Embryo Implantation; Endometrium; Estradiol; Female; Male; Melatonin; Organ Si

2008
Neuroprotective effects of melatonin upon the offspring cerebellar cortex in the rat model of BCNU-induced cortical dysplasia.
    Brain research, 2007, Jul-30, Volume: 1160

    Topics: Animals; Animals, Newborn; Brain Diseases; Bromodeoxyuridine; Carmustine; Cerebellar Cortex; Disease

2007
Maternally administered melatonin differentially regulates lipopolysaccharide-induced proinflammatory and anti-inflammatory cytokines in maternal serum, amniotic fluid, fetal liver, and fetal brain.
    Journal of pineal research, 2007, Volume: 43, Issue:1

    Topics: Amniotic Fluid; Animals; Brain; Cytokines; Female; Fetal Proteins; Fetus; Inflammation Mediators; Li

2007
The circadian system is a target and modulator of prenatal cocaine effects.
    PloS one, 2007, Jul-11, Volume: 2, Issue:7

    Topics: Animals; Animals, Genetically Modified; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Embryo

2007
Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio.
    Journal of pineal research, 2007, Volume: 43, Issue:2

    Topics: Animals; Apoptosis; Body Weight; Cholestasis; Female; Glutathione; Lipid Peroxidation; Liver; Melato

2007
Pineal melatonin and the innate immune response: the TNF-alpha increase after cesarean section suppresses nocturnal melatonin production.
    Journal of pineal research, 2007, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Cesarean Section; Circadian Rhythm; Colostrum; Cytokines; Female; Humans; Interfe

2007
Melatonin regulates the viability and differentiation of rat midbrain neural stem cells.
    Cellular and molecular neurobiology, 2008, Volume: 28, Issue:4

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Survival; Cells, Cultured; Do

2008
[Effect of melatonin on the activation and proliferation of neonatal cord blood mononuclear cell].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2007, Volume: 45, Issue:7

    Topics: Adult; Blood Cells; Cell Culture Techniques; Cell Proliferation; Cells; Cells, Cultured; Female; Fet

2007
Melatonin-improved reproductive performance in sheep bred out of season.
    Animal reproduction science, 2008, Volume: 109, Issue:1-4

    Topics: Animals; Chorionic Gonadotropin; Estrus; Female; Fertility; Horses; Litter Size; Melatonin; New Zeal

2008
Melatonin prevents gestational hyperhomocysteinemia-associated alterations in neurobehavioral developments in rats.
    Journal of pineal research, 2008, Volume: 44, Issue:2

    Topics: Animals; Animals, Newborn; Behavior, Animal; Cognition Disorders; Female; Hyperhomocysteinemia; Male

2008
Human placental trophoblasts synthesize melatonin and express its receptors.
    Journal of pineal research, 2008, Volume: 45, Issue:1

    Topics: Acetylserotonin O-Methyltransferase; Arylalkylamine N-Acetyltransferase; Cell Differentiation; Cell

2008
Anti-apoptotic effect of melatonin on preimplantation development of porcine parthenogenetic embryos.
    Molecular reproduction and development, 2008, Volume: 75, Issue:7

    Topics: Animals; Apoptosis; Blastocyst; Embryonic Development; Female; In Situ Nick-End Labeling; Melatonin;

2008
Fetal/placental regulation of maternal melatonin in rats.
    Journal of pineal research, 2008, Volume: 44, Issue:3

    Topics: Animals; Arylalkylamine N-Acetyltransferase; Circadian Rhythm; Female; Fetus; Melatonin; Placenta; P

2008
Melatonin preserves fetal growth in rats by protecting against ischemia/reperfusion-induced oxidative/nitrosative mitochondrial damage in the placenta.
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; DNA Damage; DNA-(Apurinic or Apyrimidinic Site

2008
Effects of melatonin and undernutrition on the viability of ovine embryos during anestrus and the breeding season.
    Animal reproduction science, 2009, Volume: 112, Issue:1-2

    Topics: Anestrus; Animals; Breeding; Diet; Drug Implants; Embryo Loss; Embryonic Development; Female; Insemi

2009
Response of pineal beta-adrenoceptors in different breeds of sheep to immunization against selected steroids.
    Biochemical pharmacology, 1984, Aug-15, Volume: 33, Issue:16

    Topics: Androgens; Animals; Estrogens; Estrus; Female; Gonadal Steroid Hormones; Humans; Immunization; Melat

1984
Melatonin-induced changes in blood and pituitary luteinizing hormone and prolactin levels during the perinatal period in rat dams.
    Journal of neural transmission, 1980, Volume: 49, Issue:4

    Topics: Animals; Estradiol; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Melatonin; Pineal G

1980
Is the role of melatonin in induction of ovulation in the light-induced constant estrous anovulatory state mediated through the brain serotonergic system?
    Reproduction, nutrition, developpement, 1980, Volume: 20, Issue:6

    Topics: Animals; Anovulation; Brain; Estrus; Female; Hydroxyindoleacetic Acid; Light; Melatonin; Mesencephal

1980
Melatonin inhibits beta-adrenoceptor-stimulated cyclic AMP accumulation in rat astroglial cell cultures.
    Neuroendocrinology, 1984, Volume: 38, Issue:3

    Topics: Animals; Astrocytes; Brain; Cells, Cultured; Cyclic AMP; Female; Melatonin; Pregnancy; Rats; Rats, I

1984
Depressive effect of LHRH on the numbers of "synaptic" ribbons and spherules in the pineal gland of diestrous rats.
    Cell and tissue research, 1983, Volume: 229, Issue:2

    Topics: Animals; Diestrus; Female; Gonadotropin-Releasing Hormone; Melatonin; Pineal Gland; Pregnancy; Rats;

1983
Photoperiod and melatonin influence seasonal gonadal cycles in the grasshopper mouse (Onychomys leucogaster).
    Journal of reproduction and fertility, 1983, Volume: 69, Issue:1

    Topics: Animals; Arvicolinae; Estrus; Female; Light; Male; Melatonin; Periodicity; Pregnancy; Seasons; Sexua

1983
Effect of varying photoperiods on mammary morphology, DNA synthesis, and hormone profile in female rats.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Cell Transformation, Neoplastic; Darkness;

1984
Response to melatonin in brain areas implicated in the sexual cycle of the rat.
    Brain research, 1984, Apr-02, Volume: 296, Issue:2

    Topics: Amygdala; Animals; Brain; Castration; Cerebral Cortex; Energy Metabolism; Estrus; Female; Hypothalam

1984
Sex and strain related effects of melatonin and 5-methoxytryptophol on open field behaviour in paired mice.
    Behavioural brain research, 1984, Volume: 13, Issue:2

    Topics: Animals; Behavior, Animal; Eliminative Behavior, Animal; Estrus; Female; Indoles; Male; Melatonin; M

1984
Effect of feeding melatonin to red deer (Cervus elaphus) on the onset of the breeding season.
    Journal of reproduction and fertility, 1984, Volume: 72, Issue:2

    Topics: Animals; Antlers; Deer; Estrus; Female; Male; Melatonin; Pregnancy; Progesterone; Seasons; Sexual Be

1984
[Role of the somatotropic activity of the adenohypophysis and the epiphysis in the development of large fetuses].
    Akusherstvo i ginekologiia, 1983, Issue:5

    Topics: Birth Weight; Female; Fetus; Growth Hormone; Humans; Melatonin; Pineal Gland; Pituitary Gland, Anter

1983
Evidence for prolactin-releasing and release-inhibiting effects of melatonin, serotonin and arginine vasotocin.
    The Tohoku journal of experimental medicine, 1983, Volume: 141, Issue:1

    Topics: Animals; Estradiol Congeners; Female; Melatonin; Ovary; Pineal Gland; Postpartum Period; Pregnancy;

1983
Melatonin can induce early onset of the breeding season in ewes.
    The Journal of endocrinology, 1983, Volume: 97, Issue:3

    Topics: Animals; Estrus; Female; Light; Melatonin; Periodicity; Pregnancy; Sheep

1983
Follicular growth and intraovarian and extraovarian oocyte release after daily injections of melatonin and 6-chloro-melatonin in the Syrian hamster.
    The American journal of anatomy, 1983, Volume: 167, Issue:3

    Topics: Animals; Cricetinae; Estrus; Female; Melatonin; Mesocricetus; Oocytes; Organ Size; Ovarian Follicle;

1983
Inhibition by melatonin of dopamine release from rat hypothalamus in vitro: variations with sex and the estrous cycle.
    Neuroendocrinology, 1983, Volume: 37, Issue:1

    Topics: Animals; Diestrus; Dopamine; Electric Stimulation; Estrus; Female; Hypothalamus; Kinetics; Male; Mel

1983
Influence of morning melatonin injections on the antigonadotrophic effects of afternoon melatonin administration in male and female hamsters.
    Neuroendocrinology, 1981, Volume: 33, Issue:2

    Topics: Animals; Circadian Rhythm; Cricetinae; Estrus; Female; Follicle Stimulating Hormone; Genitalia, Male

1981
The anovulatory hamster: a comparison of the effects of short photoperiod and daily melatonin injections on the induction and termination of ovarian acyclicity.
    The Journal of experimental zoology, 1981, Volume: 215, Issue:2

    Topics: Animals; Cricetinae; Estrus; Female; Follicle Stimulating Hormone; Light; Luteinizing Hormone; Melat

1981
Effect of melatonin feeding on serum prolactin and gonadotropin levels and the onset of seasonal estrous cyclicity in sheep.
    Endocrinology, 1982, Volume: 110, Issue:5

    Topics: Animals; Circadian Rhythm; Estrus; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Melato

1982
Photoperiodic stimulation of the mare during winter anoestrus.
    Journal of reproduction and fertility. Supplement, 1982, Volume: 32

    Topics: Anestrus; Animals; Circadian Rhythm; Darkness; Estrus; Female; Follicle Stimulating Hormone; Horses;

1982
Ontogeny of the gonadal response of golden hamsters to short photoperiod, blinding, and melatonin.
    Biology of reproduction, 1982, Volume: 27, Issue:4

    Topics: Aging; Animals; Blindness; Cricetinae; Estrus; Female; Gonads; Light; Male; Melatonin; Mesocricetus;

1982
Pineal melatonin synthesis in Syrian hamsters: a summary.
    International journal of biometeorology, 1982, Volume: 26, Issue:4

    Topics: Animals; Circadian Rhythm; Cricetinae; Estrus; Female; Light; Male; Melatonin; Mesocricetus; Periodi

1982
Inhibition of luteinizing hormone release and ovulation by 6-chloro- and 6-fluoromelatonin.
    Neuroendocrinology, 1980, Volume: 30, Issue:2

    Topics: Animals; Diestrus; Female; Half-Life; Kinetics; Luteinizing Hormone; Melatonin; Ovulation; Pregnancy

1980
Melatonin given in the morning prevents the suppressive action on the reproductive system of melatonin given in late afternoon.
    Neuroendocrinology, 1980, Volume: 31, Issue:2

    Topics: Animals; Circadian Rhythm; Cricetinae; Estrus; Female; Luteinizing Hormone; Melatonin; Pregnancy; Pr

1980
Pineal function in the sheep: evidence for a possible mechanism mediating seasonal reproductive activity.
    Experientia, 1981, Volume: 37, Issue:6

    Topics: Animals; Circadian Rhythm; Estrus; Female; Melatonin; Pineal Gland; Pregnancy; Reproduction; Seasons

1981
Variation in pineal melatonin content during the estrous cycle of the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 169, Issue:3

    Topics: Animals; Circadian Rhythm; Estrus; Female; Kinetics; Melatonin; Pineal Gland; Pregnancy; Rats; Rats,

1982
Modulation of gonadal activity by timed injections of melatonin in pinealectomized or intact ferrets kept under two photoperiods.
    The Journal of endocrinology, 1982, Volume: 93, Issue:2

    Topics: Anestrus; Animals; Carnivora; Estrus; Female; Ferrets; Light; Melatonin; Periodicity; Pineal Gland;

1982
The effect of melatonin and other indole derivatives in maintaining ovulation in rats kept in continuous light and the influence of these indoles on HIOMT activity in the pineal gland.
    Journal of neural transmission, 1982, Volume: 53, Issue:4

    Topics: Acetylserotonin O-Methyltransferase; Animals; Estrus; Female; Indoles; Light; Melatonin; Methyltrans

1982
Melatonin and the influence of the pineal gland on timing of the LH surge in rats.
    Neuroendocrinology, 1982, Volume: 35, Issue:1

    Topics: Animals; Female; Light; Luteinizing Hormone; Melatonin; Pineal Gland; Pregnancy; Proestrus; Quipazin

1982
Melatonin:serotonin interaction during termination of the LH surge in rats.
    Progress in clinical and biological research, 1982, Volume: 92

    Topics: Animals; Darkness; Environment, Controlled; Female; Luteinizing Hormone; Melatonin; Pineal Gland; Pr

1982
Melatonin injection into Syrian hamsters.
    Progress in clinical and biological research, 1982, Volume: 92

    Topics: Animals; Circadian Rhythm; Cricetinae; Environment, Controlled; Estrus; Female; Light; Male; Melaton

1982
[Functional state of the epiphysis according to melatonin excretion data and the lactation function in puerperae].
    Akusherstvo i ginekologiia, 1980, Issue:2

    Topics: Female; Humans; Lactation; Lactation Disorders; Melatonin; Pineal Gland; Postpartum Period; Pregnanc

1980
Development of pre-implantation mouse embryos under the influence of pineal indoles.
    Journal of neural transmission. General section, 1994, Volume: 96, Issue:1

    Topics: 5-Methoxytryptamine; Abnormalities, Drug-Induced; Animals; Blastocyst; Embryonic and Fetal Developme

1994
Changes induced by pineal indoles in post-implantation mouse embryos.
    General pharmacology, 1995, Volume: 26, Issue:5

    Topics: 5-Methoxytryptamine; Animals; Embryo Implantation; Embryonic and Fetal Development; Female; Hydroxyi

1995
6-sulfatoxymelatonin levels in pregnant women during workplace and nonworkplace stresses: a potential biologic marker of sympathetic activity.
    American journal of perinatology, 1995, Volume: 12, Issue:4

    Topics: Biomarkers; Catecholamines; Female; Humans; Melatonin; Pregnancy; Stress, Physiological; Sympathetic

1995
Melatonin and the development of circadian and seasonal rhythmicity.
    Journal of reproduction and fertility. Supplement, 1995, Volume: 49

    Topics: Animals; Circadian Rhythm; Embryonic and Fetal Development; Female; Fetal Blood; Melatonin; Periodic

1995
Influence of prenatal photoperiods on postnatal reproductive responses to daily infusions of melatonin in the Siberian hamster (Phodopus sungorus).
    Endocrinology, 1995, Volume: 136, Issue:10

    Topics: Animals; Cricetinae; Female; Follicle Stimulating Hormone; Light; Male; Melatonin; Organ Size; Phodo

1995
Gender differences in influence of prenatal photoperiods on postnatal pineal melatonin rhythms and serum prolactin and follicle-stimulating hormone in the Siberian hamster (Phodopus sungorus).
    Endocrinology, 1995, Volume: 136, Issue:10

    Topics: Animals; Cricetinae; Female; Follicle Stimulating Hormone; Light; Male; Melatonin; Phodopus; Pineal

1995
Effect of photoperiod on the pineal melatonin rhythm in neonatal rats.
    Neuroscience letters, 1994, Oct-24, Volume: 180, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Animals, Suckling; Eye; Female; Luteinizing Hormone; Melaton

1994
Effect of pinealectomy and melatonin treatment during pregnancy on the sexual development of the female and male rat offspring.
    European journal of endocrinology, 1995, Volume: 132, Issue:6

    Topics: Animals; Animals, Newborn; Female; Fetal Blood; Follicle Stimulating Hormone; Hypothalamo-Hypophysea

1995
Evidence for hypothalamic control of the diurnal rhythms in prolactin and melatonin in the fetal sheep during late gestation.
    Endocrinology, 1995, Volume: 136, Issue:1

    Topics: Animals; Circadian Rhythm; Female; Fetal Blood; Fetus; Gestational Age; Hypothalamus; Melatonin; Osm

1995
Melatonin influences sex-specific prenatal mortality in meadow voles.
    Biology of reproduction, 1994, Volume: 51, Issue:5

    Topics: Animals; Arvicolinae; Blastocyst; Embryo Implantation; Female; Fetal Death; Litter Size; Male; Melat

1994
Seasonal variation of twin births in Washington State.
    Acta geneticae medicae et gemellologiae, 1993, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Birth Certificates; Birth Rate; Case-Control Studies; Female; Gestational Age; Go

1993
Melatonin and hormonal changes in disturbed sleep during late pregnancy.
    Journal of pineal research, 1993, Volume: 15, Issue:4

    Topics: Adult; Circadian Rhythm; Female; Humans; Hydrocortisone; Melatonin; Pregnancy; Pregnancy Complicatio

1993
Influence of simulated photoperiod alteration and induced estrus on reproductive performance of spring-born Columbia and Targhee ewe lambs.
    Journal of animal science, 1994, Volume: 72, Issue:1

    Topics: Animals; Breeding; Estrus Synchronization; Female; Gonadotropins, Equine; Medroxyprogesterone Acetat

1994
Effect of sympathetic denervation of the pineal gland on maternal co-ordination of the circadian rhythm of alpha-amylase in parotid gland from young rats.
    Archives of oral biology, 1993, Volume: 38, Issue:12

    Topics: alpha-Amylases; Animals; Circadian Rhythm; Female; Male; Maternal-Fetal Exchange; Melatonin; Mothers

1993
Effects of exogenous melatonin on prolactin secretion, lactogenesis and reproductive seasonality of adult female red deer (Cervus elaphus).
    Journal of reproduction and fertility, 1994, Volume: 100, Issue:1

    Topics: Animals; Birth Weight; Deer; Female; Lactation; Mammary Glands, Animal; Melatonin; Pregnancy; Pregna

1994
Sex steroids do not alter melatonin secretion in the human.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:1

    Topics: Adult; Contraceptives, Oral; Female; Gonadal Steroid Hormones; Humans; Melatonin; Menstrual Cycle; O

1994
HPLC assay of melatonin in plasma with fluorescence detection.
    Clinical chemistry, 1993, Volume: 39, Issue:11 Pt 1

    Topics: Adolescent; Adult; Aged; Child; Chromatography, High Pressure Liquid; Circadian Rhythm; Female; Fluo

1993
Effect of melatonin on pituitary secretion of prolactin in vitro during delayed implantation and the periimplantation period in the spotted skunk.
    The Journal of experimental zoology, 1993, Dec-01, Volume: 267, Issue:5

    Topics: Animals; Dopamine; Embryonic Development; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Mela

1993
Melatonin and the light-dark cycle separately influence daily behavioral and hormonal rhythms in the pregnant ewe and sheep fetus.
    Endocrinology, 1993, Volume: 133, Issue:1

    Topics: Animals; Behavior, Animal; Blood Glucose; Cerebral Cortex; Electrophysiology; Female; Fetal Blood; F

1993
Developmental appearance and age related changes in specific 2-[125I]iodomelatonin binding sites in the suprachiasmatic nuclei of female Syrian hamsters.
    Brain research. Developmental brain research, 1993, Jun-08, Volume: 73, Issue:2

    Topics: Aging; Animals; Autoradiography; Circadian Rhythm; Cricetinae; Female; Iodine Radioisotopes; Melaton

1993
The fetal circadian pacemaker is not involved in the timing of birth in hamsters.
    Biology of reproduction, 1993, Volume: 48, Issue:3

    Topics: Animals; Circadian Rhythm; Cricetinae; Female; Fetus; Labor, Obstetric; Melatonin; Mesocricetus; Mut

1993
Somnolence associated with melatonin deficiency after pinealectomy.
    Lancet (London, England), 1996, Feb-03, Volume: 347, Issue:8997

    Topics: Adult; Disorders of Excessive Somnolence; Female; Humans; Melatonin; Pineal Gland; Pregnancy; Puerpe

1996
Maternal pineal gland participates in prepubertal rats' ovarian oocyte development.
    The Anatomical record, 1995, Volume: 243, Issue:4

    Topics: Animals; Female; Melatonin; Oocytes; Pineal Gland; Pregnancy; Prenatal Exposure Delayed Effects; Rat

1995
Factors influencing the development of melatonin rhythmicity in humans.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:4

    Topics: Birth Weight; Cesarean Section; Female; Fetal Growth Retardation; Fetal Membranes, Premature Rupture

1996
The effect of melatonin treatment on reproductive efficiency in an accelerated lambing system.
    Journal of the South African Veterinary Association, 1995, Volume: 66, Issue:4

    Topics: Animals; Cattle; Drug Implants; Female; Fertility; Litter Size; Melatonin; Periodicity; Pregnancy; S

1995
Entrainment of Syrian hamster circadian activity rhythms by neonatal melatonin injections.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 2

    Topics: Animals; Animals, Newborn; Circadian Rhythm; Cricetinae; Female; Male; Melatonin; Mesocricetus; Preg

1996
Melatonin-induced downregulation of uterine prolactin receptors in mink (Mustela vison).
    General and comparative endocrinology, 1996, Volume: 103, Issue:1

    Topics: Animals; Down-Regulation; Estradiol; Female; Iodine Radioisotopes; Melatonin; Mink; Pregnancy; Proge

1996
The effect of melatonin on cleavage rate of C57BL/6 and CBA/Ca preimplantation embryos cultured in vitro.
    Journal of pineal research, 1996, Volume: 21, Issue:1

    Topics: Animals; Blastocyst; Cell Division; Cleavage Stage, Ovum; Embryo, Mammalian; Embryonic and Fetal Dev

1996
Prenatal development of the sheep pineal gland: an ultrastructural study.
    Journal of pineal research, 1996, Volume: 21, Issue:3

    Topics: Animals; Embryo, Mammalian; Female; Male; Melatonin; Pineal Gland; Pregnancy; Sheep

1996
Ontogeny of pineal melatonin rhythm in rats under 12:12-hr and 14:14-hr light:dark conditions.
    Journal of pineal research, 1996, Volume: 21, Issue:3

    Topics: Animals; Animals, Newborn; Circadian Rhythm; Dark Adaptation; Female; Male; Melatonin; Photoperiod;

1996
Photoperiodic history and hypothalamic control of prolactin secretion before birth.
    Endocrinology, 1997, Volume: 138, Issue:4

    Topics: Animals; Animals, Newborn; Body Weight; Female; Fetus; Gestational Age; Hypothalamo-Hypophyseal Syst

1997
Single prenatal injections of melatonin or the D1-dopamine receptor agonist SKF 38393 to pregnant hamsters sets the offsprings' circadian rhythms to phases 180 degrees apart.
    Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1997, Volume: 180, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Circadian Rhythm; Cricetinae; F

1997
The characteristics of the melatonin secretory rhythm are not modified by the stage of pregnancy in ewes.
    Reproduction, nutrition, development, 1997, Volume: 37, Issue:1

    Topics: Animals; Circadian Rhythm; Estrus; Female; Melatonin; Photoperiod; Pregnancy; Pregnancy, Animal; Pro

1997
Clarifying plasma melatonin profiles in domestic pigs: a critical and comparative evaluation of two radioimmunoassay systems.
    Journal of pineal research, 1997, Volume: 22, Issue:2

    Topics: Animals; Evaluation Studies as Topic; Fatty Acids, Nonesterified; Female; Melatonin; Pregnancy; Radi

1997
Melatonin inhibits vasospastic action of hydrogen peroxide in human umbilical artery.
    Journal of pineal research, 1997, Volume: 22, Issue:3

    Topics: Antioxidants; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; In Vitro Techniques; Infan

1997
Melatonin suppresses vasospastic effect of hydrogen peroxide in human umbilical artery: relation to calcium influx.
    Journal of pineal research, 1997, Volume: 22, Issue:4

    Topics: Adult; Calcium; Dose-Response Relationship, Drug; Female; Humans; Hydrogen Peroxide; Mannitol; Melat

1997
Metabolic costs of mounting an antigen-stimulated immune response in adult and aged C57BL/6J mice.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Aging; Animals; Antibody Formation; Antigens; Body Temperature; Body Temperature Regulation; Calorim

1997
[Melatonin: use and abuse].
    Medicina clinica, 1997, Sep-13, Volume: 109, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Antioxidants; Child; Circadian Rhythm; Contraceptives,

1997
Commentary on the articles by Arendt, Weaver, Mahle et al., and Guardiola-Lemaître.
    Journal of biological rhythms, 1997, Volume: 12, Issue:6

    Topics: Circadian Rhythm; Female; Humans; Melatonin; Pregnancy

1997
Melatonin entrainment of the circadian N-acetyltransferase rhythm in the newborn rat pineal gland.
    Journal of pineal research, 1997, Volume: 23, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Arylamine N-Acetyltransferase; Circadian Rhythm; Female; In

1997
Fetal and maternal diurnal rhythms during the third trimester of normal pregnancy: outcomes of computerized analysis of continuous twenty-four-hour fetal heart rate recordings.
    American journal of obstetrics and gynecology, 1998, Volume: 178, Issue:2

    Topics: Circadian Rhythm; Computers; Estriol; Female; Fetal Monitoring; Gestational Age; Heart Rate, Fetal;

1998
Effects of electric and magnetic fields on nocturnal melatonin concentrations in dairy cows.
    Journal of dairy science, 1998, Volume: 81, Issue:3

    Topics: Animals; Cattle; Circadian Rhythm; Electromagnetic Fields; Female; Lactation; Melatonin; Pregnancy

1998
Short note: The fetal origins hypothesis: linking pineal gland hypoplasia with coronary heart disease and stroke.
    Medical hypotheses, 1998, Volume: 50, Issue:4

    Topics: Cerebrovascular Disorders; Coronary Disease; Female; Humans; Infant, Newborn; Melatonin; Pineal Glan

1998
Maternal-fetal transfer of melatonin in pregnant women near term.
    Journal of pineal research, 1998, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Biological Transport; Chromatography, High Pressure Liquid; Female; Fetal Blood;

1998
Melatonin directly suppresses steroid production by preovulatory follicles in the cyclic hamster.
    Journal of pineal research, 1998, Volume: 25, Issue:3

    Topics: Animals; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Estradiol; Estrus; Female; Melato

1998
Diurnal rhythm of melatonin in bovine milk: pharmacokinetics of exogenous melatonin in lactating cows and goats.
    Acta veterinaria Scandinavica, 1998, Volume: 39, Issue:3

    Topics: Animal Husbandry; Animals; Area Under Curve; Cattle; Circadian Rhythm; Female; Goats; Half-Life; Lac

1998
Low ACTH and high melatonin concentrations in amniotic fluid as hormonal markers of high risk of fetal abnormalities. Preliminary studies.
    Prenatal diagnosis, 1998, Volume: 18, Issue:9

    Topics: Adrenocorticotropic Hormone; Amniotic Fluid; Congenital Abnormalities; Female; Fetal Diseases; Human

1998
Can high maternal melatonin concentrations be responsible for inducing fetal pathologies, and can melatonin participate in immunohormonal homeostasis by determining prohormone convertase activity?--Hypothesis and facts.
    Medical hypotheses, 1998, Volume: 51, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Congenital Abnormalities; Female; Fetal Diseases; Furin; Homeo

1998
Alteration by maternal pinealectomy of fetal and neonatal melatonin and dopamine D1 receptor binding in the suprachiasmatic nuclei.
    Biochemical and biophysical research communications, 1998, Dec-30, Volume: 253, Issue:3

    Topics: Animals; Animals, Newborn; Autoradiography; Benzazepines; Biological Transport; Blood Circulation; C

1998
Effects of melatonin, progestagens, and the ram on out-of-season reproduction in Swedish Landrace finewool sheep.
    Acta veterinaria Scandinavica, 1998, Volume: 39, Issue:4

    Topics: Animals; Breeding; Estrus; Female; Immunoassay; Litter Size; Male; Melatonin; Ovulation; Pregnancy;

1998
[Melatonin: myth or reality?].
    Investigacion clinica, 1998, Volume: 39, Issue:4

    Topics: Adjuvants, Immunologic; Adult; Animals; Antioxidants; Cattle; Child; Contraindications; Controlled C

1998
Prenatal melatonin influences developmental changes of tachykinins in response to estradiol benzoate.
    Peptides, 1999, Volume: 20, Issue:1

    Topics: Animals; Antioxidants; Corpus Striatum; Estradiol; Female; Hypothalamus; Melatonin; Pineal Gland; Pi

1999
Antioxidant transport by the human placenta.
    Clinical nutrition (Edinburgh, Scotland), 1998, Volume: 17, Issue:4

    Topics: Antioxidants; Biological Transport, Active; Female; Fetal Alcohol Spectrum Disorders; Humans; Matern

1998
Transient entrainment of a circadian pacemaker during development by dopaminergic activation in Syrian hamsters.
    Brain research bulletin, 1999, Jan-15, Volume: 48, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Circadian Rhythm; Cricet

1999
Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain.
    Journal of pineal research, 1999, Volume: 26, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Brain; Brain Ischemia; Deoxyguanosine; DNA; DNA Damage; Female

1999
Developmental changes of hypothalamic, pituitary and striatal tachykinins in response to testosterone: influence of prenatal melatonin.
    Peptides, 1999, Volume: 20, Issue:4

    Topics: Animals; Corpus Striatum; Female; Hypothalamus; Male; Melatonin; Neurokinin A; Pituitary Gland, Ante

1999
The effects on reproductive performance in the short and medium term of the combined use of exogenous melatonin and progestagen pessaries in ewes with a short seasonal anoestrous period.
    Veterinary research communications, 1999, Volume: 23, Issue:4

    Topics: Administration, Intravaginal; Anestrus; Animals; Drug Implants; Female; Gonadotropins, Equine; Male;

1999
Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 50, Issue:2

    Topics: Animals; Antioxidants; Aversive Therapy; Body Weight; Drinking; Eating; Female; Fetus; Male; Materna

1999
Melatonin inhibits the vasorelaxant action of peroxynitrite in human umbilical artery.
    Journal of pineal research, 1999, Volume: 27, Issue:2

    Topics: Antioxidants; Female; Free Radical Scavengers; Humans; In Vitro Techniques; Melatonin; Molsidomine;

1999
Psychobiological markers of stress in pregnancy: 6-sulfatoxymelatonin--a longitudinal study.
    American journal of perinatology, 1999, Volume: 16, Issue:5

    Topics: Adult; Anxiety; Biomarkers; Female; Gestational Age; Humans; Hydrocortisone; Melatonin; Pregnancy; P

1999
Maternal photoperiodic exposures alter the neonatal growth, pineal functions and sexual development of the Indian palm squirrel F. pennanti. Short communication.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:9-10

    Topics: Animals; Body Weight; Estradiol; Female; Gonads; Light; Male; Melatonin; Organ Size; Periodicity; Ph

1999
The effect of melatonin on in vitro fertilization and embryo development in mice.
    Journal of pineal research, 2000, Volume: 28, Issue:1

    Topics: Animals; Blastocyst; Embryonic and Fetal Development; Embryonic Development; Female; Fertilization i

2000
Colloid in the pituitary pars distalis of viscacha (Lagostomus maximus maximus): ultrastructure and occurrence in relation to season, sex, and growth.
    The Anatomical record, 2000, 03-01, Volume: 258, Issue:3

    Topics: Age Factors; Animals; Body Weight; Colloids; Female; Male; Melatonin; Microscopy, Electron; Neurons;

2000
Melatonin increases activities of glutathione peroxidase and superoxide dismutase in fetal rat brain.
    Journal of pineal research, 2000, Volume: 28, Issue:2

    Topics: Animals; Antioxidants; Brain; Female; Fetal Blood; Fetus; Free Radical Scavengers; Glutathione Perox

2000
Physical mapping of porcine seasonality genes.
    Animal biotechnology, 1999, Volume: 10, Issue:3

    Topics: Abortion, Veterinary; Animals; Chromosome Mapping; Female; Genome; Infertility; Melatonin; Photoperi

1999
Melatonin treatment of embryo donor and recipient ewes during anestrus affects their endocrine status, but not ovulation rate, embryo survival or pregnancy.
    Theriogenology, 1998, Apr-01, Volume: 49, Issue:5

    Topics: Anestrus; Animals; Embryo Transfer; Embryonic and Fetal Development; Estrus; Female; Follicle Stimul

1998
Melatonin protects against the free radical-induced impairment of nitric oxide production in the human umbilical artery.
    Journal of pineal research, 2000, Volume: 28, Issue:3

    Topics: Adult; Antioxidants; Arginine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Dru

2000
Melatonin inhibits NADPH-dependent lipid peroxidation in human placental mitochondria.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2000, Volume: 32, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Female; Humans; Lipid Peroxidation; Melatonin; Mitochondria; NADP; Plac

2000
Male reproductive condition is the limiting factor of efficiency in the male effect during seasonal anestrus in female goats.
    Biology of reproduction, 2000, Volume: 62, Issue:5

    Topics: Animals; Estrus; Female; Goats; Male; Melatonin; Pregnancy; Pregnancy Rate; Reproduction; Seasons; S

2000
Long-term supplementation with melatonin delays reproductive senescence in rats, without an effect on number of primordial follicles.
    Experimental gerontology, 2000, Volume: 35, Issue:3

    Topics: Aging; Animals; Drug Administration Schedule; Female; Male; Melatonin; Ovarian Follicle; Ovarian Neo

2000
Impact of photoperiodic exposures during late gestation and lactation periods on the pineal and reproductive physiology of the Indian palm squirrel, Funambulus pennanti.
    Journal of reproduction and fertility, 2000, Volume: 118, Issue:2

    Topics: Analysis of Variance; Animals; Biological Clocks; Estradiol; Female; In Vitro Techniques; Lactation;

2000
Effects of neonatal melatonin administration on the extra-hypothalamic regions in rat brains: effects on the serotonergic system.
    Neurochemical research, 2000, Volume: 25, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Female; Hydroxyindoleacetic Acid; Male; Maternal Exposure; Melaton

2000
Prenatal melatonin exposure affects luteinizing hormone and hypothalamic and striatal neuropeptide Y in the male rat offspring.
    Neuroscience letters, 2000, Oct-13, Volume: 292, Issue:3

    Topics: Aging; Animals; Corpus Striatum; Female; Gene Expression Regulation, Developmental; Hypothalamus; Lu

2000
Melatonin suppresses lysophosphatidylcholine enhancement of serotonin-induced vasoconstriction in the human umbilical artery.
    Journal of pineal research, 2000, Volume: 29, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Drug Synergism; Female; Free Radical Scavengers; Humans; In

2000
Out-of-season breeding of captive white-tailed deer.
    Theriogenology, 2000, Sep-01, Volume: 54, Issue:4

    Topics: Animals; Breeding; Deer; Drug Combinations; Estrus; Female; Gonadotropins, Equine; Male; Melatonin;

2000
Melatonin counteracts potentiation by homocysteine of KCL-induced vasoconstriction in human umbilical artery: relation to calcium influx.
    Biochemical and biophysical research communications, 2001, Jan-26, Volume: 280, Issue:3

    Topics: Antioxidants; Calcium Signaling; Cardiovascular Diseases; Drug Interactions; Female; Free Radical Sc

2001
Melatonin protects fetal rat brain against oxidative mitochondrial damage.
    Journal of pineal research, 2001, Volume: 30, Issue:1

    Topics: Adenosine Diphosphate; Animals; Brain; Female; Free Radical Scavengers; Free Radicals; Glutathione P

2001
Changes of serum melatonin level and its relationship to feto-placental unit during pregnancy.
    Journal of pineal research, 2001, Volume: 30, Issue:1

    Topics: Adult; Circadian Rhythm; Female; Fetal Growth Retardation; Humans; Melatonin; Pre-Eclampsia; Pregnan

2001
Melatonin secretion after surgery.
    Lancet (London, England), 2001, Feb-17, Volume: 357, Issue:9255

    Topics: Female; Humans; Melatonin; Postoperative Period; Pregnancy; Sleep; Surgical Procedures, Operative

2001
Profile of organ weights and plasma concentrations of melatonin, estradiol and progesterone during gestation and post-parturition periods in female Indian palm squirrel Funambulus pennanti.
    Indian journal of experimental biology, 2000, Volume: 38, Issue:10

    Topics: Animals; Estradiol; Female; Melatonin; Organ Size; Postpartum Period; Pregnancy; Pregnancy, Animal;

2000
Melatonin stimulates glutathione peroxidase activity in human chorion.
    Journal of pineal research, 2001, Volume: 30, Issue:4

    Topics: Abortion, Induced; Chorion; Enzyme Activation; Female; Fetal Growth Retardation; Free Radical Scaven

2001
Ovarian expression of melatonin Mel(1a) receptor mRNA during mouse development.
    Molecular reproduction and development, 2001, Volume: 59, Issue:2

    Topics: Animals; Embryonic and Fetal Development; Female; Gene Expression; Gene Expression Profiling; Hypoth

2001
Melatonin inhibits spontaneous and oxytocin-induced contractions of rat myometrium in vitro.
    Neuro endocrinology letters, 2001, Volume: 22, Issue:3

    Topics: Animals; Apamin; Calcium; Cyclooxygenase Inhibitors; Dinoprost; Female; In Vitro Techniques; Indomet

2001
Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain.
    Journal of pineal research, 2001, Volume: 31, Issue:2

    Topics: Adenosine Diphosphate; Animals; Brain; Brain Injuries; Female; Fetus; Melatonin; Oxidative Stress; O

2001
Melatonin protects against oxidative mitochondrial damage induced in rat placenta by ischemia and reperfusion.
    Journal of pineal research, 2001, Volume: 31, Issue:2

    Topics: Adenosine Diphosphate; Animals; Female; Fetal Growth Retardation; Humans; Melatonin; Mitochondria; O

2001
Melatonin suppresses homocysteine enhancement of serotonin-induced vasoconstriction in the human umbilical artery.
    Journal of pineal research, 2001, Volume: 31, Issue:3

    Topics: Antioxidants; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Ferrous C

2001
Melatonin protects against oxidized low-density lipoprotein-induced inhibition of nitric oxide production in human umbilical artery.
    Journal of pineal research, 2001, Volume: 31, Issue:3

    Topics: Adult; Antioxidants; Arginine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Ass

2001
Influence of melatonin on basal and gonadotropin-stimulated progesterone and estradiol secretion of cultured human granulosa cells and in the superfused granulosa cell system.
    Gynecologic and obstetric investigation, 2001, Volume: 52, Issue:3

    Topics: Adrenergic beta-Agonists; Adult; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Estrad

2001
Effect of prenatal melatonin exposure on gonadotropins and prolactin secretion in male and female rat pups.
    European journal of pharmacology, 2001, Jul-27, Volume: 424, Issue:3

    Topics: Animals; Animals, Newborn; Female; Follicle Stimulating Hormone; Free Radical Scavengers; Gonadotrop

2001
Ontogeny of circadian expression of serotonin N-acetyltransferase mRNA in the rat retina.
    Neuroscience letters, 2002, Jan-04, Volume: 317, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Arylamine N-Acetyltransferase; Biological Clocks; Circadian Rhythm

2002
Nocturnal melatonin and prolactin plasma concentrations in sheep selected for fertility in autumn lambing'.
    Journal of animal science, 2001, Volume: 79, Issue:11

    Topics: Age Factors; Animals; Breeding; Circadian Rhythm; Female; Fertility; Lactation; Melatonin; Pregnancy

2001
Effects of maternal-melatonin treatment on open-field behaviors and hypertensive phenotype in spontaneously hypertensive rats' (SHR) offspring.
    Experimental animals, 2002, Volume: 51, Issue:1

    Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Exploratory Behavior; Female; Hypertension;

2002
Melatonin production in infants.
    Pediatric neurology, 2002, Volume: 26, Issue:5

    Topics: Analysis of Variance; Chi-Square Distribution; Child Development; Female; Humans; Infant; Infant, Ne

2002
Fertility patterns in female mice following treatment with arginine vastocin or melatonin.
    International journal of fertility, 1976, Volume: 21, Issue:1

    Topics: Animals; Estrus; Female; Fertility; Injections, Intraperitoneal; Melatonin; Mice; Pregnancy; Vasotoc

1976
The pineal gland: a model of neuroendocrine regulation.
    Research publications - Association for Research in Nervous and Mental Disease, 1978, Volume: 56

    Topics: Acetyltransferases; Animals; Catecholamines; Cell Separation; Circadian Rhythm; Cyclic AMP; Female;

1978
Maternal-fetal transfer of melatonin in the non-human primate.
    Pediatric research, 1979, Volume: 13, Issue:6

    Topics: Acetylserotonin O-Methyltransferase; Acetyltransferases; Animals; Female; Haplorhini; Macaca mulatta

1979
Brain neurotransmitters and their interaction with the hypothalamo-pituitary-gonadal principles.
    Advances in the biosciences, 1975, Volume: 15

    Topics: Adrenal Cortex; Adrenal Glands; Amygdala; Animals; Atropine; Depression, Chemical; Dopamine; Estrus;

1975
Melatonin secretion decreases during the proestrous stage of the rat estrous cycle.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:1

    Topics: Animals; Castration; Estradiol; Estrus; Female; Melatonin; Norepinephrine; Pineal Gland; Pregnancy;

1978
Ontogenesis of circadian rhythm of melatonin synthesis in pineal gland of rat.
    Journal of neural transmission. Supplementum, 1978, Issue:13

    Topics: Acetyltransferases; Animals; Biological Clocks; Circadian Rhythm; Darkness; Female; Light; Male; Mel

1978
Physiological control of melatonin synthesis and secretion: mechanisms, generating rhythms in melatonin, methoxytryptophol, and arginine vasotocin levels and effects on the pineal of endogenous catecholamines, the estrous cycle, and environmental lighting
    Journal of neural transmission. Supplementum, 1978, Issue:13

    Topics: Animals; Arginine; Circadian Rhythm; Darkness; Estrus; Female; Humans; Indoles; Light; Melatonin; No

1978
Pineal-brain relationship.
    Progress in brain research, 1979, Volume: 52

    Topics: Animals; Brain; Central Nervous System; Choroid Plexus; Corpus Luteum; Diestrus; Estrus; Female; Gon

1979
Melatonin in the maternal and umbilical circulations during human parturition.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:10

    Topics: Circadian Rhythm; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; Melatonin; Pregnan

1979
A possible role of the pineal gland in pregnancy and fertility.
    Progress in brain research, 1979, Volume: 52

    Topics: Animals; Estradiol; Female; Fertility; Fetal Resorption; Light; Litter Size; Luteinizing Hormone; Me

1979
Effect of melatonin administered during the night on reproductive function in the Syrian hamster.
    Endocrinology, 1977, Volume: 101, Issue:2

    Topics: Animals; Circadian Rhythm; Cricetinae; Darkness; Estrus; Female; Light; Male; Melatonin; Mesocricetu

1977
Induced PKU in rats: effects of age and melatonin treatment.
    Pharmacology, biochemistry, and behavior, 1977, Volume: 7, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Female; Humans; Learning; Melatonin

1977
Melatonin induction of gonadal quiescence in pinealectomized Syrian hamsters.
    Science (New York, N.Y.), 1977, Dec-02, Volume: 198, Issue:4320

    Topics: Animals; Cricetinae; Estrus; Female; Follicle Stimulating Hormone; Light; Luteinizing Hormone; Male;

1977
Serum melatonin concentrations during different stages of the annual reproductive cycle in ewes.
    Biology of reproduction, 1978, Volume: 18, Issue:2

    Topics: Anestrus; Animals; Circadian Rhythm; Estrus; Female; Light; Melatonin; Pregnancy; Sheep; Time Factor

1978
Alteration of compensatory ovarian hypertrophy in the hamster by melatonin.
    Life sciences, 1978, Jun-26, Volume: 22, Issue:24

    Topics: Animals; Castration; Cricetinae; Estrus; Female; Functional Laterality; Hypertrophy; Melatonin; Meso

1978
Inhibition of estrous cyclicity in golden hamsters by melatonin administration on the day of proestrus.
    The Journal of experimental zoology, 1979, Volume: 207, Issue:1

    Topics: Animals; Cricetinae; Estrus; Female; Melatonin; Mesocricetus; Pregnancy; Proestrus

1979
Interaction of daily injections and subcutaneous reservoirs of melatonin on the reproductive physiology of female Syrian hamsters.
    Acta endocrinologica, 1979, Volume: 91, Issue:1

    Topics: Animals; Cricetinae; Drug Implants; Estrus; Female; Injections, Subcutaneous; Luteinizing Hormone; M

1979
Pineal serotonin N-acetyltransferase activity in the rat during the estrous cycle and in response to light.
    Biology of reproduction, 1979, Volume: 21, Issue:2

    Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Estrus; Female; Light; Melatonin; Pineal

1979
Pineal melatonin content throughout the hamster estrous cycle.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 162, Issue:1

    Topics: Animals; Circadian Rhythm; Cricetinae; Environment, Controlled; Estrogens; Estrus; Feedback; Female;

1979
Effect of melatonin on induction of ovulation in the light- induced constant estrous-anovulatory syndrome and possible role of the brain serotoninergic system.
    Journal of endocrinological investigation, 1978, Volume: 1, Issue:4

    Topics: Animals; Anovulation; Estrus; Female; Light; Melatonin; Methiothepin; Ovulation; Pineal Gland; Pregn

1978
Some endocrine effects of the pineal gland and melatonin with special reference to reproduction.
    Progress in brain research, 1979, Volume: 52

    Topics: Animals; Castration; Estrus; Female; Hypothalamus; Light; Luteinizing Hormone; Male; Melatonin; Ovul

1979
On the presence of melatonin in pineal glands and plasma of foetal sheep.
    Journal of steroid biochemistry, 1977, Volume: 8, Issue:5

    Topics: Acetylserotonin O-Methyltransferase; Animals; Animals, Newborn; Female; Gestational Age; Melatonin;

1977
Melatonin in amniotic fluid during human parturition.
    British journal of obstetrics and gynaecology, 1978, Volume: 85, Issue:9

    Topics: Amniotic Fluid; Female; Humans; Labor, Obstetric; Melatonin; Pregnancy; Pregnancy Trimester, Third

1978
Transport of maternal[3H]melatonin to suckling rats and the fate of [3H]melatonin in the neonatal rat.
    Endocrinology, 1978, Volume: 102, Issue:2

    Topics: Animal Population Groups; Animals; Animals, Suckling; Female; Melatonin; Milk; Pregnancy; Rats; Trit

1978
Melatonin in the maternal and umbilical circulations during human parturition.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:1

    Topics: Cesarean Section; Female; Fetal Blood; Humans; Labor, Obstetric; Melatonin; Obstetric Labor, Prematu

1979
[The gonadotropic hypothalamus. Its development from the embryonic period to the menopause].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1976, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Dopamine; Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing

1976
Differential localization of antigonadotropic and vasotocic activities in bovine and rat pineal.
    Life sciences, 1976, Sep-01, Volume: 19, Issue:5

    Topics: Animals; Cattle; Female; Lactation; Male; Melatonin; Organ Size; Pineal Gland; Pregnancy; Prostate;

1976
Studies on the duration of the breeding season and photorefractoriness in female ferrets pinealectomized or treated with melatonin.
    The Journal of endocrinology, 1976, Volume: 70, Issue:2

    Topics: Anestrus; Animals; Carnivora; Estrus; Female; Ferrets; Light; Melatonin; Pineal Gland; Pregnancy; Ti

1976
Influence of melatonin, constant light, or blinding on reproductive system of gerbils (Meriones unguiculatus).
    Experientia, 1976, Oct-15, Volume: 32, Issue:10

    Topics: Animals; Blindness; Body Weight; Female; Genitalia; Gerbillinae; Light; Litter Size; Male; Melatonin

1976
[Dynamics of melatonin excretion in women at the end of pregnancy, during normal labor and during the postpartum period].
    Akusherstvo i ginekologiia, 1976, Volume: 5

    Topics: Adult; Female; Humans; Melatonin; Pregnancy

1976
[Dynamics of the serotonin content and melatonin and 5-hydroxy-indoleacetic acid excretion at the end of pregnancy, during normal labor and in labor anomalies].
    Voprosy okhrany materinstva i detstva, 1976, Volume: 21, Issue:11

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Labor, Obstetric; Melatonin; Obstetric Labor Compli

1976
Effect of melatonin on the reproductive systems of male and female Syrian hamsters: a diurnal rhythm in sensitivity to melatonin.
    Endocrinology, 1976, Volume: 99, Issue:6

    Topics: Animals; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Estrus; Female; Follicle St

1976
Endocrine rhythms associated with pineal gland function.
    Advances in experimental medicine and biology, 1975, Volume: 54

    Topics: Acetyltransferases; Adrenal Glands; Animals; Carnivora; Chickens; Circadian Rhythm; Cricetinae; Estr

1975
An analysis of the pineal hydroxyindole-O-methyl transferase rhythm during the estrous cycle of the rat.
    Advances in experimental medicine and biology, 1975, Volume: 54

    Topics: Animals; Carbon Radioisotopes; Cervix Uteri; Circadian Rhythm; Copulation; Darkness; Estrus; Female;

1975
Estrogen secretion and its relation to corpus luteum formation in monkeys (Macaca fascicularis) given melatonin.
    Fertility and sterility, 1975, Volume: 26, Issue:6

    Topics: Animals; Corpus Luteum; Estrogens; Estrus; Female; Hypothalamus; Injections, Subcutaneous; Macaca fa

1975
The effect and site of action of indoleamines on the hypothalamic centers involved in the control of LH release and ovulation in sheep.
    Neuroendocrinology, 1975, Volume: 17, Issue:3

    Topics: Animals; Estrus; Female; Hypothalamus; Luteinizing Hormone; Melatonin; Ovulation; Pregnancy; Seroton

1975
The effect of the pineal gland on ovulation and pregnancy in the rat.
    Biology of reproduction, 1975, Volume: 13, Issue:4

    Topics: Animals; Female; Fetal Resorption; Follicle Stimulating Hormone; Luteinizing Hormone; Melatonin; Org

1975
Proceedings: Melatonin in fetal and maternal ovine plasma.
    Journal of reproduction and fertility, 1976, Volume: 46, Issue:2

    Topics: Animals; Female; Fetal Blood; Melatonin; Pregnancy; Sheep

1976
Maternal transfer of photoperiodic information in Siberian hamsters. V. Effects of melatonin implants are dependent on photoperiod.
    Biology of reproduction, 1992, Volume: 47, Issue:2

    Topics: Animals; Drug Implants; Female; Fetus; Light; Male; Maternal-Fetal Exchange; Melatonin; Organ Size;

1992
Maternal plasma catecholamines in the rhesus macaque during late gestation: effect of photoperiod and timed melatonin infusion.
    Biology of reproduction, 1992, Volume: 47, Issue:4

    Topics: Animals; Catecholamines; Dopamine; Epinephrine; Female; Macaca mulatta; Melatonin; Norepinephrine; P

1992
Effect of melatonin on pulsatile release of luteinizing hormone in female lambs.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1992, Volume: 24, Issue:5

    Topics: Animals; Drug Implants; Estradiol; Feedback; Female; Luteinizing Hormone; Melatonin; Pregnancy; Prog

1992
Influence of melatonin on reproductive behavior in male rats.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:8

    Topics: Animals; Female; Male; Melatonin; Pregnancy; Rats; Rats, Wistar; Sexual Behavior, Animal

1992
Evidence that circadian variations of circulating melatonin levels in fetal and suckling rats are dependent on maternal melatonin transfer.
    Neuroendocrinology, 1992, Volume: 55, Issue:3

    Topics: Animals; Animals, Suckling; Circadian Rhythm; Female; Fetal Blood; Lactation; Maternal-Fetal Exchang

1992
Colic, sleep inertia, melatonin and circannual rhythms.
    Medical hypotheses, 1992, Volume: 38, Issue:3

    Topics: Colic; Crying; Female; Fetus; Geography; Humans; Infant; Infant, Newborn; Maternal-Fetal Exchange; M

1992
Androgenic activity in 15-day-old male rats: role of the maternal pineal gland.
    Biology of reproduction, 1992, Volume: 46, Issue:3

    Topics: Androgens; Androstenedione; Animals; Female; Light; Male; Maternal-Fetal Exchange; Melatonin; Organ

1992
Circadian myometrial and endocrine rhythms in the pregnant rhesus macaque: effects of constant light and timed melatonin infusion.
    American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:6 Pt 1

    Topics: Animals; Circadian Rhythm; Estradiol; Estrogens; Estrone; Female; Hydrocortisone; Macaca mulatta; Me

1991
Effects of different lighting regimes on daily hormonal and behavioural rhythms in the pregnant ewe and sheep fetus.
    The Journal of physiology, 1991, Volume: 442

    Topics: Animals; Circadian Rhythm; Female; Fetal Blood; Fetal Movement; Light; Melatonin; Pregnancy; Pregnan

1991
The ontogeny of central melatonin binding sites in the rat.
    Endocrinology, 1991, Volume: 128, Issue:4

    Topics: Animals; Animals, Newborn; Autoradiography; Brain; Female; Fetus; Gestational Age; Maternal-Fetal Ex

1991
Photoperiod regulation of uterine activity and melatonin rhythms in the pregnant rhesus macaque.
    Biology of reproduction, 1991, Volume: 44, Issue:6

    Topics: Animals; Circadian Rhythm; Female; Labor, Obstetric; Light; Macaca mulatta; Melatonin; Pregnancy; Pr

1991
Prolactin levels in the western spotted skunk: changes during pre- and periimplantation and effects of melatonin and lesions to the anterior hypothalamus.
    Biology of reproduction, 1991, Volume: 44, Issue:6

    Topics: Animals; Embryo Implantation; Embryonic Development; Female; Hypothalamus, Anterior; Melatonin; Meph

1991
Lack of effect of melatonin on myometrial electromyographic activity in the pregnant sheep at 138-142 days gestation (term = 147 days gestation).
    Endocrinology, 1991, Volume: 128, Issue:4

    Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Electromyography; Electrophysiology; Fe

1991
Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat.
    Journal of pineal research, 1991, Volume: 11, Issue:1

    Topics: Animals; Animals, Newborn; Estrus; Female; Luteinizing Hormone; Melatonin; Pineal Gland; Pregnancy;

1991
Serum melatonin during human pregnancy.
    Acta endocrinologica, 1991, Volume: 124, Issue:3

    Topics: Circadian Rhythm; Female; Humans; Melatonin; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimes

1991
Effects of photoperiod on mammary development and concentration of hormones in serum of pregnant dairy heifers.
    Journal of dairy science, 1991, Volume: 74, Issue:1

    Topics: Animals; Cattle; Female; Hormones; Labor, Obstetric; Light; Mammary Glands, Animal; Melatonin; Pregn

1991
[Melatonin levels in maternal plasma before and during delivery, and in fetal and neonatal plasma].
    Nihon Sanka Fujinka Gakkai zasshi, 1991, Volume: 43, Issue:3

    Topics: Circadian Rhythm; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; Melatonin; Pineal

1991
Pineal gland free amino acids and indoles during postnatal development of the rat: correlations in individual glands.
    Journal of pineal research, 1990, Volume: 9, Issue:1

    Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Female; Glutamates; In

1990
Emergence of the diurnal rhythm in plasma melatonin concentrations in newborn lambs delivered to intact or pinealectomized ewes.
    The Journal of endocrinology, 1990, Volume: 125, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Animals, Suckling; Circadian Rhythm; Female; Melatonin; Pine

1990
Melatonin in infants and mothers at delivery and in infants during the first week of life.
    Clinical endocrinology, 1990, Volume: 32, Issue:5

    Topics: Adult; Chromatography, High Pressure Liquid; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Ob

1990
Melatonin but not the ram-effect reactivates quiescent ovarian activity of mid-anestrous ewe.
    Nihon juigaku zasshi. The Japanese journal of veterinary science, 1990, Volume: 52, Issue:4

    Topics: Anestrus; Animals; Estrus; Female; Melatonin; Ovary; Ovulation Induction; Periodicity; Pheromones; P

1990
Interactions between melatonin and prolactin during gestation in mink (Mustela vison).
    Journal of reproduction and fertility, 1990, Volume: 89, Issue:2

    Topics: Animals; Drug Implants; Drug Interactions; Embryo Implantation; Female; Melatonin; Mink; Pregnancy;

1990
Effects of altered photoperiod or maternal melatonin administration on plasma prolactin concentrations in fetal lambs.
    The Journal of endocrinology, 1989, Volume: 122, Issue:3

    Topics: Animals; Female; Fetus; Light; Maternal-Fetal Exchange; Melatonin; Metoclopramide; Pregnancy; Pregna

1989
[Alpha-MSH and pregnancy].
    Zeitschrift fur Hautkrankheiten, 1989, Jul-15, Volume: 64, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; alpha-MSH; Female; Gestational Age; Humans; Melatonin; Pregnancy

1989
Changing responsiveness of luteal cells of the marmoset monkey (Callithrix jacchus) to luteotrophic and luteolytic agents during normal and conception cycles.
    Journal of reproduction and fertility, 1989, Volume: 87, Issue:1

    Topics: Animals; Bucladesine; Callithrix; Chorionic Gonadotropin; Cloprostenol; Corpus Luteum; Corpus Luteum

1989
Effect of isoprenaline on the output of melatonin from fetal and newborn lamb pineal glands in vitro.
    Acta endocrinologica, 1989, Volume: 121, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Female; Isoproterenol; Melatonin; Perfusion; Pineal Gland; Pre

1989
Lesions to the anterior hypothalamus prevent the melatonin-induced lengthening of delayed implantation.
    Endocrinology, 1989, Volume: 125, Issue:6

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Carnivora; Embryo Implantation; Embryo Implantation, Delay

1989
Maternal melatonin treatment influences rates of neonatal development of meadow vole pups.
    Biology of reproduction, 1989, Volume: 40, Issue:3

    Topics: Animals; Arvicolinae; Birth Weight; Energy Intake; Female; Hair; Lactation; Male; Melatonin; Periodi

1989
Fetal prolactin levels respond to a maternal melatonin implant.
    Endocrinology, 1989, Volume: 125, Issue:1

    Topics: Animals; Drug Implants; Female; Fetal Blood; Maternal-Fetal Exchange; Melatonin; Pregnancy; Pregnanc

1989
Maternal transfer of photoperiodic information in Siberian hamsters. II. The nature of the maternal signal, time of signal transfer, and the effect of the maternal signal on peripubertal reproductive development in the absence of photoperiodic input.
    Biology of reproduction, 1989, Volume: 40, Issue:3

    Topics: Aging; Animals; Cricetinae; Darkness; Female; Lactation; Light; Male; Maternal-Fetal Exchange; Melat

1989
Serum and amniotic fluid melatonin during human labor.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:5

    Topics: Adult; Amniotic Fluid; Circadian Rhythm; Female; Humans; Labor, Obstetric; Melatonin; Pregnancy; Rad

1989
Maternal transfer of photoperiodic information in Siberian hamsters. III. Melatonin injections program postnatal reproductive development expressed in constant light.
    Biology of reproduction, 1989, Volume: 41, Issue:1

    Topics: Animals; Cricetinae; Female; Injections; Light; Male; Maternal-Fetal Exchange; Melatonin; Pregnancy;

1989
Maternal pinealectomy abolishes the diurnal rhythm in plasma melatonin concentrations in the fetal sheep and pregnant ewe during late gestation.
    The Journal of endocrinology, 1989, Volume: 120, Issue:3

    Topics: Animals; Circadian Rhythm; Female; Fetal Blood; Gestational Age; Labor, Obstetric; Melatonin; Pineal

1989
Fertility of ewes given either melatonin or progestogen sponges.
    The Veterinary record, 1989, Mar-04, Volume: 124, Issue:9

    Topics: Administration, Intravaginal; Animals; Estrus; Female; Fertility; Gonadotropins, Equine; Melatonin;

1989
Daily administration of melatonin delays rat vaginal opening and disrupts the first estrous cycles: evidence that these effects are synchronized by the onset of light.
    Endocrinology, 1985, Volume: 116, Issue:2

    Topics: Animals; Circadian Rhythm; Estradiol; Estrus; Female; Follicle Stimulating Hormone; Light; Luteinizi

1985
Plasma levels of immunoreactive melatonin, estradiol, progesterone, follicle stimulating hormone, and beta-human chorionic gonadotropin during pregnancy and shortly after parturition in humans.
    Journal of pineal research, 1987, Volume: 4, Issue:1

    Topics: Chorionic Gonadotropin; Estradiol; Female; Fetal Blood; Follicle Stimulating Hormone; Hormones; Huma

1987
Effects of subcutaneous melatonin implants on reproductive seasonality of farmed fallow deer (Dama dama).
    Journal of reproduction and fertility, 1988, Volume: 84, Issue:2

    Topics: Animals; Deer; Drug Implants; Estrus; Female; Lactation; Male; Melatonin; Pregnancy; Reproduction; S

1988
Influence of concentration, duration and route of administration of melatonin on reproductive performance of spring-mated polypay and polypay-cross ewes.
    Journal of animal science, 1988, Volume: 66, Issue:8

    Topics: Administration, Oral; Animals; Drug Implants; Estrus; Female; Melatonin; Ovulation; Pregnancy; Pregn

1988
Effect of maternal pinealectomy and reverse photoperiod on the circadian melatonin rhythm in the sheep and fetus during the last trimester of pregnancy.
    Biology of reproduction, 1988, Volume: 39, Issue:5

    Topics: Animals; Circadian Rhythm; Female; Fetus; Light; Melatonin; Pineal Gland; Pregnancy; Pregnancy, Anim

1988
Iodinated melatonin mimics melatonin action and reveals discrete binding sites in fetal brain.
    FEBS letters, 1988, Feb-08, Volume: 228, Issue:1

    Topics: Animals; Binding Sites; Brain; Cricetinae; Female; Fetus; Hypothalamus; Melatonin; Pineal Gland; Pit

1988
Use of an intraruminal soluble glass bolus containing melatonin for early lamb production.
    The Veterinary record, 1988, Mar-05, Volume: 122, Issue:10

    Topics: Animals; Delayed-Action Preparations; Estrus; Female; Melatonin; Pregnancy; Pregnancy, Animal; Rando

1988
Reduction of the nocturnal rise in pineal melatonin levels in rats exposed to 60-Hz electric fields in utero and for 23 days after birth.
    Life sciences, 1988, Volume: 42, Issue:22

    Topics: Animals; Circadian Rhythm; Electricity; Female; Fetus; Male; Melatonin; Pineal Gland; Pregnancy; Rat

1988
Diurnal rhythms in plasma melatonin concentrations in the fetal sheep and pregnant ewe during late gestation.
    Endocrinology, 1988, Volume: 123, Issue:1

    Topics: Animals; Circadian Rhythm; Female; Fetal Blood; Fetus; Gestational Age; Melatonin; Pregnancy; Pregna

1988
Melatonin and light treatment of ewes for autumn lambing.
    Reproduction, nutrition, developpement, 1988, Volume: 28, Issue:2B

    Topics: Animals; Female; Light; Melatonin; Periodicity; Pregnancy; Pregnancy, Animal; Sheep

1988
Entrainment of hamster pup circadian rhythms by prenatal melatonin injections to the mother.
    The American journal of physiology, 1988, Volume: 255, Issue:3 Pt 2

    Topics: Animals; Circadian Rhythm; Cricetinae; Female; Maternal-Fetal Exchange; Melatonin; Mesocricetus; Mod

1988
Definition of a prenatal sensitive period for maternal-fetal communication of day length.
    The American journal of physiology, 1987, Volume: 253, Issue:6 Pt 1

    Topics: Age Factors; Animals; Cricetinae; Female; Light; Male; Maternal-Fetal Exchange; Melatonin; Periodici

1987
Effect of exercise on puberty, periods and pregnancy.
    The New Zealand medical journal, 1986, Jan-22, Volume: 99, Issue:794

    Topics: Amenorrhea; Body Composition; Body Weight; Estrogens; Female; Gonadotropins, Pituitary; Humans; Hypo

1986
Control of breeding in the mare.
    Equine veterinary journal, 1987, Volume: 19, Issue:2

    Topics: Anestrus; Animals; Estrus; Female; Horses; Light; Melatonin; Pregnancy; Pregnancy, Animal; Progester

1987
Melatonin rhythms in fetal and maternal circulation during pregnancy in sheep.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 1

    Topics: Animals; Circadian Rhythm; Female; Gestational Age; Maternal-Fetal Exchange; Melatonin; Pregnancy; P

1987
Effect of melatonin and removal of pouch young on the seasonality of births in the marsupial possum, Trichosurus vulpecula.
    Journal of reproduction and fertility, 1987, Volume: 80, Issue:1

    Topics: Animals; Female; Labor, Obstetric; Marsupialia; Melatonin; Pregnancy; Pregnancy, Animal; Seasons

1987
Induction and persistence of pituitary and ovarian activity in the out-of-season lactating dairy goat after a treatment combining a skeleton photoperiod, melatonin and the male effect.
    Journal of reproduction and fertility, 1986, Volume: 78, Issue:2

    Topics: Animals; Female; Goats; Lactation; Light; Luteinizing Hormone; Melatonin; Ovary; Ovulation Induction

1986
Melatonin lowers plasma prolactin levels in female red deer (Cervus elaphus).
    Journal of pineal research, 1987, Volume: 4, Issue:1

    Topics: Animals; Deer; Female; Lactation; Light; Melatonin; Pregnancy; Prolactin; Seasons

1987
Time of parturition in rats after melatonin administration or change of photoperiod.
    Journal of reproduction and fertility, 1987, Volume: 80, Issue:2

    Topics: Animals; Female; Gestational Age; Labor, Obstetric; Light; Melatonin; Periodicity; Pregnancy; Rats;

1987
Change in duration of elevated concentrations of melatonin is the major factor in photoperiod response of the tammar, Macropus eugenii.
    Journal of reproduction and fertility, 1986, Volume: 77, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Estrus; Female; Light; Macropodidae; Marsupialia; Melaton

1986
Induction of early breeding in red deer (Cervus elaphus) by melatonin.
    Journal of reproduction and fertility, 1986, Volume: 76, Issue:2

    Topics: Animals; Body Weight; Breeding; Deer; Female; Lactation; Male; Melatonin; Pregnancy; Reproduction; S

1986
Maternal melatonin communicates daylength to the fetus in Djungarian hamsters.
    Endocrinology, 1986, Volume: 119, Issue:6

    Topics: Animals; Cricetinae; Female; Light; Maternal-Fetal Exchange; Melatonin; Periodicity; Pineal Gland; P

1986
Diurnal variations of plasma melatonin concentrations in pregnant or pseudopregnant mink (Mustela vison) maintained under different photoperiods.
    Journal of pineal research, 1986, Volume: 3, Issue:4

    Topics: Animals; Female; Ganglia, Sympathetic; Light; Melatonin; Mink; Periodicity; Pregnancy; Pregnancy, An

1986
Role of the pineal gland in the photoperiodic control of reproductive and non-reproductive functions in mink (Mustela vison).
    Ciba Foundation symposium, 1985, Volume: 117

    Topics: Animals; Circadian Rhythm; Embryo Implantation; Female; Ganglia, Spinal; Light; Melatonin; Mink; Per

1985
Effects of melatonin implants in ram lambs.
    Journal of reproduction and fertility, 1985, Volume: 73, Issue:1

    Topics: Animals; Female; Follicle Stimulating Hormone; Light; Luteinizing Hormone; Male; Maternal-Fetal Exch

1985
Metabolic strategies of pallid bats (Antrozous pallidus) during reproduction.
    Physiology & behavior, 1986, Volume: 36, Issue:1

    Topics: Animals; Body Temperature; Body Temperature Regulation; Chiroptera; Female; Lactation; Light; Melato

1986
Plasma and pineal melatonin levels in female ferrets housed under long or short photoperiods.
    Biology of reproduction, 1986, Volume: 34, Issue:1

    Topics: Animals; Carnivora; Darkness; Female; Ferrets; Hysterectomy; Light; Melatonin; Ovariectomy; Pineal G

1986
Evidence for pineal involvement in timing implantation in the western spotted skunk.
    Journal of pineal research, 1986, Volume: 3, Issue:1

    Topics: Animals; Carnivora; Darkness; Embryo Implantation; Female; Ganglia, Sympathetic; Light; Melatonin; M

1986
Oxytocin release induced by melatonin in the ewe.
    Developmental pharmacology and therapeutics, 1985, Volume: 8, Issue:4

    Topics: Animals; Arginine Vasopressin; Estrus; Female; Melatonin; Oxytocin; Pineal Gland; Pregnancy; Sheep;

1985
Response in peripheral plasma melatonin to photoperiod change and the effects of exogenous melatonin on seasonal quiescence in the tammar, Macropus eugenii.
    Journal of reproduction and fertility, 1985, Volume: 73, Issue:2

    Topics: Anestrus; Animals; Circadian Rhythm; Corpus Luteum; Female; Light; Macropodidae; Marsupialia; Melato

1985
The pineal gland.
    Endeavour, 1970, Volume: 29, Issue:108

    Topics: Animals; Brain Chemistry; Circadian Rhythm; Estrus; Female; Mammals; Melatonin; Norepinephrine; Pine

1970
Neuroendocrine transduction.
    Neurosciences Research Program bulletin, 1971, Volume: 9, Issue:2

    Topics: Animals; Brain; Epinephrine; Female; Heart; Hypothalamus; Liver; Mammary Glands, Animal; Melatonin;

1971
Some antigonadotrophic effects of melatonin-free bovine pineal extracts in rats.
    Acta endocrinologica, 1974, Volume: 76, Issue:3

    Topics: Animals; Castration; Cattle; Chromatography, Gel; Depression, Chemical; Estrus; Female; Hypertrophy;

1974
Changes in the pineal indole metabolism and plasma progesterone levels during the estrous cycle in ewes.
    Steroids and lipids research, 1974, Volume: 5, Issue:5-6

    Topics: Acetylserotonin O-Methyltransferase; Acetyltransferases; Anestrus; Animals; Estrus; Female; Indoles;

1974
Evidence for the placental transfer of 3 H-acetyl-melatonin.
    Nature: New biology, 1972, May-24, Volume: 237, Issue:73

    Topics: Animals; Autoradiography; Biotin; Bone and Bones; Brain Chemistry; Chromatography, Thin Layer; Diges

1972
[Endocrinologic principles of pigmentation disorders due to contraceptives].
    Archiv fur dermatologische Forschung, 1972, Volume: 244

    Topics: Animals; Anura; Contraceptives, Oral; Estrogens; Female; Humans; Hydrocortisone; Melanins; Melanocyt

1972
Inhibition of ovulation by melatonin in the cyclic rat.
    Endocrinology, 1973, Volume: 92, Issue:1

    Topics: Animals; Depression, Chemical; Estrus; Female; Luteinizing Hormone; Melatonin; Ovulation; Pituitary

1973
[Modifications of the estrus cycle in female rats kept in darkness after bilateral removal of the superior cervical ganglia].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1973, Volume: 167, Issue:6

    Topics: Age Factors; Animals; Darkness; Environment, Controlled; Estrus; Female; Ganglia, Autonomic; Melaton

1973
The effects of light and sympathetic innervation to the head on nidation in mink.
    The Journal of experimental zoology, 1974, Volume: 187, Issue:2

    Topics: Animals; Blepharoptosis; Blindness; Embryo Implantation; Female; Ganglia, Autonomic; Genetic Linkage

1974
Effects of estradiol on melatonin and protein synthesis in the rat pineal organ.
    Hormone research, 1974, Volume: 5, Issue:5

    Topics: Animals; Castration; Estradiol; Estrus; Female; Indoles; Leucine; Melatonin; Methyltransferases; Pin

1974
Pineal and gonadal function in the rat following cervical sympathectomy.
    Neuroendocrinology, 1971, Volume: 7, Issue:5

    Topics: Animals; Body Weight; Estrus; Female; Ganglia, Autonomic; Haplorhini; Light; Melatonin; Methyltransf

1971
Effects of melatonin and serotonin on the release of FSH and prolactin.
    Endocrinology, 1971, Volume: 88, Issue:6

    Topics: Analysis of Variance; Animals; Cerebral Ventricles; Chiari-Frommel Syndrome; Depression, Chemical; D

1971
Inhibition of compensatory ovarian hypertrophy in mice by melatonin, 5-hydroxytryptamine and pineal powder.
    The Journal of endocrinology, 1971, Volume: 50, Issue:1

    Topics: Animals; Castration; Estrus; Female; Hypertrophy; Melatonin; Mice; Ovary; Pineal Gland; Pregnancy; S

1971
The effect of noradrenaline, dopamine, 5-hydroxytryptamine and melatonin on milk yield and composition in the rabbit.
    The Journal of endocrinology, 1971, Volume: 50, Issue:3

    Topics: Animals; Caseins; Dopamine; Fats; Female; Lactation; Lactose; Melatonin; Milk; Norepinephrine; Pregn

1971
Inhibition of pitocin-induced contractility by melatonin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 138, Issue:3

    Topics: Animals; Estrus; Female; Humans; Melatonin; Mice; Muscle Contraction; Muscle, Smooth; Oxytocin; Preg

1971
Blockade of ovulation by melatonin.
    Experientia, 1971, Volume: 27, Issue:7

    Topics: Animals; Cerebral Ventricles; Estrus; Female; Injections; Luteinizing Hormone; Melatonin; Ovulation;

1971
[The effect of the pineal hormone, melatonin, on adolescent rats exposed to rhythmic light and dark or to continuous light (author's transl)].
    Journal of neuro-visceral relations, 1971, Volume: 0, Issue:0

    Topics: Adrenal Glands; Animals; Body Weight; Circadian Rhythm; Depression, Chemical; Estrus; Female; Gonado

1971
Medial forebrain bundle lesions: blockade of effects of light on rat gonads and pineal.
    Endocrinology, 1967, Volume: 81, Issue:3

    Topics: Animals; Caudate Nucleus; Darkness; Estrus; Female; Hypothalamus; Light; Melatonin; Ovary; Pineal Gl

1967
Estrous cycle changes after prenatal and neonatal injections of melatonin in normal and androgen-sterilized female rats.
    Neuroendocrinology, 1970, Volume: 6, Issue:1

    Topics: Animals; Animals, Newborn; Estrus; Female; Hypothalamus; Infertility, Female; Melatonin; Ovulation;

1970
Modern views on physiology. XIX. Endocrinology.
    The Practitioner, 1970, Volume: 205, Issue:225

    Topics: Adrenal Glands; Animals; Endocrine Glands; Female; Gastrointestinal Hormones; Gonadal Steroid Hormon

1970
Lack of effects of melatonin administration and pinealectomy on the milk ejection response in the rat.
    Endocrinologia japonica, 1970, Volume: 17, Issue:5

    Topics: Animals; Female; Injections, Subcutaneous; Lactation; Melatonin; Oxytocin; Pineal Gland; Pregnancy;

1970
Central control of the pineal gland: visual pathways.
    Archives of neurology, 1968, Volume: 18, Issue:2

    Topics: Animals; Blindness; Darkness; Environment; Estrus; Female; Light; Melatonin; Mesencephalon; Norepine

1968
Pineal gland, melatonin synthesis, and testicular development in the rat.
    Life sciences, 1969, Jul-01, Volume: 8, Issue:13

    Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Darkness; Eye; Female; Male; Melatonin; Organ S

1969
Reversal of the effect of pinealectomy in female rats by multiple isogeneic pineal transplants.
    Endocrinology, 1965, Volume: 77, Issue:6

    Topics: Animals; Estrus; Female; Melatonin; Pineal Gland; Pregnancy; Rats; Transferases; Transplantation, Ho

1965