melatonin has been researched along with Pneumonia in 13 studies
Pneumonia: Infection of the lung often accompanied by inflammation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "pneumoniae-induced inflammation is necessary for the survival of patients." | 5.72 | Melatonin ameliorates lung cell inflammation and apoptosis caused by Klebsiella pneumoniae via AMP-activated protein kinase. ( Jiang, W; Liu, J; Yang, W; Zhao, X, 2022) |
| "The study aims to compare, through histological and biochemical studies, the effects of quercetin, melatonin and their combination in regulation of immuno-inflammatory mediators and heat shock protein expressions in sodium nitrite induced hypoxia in rat lungs." | 3.85 | Original research paper. Pulmonary prophylactic impact of melatonin and/or quercetin: A novel therapy for inflammatory hypoxic stress in rats. ( Al-Rasheed, NM; Attia, HA; Fadda, L; Mohamed, AM; Sharaf, IA, 2017) |
| "The etiology of neonatal lung injury is complicated." | 2.82 | [Research progress on antioxidant mechanism of melatonin in reducing neonatal lung injury]. ( Chen, L; Zhang, Y, 2022) |
| "pneumoniae-induced inflammation is necessary for the survival of patients." | 1.72 | Melatonin ameliorates lung cell inflammation and apoptosis caused by Klebsiella pneumoniae via AMP-activated protein kinase. ( Jiang, W; Liu, J; Yang, W; Zhao, X, 2022) |
| "But melatonin treatment was found more efficient than SMT treatment." | 1.39 | The protective effect of melatonin and S-methylisothiourea treatments in nitrogen mustard induced lung toxicity in rats. ( Aydin, I; Kenar, L; Korkmaz, A; Kunak, ZI; Macit, E; Onguru, O; Turel, S; Uysal, B; Yaman, H; Yaren, H, 2013) |
| "We recently showed that sleep deprivation (SD) exacerbates existing acute lung inflammation, and that melatonin treatment attenuates it via anti-apoptotic and anti-oxidant action." | 1.38 | Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation. ( Baik, HW; Jo, KJ; Kim, BJ; Kim, DH; Kim, JY; Kim, SP; Lee, KH; Lee, SK; Lee, YD, 2012) |
| "Oral melatonin treatment indicated anti-inflammatory efficacy as evidenced by decreased methacholine sensitivity by 24% and airway obstruction by 28%, reduction in BAL eosinophil (P < 0." | 1.37 | Oral melatonin attenuates lung inflammation and airway hyperreactivity induced by inhalation of aerosolized pancreatic fluid in rats. ( Chen, CF; Reiter, RJ; Wang, D; Yeh, DY, 2011) |
| "The malondialdehyde (MDA) level was determined for the effect of oxidative stress." | 1.35 | Melatonin attenuates lipopolysaccharide-induced acute lung inflammation in sleep-deprived mice. ( Baik, HW; Baik, TK; Kim, BJ; Kim, JY; Kim, OS; Kwak, YJ; Lee, JH; Lee, KH; Lee, SK; Lee, YD; Song, DY, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 6 (46.15) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X | 1 |
| Zhang, Y | 2 |
| Ren, Y | 1 |
| Li, J | 1 |
| Chen, L | 1 |
| Jiang, W | 1 |
| Liu, J | 1 |
| Zhao, X | 1 |
| Yang, W | 1 |
| Niu, Z | 1 |
| Li, R | 1 |
| Mao, K | 1 |
| Luo, P | 1 |
| Geng, W | 1 |
| Xu, J | 1 |
| Liao, Y | 1 |
| Zhong, H | 1 |
| Ma, P | 1 |
| Tan, Q | 1 |
| Xia, H | 1 |
| Duan, L | 1 |
| Song, S | 1 |
| Long, D | 1 |
| Liu, Y | 1 |
| Yang, T | 1 |
| Wu, Y | 1 |
| Jin, Y | 1 |
| Sheikholeslami, S | 1 |
| Aryafar, T | 1 |
| Abedi-Firouzjah, R | 1 |
| Banaei, A | 1 |
| Dorri-Giv, M | 1 |
| Zamani, H | 1 |
| Ataei, G | 1 |
| Majdaeen, M | 1 |
| Farhood, B | 1 |
| Macit, E | 1 |
| Yaren, H | 1 |
| Aydin, I | 1 |
| Kunak, ZI | 1 |
| Yaman, H | 1 |
| Onguru, O | 1 |
| Uysal, B | 1 |
| Korkmaz, A | 1 |
| Turel, S | 1 |
| Kenar, L | 1 |
| Taslidere, E | 1 |
| Esrefoglu, M | 1 |
| Elbe, H | 1 |
| Cetin, A | 1 |
| Ates, B | 1 |
| Wu, HM | 1 |
| Shen, QY | 1 |
| Fang, L | 1 |
| Zhang, SH | 1 |
| Shen, PT | 1 |
| Liu, YJ | 1 |
| Liu, RY | 1 |
| Al-Rasheed, NM | 2 |
| Fadda, L | 1 |
| Attia, HA | 1 |
| Sharaf, IA | 1 |
| Mohamed, AM | 1 |
| Lee, YD | 2 |
| Kim, JY | 3 |
| Lee, KH | 2 |
| Kwak, YJ | 1 |
| Lee, SK | 2 |
| Kim, OS | 1 |
| Song, DY | 1 |
| Lee, JH | 1 |
| Baik, TK | 1 |
| Kim, BJ | 2 |
| Baik, HW | 2 |
| Chen, CF | 1 |
| Wang, D | 1 |
| Reiter, RJ | 1 |
| Yeh, DY | 1 |
| Kim, SP | 1 |
| Kim, DH | 1 |
| Jo, KJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Placebo-controlled Randomized Double-blind Trial of Melatonin in Outpatients With COVID-19 Infection[NCT04784754] | Phase 2 | 0 participants (Actual) | Interventional | 2021-04-01 | Withdrawn (stopped due to lack of subject enrollment) | ||
| A Pilot Placebo-controlled Randomized Double-blind Trial of Melatonin in Outpatients With COVID-19 Infection[NCT04474483] | Phase 2 | 8 participants (Actual) | Interventional | 2020-11-06 | Terminated (stopped due to difficult recruitment and complete first visit in person during thne hight of tne pandemic and later not enough subjects) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for melatonin and Pneumonia
| Article | Year |
|---|---|
[Research progress on antioxidant mechanism of melatonin in reducing neonatal lung injury].
Topics: Antioxidants; Humans; Infant, Newborn; Lung; Lung Injury; Melatonin; Oxidative Stress; Pneumonia | 2022 |
The role of melatonin on radiation-induced pneumonitis and lung fibrosis: A systematic review.
Topics: Animals; Humans; Lung; Lung Neoplasms; Melatonin; Pneumonia; Pulmonary Fibrosis; Radiation Injuries; | 2021 |
11 other studies available for melatonin and Pneumonia
| Article | Year |
|---|---|
Melatonin prevents allergic airway inflammation in epicutaneously sensitized mice.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; | 2021 |
Melatonin ameliorates lung cell inflammation and apoptosis caused by Klebsiella pneumoniae via AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Apoptosis; Humans; Inflammation; Klebsiella Infections; Klebsiella pn | 2022 |
Clinical study of novel coronavirus pneumonia prevention by melatonin.
Topics: COVID-19; Humans; Melatonin; Pandemics; Pneumonia; Reproductive Health; SARS-CoV-2 | 2020 |
An Integrative Transcriptomic and Metabolomic Study Revealed That Melatonin Plays a Protective Role in Chronic Lung Inflammation by Reducing Necroptosis.
Topics: Animals; Biomarkers; Case-Control Studies; Disease Models, Animal; Disease Progression; Female; Gene | 2021 |
The protective effect of melatonin and S-methylisothiourea treatments in nitrogen mustard induced lung toxicity in rats.
Topics: Animals; Chemical Warfare Agents; Interleukin-1beta; Isothiuronium; Lung; Lung Diseases; Male; Mechl | 2013 |
Protective effects of melatonin and quercetin on experimental lung injury induced by carbon tetrachloride in rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Carbon Tetrachloride; Catalase; Disease Models, Animal; Fe | 2014 |
JNK-TLR9 signal pathway mediates allergic airway inflammation through suppressing melatonin biosynthesis.
Topics: Animals; Asthma; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Femal | 2016 |
Original research paper. Pulmonary prophylactic impact of melatonin and/or quercetin: A novel therapy for inflammatory hypoxic stress in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrier Proteins; Cytoprotection; Disease Models, Animal; Drug Th | 2017 |
Melatonin attenuates lipopolysaccharide-induced acute lung inflammation in sleep-deprived mice.
Topics: Analysis of Variance; Animals; Body Weight; Histocytochemistry; In Situ Nick-End Labeling; Lipid Per | 2009 |
Oral melatonin attenuates lung inflammation and airway hyperreactivity induced by inhalation of aerosolized pancreatic fluid in rats.
Topics: Administration, Inhalation; Administration, Oral; Animals; Bronchoalveolar Lavage; Chromatography, H | 2011 |
Oral melatonin attenuates lung inflammation and airway hyperreactivity induced by inhalation of aerosolized pancreatic fluid in rats.
Topics: Administration, Inhalation; Administration, Oral; Animals; Bronchoalveolar Lavage; Chromatography, H | 2011 |
Oral melatonin attenuates lung inflammation and airway hyperreactivity induced by inhalation of aerosolized pancreatic fluid in rats.
Topics: Administration, Inhalation; Administration, Oral; Animals; Bronchoalveolar Lavage; Chromatography, H | 2011 |
Oral melatonin attenuates lung inflammation and airway hyperreactivity induced by inhalation of aerosolized pancreatic fluid in rats.
Topics: Administration, Inhalation; Administration, Oral; Animals; Bronchoalveolar Lavage; Chromatography, H | 2011 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |