Page last updated: 2024-10-19

melatonin and Pinealoma

melatonin has been researched along with Pinealoma in 29 studies

Pinealoma: Neoplasms which originate from pineal parenchymal cells that tend to enlarge the gland and be locally invasive. The two major forms are pineocytoma and the more malignant pineoblastoma. Pineocytomas have moderate cellularity and tend to form rosette patterns. Pineoblastomas are highly cellular tumors containing small, poorly differentiated cells. These tumors occasionally seed the neuroaxis or cause obstructive HYDROCEPHALUS or Parinaud's syndrome. GERMINOMA; CARCINOMA, EMBRYONAL; GLIOMA; and other neoplasms may arise in the pineal region with germinoma being the most common pineal region tumor. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2064; Adams et al., Principles of Neurology, 6th ed, p670)

Research Excerpts

ExcerptRelevanceReference
"Confirmed lesions included pineocytoma WHO grade I (60."3.01Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification. ( De Domenico, P; Gagliardi, F; Garbin, E; Mortini, P; Snider, S, 2023)
"Melatonin rhythm was dramatically reduced for undifferentiated or invasive tumors."1.35Contribution of the daily melatonin profile to diagnosis of tumors of the pineal region. ( Brun, J; Champier, J; Chazot, G; Claustrat, B; Fèvre-Montange, M; Jouvet, A; Leston, J; Mottolese, C; Sindou, M, 2009)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199018 (62.07)18.7374
1990's0 (0.00)18.2507
2000's5 (17.24)29.6817
2010's2 (6.90)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Datta, A1
Das, KK1
G, KK1
Jaiswal, AK1
Kumar, R1
Gagliardi, F1
De Domenico, P1
Garbin, E1
Snider, S1
Mortini, P1
Patel, S1
Rahmani, B1
Gandhi, J1
Seyam, O1
Joshi, G1
Reid, I1
Smith, NL1
Waltzer, WC1
Khan, SA1
Campos, LA1
Bueno, C1
Barcelos, IP1
Halpern, B1
Brito, LC1
Amaral, FG1
Baltatu, OC1
Cipolla-Neto, J1
Slawik, H2
Stoffel, M2
Riedl, L1
Veselý, Z1
Behr, M1
Lehmberg, J1
Pohl, C1
Meyer, B2
Wiegand, M2
Krieg, SM2
Leston, J1
Mottolese, C2
Champier, J2
Jouvet, A2
Brun, J1
Sindou, M1
Chazot, G1
Claustrat, B2
Fèvre-Montange, M2
Mandera, M2
Marcol, W1
Bierzyńska-Macyszyn, G1
Kluczewska, E1
WURTMAN, RJ2
AXELROD, J1
Szathmari, A1
Brisson, C1
Reboul, A1
Fauchon, F1
Cardinali, DP1
Vacas, MI1
Preslock, JP1
Kraft, K1
Edelmann, A1
Entzian, W1
Nocke-Finck, L1
Neuwelt, EA1
Lewy, AJ1
Jan, JE1
Tai, J1
Hahn, G1
Rothstein, RR1
Shaw, KM1
Kennaway, DJ1
McCulloch, G1
Matthews, CD1
Seamark, RF1
Barber, SG1
Smith, JA1
Hughes, RC1
Kappers, JA1
Vorkapic, P1
Waldhauser, F1
Bruckner, R1
Biegelmayer, C1
Schmidbauer, M1
Pendl, G1
Miles, A1
Tidmarsh, SF1
Philbrick, D1
Shaw, DM1
Greisheimer, EM1
Piechowiak, H1
Elfvin, L1
David, M1
Bovier-Lapierre, M1
Jeune, M1
Kammer, H1
Herbst, WP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Melatonin Replacement Therapy Effects on Cardiac Autonomic Activity in Pinealectomized Patients[NCT03885258]Early Phase 15 participants (Actual)Interventional2017-05-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for melatonin and Pinealoma

ArticleYear
Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
    Journal of pineal research, 2023, Volume: 75, Issue:4

    Topics: Brain Neoplasms; Glioma; Humans; Melatonin; Neoplasms, Germ Cell and Embryonal; Pineal Gland; Pineal

2023
Revisiting the pineal gland: a review of calcification, masses, precocious puberty, and melatonin functions.
    The International journal of neuroscience, 2020, Volume: 130, Issue:5

    Topics: Calcinosis; Humans; Melatonin; Pineal Gland; Pinealoma; Puberty, Precocious

2020
[Usefulness of melatonin in the diagnostics and therapy of pineal gland and brain neoplasms].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2003, Volume: 56, Issue:11-12

    Topics: Brain Neoplasms; Circadian Rhythm; Humans; Melatonin; Pineal Gland; Pinealoma

2003
Pineal gland, photoperiodic responses, and puberty.
    Journal of endocrinological investigation, 1984, Volume: 7, Issue:2

    Topics: Animals; Brain Neoplasms; Circadian Rhythm; Female; Humans; Light; Luteinizing Hormone; Male; Melato

1984
The pineal gland: basic implications and clinical correlations.
    Endocrine reviews, 1984,Spring, Volume: 5, Issue:2

    Topics: Adrenal Glands; Animals; Arginine Vasopressin; Brain Neoplasms; Cricetinae; Female; Gonads; Humans;

1984
The pineal gland: a review of the biochemistry, physiology and pharmacological potential of melatonin and other pineal substances.
    Advances in drug research, 1977, Volume: 11

    Topics: Animals; Brain; Brain Diseases; Brain Neoplasms; Calcinosis; Circadian Rhythm; Endocrine Glands; Epi

1977
The pineal gland.
    Journal of the American Medical Women's Association, 1968, Volume: 23, Issue:3

    Topics: Animals; Biological Clocks; Cattle; Chemoreceptor Cells; Humans; Light; Mast Cells; Melatonin; Neopl

1968
[The pineal organ. Anatomy, metabolism, physiology and clinical picture].
    Deutsche medizinische Wochenschrift (1946), 1973, Nov-02, Volume: 98, Issue:44

    Topics: Acid-Base Equilibrium; Adrenal Glands; Animals; Biological Evolution; Circadian Rhythm; Endocrine Sy

1973
[The pineal gland and modern comparative anatomy].
    Lakartidningen, 1974, Sep-04, Volume: 71, Issue:36

    Topics: Animals; Anura; Birds; Child, Preschool; Eye; Fishes; Humans; Lizards; Macaca; Male; Melatonin; Micr

1974

Trials

1 trial available for melatonin and Pinealoma

ArticleYear
Melatonin Therapy Improves Cardiac Autonomic Modulation in Pinealectomized Patients.
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Adolescent; Adult; Autonomic Nervous System; Central Nervous System Depressants; Child; Female; Foll

2020

Other Studies

19 other studies available for melatonin and Pinealoma

ArticleYear
Temporal profile of serum melatonin levels in paediatric pineal tumours subjected to surgery: newer insights.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023, Volume: 39, Issue:9

    Topics: Brain Neoplasms; Child; Circadian Rhythm; Humans; Melatonin; Pineal Gland; Pinealoma; Supratentorial

2023
Prospective Study on Salivary Evening Melatonin and Sleep before and after Pinealectomy in Humans.
    Journal of biological rhythms, 2016, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Circadian Rhythm; Female; Humans; Male; Melatonin; Pineal Gland; Pinealoma; Prosp

2016
Contribution of the daily melatonin profile to diagnosis of tumors of the pineal region.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Child; Circadian Rhythm; Female; Humans

2009
Sleep disturbance after pinealectomy in patients with pineocytoma WHO°I.
    Acta neurochirurgica, 2012, Volume: 154, Issue:8

    Topics: Adult; Circadian Rhythm; Female; Humans; Male; Melatonin; Pineal Gland; Pinealoma; Sleep; Sleep Init

2012
Pineal cysts in childhood.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2003, Volume: 19, Issue:10-11

    Topics: Adolescent; alpha-Fetoproteins; Bradycardia; Child; Child, Preschool; Chorionic Gonadotropin, beta S

2003
DEMONSTRATION OF HYDROXYINDOLE-O-METHYL TRANSFERASE, MELATONIN, AND SEROTONIN IN A METASTATIC PARENCHYMATOUS PINEALOMA.
    Nature, 1964, Dec-26, Volume: 204

    Topics: Carbon Isotopes; Chromatography; Histocytochemistry; Indoles; Melatonin; Neoplasm Metastasis; Pineal

1964
Histological features and expression of enzymes implicated in melatonin synthesis in pineal parenchymal tumours and in cultured tumoural pineal cells.
    Neuropathology and applied neurobiology, 2008, Volume: 34, Issue:3

    Topics: Acetylserotonin O-Methyltransferase; Adult; Aged; Arylalkylamine N-Acetyltransferase; Brain Neoplasm

2008
Suppression of plasma prolactin in a patient with a pinealocytoma.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16, Issue:6

    Topics: Adolescent; Brain Neoplasms; Circadian Rhythm; Growth Hormone; Humans; Hydrocortisone; Hypothalamo-H

1984
Disappearance of plasma melatonin after removal of a neoplastic pineal gland.
    The New England journal of medicine, 1983, May-12, Volume: 308, Issue:19

    Topics: Adolescent; Astrocytoma; Brain Neoplasms; Circadian Rhythm; Gas Chromatography-Mass Spectrometry; Hu

1983
Melatonin replacement therapy in a child with a pineal tumor.
    Journal of child neurology, 2001, Volume: 16, Issue:2

    Topics: Adolescent; Brain Neoplasms; Child; Chronic Disease; Dose-Response Relationship, Drug; Female; Hormo

2001
Plasma melatonin, luteinizing hormone, follicle-stimulating hormone, prolactin, and corticoids in two patients with pinealoma.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Brain Neoplasms; Follicle Stimulating Hormone; Gonadotro

1979
Melatonin as a tumour marker in a patient with pineal tumour.
    British medical journal, 1978, Jul-29, Volume: 2, Issue:6133

    Topics: Adult; Brain Neoplasms; Humans; Male; Melatonin; Methods; Pinealoma

1978
Melatonin as a tumour marker in a patient with pineal tumour.
    British medical journal, 1978, Aug-26, Volume: 2, Issue:6137

    Topics: Adolescent; Adult; Brain Neoplasms; Humans; Male; Melatonin; Pineal Gland; Pinealoma; Radioimmunoass

1978
The mammalian pineal gland, a survey.
    Acta neurochirurgica, 1976, Volume: 34, Issue:1-4

    Topics: Animals; Brain Neoplasms; Circadian Rhythm; History, 19th Century; Humans; Light; Melatonin; Netherl

1976
Serum melatonin levels: a new neurodiagnostic tool in pineal region tumors?
    Neurosurgery, 1987, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Brain Neoplasms; Circadian Rhythm; Female; Humans; Infant; Male; Melatonin; Middl

1987
Diagnostic potential of melatonin analysis in pineal tumors.
    The New England journal of medicine, 1985, Aug-01, Volume: 313, Issue:5

    Topics: Adolescent; Brain Neoplasms; Female; Humans; Melatonin; Pineal Gland; Pinealoma

1985
[Pineal tumors and precocious puberty].
    Lyon medical, 1970, Mar-22, Volume: 223, Issue:12

    Topics: Adolescent; Child; Child, Preschool; Female; Humans; Male; Melatonin; Pinealoma; Puberty, Precocious

1970
Melatonin synthesis by an ectopic pinealoma.
    The New England journal of medicine, 1966, Jun-02, Volume: 274, Issue:22

    Topics: Adolescent; Cerebral Ventricles; Female; Humans; Melatonin; Neurosecretion; Pinealoma; Transferases;

1966
Observations on the relationship of the pineal gland to environmental and biological phenomena.
    Transactions of the American Association of Genito-Urinary Surgeons, 1966, Volume: 58

    Topics: Animals; Child; Child, Preschool; Female; Humans; Male; Melatonin; Neurosecretion; Pineal Gland; Pin

1966