melatonin has been researched along with Pheochromocytoma in 4 studies
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin treatment significantly reduced the mRNA expression of catecholamine synthases, including the rate-limiting enzyme tyrosine hydroxylase (Th), 3,4-dihydroxyphenylalanine decarboxylase and dopamine-β-hydroxylase expressed in PC12 cells." | 1.46 | Melatonin regulates catecholamine biosynthesis by modulating bone morphogenetic protein and glucocorticoid actions. ( Hara, T; Hosoya, T; Inagaki, K; Iwata, N; Komatsubara, M; Otsuka, F; Toma, K; Tsukamoto-Yamauchi, N; Wada, J, 2017) |
| "Melatonin (MLT) has received much attention in recent years due to its direct free radical scavenging and antioxidant properties." | 1.31 | Melatonin regulation of antioxidant enzyme gene expression. ( Antoli, I; Herrera, F; Martin, V; Mayo, JC; Rodriguez, C; Sainz, RM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Komatsubara, M | 1 |
| Hara, T | 1 |
| Hosoya, T | 1 |
| Toma, K | 1 |
| Tsukamoto-Yamauchi, N | 1 |
| Iwata, N | 1 |
| Inagaki, K | 1 |
| Wada, J | 1 |
| Otsuka, F | 1 |
| Mayo, JC | 1 |
| Sainz, RM | 1 |
| Antoli, I | 1 |
| Herrera, F | 1 |
| Martin, V | 1 |
| Rodriguez, C | 1 |
| Ishido, M | 1 |
| Wetterberg, L | 1 |
4 other studies available for melatonin and Pheochromocytoma
| Article | Year |
|---|---|
Melatonin regulates catecholamine biosynthesis by modulating bone morphogenetic protein and glucocorticoid actions.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Bone Morphogenetic Protein 4; Catecholamines; Cel | 2017 |
Melatonin regulation of antioxidant enzyme gene expression.
Topics: Animals; Antioxidants; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplast | 2002 |
Melatonin inhibits maneb-induced aggregation of alpha-synuclein in rat pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; alpha-Synuclein; Animals; Fungicides, Industrial; Maneb; Melatonin; PC12 Ce | 2007 |
Clinical importance of melatonin.
Topics: Adolescent; Adult; Aged; Amniotic Fluid; Breast Neoplasms; Child; Circadian Rhythm; Female; Humans; | 1979 |