melatonin has been researched along with Periodontitis in 24 studies
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In rats with ligature-induced periodontitis, melatonin was administered in drinking water for two weeks." | 9.41 | The Effect of Melatonin on Periodontitis. ( Bábíčková, J; Baňasová, L; Celec, P; Chobodová, P; Janko, J; Konečná, B; Tóthová, Ľ, 2021) |
| "The aim of the current clinical trial was to evaluate if the oral supplementation of melatonin after nonsurgical periodontal therapy (NSPT) determined a better periodontal healing than NSPT alone, in patients affected by untreated severe periodontitis." | 9.34 | Melatonin as host modulating agent supporting nonsurgical periodontal therapy in patients affected by untreated severe periodontitis: A preliminary randomized, triple-blind, placebo-controlled study. ( Longoni, S; Pizzi, I; Sartori, M; Tinto, M; Verga, A, 2020) |
| "We found that adjunctive melatonin supplementation can significantly improve the periodontal status after non-surgical treatment, suggesting that melatonin may be a new adjuvant therapy for periodontitis when non-surgical periodontal treatment alone cannot achieve the desired improvement." | 9.22 | Clinical efficacy of melatonin as adjunctive therapy to non-surgical treatment of periodontitis: a systematic review and meta-analysis. ( Li, L; Lin, S; Liu, RY; Wu, T; Zhang, XT; Zhang, ZT, 2022) |
| "Two main aims of this animal study were to inspect the possible effects of periodontitis on the structure and functions of the kidneys and the therapeutic effectiveness of melatonin." | 8.02 | Melatonin improves periodontitis-induced kidney damage by decreasing inflammatory stress and apoptosis in rats. ( Akyildiz, K; Altin, A; Arabaci, T; Bostan, SA; Emre Kose, T; Kose, O; Kuluslu, G; Kurt Bayrakdar, S; Mercantepe, T; Tumkaya, L; Turker Sener, L; Unver, B; Yilmaz, A, 2021) |
| "The aim of this experimental rat study was to investigate the potential inflammatory effects of periodontitis on cardiac left ventricular tissue and the therapeutic activity of melatonin on these effects." | 7.96 | Melatonin ameliorates periodontitis-related inflammatory stress at cardiac left ventricular tissues in rats. ( Akyıldız, K; Altın, A; Arabacı, T; Köse, O; Köse, TE; Kurt Bayrakdar, S; Mercantepe, T; Tümkaya, L; Türker Sener, L; Yemenoglu, H; Yılmaz, A; Zihni Korkmaz, M, 2020) |
| "Obese and periodontitis demonstrated significantly lower melatonin concentrations when compared with controls, but in obese rats with periodontitis these concentrations were even significantly lower when compared with either periodontitis or obese rats." | 7.88 | Melatonin expression in periodontitis and obesity: An experimental in-vivo investigation. ( Cano, P; Esquifino, AI; Fernández-Mateos, P; González, J; Haugen, HJ; Jiménez-Ortega, V; Sanz, M; Virto, L, 2018) |
| "In the obese-periodontitis group, adjunctive melatonin administration resulted in reduced gingival inflammation and BOP, with significant reductions in probing depth and enhanced bone repair demonstrated by micro-CT (15% reduction in alveolar bone destruction) when compared with the same group treated with adjunctive CHX or the normal-weight rats with either melatonin or CHX." | 7.88 | Melatonin as adjunctive therapy in the treatment of periodontitis associated with obesity. ( Cano, P; Esquifino, AI; Fernández-Mateos, P; González, J; Haugen, HJ; Jiménez-Ortega, V; Sanz, M; Virto, L, 2018) |
| "The aim of this study was to evaluate the effects of melatonin on the oxidative stress in heart tissues after induction of experimental periodontitis in rats." | 7.85 | Antioxidant effects of melatonin in heart tissue after induction of experimental periodontitis in rats. ( Fentoğlu, Ö; Kırzıoğlu, FY; Koçak, A; Özdem, M; Uz, E; Vural, H; Yiğit, A; Yılmaz, HR, 2017) |
| "It was found that radiotherapy increased oxidative stress, the periodontal attachment level and alveolar bone loss, and protective melatonin administration significantly reduced the oxidative parameters and prevented periodontal damage in irradiated rats with experimental periodontitis." | 7.85 | Melatonin prevents radiation-induced oxidative stress and periodontal tissue breakdown in irradiated rats with experimental periodontitis. ( Albayrak, M; Arabaci, T; Erdemci, B; Gedikli, S; Kara, A; Kermen, E; Kizildag, A; Köse, O; Özkal Eminoğlu, D; Özkanlar, S; Zihni, M, 2017) |
| "The aim of this study examines the effect of systemic melatonin administration on proinflammatory cytokine levels, apoptosis, alveolar bone loss (ABL), lipid metabolism, and diabetic control in in rats with diabetes mellitus (DM) and ligature-induced periodontitis." | 7.83 | The Effect of Melatonin on Bone Loss, Diabetic Control, and Apoptosis in Rats With Diabetes With Ligature-Induced Periodontitis. ( Aydemir Turkal, H; Balci Yuce, H; Benli, I; Cayli, S; Karatas, O; Ocakli, S; Pirim Gorgun, E, 2016) |
| "The aim of this study is to evaluate the effects of systemic melatonin treatment on serum oxidative stress index (OSI) and alveolar bone loss (ABL) in rats with diabetes mellitus (DM) and periodontitis." | 7.83 | Effects of Melatonin on Oxidative Stress Index and Alveolar Bone Loss in Diabetic Rats With Periodontitis. ( Arabaci, T; Gedikli, S; Kara, A; Kermen, E; Kizildag, A; Kose, O; Ozkanlar, S; Yemenoglu, H, 2016) |
| "This study reveals that melatonin treatment significantly inhibits regional alveolar bone resorption and contributes to periodontal healing in an experimental periodontitis rat model." | 7.81 | Therapeutic Effects of Melatonin on Alveolar Bone Resorption After Experimental Periodontitis in Rats: A Biochemical and Immunohistochemical Study. ( Arabacı, T; Duman, ŞB; Ibişoğlu, E; Kara, A; Kermen, E; Kızıldağ, A; Köse, O; Özkanlar, S, 2015) |
| "Periodontitis is a chronic infectious disease caused by bacterial irritation." | 5.91 | Melatonin Engineering M2 Macrophage-Derived Exosomes Mediate Endoplasmic Reticulum Stress and Immune Reprogramming for Periodontitis Therapy. ( Cui, Y; He, X; Hong, S; Hu, X; Li, X; Li, Y; Lin, K; Mao, L; Wang, X; Xia, Y, 2023) |
| "In rats with ligature-induced periodontitis, melatonin was administered in drinking water for two weeks." | 5.41 | The Effect of Melatonin on Periodontitis. ( Bábíčková, J; Baňasová, L; Celec, P; Chobodová, P; Janko, J; Konečná, B; Tóthová, Ľ, 2021) |
| "Melatonin is an important antioxidant, and through its anti-inflammatory effects it can control immune responses, oxidative stress, and defense cell infiltration." | 5.39 | Immune modulatory and antioxidant effects of melatonin in experimental periodontitis in rats. ( Akman, S; Canakci, CF; Kalkan, Y; Kara, A; Ozkanlar, S; Tozoglu, S; Tozoglu, U, 2013) |
| "The aim of the current clinical trial was to evaluate if the oral supplementation of melatonin after nonsurgical periodontal therapy (NSPT) determined a better periodontal healing than NSPT alone, in patients affected by untreated severe periodontitis." | 5.34 | Melatonin as host modulating agent supporting nonsurgical periodontal therapy in patients affected by untreated severe periodontitis: A preliminary randomized, triple-blind, placebo-controlled study. ( Longoni, S; Pizzi, I; Sartori, M; Tinto, M; Verga, A, 2020) |
| "We found that adjunctive melatonin supplementation can significantly improve the periodontal status after non-surgical treatment, suggesting that melatonin may be a new adjuvant therapy for periodontitis when non-surgical periodontal treatment alone cannot achieve the desired improvement." | 5.22 | Clinical efficacy of melatonin as adjunctive therapy to non-surgical treatment of periodontitis: a systematic review and meta-analysis. ( Li, L; Lin, S; Liu, RY; Wu, T; Zhang, XT; Zhang, ZT, 2022) |
| "Two main aims of this animal study were to inspect the possible effects of periodontitis on the structure and functions of the kidneys and the therapeutic effectiveness of melatonin." | 4.02 | Melatonin improves periodontitis-induced kidney damage by decreasing inflammatory stress and apoptosis in rats. ( Akyildiz, K; Altin, A; Arabaci, T; Bostan, SA; Emre Kose, T; Kose, O; Kuluslu, G; Kurt Bayrakdar, S; Mercantepe, T; Tumkaya, L; Turker Sener, L; Unver, B; Yilmaz, A, 2021) |
| "The aim of this experimental rat study was to investigate the potential inflammatory effects of periodontitis on cardiac left ventricular tissue and the therapeutic activity of melatonin on these effects." | 3.96 | Melatonin ameliorates periodontitis-related inflammatory stress at cardiac left ventricular tissues in rats. ( Akyıldız, K; Altın, A; Arabacı, T; Köse, O; Köse, TE; Kurt Bayrakdar, S; Mercantepe, T; Tümkaya, L; Türker Sener, L; Yemenoglu, H; Yılmaz, A; Zihni Korkmaz, M, 2020) |
| "Obese and periodontitis demonstrated significantly lower melatonin concentrations when compared with controls, but in obese rats with periodontitis these concentrations were even significantly lower when compared with either periodontitis or obese rats." | 3.88 | Melatonin expression in periodontitis and obesity: An experimental in-vivo investigation. ( Cano, P; Esquifino, AI; Fernández-Mateos, P; González, J; Haugen, HJ; Jiménez-Ortega, V; Sanz, M; Virto, L, 2018) |
| "In the obese-periodontitis group, adjunctive melatonin administration resulted in reduced gingival inflammation and BOP, with significant reductions in probing depth and enhanced bone repair demonstrated by micro-CT (15% reduction in alveolar bone destruction) when compared with the same group treated with adjunctive CHX or the normal-weight rats with either melatonin or CHX." | 3.88 | Melatonin as adjunctive therapy in the treatment of periodontitis associated with obesity. ( Cano, P; Esquifino, AI; Fernández-Mateos, P; González, J; Haugen, HJ; Jiménez-Ortega, V; Sanz, M; Virto, L, 2018) |
| "The aim of this study was to evaluate the effects of melatonin on the oxidative stress in heart tissues after induction of experimental periodontitis in rats." | 3.85 | Antioxidant effects of melatonin in heart tissue after induction of experimental periodontitis in rats. ( Fentoğlu, Ö; Kırzıoğlu, FY; Koçak, A; Özdem, M; Uz, E; Vural, H; Yiğit, A; Yılmaz, HR, 2017) |
| "It was found that radiotherapy increased oxidative stress, the periodontal attachment level and alveolar bone loss, and protective melatonin administration significantly reduced the oxidative parameters and prevented periodontal damage in irradiated rats with experimental periodontitis." | 3.85 | Melatonin prevents radiation-induced oxidative stress and periodontal tissue breakdown in irradiated rats with experimental periodontitis. ( Albayrak, M; Arabaci, T; Erdemci, B; Gedikli, S; Kara, A; Kermen, E; Kizildag, A; Köse, O; Özkal Eminoğlu, D; Özkanlar, S; Zihni, M, 2017) |
| "The aim of this study examines the effect of systemic melatonin administration on proinflammatory cytokine levels, apoptosis, alveolar bone loss (ABL), lipid metabolism, and diabetic control in in rats with diabetes mellitus (DM) and ligature-induced periodontitis." | 3.83 | The Effect of Melatonin on Bone Loss, Diabetic Control, and Apoptosis in Rats With Diabetes With Ligature-Induced Periodontitis. ( Aydemir Turkal, H; Balci Yuce, H; Benli, I; Cayli, S; Karatas, O; Ocakli, S; Pirim Gorgun, E, 2016) |
| "The aim of this study is to evaluate the effects of systemic melatonin treatment on serum oxidative stress index (OSI) and alveolar bone loss (ABL) in rats with diabetes mellitus (DM) and periodontitis." | 3.83 | Effects of Melatonin on Oxidative Stress Index and Alveolar Bone Loss in Diabetic Rats With Periodontitis. ( Arabaci, T; Gedikli, S; Kara, A; Kermen, E; Kizildag, A; Kose, O; Ozkanlar, S; Yemenoglu, H, 2016) |
| "This study reveals that melatonin treatment significantly inhibits regional alveolar bone resorption and contributes to periodontal healing in an experimental periodontitis rat model." | 3.81 | Therapeutic Effects of Melatonin on Alveolar Bone Resorption After Experimental Periodontitis in Rats: A Biochemical and Immunohistochemical Study. ( Arabacı, T; Duman, ŞB; Ibişoğlu, E; Kara, A; Kermen, E; Kızıldağ, A; Köse, O; Özkanlar, S, 2015) |
| "The results revealed that increased serum AST, ALT and BUN levels following periodontitis are ameliorated with melatonin treatment." | 3.80 | Multi-organ injuries caused by lipopolysaccharide-induced periodontal inflammation in rats: role of melatonin. ( Acikgoz, S; Akpolat, M; Baba, F; Cengiz, MI; Gulle, K; Kurcer, Z, 2014) |
| "Periodontitis is a chronic infectious disease caused by bacterial irritation." | 1.91 | Melatonin Engineering M2 Macrophage-Derived Exosomes Mediate Endoplasmic Reticulum Stress and Immune Reprogramming for Periodontitis Therapy. ( Cui, Y; He, X; Hong, S; Hu, X; Li, X; Li, Y; Lin, K; Mao, L; Wang, X; Xia, Y, 2023) |
| " This study compared the treatment outcome of SRP and its combination with Er:YAG laser and/or photobiomodulation on patients with severe periodontitis." | 1.72 | Effectiveness of Er:YAG Laser Combined with Photobiomodulation on Periodontitis Based on 3-month Observation. ( Li, H; Wang, B; Yang, B; Zhang, P, 2022) |
| "Melatonin is an important antioxidant, and through its anti-inflammatory effects it can control immune responses, oxidative stress, and defense cell infiltration." | 1.39 | Immune modulatory and antioxidant effects of melatonin in experimental periodontitis in rats. ( Akman, S; Canakci, CF; Kalkan, Y; Kara, A; Ozkanlar, S; Tozoglu, S; Tozoglu, U, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 10 (41.67) | 24.3611 |
| 2020's | 12 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, RY | 1 |
| Li, L | 1 |
| Zhang, ZT | 1 |
| Wu, T | 1 |
| Lin, S | 1 |
| Zhang, XT | 1 |
| Yang, B | 1 |
| Li, H | 1 |
| Zhang, P | 1 |
| Wang, B | 1 |
| Caballero, N | 1 |
| Nieto, MA | 1 |
| Suarez-Zamora, DA | 1 |
| Moreno, S | 1 |
| Remolina, CI | 1 |
| Durán, D | 1 |
| Vega, D | 1 |
| Rodríguez-Urrego, PA | 1 |
| Gómez, CP | 1 |
| Rojas, DP | 1 |
| Ramírez, A | 1 |
| Martínez, O | 1 |
| Baldión-Elorza, AM | 1 |
| Hernández, LJ | 1 |
| Quintero, J | 1 |
| Budhiraja, S | 1 |
| Tarai, B | 1 |
| Jain, D | 1 |
| Aggarwal, M | 2 |
| Indrayan, A | 1 |
| Das, P | 1 |
| Mishra, RS | 1 |
| Bali, S | 1 |
| Mahajan, M | 1 |
| Kirtani, J | 1 |
| Tickoo, R | 1 |
| Soni, P | 1 |
| Nangia, V | 1 |
| Lall, A | 1 |
| Kishore, N | 1 |
| Jain, A | 1 |
| Singh, O | 1 |
| Singh, N | 1 |
| Kumar, A | 1 |
| Saxena, P | 1 |
| Dewan, A | 1 |
| Aggarwal, R | 1 |
| Mehra, M | 1 |
| Jain, M | 1 |
| Nakra, V | 1 |
| Sharma, BD | 1 |
| Pandey, PK | 1 |
| Singh, YP | 1 |
| Arora, V | 2 |
| Jain, S | 2 |
| Chhabra, R | 1 |
| Tuli, P | 1 |
| Boobna, V | 1 |
| Joshi, A | 1 |
| Gupta, R | 1 |
| Aneja, P | 1 |
| Dhall, S | 1 |
| Chugh, IM | 1 |
| Garg, S | 1 |
| Mittal, V | 1 |
| Gupta, A | 3 |
| Jyoti, B | 1 |
| Sharma, P | 1 |
| Bhasin, P | 1 |
| Singhal, RK | 1 |
| Bhasin, A | 1 |
| Vardani, A | 1 |
| Pal, V | 1 |
| Pande, DG | 1 |
| Gulati, T | 1 |
| Nayar, S | 1 |
| Kalra, S | 1 |
| Garg, M | 1 |
| Pande, R | 1 |
| Bag, P | 1 |
| Sharma, J | 1 |
| Handoo, A | 1 |
| Burman, P | 1 |
| Gupta, AK | 1 |
| Choudhary, PN | 1 |
| Gupta, P | 2 |
| Joshi, S | 1 |
| Tayal, N | 1 |
| Gupta, M | 1 |
| Khanna, A | 1 |
| Kishore, S | 1 |
| Sahay, S | 1 |
| Dang, R | 1 |
| Mishra, N | 1 |
| Sekhri, S | 1 |
| Srivastava, RC | 1 |
| Agrawal, MB | 1 |
| Mathur, M | 1 |
| Banwari, A | 1 |
| Khetarpal, S | 1 |
| Pandove, S | 1 |
| Bhasin, D | 1 |
| Singh, H | 1 |
| Midha, D | 1 |
| Bhutani, A | 1 |
| Kaur, M | 1 |
| Singh, A | 1 |
| Sharma, S | 1 |
| Singla, K | 1 |
| Sagar, V | 1 |
| Dixit, A | 1 |
| Bajpai, R | 1 |
| Chachra, V | 1 |
| Tyagi, P | 1 |
| Saxena, S | 1 |
| Uniyal, B | 1 |
| Belwal, S | 1 |
| Aier, I | 1 |
| Singhal, M | 1 |
| Khaduri, A | 1 |
| Du, Z | 1 |
| Liang, S | 1 |
| Li, Y | 2 |
| Zhang, J | 1 |
| Yu, Y | 1 |
| Xu, Q | 1 |
| Sun, Z | 1 |
| Duan, J | 1 |
| Cao, N | 1 |
| Hu, C | 1 |
| Xia, B | 1 |
| He, Y | 1 |
| Huang, J | 1 |
| Yuan, Z | 1 |
| Deng, J | 1 |
| Duan, P | 1 |
| Liu, Q | 1 |
| Guo, S | 1 |
| Huang, Y | 1 |
| Wei, X | 1 |
| Liu, L | 1 |
| Huo, F | 1 |
| Huang, P | 1 |
| Wu, Y | 1 |
| Tian, W | 1 |
| Wang, C | 2 |
| Wang, L | 2 |
| Wang, X | 3 |
| Cao, Z | 2 |
| Cui, Y | 1 |
| Hong, S | 1 |
| Xia, Y | 1 |
| Li, X | 1 |
| He, X | 1 |
| Hu, X | 1 |
| Lin, K | 1 |
| Mao, L | 1 |
| Tinto, M | 1 |
| Sartori, M | 1 |
| Pizzi, I | 1 |
| Verga, A | 1 |
| Longoni, S | 1 |
| Köse, O | 5 |
| Kurt Bayrakdar, S | 2 |
| Akyıldız, K | 2 |
| Altın, A | 2 |
| Arabacı, T | 5 |
| Yemenoglu, H | 2 |
| Zihni Korkmaz, M | 1 |
| Köse, TE | 1 |
| Türker Sener, L | 2 |
| Mercantepe, T | 2 |
| Tümkaya, L | 2 |
| Yılmaz, A | 2 |
| Unver, B | 1 |
| Bostan, SA | 1 |
| Emre Kose, T | 1 |
| Kuluslu, G | 1 |
| Konečná, B | 1 |
| Chobodová, P | 1 |
| Janko, J | 1 |
| Baňasová, L | 1 |
| Bábíčková, J | 1 |
| Celec, P | 1 |
| Tóthová, Ľ | 1 |
| Lu, X | 1 |
| Yu, S | 1 |
| Chen, G | 1 |
| Zheng, W | 1 |
| Peng, J | 1 |
| Huang, X | 1 |
| Chen, L | 1 |
| Şehirli, AÖ | 1 |
| Aksoy, U | 1 |
| Koca-Ünsal, RB | 1 |
| Sayıner, S | 1 |
| Corbella, S | 1 |
| Calciolari, E | 1 |
| Alberti, A | 1 |
| Donos, N | 1 |
| Francetti, L | 1 |
| Özdem, M | 1 |
| Kırzıoğlu, FY | 1 |
| Yılmaz, HR | 1 |
| Vural, H | 1 |
| Fentoğlu, Ö | 1 |
| Uz, E | 1 |
| Koçak, A | 1 |
| Yiğit, A | 1 |
| Renn, TY | 1 |
| Huang, YK | 1 |
| Feng, SW | 1 |
| Wang, HW | 1 |
| Lee, WF | 1 |
| Lin, CT | 1 |
| Burnouf, T | 1 |
| Chen, LY | 1 |
| Kao, PF | 1 |
| Chang, HM | 1 |
| Virto, L | 2 |
| Haugen, HJ | 2 |
| Fernández-Mateos, P | 2 |
| Cano, P | 2 |
| González, J | 2 |
| Jiménez-Ortega, V | 2 |
| Esquifino, AI | 2 |
| Sanz, M | 2 |
| Gulle, K | 1 |
| Akpolat, M | 1 |
| Kurcer, Z | 1 |
| Cengiz, MI | 1 |
| Baba, F | 1 |
| Acikgoz, S | 1 |
| Kermen, E | 3 |
| Özkanlar, S | 4 |
| Kara, A | 4 |
| Kızıldağ, A | 3 |
| Duman, ŞB | 1 |
| Ibişoğlu, E | 1 |
| Balci Yuce, H | 1 |
| Karatas, O | 1 |
| Aydemir Turkal, H | 1 |
| Pirim Gorgun, E | 1 |
| Ocakli, S | 1 |
| Benli, I | 1 |
| Cayli, S | 1 |
| Gedikli, S | 2 |
| Erdemci, B | 1 |
| Özkal Eminoğlu, D | 1 |
| Zihni, M | 1 |
| Albayrak, M | 1 |
| Akman, S | 1 |
| Tozoglu, U | 1 |
| Kalkan, Y | 1 |
| Canakci, CF | 1 |
| Tozoglu, S | 1 |
| Cutando, A | 1 |
| Galindo, P | 2 |
| Gómez-Moreno, G | 2 |
| Arana, C | 2 |
| Bolaños, J | 2 |
| Acuña-Castroviejo, D | 2 |
| Wang, HL | 2 |
| Cutando-Soriano, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is Dietary Melatonin Supplementation a Viable Adjunctive Therapy for Chronic Periodontitis? A Preliminary Randomized Clinical Trial.[NCT03368430] | Phase 4 | 74 participants (Actual) | Interventional | 2016-07-04 | Completed | ||
| Evaluation of Injectable Beta- Tricalcium Phosphate as an Occlusive Barrier Membrane in Treatment of Grade ii Furcation Involvement (Clinical and Radiographic Study)[NCT04443972] | 14 participants (Actual) | Interventional | 2018-04-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for melatonin and Periodontitis
| Article | Year |
|---|---|
Clinical efficacy of melatonin as adjunctive therapy to non-surgical treatment of periodontitis: a systematic review and meta-analysis.
Topics: Humans; Melatonin; Periodontitis; Treatment Outcome | 2022 |
Beneficial Effects of Melatonin on Periodontitis Management: Far More Than Oral Cavity.
Topics: Antioxidants; Humans; Melatonin; Periodontitis; Quality of Life | 2022 |
Beneficial Effects of Melatonin on Periodontitis Management: Far More Than Oral Cavity.
Topics: Antioxidants; Humans; Melatonin; Periodontitis; Quality of Life | 2022 |
Beneficial Effects of Melatonin on Periodontitis Management: Far More Than Oral Cavity.
Topics: Antioxidants; Humans; Melatonin; Periodontitis; Quality of Life | 2022 |
Beneficial Effects of Melatonin on Periodontitis Management: Far More Than Oral Cavity.
Topics: Antioxidants; Humans; Melatonin; Periodontitis; Quality of Life | 2022 |
Insight into the roles of melatonin in bone tissue and bone‑related diseases (Review).
Topics: Animals; Bone and Bones; Dose-Response Relationship, Drug; Female; Humans; Melatonin; Osteoarthritis | 2021 |
Systematic review and meta-analysis on the adjunctive use of host immune modulators in non-surgical periodontal treatment in healthy and systemically compromised patients.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Chronic Disea | 2021 |
2 trials available for melatonin and Periodontitis
| Article | Year |
|---|---|
Melatonin as host modulating agent supporting nonsurgical periodontal therapy in patients affected by untreated severe periodontitis: A preliminary randomized, triple-blind, placebo-controlled study.
Topics: Administration, Oral; Female; Humans; Male; Melatonin; Middle Aged; Periodontitis | 2020 |
The Effect of Melatonin on Periodontitis.
Topics: Animals; Antioxidants; Biomarkers; Disease Models, Animal; Humans; Inflammation; Male; Melatonin; Mi | 2021 |
18 other studies available for melatonin and Periodontitis
| Article | Year |
|---|---|
Effectiveness of Er:YAG Laser Combined with Photobiomodulation on Periodontitis Based on 3-month Observation.
Topics: Humans; Lasers, Solid-State; Matrix Metalloproteinase 8; Melatonin; Periodontitis; Root Planing | 2022 |
Topics: AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Apoptosis; Asthenozoospermia; Calcium; eI | 2022 |
Melatonin Engineering M2 Macrophage-Derived Exosomes Mediate Endoplasmic Reticulum Stress and Immune Reprogramming for Periodontitis Therapy.
Topics: Animals; Endoplasmic Reticulum Stress; Exosomes; Humans; Inflammation; Macrophages; Melatonin; Perio | 2023 |
Melatonin ameliorates periodontitis-related inflammatory stress at cardiac left ventricular tissues in rats.
Topics: Alveolar Bone Loss; Animals; Antioxidants; Male; Melatonin; Periodontitis; Rats; Rats, Sprague-Dawle | 2020 |
Melatonin improves periodontitis-induced kidney damage by decreasing inflammatory stress and apoptosis in rats.
Topics: Alveolar Bone Loss; Animals; Apoptosis; Disease Models, Animal; Kidney; Male; Melatonin; Oxidative S | 2021 |
Role of NLRP3 inflammasome in COVID-19 and periodontitis: Possible protective effect of melatonin.
Topics: COVID-19; Humans; Inflammasomes; Melatonin; NLR Family, Pyrin Domain-Containing 3 Protein; Periodont | 2021 |
Antioxidant effects of melatonin in heart tissue after induction of experimental periodontitis in rats.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Heart; Male; Melatonin; Oxidative Stress; Periodonti | 2017 |
Prophylactic supplement with melatonin successfully suppresses the pathogenesis of periodontitis through normalizing RANKL/OPG ratio and depressing the TLR4/MyD88 signaling pathway.
Topics: Animals; Antioxidants; Male; Melatonin; Myeloid Differentiation Factor 88; Osteoprotegerin; Periodon | 2018 |
Melatonin expression in periodontitis and obesity: An experimental in-vivo investigation.
Topics: Alveolar Bone Loss; Animals; Dental Health Surveys; Immunoassay; Male; Melatonin; Obesity; Periodont | 2018 |
Melatonin as adjunctive therapy in the treatment of periodontitis associated with obesity.
Topics: Animals; Chlorhexidine; Melatonin; Obesity; Periodontitis; Rats; Rats, Wistar | 2018 |
Multi-organ injuries caused by lipopolysaccharide-induced periodontal inflammation in rats: role of melatonin.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatinine; Female; | 2014 |
Therapeutic Effects of Melatonin on Alveolar Bone Resorption After Experimental Periodontitis in Rats: A Biochemical and Immunohistochemical Study.
Topics: Alkaline Phosphatase; Alveolar Bone Loss; Animals; Antioxidants; Bone Remodeling; Calcium; Collagen | 2015 |
The Effect of Melatonin on Bone Loss, Diabetic Control, and Apoptosis in Rats With Diabetes With Ligature-Induced Periodontitis.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Ligation; Male; Melatonin; Periodontitis; Rats; | 2016 |
Effects of Melatonin on Oxidative Stress Index and Alveolar Bone Loss in Diabetic Rats With Periodontitis.
Topics: Alveolar Bone Loss; Animals; Antioxidants; Diabetes Mellitus, Experimental; Melatonin; Oxidative Str | 2016 |
Melatonin prevents radiation-induced oxidative stress and periodontal tissue breakdown in irradiated rats with experimental periodontitis.
Topics: Animals; Antioxidants; Disease Models, Animal; Interleukin-1beta; Male; Melatonin; Oxidative Stress; | 2017 |
Immune modulatory and antioxidant effects of melatonin in experimental periodontitis in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Immunomodulation; Male; Melatonin; Periodontitis; Rat | 2013 |
Relationship between salivary melatonin and severity of periodontal disease.
Topics: Adolescent; Adult; Aged; Antioxidants; Disease Progression; Female; Free Radical Scavengers; Humans; | 2006 |
Melatonin expression in periodontal disease.
Topics: Case-Control Studies; Female; Flow Cytometry; Humans; Killer Cells, Natural; Lymphocyte Count; Male; | 2007 |