Page last updated: 2024-10-19

melatonin and Parodontosis

melatonin has been researched along with Parodontosis in 12 studies

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the effects of melatonin (ME) on insulin resistance (IR) and signaling (IS), proinflammatory cytokine levels, and lipid profiles in pinealectomyzed (PNX) rats with periodontal disease (PD)."7.88Melatonin promotes reduction in TNF levels and improves the lipid profile and insulin sensitivity in pinealectomized rats with periodontal disease. ( Belardi, BE; Chiba, FY; Marani, F; Mattera, MSLC; Pereira, RF; Pinheiro, BCES; Santos, RMD; Sumida, DH; Tessarin, GWL; Tsosura, TVS, 2018)
"Melatonin is a hormone synthesised and secreted by the pineal gland and other organs."6.55Melatonin: A Review of Its Potential Functions and Effects on Dental Diseases. ( González-Cantalapiedra, A; López-Peña, M; Muñoz, F; Permuy, M, 2017)
"This study aimed to investigate the effects of melatonin (ME) on insulin resistance (IR) and signaling (IS), proinflammatory cytokine levels, and lipid profiles in pinealectomyzed (PNX) rats with periodontal disease (PD)."3.88Melatonin promotes reduction in TNF levels and improves the lipid profile and insulin sensitivity in pinealectomized rats with periodontal disease. ( Belardi, BE; Chiba, FY; Marani, F; Mattera, MSLC; Pereira, RF; Pinheiro, BCES; Santos, RMD; Sumida, DH; Tessarin, GWL; Tsosura, TVS, 2018)
" Melatonin level was significantly reduced in patients with periodontal diseases suggesting melatonin could be applied as a potential "perioceutics" treatment of periodontal diseases."3.83Melatonin Receptor Agonists as the "Perioceutics" Agents for Periodontal Disease through Modulation of Porphyromonas gingivalis Virulence and Inflammatory Response. ( He, ZY; Liang, JP; Song, ZC; Zhang, X; Zhou, W; Zhu, CL, 2016)
"Melatonin has improved the inflammatory response in periodontal disease, dental surgeries, and mucositis of head and neck oncologic irradiated patients."2.82Melatonin as an adjunctive treatment on dental procedures: A systematic review. ( Cantiga-Silva, C; Cintra, LTA; de Oliveira, PHC; Faria, FD; Lemos, CAA; Pellizzer, EP, 2022)
"Melatonin is a hormone synthesised and secreted by the pineal gland and other organs."2.55Melatonin: A Review of Its Potential Functions and Effects on Dental Diseases. ( González-Cantalapiedra, A; López-Peña, M; Muñoz, F; Permuy, M, 2017)
"Melatonin has powerful antioxidant effects, functions in an immunomodulatory role, may protect against certain cancers, delays some age-related processes, stimulates the synthesis of type I collagen fibers, and promotes bone formation."2.44Melatonin: potential functions in the oral cavity. ( Acuña-Castroviejo, D; Arana, C; Cutando, A; Gómez-Moreno, G; Reiter, RJ, 2007)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's8 (66.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
de Oliveira, PHC1
Lemos, CAA1
Cantiga-Silva, C1
Faria, FD1
Cintra, LTA1
Pellizzer, EP1
Permuy, M1
López-Peña, M1
González-Cantalapiedra, A1
Muñoz, F1
Carpentieri, AR1
Peralta Lopez, ME1
Aguilar, J1
Solá, VM1
Santos, RMD1
Marani, F1
Chiba, FY1
Mattera, MSLC1
Tsosura, TVS1
Tessarin, GWL1
Pereira, RF1
Belardi, BE1
Pinheiro, BCES1
Sumida, DH1
Cutando, A5
López-Valverde, A2
Gómez-de-Diego, R1
Arias-Santiago, S1
de Vicente-Jiménez, J1
de Diego, RG1
de Vicente, J1
Reiter, R1
Fernández, MH1
Ferrera, MJ3
Najeeb, S1
Khurshid, Z1
Zohaib, S1
Zafar, MS1
Zhou, W1
Zhang, X1
Zhu, CL1
He, ZY1
Liang, JP1
Song, ZC1
Gómez-Moreno, G3
Guardia, J1
Reiter, RJ2
Villalba, J1
Escames, G1
Acuña-Castroviejo, D2
Arana, C1
Czesnikiewicz-Guzik, M1
Konturek, SJ1
Loster, B1
Wisniewska, G1
Majewski, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Dietary Melatonin Supplementation a Viable Adjunctive Therapy for Chronic Periodontitis? A Preliminary Randomized Clinical Trial.[NCT03368430]Phase 474 participants (Actual)Interventional2016-07-04Completed
The Effectiveness of Melatonin in Prevention of Radiation-induced Oral Mucositis[NCT03833570]Phase 240 participants (Actual)Interventional2018-01-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for melatonin and Parodontosis

ArticleYear
Melatonin as an adjunctive treatment on dental procedures: A systematic review.
    Oral diseases, 2022, Volume: 28, Issue:7

    Topics: Humans; Melatonin; Oral Health; Periodontal Diseases

2022
Melatonin: A Review of Its Potential Functions and Effects on Dental Diseases.
    International journal of molecular sciences, 2017, Apr-19, Volume: 18, Issue:4

    Topics: Animals; Antioxidants; Dental Implants; Humans; Melatonin; Periodontal Diseases; Stomatognathic Dise

2017
Melatonin and periodontal tissues: Molecular and clinical perspectives.
    Pharmacological research, 2017, Volume: 125, Issue:Pt B

    Topics: Animals; Bone and Bones; Dental Implants; Diabetes Mellitus; Humans; Melatonin; Mental Disorders; Mo

2017
Therapeutic potential of melatonin in oral medicine and periodontology.
    The Kaohsiung journal of medical sciences, 2016, Volume: 32, Issue:8

    Topics: Animals; Bone Regeneration; Humans; Melatonin; Oral Medicine; Osseointegration; Periodontal Diseases

2016
Melatonin in diseases of the oral cavity.
    Oral diseases, 2010, Volume: 16, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Candida albicans; Candidiasis, Oral; Dental Caries;

2010
Melatonin: potential functions in the oral cavity.
    Journal of periodontology, 2007, Volume: 78, Issue:6

    Topics: Antioxidants; Humans; Melatonin; Mouth Diseases; Osteogenesis; Oxidative Stress; Periodontal Disease

2007
Melatonin and its role in oxidative stress related diseases of oral cavity.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58 Suppl 3

    Topics: Antioxidants; Humans; Inflammation; Melatonin; Mouth Diseases; Oxidative Stress; Periodontal Disease

2007

Other Studies

5 other studies available for melatonin and Parodontosis

ArticleYear
Melatonin promotes reduction in TNF levels and improves the lipid profile and insulin sensitivity in pinealectomized rats with periodontal disease.
    Life sciences, 2018, Nov-15, Volume: 213

    Topics: Animals; Blood Glucose; Cytokines; Insulin; Insulin Resistance; Lipids; Male; Melatonin; Periodontal

2018
Effect of gingival application of melatonin on alkaline and acid phosphatase, osteopontin and osteocalcin in patients with diabetes and periodontal disease.
    Medicina oral, patologia oral y cirugia bucal, 2013, Jul-01, Volume: 18, Issue:4

    Topics: Acid Phosphatase; Administration, Topical; Adult; Aged; Alkaline Phosphatase; Cross-Sectional Studie

2013
Effect of topical application of melatonin to the gingiva on salivary osteoprotegerin, RANKL and melatonin levels in patients with diabetes and periodontal disease.
    Odontology, 2014, Volume: 102, Issue:2

    Topics: Administration, Topical; Adult; Aged; Diabetes Mellitus; Female; Gingiva; Humans; Male; Melatonin; M

2014
Melatonin Receptor Agonists as the "Perioceutics" Agents for Periodontal Disease through Modulation of Porphyromonas gingivalis Virulence and Inflammatory Response.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biofilms; Cells, Cultured; Fibroblasts; Ge

2016
Relationship between salivary melatonin levels and periodontal status in diabetic patients.
    Journal of pineal research, 2003, Volume: 35, Issue:4

    Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Interleukin-2; Male; Melatonin

2003