melatonin has been researched along with Pain, Chronic in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Melatonin (MT) has a good analgesic effect in many diseases, including fibromyalgia, neuropathic pain, chronic headache, and burn pain, with very low acute toxicity and side effects." | 8.12 | Melatonin Abates TMJOA Chronic Pain by MT ( Feng, Y; Hu, S; Jiang, H; Ke, J; Li, H; Liu, W; Liu, X; Long, X, 2022) |
| "Chronic pain is prevalent, and approximately half of patients with chronic pain experience sleep disturbance." | 6.94 | Phase II double-blind randomised controlled trial of exogenous administration of melatonin in chronic pain (DREAM-CP): a study protocol. ( Adam, R; Columb, M; Galley, H; Kanakarajan, S; Onyeakazi, U, 2020) |
| "In this study, chronic pain was induced by spared nerve injury model (SNI) for 4 weeks." | 5.48 | Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis. ( Li, C; Liu, M; Ma, H; Mu, N; Shi, Z; Wang, Y; Yang, J; Yang, Z; Yin, Y; Yu, L, 2018) |
| " Melatonin (MT) has a good analgesic effect in many diseases, including fibromyalgia, neuropathic pain, chronic headache, and burn pain, with very low acute toxicity and side effects." | 4.12 | Melatonin Abates TMJOA Chronic Pain by MT ( Feng, Y; Hu, S; Jiang, H; Ke, J; Li, H; Liu, W; Liu, X; Long, X, 2022) |
| "Chronic pain is prevalent, and approximately half of patients with chronic pain experience sleep disturbance." | 2.94 | Phase II double-blind randomised controlled trial of exogenous administration of melatonin in chronic pain (DREAM-CP): a study protocol. ( Adam, R; Columb, M; Galley, H; Kanakarajan, S; Onyeakazi, U, 2020) |
| "Chronic orofacial pain can greatly improve following treatment of the underlying insomnia, and therefore, re-evaluation of COFP is advised after 1 month of treatment." | 2.55 | An update of management of insomnia in patients with chronic orofacial pain. ( Almoznino, G; Benoliel, R; Haviv, Y; Sharav, Y, 2017) |
| "Melatonin (MLT) has been implicated in several pathophysiological states, including pain." | 1.72 | Acute and Chronic Pain Preclinical Models to Study the Analgesic Properties of Melatonergic Compounds. ( Comai, S; De Gregorio, D, 2022) |
| "In this study, chronic pain was induced by spared nerve injury model (SNI) for 4 weeks." | 1.48 | Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis. ( Li, C; Liu, M; Ma, H; Mu, N; Shi, Z; Wang, Y; Yang, J; Yang, Z; Yin, Y; Yu, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| De Gregorio, D | 1 |
| Comai, S | 1 |
| Adam, R | 1 |
| Kanakarajan, S | 1 |
| Onyeakazi, U | 1 |
| Columb, M | 1 |
| Galley, H | 1 |
| Liu, W | 1 |
| Jiang, H | 1 |
| Liu, X | 1 |
| Hu, S | 1 |
| Li, H | 1 |
| Feng, Y | 1 |
| Ke, J | 1 |
| Long, X | 1 |
| Yang, Z | 1 |
| Li, C | 1 |
| Wang, Y | 1 |
| Yang, J | 1 |
| Yin, Y | 1 |
| Liu, M | 1 |
| Shi, Z | 1 |
| Mu, N | 1 |
| Yu, L | 1 |
| Ma, H | 1 |
| Haack, M | 1 |
| Simpson, N | 1 |
| Sethna, N | 1 |
| Kaur, S | 1 |
| Mullington, J | 1 |
| Learman, LA | 1 |
| Almoznino, G | 1 |
| Haviv, Y | 1 |
| Sharav, Y | 1 |
| Benoliel, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| SurgerySMART: Studying Melatonin and Recovery in Teens[NCT06093477] | 40 participants (Anticipated) | Interventional | 2024-07-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for melatonin and Pain, Chronic
| Article | Year |
|---|---|
Sleep deficiency and chronic pain: potential underlying mechanisms and clinical implications.
Topics: Analgesics, Opioid; Animals; Chronic Pain; Humans; Hypothalamo-Hypophyseal System; Melatonin; Pain M | 2020 |
What is new in chronic pelvic pain?: best articles from the past year.
Topics: Antioxidants; Chronic Pain; Endometriosis; Female; Humans; Melatonin; Musculoskeletal Diseases; Pelv | 2014 |
An update of management of insomnia in patients with chronic orofacial pain.
Topics: Amines; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Chronic Pain; Cognitive Behavioral | 2017 |
1 trial available for melatonin and Pain, Chronic
| Article | Year |
|---|---|
Phase II double-blind randomised controlled trial of exogenous administration of melatonin in chronic pain (DREAM-CP): a study protocol.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Central Nervous System Depressants | 2020 |
3 other studies available for melatonin and Pain, Chronic
| Article | Year |
|---|---|
Acute and Chronic Pain Preclinical Models to Study the Analgesic Properties of Melatonergic Compounds.
Topics: Acetamides; Analgesics; Animals; Chronic Pain; Melatonin; Neuralgia | 2022 |
Melatonin Abates TMJOA Chronic Pain by MT
Topics: Animals; Chronic Pain; Humans; Melatonin; Neurons; Osteoarthritis; Rats; Rats, Sprague-Dawley; Temef | 2022 |
Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chronic Pain; Immunohistochemistry; Mal | 2018 |