Page last updated: 2024-10-19

melatonin and Osteoporosis, Postmenopausal

melatonin has been researched along with Osteoporosis, Postmenopausal in 6 studies

Osteoporosis, Postmenopausal: Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.

Research Excerpts

ExcerptRelevanceReference
"Treatment with melatonin is safe in postmenopausal women with osteopenia."2.80The effect of melatonin treatment on postural stability, muscle strength, and quality of life and sleep in postmenopausal women: a randomized controlled trial. ( Amstrup, AK; Mosekilde, L; Rejnmark, L; Sikjaer, T, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharan, K1
Lewis, K1
Furukawa, T1
Yadav, VK1
Xu, L1
Zhang, L1
Wang, Z1
Li, C1
Li, S1
Li, L1
Fan, Q1
Zheng, L1
Amstrup, AK1
Sikjaer, T1
Mosekilde, L1
Rejnmark, L1
Ostrowska, Z2
Kos-Kudla, B2
Marek, B2
Swietochowska, E2
Górski, J2
Kajdaniuk, D1
Sandyk, R1
Anastasiadis, PG1
Anninos, PA1
Tsagas, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Osteopenia With Melatonin: Effects on BMD, Muscle Strength and Quality of Life[NCT01690000]81 participants (Actual)Interventional2012-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Changes in Bone Mineral Density (BMD)

Effects of melatonin on BMD will be assessed through DXA-scans (NCT01690000)
Timeframe: baseline and end of study (after 12 months)

Interventionpercentage of change in BMD (Mean)
Melatonin1+3-0.05
Placebo-1.45

Reviews

1 review available for melatonin and Osteoporosis, Postmenopausal

ArticleYear
Is postmenopausal osteoporosis related to pineal gland functions?
    The International journal of neuroscience, 1992, Volume: 62, Issue:3-4

    Topics: Aged; Bone Diseases, Metabolic; Calcium; Estrogens; Female; Humans; Magnetics; Melatonin; Methoxsale

1992

Trials

1 trial available for melatonin and Osteoporosis, Postmenopausal

ArticleYear
The effect of melatonin treatment on postural stability, muscle strength, and quality of life and sleep in postmenopausal women: a randomized controlled trial.
    Nutrition journal, 2015, Sep-30, Volume: 14

    Topics: Aged; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Double-Blind Method; Female

2015

Other Studies

4 other studies available for melatonin and Osteoporosis, Postmenopausal

ArticleYear
Regulation of bone mass through pineal-derived melatonin-MT2 receptor pathway.
    Journal of pineal research, 2017, Volume: 63, Issue:2

    Topics: Animals; Bone and Bones; Calcification, Physiologic; Female; Humans; Melatonin; Mice; Mice, Knockout

2017
Melatonin Suppresses Estrogen Deficiency-Induced Osteoporosis and Promotes Osteoblastogenesis by Inactivating the NLRP3 Inflammasome.
    Calcified tissue international, 2018, Volume: 103, Issue:4

    Topics: Animals; Cell Differentiation; Female; Humans; Inflammasomes; Melatonin; Mice; Mice, Inbred C57BL; N

2018
Assessment of the relationship between circadian variations of salivary melatonin levels and type I collagen metabolism in postmenopausal obese women.
    Neuro endocrinology letters, 2001, Volume: 22, Issue:2

    Topics: Body Constitution; Body Mass Index; Bone and Bones; Circadian Rhythm; Collagen; Collagen Type I; Fem

2001
Assessment of the relationship between dynamic pattern of nighttime levels of melatonin and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis.
    Neuro endocrinology letters, 2001, Volume: 22, Issue:2

    Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Calcium; Circadian Rhythm; Collagen; Coll

2001