Page last updated: 2024-10-19

melatonin and Nocturia

melatonin has been researched along with Nocturia in 11 studies

Nocturia: Frequent URINATION at night that interrupts sleep. It is often associated with outflow obstruction, DIABETES MELLITUS, or bladder inflammation (CYSTITIS).

Research Excerpts

ExcerptRelevanceReference
" Sixty women with nocturia, aged > 55 years, were prospectively recruited and were later randomly allocated to treatment (melatonin 2 mg/day, n = 30) and control (placebo, n = 30) arms for 2 weeks."9.69Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial. ( Asumpinwong, C; Hengrasmee, P; Leerasiri, P; Pariyaeksut, P, 2023)
"This study showed that adding melatonin to the classic treatment of BPH patients with tamsulosin could significantly reduce the likelihood of nocturia by 2."9.51The effect of Melatonin on Improving the benign Prostatic Hyperplasia Urinary Symptoms, a Randomized Clinical Trial. ( Ayati, M; Fotovat, A; Momeni, SA; Nasseri, A; Nowroozi, MR; Samadzadeh, B; Sharifi, L; Yavari, S, 2022)
"From the 26 patients who completed the study, there was no significant difference observed in the signs or symptoms of nocturia when taking 2 mg melatonin compared to placebo."9.27Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS). ( Canham, L; Cotterill, N; Cottrell, D; Delgado, D; Drake, MJ; Homewood, J; Inglis, K; Johnson, L; Kisanga, MC; Owen, D; White, P, 2018)
"This study will evaluate whether melatonin reduces the frequency of nocturia episodes in MS patients, and therefore whether 'Circadin' has the potential to reduce LUTS and fatigue, and improve cognition and overall quality of life."9.24Protocol for a randomized, double blind, placebo controlled, crossover trial of Melatonin for treatment of Nocturia in adults with Multiple Sclerosis (MeNiMS). ( Canham, L; Cotterill, N; Cottrell, D; Delgado, D; Drake, MJ; Inglis, K; Owen, D; White, P, 2017)
"Univariate comparisons between the 261 and 600 study participants with and without nocturia, respectively, showed marginal to significant associations of nocturia with age, gender, body mass index, estimated glomerular filtration rate, calcium channel blockers, benign prostatic hyperplasia, total voided urine volume, urinary 6-sulfatoxymelatonin, duration in bed, day length, and daytime and nighttime physical activity."7.80Association between melatonin secretion and nocturia in elderly individuals: a cross-sectional study of the HEIJO-KYO cohort. ( Kurumatani, N; Obayashi, K; Saeki, K, 2014)
" Sixty women with nocturia, aged > 55 years, were prospectively recruited and were later randomly allocated to treatment (melatonin 2 mg/day, n = 30) and control (placebo, n = 30) arms for 2 weeks."5.69Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial. ( Asumpinwong, C; Hengrasmee, P; Leerasiri, P; Pariyaeksut, P, 2023)
"Nocturia is one of the commonest non-motor symptoms in Parkinson's disease (PD)."5.62Exploratory pilot study of exogenous sustained-release melatonin on nocturia in Parkinson's disease. ( Baldwin, J; Batla, A; Bhatia, KP; deMin, L; Eriksson, S; Islam, S; Melbourne, C; Pakzad, M; Panicker, JN; Simeoni, S; Uchiyama, T, 2021)
"This study showed that adding melatonin to the classic treatment of BPH patients with tamsulosin could significantly reduce the likelihood of nocturia by 2."5.51The effect of Melatonin on Improving the benign Prostatic Hyperplasia Urinary Symptoms, a Randomized Clinical Trial. ( Ayati, M; Fotovat, A; Momeni, SA; Nasseri, A; Nowroozi, MR; Samadzadeh, B; Sharifi, L; Yavari, S, 2022)
"From the 26 patients who completed the study, there was no significant difference observed in the signs or symptoms of nocturia when taking 2 mg melatonin compared to placebo."5.27Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS). ( Canham, L; Cotterill, N; Cottrell, D; Delgado, D; Drake, MJ; Homewood, J; Inglis, K; Johnson, L; Kisanga, MC; Owen, D; White, P, 2018)
"This study will evaluate whether melatonin reduces the frequency of nocturia episodes in MS patients, and therefore whether 'Circadin' has the potential to reduce LUTS and fatigue, and improve cognition and overall quality of life."5.24Protocol for a randomized, double blind, placebo controlled, crossover trial of Melatonin for treatment of Nocturia in adults with Multiple Sclerosis (MeNiMS). ( Canham, L; Cotterill, N; Cottrell, D; Delgado, D; Drake, MJ; Inglis, K; Owen, D; White, P, 2017)
"Univariate comparisons between the 261 and 600 study participants with and without nocturia, respectively, showed marginal to significant associations of nocturia with age, gender, body mass index, estimated glomerular filtration rate, calcium channel blockers, benign prostatic hyperplasia, total voided urine volume, urinary 6-sulfatoxymelatonin, duration in bed, day length, and daytime and nighttime physical activity."3.80Association between melatonin secretion and nocturia in elderly individuals: a cross-sectional study of the HEIJO-KYO cohort. ( Kurumatani, N; Obayashi, K; Saeki, K, 2014)
"The features specific to the elderly nocturia group are as follows: (1) a decrease of the nighttime plasma melatonin level, (2) an increase of nighttime plasma catecholamine levels, (3) an increase of daytime and nighttime plasma natriuretic peptide levels, (4) an increase of blood pressure, (5) a decrease of daytime and nighttime urinary osmotic pressure, (6) an increase of total urine volume, and (7) an increase of the edema ratio before sleeping."3.74Biochemical and body composition analysis of nocturia in the elderly. ( Miyazato, M; Nishijima, S; Oda, M; Ogawa, Y; Owan, T; Sugaya, K, 2008)
"Melatonin could be beneficial in the treatment of nocturia and other common bladder disorders."3.01Role of circadian rhythms and melatonin in bladder function in heath and diseases. ( Ramsay, S; Zagorodnyuk, V, 2023)
"Nocturia is one of the commonest non-motor symptoms in Parkinson's disease (PD)."1.62Exploratory pilot study of exogenous sustained-release melatonin on nocturia in Parkinson's disease. ( Baldwin, J; Batla, A; Bhatia, KP; deMin, L; Eriksson, S; Islam, S; Melbourne, C; Pakzad, M; Panicker, JN; Simeoni, S; Uchiyama, T, 2021)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's4 (36.36)24.3611
2020's5 (45.45)2.80

Authors

AuthorsStudies
Fotovat, A1
Samadzadeh, B1
Ayati, M1
Nowroozi, MR1
Momeni, SA1
Yavari, S1
Nasseri, A1
Sharifi, L1
Miyake, M1
Nishimura, N1
Ohnishi, S1
Oda, Y1
Miyamoto, T1
Shimizu, T1
Hori, S1
Morizawa, Y1
Gotoh, D1
Nakai, Y1
Anai, S1
Torimoto, K1
Aoki, K1
Fujii, T1
Tanaka, N1
Fujimoto, K1
Leerasiri, P1
Pariyaeksut, P1
Hengrasmee, P1
Asumpinwong, C1
Ramsay, S1
Zagorodnyuk, V1
Batla, A1
Simeoni, S1
Uchiyama, T1
deMin, L1
Baldwin, J1
Melbourne, C1
Islam, S1
Bhatia, KP1
Pakzad, M1
Eriksson, S1
Panicker, JN1
Delgado, D2
Canham, L2
Cotterill, N2
Cottrell, D2
Drake, MJ2
Inglis, K2
Owen, D2
White, P2
Homewood, J1
Johnson, L1
Kisanga, MC1
Obayashi, K1
Saeki, K1
Kurumatani, N1
Diaz, M1
Wolkove, N1
Elkholy, O1
Baltzan, M1
Palayew, M1
Sugaya, K1
Nishijima, S1
Oda, M1
Owan, T1
Miyazato, M1
Ogawa, Y1

Reviews

2 reviews available for melatonin and Nocturia

ArticleYear
Role of circadian rhythms and melatonin in bladder function in heath and diseases.
    Autonomic neuroscience : basic & clinical, 2023, Volume: 246

    Topics: Aged; Circadian Rhythm; Humans; Melatonin; Nocturia; Suprachiasmatic Nucleus; Urinary Bladder

2023
Sleep and aging: 2. Management of sleep disorders in older people.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2007, May-08, Volume: 176, Issue:10

    Topics: Adjuvants, Immunologic; Aged; Aging; Antidepressive Agents; Behavior Therapy; Benzodiazepines; Demen

2007

Trials

4 trials available for melatonin and Nocturia

ArticleYear
The effect of Melatonin on Improving the benign Prostatic Hyperplasia Urinary Symptoms, a Randomized Clinical Trial.
    Urology journal, 2022, Nov-08, Volume: 19, Issue:5

    Topics: Double-Blind Method; Humans; Male; Melatonin; Middle Aged; Nocturia; Prostatic Hyperplasia; Sulfonam

2022
Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial.
    International urogynecology journal, 2023, Volume: 34, Issue:2

    Topics: Aged; Double-Blind Method; Female; Humans; Melatonin; Nocturia; Outcome Assessment, Health Care; Qua

2023
Protocol for a randomized, double blind, placebo controlled, crossover trial of Melatonin for treatment of Nocturia in adults with Multiple Sclerosis (MeNiMS).
    BMC neurology, 2017, Mar-27, Volume: 17, Issue:1

    Topics: Adult; Central Nervous System Depressants; Clinical Protocols; Cross-Over Studies; Double-Blind Meth

2017
Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS).
    BMC neurology, 2018, Aug-06, Volume: 18, Issue:1

    Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Melatonin; Middle Aged;

2018

Other Studies

5 other studies available for melatonin and Nocturia

ArticleYear
Association between urine 6-sulfatoxy-melatonin level and intravesical Bacillus Calmette-Guerin treatment-induced sleep quality deterioration in patients with non-muscle invasive bladder cancer.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:7

    Topics: Administration, Intravesical; BCG Vaccine; Creatinine; Humans; Male; Melatonin; Neoplasm Invasivenes

2022
Exploratory pilot study of exogenous sustained-release melatonin on nocturia in Parkinson's disease.
    European journal of neurology, 2021, Volume: 28, Issue:6

    Topics: Adult; Aged; Delayed-Action Preparations; Humans; Male; Melatonin; Nocturia; Parkinson Disease; Pilo

2021
Association between melatonin secretion and nocturia in elderly individuals: a cross-sectional study of the HEIJO-KYO cohort.
    The Journal of urology, 2014, Volume: 191, Issue:6

    Topics: Aged; Biomarkers; Circadian Rhythm; Cross-Sectional Studies; Female; Humans; Incidence; Japan; Male;

2014
Editorial comment.
    The Journal of urology, 2014, Volume: 191, Issue:6

    Topics: Circadian Rhythm; Female; Humans; Male; Melatonin; Nocturia; Urinary Bladder; Urination

2014
Biochemical and body composition analysis of nocturia in the elderly.
    Neurourology and urodynamics, 2008, Volume: 27, Issue:3

    Topics: Adult; Age Factors; Aged; Biomarkers; Blood Pressure; Body Composition; Catecholamines; Circadian Rh

2008