melatonin has been researched along with Neurodevelopmental Disorders in 12 studies
Neurodevelopmental Disorders: These are a group of conditions with onset in the developmental period. The disorders typically manifest early in development, often before the child enters grade school, and are characterized by developmental deficits that produce impairments of personal, social, academic, or occupational functioning. (From DSM-5).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We will include randomised clinical trials comparing melatonin versus placebo or no intervention for sleep disorders in children with neurodevelopmental disorders." | 9.51 | Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials. ( Faltermeier, P; Gluud, C; Hermann, R; Horowitz, M; Jakobsen, JC; Juul, S; Jørgensen, CK; Moncrieff, J, 2022) |
| "Clinical evidence is required about the long-term efficacy and safety of melatonin treatment for sleep problems in children with neurodevelopmental disorders (NDDs) who underwent adequate sleep hygiene interventions." | 9.34 | Long-term melatonin treatment for the sleep problems and aberrant behaviors of children with neurodevelopmental disorders. ( Hamada, I; Hayashi, M; Ishikawa, Y; Mishima, K; Nagamitsu, S; Sugioka, H; Takahashi, H; Yamashita, Y; Yotsuya, O; Yuge, K, 2020) |
| "To determine the efficacy and safety of melatonin as therapy for sleep problems in children with neurodevelopmental disorders." | 8.98 | Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis. ( Abdelgadir, IS; Akobeng, AK; Gordon, MA, 2018) |
| "7 years) with neurodevelopmental disorders (n = 29: intellectual disability; n = 9: autism spectrum disorder; n = 7: attention-deficit/hyperactivity disorder) and sleep disturbances, treated with melatonin (mean duration: 326 days) with doses increased according to response." | 7.81 | Melatonin for sleep disturbance in children with neurodevelopmental disorders: prospective observational naturalistic study. ( Ayyash, HF; Cortese, S; Morton, R; Preece, P, 2015) |
| " We will include randomised clinical trials comparing melatonin versus placebo or no intervention for sleep disorders in children with neurodevelopmental disorders." | 5.51 | Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials. ( Faltermeier, P; Gluud, C; Hermann, R; Horowitz, M; Jakobsen, JC; Juul, S; Jørgensen, CK; Moncrieff, J, 2022) |
| "Children with neurodevelopmental disorders are at risk of sleep problems, typically difficulty getting to sleep, sleep/wake rhythm disturbances and reduced duration of sleep (insomnia)." | 5.42 | Melatonin for sleep problems in children with neurodevelopmental disorders. ( , 2015) |
| "Clinical evidence is required about the long-term efficacy and safety of melatonin treatment for sleep problems in children with neurodevelopmental disorders (NDDs) who underwent adequate sleep hygiene interventions." | 5.34 | Long-term melatonin treatment for the sleep problems and aberrant behaviors of children with neurodevelopmental disorders. ( Hamada, I; Hayashi, M; Ishikawa, Y; Mishima, K; Nagamitsu, S; Sugioka, H; Takahashi, H; Yamashita, Y; Yotsuya, O; Yuge, K, 2020) |
| "To determine the efficacy and safety of melatonin as therapy for sleep problems in children with neurodevelopmental disorders." | 4.98 | Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis. ( Abdelgadir, IS; Akobeng, AK; Gordon, MA, 2018) |
| "7 years) with neurodevelopmental disorders (n = 29: intellectual disability; n = 9: autism spectrum disorder; n = 7: attention-deficit/hyperactivity disorder) and sleep disturbances, treated with melatonin (mean duration: 326 days) with doses increased according to response." | 3.81 | Melatonin for sleep disturbance in children with neurodevelopmental disorders: prospective observational naturalistic study. ( Ayyash, HF; Cortese, S; Morton, R; Preece, P, 2015) |
| " However, there is still uncertainty concerning dosing regimens and a lack of other data." | 2.61 | Pediatric sleep disturbances and treatment with melatonin. ( Argentiero, A; D'Alonzo, R; Di Genova, L; Esposito, S; Fattorusso, A; Laino, D; Mencarelli, A; Mencaroni, E, 2019) |
| "Children with neurodevelopmental disorders are at risk of sleep problems, typically difficulty getting to sleep, sleep/wake rhythm disturbances and reduced duration of sleep (insomnia)." | 1.42 | Melatonin for sleep problems in children with neurodevelopmental disorders. ( , 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 5 (41.67) | 2.80 |
| Authors | Studies |
|---|---|
| Salanitro, M | 1 |
| Wrigley, T | 1 |
| Ghabra, H | 1 |
| de Haan, E | 1 |
| Hill, CM | 1 |
| Solmi, M | 1 |
| Cortese, S | 2 |
| Dack, R | 1 |
| Garstang, JJ | 1 |
| Jørgensen, CK | 3 |
| Hermann, R | 3 |
| Juul, S | 3 |
| Faltermeier, P | 3 |
| Horowitz, M | 3 |
| Moncrieff, J | 3 |
| Gluud, C | 3 |
| Jakobsen, JC | 3 |
| Bruni, O | 1 |
| Angriman, M | 1 |
| Melegari, MG | 1 |
| Ferri, R | 1 |
| Yuge, K | 1 |
| Nagamitsu, S | 1 |
| Ishikawa, Y | 1 |
| Hamada, I | 1 |
| Takahashi, H | 1 |
| Sugioka, H | 1 |
| Yotsuya, O | 1 |
| Mishima, K | 1 |
| Hayashi, M | 1 |
| Yamashita, Y | 1 |
| Woodford, EC | 1 |
| McLay, L | 1 |
| France, KG | 1 |
| Blampied, NM | 1 |
| Gibbs, R | 1 |
| Swan, CE | 1 |
| Eggleston, M | 1 |
| Abdelgadir, IS | 1 |
| Gordon, MA | 1 |
| Akobeng, AK | 1 |
| Smith, ACM | 1 |
| Morse, RS | 1 |
| Introne, W | 1 |
| Duncan, WC | 1 |
| Esposito, S | 1 |
| Laino, D | 1 |
| D'Alonzo, R | 1 |
| Mencarelli, A | 1 |
| Di Genova, L | 1 |
| Fattorusso, A | 1 |
| Argentiero, A | 1 |
| Mencaroni, E | 1 |
| Ayyash, HF | 1 |
| Preece, P | 1 |
| Morton, R | 1 |
| Waldron, AY | 1 |
| Spark, MJ | 1 |
| Dennis, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II/III Clinical Trial of NPC-15 - Verification of the Efficacy for Sleep Disorders of Children With Autism Spectrum Disorders -[NCT02757066] | Phase 2/Phase 3 | 196 participants (Actual) | Interventional | 2016-06-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for melatonin and Neurodevelopmental Disorders
| Article | Year |
|---|---|
Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
Topics: Adolescent; Child; Humans; Melatonin; Neurodevelopmental Disorders; Sleep; Sleep Wake Disorders | 2022 |
Pharmacotherapeutic management of sleep disorders in children with neurodevelopmental disorders.
Topics: Antidepressive Agents; Antipsychotic Agents; Child; Dietary Supplements; Humans; Hypnotics and Sedat | 2019 |
Endogenous melatonin and sleep in individuals with Rare Genetic Neurodevelopmental Disorders (RGND): A systematic review.
Topics: Humans; Melatonin; Neurodevelopmental Disorders; Sleep; Sleep Wake Disorders; Smith-Magenis Syndrome | 2021 |
Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis.
Topics: Central Nervous System Depressants; Child; Humans; Melatonin; Models, Statistical; Neurodevelopmenta | 2018 |
Pediatric sleep disturbances and treatment with melatonin.
Topics: Child; Child Behavior; Humans; Melatonin; Mental Disorders; Neurodevelopmental Disorders; Sleep Wake | 2019 |
2 trials available for melatonin and Neurodevelopmental Disorders
5 other studies available for melatonin and Neurodevelopmental Disorders
| Article | Year |
|---|---|
Use of melatonin: a single-centre audit.
Topics: Adolescent; Autism Spectrum Disorder; Child; Humans; Melatonin; Neurodevelopmental Disorders; Sleep | 2022 |
Twenty-four-hour motor activity and body temperature patterns suggest altered central circadian timekeeping in Smith-Magenis syndrome, a neurodevelopmental disorder.
Topics: Adolescent; Adult; Body Temperature; Child; Chromosomes, Human, Pair 17; Circadian Clocks; Circadian | 2019 |
Melatonin for sleep disturbance in children with neurodevelopmental disorders: prospective observational naturalistic study.
Topics: Analysis of Variance; Central Nervous System Depressants; Child; Child, Preschool; Dose-Response Rel | 2015 |
Melatonin for sleep problems in children with neurodevelopmental disorders.
Topics: Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child; Humans; Hypnotics an | 2015 |
The Use of Melatonin by Children: Parents' Perspectives.
Topics: Adolescent; Attitude to Health; Australia; Central Nervous System Depressants; Child; Child, Prescho | 2016 |