melatonin has been researched along with Necrosis in 43 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study is to investigate whether iron overload causes the apoptosis and necrosis of bone marrow mesenchymal stem cells (BMSCs) and melatonin may prevent its toxicity." | 7.85 | Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin. ( Bao, Z; Cai, B; Ding, F; Du, Z; Feng, C; Gong, R; Han, Z; Hua, B; Huang, Q; Idiiatullina, E; Li, Y; Liu, T; Ma, W; Pavlov, V; Wang, X; Yan, G; Yang, F; Yang, L; Yu, Y; Yuan, Y; Zhang, L, 2017) |
| "In this study, chronic pain was induced by spared nerve injury model (SNI) for 4 weeks." | 5.48 | Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis. ( Li, C; Liu, M; Ma, H; Mu, N; Shi, Z; Wang, Y; Yang, J; Yang, Z; Yin, Y; Yu, L, 2018) |
| "Necrosis was evident in the DXR-treated group and some slides showed necrosis involving the fascia." | 5.36 | Melatonin ameliorates doxorubicin-induced skin necrosis in rats. ( Citak, EC; Karslioglu, Y; Kesik, V; Kismet, E; Koseoglu, V; Kurt, B; Tunc, T, 2010) |
| "The melatonin-treated rats showed markedly fewer apoptotic (TUNEL positive) cells and DNA fragmentation than did the I/R rats." | 5.35 | Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver. ( Kim, SH; Lee, SM, 2008) |
| "Melatonin was intraperitoneally administered before or/and after IR injury." | 5.33 | Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas. ( Briceño, J; Collado, JA; Cruz, A; Montilla, P; Muñoz-Casares, FC; Muñoz-Castañeda, JR; Muntané, J; Ortega, R; Padillo, FJ; Pera, C; Túnez, I, 2006) |
| " Flap necrosis rates and melatonin, oxidant, and antioxidant factors were studied." | 4.31 | Time-related variations in viability of random pattern skin flaps: An experimental study in rats. ( Aydin, OE; Ceylan, E; Cicek, K; Demir, N; Pehlevan, A; Tuzcu, A, 2023) |
| " The aim of this study is to investigate whether iron overload causes the apoptosis and necrosis of bone marrow mesenchymal stem cells (BMSCs) and melatonin may prevent its toxicity." | 3.85 | Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin. ( Bao, Z; Cai, B; Ding, F; Du, Z; Feng, C; Gong, R; Han, Z; Hua, B; Huang, Q; Idiiatullina, E; Li, Y; Liu, T; Ma, W; Pavlov, V; Wang, X; Yan, G; Yang, F; Yang, L; Yu, Y; Yuan, Y; Zhang, L, 2017) |
| " Based on this background, the present study evaluated the protective efficacy of melatonin in Echis carinatus (EC) venom-induced tissue necrosis, oxidative stress, and organ toxicity." | 3.80 | Melatonin alleviates Echis carinatus venom-induced toxicities by modulating inflammatory mediators and oxidative stress. ( Girish, KS; Hemshekhar, M; Katkar, GD; Kemparaju, K; Rangappa, KS; Santhosh, MS; Sharma, DR; Sundaram, MS; Sunitha, K, 2014) |
| " We examined the effects of the antioxidant action of melatonin against necrosis-inducing DNA damage in hepatocytes of streptozotocin (STZ)-induced diabetic rats." | 3.80 | Hepatoprotective effects of melatonin against pronecrotic cellular events in streptozotocin-induced diabetic rats. ( Bogojević, D; Grigorov, I; Ivanović-Matić, S; Jovanović, S; Martinović, V; Petrović, A; Poznanović, G; Zolotarevski, L, 2014) |
| " Myocyte necrosis and fibrosis were diminished with melatonin while vasculitis was prevented." | 3.80 | Histopathological evaluation of melatonin as a protective agent in heart injury induced by radiation in a rat model. ( Erkal, HŞ; Gürses, I; Özeren, M; Serin, M; Yücel, N, 2014) |
| " Melatonin reduces the apoptosis and necrosis in liver by inhibiting the activity of NF-kappaB and decreasing the expression of TNF-alpha." | 3.74 | [Mechanism of liver injury in severe acute pancreatitis rats and role of melatonin]. ( Fang, PP; Jia, GB; Ni, Y; Sun, XC; Wu, JS; Wu, XL; Zhang, RZ, 2008) |
| "Although both melatonin and oxytetracycline were found to be effective in autologous intraperitoneal pelvic ovary transplantation, melatonin is more effective against both the ovarian necrosis and tissue MDA level in rats." | 3.72 | Effects of melatonin and oxytetracycline in autologous intraperitoneal ovary transplantation in rats. ( Ayar, A; Celik, H; Kilic, N; Sapmaz, E; Sapmaz, T; Yasar, MA, 2003) |
| " On application of alloxan, this effect is caused by beta-cell necrosis and can be prevented by administration of melatonin, while in contrast, XO/HX did not lead to long-term morphological changes in the majority of the cells." | 3.70 | Influence of melatonin on free radical-induced changes in rat pancreatic beta-cells in vitro. ( Blume, R; Brömme, HJ; Ebelt, H; Mörke, W; Peschke, D; Peschke, E, 2000) |
| "Sepsis is one of the main causes of death among critically ill patients." | 2.55 | Oxidative stress in sepsis: Pathophysiological implications justifying antioxidant co-therapy. ( Prauchner, CA, 2017) |
| "The features of apoptotic dose responses typically have been evaluated over a broad dose-response continuum to differentiate apoptotic and necrotic responses." | 2.41 | Apoptosis: biphasic dose responses. ( Calabrese, EJ, 2001) |
| "In this study, chronic pain was induced by spared nerve injury model (SNI) for 4 weeks." | 1.48 | Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis. ( Li, C; Liu, M; Ma, H; Mu, N; Shi, Z; Wang, Y; Yang, J; Yang, Z; Yin, Y; Yu, L, 2018) |
| "Our findings suggest MLT may prevent liver fibrosis by inhibiting necroptosis-associated inflammatory signaling." | 1.42 | Melatonin attenuates carbon tetrachloride-induced liver fibrosis via inhibition of necroptosis. ( Choi, HS; Kang, JW; Lee, SM, 2015) |
| "Melatonin (Mel) has a very potent antioxidant activity, depending mainly on its capacity to act as an electron donor." | 1.40 | The effect of melatonin on a dorsal skin flap model. ( Akdemır, O; Ates, U; Bılkay, U; Demırel Sezer, E; Kerem, H; Songur, E; Sozmen, E; Turgut, M; Uyanıkgıl, Y, 2014) |
| "Melatonin has a dose dependent protective effect on the structural alterations of proximal tubules of the kidney induced by gentamicin." | 1.40 | A histological study of the effect of exogenous melatonin on gentamicin induced structural alterations of proximal tubules in rats. ( Ćosović, E; Kapić, D; Mornjaković, Z; Šahinović, M, 2014) |
| "Melatonin was proposed for use in periodontitis and peri-implantitis therapy due to its bone-supportive effects." | 1.40 | Melatonin as a candidate therapeutic drug for protecting bone cells from chlorhexidine-induced damage. ( Abouassi, T; Hellwig, E; Proksch, S; Ratka-Krüger, P; Strobel, SL; Tomakidi, P; Vach, K, 2014) |
| "Necrosis was evident in the DXR-treated group and some slides showed necrosis involving the fascia." | 1.36 | Melatonin ameliorates doxorubicin-induced skin necrosis in rats. ( Citak, EC; Karslioglu, Y; Kesik, V; Kismet, E; Koseoglu, V; Kurt, B; Tunc, T, 2010) |
| "Melatonin treatment significantly improves the functional recovery of Langerdoff hearts on reperfusion, reduces the infarct size, and decreases necrotic damage as shown by the reduced release of lactate dehydrogenase." | 1.35 | Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. ( Colantuono, G; Di Venosa, N; Fiore, T; Moro, N; Paradies, G; Petrosillo, G; Ruggiero, FM; Tiravanti, E, 2009) |
| "The melatonin-treated rats showed markedly fewer apoptotic (TUNEL positive) cells and DNA fragmentation than did the I/R rats." | 1.35 | Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver. ( Kim, SH; Lee, SM, 2008) |
| "Melatonin was found to be superior to octreotide with respect to the prevention of congestion, edema, axonal degeneration and necrosis." | 1.35 | Comparison of the effects of octreotide and melatonin in preventing nerve injury in rats with experimental spinal cord injury. ( Erol, FS; Ilhan, N; Kaplan, M; Ozercan, I; Tiftikci, M; Topsakal, C; Yakar, H, 2008) |
| "Melatonin was intraperitoneally administered before or/and after IR injury." | 1.33 | Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas. ( Briceño, J; Collado, JA; Cruz, A; Montilla, P; Muñoz-Casares, FC; Muñoz-Castañeda, JR; Muntané, J; Ortega, R; Padillo, FJ; Pera, C; Túnez, I, 2006) |
| "Melatonin has marked antioxidant properties." | 1.33 | Therapeutic value of melatonin in an experimental model of liver injury and regeneration. ( Andreadou, I; Kostopanagiotou, G; Markantonis-Kyroudis, S; Papalabros, E; Sigala, F; Sigalas, K; Theocharis, S; Triantafyllou, A, 2006) |
| " Thus, melatonin and atenolol appear to have some adverse effects in CO intoxication on the myocardial cells." | 1.33 | Effect of melatonin and atenolol on carbon monoxide cardiotoxicity: an experimental study in rats. ( Celbiş, O; Mizrak, B; Olmez, E; Parlakpinar, H, 2006) |
| "Melatonin treatment, 30 minutes preceding 2-NP, reduced the increase in LI (44." | 1.31 | Inhibition of 2-nitropropane-induced cellular proliferation, DNA synthesis and histopathological changes by melatonin. ( El-Sokkary, GH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.33) | 18.2507 |
| 2000's | 22 (51.16) | 29.6817 |
| 2010's | 18 (41.86) | 24.3611 |
| 2020's | 2 (4.65) | 2.80 |
| Authors | Studies |
|---|---|
| Aras, S | 1 |
| Tanzer, IHO | 1 |
| Karaçavuş, S | 1 |
| Sayir, N | 1 |
| Erdem, E | 1 |
| Hacımustafaoğlu, F | 1 |
| Erdoğan, CE | 1 |
| Sapmaz, T | 2 |
| İkizceli, T | 1 |
| Pençe, HH | 1 |
| Baydili, KN | 1 |
| Katmer, T | 1 |
| Aydin, OE | 1 |
| Cicek, K | 1 |
| Ceylan, E | 1 |
| Tuzcu, A | 1 |
| Pehlevan, A | 1 |
| Demir, N | 1 |
| Yang, F | 1 |
| Li, Y | 1 |
| Yan, G | 1 |
| Liu, T | 1 |
| Feng, C | 1 |
| Gong, R | 1 |
| Yuan, Y | 1 |
| Ding, F | 1 |
| Zhang, L | 1 |
| Idiiatullina, E | 1 |
| Pavlov, V | 1 |
| Han, Z | 1 |
| Ma, W | 1 |
| Huang, Q | 1 |
| Yu, Y | 1 |
| Bao, Z | 1 |
| Wang, X | 1 |
| Hua, B | 1 |
| Du, Z | 2 |
| Cai, B | 1 |
| Yang, L | 1 |
| Esrefoglu, M | 1 |
| Cetin, A | 1 |
| Taslidere, E | 1 |
| Elbe, H | 1 |
| Ates, B | 1 |
| Tok, OE | 1 |
| Aydin, MS | 1 |
| Yang, Z | 1 |
| Li, C | 1 |
| Wang, Y | 1 |
| Yang, J | 1 |
| Yin, Y | 1 |
| Liu, M | 1 |
| Shi, Z | 1 |
| Mu, N | 1 |
| Yu, L | 1 |
| Ma, H | 1 |
| Kerem, H | 1 |
| Akdemır, O | 1 |
| Ates, U | 1 |
| Uyanıkgıl, Y | 1 |
| Demırel Sezer, E | 1 |
| Bılkay, U | 1 |
| Turgut, M | 1 |
| Sozmen, E | 1 |
| Songur, E | 1 |
| Kontek, R | 1 |
| Jakubczak, M | 1 |
| Matlawska-Wasowska, K | 1 |
| Katkar, GD | 1 |
| Sundaram, MS | 1 |
| Hemshekhar, M | 1 |
| Sharma, DR | 1 |
| Santhosh, MS | 1 |
| Sunitha, K | 1 |
| Rangappa, KS | 1 |
| Girish, KS | 1 |
| Kemparaju, K | 1 |
| Kapić, D | 1 |
| Mornjaković, Z | 1 |
| Ćosović, E | 1 |
| Šahinović, M | 1 |
| Grigorov, I | 1 |
| Bogojević, D | 1 |
| Jovanović, S | 1 |
| Petrović, A | 1 |
| Ivanović-Matić, S | 1 |
| Zolotarevski, L | 1 |
| Poznanović, G | 1 |
| Martinović, V | 1 |
| Proksch, S | 1 |
| Strobel, SL | 1 |
| Vach, K | 1 |
| Abouassi, T | 1 |
| Tomakidi, P | 1 |
| Ratka-Krüger, P | 1 |
| Hellwig, E | 1 |
| Gürses, I | 1 |
| Özeren, M | 1 |
| Serin, M | 1 |
| Yücel, N | 1 |
| Erkal, HŞ | 1 |
| Wang, F | 1 |
| Zhou, H | 1 |
| Chen, X | 1 |
| Zhu, F | 1 |
| Wang, Z | 1 |
| Zhang, Y | 1 |
| Lin, L | 1 |
| Qian, M | 1 |
| Zhang, X | 1 |
| Li, X | 1 |
| Hao, A | 1 |
| Choi, HS | 1 |
| Kang, JW | 1 |
| Lee, SM | 2 |
| Prauchner, CA | 1 |
| Ni, Y | 1 |
| Wu, JS | 1 |
| Fang, PP | 1 |
| Wu, XL | 1 |
| Sun, XC | 1 |
| Jia, GB | 1 |
| Zhang, RZ | 1 |
| Petrosillo, G | 1 |
| Colantuono, G | 1 |
| Moro, N | 1 |
| Ruggiero, FM | 1 |
| Tiravanti, E | 1 |
| Di Venosa, N | 1 |
| Fiore, T | 1 |
| Paradies, G | 1 |
| Kesik, V | 1 |
| Kurt, B | 1 |
| Tunc, T | 1 |
| Karslioglu, Y | 1 |
| Citak, EC | 1 |
| Kismet, E | 1 |
| Koseoglu, V | 1 |
| Langer, SW | 1 |
| Patschan, D | 1 |
| Hildebrandt, A | 1 |
| Rinneburger, J | 1 |
| Wessels, JT | 1 |
| Patschan, S | 1 |
| Becker, JU | 1 |
| Henze, E | 1 |
| Krüger, A | 1 |
| Müller, GA | 1 |
| Malekinejad, H | 1 |
| Rezabakhsh, A | 1 |
| Rahmani, F | 1 |
| Hobbenaghi, R | 1 |
| Xu, C | 1 |
| Wu, A | 1 |
| Zhu, H | 1 |
| Fang, H | 1 |
| Xu, L | 1 |
| Ye, J | 1 |
| Shen, J | 1 |
| Czeczuga-Semeniuk, E | 1 |
| Wołczyński, S | 1 |
| Anchim, T | 1 |
| Dziecioł, J | 1 |
| Dabrowska, M | 1 |
| Pietruczuk, M | 1 |
| El-Sokkary, GH | 1 |
| Dziegiel, P | 1 |
| Surowiak, P | 1 |
| Rabczyński, J | 1 |
| Zabel, M | 1 |
| Kunduzova, OR | 1 |
| Escourrou, G | 1 |
| Seguelas, MH | 1 |
| Delagrange, P | 1 |
| De La Farge, F | 1 |
| Cambon, C | 1 |
| Parini, A | 1 |
| Sapmaz, E | 1 |
| Ayar, A | 1 |
| Celik, H | 1 |
| Kilic, N | 1 |
| Yasar, MA | 1 |
| Gurlek, A | 1 |
| Aydogan, H | 1 |
| Parlakpinar, H | 3 |
| Bay-Karabulut, A | 1 |
| Celik, M | 1 |
| Sezgin, N | 1 |
| Acet, A | 2 |
| Rodríguez-Reynoso, S | 1 |
| Leal, C | 1 |
| Portilla-de Buen, E | 1 |
| Castillo, JC | 1 |
| Ramos-Solano, F | 1 |
| Kavakli, A | 1 |
| Sahna, E | 1 |
| Yahsi, S | 1 |
| Ogeturk, M | 1 |
| Maharaj, DS | 1 |
| Maharaj, H | 1 |
| Daya, S | 1 |
| Glass, BD | 1 |
| Muñoz-Casares, FC | 1 |
| Padillo, FJ | 1 |
| Briceño, J | 1 |
| Collado, JA | 1 |
| Muñoz-Castañeda, JR | 1 |
| Ortega, R | 1 |
| Cruz, A | 1 |
| Túnez, I | 1 |
| Montilla, P | 1 |
| Pera, C | 1 |
| Muntané, J | 1 |
| Sigala, F | 1 |
| Theocharis, S | 1 |
| Sigalas, K | 1 |
| Markantonis-Kyroudis, S | 1 |
| Papalabros, E | 1 |
| Triantafyllou, A | 1 |
| Kostopanagiotou, G | 1 |
| Andreadou, I | 1 |
| Mizrak, B | 1 |
| Celbiş, O | 1 |
| Olmez, E | 1 |
| Noyan, T | 1 |
| Kömüroğlu, U | 1 |
| Bayram, I | 1 |
| Sekeroğlu, MR | 1 |
| Ozturk, F | 1 |
| Ozturk, IC | 1 |
| Batcioglu, K | 1 |
| Vardi, N | 1 |
| Kim, SH | 1 |
| Erol, FS | 1 |
| Kaplan, M | 1 |
| Tiftikci, M | 1 |
| Yakar, H | 1 |
| Ozercan, I | 1 |
| Ilhan, N | 1 |
| Topsakal, C | 1 |
| Woodgate, A | 1 |
| MacGibbon, G | 1 |
| Walton, M | 1 |
| Dragunow, M | 1 |
| Ebelt, H | 1 |
| Peschke, D | 1 |
| Brömme, HJ | 1 |
| Mörke, W | 1 |
| Blume, R | 1 |
| Peschke, E | 1 |
| Harms, C | 1 |
| Lautenschlager, M | 1 |
| Bergk, A | 1 |
| Freyer, D | 1 |
| Weih, M | 1 |
| Dirnagl, U | 1 |
| Weber, JR | 1 |
| Hörtnagl, H | 1 |
| Kölsch, H | 1 |
| Ludwig, M | 1 |
| Lütjohann, D | 1 |
| Rao, ML | 1 |
| Calabrese, EJ | 1 |
2 reviews available for melatonin and Necrosis
| Article | Year |
|---|---|
Oxidative stress in sepsis: Pathophysiological implications justifying antioxidant co-therapy.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Humans; Melatonin; Mitochondria; Multiple | 2017 |
Apoptosis: biphasic dose responses.
Topics: Animals; Antioxidants; Apoptosis; Cycloheximide; Dementia; Dimethylformamide; Dose-Response Relation | 2001 |
41 other studies available for melatonin and Necrosis
| Article | Year |
|---|---|
Effect of melatonin on low and high dose radiotherapy induced thyroid injury.
Topics: Animals; Female; Melatonin; Necrosis; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; | 2023 |
Time-related variations in viability of random pattern skin flaps: An experimental study in rats.
Topics: Animals; Antioxidants; Circadian Rhythm; Melatonin; Necrosis; Postoperative Complications; Rats; Ski | 2023 |
Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin.
Topics: Animals; Apoptosis; Bone Marrow Cells; Caspase 3; Cell Survival; Disease Models, Animal; Ferric Comp | 2017 |
Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Female; Hemorrhage; Inflammation; Liver; Liver Cirrhosi | 2017 |
Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chronic Pain; Immunohistochemistry; Mal | 2018 |
The effect of melatonin on a dorsal skin flap model.
Topics: Animals; Antioxidants; Catalase; Epithelium; Female; Malondialdehyde; Melatonin; Models, Animal; Nec | 2014 |
The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Camptothecin; Cell Line, | 2014 |
Melatonin alleviates Echis carinatus venom-induced toxicities by modulating inflammatory mediators and oxidative stress.
Topics: Animals; Free Radicals; Hemorrhage; Inflammation Mediators; Kidney; Liver; Melatonin; Mice; Muscle, | 2014 |
A histological study of the effect of exogenous melatonin on gentamicin induced structural alterations of proximal tubules in rats.
Topics: Animals; Antioxidants; Cytoplasm; Dose-Response Relationship, Drug; Gentamicins; Injections, Intrape | 2014 |
Hepatoprotective effects of melatonin against pronecrotic cellular events in streptozotocin-induced diabetic rats.
Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Male; Melatonin; Necrosis; Oxidative St | 2014 |
Melatonin as a candidate therapeutic drug for protecting bone cells from chlorhexidine-induced damage.
Topics: 3T3 Cells; Animals; Anti-Infective Agents, Local; Antioxidants; Apoptosis; Cell Count; Cell Death; C | 2014 |
Histopathological evaluation of melatonin as a protective agent in heart injury induced by radiation in a rat model.
Topics: Animals; Cardiomyopathies; Coronary Artery Disease; Coronary Vessels; Cytoprotection; Fibrosis; Male | 2014 |
Cytoprotective effect of melatonin against hypoxia/serum deprivation-induced cell death of bone marrow mesenchymal stem cells in vitro.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Hypoxia; Cell Survival; Cellular Mic | 2015 |
Melatonin attenuates carbon tetrachloride-induced liver fibrosis via inhibition of necroptosis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Hepatocytes; HMGB1 Protein; Interleukin-1alpha; Interleuki | 2015 |
[Mechanism of liver injury in severe acute pancreatitis rats and role of melatonin].
Topics: Animals; Apoptosis; Liver; Male; Melatonin; Necrosis; NF-kappa B; Pancreatitis, Acute Necrotizing; R | 2008 |
Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening.
Topics: Animals; Antioxidants; Calcium; Cardiolipins; Cardiovascular Agents; Cyclosporine; Cytochromes c; He | 2009 |
Melatonin ameliorates doxorubicin-induced skin necrosis in rats.
Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Glutathione Peroxidase; Male; Malondialdehyde; Melatonin; | 2010 |
RE: Kesik et al: melatonin ameliorates doxorubicin-induced skin necrosis in rats.
Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Doxorubicin; Melatonin; Necrosis; Rats; Sensiti | 2010 |
The hormone melatonin stimulates renoprotective effects of "early outgrowth" endothelial progenitor cells in acute ischemic kidney injury.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Movement; Cells, Cultured; Endothelial C | 2012 |
Silymarin regulates the cytochrome P450 3A2 and glutathione peroxides in the liver of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cytochrome P-450 CYP3A; Diabetes Mellitus, Experimental; Drug | 2012 |
Melatonin is involved in the apoptosis and necrosis of pancreatic cancer cell line SW-1990 via modulating of Bcl-2/Bax balance.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Cell | 2013 |
Effect of melatonin and all-trans retinoic acid on the proliferation and induction of the apoptotic pathway in the culture of human breast cancer cell line MCF-7.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Count; Cell Division; Dose-Response Relatio | 2002 |
Inhibition of 2-nitropropane-induced cellular proliferation, DNA synthesis and histopathological changes by melatonin.
Topics: Animals; Anticonvulsants; Cell Division; DNA; Drug Interactions; Hepatocytes; Male; Melatonin; Mutag | 2002 |
Effect of melatonin on cytotoxic effects of daunorubicin on myocardium and on transplantable Morris hepatoma in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Daunorubicin; Heart; In Situ Nick-End | 2002 |
Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion.
Topics: Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Caspase 3; Caspases; Creatinine; Enzyme Activ | 2003 |
Effects of melatonin and oxytetracycline in autologous intraperitoneal ovary transplantation in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Female; Graft Survival; Malondialdehyde; Melatonin; Ne | 2003 |
Protective effect of melatonin on random pattern skin flap necrosis in pinealectomized rat.
Topics: Animals; Dose-Response Relationship, Drug; Female; Glutathione; Glutathione Peroxidase; Malondialdeh | 2004 |
Melatonin ameliorates renal ischemia/reperfusion injury.
Topics: Animals; Creatinine; Glutathione; Kidney; Lipid Peroxidation; Male; Melatonin; Necrosis; Nitric Oxid | 2004 |
The effects of melatonin on focal cerebral ischemia-reperfusion model.
Topics: Animals; Brain Ischemia; Cell Survival; Cerebral Cortex; Disease Models, Animal; Infarction, Middle | 2004 |
Melatonin and 6-hydroxymelatonin protect against iron-induced neurotoxicity.
Topics: Animals; Antioxidants; Hippocampus; Iron; Lipid Peroxidation; Male; Melatonin; Necrosis; Neurotoxici | 2006 |
Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas.
Topics: Amylases; Animals; Apoptosis; Caspase 3; Caspases; Catalase; DNA Fragmentation; Glutathione; Glutath | 2006 |
Therapeutic value of melatonin in an experimental model of liver injury and regeneration.
Topics: Alanine Transaminase; Aldehydes; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisonin | 2006 |
Effect of melatonin and atenolol on carbon monoxide cardiotoxicity: an experimental study in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Carbon Monoxide Poisoning; Carboxyhemoglobin; Female | 2006 |
Comparison of the effects of melatonin and pentoxifylline on carbon tetrachloride-induced liver toxicity in mice.
Topics: Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver In | 2006 |
The effect of melatonin on 7,12-dimethyl-benz[a]anthracene injury in comparison with vitamin E + selenium in mouse kidneys.
Topics: Animals; Antioxidants; Benz(a)Anthracenes; Catalase; Female; Glutathione Peroxidase; Kidney; Kidney | 2006 |
Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver.
Topics: Animals; Apoptosis; Liver; Male; Melatonin; Necrosis; Oxidation-Reduction; Rats; Reperfusion Injury | 2008 |
Comparison of the effects of octreotide and melatonin in preventing nerve injury in rats with experimental spinal cord injury.
Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration | 2008 |
The toxicity of 6-hydroxydopamine on PC12 and P19 cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aurintricarboxylic Acid; Biological Transport; Bisbenzimi | 1999 |
Influence of melatonin on free radical-induced changes in rat pancreatic beta-cells in vitro.
Topics: Alloxan; Animals; Electron Spin Resonance Spectroscopy; Female; Free Radical Scavengers; Free Radica | 2000 |
Melatonin is protective in necrotic but not in caspase-dependent, free radical-independent apoptotic neuronal cell death in primary neuronal cultures.
Topics: Animals; Antioxidants; Apoptosis; Aziridines; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cu | 2000 |
Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta.
Topics: Antioxidants; Ascorbic Acid; Brain; Caspase 3; Caspases; Estradiol; Free Radicals; Humans; Hydroxych | 2001 |