melatonin has been researched along with Nasal Polyps in 3 studies
Nasal Polyps: Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-six patients undergoing ESS for chronic sinusitis and polyp removal were enrolled and randomly assigned to receive either oral clonidine or melatonin as preoperative premedication." | 5.19 | Improved quality of surgical field during endoscopic sinus surgery after clonidine premedication--a pilot study. ( Burduk, PK; Cywinski, JB; Kazmierczak, W; Kusza, K; Wawrzyniak, K, 2014) |
| "Melatonin protects HNEpCs from damage in inflammation and reduces IL-33 and TSLP expression of HNEpCs." | 4.31 | Melatonin reduces IL-33 and TSLP expression in human nasal epithelial cells by scavenging ROS directly. ( Gong, MJ; Hu, ZZ; Lou, M; Ma, RP; Wang, YS; Zhang, HB; Zhang, Y; Zheng, GX, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, MJ | 1 |
| Zhang, HB | 1 |
| Lou, M | 1 |
| Wang, YS | 1 |
| Ma, RP | 1 |
| Hu, ZZ | 1 |
| Zheng, GX | 1 |
| Zhang, Y | 1 |
| Senturk, E | 1 |
| Yildirim, YS | 1 |
| Ozturan, O | 1 |
| Tekkeli, SEK | 1 |
| Kiziltaş, MV | 1 |
| Wawrzyniak, K | 1 |
| Burduk, PK | 1 |
| Cywinski, JB | 1 |
| Kusza, K | 1 |
| Kazmierczak, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Pre-operative Oral Steroids on Blood Loss in Endoscopic Sinus Surgery for Chronic Rhinosinusitis Without Polyps[NCT05095961] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2023-03-31 | Withdrawn (stopped due to Technical difficulties encountered with recording intraoperative blood loss; unable to proceed with study.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for melatonin and Nasal Polyps
| Article | Year |
|---|---|
Improved quality of surgical field during endoscopic sinus surgery after clonidine premedication--a pilot study.
Topics: Adult; Arterial Pressure; Chronic Disease; Clonidine; Endoscopy; Female; Heart Rate; Hemodynamics; H | 2014 |
2 other studies available for melatonin and Nasal Polyps
| Article | Year |
|---|---|
Melatonin reduces IL-33 and TSLP expression in human nasal epithelial cells by scavenging ROS directly.
Topics: Cytokines; Epithelial Cells; Humans; Inflammation; Interleukin-33; Melatonin; Nasal Polyps; Reactive | 2023 |
Melatonin deficiency at tissue level: a possible aetiological factor in nasal polyposis.
Topics: Adult; Endoscopy; Female; Humans; Male; Melatonin; Nasal Polyps; Nose Deformities, Acquired; Paranas | 2019 |