Page last updated: 2024-10-19

melatonin and Myopia

melatonin has been researched along with Myopia in 15 studies

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
"Reduced levels of retinal dopamine, a key regulator of eye development, are associated with experimental myopia in various species, but are not seen in the myopic eyes of C57BL/6 mice, which are deficient in melatonin, a neurohormone having extensive interactions with dopamine."8.12Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia. ( Chen, WH; Cui, LJ; Gong, X; Huang, F; Li, YY; Liu, AL; Liu, YF; Ma, YY; Qian, KW; Qu, J; Wang, Q; Weng, SJ; Wu, XH; Yang, XL; Yang, Z; Yu, CX; Zhong, YM; Zhou, X, 2022)
"For reserpine (which was most extensively studied) electroretinograms were recorded to test retinal function [Fig."5.29Studies on the role of the retinal dopamine/melatonin system in experimental refractive errors in chickens. ( Bartmann, M; Hagel, G; Schaeffel, F; Zrenner, E, 1995)
"Reduced levels of retinal dopamine, a key regulator of eye development, are associated with experimental myopia in various species, but are not seen in the myopic eyes of C57BL/6 mice, which are deficient in melatonin, a neurohormone having extensive interactions with dopamine."4.12Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia. ( Chen, WH; Cui, LJ; Gong, X; Huang, F; Li, YY; Liu, AL; Liu, YF; Ma, YY; Qian, KW; Qu, J; Wang, Q; Weng, SJ; Wu, XH; Yang, XL; Yang, Z; Yu, CX; Zhong, YM; Zhou, X, 2022)
"We aimed to study the effect and mechanism of retinal melanopsin on lens-induced myopia in guinea pigs, as well as the interactions between melanopsin and other myopic regulation neurotransmitters such as dopamine and melatonin, and to explore the possible role of melanopsin in the prevention of myopia development."3.96Regulation of Retinal Melanopsin on Lens-induced Myopia in Guinea Pigs. ( Chen, Y; Guan, X; Mao, J; Zhang, X; Zheng, W; Zhou, X, 2020)
"Experimental animal models of myopia demonstrate that higher melatonin (Mel) and lower dopamine (DA) concentrations actively promote axial elongation."3.85Myopes have significantly higher serum melatonin concentrations than non-myopes. ( Cobice, D; Kearney, S; O'Donoghue, L; Pourshahidi, LK; Saunders, KJ, 2017)
"To investigate (i) the effect of monochromatic light on inhibiting induction of light-induced melatonin and (ii) the roles of melanopsin and MT1 receptor in light-induced myopia in the guinea pig."3.77Effects of 530 nm green light on refractive status, melatonin, MT1 receptor, and melanopsin in the guinea pig. ( Chu, R; Lu, Y; Wang, F; Zhou, J, 2011)
"For reserpine (which was most extensively studied) electroretinograms were recorded to test retinal function [Fig."1.29Studies on the role of the retinal dopamine/melatonin system in experimental refractive errors in chickens. ( Bartmann, M; Hagel, G; Schaeffel, F; Zrenner, E, 1995)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's2 (13.33)29.6817
2010's5 (33.33)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Nickla, DL1
Rucker, F1
Taylor, CP1
Sarfare, S1
Chen, W1
Elin-Calcador, J1
Wang, X1
Qian, KW1
Li, YY1
Wu, XH1
Gong, X1
Liu, AL1
Chen, WH1
Yang, Z1
Cui, LJ1
Liu, YF1
Ma, YY1
Yu, CX1
Huang, F1
Wang, Q1
Zhou, X2
Qu, J1
Zhong, YM1
Yang, XL1
Weng, SJ1
Zhang, C2
Zhu, Z2
Zhao, J2
Li, Y2
Zhang, Z2
Zheng, Y2
Zheng, W1
Chen, Y2
Zhang, X1
Guan, X1
Mao, J1
Chakraborty, R1
Micic, G1
Thorley, L1
Nissen, TR1
Lovato, N1
Collins, MJ1
Lack, LC1
Martínez-Águila, A1
Martín-Gil, A1
Carpena-Torres, C1
Pastrana, C1
Carracedo, G1
Kearney, S1
O'Donoghue, L1
Pourshahidi, LK1
Cobice, D1
Saunders, KJ1
Abbott, KS1
Queener, HM1
Ostrin, LA2
Burfield, HJ1
Carkeet, A1
Nebbioso, M1
Plateroti, AM1
Pucci, B1
Pescosolido, N1
Wang, F1
Zhou, J1
Lu, Y1
Chu, R1
Rada, JA1
Wiechmann, AF1
Schaeffel, F2
Bartmann, M1
Hagel, G1
Zrenner, E1
Hoffmann, M1
Appen, RE1
Mares-Perlman, J1

Reviews

2 reviews available for melatonin and Myopia

ArticleYear
Ubiquitous light-emitting diodes: Potential threats to retinal circadian rhythms and refractive development.
    The Science of the total environment, 2023, Mar-01, Volume: 862

    Topics: Circadian Clocks; Circadian Rhythm; Humans; Melatonin; Myopia; Refraction, Ocular; Retina

2023
Ubiquitous light-emitting diodes: Potential threats to retinal circadian rhythms and refractive development.
    The Science of the total environment, 2023, Mar-01, Volume: 862

    Topics: Circadian Clocks; Circadian Rhythm; Humans; Melatonin; Myopia; Refraction, Ocular; Retina

2023
Ubiquitous light-emitting diodes: Potential threats to retinal circadian rhythms and refractive development.
    The Science of the total environment, 2023, Mar-01, Volume: 862

    Topics: Circadian Clocks; Circadian Rhythm; Humans; Melatonin; Myopia; Refraction, Ocular; Retina

2023
Ubiquitous light-emitting diodes: Potential threats to retinal circadian rhythms and refractive development.
    The Science of the total environment, 2023, Mar-01, Volume: 862

    Topics: Circadian Clocks; Circadian Rhythm; Humans; Melatonin; Myopia; Refraction, Ocular; Retina

2023
Influence of Circadian Rhythm in the Eye: Significance of Melatonin in Glaucoma.
    Biomolecules, 2021, 02-24, Volume: 11, Issue:3

    Topics: Animals; Circadian Rhythm; Dry Eye Syndromes; Glaucoma; Humans; Intraocular Pressure; Melatonin; Myo

2021

Other Studies

13 other studies available for melatonin and Myopia

ArticleYear
Effects of morning and evening exposures to blue light of varying illuminance on ocular growth rates and ocular rhythms in chicks.
    Experimental eye research, 2022, Volume: 217

    Topics: Animals; Chickens; Child; Choroid; Circadian Rhythm; Humans; Light; Melatonin; Myopia; Refraction, O

2022
Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia.
    Neuroscience bulletin, 2022, Volume: 38, Issue:9

    Topics: Animals; Disease Models, Animal; Dopamine; Melatonin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; My

2022
Regulation of Retinal Melanopsin on Lens-induced Myopia in Guinea Pigs.
    Optometry and vision science : official publication of the American Academy of Optometry, 2020, Volume: 97, Issue:7

    Topics: Animals; Axial Length, Eye; Blotting, Western; Chromatography, High Pressure Liquid; Contact Lenses;

2020
Myopia, or near-sightedness, is associated with delayed melatonin circadian timing and lower melatonin output in young adult humans.
    Sleep, 2021, 03-12, Volume: 44, Issue:3

    Topics: Actigraphy; Adult; Circadian Rhythm; Humans; Melatonin; Myopia; Sleep; Young Adult

2021
Myopes have significantly higher serum melatonin concentrations than non-myopes.
    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2017, Volume: 37, Issue:5

    Topics: Adolescent; Biomarkers; Chromatography, Liquid; Female; Follow-Up Studies; Humans; Male; Melatonin;

2017
The ipRGC-Driven Pupil Response with Light Exposure, Refractive Error, and Sleep.
    Optometry and vision science : official publication of the American Academy of Optometry, 2018, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Female; Humans; Light; Male; Melatonin; Myopia; Photic Stimulation; Pupil; Retina

2018
Ocular and Systemic Diurnal Rhythms in Emmetropic and Myopic Adults.
    Investigative ophthalmology & visual science, 2019, 05-01, Volume: 60, Issue:6

    Topics: Adult; Analysis of Variance; Axial Length, Eye; Blood Pressure; Body Temperature; Circadian Rhythm;

2019
Role of the dopaminergic system in the development of myopia in children and adolescents.
    Journal of child neurology, 2014, Volume: 29, Issue:12

    Topics: Adolescent; Child; Dopamine; Female; Humans; Male; Melatonin; Myopia; Phenethylamines; Receptors, Do

2014
Effects of 530 nm green light on refractive status, melatonin, MT1 receptor, and melanopsin in the guinea pig.
    Current eye research, 2011, Volume: 36, Issue:2

    Topics: Animals; Biometry; Blotting, Western; Chromatography, High Pressure Liquid; Fluorescent Antibody Tec

2011
Melatonin receptors in chick ocular tissues: implications for a role of melatonin in ocular growth regulation.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:1

    Topics: Animals; Blotting, Western; Chickens; Choroid; Circadian Rhythm; Cornea; Eye; Fluorescent Antibody T

2006
Studies on the role of the retinal dopamine/melatonin system in experimental refractive errors in chickens.
    Vision research, 1995, Volume: 35, Issue:9

    Topics: 5,7-Dihydroxytryptamine; Animals; Chickens; Circadian Rhythm; Dopamine; Electroretinography; Male; M

1995
Melatonin and deprivation myopia in chickens.
    Neurochemistry international, 1996, Volume: 28, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Chickens; Circadian Rhythm; Electroretinography;

1996
Are the sky and night lights falling?
    Archives of ophthalmology (Chicago, Ill. : 1960), 2000, Volume: 118, Issue:5

    Topics: Animals; Eye; Humans; Infant; Infant Care; Infant, Newborn; Lighting; Melatonin; Myopia; Pineal Glan

2000