melatonin has been researched along with Muscular Dystrophy, Duchenne in 3 studies
Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin treatment increased total glutathione content and lowered the oxidized/reduced glutathione ratio, indicating a better redox status of the muscle." | 1.37 | Melatonin improves muscle function of the dystrophic mdx5Cv mouse, a model for Duchenne muscular dystrophy. ( Dorchies, OM; Hibaoui, Y; Patthey-Vuadens, O; Reutenauer-Patte, J; Ruegg, UT, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chahbouni, M | 2 |
| Escames, G | 2 |
| Venegas, C | 1 |
| Sevilla, B | 2 |
| García, JA | 1 |
| López, LC | 2 |
| Muñoz-Hoyos, A | 2 |
| Molina-Carballo, A | 2 |
| Acuña-Castroviejo, D | 2 |
| Hibaoui, Y | 1 |
| Reutenauer-Patte, J | 1 |
| Patthey-Vuadens, O | 1 |
| Ruegg, UT | 1 |
| Dorchies, OM | 1 |
| Doerrier, C | 1 |
1 trial available for melatonin and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Melatonin treatment counteracts the hyperoxidative status in erythrocytes of patients suffering from Duchenne muscular dystrophy.
Topics: Child; Child, Preschool; Enzyme Stability; Erythrocytes; Glutathione Disulfide; Glutathione Peroxida | 2011 |
2 other studies available for melatonin and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Melatonin treatment normalizes plasma pro-inflammatory cytokines and nitrosative/oxidative stress in patients suffering from Duchenne muscular dystrophy.
Topics: Adolescent; Analysis of Variance; Case-Control Studies; Child; Cytokines; Female; Humans; Lipid Pero | 2010 |
Melatonin improves muscle function of the dystrophic mdx5Cv mouse, a model for Duchenne muscular dystrophy.
Topics: Animals; Antioxidants; Creatinine; Disease Models, Animal; Glutathione; Humans; Isometric Contractio | 2011 |