melatonin has been researched along with Muscle Relaxation in 20 studies
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since there is evidence that the endothelial dysfunction associated with aging may be partly related to the local formation of reactive oxygen species, the purpose of this study was to examine the effect of the natural antioxidant melatonin (10(-5)mol/l) on in vitro contractility of aged aortic rings under conditions of increased oxidative stress (40 m mol/l glucose concentration in medium)." | 7.74 | Effect of melatonin on vascular responses in aortic rings of aging rats. ( Cardinali, DP; Linares, LM; Obaya-Naredo, D; Pinto, JE; Planells, FM; Reyes-Toso, CF; Ricci, CR, 2007) |
| "Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 5.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
| " Since there is evidence that the endothelial dysfunction associated with aging may be partly related to the local formation of reactive oxygen species, the purpose of this study was to examine the effect of the natural antioxidant melatonin (10(-5)mol/l) on in vitro contractility of aged aortic rings under conditions of increased oxidative stress (40 m mol/l glucose concentration in medium)." | 3.74 | Effect of melatonin on vascular responses in aortic rings of aging rats. ( Cardinali, DP; Linares, LM; Obaya-Naredo, D; Pinto, JE; Planells, FM; Reyes-Toso, CF; Ricci, CR, 2007) |
| "Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 1.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
| "Melatonin treatment increased total glutathione content and lowered the oxidized/reduced glutathione ratio, indicating a better redox status of the muscle." | 1.37 | Melatonin improves muscle function of the dystrophic mdx5Cv mouse, a model for Duchenne muscular dystrophy. ( Dorchies, OM; Hibaoui, Y; Patthey-Vuadens, O; Reutenauer-Patte, J; Ruegg, UT, 2011) |
| "Melatonin is a key neuroendocrine transducer in the circadian organization of vertebrates." | 1.37 | Melatonin effects on gut motility are independent of the relaxation mediated by the nitrergic system in the goldfish. ( Alonso-Gómez, AL; Azpeleta, C; De Pedro, N; Delgado, MJ; Isorna, E; Velarde, E, 2011) |
| "In melatonin and quercetin-treated aortas the luminal area values were significantly higher than cisplatin-treated group." | 1.36 | Vasoprotection by melatonin and quercetin in rats treated with cisplatin. ( Atalik, KE; Dündar, MA; Esen, HH; Keleş, B; Oz, M; Uyar, Y, 2010) |
| "Melatonin was also effective in restoring the impaired SNP-induced vasorelaxation seen in endothelium-denuded or L-NAME-treated aortic rings from hyperglycemic rats." | 1.33 | Melatonin restores endothelium-dependent relaxation in aortic rings of pancreatectomized rats. ( Cardinali, DP; Linares, LM; Obaya-Naredo, D; Pinto, JE; Reyes-Toso, CF; Ricci, CR; Rodríguez, RR, 2005) |
| "Melatonin treatment reversed these effects also." | 1.32 | Melatonin reverses urinary system and aorta damage in the rat due to chronic nicotine administration. ( Alican, I; Arbak, S; Ayanoglu-Dülger, G; Ersoy, Y; Kapucu, C; Paskaloglu, K; Sener, G, 2004) |
| " Dose-response curves for acetylcholine-induced, endothelium-related relaxation of aortic rings (after previous exposure to phenylephrine) and for phenylephrine-induced vasoconstriction were conducted." | 1.32 | Effect of melatonin on vascular reactivity in pancreatectomized rats. ( Arán, M; Cardinali, DP; Linares, LM; Pinto, JE; Reyes-Toso, CF; Ricci, CR; Rodríguez, RR, 2004) |
| "Treatment with melatonin (EC(50) 4." | 1.32 | Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum. ( Ayanğolu-Dülger, G; Paskaloglu, K; Sener, G, 2004) |
| " Dose-response curves for acetylcholine-induced, endothelium-related relaxation of aortic rings (after previous exposure to phenylephrine) and for serotonin-induced vasoconstriction were conducted in the presence or absence of 10-5 mol/L melatonin." | 1.31 | Vascular reactivity in diabetic rats: effect of melatonin. ( Albornoz, LE; Cardinali, DP; Damiano, PF; Linares, LM; Reyes-Toso, CF; Rosón, MI, 2002) |
| "1." | 1.30 | The vascular reactivity of melatonin. ( Monroe, KK; Watts, SW, 1998) |
| "Pretreatment with melatonin (10(-3) M) or M&B 22." | 1.28 | The mode of vasorelaxing action of melatonin in rabbit aorta. ( Oe, H; Satake, N; Sawada, T; Shibata, S, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atalik, KE | 1 |
| Keleş, B | 1 |
| Uyar, Y | 1 |
| Dündar, MA | 1 |
| Oz, M | 1 |
| Esen, HH | 1 |
| Hibaoui, Y | 1 |
| Reutenauer-Patte, J | 1 |
| Patthey-Vuadens, O | 1 |
| Ruegg, UT | 1 |
| Dorchies, OM | 1 |
| Velarde, E | 1 |
| Alonso-Gómez, AL | 1 |
| Azpeleta, C | 1 |
| Isorna, E | 1 |
| De Pedro, N | 1 |
| Delgado, MJ | 1 |
| Karasu-Minareci, E | 1 |
| Kaya, Y | 1 |
| Belgin Yildirim, F | 1 |
| Reyes-Toso, CF | 4 |
| Rosón, MI | 1 |
| Albornoz, LE | 1 |
| Damiano, PF | 1 |
| Linares, LM | 4 |
| Cardinali, DP | 4 |
| Storr, M | 1 |
| Koppitz, P | 1 |
| Sibaev, A | 1 |
| Saur, D | 1 |
| Kurjak, M | 1 |
| Franck, H | 1 |
| Schusdziarra, V | 1 |
| Allescher, HD | 1 |
| Sener, G | 2 |
| Kapucu, C | 1 |
| Paskaloglu, K | 2 |
| Ayanoglu-Dülger, G | 1 |
| Arbak, S | 1 |
| Ersoy, Y | 1 |
| Alican, I | 1 |
| Ricci, CR | 3 |
| Arán, M | 1 |
| Pinto, JE | 3 |
| Rodríguez, RR | 2 |
| Kumcu, EK | 1 |
| Büyüknacar, HS | 1 |
| Kiroğlu, OE | 1 |
| Göçmen, C | 1 |
| Döndaş, N | 1 |
| Dikmen, A | 1 |
| Ayanğolu-Dülger, G | 1 |
| Obaya-Naredo, D | 2 |
| Planells, FM | 1 |
| Weekley, LB | 3 |
| Monroe, KK | 1 |
| Watts, SW | 1 |
| Doolen, S | 1 |
| Krause, DN | 1 |
| Dubocovich, ML | 1 |
| Duckles, SP | 1 |
| Satake, N | 3 |
| Oe, H | 2 |
| Sawada, T | 1 |
| Shibata, S | 3 |
| Takagi, T | 1 |
| Usui, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identifying the Pathophysiology of Neurogenic Orthostatic Hypotension and the Effects of Melatonin on Reducing Supine Hypertension in Peripherally Intact Versus Denervated Post-ganglionic Sympathetic Nerves[NCT02963181] | Early Phase 1 | 10 participants (Actual) | Interventional | 2018-03-01 | Terminated (stopped due to PI leaving) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 other studies available for melatonin and Muscle Relaxation
| Article | Year |
|---|---|
Vasoprotection by melatonin and quercetin in rats treated with cisplatin.
Topics: Animals; Antineoplastic Agents; Antioxidants; Aorta, Thoracic; Cardiotonic Agents; Cisplatin; Female | 2010 |
Melatonin improves muscle function of the dystrophic mdx5Cv mouse, a model for Duchenne muscular dystrophy.
Topics: Animals; Antioxidants; Creatinine; Disease Models, Animal; Glutathione; Humans; Isometric Contractio | 2011 |
Melatonin effects on gut motility are independent of the relaxation mediated by the nitrergic system in the goldfish.
Topics: Acetylcholine; Animals; Arginine; Calcium; Gastrointestinal Motility; Goldfish; Melatonin; Muscle Co | 2011 |
The achilles heel in melatonin: asthma.
Topics: Acetylcholine; Animals; Asthma; Circadian Rhythm; Dose-Response Relationship, Drug; Injections, Intr | 2012 |
Vascular reactivity in diabetic rats: effect of melatonin.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes | 2002 |
Melatonin reduces non-adrenergic, non-cholinergic relaxant neurotransmission by inhibition of nitric oxide synthase activity in the gastrointestinal tract of rodents in vitro.
Topics: Adrenergic Agents; Animals; Atropine; Digestive System; Electric Stimulation; Enteric Nervous System | 2002 |
Melatonin reverses urinary system and aorta damage in the rat due to chronic nicotine administration.
Topics: Animals; Aorta; Blood Urea Nitrogen; Creatinine; Drug Administration Schedule; Drug Therapy, Combina | 2004 |
Effect of melatonin on vascular reactivity in pancreatectomized rats.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes | 2004 |
Effects of melatonin on impaired neurogenic and endothelial relaxations by bacterial lipopolysaccharide in the mouse corpus cavernosum.
Topics: Acetylcholine; Animals; Electric Stimulation; Endothelium; Escherichia coli; In Vitro Techniques; Li | 2004 |
Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental | 2004 |
Melatonin restores endothelium-dependent relaxation in aortic rings of pancreatectomized rats.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endotheli | 2005 |
Effect of melatonin on vascular responses in aortic rings of aging rats.
Topics: Acetylcholine; Aging; Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Dose-Response Relations | 2007 |
Effects of melatonin on pulmonary and coronary vessels are exerted through perivascular nerves.
Topics: Animals; Coronary Vessels; Female; In Vitro Techniques; Melatonin; Muscle Relaxation; Muscle, Smooth | 1993 |
Pharmacologic studies on the mechanism of melatonin-induced vasorelaxation in rat aorta.
Topics: Animals; Aorta, Thoracic; Atropine; Dose-Response Relationship, Drug; Lidocaine; Male; Melatonin; Mu | 1995 |
The vascular reactivity of melatonin.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Drug Interactions; Endothelium, Vascular; In Vitro Techniqu | 1998 |
Melatonin mediates two distinct responses in vascular smooth muscle.
Topics: Adrenergic alpha-Agonists; Animals; Drug Synergism; In Vitro Techniques; Male; Melatonin; Muscle Con | 1998 |
The mode of vasorelaxing action of melatonin in rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Dinoprost; In Vitro Techniques; Male; Melatonin | 1991 |
Vasorelaxing action of melatonin in rat isolated aorta; possible endothelium dependent relaxation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Mal | 1991 |
Melatonin-induced relaxation of rat aorta: interaction with adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Aorta; Dose-Resp | 1991 |
Vasorelaxing action of melatonin in rabbit basilar artery.
Topics: Animals; Basilar Artery; In Vitro Techniques; Male; Melatonin; Muscle Relaxation; Muscle, Smooth, Va | 1989 |