melatonin has been researched along with Mitochondrial Diseases in 16 studies
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin is an endogenous compound with a variety of physiological roles." | 6.55 | Melatonin as a mitochondrial protector in neurodegenerative diseases. ( Govitrapong, P; Wongprayoon, P, 2017) |
| "Melatonin is an endogenous compound with a variety of physiological roles." | 2.55 | Melatonin as a mitochondrial protector in neurodegenerative diseases. ( Govitrapong, P; Wongprayoon, P, 2017) |
| "Melatonin is a known powerful antioxidant and anti-inflammatory and increasing experimental and clinical evidence shows its beneficial effects against oxidative/nitrosative stress status, including that involving mitochondrial dysfunction." | 2.47 | Melatonin-mitochondria interplay in health and disease. ( Acuña Castroviejo, D; Escames, G; García, JA; López, A; López, LC; Reiter, RJ, 2011) |
| "Melatonin is a natural occurring compound with well-known antioxidant properties." | 2.46 | Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. ( Paradies, G; Paradies, V; Petrosillo, G; Reiter, RJ; Ruggiero, FM, 2010) |
| "Melatonin is an ancient molecule present in unicellular organisms at the very early moment of life." | 2.44 | Melatonin role in the mitochondrial function. ( Acuna-Castroviejo, D; Escames, G; Lopez, LC; Rodriguez, MI, 2007) |
| "Treatment with melatonin abrogated rotenone-induced impairment of embryo development, mitochondrial dysfunction, and ATP deficiency, and significantly decreased oxidative stress and apoptosis." | 1.56 | Melatonin enhances mitochondrial biogenesis and protects against rotenone-induced mitochondrial deficiency in early porcine embryos. ( Cui, XS; Nie, ZW; Niu, YJ; Shin, KT; Zhou, W, 2020) |
| "Melatonin treatment yielded a near complete restoration of mitochondrial function in assays of respiratory rate, membrane potential, reactive oxygen species production, and ATP levels." | 1.38 | Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells. ( Arendash, GW; Bradshaw, PC; Cao, C; Copes, N; Delic, V; Dragicevic, N; Lin, X; Mamcarz, M; Wang, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 11 (68.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, XY | 1 |
| Xiong, YM | 1 |
| Tan, YJ | 1 |
| Wang, L | 2 |
| Li, R | 1 |
| Zhang, Y | 1 |
| Liu, XM | 1 |
| Lin, XH | 1 |
| Jin, L | 1 |
| Hu, YT | 1 |
| Tang, ZH | 1 |
| Wu, ZM | 1 |
| Yin, FH | 1 |
| Wang, ZQ | 1 |
| Xiao, Y | 1 |
| Sheng, JZ | 1 |
| Huang, HF | 1 |
| Niu, YJ | 1 |
| Zhou, W | 1 |
| Nie, ZW | 1 |
| Shin, KT | 1 |
| Cui, XS | 1 |
| Wang, Z | 1 |
| Zhou, F | 1 |
| Dou, Y | 1 |
| Tian, X | 1 |
| Liu, C | 1 |
| Li, H | 1 |
| Shen, H | 1 |
| Chen, G | 1 |
| Paradies, G | 2 |
| Paradies, V | 2 |
| Ruggiero, FM | 2 |
| Petrosillo, G | 2 |
| Wongprayoon, P | 1 |
| Govitrapong, P | 1 |
| Ganie, SA | 1 |
| Dar, TA | 1 |
| Bhat, AH | 1 |
| Dar, KB | 1 |
| Anees, S | 1 |
| Zargar, MA | 1 |
| Masood, A | 1 |
| Maarman, GJ | 1 |
| Andrew, BM | 1 |
| Blackhurst, DM | 1 |
| Ojuka, EO | 1 |
| Reiter, RJ | 4 |
| Acuña Castroviejo, D | 2 |
| López, LC | 3 |
| Escames, G | 4 |
| López, A | 1 |
| García, JA | 2 |
| García-Corzo, L | 1 |
| Ortiz, F | 1 |
| Acuña-Castroviejo, D | 2 |
| Cheshchevik, VT | 1 |
| Dremza, IK | 1 |
| Lapshina, EA | 1 |
| Zabrodskaya, SV | 1 |
| Kujawa, J | 1 |
| Zavodnik, IB | 1 |
| Dragicevic, N | 1 |
| Delic, V | 1 |
| Cao, C | 1 |
| Copes, N | 1 |
| Lin, X | 1 |
| Mamcarz, M | 1 |
| Arendash, GW | 1 |
| Bradshaw, PC | 1 |
| Mayo, JC | 1 |
| Sainz, RM | 1 |
| Tan, DX | 1 |
| Antolín, I | 1 |
| Rodríguez, C | 1 |
| Martínez-Cruz, F | 1 |
| Osuna, C | 1 |
| Guerrero, JM | 1 |
| Rodriguez, MI | 1 |
| Carazo, A | 1 |
| León, J | 1 |
| Khaldy, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Melatonin Administration on the PER1 and BMAL1 Clock Genes in Patients With Parkinson's Disease[NCT04287543] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2021-05-31 | Withdrawn (stopped due to Due to the COVID-19 pandemic, we were unable to begin the study) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for melatonin and Mitochondrial Diseases
| Article | Year |
|---|---|
Mitochondrial bioenergetics decay in aging: beneficial effect of melatonin.
Topics: Aging; Animals; Antioxidants; Energy Metabolism; Humans; Melatonin; Mitochondria; Mitochondrial Dise | 2017 |
Melatonin as a mitochondrial protector in neurodegenerative diseases.
Topics: Animals; Antioxidants; Humans; Melatonin; Mitochondria; Mitochondrial Diseases; Neurodegenerative Di | 2017 |
Melatonin: A Potential Anti-Oxidant Therapeutic Agent for Mitochondrial Dysfunctions and Related Disorders.
Topics: Aging; Antioxidants; Humans; Melatonin; Metabolome; Mitochondrial Diseases; Oxidative Stress | 2016 |
Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease.
Topics: Animals; Cardiolipins; Humans; Melatonin; Mitochondria; Mitochondrial Diseases | 2010 |
Melatonin-mitochondria interplay in health and disease.
Topics: Aging; Animals; Antioxidants; Apoptosis; Biological Evolution; DNA, Mitochondrial; Energy Metabolism | 2011 |
Mitochondrial DNA and inflammatory diseases.
Topics: Autoimmune Diseases; Carrier Proteins; DNA, Mitochondrial; Humans; Immunity, Innate; Inflammation; M | 2012 |
Melatonin and Parkinson's disease.
Topics: Animals; Apoptosis; Free Radical Scavengers; Free Radicals; Humans; Inflammation; Melatonin; Mitocho | 2005 |
Melatonin role in the mitochondrial function.
Topics: Animals; Humans; Inflammation; Melatonin; Mitochondria; Mitochondrial Diseases; Neurodegenerative Di | 2007 |
Melatonin, mitochondrial homeostasis and mitochondrial-related diseases.
Topics: Animals; Antioxidants; DNA, Mitochondrial; Homeostasis; Humans; Melatonin; Mitochondria; Mitochondri | 2002 |
7 other studies available for melatonin and Mitochondrial Diseases
| Article | Year |
|---|---|
Melatonin rescues impaired penetration ability of human spermatozoa induced by mitochondrial dysfunction.
Topics: Animals; Antioxidants; Biomechanical Phenomena; Cricetinae; Female; Fertilization; Fertilization in | 2019 |
Melatonin enhances mitochondrial biogenesis and protects against rotenone-induced mitochondrial deficiency in early porcine embryos.
Topics: Animals; Embryo, Mammalian; Embryonic Development; Melatonin; Mitochondria; Mitochondrial Diseases; | 2020 |
Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.
Topics: Animals; Annexin A5; Antioxidants; Apoptosis; Benzimidazoles; Brain Edema; Brain Injuries; Carbocyan | 2018 |
Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C
Topics: Animals; Antioxidants; Cell Line; Cell Respiration; Diabetes Mellitus, Type 2; Electron Transport; M | 2017 |
Corrections by melatonin of liver mitochondrial disorders under diabetes and acute intoxication in rats.
Topics: Adenosine Diphosphate; Animals; Carbon Tetrachloride; Diabetes Mellitus, Experimental; Male; Melaton | 2011 |
Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Ca | 2012 |
Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, Vitamin E, and Vitamin C.
Topics: Aldehydes; Animals; Animals, Newborn; Ascorbic Acid; Disease Models, Animal; Drug Interactions; Fema | 2006 |