melatonin has been researched along with Memory Disorders in 65 studies
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we examined the underlying neuroprotective mechanism of melatonin against D-galactose-induced memory and synaptic dysfunction, elevated reactive oxygen species (ROS), neuroinflammation and neurodegeneration." | 7.81 | Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model. ( Ali, T; Badshah, H; Kim, MO; Kim, TH, 2015) |
| "In the present study, the effects of intraamygdalar administrations of melatonin (1 and 100μg/kg), saline and diazepam on the anxiety-like behavior and spatial memory performance in pinealectomized and sham-pinealectomized Wistar rats were investigated." | 7.77 | The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats. ( Coşkun, H; Gündüz, B; Karakaş, A; Kaya, A; Kücük, A, 2011) |
| "Since free radicals play a role in the mechanisms of brain injury after hemorrhagic stroke, the effect of melatonin (a potent antioxidant and free-radical scavenger) on outcomes was investigated after intracerebral hemorrhage (ICH) in rats." | 7.76 | Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats. ( Ayer, R; Chen, W; Hartman, R; Lekic, T; Manaenko, A; Rojas, H; Tang, J; Zhang, JH, 2010) |
| "Multiple sclerosis is a progressive autoimmune disorder of the myelin sheath and is the most common inflammatory disease of young adults." | 5.56 | Melatonin improves memory defects in a mouse model of multiple sclerosis by up-regulating cAMP-response element-binding protein and synapse-associated proteins in the prefrontal cortex. ( AboTaleb, HA; Alghamdi, BS, 2020) |
| "Melatonin has been considered as an effective remedy for circadian rhythm shift." | 5.48 | Circadian rhythm resynchronization improved isoflurane-induced cognitive dysfunction in aged mice. ( Chu, S; Cui, Y; Gu, X; Li, X; Ma, Z; Qian, Y; Shao, X; Song, J; Xia, T; Xu, F, 2018) |
| "Williams-Beuren syndrome (WBS), a neurodevelopmental disorder caused by a microdeletion on chromosomic region 7q11." | 5.43 | Correlations between behavior, memory, sleep-wake and melatonin in Williams-Beuren syndrome. ( Campos, LM; Giacheti, CM; Pinato, L; Rossi, NF; Santoro, SD, 2016) |
| " We observed that chronic administration of melatonin significantly reduced the lipid peroxidation and restored the decreased glutathione levels induced by chronic hyperhomocysteinemia." | 5.33 | Melatonin improves learning and memory performances impaired by hyperhomocysteinemia in rats. ( Baydas, G; Koz, ST; Ozer, M; Tuzcu, M; Yasar, A, 2005) |
| " In this study, we examined the underlying neuroprotective mechanism of melatonin against D-galactose-induced memory and synaptic dysfunction, elevated reactive oxygen species (ROS), neuroinflammation and neurodegeneration." | 3.81 | Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model. ( Ali, T; Badshah, H; Kim, MO; Kim, TH, 2015) |
| "In the present study, the effects of intraamygdalar administrations of melatonin (1 and 100μg/kg), saline and diazepam on the anxiety-like behavior and spatial memory performance in pinealectomized and sham-pinealectomized Wistar rats were investigated." | 3.77 | The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats. ( Coşkun, H; Gündüz, B; Karakaş, A; Kaya, A; Kücük, A, 2011) |
| "Since free radicals play a role in the mechanisms of brain injury after hemorrhagic stroke, the effect of melatonin (a potent antioxidant and free-radical scavenger) on outcomes was investigated after intracerebral hemorrhage (ICH) in rats." | 3.76 | Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats. ( Ayer, R; Chen, W; Hartman, R; Lekic, T; Manaenko, A; Rojas, H; Tang, J; Zhang, JH, 2010) |
| "Melatonin (MT) has been reported to control and prevent Alzheimer's disease (AD) in the clinic; however, the effect and mechanism of MT on AD have not been specifically described." | 2.82 | Effect and Mechanism of Exogenous Melatonin on Cognitive Deficits in Animal Models of Alzheimer's Disease: A Systematic Review and Meta-analysis. ( Qin, T; Sun, T; Xie, D; Xu, Y; Zhai, Z; Zhong, Y, 2022) |
| "Melatoninergic agonists have been shown to reliably entrain circadian rhythms, if chronobiological phase response rules are followed." | 2.53 | Melatonin and Synthetic Melatoninergic Agonists in Psychiatric and Age-associated Disorders: Successful and Unsuccessful Approaches. ( Hardeland, R, 2016) |
| "Melatonin has been found to modulate the learning and memory process in human as well as in animals." | 2.53 | The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies. ( Ahmad, AH; Othman, Z; Zakaria, R, 2016) |
| "As melatonin has been shown to enhance memory and hippocampal neurogenesis in animal models, this research investigated the neuroprotective effects of melatonin against spatial memory and hippocampal neurogenesis impairment in 5-fluorouracil (5-FU)-treated rats." | 1.56 | Melatonin attenuates 5-fluorouracil-induced spatial memory and hippocampal neurogenesis impairment in adult rats. ( Aranarochana, A; Chaisawang, P; Pannangrong, W; Sirichoat, A; Suwannakot, K; Welbat, JU; Wigmore, P, 2020) |
| "Multiple sclerosis is a progressive autoimmune disorder of the myelin sheath and is the most common inflammatory disease of young adults." | 1.56 | Melatonin improves memory defects in a mouse model of multiple sclerosis by up-regulating cAMP-response element-binding protein and synapse-associated proteins in the prefrontal cortex. ( AboTaleb, HA; Alghamdi, BS, 2020) |
| "In this study, chronic administration of memantine with melatonin improved episodic memory in the object recognition test and reduced the number of amyloid aggregates and reactive microgliosis in the brains of 5xFAD mice." | 1.51 | Effects of the drug combination memantine and melatonin on impaired memory and brain neuronal deficits in an amyloid-predominant mouse model of Alzheimer's disease. ( Beniashvili, A; Jürgenson, M; Morozova, M; Noortoots, A; Zapolski, M; Zharkovskaja, T; Zharkovsky, A, 2019) |
| " Further drug-like property analysis demonstrated that the optimized compound, 8d (WI-1758), had liver microsomal metabolic stability, was well tolerated (>2000 mg/kg), and had a rational pharmacokinetic profile, as well as an oral bioavailability of 14." | 1.48 | Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease. ( Chan, ASC; Feng, X; Hu, J; Huang, L; Li, X; Wang, Z; Yang, X, 2018) |
| " In this study, we hypothesized that chronic administration of melatonin can prevent memory impairment induced by consumption of HFD." | 1.48 | Melatonin prevents memory impairment induced by high-fat diet: Role of oxidative stress. ( Alzoubi, KH; Khabour, OF; Mahafzah, R; Mayyas, FA, 2018) |
| "Melatonin has been considered as an effective remedy for circadian rhythm shift." | 1.48 | Circadian rhythm resynchronization improved isoflurane-induced cognitive dysfunction in aged mice. ( Chu, S; Cui, Y; Gu, X; Li, X; Ma, Z; Qian, Y; Shao, X; Song, J; Xia, T; Xu, F, 2018) |
| "SPS-stimulated cognitive impairments in the object recognition task and Morris water maze were reversed by MTG treatment (25 mg/kg, i." | 1.48 | Melatonin ameliorates cognitive memory by regulation of cAMP-response element-binding protein expression and the anti-inflammatory response in a rat model of post-traumatic stress disorder. ( Hahm, DH; Lee, B; Lee, H; Shim, I, 2018) |
| "The effects of melatonin on spatial memory deficits in Alzheimer's disease (AD) have been thoroughly investigated." | 1.46 | Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway. ( Chen, W; Ding, Y; He, J; Hong, X; Peng, C; Tan, L; Wang, X; Zhang, H, 2017) |
| "Melatonin treatment could improve memory deficits, antioxidants activity and reduced MDA levels in the hippocampus." | 1.46 | Maternal administration of melatonin prevents spatial learning and memory deficits induced by developmental ethanol and lead co-exposure. ( Abrari, K; Goudarzi, I; Lashkarbolouki, T; Soleimani, E, 2017) |
| "Williams-Beuren syndrome (WBS), a neurodevelopmental disorder caused by a microdeletion on chromosomic region 7q11." | 1.43 | Correlations between behavior, memory, sleep-wake and melatonin in Williams-Beuren syndrome. ( Campos, LM; Giacheti, CM; Pinato, L; Rossi, NF; Santoro, SD, 2016) |
| "Melatonin, which promotes the metabolism of many reactive oxygen species (ROS), has antioxidant and neuroprotective properties." | 1.43 | Chronic Melatonin Treatment Prevents Memory Impairment Induced by Chronic Sleep Deprivation. ( Alhashimi, FH; Alzoubi, KH; Bani Salama, FM; Khabour, OF; Mayyas, FA; Mhaidat, NM, 2016) |
| "Melatonin is a powerful endogenousantioxidant, and the objective of this study was to explore the therapeutic role of melatonin in the treatment of 1-BP intoxication." | 1.43 | Identify Melatonin as a Novel Therapeutic Reagent in the Treatment of 1-Bromopropane(1-BP) Intoxication. ( Jiang, L; Li, M; Wang, H; Wang, S; Wang, X; Xie, K; Xu, Y; Yang, Y; Zhao, X, 2016) |
| "Treatment of melatonin, rats had shorter escape latencies and remained in the target quadrant longer compared to the HFD-fed and STZ-treated rats." | 1.43 | Melatonin attenuates the high-fat diet and streptozotocin-induced reduction in rat hippocampal neurogenesis. ( Govitrapong, P; Kamsrijai, U; Lansubsakul, N; Mukda, S; Sae-Ung, K; Wongchitrat, P, 2016) |
| "Melatonin treatment was administered 24 hours prior to Aβ1-42 administration via an intraperitoneal injection." | 1.43 | Protective effect of melatonin on soluble Aβ1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus. ( Bi, J; Hu, C; Ren, L; Wang, P; Zhang, S, 2016) |
| "Similarly, amyloid plaque loads in hippocampus and frontal cortex, as well as plasma Aβ1-42 levels, were significantly reduced by MEL in a receptor-independent manner, in contrast to MEL's efficacy in reducing cortical antioxidant gene expression (Catalase, SOD1, Glutathione Peroxidase-1, Nrf2) only when receptors were present." | 1.42 | Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice. ( Bradshaw, PC; Delic, V; O'Neal-Moffitt, G; Olcese, J, 2015) |
| "Melatonin is a multifunctional molecule and plays a crucial role in the regulation of circadian rhythms." | 1.42 | Melatonin Attenuates Memory Impairment, Amyloid-β Accumulation, and Neurodegeneration in a Rat Model of Sporadic Alzheimer's Disease. ( Kiseleva, E; Kolosova, NG; Maksimova, KY; Muraleva, NA; Rudnitskaya, EA; Stefanova, NA, 2015) |
| "The melatonin level was decreased in SI group compared with group housed (GH) group, and citalopram could partly restore the level of melatonin." | 1.42 | Citalopram attenuates tau hyperphosphorylation and spatial memory deficit induced by social isolation rearing in middle-aged rats. ( Gong, WG; Ren, QG; Wang, YJ; Zhang, ZJ; Zhou, QD, 2015) |
| "While prolonged sleep deprivation (SD) could lead to profound negative health consequences, such as impairments in vital biological functions of immunity and cognition, melatonin possesses powerful ameliorating effects against those harmful insults." | 1.42 | The potential role of melatonin on sleep deprivation-induced cognitive impairments: implication of FMRP on cognitive function. ( Choi, YY; Han, SH; Jeon, SJ; Kim, MK; Kwon, KJ; Lee, EJ; Shin, CY, 2015) |
| "Treatment with melatonin resulted in significant attenuations of oxidative damage, a decrease in the GSH/GSSG ratio, and a significant amelioration of memory impairment in this aging model." | 1.40 | Melatonin attenuates memory impairment induced by Klotho gene deficiency via interactive signaling between MT2 receptor, ERK, and Nrf2-related antioxidant potential. ( Chung, YH; Dang, DK; Jeong, JH; Kim, HC; Le, HL; Nabeshima, T; Nabeshima, Y; Nah, SY; Nam, Y; Shin, EJ; Wie, MB, 2014) |
| "Melatonin is an endogenous hormone with neuroprotective effects." | 1.39 | Melatonin attenuates isoflurane-induced acute memory impairments in aged rats. ( Chui, D; Guo, X; Li, Z; Liu, Y; Ni, C; Qian, M; Tang, Y; Tian, X; Zhou, Y, 2013) |
| "The current therapies for Alzheimer's disease (AD) are merely palliative that cannot arrest the pathologic progression of the disease." | 1.39 | Disease-modified glycogen synthase kinase-3β intervention by melatonin arrests the pathology and memory deficits in an Alzheimer's animal model. ( Hong, XP; Hu, J; Liu, D; Peng, CX; Wang, JZ; Wu, YY; Zhu, LQ, 2013) |
| "Melatonin has recently been suggested as an antioxidant that may protect neurons from oxidative stress." | 1.33 | Effects of melatonin on oxidative stress and spatial memory impairment induced by acute ethanol treatment in rats. ( Açikgöz, O; Aksu, I; Gönenç, S; Güleçer, B; Kayatekin, BM; Kiray, M; Semin, I; Sönmez, A; Topçu, A; Uysal, N, 2005) |
| " We observed that chronic administration of melatonin significantly reduced the lipid peroxidation and restored the decreased glutathione levels induced by chronic hyperhomocysteinemia." | 1.33 | Melatonin improves learning and memory performances impaired by hyperhomocysteinemia in rats. ( Baydas, G; Koz, ST; Ozer, M; Tuzcu, M; Yasar, A, 2005) |
| "Melatonin was injected intraperitoneally at the doses of 5 or 20 mg/kg of body weight immediately after induction of traumatic injury." | 1.33 | Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats. ( Acikgoz, O; Duman, M; Ozdemir, D; Ozdemir, N; Ozkan, H; Sonmez, A; Sonmez, U; Tugyan, K; Uysal, N, 2005) |
| "Melatonin improves learning and memory deficits and the behavioral responses of rats to melatonin supplementation are age dependent." | 1.33 | Comparison of the impact of melatonin on chronic ethanol-induced learning and memory impairment between young and aged rats. ( Baydas, G; Tuzcu, M; Yasar, A, 2005) |
| "Melatonin is an endogenously generated potent antioxidant." | 1.32 | Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats. ( Cheng, Y; Feng, Z; Zhang, JT, 2004) |
| "Melatonin was found to prevent significantly the decline of T-SOD, CuZn-SOD and GSH-Px activities, the increase of MDA content in the cortex and hippocampus of mouse brain induced by aluminum chloride." | 1.31 | [Effect of melatonin on learning and memory impairment induced by aluminum chloride and its mechanism]. ( Yu, CX; Zhang, Z, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.08) | 18.2507 |
| 2000's | 11 (16.92) | 29.6817 |
| 2010's | 41 (63.08) | 24.3611 |
| 2020's | 11 (16.92) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Hu, J | 2 |
| Yang, X | 2 |
| Feng, X | 1 |
| Li, X | 2 |
| Huang, L | 1 |
| Chan, ASC | 1 |
| Malek, R | 1 |
| Arribas, RL | 1 |
| Palomino-Antolin, A | 1 |
| Totoson, P | 1 |
| Demougeot, C | 1 |
| Kobrlova, T | 1 |
| Soukup, O | 1 |
| Iriepa, I | 1 |
| Moraleda, I | 1 |
| Diez-Iriepa, D | 1 |
| Godyń, J | 1 |
| Panek, D | 1 |
| Malawska, B | 1 |
| Głuch-Lutwin, M | 1 |
| Mordyl, B | 1 |
| Siwek, A | 1 |
| Chabchoub, F | 1 |
| Marco-Contelles, J | 1 |
| Kiec-Kononowicz, K | 1 |
| Egea, J | 1 |
| de Los Ríos, C | 1 |
| Ismaili, L | 1 |
| Dai, D | 1 |
| Zheng, B | 1 |
| Yu, Z | 1 |
| Lin, S | 1 |
| Tang, Y | 2 |
| Chen, M | 1 |
| Ke, P | 1 |
| Zheng, C | 1 |
| Chen, Y | 1 |
| Wu, X | 1 |
| Aranarochana, A | 4 |
| Sirichoat, A | 4 |
| Pannangrong, W | 4 |
| Wigmore, P | 4 |
| Welbat, JU | 4 |
| Haghjoo, S | 1 |
| Hedayati Ch, M | 1 |
| Rostampour, M | 1 |
| Khakpour-Taleghani, B | 1 |
| Zhai, Z | 1 |
| Xie, D | 1 |
| Qin, T | 1 |
| Zhong, Y | 1 |
| Xu, Y | 3 |
| Sun, T | 1 |
| Ivanova, N | 1 |
| Atanasova, M | 2 |
| Nenchovska, Z | 1 |
| Tchekalarova, J | 2 |
| Jürgenson, M | 1 |
| Zharkovskaja, T | 1 |
| Noortoots, A | 1 |
| Morozova, M | 1 |
| Beniashvili, A | 1 |
| Zapolski, M | 1 |
| Zharkovsky, A | 1 |
| Suwannakot, K | 2 |
| Chaisawang, P | 3 |
| Sun, C | 1 |
| Qiu, X | 1 |
| Wang, Y | 1 |
| Liu, J | 1 |
| Li, Q | 1 |
| Jiang, H | 1 |
| Li, S | 1 |
| Song, C | 1 |
| Alghamdi, BS | 2 |
| AboTaleb, HA | 1 |
| Veschsanit, N | 1 |
| Yang, JL | 1 |
| Ngampramuan, S | 1 |
| Viwatpinyo, K | 1 |
| Pinyomahakul, J | 1 |
| Lwin, T | 1 |
| Chancharoen, P | 1 |
| Rungruang, S | 1 |
| Govitrapong, P | 3 |
| Mukda, S | 2 |
| Labban, S | 1 |
| Alshehri, FS | 1 |
| Kurdi, M | 1 |
| Panmak, P | 1 |
| Nopparat, C | 1 |
| Permpoonpattana, K | 1 |
| Namyen, J | 1 |
| Shen, D | 1 |
| Tian, X | 2 |
| Sang, W | 1 |
| Song, R | 1 |
| Alzoubi, KH | 2 |
| Mayyas, FA | 2 |
| Mahafzah, R | 1 |
| Khabour, OF | 2 |
| Song, J | 1 |
| Chu, S | 1 |
| Cui, Y | 1 |
| Qian, Y | 1 |
| Xu, F | 1 |
| Shao, X | 1 |
| Ma, Z | 1 |
| Xia, T | 1 |
| Gu, X | 1 |
| Lee, B | 1 |
| Shim, I | 1 |
| Lee, H | 1 |
| Hahm, DH | 1 |
| Manousakis, JE | 1 |
| Scovelle, AJ | 1 |
| Rajaratnam, SMW | 1 |
| Naismith, SL | 1 |
| Anderson, C | 1 |
| Ilieva, K | 1 |
| Atanasova, D | 1 |
| Kortenska, L | 1 |
| Montes, S | 1 |
| Yee-Rios, Y | 1 |
| Páez-Martínez, N | 1 |
| Krutsri, S | 1 |
| Al Dera, H | 1 |
| Alassiri, M | 1 |
| Eleawa, SM | 1 |
| AlKhateeb, MA | 1 |
| Hussein, AM | 1 |
| Dallak, M | 1 |
| Sakr, HF | 1 |
| Alqahtani, S | 1 |
| Khalil, MA | 1 |
| Peng, CX | 1 |
| Liu, D | 2 |
| Hong, XP | 1 |
| Wu, YY | 2 |
| Zhu, LQ | 2 |
| Wang, JZ | 2 |
| Liu, Y | 1 |
| Ni, C | 1 |
| Zhou, Y | 1 |
| Qian, M | 1 |
| Li, Z | 1 |
| Chui, D | 1 |
| Guo, X | 1 |
| Yılmaz, T | 1 |
| Gedikli, Ö | 1 |
| Yildirim, M | 1 |
| Song, TY | 1 |
| Lin, HC | 1 |
| Chen, CL | 1 |
| Wu, JH | 1 |
| Liao, JW | 1 |
| Hu, ML | 1 |
| Hardeland, R | 1 |
| Ali, T | 2 |
| Badshah, H | 1 |
| Kim, TH | 1 |
| Kim, MO | 2 |
| Ren, QG | 1 |
| Gong, WG | 1 |
| Wang, YJ | 1 |
| Zhou, QD | 1 |
| Zhang, ZJ | 1 |
| Shin, EJ | 1 |
| Chung, YH | 1 |
| Le, HL | 1 |
| Jeong, JH | 1 |
| Dang, DK | 1 |
| Nam, Y | 1 |
| Wie, MB | 1 |
| Nah, SY | 1 |
| Nabeshima, Y | 1 |
| Nabeshima, T | 1 |
| Kim, HC | 1 |
| Kwon, KJ | 1 |
| Lee, EJ | 1 |
| Kim, MK | 1 |
| Jeon, SJ | 1 |
| Choi, YY | 1 |
| Shin, CY | 1 |
| Han, SH | 1 |
| Bani Salama, FM | 1 |
| Alhashimi, FH | 1 |
| Mhaidat, NM | 1 |
| O'Neal-Moffitt, G | 1 |
| Delic, V | 1 |
| Bradshaw, PC | 1 |
| Olcese, J | 1 |
| Rudnitskaya, EA | 1 |
| Muraleva, NA | 1 |
| Maksimova, KY | 1 |
| Kiseleva, E | 1 |
| Kolosova, NG | 1 |
| Stefanova, NA | 1 |
| Goel, R | 1 |
| Bhat, SA | 1 |
| Hanif, K | 1 |
| Nath, C | 2 |
| Shukla, R | 2 |
| Wang, S | 1 |
| Jiang, L | 1 |
| Wang, H | 1 |
| Yang, Y | 2 |
| Li, M | 1 |
| Wang, X | 4 |
| Zhao, X | 1 |
| Xie, K | 1 |
| Santoro, SD | 1 |
| Giacheti, CM | 1 |
| Rossi, NF | 1 |
| Campos, LM | 1 |
| Pinato, L | 1 |
| Wang, J | 1 |
| Cheng, X | 1 |
| Zhang, X | 1 |
| Cheng, J | 1 |
| Zeng, J | 1 |
| Zhou, W | 1 |
| Zhang, Y | 1 |
| Sharif, R | 1 |
| Aghsami, M | 1 |
| Gharghabi, M | 1 |
| Sanati, M | 1 |
| Khorshidahmad, T | 1 |
| Vakilzadeh, G | 1 |
| Mehdizadeh, H | 1 |
| Gholizadeh, S | 1 |
| Taghizadeh, G | 1 |
| Sharifzadeh, M | 1 |
| Wongchitrat, P | 1 |
| Lansubsakul, N | 1 |
| Kamsrijai, U | 1 |
| Sae-Ung, K | 1 |
| Zhang, S | 1 |
| Wang, P | 1 |
| Ren, L | 1 |
| Hu, C | 1 |
| Bi, J | 1 |
| Peng, C | 1 |
| Hong, X | 1 |
| Chen, W | 2 |
| Zhang, H | 1 |
| Tan, L | 2 |
| Ding, Y | 1 |
| He, J | 1 |
| Zakaria, R | 1 |
| Ahmad, AH | 1 |
| Othman, Z | 1 |
| Soleimani, E | 1 |
| Goudarzi, I | 1 |
| Abrari, K | 1 |
| Lashkarbolouki, T | 1 |
| Huang, LT | 1 |
| Tiao, MM | 1 |
| Tain, YL | 1 |
| Chen, CC | 1 |
| Hsieh, CS | 1 |
| Lekic, T | 1 |
| Hartman, R | 1 |
| Rojas, H | 1 |
| Manaenko, A | 1 |
| Ayer, R | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Fu, Z | 1 |
| Li, Y | 1 |
| Feng, J | 1 |
| Luo, J | 1 |
| Zhang, Q | 1 |
| Wang, Q | 1 |
| Tian, Q | 1 |
| Agrawal, R | 1 |
| Tyagi, E | 1 |
| Karakaş, A | 1 |
| Coşkun, H | 1 |
| Kaya, A | 1 |
| Kücük, A | 1 |
| Gündüz, B | 1 |
| Wang, ZH | 1 |
| Tang, H | 1 |
| Gao, XY | 1 |
| Xiong, YS | 1 |
| Tang, F | 1 |
| Nag, S | 1 |
| Shiu, SY | 1 |
| Pang, SF | 1 |
| Zhang, Z | 1 |
| Yu, CX | 1 |
| Feng, Z | 1 |
| Cheng, Y | 1 |
| Zhang, JT | 1 |
| Crowley, SJ | 1 |
| Lee, C | 1 |
| Tseng, CY | 1 |
| Fogg, LF | 1 |
| Eastman, CI | 1 |
| Gönenç, S | 1 |
| Uysal, N | 2 |
| Açikgöz, O | 2 |
| Kayatekin, BM | 1 |
| Sönmez, A | 2 |
| Kiray, M | 1 |
| Aksu, I | 1 |
| Güleçer, B | 1 |
| Topçu, A | 1 |
| Semin, I | 1 |
| Baydas, G | 3 |
| Ozer, M | 1 |
| Yasar, A | 3 |
| Tuzcu, M | 3 |
| Koz, ST | 1 |
| Ozdemir, D | 1 |
| Tugyan, K | 1 |
| Sonmez, U | 1 |
| Ozdemir, N | 1 |
| Duman, M | 1 |
| Ozkan, H | 1 |
| Ozveren, F | 1 |
| Akdemir, I | 1 |
| Shaji, AV | 1 |
| Kulkarni, SK | 1 |
| Shen, YX | 1 |
| Wei, W | 1 |
| Yang, J | 1 |
| Liu, C | 1 |
| Dong, C | 1 |
| Xu, SY | 1 |
| Sandyk, R | 1 |
| Anninos, PA | 1 |
| Tsagas, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Stellate Ganglion Block in Patients With Advanced Primary Parkinson's Disease: a Small, Open, Randomized, Controlled Clinical Study[NCT06112392] | 38 participants (Anticipated) | Interventional | 2023-07-28 | Recruiting | |||
| Piloting an Adaption of Cognitive Behavioral Therapy for Insomnia for Shift Workers (CBTI-Shift)[NCT05965609] | 60 participants (Anticipated) | Interventional | 2023-12-08 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for melatonin and Memory Disorders
| Article | Year |
|---|---|
Effect and Mechanism of Exogenous Melatonin on Cognitive Deficits in Animal Models of Alzheimer's Disease: A Systematic Review and Meta-analysis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Disease Models, Animal; Maze Learning; | 2022 |
Melatonin and Synthetic Melatoninergic Agonists in Psychiatric and Age-associated Disorders: Successful and Unsuccessful Approaches.
Topics: Acetamides; Animals; Humans; Indoles; Melatonin; Memory Disorders; Mental Disorders; Pyrans; Recepto | 2016 |
The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies.
Topics: Animals; Disease Models, Animal; Humans; Melatonin; Memory; Memory Disorders; Rodentia | 2016 |
Age-related disruption of circadian rhythms: possible relationship to memory impairment and implications for therapy with magnetic fields.
Topics: Adult; Aged; Aging; Animals; Circadian Rhythm; Humans; Magnetics; Melatonin; Memory Disorders; Middl | 1991 |
61 other studies available for melatonin and Memory Disorders
| Article | Year |
|---|---|
Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Proliferation; Drug Des | 2018 |
New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H
Topics: Alzheimer Disease; Animals; Calcium Channel Blockers; Cholinesterase Inhibitors; Humans; Memory Diso | 2019 |
Right stellate ganglion block improves learning and memory dysfunction and hippocampal injury in rats with sleep deprivation.
Topics: Animals; Autonomic Nerve Block; Hippocampus; Male; Melatonin; Memory Disorders; Neurons; Rats; Rats, | 2021 |
Melatonin Ameliorates Valproic Acid-Induced Neurogenesis Impairment: The Role of Oxidative Stress in Adult Rats.
Topics: Animals; Anticonvulsants; Antioxidants; Hippocampus; Male; Melatonin; Memory Disorders; Neurogenesis | 2021 |
Red-light radiation: does it enhance memory by increasing hippocampal LRP-1 and TRPA-1 genes expression?
Topics: Animals; Hippocampus; Lipopolysaccharides; Maze Learning; Melatonin; Memory Disorders; Rats | 2023 |
Sex-Dependent Effect of Chronic Piromelatine Treatment on Prenatal Stress-Induced Memory Deficits in Rats.
Topics: Animals; Female; Hippocampus; Indoles; Male; Maze Learning; Melatonin; Memory Disorders; Pregnancy; | 2023 |
Effects of the drug combination memantine and melatonin on impaired memory and brain neuronal deficits in an amyloid-predominant mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cholineste | 2019 |
Melatonin attenuates 5-fluorouracil-induced spatial memory and hippocampal neurogenesis impairment in adult rats.
Topics: Animals; Antimetabolites; Biomarkers; Cell Proliferation; Cognitive Dysfunction; Dentate Gyrus; Doub | 2020 |
Long-term oral melatonin alleviates memory deficits, reduces amyloid-β deposition associated with downregulation of BACE1 and mitophagy in APP/PS1 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein | 2020 |
Melatonin improves memory defects in a mouse model of multiple sclerosis by up-regulating cAMP-response element-binding protein and synapse-associated proteins in the prefrontal cortex.
Topics: Animals; Behavior, Animal; Cuprizone; Cyclic AMP Response Element-Binding Protein; Disease Models, A | 2020 |
Melatonin reverts methamphetamine-induced learning and memory impairments and hippocampal alterations in mice.
Topics: Animals; Central Nervous System Stimulants; Cognition; Hippocampus; Male; Maze Learning; Melatonin; | 2021 |
Effects of melatonin and resveratrol on recognition memory and passive avoidance performance in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Male; Mela | 2021 |
Melatonin protects against methamphetamine-induced Alzheimer's disease-like pathological changes in rat hippocampus.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Central Nervous System Stimulants; | 2021 |
Effect of Melatonin and Resveratrol against Memory Impairment and Hippocampal Damage in a Rat Model of Vascular Dementia.
Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Dementia, Vascular; Disease Models, Animal | 2016 |
Melatonin prevents memory impairment induced by high-fat diet: Role of oxidative stress.
Topics: Animals; Antioxidants; Diet, High-Fat; Hippocampus; Male; Maze Learning; Melatonin; Memory Disorders | 2018 |
Circadian rhythm resynchronization improved isoflurane-induced cognitive dysfunction in aged mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Body Temperature; Circadian Rhythm; CLOCK Proteins; Cogniti | 2018 |
Melatonin ameliorates cognitive memory by regulation of cAMP-response element-binding protein expression and the anti-inflammatory response in a rat model of post-traumatic stress disorder.
Topics: Animals; Anti-Inflammatory Agents; Cognition; Cognitive Dysfunction; Cyclic AMP Response Element-Bin | 2018 |
Advanced Circadian Timing and Sleep Fragmentation Differentially Impact on Memory Complaint Subtype in Subjective Cognitive Decline.
Topics: Aged; Chronobiology Disorders; Cognition Disorders; Female; Humans; Male; Melatonin; Memory Disorder | 2018 |
Antidepressant agomelatine attenuates behavioral deficits and concomitant pathology observed in streptozotocin-induced model of Alzheimer's disease in male rats.
Topics: Acetamides; Alzheimer Disease; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Disease Mo | 2019 |
Environmental enrichment restores oxidative balance in animals chronically exposed to toluene: Comparison with melatonin.
Topics: Animals; Antioxidants; Behavior, Animal; Cell Death; Environment; Hippocampus; Lipid Peroxidation; M | 2019 |
Melatonin protects against methotrexate-induced memory deficit and hippocampal neurogenesis impairment in a rat model.
Topics: Animals; Behavior, Animal; Cell Proliferation; Hippocampus; Male; Melatonin; Memory Disorders; Metho | 2019 |
Protective effects of melatonin against valproic acid-induced memory impairments and reductions in adult rat hippocampal neurogenesis.
Topics: Animals; Cell Proliferation; Dentate Gyrus; Hippocampus; Male; Melatonin; Memory Disorders; Neural S | 2019 |
Melatonin Improves Memory Deficits in Rats with Cerebral Hypoperfusion, Possibly, Through Decreasing the Expression of Small-Conductance Ca
Topics: Animals; Brain-Derived Neurotrophic Factor; Down-Regulation; Hippocampus; Interleukin-1beta; Male; M | 2019 |
Disease-modified glycogen synthase kinase-3β intervention by melatonin arrests the pathology and memory deficits in an Alzheimer's animal model.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Ki | 2013 |
Melatonin attenuates isoflurane-induced acute memory impairments in aged rats.
Topics: Animals; Cognition Disorders; Hippocampus; Isoflurane; Male; Maze Learning; Melatonin; Memory; Memor | 2013 |
Evaluation of spatial memory and locomotor activity during hypercortisolism induced by the administration of dexamethasone in adult male rats.
Topics: Adrenocortical Hyperfunction; Animals; Antioxidants; Ascorbic Acid; Cholinergic Antagonists; Dexamet | 2015 |
Ergothioneine and melatonin attenuate oxidative stress and protect against learning and memory deficits in C57BL/6J mice treated with D-galactose.
Topics: Alzheimer Disease; Animals; Antioxidants; Brain; Chromatography, High Pressure Liquid; Disease Model | 2014 |
Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model.
Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Brain; Disease Models, Animal; Galactose; Inflammat | 2015 |
Citalopram attenuates tau hyperphosphorylation and spatial memory deficit induced by social isolation rearing in middle-aged rats.
Topics: Animals; Brain; Citalopram; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Melat | 2015 |
Melatonin attenuates memory impairment induced by Klotho gene deficiency via interactive signaling between MT2 receptor, ERK, and Nrf2-related antioxidant potential.
Topics: Animals; Antioxidants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2014 |
Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus.
Topics: Amyloid beta-Peptides; Animals; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippoca | 2015 |
The potential role of melatonin on sleep deprivation-induced cognitive impairments: implication of FMRP on cognitive function.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antioxidants; Brain; Cell Survival; Cells, Cultured | 2015 |
Chronic Melatonin Treatment Prevents Memory Impairment Induced by Chronic Sleep Deprivation.
Topics: Animals; Biomarkers; Chronic Disease; Hippocampus; Male; Maze Learning; Melatonin; Memory; Memory Di | 2016 |
Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anxiety; Disease | 2015 |
Melatonin Attenuates Memory Impairment, Amyloid-β Accumulation, and Neurodegeneration in a Rat Model of Sporadic Alzheimer's Disease.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anim | 2015 |
Perindopril Attenuates Lipopolysaccharide-Induced Amyloidogenesis and Memory Impairment by Suppression of Oxidative Stress and RAGE Activation.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Angiotensin-Converting Enzyme In | 2016 |
Identify Melatonin as a Novel Therapeutic Reagent in the Treatment of 1-Bromopropane(1-BP) Intoxication.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Dose-Response Relationship, Drug; Glutathione; | 2016 |
Correlations between behavior, memory, sleep-wake and melatonin in Williams-Beuren syndrome.
Topics: Adolescent; Child; Child Behavior; Circadian Clocks; Cross-Sectional Studies; Female; Humans; Male; | 2016 |
The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain.
Topics: Aging; Animals; Antioxidants; Cell Proliferation; Chronic Disease; Cytokines; Drugs, Chinese Herbal; | 2016 |
Melatonin reverses H-89 induced spatial memory deficit: Involvement of oxidative stress and mitochondrial function.
Topics: Animals; Antioxidants; Cytochromes c; Disease Models, Animal; Escape Reaction; Hippocampus; Hypnotic | 2017 |
Melatonin attenuates the high-fat diet and streptozotocin-induced reduction in rat hippocampal neurogenesis.
Topics: Animals; Diet, High-Fat; Doublecortin Protein; Hippocampus; Hyperglycemia; Male; Melatonin; Memory; | 2016 |
Protective effect of melatonin on soluble Aβ1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus.
Topics: Amyloid beta-Peptides; Animals; Behavior, Animal; Disease Models, Animal; Gliosis; Hippocampus; Male | 2016 |
Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway.
Topics: Amygdala; Amyloid beta-Protein Precursor; Animals; Conditioning, Classical; Cues; Cyclic AMP Respons | 2017 |
Maternal administration of melatonin prevents spatial learning and memory deficits induced by developmental ethanol and lead co-exposure.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Catalase; Drug Administr | 2017 |
Melatonin ameliorates bile duct ligation-induced systemic oxidative stress and spatial memory deficits in developing rats.
Topics: Animals; Antioxidants; Biomarkers; Brain; Cholestasis, Extrahepatic; Common Bile Duct; Dose-Response | 2009 |
Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats.
Topics: Animals; Antioxidants; Basal Ganglia Diseases; Cerebral Hemorrhage; Corpus Striatum; Disease Models, | 2010 |
Melatonin ameliorates Alzheimer-like pathological changes and spatial memory retention impairment induced by calyculin A.
Topics: Alzheimer Disease; Animals; Antioxidants; Behavior, Animal; Disease Models, Animal; Male; Malondiald | 2011 |
Insulin receptor signaling in rat hippocampus: a study in STZ (ICV) induced memory deficit model.
Topics: Animals; Blood Glucose; Chromones; Disease Models, Animal; Donepezil; Gene Expression; Hippocampus; | 2011 |
The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats.
Topics: Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Disease Models, Ani | 2011 |
Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway.
Topics: Animals; Early Growth Response Protein 1; Guanine Nucleotide Exchange Factors; Male; Melatonin; Memo | 2013 |
The effects of melatonin and Ginkgo biloba extract on memory loss and choline acetyltransferase activities in the brain of rats infused intracerebroventricularly with beta-amyloid 1-40.
Topics: Administration, Oral; Amyloid beta-Peptides; Animals; Antioxidants; Brain; Cerebral Cortex; Choline | 2002 |
[Effect of melatonin on learning and memory impairment induced by aluminum chloride and its mechanism].
Topics: Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Animals; Antioxidants; Cerebral Cortex; Ch | 2002 |
Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats.
Topics: Alzheimer Disease; Animals; Apoptosis; Choline O-Acetyltransferase; Cognition Disorders; Disease Mod | 2004 |
Complete or partial circadian re-entrainment improves performance, alertness, and mood during night-shift work.
Topics: Adolescent; Adult; Arousal; Body Temperature; Circadian Rhythm; Cognition Disorders; Disorders of Ex | 2004 |
Effects of melatonin on oxidative stress and spatial memory impairment induced by acute ethanol treatment in rats.
Topics: Animals; Ethanol; Hippocampus; Male; Maze Learning; Melatonin; Memory Disorders; Oxidative Stress; R | 2005 |
Melatonin improves learning and memory performances impaired by hyperhomocysteinemia in rats.
Topics: Analysis of Variance; Animals; Avoidance Learning; Disease Models, Animal; Glutathione; Hippocampus; | 2005 |
Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats.
Topics: Animals; Apoptosis; Brain Injuries; Hippocampus; In Situ Nick-End Labeling; Maze Learning; Melatonin | 2005 |
Learning and memory deficits in rats induced by chronic thinner exposure are reversed by melatonin.
Topics: Adjuvants, Immunologic; Animals; Brain Chemistry; Hydrocarbons, Aromatic; Lipid Peroxidation; Male; | 2005 |
Comparison of the impact of melatonin on chronic ethanol-induced learning and memory impairment between young and aged rats.
Topics: Aging; Animals; Avoidance Learning; Brain; Escape Reaction; Ethanol; Glutathione; Learning; Lipid Pe | 2005 |
Evidence of GABAergic modulation in melatonin-induced short-term memory deficits and food consumption.
Topics: Animals; Antioxidants; Diazepam; Eating; Female; Flumazenil; GABA Modulators; Latency Period, Psycho | 1998 |
Improvement of melatonin to the learning and memory impairment induced by amyloid beta-peptide 25 - 35 in elder rats.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Avoidance Learning; Maze Learning; Melatonin; Memory; | 2001 |