melatonin has been researched along with Maple Syrup Urine Disease in 2 studies
Maple Syrup Urine Disease: An autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids (AMINO ACIDS, BRANCHED-CHAIN). These metabolites accumulate in body fluids and render a maple syrup odor. The disease is divided into classic, intermediate, intermittent, and thiamine responsive subtypes. The classic form presents in the first week of life with ketoacidosis, hypoglycemia, emesis, neonatal seizures, and hypertonia. The intermediate and intermittent forms present in childhood or later with acute episodes of ataxia and vomiting. (From Adams et al., Principles of Neurology, 6th ed, p936)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The chronic administration of BCAA pool in infant rats induced significant oxidative stress (p < 0." | 5.56 | Melatonin ameliorates oxidative stress and DNA damage of rats subjected to a chemically induced chronic model of Maple Syrup Urine Disease. ( Damiani, AP; de Andrade, VM; de Oliveira, J; Duarte, MB; Ise, K; Lemos, IC; Rezende, VL; Streck, EL; Wessler, LB, 2020) |
| "Melatonin treatment improved redox imbalance with reduced TBARS levels, increased SOD activity, and normalized CAT activity to baseline." | 1.91 | Melatonin improves behavioral parameters and oxidative stress in zebrafish submitted to a leucine-induced MSUD protocol. ( Alano, CG; da Silva Lemos, I; da Silva, GL; Dondossola, ER; Duarte, MB; Effting, PS; Medeiros, BZ; Rico, EP; Streck, EL; Torres, CA, 2023) |
| " The chronic administration of BCAA pool in infant rats induced significant oxidative stress (p < 0." | 1.56 | Melatonin ameliorates oxidative stress and DNA damage of rats subjected to a chemically induced chronic model of Maple Syrup Urine Disease. ( Damiani, AP; de Andrade, VM; de Oliveira, J; Duarte, MB; Ise, K; Lemos, IC; Rezende, VL; Streck, EL; Wessler, LB, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duarte, MB | 2 |
| Medeiros, BZ | 1 |
| da Silva Lemos, I | 1 |
| da Silva, GL | 1 |
| Alano, CG | 1 |
| Dondossola, ER | 1 |
| Torres, CA | 1 |
| Effting, PS | 1 |
| Rico, EP | 1 |
| Streck, EL | 2 |
| Wessler, LB | 1 |
| Ise, K | 1 |
| Lemos, IC | 1 |
| Rezende, VL | 1 |
| Damiani, AP | 1 |
| de Oliveira, J | 1 |
| de Andrade, VM | 1 |
2 other studies available for melatonin and Maple Syrup Urine Disease
| Article | Year |
|---|---|
Melatonin improves behavioral parameters and oxidative stress in zebrafish submitted to a leucine-induced MSUD protocol.
Topics: Amino Acids, Branched-Chain; Animals; Antioxidants; Leucine; Maple Syrup Urine Disease; Melatonin; O | 2023 |
Melatonin ameliorates oxidative stress and DNA damage of rats subjected to a chemically induced chronic model of Maple Syrup Urine Disease.
Topics: Amino Acids, Branched-Chain; Animals; Antioxidants; DNA Damage; Male; Maple Syrup Urine Disease; Mel | 2020 |