melatonin has been researched along with Malaria in 11 studies
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin promotes the development and synchronicity of parasites, thereby enhancing their spread and worsening the clinical implications." | 5.37 | Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi. ( Almeida, FM; Beraldo, FH; Bootman, M; Da Silva, AM; Garcia, CR; Gazarini, ML, 2011) |
| "Melatonin promotes the development and synchronicity of parasites, thereby enhancing their spread and worsening the clinical implications." | 1.37 | Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi. ( Almeida, FM; Beraldo, FH; Bootman, M; Da Silva, AM; Garcia, CR; Gazarini, ML, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Mallaupoma, LRC | 1 |
| Dias, BKM | 1 |
| Singh, MK | 1 |
| Honorio, RI | 1 |
| Nakabashi, M | 1 |
| Kisukuri, CM | 1 |
| Paixão, MW | 1 |
| Garcia, CRS | 1 |
| Luthra, T | 1 |
| Nayak, AK | 1 |
| Bose, S | 1 |
| Chakrabarti, S | 1 |
| Gupta, A | 1 |
| Sen, S | 1 |
| Koyama, FC | 1 |
| Azevedo, MF | 1 |
| Budu, A | 1 |
| Chakrabarti, D | 1 |
| Garcia, CR | 5 |
| Srinivasan, V | 2 |
| Spence, DW | 1 |
| Moscovitch, A | 1 |
| Pandi-Perumal, SR | 1 |
| Trakht, I | 1 |
| Brown, GM | 1 |
| Cardinali, DP | 1 |
| Gazarini, ML | 2 |
| Beraldo, FH | 3 |
| Almeida, FM | 1 |
| Bootman, M | 1 |
| Da Silva, AM | 1 |
| Schuck, DC | 1 |
| Ribeiro, RY | 1 |
| Nery, AA | 1 |
| Ulrich, H | 1 |
| Mohamed, M | 1 |
| Zakaria, R | 1 |
| Ahmad, AH | 1 |
| Hänscheid, T | 1 |
| Egan, TJ | 1 |
| Grobusch, MP | 1 |
| Mikoshiba, K | 1 |
| Guha, M | 1 |
| Maity, P | 1 |
| Choubey, V | 1 |
| Mitra, K | 1 |
| Reiter, RJ | 1 |
| Bandyopadhyay, U | 1 |
| Hotta, CT | 1 |
| Varotti, FP | 1 |
| Lopes, C | 1 |
| Markus, RP | 1 |
| Pozzan, T | 1 |
3 reviews available for melatonin and Malaria
| Article | Year |
|---|---|
Malaria: therapeutic implications of melatonin.
Topics: Animals; Antimalarials; Apoptosis; Humans; Malaria; Melatonin; Models, Biological; Plasmodium falcip | 2010 |
Malaria, anti malarial drugs and the role of melatonin.
Topics: Animals; Antimalarials; Drug Resistance; Global Health; Humans; Malaria; Malaria, Falciparum; Melato | 2012 |
Haemozoin: from melatonin pigment to drug target, diagnostic tool, and immune modulator.
Topics: Animals; Antimalarials; Crystallization; Erythrocytes; Female; Hemeproteins; Humans; Leukocytes; Mal | 2007 |
8 other studies available for melatonin and Malaria
| Article | Year |
|---|---|
Decoding the Role of Melatonin Structure on
Topics: Animals; Chloroquine; Humans; Indoles; Malaria; Malaria, Falciparum; Melatonin; Parasitemia; Parasit | 2022 |
Indole based antimalarial compounds targeting the melatonin pathway: Their design, synthesis and biological evaluation.
Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Design; Indoles; Malaria; Melatonin; Molecular | 2019 |
Melatonin-induced temporal up-regulation of gene expression related to ubiquitin/proteasome system (UPS) in the human malaria parasite Plasmodium falciparum.
Topics: Animals; Humans; Malaria; Melatonin; Parasites; Plasmodium falciparum; Proteasome Endopeptidase Comp | 2014 |
Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi.
Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Malaria; Mela | 2011 |
Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds.
Topics: Animals; Benzoxazoles; Cell Cycle; Erythrocytes; Flow Cytometry; Fluorescence; Fluorescent Dyes; Hum | 2011 |
Human malarial parasite, Plasmodium falciparum, displays capacitative calcium entry: 2-aminoethyl diphenylborinate blocks the signal transduction pathway of melatonin action on the P. falciparum cell cycle.
Topics: Animals; Boron Compounds; Calcium; Cell Cycle; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Malar | 2007 |
Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; DNA Fragmentation; Dose-Res | 2007 |
Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites.
Topics: Animals; Calcium; Circadian Rhythm; Dose-Response Relationship, Drug; Estrenes; Female; Malaria; Mel | 2000 |