Page last updated: 2024-10-19

melatonin and Malaria

melatonin has been researched along with Malaria in 11 studies

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"Melatonin promotes the development and synchronicity of parasites, thereby enhancing their spread and worsening the clinical implications."5.37Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi. ( Almeida, FM; Beraldo, FH; Bootman, M; Da Silva, AM; Garcia, CR; Gazarini, ML, 2011)
"Melatonin promotes the development and synchronicity of parasites, thereby enhancing their spread and worsening the clinical implications."1.37Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi. ( Almeida, FM; Beraldo, FH; Bootman, M; Da Silva, AM; Garcia, CR; Gazarini, ML, 2011)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Mallaupoma, LRC1
Dias, BKM1
Singh, MK1
Honorio, RI1
Nakabashi, M1
Kisukuri, CM1
Paixão, MW1
Garcia, CRS1
Luthra, T1
Nayak, AK1
Bose, S1
Chakrabarti, S1
Gupta, A1
Sen, S1
Koyama, FC1
Azevedo, MF1
Budu, A1
Chakrabarti, D1
Garcia, CR5
Srinivasan, V2
Spence, DW1
Moscovitch, A1
Pandi-Perumal, SR1
Trakht, I1
Brown, GM1
Cardinali, DP1
Gazarini, ML2
Beraldo, FH3
Almeida, FM1
Bootman, M1
Da Silva, AM1
Schuck, DC1
Ribeiro, RY1
Nery, AA1
Ulrich, H1
Mohamed, M1
Zakaria, R1
Ahmad, AH1
Hänscheid, T1
Egan, TJ1
Grobusch, MP1
Mikoshiba, K1
Guha, M1
Maity, P1
Choubey, V1
Mitra, K1
Reiter, RJ1
Bandyopadhyay, U1
Hotta, CT1
Varotti, FP1
Lopes, C1
Markus, RP1
Pozzan, T1

Reviews

3 reviews available for melatonin and Malaria

ArticleYear
Malaria: therapeutic implications of melatonin.
    Journal of pineal research, 2010, Volume: 48, Issue:1

    Topics: Animals; Antimalarials; Apoptosis; Humans; Malaria; Melatonin; Models, Biological; Plasmodium falcip

2010
Malaria, anti malarial drugs and the role of melatonin.
    Infectious disorders drug targets, 2012, Volume: 12, Issue:5

    Topics: Animals; Antimalarials; Drug Resistance; Global Health; Humans; Malaria; Malaria, Falciparum; Melato

2012
Haemozoin: from melatonin pigment to drug target, diagnostic tool, and immune modulator.
    The Lancet. Infectious diseases, 2007, Volume: 7, Issue:10

    Topics: Animals; Antimalarials; Crystallization; Erythrocytes; Female; Hemeproteins; Humans; Leukocytes; Mal

2007

Other Studies

8 other studies available for melatonin and Malaria

ArticleYear
Decoding the Role of Melatonin Structure on
    Biomolecules, 2022, 04-26, Volume: 12, Issue:5

    Topics: Animals; Chloroquine; Humans; Indoles; Malaria; Malaria, Falciparum; Melatonin; Parasitemia; Parasit

2022
Indole based antimalarial compounds targeting the melatonin pathway: Their design, synthesis and biological evaluation.
    European journal of medicinal chemistry, 2019, Apr-15, Volume: 168

    Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Design; Indoles; Malaria; Melatonin; Molecular

2019
Melatonin-induced temporal up-regulation of gene expression related to ubiquitin/proteasome system (UPS) in the human malaria parasite Plasmodium falciparum.
    International journal of molecular sciences, 2014, Dec-03, Volume: 15, Issue:12

    Topics: Animals; Humans; Malaria; Melatonin; Parasites; Plasmodium falciparum; Proteasome Endopeptidase Comp

2014
Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi.
    Journal of pineal research, 2011, Volume: 50, Issue:1

    Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Malaria; Mela

2011
Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2011, Volume: 79, Issue:11

    Topics: Animals; Benzoxazoles; Cell Cycle; Erythrocytes; Flow Cytometry; Fluorescence; Fluorescent Dyes; Hum

2011
Human malarial parasite, Plasmodium falciparum, displays capacitative calcium entry: 2-aminoethyl diphenylborinate blocks the signal transduction pathway of melatonin action on the P. falciparum cell cycle.
    Journal of pineal research, 2007, Volume: 43, Issue:4

    Topics: Animals; Boron Compounds; Calcium; Cell Cycle; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Malar

2007
Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection.
    Journal of pineal research, 2007, Volume: 43, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; DNA Fragmentation; Dose-Res

2007
Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites.
    Nature cell biology, 2000, Volume: 2, Issue:7

    Topics: Animals; Calcium; Circadian Rhythm; Dose-Response Relationship, Drug; Estrenes; Female; Malaria; Mel

2000