melatonin has been researched along with Machado-Joseph Disease in 1 studies
Machado-Joseph Disease: A dominantly-inherited ATAXIA first described in people of Azorean and Portuguese descent, and subsequently identified in Brazil, Japan, China, and Australia. This disorder is classified as one of the SPINOCEREBELLAR ATAXIAS (Type 3) and has been associated with a mutation of the MJD1 gene on chromosome 14. Clinical features include progressive ataxia, DYSARTHRIA, postural instability, nystagmus, eyelid retraction, and facial FASCICULATIONS. DYSTONIA is prominent in younger patients (referred to as Type I Machado-Joseph Disease). Type II features ataxia and ocular signs; Type III features MUSCULAR ATROPHY and a sensorimotor neuropathy; and Type IV features extrapyramidal signs combined with a sensorimotor neuropathy. (From Clin Neurosci 1995;3(1):17-22; Ann Neurol 1998 Mar;43(3):288-96)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of melatonin (MLT) therapy on insomnia and serum MLT concentration were studied in a 44-year-old man with Machado-Joseph disease." | 7.70 | [Effective melatonin therapy in a case of Machado-Joseph disease with insomnia]. ( Hamada, T; Okawa, M; Sasaki, H; Takei, A; Tashiro, K, 2000) |
| "The effects of melatonin (MLT) therapy on insomnia and serum MLT concentration were studied in a 44-year-old man with Machado-Joseph disease." | 3.70 | [Effective melatonin therapy in a case of Machado-Joseph disease with insomnia]. ( Hamada, T; Okawa, M; Sasaki, H; Takei, A; Tashiro, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takei, A | 1 |
| Okawa, M | 1 |
| Sasaki, H | 1 |
| Hamada, T | 1 |
| Tashiro, K | 1 |
1 other study available for melatonin and Machado-Joseph Disease
| Article | Year |
|---|---|
[Effective melatonin therapy in a case of Machado-Joseph disease with insomnia].
Topics: Adult; Humans; Machado-Joseph Disease; Male; Melatonin; Sleep Initiation and Maintenance Disorders; | 2000 |