melatonin has been researched along with MPTP Neurotoxicity Syndrome in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin has significant neuroprotective properties, which have been related to its ability to boost mitochondrial bioenergetics." | 1.43 | Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network. ( Acuña-Castroviejo, D; Aranda, P; Díaz-Casado, ME; Doerrier, C; Escames, G; García, JA; Guerra-Librero, A; Lima, E; López, LC; Sayed, RK, 2016) |
| "Melatonin is a natural antioxidant and free radical scavenger that has been shown to effectively reduce cellular oxidative stress and protect mitochondrial functions in vitro." | 1.37 | Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease. ( Lau, YS; Patki, G, 2011) |
| "Melatonin is a powerful antioxidant agent secreted by the pineal gland which has numerous physiological functions and seems to exert an important neuroprotective effect." | 1.35 | Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats. ( Capitelli, C; Lima, MM; Reksidler, AB; Sereniki, A; Tufik, S; Vital, MA, 2008) |
| "Treatment with melatonin completely reversed the rises in lipid peroxidation products." | 1.30 | Melatonin is protective against MPTP-induced striatal and hippocampal lesions. ( Acuña-Castroviejo, D; Coto-Montes, A; Gaia Monti, M; Ortiz, GG; Reiter, RJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Díaz-Casado, ME | 2 |
| Rusanova, I | 1 |
| Aranda, P | 2 |
| Fernández-Ortiz, M | 1 |
| Sayed, RKA | 1 |
| Fernández-Gil, BI | 1 |
| Hidalgo-Gutiérrez, A | 1 |
| Escames, G | 3 |
| López, LC | 3 |
| Acuña-Castroviejo, D | 4 |
| Naskar, A | 1 |
| Manivasagam, T | 1 |
| Chakraborty, J | 1 |
| Singh, R | 1 |
| Thomas, B | 1 |
| Dhanasekaran, M | 1 |
| Mohanakumar, KP | 1 |
| Lima, E | 1 |
| García, JA | 1 |
| Doerrier, C | 1 |
| Sayed, RK | 1 |
| Guerra-Librero, A | 1 |
| Chuang, JI | 1 |
| Pan, IL | 1 |
| Hsieh, CY | 1 |
| Huang, CY | 1 |
| Chen, PC | 1 |
| Shin, JW | 1 |
| Capitelli, C | 1 |
| Sereniki, A | 1 |
| Lima, MM | 1 |
| Reksidler, AB | 1 |
| Tufik, S | 1 |
| Vital, MA | 1 |
| Tapias, V | 1 |
| López, A | 1 |
| Camacho, E | 1 |
| Carrión, MD | 1 |
| Entrena, A | 1 |
| Gallo, MA | 1 |
| Espinosa, A | 1 |
| Patki, G | 1 |
| Lau, YS | 1 |
| Yan, MT | 1 |
| Barcia, C | 1 |
| Bautista, V | 1 |
| Sánchez-Bahillo, A | 1 |
| Fernández-Villalba, E | 1 |
| Navarro-Ruis, JM | 1 |
| Barreiro, AF | 1 |
| Poza Y Poza, M | 1 |
| Herrero, MT | 1 |
| Chen, LJ | 1 |
| Gao, YQ | 1 |
| Li, XJ | 2 |
| Shen, DH | 1 |
| Sun, FY | 2 |
| Coto-Montes, A | 1 |
| Gaia Monti, M | 1 |
| Ortiz, GG | 1 |
| Reiter, RJ | 1 |
| Itzhak, Y | 1 |
| Martin, JL | 1 |
| Black, MD | 1 |
| Ali, SF | 1 |
| Gu, J | 1 |
| Lu, SD | 1 |
13 other studies available for melatonin and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Embryo, Nonmammalian; Energy Metabolism; Mela | 2018 |
Melatonin synergizes with low doses of L-DOPA to improve dendritic spine density in the mouse striatum in experimental Parkinsonism.
Topics: Animals; Antiparkinson Agents; Central Nervous System Depressants; Corpus Striatum; Dendrites; Dopam | 2013 |
Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network.
Topics: Animals; Embryo, Nonmammalian; Melatonin; MPTP Poisoning; Nerve Tissue Proteins; Protein Serine-Thre | 2016 |
Melatonin prevents the dynamin-related protein 1-dependent mitochondrial fission and oxidative insult in the cortical neurons after 1-methyl-4-phenylpyridinium treatment.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cerebral Cortex; Dynamins; Melatonin; Mitochondrial Dynamics; | 2016 |
Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats.
Topics: Animals; Avoidance Learning; Dopamine; Immunohistochemistry; Male; Melatonin; Motor Activity; MPTP P | 2008 |
Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice.
Topics: Animals; Calcium; Corpus Striatum; Cytosol; Electron Transport Complex I; Enzyme Induction; Kynurami | 2009 |
Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease.
Topics: Adenosine Triphosphate; Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Free Radic | 2011 |
Melatonin has antioxidant effects in the brain.
Topics: Animals; Antioxidants; Brain; Dose-Response Relationship, Drug; Drinking; Melatonin; Mice; Mice, Inb | 2002 |
Circadian determinations of cortisol, prolactin and melatonin in chronic methyl-phenyl-tetrahydropyridine-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Count; Circadian Rhythm; Disease Models, | 2003 |
Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adjuvants, Immunologic; A | 2005 |
Melatonin is protective against MPTP-induced striatal and hippocampal lesions.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Hippocampus; Immunohistochem | 1997 |
Effect of melatonin on methamphetamine- and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity and methamphetamine-induced behavioral sensitization.
Topics: Animals; Body Temperature; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; | 1998 |
Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical.
Topics: Animals; Brain; Dopamine; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Melatonin; Mice; Mic | 2002 |