melatonin has been researched along with Low Bone Density in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin is a unique molecule with diverse molecular actions targeting melatonin receptors located on the plasma membrane or mitochondria or acting independently of receptors through its actions as an antioxidant or free radical scavenger to stimulate osteoblastogenesis, inhibit osteoclastogenesis, and improve bone density." | 2.72 | Melatonin effects on bone: Implications for use as a therapy for managing bone loss. ( Munmun, F; Witt-Enderby, PA, 2021) |
| "Melatonin treatment effectively blocked RANKL-induced osteoclastogenesis by inhibiting PRMT1 and asymmetric dimethylarginine (ADMA) expression." | 1.62 | Melatonin Inhibits Osteoclastogenesis and Bone Loss in Ovariectomized Mice by Regulating PRMT1-Mediated Signaling. ( Choi, JH; Jang, AR; Kim, DI; Park, JH; Park, MJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Tysoe, O | 1 |
| Li, TL | 1 |
| Liu, HD | 1 |
| Ren, MX | 1 |
| Zhou, Z | 1 |
| Jiang, WK | 1 |
| Yang, M | 1 |
| Choi, JH | 1 |
| Jang, AR | 1 |
| Park, MJ | 1 |
| Kim, DI | 1 |
| Park, JH | 1 |
| Munmun, F | 1 |
| Witt-Enderby, PA | 3 |
| Maria, S | 2 |
| Swanson, MH | 1 |
| Enderby, LT | 1 |
| D'Amico, F | 1 |
| Enderby, B | 1 |
| Samsonraj, RM | 1 |
| Dudakovic, A | 1 |
| van Wijnen, AJ | 1 |
| Sandyk, R | 1 |
| Anastasiadis, PG | 1 |
| Anninos, PA | 1 |
| Tsagas, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is Dietary Melatonin Supplementation a Viable Adjunctive Therapy for Chronic Periodontitis? A Preliminary Randomized Clinical Trial.[NCT03368430] | Phase 4 | 74 participants (Actual) | Interventional | 2016-07-04 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for melatonin and Low Bone Density
| Article | Year |
|---|---|
Melatonin effects on bone: Implications for use as a therapy for managing bone loss.
Topics: Animals; Bone and Bones; Bone Diseases, Metabolic; Circadian Rhythm; Humans; Melatonin | 2021 |
Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal disease and for use in bone-grafting procedures.
Topics: Animals; Bone Diseases, Metabolic; Bone Transplantation; Humans; Melatonin; Menopause; Mice; Osteobl | 2014 |
Is postmenopausal osteoporosis related to pineal gland functions?
Topics: Aged; Bone Diseases, Metabolic; Calcium; Estrogens; Female; Humans; Magnetics; Melatonin; Methoxsale | 1992 |
4 other studies available for melatonin and Low Bone Density
| Article | Year |
|---|---|
Melatonin prevents diabetes mellitus-induced bone loss.
Topics: Bone Diseases, Metabolic; Diabetes Mellitus; Humans; Melatonin | 2021 |
Daytime administration of melatonin has better protective effects on bone loss in ovariectomized rats.
Topics: Animals; Bone Density; Bone Diseases, Metabolic; Female; Femur; Humans; Melatonin; Osteoporosis; Ova | 2023 |
Melatonin Inhibits Osteoclastogenesis and Bone Loss in Ovariectomized Mice by Regulating PRMT1-Mediated Signaling.
Topics: Animals; Bone Diseases, Metabolic; Bone Resorption; Cell Differentiation; Cells, Cultured; Down-Regu | 2021 |
Melatonin-micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal osteopen
Topics: Aged; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Cholecalciferol; Cocu | 2017 |