melatonin has been researched along with Liver Diseases in 50 studies
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to investigate the impact of a short-term feeding with HFD on oxidative status, enteric microbiota, intestinal motility and the effects of antibiotics and/or melatonin treatments on diet-induced hepato-intestinal dysfunction and inflammation." | 7.91 | The effects of antibiotics and melatonin on hepato-intestinal inflammation and gut microbial dysbiosis induced by a short-term high-fat diet consumption in rats. ( Akdeniz, E; Aksu, B; Arabacı Tamer, S; Bagriacik, F; Cayirli, YB; Çetinel, Ş; Cilingir Kaya, ÖT; Kahraman, MM; Onur, ND; Sahin, D; Yeğen, BÇ; Yildirim, A; Yuksel, M, 2019) |
| "To investigate the protective effect of melatonin on liver after intestinal ischemia-reperfusion injury in rats." | 7.74 | Melatonin protects liver from intestine ischemia reperfusion injury in rats. ( Gu, X; Li, JY; Qin, YM; Yin, HZ; Zhang, WH; Zhou, Y, 2008) |
| " Herein, we examined the effect of melatonin on the neutrophil apoptosis in ischemia and reperfusion of the human liver." | 7.72 | Altered neutrophil apoptosis activity is reversed by melatonin in liver ischemia-reperfusion. ( Chen, HM; Chen, JC; Chiu, TF; Ng, CJ, 2003) |
| "Melatonin is a powerful endogenous antioxidant produced by the pineal gland and a variety of other organs and many studies confirm its benefits against oxidative stress including lipid peroxidation, protein mutilation and molecular degeneration in various organs, including the liver." | 6.53 | Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review. ( Alatorre-Jiménez, MA; Almeida-Souza, P; Cantín-Golet, A; Esteban-Zubero, E; García, JJ; López-Pingarrón, L; Reiter, RJ; Reyes-Gonzales, MC; Ruiz-Ruiz, FJ; Tan, DX, 2016) |
| "Melatonin has pleiotropic properties such as suppressive effects on serum level of autotaxin which relieves itching of atopic dermatitis." | 5.48 | Is melatonin effective for pruritus caused by liver disease? ( Esmaeili, A; Namazi, S, 2018) |
| "Melatonin treatment reversed all these oxidant and antioxidant parameters to control values as well as serum liver enzymes." | 5.35 | Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus. ( Fadillioglu, E; Gursul, C; Iraz, M; Kurcer, Z; Parlakpinar, H, 2008) |
| " The aim of the present study was to investigate the impact of a short-term feeding with HFD on oxidative status, enteric microbiota, intestinal motility and the effects of antibiotics and/or melatonin treatments on diet-induced hepato-intestinal dysfunction and inflammation." | 3.91 | The effects of antibiotics and melatonin on hepato-intestinal inflammation and gut microbial dysbiosis induced by a short-term high-fat diet consumption in rats. ( Akdeniz, E; Aksu, B; Arabacı Tamer, S; Bagriacik, F; Cayirli, YB; Çetinel, Ş; Cilingir Kaya, ÖT; Kahraman, MM; Onur, ND; Sahin, D; Yeğen, BÇ; Yildirim, A; Yuksel, M, 2019) |
| "To investigate the protective effect of melatonin on liver after intestinal ischemia-reperfusion injury in rats." | 3.74 | Melatonin protects liver from intestine ischemia reperfusion injury in rats. ( Gu, X; Li, JY; Qin, YM; Yin, HZ; Zhang, WH; Zhou, Y, 2008) |
| " Herein, we examined the effect of melatonin on the neutrophil apoptosis in ischemia and reperfusion of the human liver." | 3.72 | Altered neutrophil apoptosis activity is reversed by melatonin in liver ischemia-reperfusion. ( Chen, HM; Chen, JC; Chiu, TF; Ng, CJ, 2003) |
| "Melatonin was discovered in 1958 by Aaron Lerner." | 2.61 | Possible application of melatonin treatment in human diseases of the biliary tract. ( Alpini, G; Baiocchi, L; Ceci, L; Francis, H; Glaser, S; Ilaria, L; Kennedy, L; Kusumanchi, P; Liangpunsakul, S; Meng, F; Milana, M; Yang, Z; Zhou, T, 2019) |
| "Melatonin is a neurohormone associated with sleep and wakefulness and is mainly produced by the pineal gland." | 2.61 | The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health. ( Aly, H; Bhattacharya, P; Chiocca, EA; Cui, Y; Fu, J; Jiang, J; Johnson, MD; Lawler, SE; Liu, Y; Luo, C; Ma, H; Reiter, RJ; Rozental, R; Wang, X; Yang, H; Yang, Q; Yao, J; Zhang, X; Zhou, S, 2019) |
| "Melatonin is a well-known natural antioxidant, and has many bioactivities." | 2.55 | Effects of Melatonin on Liver Injuries and Diseases. ( Li, HB; Li, S; Li, Y; Meng, X; Xu, DP; Zhang, JJ; Zhou, Y, 2017) |
| "Melatonin is a powerful endogenous antioxidant produced by the pineal gland and a variety of other organs and many studies confirm its benefits against oxidative stress including lipid peroxidation, protein mutilation and molecular degeneration in various organs, including the liver." | 2.53 | Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review. ( Alatorre-Jiménez, MA; Almeida-Souza, P; Cantín-Golet, A; Esteban-Zubero, E; García, JJ; López-Pingarrón, L; Reiter, RJ; Reyes-Gonzales, MC; Ruiz-Ruiz, FJ; Tan, DX, 2016) |
| "Melatonin has pleiotropic properties such as suppressive effects on serum level of autotaxin which relieves itching of atopic dermatitis." | 1.48 | Is melatonin effective for pruritus caused by liver disease? ( Esmaeili, A; Namazi, S, 2018) |
| "Melatonin treatment led to malondialdehyde decrease after 40 days (p< 0." | 1.42 | The effect of melatonin on the liver of rats exposed to microwave radiation. ( Basic, J; Despotovic, M; Djordjevic, B; Jevtovic-Stoimenov, T; Kocic, G; Sokolovic, D; Sokolovic, DM; Veljkovic, A, 2015) |
| "Melatonin-treated BDL rats received daily melatonin 100 mg/kg/day via intraperitoneal injection." | 1.40 | Melatonin attenuates oxidative stress, liver damage and hepatocyte apoptosis after bile-duct ligation in rats. ( Aktas, C; Erboga, M; Kanter, M; Mete, R; Oran, M, 2014) |
| "Melatonin pretreatment prior to liver I/R can effectively reduce the pulmonary microvascular permeability and attenuate lipid peroxidation in the lungs." | 1.38 | Protective effect of melatonin on liver ischemia-reperfusion induced pulmonary microvascular injury in rats. ( Chen, CF; Chen, KH; Chiu, MH; Su, CL; Wang, D; Wang, JJ, 2012) |
| "Melatonin pretreatment also protected the liver against I/R injury (P < ." | 1.38 | Liver reperfusion-induced decrease in dynamic compliance and increase in airway resistance are ameliorated by preischemic treatment with melatonin through scavenging hydroxyl radicals in rat lungs. ( Chen, CF; Su, CL; Wang, D; Wang, JJ; Yeh, JH, 2012) |
| "Melatonin pretreatment effectively scavenged oxidants and hydroxyl radicals, protecting cardiac function against liver I/R-induced injury." | 1.38 | Preischemic treatment with melatonin attenuates liver reperfusion-induced impairment of cardiac function. ( Chen, KH; Chen, TH; Wang, JJ, 2012) |
| "Melatonin is a potent scavenger of reactive oxygen species and a strong antioxidant." | 1.37 | Melatonin prevents hepatic injury-induced decrease in Akt downstream targets phosphorylations. ( Koh, PO, 2011) |
| "Melatonin treatment reversed all these oxidant and antioxidant parameters to control values as well as serum liver enzymes." | 1.35 | Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus. ( Fadillioglu, E; Gursul, C; Iraz, M; Kurcer, Z; Parlakpinar, H, 2008) |
| "Melatonin treatment (50 mg/kg/daily, i." | 1.35 | Melatonin downregulates nuclear erythroid 2-related factor 2 and nuclear factor-kappaB during prevention of oxidative liver injury in a dimethylnitrosamine model. ( Hong, SS; Hong, SW; Jung, KH; Lee, DH; Zheng, HM, 2009) |
| "The prognosis of acute pancreatitis (AP) depends upon the degree of pancreatic necrosis and the intensity of multisystem organ failure." | 1.35 | Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis. ( Eşrefoğlu, M; Gül, M; Turan, F, 2008) |
| "Melatonin (Mel) has been successfully used as a potent antioxidant against many pathophysiological states." | 1.33 | Protective role of melatonin in cyclosporine A-induced oxidative stress in rat liver. ( Bianchi, R; Buffoli, B; Rezzani, R; Rodella, L; Stacchiotti, A, 2005) |
| "Melatonin co-treatment to the lead-administered rats attenuated the increase of LPO and restored the activity of SOD and levels of GSH as well as the mean values of NA, NV and N/C." | 1.33 | Melatonin protects against lead-induced hepatic and renal toxicity in male rats. ( Abdel-Rahman, GH; El-Sokkary, GH; Kamel, ES, 2005) |
| "Melatonin treatment counteracted these alterations in young and aged septic rats." | 1.33 | Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in rats: effects of melatonin treatment. ( Acuña-Castroviejo, D; Escames, G; López, LC; Ortiz, F; Ros, E, 2006) |
| "Treatment with melatonin (3 mg/kg/daily, i." | 1.32 | Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats. ( Aeed, H; Avinoach, I; Avni, Y; Bruck, R; Hochman, A; Matas, Z; Shahmurov, M; Shirin, H; Weizman, N; Zozulya, G, 2004) |
| "Melatonin treatment was found to increase liver GSH-Px and GST activities in mice fed an HC diet." | 1.32 | Melatonin improved the disturbances in hepatic prooxidant and antioxidant balance and hepatotoxicity induced by a high cholesterol diet in C57BL/6J mice. ( Balkan, J; Cevikbaş, U; Keyer-Uysal, M; Sener, G; Uysal, M, 2004) |
| "Treatment with melatonin completely reversed this effect." | 1.29 | Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats. ( Attia, AM; Burgos, A; Hara, M; Melchiorri, D; Nistico, G; Reiter, RJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.00) | 18.7374 |
| 1990's | 3 (6.00) | 18.2507 |
| 2000's | 19 (38.00) | 29.6817 |
| 2010's | 21 (42.00) | 24.3611 |
| 2020's | 5 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yalcin, B | 1 |
| Yay, AH | 1 |
| Tan, FC | 1 |
| Özdamar, S | 1 |
| Yildiz, OG | 1 |
| Baiocchi, L | 1 |
| Zhou, T | 2 |
| Liangpunsakul, S | 1 |
| Ilaria, L | 1 |
| Milana, M | 1 |
| Meng, F | 2 |
| Kennedy, L | 2 |
| Kusumanchi, P | 1 |
| Yang, Z | 1 |
| Ceci, L | 1 |
| Glaser, S | 2 |
| Francis, H | 2 |
| Alpini, G | 2 |
| Sato, K | 1 |
| Wu, N | 1 |
| Chen, L | 1 |
| Franchitto, A | 1 |
| Onori, P | 1 |
| Gaudio, E | 1 |
| Mohamed, DZ | 1 |
| El-Sisi, AEE | 1 |
| Sokar, SS | 1 |
| Shebl, AM | 1 |
| Abu-Risha, SE | 1 |
| Novais, AA | 1 |
| Chuffa, LGA | 1 |
| Zuccari, DAPC | 1 |
| Reiter, RJ | 5 |
| Marjot, T | 1 |
| Ray, DW | 1 |
| Williams, FR | 1 |
| Tomlinson, JW | 1 |
| Armstrong, MJ | 1 |
| Zhang, JJ | 1 |
| Meng, X | 1 |
| Li, Y | 2 |
| Zhou, Y | 2 |
| Xu, DP | 1 |
| Li, S | 1 |
| Li, HB | 1 |
| Bonomini, F | 1 |
| Borsani, E | 1 |
| Favero, G | 1 |
| Rodella, LF | 1 |
| Rezzani, R | 2 |
| Luo, C | 1 |
| Yang, Q | 1 |
| Liu, Y | 1 |
| Zhou, S | 1 |
| Jiang, J | 1 |
| Bhattacharya, P | 1 |
| Cui, Y | 1 |
| Yang, H | 1 |
| Ma, H | 1 |
| Yao, J | 1 |
| Lawler, SE | 1 |
| Zhang, X | 1 |
| Fu, J | 1 |
| Rozental, R | 1 |
| Aly, H | 1 |
| Johnson, MD | 1 |
| Chiocca, EA | 1 |
| Wang, X | 1 |
| Esmaeili, A | 1 |
| Namazi, S | 1 |
| Yildirim, A | 1 |
| Arabacı Tamer, S | 1 |
| Sahin, D | 1 |
| Bagriacik, F | 1 |
| Kahraman, MM | 1 |
| Onur, ND | 1 |
| Cayirli, YB | 1 |
| Cilingir Kaya, ÖT | 1 |
| Aksu, B | 1 |
| Akdeniz, E | 1 |
| Yuksel, M | 1 |
| Çetinel, Ş | 2 |
| Yeğen, BÇ | 1 |
| Chojnacki, C | 1 |
| Walecka-Kapica, E | 1 |
| Romanowski, M | 1 |
| Chojnacki, J | 1 |
| Klupinska, G | 1 |
| Yang, Y | 1 |
| Feng, Y | 1 |
| Yan, J | 1 |
| Fan, C | 1 |
| Jiang, S | 1 |
| Qu, Y | 1 |
| Djordjevic, B | 1 |
| Sokolovic, D | 1 |
| Kocic, G | 1 |
| Veljkovic, A | 1 |
| Despotovic, M | 1 |
| Basic, J | 1 |
| Jevtovic-Stoimenov, T | 1 |
| Sokolovic, DM | 1 |
| Esteban-Zubero, E | 1 |
| Alatorre-Jiménez, MA | 1 |
| López-Pingarrón, L | 1 |
| Reyes-Gonzales, MC | 1 |
| Almeida-Souza, P | 1 |
| Cantín-Golet, A | 1 |
| Ruiz-Ruiz, FJ | 1 |
| Tan, DX | 1 |
| García, JJ | 1 |
| Chen, HH | 1 |
| Chen, YT | 1 |
| Yang, CC | 1 |
| Chen, KH | 3 |
| Sung, PH | 1 |
| Chiang, HJ | 1 |
| Chen, CH | 1 |
| Chua, S | 1 |
| Chung, SY | 1 |
| Chen, YL | 1 |
| Huang, TH | 1 |
| Kao, GS | 1 |
| Chen, SY | 1 |
| Lee, MS | 1 |
| Yip, HK | 1 |
| Sheen, JM | 1 |
| Chen, YC | 1 |
| Hsu, MH | 1 |
| Tain, YL | 1 |
| Huang, YH | 1 |
| Tiao, MM | 1 |
| Li, SW | 1 |
| Huang, LT | 1 |
| Hsu, JT | 2 |
| Le, PH | 1 |
| Lin, CJ | 2 |
| Chen, TH | 3 |
| Kuo, CJ | 2 |
| Chiang, KC | 1 |
| Yeh, TS | 2 |
| Fadillioglu, E | 1 |
| Kurcer, Z | 1 |
| Parlakpinar, H | 1 |
| Iraz, M | 2 |
| Gursul, C | 1 |
| Li, JY | 1 |
| Yin, HZ | 1 |
| Gu, X | 1 |
| Zhang, WH | 1 |
| Qin, YM | 1 |
| Jung, KH | 1 |
| Hong, SW | 1 |
| Zheng, HM | 1 |
| Lee, DH | 1 |
| Hong, SS | 1 |
| Koh, PO | 1 |
| Esrefoglu, M | 2 |
| Ates, B | 1 |
| Gul, M | 2 |
| Chiu, MH | 1 |
| Su, CL | 2 |
| Chen, CF | 2 |
| Wang, D | 2 |
| Wang, JJ | 3 |
| Yeh, JH | 1 |
| Wang, F | 1 |
| Hwang, TL | 1 |
| Jan, YY | 1 |
| Baxi, DB | 1 |
| Singh, PK | 1 |
| Vachhrajani, KD | 1 |
| Ramachandran, AV | 1 |
| Aktas, C | 1 |
| Kanter, M | 1 |
| Erboga, M | 1 |
| Mete, R | 1 |
| Oran, M | 1 |
| Bülbüller, N | 1 |
| Akkuş, MA | 1 |
| Cetinkaya, Z | 1 |
| Ilhan, YS | 1 |
| Ozercan, I | 1 |
| Kirkil, C | 1 |
| Doğru, O | 1 |
| Chen, JC | 1 |
| Ng, CJ | 1 |
| Chiu, TF | 1 |
| Chen, HM | 1 |
| Koc, M | 1 |
| Taysi, S | 1 |
| Buyukokuroglu, ME | 1 |
| Bakan, N | 1 |
| Bruck, R | 1 |
| Aeed, H | 1 |
| Avni, Y | 1 |
| Shirin, H | 1 |
| Matas, Z | 1 |
| Shahmurov, M | 1 |
| Avinoach, I | 1 |
| Zozulya, G | 1 |
| Weizman, N | 1 |
| Hochman, A | 1 |
| Wang, H | 1 |
| Wei, W | 1 |
| Shen, YX | 1 |
| Dong, C | 1 |
| Zhang, LL | 1 |
| Wang, NP | 1 |
| Yue, L | 1 |
| Xu, SY | 1 |
| Balkan, J | 1 |
| Sener, G | 3 |
| Cevikbaş, U | 1 |
| Keyer-Uysal, M | 1 |
| Uysal, M | 1 |
| Contuk, G | 1 |
| Ercan, F | 2 |
| Cikler, E | 1 |
| Túnez, I | 1 |
| Muñoz, MC | 1 |
| Villavicencio, MA | 1 |
| Medina, FJ | 1 |
| de Prado, EP | 1 |
| Espejo, I | 1 |
| Barcos, M | 1 |
| Salcedo, M | 1 |
| Feijóo, M | 1 |
| Montilla, P | 1 |
| Buffoli, B | 1 |
| Rodella, L | 1 |
| Stacchiotti, A | 1 |
| Bianchi, R | 1 |
| El-Sokkary, GH | 1 |
| Abdel-Rahman, GH | 1 |
| Kamel, ES | 1 |
| Sert, G | 1 |
| Ozer Sehirli, A | 1 |
| Arbak, S | 1 |
| Gedik, N | 1 |
| Ayanoğlu-Dülger, G | 1 |
| Guven, A | 1 |
| Yavuz, O | 1 |
| Cam, M | 1 |
| Bukan, N | 1 |
| Comunoglu, C | 1 |
| Gokce, F | 1 |
| Sulaiman, AA | 1 |
| Al-Shawi, NN | 1 |
| Jwaied, AH | 1 |
| Mahmood, DM | 1 |
| Hussain, SA | 1 |
| Escames, G | 1 |
| López, LC | 1 |
| Ortiz, F | 1 |
| Ros, E | 1 |
| Acuña-Castroviejo, D | 1 |
| Turan, F | 1 |
| Huang, H | 1 |
| Yin, R | 1 |
| Zhu, J | 1 |
| Feng, X | 1 |
| Wang, C | 1 |
| Sheng, Y | 1 |
| Dong, G | 1 |
| Li, D | 1 |
| Jing, H | 1 |
| Iguchi, H | 1 |
| Melchiorri, D | 2 |
| Attia, AM | 1 |
| Hara, M | 1 |
| Burgos, A | 1 |
| Nistico, G | 1 |
| Sewerynek, E | 1 |
| Ortiz, GG | 1 |
| Lewinski, A | 1 |
| Cuzzocrea, S | 1 |
| Zingarelli, B | 1 |
| Costantino, G | 1 |
| Caputi, AP | 1 |
| Cotrozzi, G | 1 |
| Relli, P | 1 |
| Amico, A | 1 |
| Betti, L | 1 |
| Lupi, R | 1 |
11 reviews available for melatonin and Liver Diseases
| Article | Year |
|---|---|
Possible application of melatonin treatment in human diseases of the biliary tract.
Topics: Animals; Antioxidants; Biliary Tract Diseases; Central Nervous System Depressants; Humans; Liver Dis | 2019 |
Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies.
Topics: Animals; Circadian Rhythm; Humans; Liver Diseases; Melatonin | 2020 |
Exosomes and Melatonin: Where Their Destinies Intersect.
Topics: Animals; Brain Diseases; Colitis; Exosomes; Humans; Kidney Diseases; Liver Diseases; Melatonin; Neop | 2021 |
Sleep and liver disease: a bidirectional relationship.
Topics: Body Temperature Regulation; Case-Control Studies; Chronic Disease; Cost of Illness; Disease Progres | 2021 |
Effects of Melatonin on Liver Injuries and Diseases.
Topics: Animals; Apoptosis; Autophagy; Humans; Liver; Liver Diseases; Melatonin | 2017 |
Dietary Melatonin Supplementation Could Be a Promising Preventing/Therapeutic Approach for a Variety of Liver Diseases.
Topics: Animals; Dietary Supplements; Humans; Inflammation Mediators; Liver; Liver Diseases; Melatonin; Mito | 2018 |
The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health.
Topics: Animals; Brain Injuries; Humans; Liver Diseases; Melatonin; Neuroprotective Agents; Osteoporosis; Ox | 2019 |
Protective role of melatonin in liver damage.
Topics: Humans; Liver Diseases; Melatonin; Reactive Oxygen Species | 2014 |
A review of melatonin in hepatic ischemia/reperfusion injury and clinical liver disease.
Topics: Antioxidants; Endothelium; Humans; Liver; Liver Diseases; Melatonin; Mitochondria; Reperfusion Injur | 2014 |
Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review.
Topics: Aflatoxins; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hum | 2016 |
[The most frequent hormonal disorders found in chronic hepatopathy].
Topics: Adrenocorticotropic Hormone; Brain; Calcifediol; Calcium; Chronic Disease; Estradiol; Estrogens; Fem | 1985 |
1 trial available for melatonin and Liver Diseases
| Article | Year |
|---|---|
Effects of melatonin and lactulose on the liver and kidneys in rats with obstructive jaundice.
Topics: Analysis of Variance; Animals; Cholestasis; Cholesterol; Kidney Diseases; Lactulose; Liver; Liver Di | 2002 |
38 other studies available for melatonin and Liver Diseases
| Article | Year |
|---|---|
Investigation of the anti-oxidative and anti-inflammatory effects of melatonin on experimental liver damage by radiation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 3; Liver; Liver Diseases; Malondialdehyde; | 2023 |
Targeting autophagy to modulate hepatic ischemia/reperfusion injury: A comparative study between octreotide and melatonin as autophagy modulators through AMPK/PI3K/AKT/mTOR/ULK1 and Keap1/Nrf2 signaling pathways in rats.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Autophagy-Re | 2021 |
Is melatonin effective for pruritus caused by liver disease?
Topics: Animals; Cholestasis; Dermatitis, Atopic; Humans; Liver Diseases; Lysophospholipids; Melatonin; Mice | 2018 |
The effects of antibiotics and melatonin on hepato-intestinal inflammation and gut microbial dysbiosis induced by a short-term high-fat diet consumption in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Colon; Diet, High-Fat; Disease Models, Animal; Dysbios | 2019 |
The effect of melatonin on the liver of rats exposed to microwave radiation.
Topics: Animals; Antioxidants; Catalase; Dose-Response Relationship, Radiation; Lipid Peroxidation; Liver Di | 2015 |
Melatonin pretreatment enhances the therapeutic effects of exogenous mitochondria against hepatic ischemia-reperfusion injury in rats through suppression of mitochondrial permeability transition.
Topics: Animals; Apoptosis; Gene Expression Regulation; Liver; Liver Diseases; Male; Melatonin; Mitochondria | 2016 |
Melatonin Alleviates Liver Apoptosis in Bile Duct Ligation Young Rats.
Topics: Animals; Apoptosis; Bile Ducts; Endoplasmic Reticulum; Hep G2 Cells; Humans; Liver; Liver Diseases; | 2016 |
Mechanism of salutary effects of melatonin-mediated liver protection after trauma-hemorrhage: p38 MAPK-dependent iNOS/HIF-1α pathway.
Topics: Animals; Antioxidants; Cytokines; Enzyme Inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit; Imid | 2017 |
Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Diabetes Mellitu | 2008 |
Melatonin protects liver from intestine ischemia reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Intercellular Adhesion Mol | 2008 |
Melatonin downregulates nuclear erythroid 2-related factor 2 and nuclear factor-kappaB during prevention of oxidative liver injury in a dimethylnitrosamine model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Down-Regulation; Glutathione P | 2009 |
Melatonin prevents hepatic injury-induced decrease in Akt downstream targets phosphorylations.
Topics: 14-3-3 Proteins; Animals; Antioxidants; Apoptosis; bcl-Associated Death Protein; Dose-Response Relat | 2011 |
Melatonin and CAPE are able to prevent the liver from oxidative damage in rats: an ultrastructural and biochemical study.
Topics: Age Factors; Animals; Antioxidants; Caffeic Acids; Catalase; Glutathione; Glutathione Peroxidase; Li | 2012 |
Protective effect of melatonin on liver ischemia-reperfusion induced pulmonary microvascular injury in rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Capillary Permeability; Cytoprotection; Disease Models, An | 2012 |
Liver reperfusion-induced decrease in dynamic compliance and increase in airway resistance are ameliorated by preischemic treatment with melatonin through scavenging hydroxyl radicals in rat lungs.
Topics: Acute Lung Injury; Airway Resistance; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bi | 2012 |
Preischemic treatment with melatonin attenuates liver reperfusion-induced impairment of cardiac function.
Topics: Animals; Antioxidants; Biomarkers; Cardiac Catheterization; Creatine Kinase, MB Form; Disease Models | 2012 |
Melatonin prevents hemorrhagic shock-induced liver injury in rats through an Akt-dependent HO-1 pathway.
Topics: Adenosine Triphosphate; Alanine Transaminase; Androstadienes; Animals; Aspartate Aminotransferases; | 2012 |
Melatonin supplementation in rat ameliorates ovariectomy-induced oxidative stress.
Topics: Animals; Ascorbic Acid; Catalase; Corticosterone; Estrogen Replacement Therapy; Estrogens; Female; G | 2013 |
Melatonin attenuates oxidative stress, liver damage and hepatocyte apoptosis after bile-duct ligation in rats.
Topics: Animals; Apoptosis; Cell Proliferation; Cholestasis; Common Bile Duct; Fibrosis; Glutathione; Hepato | 2014 |
Altered neutrophil apoptosis activity is reversed by melatonin in liver ischemia-reperfusion.
Topics: Apoptosis; CD18 Antigens; Cells, Cultured; Cholecystectomy, Laparoscopic; Hepatectomy; Humans; Ische | 2003 |
Melatonin protects rat liver against irradiation-induced oxidative injury.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Glutathione Peroxidase; Liver; Liver Diseas | 2003 |
Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats.
Topics: Ammonia; Animals; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Liver; Liver Dise | 2004 |
Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cells, Cultured; Free Radical Scavengers | 2004 |
Melatonin improved the disturbances in hepatic prooxidant and antioxidant balance and hepatotoxicity induced by a high cholesterol diet in C57BL/6J mice.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Cholesterol, Dietary; Diet; Glutathione; Glu | 2004 |
Role of melatonin in reducing water avoidance stress-induced degeneration of the liver.
Topics: Acute Disease; Animals; Avoidance Learning; Chronic Disease; Free Radical Scavengers; Glutathione; L | 2005 |
Hepato- and neurotoxicity induced by thioacetamide: protective effects of melatonin and dimethylsulfoxide.
Topics: Alanine Transaminase; Ammonia; Animals; Blood Urea Nitrogen; Brain; Catalase; Chemical and Drug Indu | 2005 |
Protective role of melatonin in cyclosporine A-induced oxidative stress in rat liver.
Topics: Animals; Antioxidants; Chaperonin 60; Chemical and Drug Induced Liver Injury; Cyclosporine; Glutathi | 2005 |
Melatonin protects against lead-induced hepatic and renal toxicity in male rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Glutathione; Histocytochemistry; Karyometry; Kidney | 2005 |
Melatonin protects against pressure ulcer-induced oxidative injury of the skin and remote organs in rats.
Topics: Administration, Topical; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitr | 2006 |
Effects of melatonin on streptozotocin-induced diabetic liver injury in rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia; L | 2006 |
Protective effect of melatonin against chlorpromazine-induced liver disease in rats.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chlorpromazine; Disease Models, Anima | 2006 |
Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in rats: effects of melatonin treatment.
Topics: Aging; Animals; Antioxidants; Endotoxemia; Enzyme Induction; Injections; Kidney Diseases; Lipid Pero | 2006 |
Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis.
Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Arginine; Ascorbic Acid; Ceruletide; Female; L | 2008 |
Exogenous melatonin ameliorates hepatic injury in a rat cardiopulmonary bypass model.
Topics: Animals; Apoptosis; Carbon Dioxide; Cardiopulmonary Bypass; Disease Models, Animal; Dose-Response Re | 2008 |
[Age dependent changes in the serum melatonin concentrations in healthy human subjects and in patients with endocrine and hepatic disorders and renal failure (author's transl)].
Topics: Adolescent; Adult; Age Factors; Aged; Endocrine System Diseases; Female; Humans; Kidney Diseases; Li | 1981 |
Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats.
Topics: Aldehydes; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutat | 1995 |
Lipopolysaccharide-induced hepatotoxicity is inhibited by the antioxidant melatonin.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Escherichia coli; Glutathione; Lipid | 1995 |
Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat.
Topics: Acute Disease; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chemotaxis, Leukocyte; | 1998 |