Page last updated: 2024-10-19

melatonin and Liver Diseases, Alcoholic

melatonin has been researched along with Liver Diseases, Alcoholic in 7 studies

Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
"Melatonin plays a crucial role in regulating diverse physiological functions and metabolic homeostasis."1.46Melatonin ameliorates alcohol-induced bile acid synthesis by enhancing miR-497 expression. ( Chung, MJ; Elfadl, AK; Harris, RA; Hwang, SL; Jeong, KS; Kim, HM; Kim, YD; Lee, EJ; Lee, SE; Nedumaran, B, 2017)
"Treatment with melatonin significantly attenuated the increased level of serum aminotransferase, reduced the severe extent of hepatic cell damage, steatosis and the immigration of inflammatory cells, but had no effects on hepatic expression of lipogenic genes."1.35Melatonin protects against alcoholic liver injury by attenuating oxidative stress, inflammatory response, and apoptosis. ( Hu, S; Huang, D; Jiang, X; Shen, G; Yin, S, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Lee, SE2
Koh, H1
Joo, DJ1
Nedumaran, B2
Jeon, HJ1
Park, CS1
Harris, RA2
Kim, YD2
Marjot, T1
Ray, DW1
Williams, FR1
Tomlinson, JW1
Armstrong, MJ1
Swanson, GR1
Gorenz, A1
Shaikh, M1
Desai, V1
Forsyth, C1
Fogg, L1
Burgess, HJ1
Keshavarzian, A2
Kawada, T1
Swanson, G1
Rizvydeen, M1
Burgess, H1
Hwang, SL1
Lee, EJ1
Kim, HM1
Chung, MJ1
Elfadl, AK1
Jeong, KS1
Hu, S1
Yin, S1
Jiang, X1
Huang, D1
Shen, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Remote Physiologic Monitoring to Detect Inflammatory Bowel Disease (IBD) Flares: A Feasibility Study[NCT04333810]8 participants (Actual)Observational2020-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for melatonin and Liver Diseases, Alcoholic

ArticleYear
Sleep and liver disease: a bidirectional relationship.
    The lancet. Gastroenterology & hepatology, 2021, Volume: 6, Issue:10

    Topics: Body Temperature Regulation; Case-Control Studies; Chronic Disease; Cost of Illness; Disease Progres

2021

Other Studies

6 other studies available for melatonin and Liver Diseases, Alcoholic

ArticleYear
Induction of SIRT1 by melatonin improves alcohol-mediated oxidative liver injury by disrupting the CRBN-YY1-CYP2E1 signaling pathway.
    Journal of pineal research, 2020, Volume: 68, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cytochrome P-450 CYP2E1; Humans; Liver Diseases, Alco

2020
Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Jun-15, Volume: 308, Issue:12

    Topics: Acute-Phase Proteins; Adult; Aged; Aged, 80 and over; Carrier Proteins; Cell Membrane Permeability;

2015
Sleep parameters by actigraphy and relationship between plasma melatonin and intestinal permeability in alcoholics.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Aug-15, Volume: 309, Issue:4

    Topics: Cell Membrane Permeability; Endotoxemia; Female; Humans; Intestinal Absorption; Intestinal Mucosa; L

2015
Response to Dr. Kawada.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Aug-15, Volume: 309, Issue:4

    Topics: Cell Membrane Permeability; Endotoxemia; Female; Humans; Intestinal Absorption; Intestinal Mucosa; L

2015
Melatonin ameliorates alcohol-induced bile acid synthesis by enhancing miR-497 expression.
    Journal of pineal research, 2017, Volume: 62, Issue:2

    Topics: Animals; Antioxidants; Bile Acids and Salts; Blotting, Western; Chromatin Immunoprecipitation; Disea

2017
Melatonin protects against alcoholic liver injury by attenuating oxidative stress, inflammatory response, and apoptosis.
    European journal of pharmacology, 2009, Aug-15, Volume: 616, Issue:1-3

    Topics: Alcohols; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cytokines; Gene Expression Reg

2009