Page last updated: 2024-10-19

melatonin and Leukomalacia, Periventricular

melatonin has been researched along with Leukomalacia, Periventricular in 4 studies

Leukomalacia, Periventricular: Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

Research Excerpts

ExcerptRelevanceReference
"Melatonin treatment resulted in a slower recovery of fetal blood pressure following umbilical cord occlusion, but without changes in fetal heart rate, acid base status or mortality."1.34Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion. ( Gressens, P; Hagberg, H; Kjellmer, I; Lapatto, R; Mallard, C; Sultan, B; Svedin, P; Welin, AK, 2007)
"Periventricular leukomalacia is one of the main causes of cerebral palsy."1.31Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge. ( Bac, P; Evrard, P; Gressens, P; Husson, I; Mesplès, B; Vamecq, J, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yan, C1
Zhang, B1
McNally, MA1
Soul, JS1
Welin, AK1
Svedin, P1
Lapatto, R1
Sultan, B1
Hagberg, H1
Gressens, P2
Kjellmer, I1
Mallard, C1
Husson, I1
Mesplès, B1
Bac, P1
Vamecq, J1
Evrard, P1

Reviews

1 review available for melatonin and Leukomalacia, Periventricular

ArticleYear
Pharmacologic Prevention and Treatment of Neonatal Brain Injury.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Adrenal Cortex Hormones; Allopurinol; Anesthetics, Inhalation; Anticonvulsants; Antioxidants; Cerebr

2019

Other Studies

3 other studies available for melatonin and Leukomalacia, Periventricular

ArticleYear
Clinical significance of detecting serum melatonin and SBDPs in brain injury in preterm infants.
    Pediatrics and neonatology, 2019, Volume: 60, Issue:4

    Topics: Brain; Brain Injuries; Case-Control Studies; Cerebral Infarction; Cerebral Intraventricular Hemorrha

2019
Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion.
    Pediatric research, 2007, Volume: 61, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Asphyxia; Blood Gas Analysis; Blood Pressure; Brain; Cell Death;

2007
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge.
    Annals of neurology, 2002, Volume: 51, Issue:1

    Topics: Animals; Animals, Newborn; Antioxidants; Cell Death; Cerebral Palsy; Cystine; Denervation; Disease M

2002