melatonin has been researched along with Leucocythaemia in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied the combined effect of MEL and drugs from different pharmacological groups, such as cytarabine (CYT) and navitoclax (ABT-737), on the state of the pool of acute myeloid leukemia (AML) tumor cell using the MV4-11 cell line as model." | 8.31 | Melatonin Can Enhance the Effect of Drugs Used in the Treatment of Leukemia. ( Baburina, YL; Fadeev, RS; Kobyakova, MI; Krestinin, RR; Krestinina, OV; Lomovskaya, YV; Lomovsky, AI; Sotnikova, LD, 2023) |
| "Thus, finding new treatments for leukemia is essential." | 6.66 | Melatonin: A promising agent targeting leukemia. ( Asemi, Z; Mirzaei, H; Shafabakhsh, R, 2020) |
| "Melatonin has been proven to exert anti-tumor activity, but the effect of melatonin on MLL-r leukemia and the underlying mechanism remain poorly understood." | 5.51 | Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways. ( Deng, W; Huang, LB; Huang, W; Ke, ZY; Li, Y; Liang, C; Liu, XJ; Luo, JS; Luo, XQ; Peng, CJ; Qin, G; Sun, X; Tang, WY; Tang, YL; Wang, LN; Zhang, XL, 2019) |
| "Melatonin is an endogenous indoleamine with a wide range of biological functions." | 5.43 | Melatonin enhances hyperthermia-induced apoptotic cell death in human leukemia cells. ( Cabrera, J; Estévez, F; Loro, JF; Perdomo, J; Quintana, C; Quintana, J; Reiter, RJ, 2016) |
| "Melatonin is a naturally occurring indoleamine synthesized in the pineal gland that exhibits an extensive repertoire of biological activities." | 5.39 | Melatonin induces apoptosis through a caspase-dependent but reactive oxygen species-independent mechanism in human leukemia Molt-3 cells. ( Cabrera, J; Estévez, F; Loro, J; Perdomo, J; Quintana, J; Reiter, RJ, 2013) |
| "Melatonin treatment was not associated with significant cytotoxicity in HL-60 cells, although the generation of ROS was significantly increased." | 5.33 | Melatonin cytotoxicity in human leukemia cells: relation with its pro-oxidant effect. ( Buck, S; Büyükavci, M; Ozdemir, O; Ravindranath, Y; Savaşan, S; Stout, M, 2006) |
| "The so-called 'Melatonin Hypothesis' proposed that decreased nocturnal production of melatonin (MLT) might explain the increased risk of breast cancer that has been formerly attributed to extremely low-frequency (ELF) magnetic fields (MF) of weak intensity." | 4.88 | Health effects of extremely low-frequency magnetic fields: reconsidering the melatonin hypothesis in the light of current data on magnetoreception. ( Bouland, C; Burda, H; de Brouwer, C; Vanderstraeten, J; Verschaeve, L, 2012) |
| " We studied the combined effect of MEL and drugs from different pharmacological groups, such as cytarabine (CYT) and navitoclax (ABT-737), on the state of the pool of acute myeloid leukemia (AML) tumor cell using the MV4-11 cell line as model." | 4.31 | Melatonin Can Enhance the Effect of Drugs Used in the Treatment of Leukemia. ( Baburina, YL; Fadeev, RS; Kobyakova, MI; Krestinin, RR; Krestinina, OV; Lomovskaya, YV; Lomovsky, AI; Sotnikova, LD, 2023) |
| "Thus, finding new treatments for leukemia is essential." | 2.66 | Melatonin: A promising agent targeting leukemia. ( Asemi, Z; Mirzaei, H; Shafabakhsh, R, 2020) |
| "Melatonin has been proven to exert anti-tumor activity, but the effect of melatonin on MLL-r leukemia and the underlying mechanism remain poorly understood." | 1.51 | Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways. ( Deng, W; Huang, LB; Huang, W; Ke, ZY; Li, Y; Liang, C; Liu, XJ; Luo, JS; Luo, XQ; Peng, CJ; Qin, G; Sun, X; Tang, WY; Tang, YL; Wang, LN; Zhang, XL, 2019) |
| "Melatonin is an important regulator in human circadian rhythms and the sleep-wake cycle." | 1.48 | Melatonin secretion following brain midline irradiation is diminished, but not correlated with subjective sleep disturbances. ( Brabant, G; Clusmann, H; Gebauer, J; Kreitschmann-Andermahr, I; Piroth, M; Rosenkranz, E; Siegel, S; Thissen, A, 2018) |
| "Melatonin is an endogenous indoleamine with a wide range of biological functions." | 1.43 | Melatonin enhances hyperthermia-induced apoptotic cell death in human leukemia cells. ( Cabrera, J; Estévez, F; Loro, JF; Perdomo, J; Quintana, C; Quintana, J; Reiter, RJ, 2016) |
| "Melatonin is an indolamine that functions in the regulation of chronobiological rhythms to exert cytotoxic effects." | 1.42 | Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase. ( Asano, T; Narazaki, H; Yamanishi, M, 2015) |
| "Melatonin is a naturally occurring indoleamine synthesized in the pineal gland that exhibits an extensive repertoire of biological activities." | 1.39 | Melatonin induces apoptosis through a caspase-dependent but reactive oxygen species-independent mechanism in human leukemia Molt-3 cells. ( Cabrera, J; Estévez, F; Loro, J; Perdomo, J; Quintana, J; Reiter, RJ, 2013) |
| "Melatonin is an indolamine without relevant side effects." | 1.37 | Regulation of the expression of death receptors and their ligands by melatonin in haematological cancer cell lines and in leukaemia cells from patients. ( Antolín, I; Casado-Zapico, S; García-Pedrero, JM; García-Santos, G; Luño, E; Martín, V; Menendez, ST; Rodriguez, C; Rodríguez-Blanco, J; Sánchez-Sánchez, AM; Suárez, C, 2011) |
| "Melatonin treatment was not associated with significant cytotoxicity in HL-60 cells, although the generation of ROS was significantly increased." | 1.33 | Melatonin cytotoxicity in human leukemia cells: relation with its pro-oxidant effect. ( Buck, S; Büyükavci, M; Ozdemir, O; Ravindranath, Y; Savaşan, S; Stout, M, 2006) |
| "When melatonin was injected along with aracytin, it would significantly increase (P < 0." | 1.30 | Potential protective effects of melatonin on bone marrow of rats exposed to cytotoxic drugs. ( Anwar, MM; Mahfouz, HA; Sayed, AS, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Lomovsky, AI | 1 |
| Baburina, YL | 1 |
| Fadeev, RS | 1 |
| Lomovskaya, YV | 1 |
| Kobyakova, MI | 1 |
| Krestinin, RR | 1 |
| Sotnikova, LD | 1 |
| Krestinina, OV | 1 |
| Shafabakhsh, R | 1 |
| Mirzaei, H | 1 |
| Asemi, Z | 1 |
| Ng, MG | 1 |
| Ng, KY | 1 |
| Koh, RY | 1 |
| Chye, SM | 1 |
| Rosenkranz, E | 1 |
| Thissen, A | 1 |
| Siegel, S | 1 |
| Piroth, M | 1 |
| Clusmann, H | 1 |
| Gebauer, J | 1 |
| Brabant, G | 1 |
| Kreitschmann-Andermahr, I | 1 |
| Tang, YL | 1 |
| Sun, X | 1 |
| Huang, LB | 1 |
| Liu, XJ | 1 |
| Qin, G | 1 |
| Wang, LN | 1 |
| Zhang, XL | 1 |
| Ke, ZY | 1 |
| Luo, JS | 1 |
| Liang, C | 1 |
| Peng, CJ | 1 |
| Tang, WY | 1 |
| Li, Y | 1 |
| Huang, W | 1 |
| Luo, XQ | 1 |
| Deng, W | 1 |
| Zhou, B | 1 |
| Ye, H | 1 |
| Xing, C | 1 |
| Liang, B | 1 |
| Li, H | 1 |
| Chen, L | 1 |
| Huang, X | 1 |
| Wu, Y | 1 |
| Gao, S | 1 |
| Zheng, T | 1 |
| Fu, JJ | 1 |
| Hu, L | 1 |
| Qiu, F | 1 |
| Hu, M | 1 |
| Zhu, JJ | 1 |
| Hua, ZC | 1 |
| Wang, H | 1 |
| Perdomo, J | 2 |
| Cabrera, J | 2 |
| Estévez, F | 2 |
| Loro, J | 1 |
| Reiter, RJ | 2 |
| Quintana, J | 2 |
| Yamanishi, M | 1 |
| Narazaki, H | 1 |
| Asano, T | 1 |
| Quintana, C | 1 |
| Loro, JF | 1 |
| Casado-Zapico, S | 1 |
| Martín, V | 1 |
| García-Santos, G | 1 |
| Rodríguez-Blanco, J | 1 |
| Sánchez-Sánchez, AM | 1 |
| Luño, E | 1 |
| Suárez, C | 1 |
| García-Pedrero, JM | 1 |
| Menendez, ST | 1 |
| Antolín, I | 1 |
| Rodriguez, C | 1 |
| Vanderstraeten, J | 1 |
| Verschaeve, L | 1 |
| Burda, H | 1 |
| Bouland, C | 1 |
| de Brouwer, C | 1 |
| Büyükavci, M | 1 |
| Ozdemir, O | 1 |
| Buck, S | 1 |
| Stout, M | 1 |
| Ravindranath, Y | 1 |
| Savaşan, S | 1 |
| Henshaw, DL | 1 |
| Ward, JP | 1 |
| Matthews, JC | 1 |
| Anwar, MM | 1 |
| Mahfouz, HA | 1 |
| Sayed, AS | 1 |
| Smith, JA | 1 |
| Mee, TJ | 1 |
| Barnes, ND | 1 |
| Thorburn, RJ | 1 |
| Barnes, JL | 1 |
| Raĭkhlin, NT | 1 |
| Kvetnoĭ, IM | 1 |
4 reviews available for melatonin and Leucocythaemia
| Article | Year |
|---|---|
Melatonin: A promising agent targeting leukemia.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Cell Proliferation; DNA Damage; Gene Expr | 2020 |
Potential role of melatonin in prevention and treatment of leukaemia.
Topics: Animals; Apoptosis; Cell Proliferation; Disease Management; Humans; Leukemia; Melatonin; Outcome Ass | 2021 |
Health effects of extremely low-frequency magnetic fields: reconsidering the melatonin hypothesis in the light of current data on magnetoreception.
Topics: Animals; Breast Neoplasms; Circadian Rhythm; Environmental Exposure; Female; Humans; Leukemia; Magne | 2012 |
Can disturbances in the atmospheric electric field created by powerline corona ions disrupt melatonin production in the pineal gland?
Topics: Adult; Air Pollutants; Animals; Atmosphere; Child; Circadian Rhythm; Electromagnetic Fields; Humans; | 2008 |
13 other studies available for melatonin and Leucocythaemia
| Article | Year |
|---|---|
Melatonin Can Enhance the Effect of Drugs Used in the Treatment of Leukemia.
Topics: Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; Leukemia; Mel | 2023 |
Melatonin secretion following brain midline irradiation is diminished, but not correlated with subjective sleep disturbances.
Topics: Adolescent; Adult; Aged; Brain; Brain Neoplasms; Cross-Sectional Studies; Female; Humans; Leukemia; | 2018 |
Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways.
Topics: Animals; Antigens, Nuclear; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; Cyclooxyg | 2019 |
Targeting miR-193a-AML1-ETO-β-catenin axis by melatonin suppresses the self-renewal of leukaemia stem cells in leukaemia with t (8;21) translocation.
Topics: Animals; Apoptosis; beta Catenin; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Self Ren | 2019 |
Nanoarchitectured electrochemical cytosensors for selective detection of leukemia cells and quantitative evaluation of death receptor expression on cell surfaces.
Topics: Antioxidants; Biosensing Techniques; Carbon; Electrochemical Techniques; Electrodes; Ferric Compound | 2013 |
Melatonin induces apoptosis through a caspase-dependent but reactive oxygen species-independent mechanism in human leukemia Molt-3 cells.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 9; Cell Line, Tumor; Cytochromes c; Dru | 2013 |
Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Deoxy | 2015 |
Melatonin enhances hyperthermia-induced apoptotic cell death in human leukemia cells.
Topics: Apoptosis; Caspases; HL-60 Cells; Humans; Hypothermia, Induced; K562 Cells; Leukemia; Melatonin; Neo | 2016 |
Regulation of the expression of death receptors and their ligands by melatonin in haematological cancer cell lines and in leukaemia cells from patients.
Topics: Apoptosis; Blotting, Western; Caspase 3; Fas Ligand Protein; fas Receptor; HL-60 Cells; Humans; Leuk | 2011 |
Melatonin cytotoxicity in human leukemia cells: relation with its pro-oxidant effect.
Topics: Apoptosis; Cell Survival; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Jurkat Cells; Leuke | 2006 |
Potential protective effects of melatonin on bone marrow of rats exposed to cytotoxic drugs.
Topics: Acid Phosphatase; Adjuvants, Immunologic; Alkaline Phosphatase; Animals; Bone Marrow Cells; Cell Sur | 1998 |
Melatonin in serum and cerebrospinal fluid.
Topics: Child; Child, Preschool; Female; Humans; Leukemia; Male; Melatonin | 1976 |
[Dynamics of changes in enterochromaffin cells during tumor growth].
Topics: Chromaffin System; Enterochromaffin Cells; Gastrointestinal Neoplasms; Humans; Hyperplasia; Leukemia | 1976 |