melatonin has been researched along with Kidney Diseases in 66 studies
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our data suggest a potential therapeutic effect of combined therapy with melatonin, mesenchymal stem cells and their exosomes to minimize renal ischemia-reperfusion injury in rats." | 7.96 | Combination therapy with melatonin, stem cells and extracellular vesicles is effective in limiting renal ischemia-reperfusion injury in a rat model. ( El-Magd, MA; El-Taweel, F; Elkholy, SS; Ghozy, A; Zahran, R, 2020) |
| "Melatonin (N‑acetyl‑5‑methoxytryptamine; MT) has been shown to have a protective effect against sepsis‑induced renal injury, however, the mechanisms underlying the function of MT remain to be elucidated." | 7.91 | Melatonin prevents sepsis-induced renal injury via the PINK1/Parkin1 signaling pathway. ( Dai, W; Deng, Y; Hu, S; Huang, H; Si, L; Xu, L; Zhou, L, 2019) |
| "To evaluate the melatonin effects in these animals, we studied the renal cytoarchitecture by means of morphological analyses, immunofluorescence expression of specific markers related to fibrosis, oxidative stress, inflammation and apoptosis." | 7.88 | Oral supplementation of melatonin protects against lupus nephritis renal injury in a pristane-induced lupus mouse model. ( Bonomini, F; Dos Santos, M; Favero, G; Rezzani, R; Rodella, LF; Stacchiotti, A; Veronese, FV, 2018) |
| "Previous studies have indicated edema may be involved in the pathophysiology following hypoxic-ischemic encephalopathy (HIE), and melatonin may exhibit neuro-protection against brain insults." | 7.85 | Melatonin alleviates brain and peripheral tissue edema in a neonatal rat model of hypoxic-ischemic brain damage: the involvement of edema related proteins. ( Ding, X; Feng, X; Han, X; Li, YH; Liu, MH; Lv, Y; Sun, B; Wang, Y; Xu, LX, 2017) |
| "To investigate whether melatonin (MLT) treatment has any protective effect on unilateral ureteral obstruction (UUO)-induced kidney injury in rats." | 7.75 | Melatonin attenuates unilateral ureteral obstruction-induced renal injury by reducing oxidative stress, iNOS, MAPK, and NF-kB expression. ( Cekmen, M; Ilbey, YO; Ozbek, E; Ozbek, M; Simsek, A; Somay, A, 2009) |
| "The antioxidative effects of melatonin (Mel), 5-hydroxytryptophan (5-HTP) and taurine (TAU) on hyperglycemia-induced oxidative stress was investigated in primary cultures of kidney-cortex tubule cells grown in metabolically and hormonally defined medium." | 7.74 | Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury. ( Bryla, J; Derlacz, RA; Drozak, J; Piekutowska, A; Sliwinska, M; Winiarska, K, 2007) |
| "To determine the effects of melatonin combined with antibiotic administration on the suppression of renal scarring in an experimental pyelonephritis model." | 7.73 | Effects of melatonin on suppression of renal scarring in experimental model of pyelonephritis. ( Bahat, E; Cay, A; Cobanoglu, U; Imamoğlu, M; Karahan, C; Sarihan, H; Tosun, I, 2006) |
| "Fibrosis is a common occurrence following organ injury and failure." | 6.53 | Melatonin: the dawning of a treatment for fibrosis? ( Deng, C; Di, S; Fan, C; Hu, W; Jiang, S; Lv, J; Ma, Z; Reiter, RJ; Yan, X; Yang, Y, 2016) |
| "Melatonin treatment potently prevents BUO or BUO-R induced renal injury, which may be partially attributed to restoring the expression of AQPs and inhibition of inflammatory response, as well as preserving renal ultrastructural integrity." | 5.51 | Melatonin therapy protects against renal injury before and after release of bilateral ureteral obstruction in rats. ( Li, Z; Liu, X; Song, E; Sun, N; Wang, Y; Wen, J; Zhang, Z; Zheng, T, 2019) |
| "Both Melatonin and 1400W were efficient in ameliorating experimental I/R injury of the kidneys." | 5.35 | Comparison of the efficacy of melatonin and 1400W on renal ischemia/reperfusion injury: a role for inhibiting iNOS. ( Akgul, EO; Cayci, T; Cetiner, S; Ersoz, N; Guven, A; Korkmaz, A; Oztas, E; Turk, E; Uysal, B, 2009) |
| "Our data suggest a potential therapeutic effect of combined therapy with melatonin, mesenchymal stem cells and their exosomes to minimize renal ischemia-reperfusion injury in rats." | 3.96 | Combination therapy with melatonin, stem cells and extracellular vesicles is effective in limiting renal ischemia-reperfusion injury in a rat model. ( El-Magd, MA; El-Taweel, F; Elkholy, SS; Ghozy, A; Zahran, R, 2020) |
| "Melatonin (N‑acetyl‑5‑methoxytryptamine; MT) has been shown to have a protective effect against sepsis‑induced renal injury, however, the mechanisms underlying the function of MT remain to be elucidated." | 3.91 | Melatonin prevents sepsis-induced renal injury via the PINK1/Parkin1 signaling pathway. ( Dai, W; Deng, Y; Hu, S; Huang, H; Si, L; Xu, L; Zhou, L, 2019) |
| "To evaluate the melatonin effects in these animals, we studied the renal cytoarchitecture by means of morphological analyses, immunofluorescence expression of specific markers related to fibrosis, oxidative stress, inflammation and apoptosis." | 3.88 | Oral supplementation of melatonin protects against lupus nephritis renal injury in a pristane-induced lupus mouse model. ( Bonomini, F; Dos Santos, M; Favero, G; Rezzani, R; Rodella, LF; Stacchiotti, A; Veronese, FV, 2018) |
| "Previous studies have indicated edema may be involved in the pathophysiology following hypoxic-ischemic encephalopathy (HIE), and melatonin may exhibit neuro-protection against brain insults." | 3.85 | Melatonin alleviates brain and peripheral tissue edema in a neonatal rat model of hypoxic-ischemic brain damage: the involvement of edema related proteins. ( Ding, X; Feng, X; Han, X; Li, YH; Liu, MH; Lv, Y; Sun, B; Wang, Y; Xu, LX, 2017) |
| "To investigate whether melatonin (MLT) treatment has any protective effect on unilateral ureteral obstruction (UUO)-induced kidney injury in rats." | 3.75 | Melatonin attenuates unilateral ureteral obstruction-induced renal injury by reducing oxidative stress, iNOS, MAPK, and NF-kB expression. ( Cekmen, M; Ilbey, YO; Ozbek, E; Ozbek, M; Simsek, A; Somay, A, 2009) |
| "The antioxidative effects of melatonin (Mel), 5-hydroxytryptophan (5-HTP) and taurine (TAU) on hyperglycemia-induced oxidative stress was investigated in primary cultures of kidney-cortex tubule cells grown in metabolically and hormonally defined medium." | 3.74 | Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury. ( Bryla, J; Derlacz, RA; Drozak, J; Piekutowska, A; Sliwinska, M; Winiarska, K, 2007) |
| "To determine the effects of melatonin combined with antibiotic administration on the suppression of renal scarring in an experimental pyelonephritis model." | 3.73 | Effects of melatonin on suppression of renal scarring in experimental model of pyelonephritis. ( Bahat, E; Cay, A; Cobanoglu, U; Imamoğlu, M; Karahan, C; Sarihan, H; Tosun, I, 2006) |
| "Fibrosis is a common occurrence following organ injury and failure." | 2.53 | Melatonin: the dawning of a treatment for fibrosis? ( Deng, C; Di, S; Fan, C; Hu, W; Jiang, S; Lv, J; Ma, Z; Reiter, RJ; Yan, X; Yang, Y, 2016) |
| " These findings suggest that betaine and melatonin concomitant use is likely to provide greater protection against CP-induced nephrotoxicity than when they are given singly, rendering them potentially suitable and safe agents to use in clinical trials to assess their possible beneficial actions in cancer patients receiving CP." | 1.62 | The salutary action of melatonin and betaine, given singly or concomitantly, on cisplatin-induced nephrotoxicity in mice. ( Al Sabahi, M; Al Za'abi, M; Ali, BH; Ali, H, 2021) |
| " CP (6 mg/kg, given once intraperitoneally) induced nephrotoxicity as evidenced by several significant adverse physiological, biochemical and histopathological actions that included a reduction in body weight, increased urine production, and significant alterations in some conventional and novel renal damage indices in plasma, urine and kidneys." | 1.56 | Effect of concomitant treatment of curcumin and melatonin on cisplatin-induced nephrotoxicity in rats. ( Abdelrahman, A; Al Suleimani, Y; Al Za'abi, M; Ali, BH; Ali, H; Manoj, P; Nemmar, A, 2020) |
| "Melatonin treatment potently prevents BUO or BUO-R induced renal injury, which may be partially attributed to restoring the expression of AQPs and inhibition of inflammatory response, as well as preserving renal ultrastructural integrity." | 1.51 | Melatonin therapy protects against renal injury before and after release of bilateral ureteral obstruction in rats. ( Li, Z; Liu, X; Song, E; Sun, N; Wang, Y; Wen, J; Zhang, Z; Zheng, T, 2019) |
| "Docetaxel (DTX) has been used in cancer treatments for several decades, but it results in many adverse apoptotic effects through excessive production of reactive oxygen species (ROS) in some tissue including the kidney and testes." | 1.51 | Treatment with melatonin and selenium attenuates docetaxel-induced apoptosis and oxidative injury in kidney and testes of mice. ( Baş, E; Nazıroğlu, M, 2019) |
| "As melatonin is a natural antioxidant molecule, detailed pharmacokinetic and pharmacodynamic studies are expected to establish it as an effective nephro-protective agent in future." | 1.48 | Melatonin attenuates arsenic induced nephropathy via the regulation of oxidative stress and inflammatory signaling cascades in mice. ( Dutta, S; Mahalanobish, S; Sadhukhan, P; Saha, S; Sil, PC, 2018) |
| "Pretreatment with melatonin, a NFκB inhibitor attenuated TDF induced renal damage." | 1.46 | Role for NF-κB inflammatory signalling pathway in tenofovir disoproxil fumarate (TDF) induced renal damage in rats. ( Abraham, P; Isaac, B; Ramamoorthy, H; Selvakumar, D, 2017) |
| "Ciprofloxacin is a synthetic broad-spectrum antimicrobial agent of fluoroquinolone family." | 1.43 | Melatonin can attenuate ciprofloxacin induced nephrotoxicity: Involvement of nitric oxide and TNF-α. ( Ahangar, N; Ashari, S; Shaki, F, 2016) |
| "Melatonin treatment reversed the increase of serum TNF-α levels and histopathological injury in renal tissue after renal IR." | 1.42 | Effects of melatonin on the serum levels of pro-inflammatory cytokines and tissue injury after renal ischemia reperfusion in rats. ( Baba, F; Hekimoglu, A; Oguz, E; Ozbilge, H; Tabur, S; Yerer, MB; Yilmaz, Z, 2015) |
| " We aimed to investigate the effects of lycopene (Lyc) alone or combined with melatonin (Mel) on Mtx- induced nephrotoxicity since both of these agents have antioxidant and anti-inflammatory effects." | 1.42 | Effects of Lycopene Alone or Combined with Melatonin on Methotrexate-Induced Nephrotoxicity in Rats. ( Aksoy, N; Kocarslan, S; Oguz, E; Sezen, H; Tabur, S; Yilmaz, Z, 2015) |
| "Aluminum has toxic potential on humans and animals when it accumulates in various tissues." | 1.42 | Role of Exogenous Melatonin on Cell Proliferation and Oxidant/Antioxidant System in Aluminum-Induced Renal Toxicity. ( Arda-Pirincci, P; Bayrak, BB; Karabulut-Bulan, O; Sarikaya-Unal, G; Us, H; Yanardag, R, 2015) |
| "Both Melatonin and 1400W were efficient in ameliorating experimental I/R injury of the kidneys." | 1.35 | Comparison of the efficacy of melatonin and 1400W on renal ischemia/reperfusion injury: a role for inhibiting iNOS. ( Akgul, EO; Cayci, T; Cetiner, S; Ersoz, N; Guven, A; Korkmaz, A; Oztas, E; Turk, E; Uysal, B, 2009) |
| "Melatonin co-treatment to the lead-administered rats attenuated the increase of LPO and restored the activity of SOD and levels of GSH as well as the mean values of NA, NV and N/C." | 1.33 | Melatonin protects against lead-induced hepatic and renal toxicity in male rats. ( Abdel-Rahman, GH; El-Sokkary, GH; Kamel, ES, 2005) |
| "Amrinone was the most effective drug as judged on the basis of the pathological findings." | 1.33 | Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity. ( Akbulut, HH; Akpolat, N; Celik, I; Cihangiroglu, M; Ilhan, N, 2005) |
| "Melatonin treatment counteracted these alterations in young and aged septic rats." | 1.33 | Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in rats: effects of melatonin treatment. ( Acuña-Castroviejo, D; Escames, G; López, LC; Ortiz, F; Ros, E, 2006) |
| "Treatment with melatonin decreased lipid peroxides, and permitted a recovery of reduced glutathione, scavenger enzyme activity and parameters of renal function." | 1.32 | Melatonin effect on renal oxidative stress under constant light exposure. ( del Carmen Muñoz, M; Feijoo, M; Montilla, P; Rafael Muñoz-Castañeda, J; Túnez, I; Valdelvira, ME, 2003) |
| "Melatonin treatment reversed STZ-induced reduction of GSH-Px activity without having an effect on blood glucose." | 1.32 | Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats. ( Bukan, N; Cam, M; Ercan, F; Guven, A; Ustündag, N; Yavuz, O, 2003) |
| "Melatonin was injected i." | 1.31 | Effect of melatonin on hyperlipidemic nephropathy under constant light exposure. ( Bujalance-Arenas, L; Feijoo-López, AL; Montilla, P; Muñoz, MC; Túnez, L; Valdvira, E, 2002) |
| "Co-treatment with melatonin completely counteracted the effects of ALA." | 1.31 | Renal toxicity of the carcinogen delta-aminolevulinic acid: antioxidant effects of melatonin. ( Karbownik, M; Manchester, LC; Reiter, RJ; Tan, D, 2000) |
| "Treatment with melatonin significantly increased the serum total antioxidative activity and reduced the serum malondialdehyde concentration." | 1.31 | Protective effect of melatonin on renal injury of rats induced by bile duct ligation. ( Chen, CY; Chen, FF; Lin, XZ; Shiesh, SC; Tsao, HC, 2001) |
| "AD administration resulted in hyperlipidemia and high-grade proteinuria and a marked increase in serum lipoperoxides, urea, and creatinine." | 1.30 | Hyperlipidemic nephropathy induced by adriamycin: effect of melatonin administration. ( López, A; Montilla, P; Muñoz, MC; Soria, JV; Túnez, I, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.52) | 18.7374 |
| 1990's | 3 (4.55) | 18.2507 |
| 2000's | 28 (42.42) | 29.6817 |
| 2010's | 27 (40.91) | 24.3611 |
| 2020's | 7 (10.61) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, N | 1 |
| Wang, Y | 3 |
| Ma, Y | 1 |
| Liu, Y | 1 |
| Liu, Z | 1 |
| Dai, W | 1 |
| Huang, H | 2 |
| Si, L | 1 |
| Hu, S | 1 |
| Zhou, L | 1 |
| Xu, L | 1 |
| Deng, Y | 1 |
| Zhao, L | 1 |
| Hu, C | 1 |
| Zhang, P | 1 |
| Jiang, H | 1 |
| Chen, J | 1 |
| Kim, JY | 1 |
| Leem, J | 1 |
| Jeon, EJ | 1 |
| Li, N | 2 |
| Wang, Z | 2 |
| Gao, F | 1 |
| Lei, Y | 1 |
| Li, Z | 2 |
| Zahran, R | 1 |
| Ghozy, A | 1 |
| Elkholy, SS | 1 |
| El-Taweel, F | 1 |
| El-Magd, MA | 1 |
| Ali, BH | 2 |
| Abdelrahman, A | 1 |
| Al Suleimani, Y | 1 |
| Manoj, P | 1 |
| Ali, H | 2 |
| Nemmar, A | 1 |
| Al Za'abi, M | 2 |
| Al Sabahi, M | 1 |
| Novais, AA | 1 |
| Chuffa, LGA | 1 |
| Zuccari, DAPC | 1 |
| Reiter, RJ | 3 |
| Xu, LX | 1 |
| Lv, Y | 1 |
| Li, YH | 1 |
| Ding, X | 1 |
| Han, X | 1 |
| Liu, MH | 1 |
| Sun, B | 1 |
| Feng, X | 1 |
| Goudarzi, M | 1 |
| Khodayar, MJ | 1 |
| Hosseini Tabatabaei, SMT | 1 |
| Ghaznavi, H | 1 |
| Fatemi, I | 1 |
| Mehrzadi, S | 1 |
| Dos Santos, M | 1 |
| Favero, G | 1 |
| Bonomini, F | 1 |
| Stacchiotti, A | 1 |
| Rodella, LF | 1 |
| Veronese, FV | 1 |
| Rezzani, R | 1 |
| Fadda, LM | 1 |
| Mohamed, AM | 1 |
| Ali, HM | 1 |
| Hagar, H | 1 |
| Aldossari, M | 1 |
| Dutta, S | 1 |
| Saha, S | 1 |
| Mahalanobish, S | 1 |
| Sadhukhan, P | 1 |
| Sil, PC | 1 |
| Haghi-Aminjan, H | 1 |
| Farhood, B | 1 |
| Rahimifard, M | 1 |
| Didari, T | 1 |
| Baeeri, M | 1 |
| Hassani, S | 1 |
| Hosseini, R | 1 |
| Abdollahi, M | 1 |
| Li, J | 1 |
| Yan, S | 1 |
| Lu, Y | 1 |
| Miao, X | 1 |
| Gu, Z | 1 |
| Shao, Y | 1 |
| Sun, N | 1 |
| Liu, X | 1 |
| Song, E | 1 |
| Zhang, Z | 1 |
| Wen, J | 1 |
| Zheng, T | 1 |
| Baş, E | 1 |
| Nazıroğlu, M | 1 |
| Escribano, BM | 1 |
| Díaz-Moreno, A | 1 |
| Moreno, A | 1 |
| Tasset, I | 1 |
| Túnez, I | 3 |
| Zhang, M | 1 |
| Wang, T | 1 |
| Chen, HM | 1 |
| Chen, YQ | 1 |
| Deng, YC | 1 |
| Li, YT | 1 |
| Oguz, E | 2 |
| Yilmaz, Z | 2 |
| Ozbilge, H | 1 |
| Baba, F | 2 |
| Tabur, S | 2 |
| Yerer, MB | 1 |
| Hekimoglu, A | 1 |
| Karabulut-Bulan, O | 1 |
| Bayrak, BB | 1 |
| Arda-Pirincci, P | 1 |
| Sarikaya-Unal, G | 1 |
| Us, H | 1 |
| Yanardag, R | 1 |
| Kocarslan, S | 1 |
| Sezen, H | 1 |
| Aksoy, N | 1 |
| Qiao, YF | 1 |
| Guo, WJ | 1 |
| Li, L | 1 |
| Shao, S | 1 |
| Qiao, X | 1 |
| Shao, JJ | 1 |
| Zhang, Q | 1 |
| Li, RS | 1 |
| Wang, LH | 1 |
| Hu, W | 1 |
| Ma, Z | 1 |
| Jiang, S | 1 |
| Fan, C | 1 |
| Deng, C | 1 |
| Yan, X | 1 |
| Di, S | 1 |
| Lv, J | 1 |
| Yang, Y | 1 |
| Shaki, F | 1 |
| Ashari, S | 1 |
| Ahangar, N | 1 |
| Ramamoorthy, H | 1 |
| Abraham, P | 1 |
| Isaac, B | 1 |
| Selvakumar, D | 1 |
| Ozan, E | 2 |
| Sonmez, MF | 1 |
| Ozan, S | 1 |
| Colakoglu, N | 1 |
| Yilmaz, S | 1 |
| Kuloglu, T | 1 |
| Eybl, V | 1 |
| Kotyzová, D | 1 |
| Cerná, P | 1 |
| Koutensky, J | 1 |
| Zararsiz, I | 1 |
| Sarsilmaz, M | 1 |
| Tas, U | 1 |
| Kus, I | 1 |
| Meydan, S | 1 |
| Ilbey, YO | 2 |
| Ozbek, E | 2 |
| Cekmen, M | 2 |
| Somay, A | 2 |
| Ozcan, L | 1 |
| Otünctemur, A | 1 |
| Simsek, A | 2 |
| Mete, F | 1 |
| Zhang, J | 1 |
| Liu, H | 1 |
| Wang, C | 1 |
| Shen, Y | 1 |
| Li, D | 1 |
| Jing, H | 1 |
| Ozbek, M | 1 |
| Koch, BC | 1 |
| van der Putten, K | 1 |
| Van Someren, EJ | 1 |
| Wielders, JP | 1 |
| Ter Wee, PM | 1 |
| Nagtegaal, JE | 1 |
| Gaillard, CA | 1 |
| Ersoz, N | 1 |
| Guven, A | 2 |
| Cayci, T | 2 |
| Uysal, B | 2 |
| Turk, E | 1 |
| Oztas, E | 1 |
| Akgul, EO | 2 |
| Korkmaz, A | 2 |
| Cetiner, S | 1 |
| Malekinejad, H | 1 |
| Farshid, AA | 1 |
| Mirzakhani, N | 1 |
| Dzherieva, IS | 1 |
| Volkova, NI | 1 |
| Kunak, ZI | 1 |
| Macit, E | 1 |
| Yaren, H | 1 |
| Yaman, H | 1 |
| Cakir, E | 1 |
| Aydin, I | 1 |
| Turker, T | 1 |
| Kurt, YG | 1 |
| Ozcan, A | 1 |
| Isbilir, S | 1 |
| Kenar, L | 1 |
| Lee, IC | 1 |
| Kim, SH | 2 |
| Lee, SM | 1 |
| Baek, HS | 1 |
| Moon, C | 1 |
| Park, SC | 1 |
| Kim, HC | 1 |
| Kim, JC | 1 |
| Sinanoglu, O | 1 |
| Sezgin, G | 1 |
| Ozturk, G | 1 |
| Tuncdemir, M | 1 |
| Guney, S | 1 |
| Aksungar, FB | 1 |
| Yener, N | 1 |
| Baxi, DB | 1 |
| Singh, PK | 1 |
| Vachhrajani, KD | 1 |
| Ramachandran, AV | 1 |
| Túnez, L | 1 |
| Muñoz, MC | 2 |
| Feijoo-López, AL | 1 |
| Valdvira, E | 1 |
| Bujalance-Arenas, L | 1 |
| Montilla, P | 3 |
| del Carmen Muñoz, M | 1 |
| Feijoo, M | 1 |
| Valdelvira, ME | 1 |
| Rafael Muñoz-Castañeda, J | 1 |
| Bülbüller, N | 1 |
| Akkuş, MA | 1 |
| Cetinkaya, Z | 1 |
| Ilhan, YS | 1 |
| Ozercan, I | 1 |
| Kirkil, C | 1 |
| Doğru, O | 1 |
| Cam, M | 1 |
| Yavuz, O | 1 |
| Ercan, F | 1 |
| Bukan, N | 1 |
| Ustündag, N | 1 |
| Serel, TA | 1 |
| Ozguner, F | 1 |
| Soyupek, S | 1 |
| Pedreañez, A | 1 |
| Rincón, J | 1 |
| Romero, M | 1 |
| Viera, N | 1 |
| Mosquera, J | 1 |
| El-Sokkary, GH | 1 |
| Abdel-Rahman, GH | 1 |
| Kamel, ES | 1 |
| Celik, I | 1 |
| Cihangiroglu, M | 1 |
| Ilhan, N | 1 |
| Akpolat, N | 1 |
| Akbulut, HH | 1 |
| Sener, G | 1 |
| Sert, G | 1 |
| Ozer Sehirli, A | 1 |
| Arbak, S | 1 |
| Gedik, N | 1 |
| Ayanoğlu-Dülger, G | 1 |
| Imamoğlu, M | 1 |
| Cay, A | 1 |
| Cobanoglu, U | 1 |
| Bahat, E | 1 |
| Karahan, C | 1 |
| Tosun, I | 1 |
| Sarihan, H | 1 |
| Gazi, S | 1 |
| Altun, A | 1 |
| Erdogan, O | 1 |
| Ozturk, F | 1 |
| Ozturk, IC | 1 |
| Batcioglu, K | 1 |
| Vardi, N | 2 |
| Geron, R | 1 |
| Shurtz-Swirski, R | 1 |
| Sela, S | 1 |
| Gurevitch, Y | 1 |
| Tanasijtchouk, T | 1 |
| Orr, ZS | 1 |
| Shkolnik, G | 1 |
| Tanhilevski, O | 1 |
| Kristal, B | 1 |
| Escames, G | 1 |
| López, LC | 1 |
| Ortiz, F | 1 |
| Ros, E | 1 |
| Acuña-Castroviejo, D | 1 |
| Derlacz, RA | 1 |
| Sliwinska, M | 1 |
| Piekutowska, A | 1 |
| Winiarska, K | 1 |
| Drozak, J | 1 |
| Bryla, J | 1 |
| Kurcer, Z | 1 |
| Parlakpinar, H | 1 |
| Tasdemir, S | 1 |
| Iraz, M | 1 |
| Fadillioglu, E | 1 |
| Gül, M | 1 |
| Gultekin, F | 1 |
| Hicyilmaz, H | 1 |
| Iguchi, H | 1 |
| López, A | 1 |
| Soria, JV | 2 |
| Montilla, PL | 1 |
| Túnez, IF | 1 |
| Muñoz de Agueda, C | 1 |
| Gascón, FL | 1 |
| Kumar, KV | 1 |
| Naidu, MU | 1 |
| Shifow, AA | 1 |
| Prayag, A | 1 |
| Ratnakar, KS | 1 |
| Karbownik, M | 1 |
| Tan, D | 1 |
| Manchester, LC | 1 |
| Hara, M | 1 |
| Yoshida, M | 1 |
| Nishijima, H | 1 |
| Yokosuka, M | 1 |
| Iigo, M | 1 |
| Ohtani-Kaneko, R | 1 |
| Shimada, A | 1 |
| Hasegawa, T | 1 |
| Akama, Y | 1 |
| Hirata, K | 1 |
| Chen, CY | 1 |
| Shiesh, SC | 1 |
| Tsao, HC | 1 |
| Chen, FF | 1 |
| Lin, XZ | 1 |
| Longoni, B | 1 |
| Migliori, M | 1 |
| Ferretti, A | 1 |
| Origlia, N | 1 |
| Panichi, V | 1 |
| Boggi, U | 1 |
| Filippi, C | 1 |
| Cuttano, MG | 1 |
| Giovannini, L | 1 |
| Mosca, F | 1 |
6 reviews available for melatonin and Kidney Diseases
| Article | Year |
|---|---|
Melatonin preconditioning is an effective strategy for mesenchymal stem cell-based therapy for kidney disease.
Topics: Animals; Antioxidants; Humans; Kidney Diseases; Melatonin; Mesenchymal Stem Cell Transplantation; Me | 2020 |
Exosomes and Melatonin: Where Their Destinies Intersect.
Topics: Animals; Brain Diseases; Colitis; Exosomes; Humans; Kidney Diseases; Liver Diseases; Melatonin; Neop | 2021 |
The protective role of melatonin in chemotherapy-induced nephrotoxicity: a systematic review of non-clinical studies.
Topics: Animals; Antineoplastic Agents; Apoptosis; Humans; Inflammation; Kidney Diseases; Melatonin; Neoplas | 2018 |
Melatonin: the dawning of a treatment for fibrosis?
Topics: Animals; Extracellular Matrix; Fibrosis; Heart Diseases; Humans; Kidney Diseases; Liver Cirrhosis; M | 2016 |
[Arterial hypertension and metabolic disorders].
Topics: Circadian Rhythm; CLOCK Proteins; Depression; Humans; Hypertension; Hypertrophy, Left Ventricular; K | 2010 |
Renal deterioration caused by carcinogens as a consequence of free radical mediated tissue damage: a review of the protective action of melatonin.
Topics: Animals; Antioxidants; Carcinogens; Free Radical Scavengers; Free Radicals; Humans; Kidney; Kidney D | 2007 |
1 trial available for melatonin and Kidney Diseases
| Article | Year |
|---|---|
Effects of melatonin and lactulose on the liver and kidneys in rats with obstructive jaundice.
Topics: Analysis of Variance; Animals; Cholestasis; Cholesterol; Kidney Diseases; Lactulose; Liver; Liver Di | 2002 |
59 other studies available for melatonin and Kidney Diseases
| Article | Year |
|---|---|
Melatonin alleviates renal injury in diabetic rats by regulating autophagy.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Diabetes Mellitus, Experimental; Diabetes Mellitu | 2023 |
Melatonin prevents sepsis-induced renal injury via the PINK1/Parkin1 signaling pathway.
Topics: Animals; Apoptosis; Biomarkers; Biopsy; Cytokines; Disease Models, Animal; Immunohistochemistry; Inf | 2019 |
Protective Effects of Melatonin Against Aristolochic Acid-Induced Nephropathy in Mice.
Topics: Animals; Apoptosis; Aristolochic Acids; Cytokines; Humans; Kidney; Kidney Diseases; Male; Melatonin; | 2019 |
Melatonin ameliorates renal fibroblast-myofibroblast transdifferentiation and renal fibrosis through miR-21-5p regulation.
Topics: Actins; Animals; Biomarkers; Cell Survival; Cell Transdifferentiation; Disease Models, Animal; Disea | 2020 |
Combination therapy with melatonin, stem cells and extracellular vesicles is effective in limiting renal ischemia-reperfusion injury in a rat model.
Topics: Animals; Apoptosis; Female; Kidney; Kidney Diseases; Melatonin; Mesenchymal Stem Cells; Oxidative St | 2020 |
Effect of concomitant treatment of curcumin and melatonin on cisplatin-induced nephrotoxicity in rats.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cisplatin; Curcumin; Cytokines; Drug Therap | 2020 |
The salutary action of melatonin and betaine, given singly or concomitantly, on cisplatin-induced nephrotoxicity in mice.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Betaine; Cisplatin; Drug Therapy, Combination; | 2021 |
Melatonin alleviates brain and peripheral tissue edema in a neonatal rat model of hypoxic-ischemic brain damage: the involvement of edema related proteins.
Topics: Animals; Animals, Newborn; Biomarkers; Blotting, Western; Brain Edema; Colonic Diseases; Edema; Hypo | 2017 |
Pretreatment with melatonin protects against cyclophosphamide-induced oxidative stress and renal damage in mice.
Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Cyclophosphamide; Disease Models, Animal; | 2017 |
Oral supplementation of melatonin protects against lupus nephritis renal injury in a pristane-induced lupus mouse model.
Topics: Animals; Apoptosis; Autoantibodies; Cytokines; Disease Models, Animal; Female; Fibrosis; Inflammatio | 2018 |
Prophylactic administration of carnosine and melatonin abates the incidence of renal toxicity induced by an over dose of titanium dioxide nanoparticles.
Topics: Animals; Carnosine; Drug Overdose; Kidney Diseases; Male; Melatonin; Nanoparticles; Rats; Rats, Wist | 2018 |
Melatonin attenuates arsenic induced nephropathy via the regulation of oxidative stress and inflammatory signaling cascades in mice.
Topics: Animals; Arsenic; Inflammation; Kidney Diseases; Melatonin; Mice; Oxidative Stress; Signal Transduct | 2018 |
Melatonin attenuates renal fibrosis in diabetic mice by activating the AMPK/PGC1α signaling pathway and rescuing mitochondrial function.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Diabetes Mellitus, Experimental; Down-Regulation; | 2019 |
Melatonin therapy protects against renal injury before and after release of bilateral ureteral obstruction in rats.
Topics: Animals; Antioxidants; Aquaporins; Glomerular Filtration Rate; Kidney Diseases; Male; Melatonin; Pro | 2019 |
Treatment with melatonin and selenium attenuates docetaxel-induced apoptosis and oxidative injury in kidney and testes of mice.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Disease Models, Animal; Docetaxel; Drug The | 2019 |
Impact of light/dark cycle patterns on oxidative stress in an adriamycin-induced nephropathy model in rats.
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Doxorubicin; Hyperlipidemias; Kidney D | 2014 |
Serum levels of interleukin-1 beta, interleukin-6 and melatonin over summer and winter in kidney deficiency syndrome in Bizheng rats.
Topics: Animals; Arthritis, Experimental; Collagen; Interleukin-1beta; Interleukin-6; Kidney Diseases; Melat | 2014 |
Effects of melatonin on the serum levels of pro-inflammatory cytokines and tissue injury after renal ischemia reperfusion in rats.
Topics: Animals; Antioxidants; Biological Factors; Inflammation; Interleukin-6; Kidney; Kidney Diseases; Lip | 2015 |
Role of Exogenous Melatonin on Cell Proliferation and Oxidant/Antioxidant System in Aluminum-Induced Renal Toxicity.
Topics: Alum Compounds; Animals; Antioxidants; Cell Proliferation; Kidney; Kidney Diseases; Kidney Function | 2015 |
Effects of Lycopene Alone or Combined with Melatonin on Methotrexate-Induced Nephrotoxicity in Rats.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Carotenoids; Drug | 2015 |
Melatonin attenuates hypertension-induced renal injury partially through inhibiting oxidative stress in rats.
Topics: Animals; Blood Pressure; Creatinine; Edema; Gene Expression Regulation; Heme Oxygenase-1; Hypertensi | 2016 |
Melatonin can attenuate ciprofloxacin induced nephrotoxicity: Involvement of nitric oxide and TNF-α.
Topics: Animals; Ciprofloxacin; Creatinine; Glutathione; Kidney; Kidney Diseases; Kidney Function Tests; Lip | 2016 |
Role for NF-κB inflammatory signalling pathway in tenofovir disoproxil fumarate (TDF) induced renal damage in rats.
Topics: Animals; Anti-HIV Agents; Antioxidants; Blotting, Western; Cyclooxygenase 2; Enzyme-Linked Immunosor | 2017 |
Effects of melatonin and vitamin C on cigarette smoke-induced damage in the kidney.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Female; Glutathione; Kidney Diseases; Malondialdehyd | 2007 |
Effect of melatonin, curcumin, quercetin, and resveratrol on acute ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative damage in rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Catalase; Curcumin; Disease Models, Animal; Ferric Compo | 2008 |
Protective effect of melatonin against formaldehyde-induced kidney damage in rats.
Topics: Analysis of Variance; Animals; Formaldehyde; Glutathione Peroxidase; Kidney Diseases; Least-Squares | 2007 |
Melatonin prevents acetaminophen-induced nephrotoxicity in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Kidney; Kidney Diseases; Male; Melatonin; Rats; Ra | 2009 |
Melatonin, a potent regulator of hemeoxygenase-1, reduces cardiopulmonary bypass-induced renal damage in rats.
Topics: Animals; Cardiopulmonary Bypass; Catalase; Disease Models, Animal; Gene Expression; Heme Oxygenase-1 | 2009 |
Melatonin attenuates unilateral ureteral obstruction-induced renal injury by reducing oxidative stress, iNOS, MAPK, and NF-kB expression.
Topics: Animals; Cell Movement; Fibrosis; Glutathione; Immunohistochemistry; Kidney Diseases; Leukocytes; Li | 2009 |
Impairment of endogenous melatonin rhythm is related to the degree of chronic kidney disease (CREAM study).
Topics: Aged; Body Temperature; Chronic Disease; Circadian Rhythm; Female; Humans; Hydrocortisone; Kidney; K | 2010 |
Comparison of the efficacy of melatonin and 1400W on renal ischemia/reperfusion injury: a role for inhibiting iNOS.
Topics: Amidines; Animals; Antioxidants; Benzylamines; Disease Models, Animal; Enzyme Inhibitors; Kidney; Ki | 2009 |
Liquorice plant extract reduces ochratoxin A-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Drug Therapy, Combination; Glycyrrhiza; Kidney Diseases; Kidney Function Test | 2011 |
Protective effects of melatonin and S-methylisothiourea on mechlorethamine induced nephrotoxicity.
Topics: Animals; Chemical Warfare Agents; Disease Models, Animal; Inflammation; Isothiuronium; Kidney Diseas | 2012 |
Melatonin attenuates gentamicin-induced nephrotoxicity and oxidative stress in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Blood Urea Nitrogen; Creatinine; Gentamicin | 2012 |
Melatonin with 1,25-dihydroxyvitamin D3 protects against apoptotic ischemia-reperfusion injury in the rat kidney.
Topics: Animals; Antioxidants; Apoptosis; Calcitriol; Caspase 3; Kidney; Kidney Diseases; Kidney Tubules; Ma | 2012 |
Melatonin supplementation in rat ameliorates ovariectomy-induced oxidative stress.
Topics: Animals; Ascorbic Acid; Catalase; Corticosterone; Estrogen Replacement Therapy; Estrogens; Female; G | 2013 |
Effect of melatonin on hyperlipidemic nephropathy under constant light exposure.
Topics: Animals; Cholesterol; Creatinine; Doxorubicin; Hyperlipidemias; Kidney; Kidney Diseases; Light; Lipo | 2002 |
Melatonin effect on renal oxidative stress under constant light exposure.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Doxorubicin; Humans; Kidney; Kidney Diseases; Li | 2003 |
Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Immunohistochemi | 2003 |
Prevention of shock wave-induced renal oxidative stress by melatonin: an experimental study.
Topics: Animals; Free Radical Scavengers; Hemorrhage; Kidney; Kidney Diseases; Leukocyte Count; Lithotripsy; | 2004 |
Melatonin decreases apoptosis and expression of apoptosis-associated proteins in acute puromycin aminonucleoside nephrosis.
Topics: Animals; Apoptosis; In Situ Nick-End Labeling; Kidney Diseases; Male; Melatonin; Oxidative Stress; P | 2004 |
Melatonin protects against lead-induced hepatic and renal toxicity in male rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Glutathione; Histocytochemistry; Karyometry; Kidney | 2005 |
Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity.
Topics: Amrinone; Animals; Anti-Bacterial Agents; Antioxidants; Female; Free Radicals; Ginkgo biloba; Glutat | 2005 |
Melatonin protects against pressure ulcer-induced oxidative injury of the skin and remote organs in rats.
Topics: Administration, Topical; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitr | 2006 |
Effects of melatonin on suppression of renal scarring in experimental model of pyelonephritis.
Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cicatrix; Disease Models, Animal; Drug Therapy, Combina | 2006 |
Contrast-induced nephropathy: preventive and protective effects of melatonin.
Topics: Animals; Antioxidants; Contrast Media; Kidney Diseases; Male; Melatonin; Rats; Rats, Sprague-Dawley | 2006 |
The effect of melatonin on 7,12-dimethyl-benz[a]anthracene injury in comparison with vitamin E + selenium in mouse kidneys.
Topics: Animals; Antioxidants; Benz(a)Anthracenes; Catalase; Female; Glutathione Peroxidase; Kidney; Kidney | 2006 |
Polymorphonuclear leucocyte priming in long intermittent nocturnal haemodialysis patients--is melatonin a player?
Topics: Chronic Disease; Circadian Rhythm; Female; Humans; Kidney Diseases; Male; Melatonin; Middle Aged; Ne | 2006 |
Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in rats: effects of melatonin treatment.
Topics: Aging; Animals; Antioxidants; Endotoxemia; Enzyme Induction; Injections; Kidney Diseases; Lipid Pero | 2006 |
Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury.
Topics: 5-Hydroxytryptophan; Animals; Hyperglycemia; Kidney Cortex; Kidney Diseases; Kidney Tubules; Male; M | 2007 |
Protective effects of chronic melatonin treatment against renal ischemia/reperfusion injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Kidney Diseases; Lipid Peroxidation; Male; M | 2007 |
[Age dependent changes in the serum melatonin concentrations in healthy human subjects and in patients with endocrine and hepatic disorders and renal failure (author's transl)].
Topics: Adolescent; Adult; Age Factors; Aged; Endocrine System Diseases; Female; Humans; Kidney Diseases; Li | 1981 |
Hyperlipidemic nephropathy induced by adriamycin: effect of melatonin administration.
Topics: Animals; Antioxidants; Catalase; Creatinine; Doxorubicin; Free Radical Scavengers; Free Radicals; Gl | 1997 |
Protective role of melatonin and retinol palmitate in oxidative stress and hyperlipidemic nephropathy induced by adriamycin in rats.
Topics: Animals; Diterpenes; Doxorubicin; Glutathione; Hyperlipidemias; Kidney; Kidney Diseases; Lipid Metab | 1998 |
Melatonin: an antioxidant protects against cyclosporine-induced nephrotoxicity.
Topics: Animals; Antioxidants; Calcinosis; Creatinine; Cyclosporine; Kidney Diseases; Lithium; Male; Malondi | 1999 |
Renal toxicity of the carcinogen delta-aminolevulinic acid: antioxidant effects of melatonin.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aminolevulinic Acid; Animals; Antioxidants; Carcinogens; Deoxyguanosine | 2000 |
Melatonin, a pineal secretory product with antioxidant properties, protects against cisplatin-induced nephrotoxicity in rats.
Topics: Animals; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Cisplatin; Creatinine; Free Radic | 2001 |
Protective effect of melatonin on renal injury of rats induced by bile duct ligation.
Topics: Animals; Antioxidants; Bile Ducts; Kidney Diseases; Ligation; Male; Melatonin; Rats; Rats, Sprague-D | 2001 |
Melatonin prevents cyclosporine-induced nephrotoxicity in isolated and perfused rat kidney.
Topics: Animals; Antioxidants; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; K | 2002 |