melatonin has been researched along with Ischemic Stroke in 12 studies
Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We explored the potential efficacy of melatonin in the treatment of patients with acute ischemic stroke." | 9.51 | Melatonin supplementation may benefit patients with acute ischemic stroke not eligible for reperfusion therapies: Results of a pilot study. ( Ahmadimoghaddam, D; Khazaie, M; Mazdeh, M; Mehrpooya, M; Rahmani, E, 2022) |
| "Melatonin is a potent neuroprotective agent which has shown therapeutic effects in animal models of brain injury such as stroke." | 8.12 | Photothrombotic Mouse Models for the Study of Melatonin as a Therapeutic Tool After Ischemic Stroke. ( Cambiaghi, M; Cherchi, L; Comai, S, 2022) |
| "Consecutive patients admitted to the Tübingen University Stroke Unit, Tübingen, Germany, with acute ischemic stroke (AIS), who underwent standard care between August 2017 and December 2017, and patients who additionally received prophylactic melatonin (2 mg per day at night) within 24 h of symptom onset between August 2018 and December 2018 were included." | 8.02 | Delirium REduction after administration of melatonin in acute ischemic stroke (DREAMS): A propensity score-matched analysis. ( Boßelmann, C; Brendel, B; Fleischmann, R; Meisel, A; Mengel, A; Poli, S; Sartor-Pfeiffer, J; Stadler, V; Stefanou, MI; Ziemann, U; Zurloh, J, 2021) |
| "Obesity is a predominant risk factor in ischemic stroke and is commonly comorbid with it." | 6.72 | Ischemic stroke, obesity, and the anti-inflammatory role of melatonin. ( Govitrapong, P; Tocharus, C; Tocharus, J; Yawoot, N, 2021) |
| "Melatonin is a promising neuroprotective agent that can regulate microglial polarization in central nervous system (CNS) diseases." | 5.91 | Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice. ( He, T; Li, D; Liu, J; Wang, D; Wang, Q; Yuan, Y; Zhang, S; Zhang, Y; Zhao, H, 2023) |
| "Melatonin treatment significantly inhibited the above changes through modulating α7nAChR." | 5.72 | Modulation of α7nAchR by Melatonin Alleviates Ischemia and Reperfusion-Compromised Integrity of Blood-Brain Barrier Through Inhibiting HMGB1-Mediated Microglia Activation and CRTC1-Mediated Neuronal Loss. ( Chen, S; Hu, X; Jin, X; Li, F; Li, H; Li, Y; Liu, W; Sun, Y; Zhang, J; Zhang, X; Zhao, X; Zheng, GQ, 2022) |
| "We explored the potential efficacy of melatonin in the treatment of patients with acute ischemic stroke." | 5.51 | Melatonin supplementation may benefit patients with acute ischemic stroke not eligible for reperfusion therapies: Results of a pilot study. ( Ahmadimoghaddam, D; Khazaie, M; Mazdeh, M; Mehrpooya, M; Rahmani, E, 2022) |
| "Melatonin is a potent neuroprotective agent which has shown therapeutic effects in animal models of brain injury such as stroke." | 4.12 | Photothrombotic Mouse Models for the Study of Melatonin as a Therapeutic Tool After Ischemic Stroke. ( Cambiaghi, M; Cherchi, L; Comai, S, 2022) |
| "Consecutive patients admitted to the Tübingen University Stroke Unit, Tübingen, Germany, with acute ischemic stroke (AIS), who underwent standard care between August 2017 and December 2017, and patients who additionally received prophylactic melatonin (2 mg per day at night) within 24 h of symptom onset between August 2018 and December 2018 were included." | 4.02 | Delirium REduction after administration of melatonin in acute ischemic stroke (DREAMS): A propensity score-matched analysis. ( Boßelmann, C; Brendel, B; Fleischmann, R; Meisel, A; Mengel, A; Poli, S; Sartor-Pfeiffer, J; Stadler, V; Stefanou, MI; Ziemann, U; Zurloh, J, 2021) |
| "Obesity is a predominant risk factor in ischemic stroke and is commonly comorbid with it." | 2.72 | Ischemic stroke, obesity, and the anti-inflammatory role of melatonin. ( Govitrapong, P; Tocharus, C; Tocharus, J; Yawoot, N, 2021) |
| "Melatonin is a promising neuroprotective agent that can regulate microglial polarization in central nervous system (CNS) diseases." | 1.91 | Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice. ( He, T; Li, D; Liu, J; Wang, D; Wang, Q; Yuan, Y; Zhang, S; Zhang, Y; Zhao, H, 2023) |
| "differed significantly." | 1.72 | Diurnal variation of clock genes expression and other sleep-wake rhythm biomarkers among acute ischemic stroke patients. ( Arstikyte, J; Bassetti, CL; Daiva, R; Kupcinskas, J; Pajediene, E; Paulekas, E; Petrikonis, K; Salteniene, V; Skieceviciene, J, 2022) |
| "Melatonin treatment significantly inhibited the above changes through modulating α7nAChR." | 1.72 | Modulation of α7nAchR by Melatonin Alleviates Ischemia and Reperfusion-Compromised Integrity of Blood-Brain Barrier Through Inhibiting HMGB1-Mediated Microglia Activation and CRTC1-Mediated Neuronal Loss. ( Chen, S; Hu, X; Jin, X; Li, F; Li, H; Li, Y; Liu, W; Sun, Y; Zhang, J; Zhang, X; Zhao, X; Zheng, GQ, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 12 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pajediene, E | 1 |
| Paulekas, E | 1 |
| Salteniene, V | 1 |
| Skieceviciene, J | 1 |
| Arstikyte, J | 1 |
| Petrikonis, K | 1 |
| Kupcinskas, J | 1 |
| Bassetti, CL | 1 |
| Daiva, R | 1 |
| Cambiaghi, M | 1 |
| Cherchi, L | 1 |
| Comai, S | 1 |
| Lu, D | 1 |
| Liu, Y | 2 |
| Huang, H | 1 |
| Hu, M | 1 |
| Li, T | 1 |
| Wang, S | 1 |
| Shen, S | 1 |
| Wu, R | 1 |
| Cai, W | 1 |
| Lu, T | 1 |
| Lu, Z | 1 |
| Mehrpooya, M | 1 |
| Mazdeh, M | 1 |
| Rahmani, E | 1 |
| Khazaie, M | 1 |
| Ahmadimoghaddam, D | 1 |
| Pawluk, H | 1 |
| Kołodziejska, R | 1 |
| Grześk, G | 1 |
| Woźniak, A | 1 |
| Kozakiewicz, M | 1 |
| Kosinska, A | 1 |
| Pawluk, M | 1 |
| Grzechowiak, E | 1 |
| Wojtasik, J | 1 |
| Kozera, G | 1 |
| Lian, Z | 1 |
| Xu, Y | 1 |
| Wang, C | 1 |
| Chen, Y | 1 |
| Yuan, L | 1 |
| Liu, Z | 1 |
| He, P | 1 |
| Cai, Z | 1 |
| Zhao, J | 1 |
| Li, D | 1 |
| He, T | 1 |
| Zhang, Y | 1 |
| Liu, J | 1 |
| Zhao, H | 1 |
| Wang, D | 1 |
| Wang, Q | 1 |
| Yuan, Y | 1 |
| Zhang, S | 1 |
| Kılıç, E | 1 |
| Çağlayan, B | 1 |
| Caglar Beker, M | 1 |
| Zhang, XX | 1 |
| Cai, XY | 1 |
| Zhao, HR | 1 |
| Wang, H | 2 |
| Wang, DP | 1 |
| Zhang, QQ | 1 |
| Fang, Q | 1 |
| Yawoot, N | 1 |
| Govitrapong, P | 1 |
| Tocharus, C | 1 |
| Tocharus, J | 1 |
| Mengel, A | 1 |
| Zurloh, J | 1 |
| Boßelmann, C | 1 |
| Brendel, B | 1 |
| Stadler, V | 1 |
| Sartor-Pfeiffer, J | 1 |
| Meisel, A | 1 |
| Fleischmann, R | 1 |
| Ziemann, U | 1 |
| Poli, S | 1 |
| Stefanou, MI | 1 |
| Chen, S | 1 |
| Sun, Y | 1 |
| Li, F | 1 |
| Zhang, X | 1 |
| Hu, X | 1 |
| Zhao, X | 1 |
| Li, Y | 1 |
| Li, H | 1 |
| Zhang, J | 1 |
| Liu, W | 1 |
| Zheng, GQ | 1 |
| Jin, X | 1 |
2 reviews available for melatonin and Ischemic Stroke
| Article | Year |
|---|---|
Physiological and pharmacological roles of melatonin in the pathophysiological components of cellular injury after ischemic stroke
Topics: Animals; Apoptosis; Circadian Rhythm Signaling Peptides and Proteins; Free Radicals; Humans; Ischemi | 2020 |
Ischemic stroke, obesity, and the anti-inflammatory role of melatonin.
Topics: Animals; Anti-Inflammatory Agents; Encephalitis; Humans; Inflammation; Ischemic Stroke; Melatonin; M | 2021 |
1 trial available for melatonin and Ischemic Stroke
| Article | Year |
|---|---|
Melatonin supplementation may benefit patients with acute ischemic stroke not eligible for reperfusion therapies: Results of a pilot study.
Topics: Brain Ischemia; Dietary Supplements; Double-Blind Method; Humans; Ischemic Stroke; Melatonin; Pilot | 2022 |
9 other studies available for melatonin and Ischemic Stroke
| Article | Year |
|---|---|
Diurnal variation of clock genes expression and other sleep-wake rhythm biomarkers among acute ischemic stroke patients.
Topics: Biomarkers; Circadian Rhythm; Humans; Hydrocortisone; Ischemic Stroke; Male; Melatonin; Middle Aged; | 2022 |
Photothrombotic Mouse Models for the Study of Melatonin as a Therapeutic Tool After Ischemic Stroke.
Topics: Animals; Brain Injuries; Brain Ischemia; Disease Models, Animal; Humans; Ischemic Stroke; Melatonin; | 2022 |
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Endothelial Cells; Ischemic Stroke; Melatonin; | 2023 |
Increased Oxidative Stress Markers in Acute Ischemic Stroke Patients Treated with Thrombolytics.
Topics: Antioxidants; Fibrinolytic Agents; Humans; Ischemic Stroke; Melatonin; Oxidation-Reduction; Oxidativ | 2022 |
Gut microbiota-derived melatonin from Puerariae Lobatae Radix-resistant starch supplementation attenuates ischemic stroke injury via a positive microbial co-occurrence pattern.
Topics: Animals; Central Nervous System Depressants; Dysbiosis; Gastrointestinal Microbiome; Ischemic Stroke | 2023 |
Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice.
Topics: Animals; Brain Injuries; Brain Ischemia; Infarction, Middle Cerebral Artery; Ischemic Stroke; Melato | 2023 |
Circadian rhythms of melatonin, cortisol, and clock gene expression in the hyperacute phase of wake-up stroke: study design and measurement.
Topics: Circadian Rhythm; Gene Expression; Humans; Hydrocortisone; Ischemic Stroke; Melatonin | 2020 |
Delirium REduction after administration of melatonin in acute ischemic stroke (DREAMS): A propensity score-matched analysis.
Topics: Brain Ischemia; Delirium; Humans; Ischemic Stroke; Melatonin; Propensity Score; Prospective Studies; | 2021 |
Modulation of α7nAchR by Melatonin Alleviates Ischemia and Reperfusion-Compromised Integrity of Blood-Brain Barrier Through Inhibiting HMGB1-Mediated Microglia Activation and CRTC1-Mediated Neuronal Loss.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Blood-Brain Barrier; HMGB1 Protein; Ischemia; Isch | 2022 |