Page last updated: 2024-10-19

melatonin and Insulinoma

melatonin has been researched along with Insulinoma in 10 studies

Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
" In this study, how nanomolar melatonin regulates insulin synthesis and secretion in rat insulinoma INS-1E cells was investigated."7.96Nanomolar melatonin influences insulin synthesis and secretion in rat insulinoma INS-1E cells. ( Joo, SS; Jung, EM; Yoo, YM, 2020)
" We investigated whether 2-DG reduced intracellular insulin increased by melatonin via autophagy/EDC3 in insulinoma INS-1E cells."7.83Melatonin-Mediated Intracellular Insulin during 2-Deoxy-d-glucose Treatment Is Reduced through Autophagy and EDC3 Protein in Insulinoma INS-1E Cells. ( Han, TY; Kim, HS; Yoo, YM, 2016)
"In this study, we investigated how melatonin mediates insulin synthesis through endoplasmic reticulum (ER) via HuD expression in rat insulinoma INS-1E cells."7.79Melatonin-mediated insulin synthesis during endoplasmic reticulum stress involves HuD expression in rat insulinoma INS-1E cells. ( Yoo, YM, 2013)
"The objective of the present study was to examine the effects of melatonin on transcripts of isoforms of calcium/calmodulin-dependent protein kinases in rat insulinoma beta-cells INS-1."7.75Transcripts of calcium/calmodulin-dependent kinases are changed after forskolin- or IBMX-induced insulin secretion due to melatonin treatment of rat insulinoma beta-cells (INS-1). ( Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S, 2009)
" Long-term administration of melatonin alone reduced CamkIV transcript levels in INS-1 cells; however, transcript levels of Camk2d remained unchanged."5.40Calcium-signaling components in rat insulinoma β-cells (INS-1) and pancreatic islets are differentially influenced by melatonin. ( Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E, 2014)
" In this study, how nanomolar melatonin regulates insulin synthesis and secretion in rat insulinoma INS-1E cells was investigated."3.96Nanomolar melatonin influences insulin synthesis and secretion in rat insulinoma INS-1E cells. ( Joo, SS; Jung, EM; Yoo, YM, 2020)
" We investigated whether 2-DG reduced intracellular insulin increased by melatonin via autophagy/EDC3 in insulinoma INS-1E cells."3.83Melatonin-Mediated Intracellular Insulin during 2-Deoxy-d-glucose Treatment Is Reduced through Autophagy and EDC3 Protein in Insulinoma INS-1E Cells. ( Han, TY; Kim, HS; Yoo, YM, 2016)
"In this study, we investigated how melatonin mediates insulin synthesis through endoplasmic reticulum (ER) via HuD expression in rat insulinoma INS-1E cells."3.79Melatonin-mediated insulin synthesis during endoplasmic reticulum stress involves HuD expression in rat insulinoma INS-1E cells. ( Yoo, YM, 2013)
"The objective of the present study was to examine the effects of melatonin on transcripts of isoforms of calcium/calmodulin-dependent protein kinases in rat insulinoma beta-cells INS-1."3.75Transcripts of calcium/calmodulin-dependent kinases are changed after forskolin- or IBMX-induced insulin secretion due to melatonin treatment of rat insulinoma beta-cells (INS-1). ( Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S, 2009)
" Long-term administration of melatonin alone reduced CamkIV transcript levels in INS-1 cells; however, transcript levels of Camk2d remained unchanged."1.40Calcium-signaling components in rat insulinoma β-cells (INS-1) and pancreatic islets are differentially influenced by melatonin. ( Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Jung, EM1
Joo, SS1
Yoo, YM3
Bazwinsky-Wutschke, I4
Mühlbauer, E7
Albrecht, E3
Peschke, E7
Kim, HS1
Han, TY1
Wolgast, S3
Musshoff, U1
Csernus, VJ1
Chankiewitz, E1
Peschke, D1
Bach, AG1
Stumpf, I1

Other Studies

10 other studies available for melatonin and Insulinoma

ArticleYear
Nanomolar melatonin influences insulin synthesis and secretion in rat insulinoma INS-1E cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020, Volume: 71, Issue:5

    Topics: Animals; bcl-2-Associated X Protein; Cell Line, Tumor; Insulin; Insulinoma; Mechanistic Target of Ra

2020
Melatonin-mediated insulin synthesis during endoplasmic reticulum stress involves HuD expression in rat insulinoma INS-1E cells.
    Journal of pineal research, 2013, Volume: 55, Issue:2

    Topics: Animals; Cell Line, Tumor; ELAV Proteins; ELAV-Like Protein 4; Endoplasmic Reticulum Stress; Insulin

2013
Calcium-signaling components in rat insulinoma β-cells (INS-1) and pancreatic islets are differentially influenced by melatonin.
    Journal of pineal research, 2014, Volume: 56, Issue:4

    Topics: Animals; Antioxidants; Base Sequence; Calcium Signaling; Cell Line, Tumor; Humans; Insulinoma; Melat

2014
Melatonin-Mediated Intracellular Insulin during 2-Deoxy-d-glucose Treatment Is Reduced through Autophagy and EDC3 Protein in Insulinoma INS-1E Cells.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Autophagy; Deoxyglucose; Endoplasmic Reticulum Chaperone BiP; Insulin; Insulin-Secreting Cells; Insu

2016
Transcripts of calcium/calmodulin-dependent kinases are changed after forskolin- or IBMX-induced insulin secretion due to melatonin treatment of rat insulinoma beta-cells (INS-1).
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2009, Volume: 41, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Li

2009
Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets.
    Journal of pineal research, 2012, Volume: 52, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line, Tumor; Cyclic AMP; Histocytochemistry; Insulin; Ins

2012
Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).
    Journal of pineal research, 2012, Volume: 53, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line,

2012
Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.
    Journal of pineal research, 2002, Volume: 33, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Biological Transport; Colforsin; Cyclic AMP

2002
Melatonin stimulates inositol-1,4,5-trisphosphate and Ca2+ release from INS1 insulinoma cells.
    Journal of pineal research, 2005, Volume: 39, Issue:3

    Topics: Animals; Calcium; Carbachol; Cell Line, Tumor; Electrophoresis, Agar Gel; Inositol 1,4,5-Trisphospha

2005
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleot

2008