melatonin has been researched along with Infant, Newborn, Diseases in 9 studies
Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These studies demonstrate a significant neuroprotective efficacy of melatonin in term neonatal models of hypoxia-ischaemia, and suggest melatonin is a strong candidate for translation to clinical trials in babies with moderate-severe NE." | 9.22 | Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia. ( Golay, X; Han, HJ; Meehan, C; Miller, SL; Pang, R; Robertson, NJ, 2022) |
| "The objective of this study is to evaluate the therapeutic efficacy of melatonin as an adjuvant therapy in treating neonatal sepsis." | 9.20 | Use of melatonin as an adjuvant therapy in neonatal sepsis. ( Attia, GF; El Frargy, M; El-Sharkawy, HM, 2015) |
| "These studies demonstrate a significant neuroprotective efficacy of melatonin in term neonatal models of hypoxia-ischaemia, and suggest melatonin is a strong candidate for translation to clinical trials in babies with moderate-severe NE." | 5.22 | Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia. ( Golay, X; Han, HJ; Meehan, C; Miller, SL; Pang, R; Robertson, NJ, 2022) |
| "The objective of this study is to evaluate the therapeutic efficacy of melatonin as an adjuvant therapy in treating neonatal sepsis." | 5.20 | Use of melatonin as an adjuvant therapy in neonatal sepsis. ( Attia, GF; El Frargy, M; El-Sharkawy, HM, 2015) |
| " Melatonin, a biologically active substance, acts as a pleiotropic hormone essential for pregnancy and fetal development." | 5.01 | Perinatal Use of Melatonin for Offspring Health: Focus on Cardiovascular and Neurological Diseases. ( Hsu, CN; Huang, LT; Tain, YL, 2019) |
| "Neonatal encephalopathy is a leading cause of morbidity and mortality worldwide." | 2.72 | Melatonin for Neonatal Encephalopathy: From Bench to Bedside. ( Advic-Belltheus, A; Fullen, DJ; Golay, X; Meehan, C; Pang, R; Robertson, NJ, 2021) |
| "Melatonin has been reported recently to reduce oxidative stress in neonates with sepsis, asphyxia, and respiratory distress." | 2.71 | Melatonin reduces oxidative stress in surgical neonates. ( Antonuccio, P; Barberi, I; Basile, M; Gentile, C; Gitto, E; Impellizzeri, P; Pesce, S; Reiter, RJ; Romeo, C; Trimarchi, G; Zuccarello, B, 2004) |
| "Melatonin was given i." | 1.37 | Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke. ( Baud, O; Biran, V; Charriaut-Marlangue, C; Fau, S; Renolleau, S; Villapol, S, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Pang, R | 2 |
| Han, HJ | 1 |
| Meehan, C | 2 |
| Golay, X | 2 |
| Miller, SL | 1 |
| Robertson, NJ | 2 |
| Hsu, CN | 1 |
| Huang, LT | 1 |
| Tain, YL | 1 |
| Advic-Belltheus, A | 1 |
| Fullen, DJ | 1 |
| Ahmad, QM | 1 |
| Chishti, AL | 1 |
| Waseem, N | 1 |
| Tarocco, A | 1 |
| Caroccia, N | 1 |
| Morciano, G | 1 |
| Wieckowski, MR | 1 |
| Ancora, G | 1 |
| Garani, G | 1 |
| Pinton, P | 1 |
| Gitto, E | 2 |
| Marseglia, L | 1 |
| Manti, S | 1 |
| D'Angelo, G | 1 |
| Barberi, I | 2 |
| Salpietro, C | 1 |
| Reiter, RJ | 2 |
| El Frargy, M | 1 |
| El-Sharkawy, HM | 1 |
| Attia, GF | 1 |
| Villapol, S | 1 |
| Fau, S | 1 |
| Renolleau, S | 1 |
| Biran, V | 1 |
| Charriaut-Marlangue, C | 1 |
| Baud, O | 1 |
| Romeo, C | 1 |
| Impellizzeri, P | 1 |
| Pesce, S | 1 |
| Basile, M | 1 |
| Antonuccio, P | 1 |
| Trimarchi, G | 1 |
| Gentile, C | 1 |
| Zuccarello, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Melatonin for Neuroprotection in Term Infants With Hypoxic-ischaemic Encephalopathy[NCT03806816] | 100 participants (Anticipated) | Interventional | 2018-12-13 | Recruiting | |||
| Melatonin for Neuroprotection Following Perinatal Asphyxia[NCT02071160] | Phase 1/Phase 2 | 45 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| Effects of Perioperative Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery[NCT01505465] | 50 participants (Actual) | Interventional | 2012-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Sleep time change from 96 hours before surgery to 72 hours after surgery (NCT01505465)
Timeframe: 96 hours before surgery to 72 hours after surgery
| Intervention | minutes (Mean) |
|---|---|
| Study: Melatonin | 20 |
| Control: Placebo | -55 |
5 reviews available for melatonin and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia.
Topics: Animals; Brain Diseases; Humans; Hypothermia, Induced; Hypoxia; Infant, Newborn; Infant, Newborn, Di | 2022 |
Perinatal Use of Melatonin for Offspring Health: Focus on Cardiovascular and Neurological Diseases.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Female; Fetal Development; Fetal Diseases; Humans; I | 2019 |
Melatonin for Neonatal Encephalopathy: From Bench to Bedside.
Topics: Animals; Brain Diseases; Humans; Hypothermia, Induced; Infant, Newborn; Infant, Newborn, Diseases; M | 2021 |
Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care.
Topics: Autophagy; Blood-Brain Barrier; Cell Death; Female; Free Radical Scavengers; Humans; Infant, Newborn | 2019 |
Protective role of melatonin in neonatal diseases.
Topics: Antioxidants; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Melat | 2013 |
3 trials available for melatonin and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Role of melatonin in management of hypoxic ischaemic encephalopathy in newborns: A randomized control trial.
Topics: Birth Weight; Female; Gestational Age; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, New | 2018 |
Use of melatonin as an adjuvant therapy in neonatal sepsis.
Topics: Anti-Bacterial Agents; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Female; Humans; Inf | 2015 |
Melatonin reduces oxidative stress in surgical neonates.
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Interleukin-6; Interleukin-8; Male; Mela | 2004 |
Melatonin reduces oxidative stress in surgical neonates.
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Interleukin-6; Interleukin-8; Male; Mela | 2004 |
Melatonin reduces oxidative stress in surgical neonates.
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Interleukin-6; Interleukin-8; Male; Mela | 2004 |
Melatonin reduces oxidative stress in surgical neonates.
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Interleukin-6; Interleukin-8; Male; Mela | 2004 |
1 other study available for melatonin and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke.
Topics: Animals; Brain Infarction; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Infant, Newborn; | 2011 |