melatonin has been researched along with Inadequate Sleep in 221 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Studies suggest that melatonin may prevent delirium, a condition of acute brain dysfunction occurring in 20%-30% of hospitalized older adults that is associated with increased morbidity and mortality." | 9.27 | Melatonin and Sleep in Preventing Hospitalized Delirium: A Randomized Clinical Trial. ( Garcia, S; Jaiswal, SJ; Kang, DY; Loeks, M; Lu, CY; McCarthy, TJ; Owens, RL; Song, J; van Niekerk, CJ; Wineinger, NE, 2018) |
| " We reviewed the literature on the role of melatonin and ramelteon in the prevention of sleep disturbances and delirium in intensive care units and analysed the methods of melatonin therapy in an ICU setting." | 9.05 | The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review. ( Cubała, WJ; Lewandowska, K; Małkiewicz, MA; Mędrzycka-Dąbrowska, WA; Siemiński, M; Winklewski, PJ, 2020) |
| " Our previous studies found that melatonin exerts an improvement effect in sleep deprivation (SD)- induced corticosterone overproduction and colitis." | 8.02 | Melatonin Ameliorates Corticosterone-Mediated Oxidative Stress-Induced Colitis in Sleep-Deprived Mice Involving Gut Microbiota. ( Cao, J; Chen, Y; Dong, Y; Gao, T; Wang, Z, 2021) |
| "To determine adiponectin expression in colonic tissue of murine colitis and systemic cytokine expression after melatonin treatments and sleep deprivation." | 7.83 | Melatonin modulates adiponectin expression on murine colitis with sleep deprivation. ( Baik, HW; Choi, JW; Chung, SH; Gye, MC; Jun, JH; Kim, EK; Kim, JB; Kim, SH; Kim, TK; Lim, JY; Park, YS; Sull, JW; Sung, HJ, 2016) |
| " Melatonin is a sleep-related neurohormone, also known to have antioxidant and anti-inflammatory effects in the gastrointestinal tract; however, the effects of melatonin on colitis have been poorly characterized." | 7.81 | Melatonin improves experimental colitis with sleep deprivation. ( Baik, HW; Chung, SH; Kim, DS; Kim, JB; Kim, JH; Kim, TK; Lee, SK; Park, YS, 2015) |
| " Sleep deprivation aggravated, and melatonin attenuated the severity of colitis." | 7.80 | Melatonin attenuates dextran sodium sulfate induced colitis with sleep deprivation: possible mechanism by microarray analysis. ( Ahn, SB; Baik, HW; Chung, SH; Hong, YO; Jo, Y; Jo, YK; Jun, JH; Kim, JH; Kim, OS; Kim, SH; Kim, SS; Park, YS; Shin, JH; Son, BK, 2014) |
| "Although studies have reported the effects of the menstrual cycle on melatonin rhythmicity, none has investigated the effects of menopause on the melatonin rhythm." | 7.73 | Effect of menopause on melatonin and alertness rhythms investigated in constant routine conditions. ( Ferns, GA; Hampton, SM; Skene, DJ; Walters, JF, 2005) |
| "Our objective was to clarify the relationship between the nocturnal melatonin surge and the nocturnal prolactin release in women with normoprolactinemia and mild hyperprolactinemia." | 7.68 | Role of melatonin in nocturnal prolactin secretion in women with normoprolactinemia and mild hyperprolactinemia. ( Okatani, Y; Sagara, Y, 1993) |
| "Obesity has become an epidemic in industrialized and developing countries." | 6.48 | Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression. ( Korkmaz, A; Ma, S; Reiter, RJ; Tan, DX, 2012) |
| "Melatonin has a major role in control of circadian rhythm and sleep regulation and other effects on the immune system, neuroprotection, and oxidant/anti-oxidant activity." | 6.48 | Potential use of melatonin in sleep and delirium in the critically ill. ( Bellapart, J; Boots, R, 2012) |
| "Melatonin is a sleep-related neurohormone and affected by the circadian rhythm and light/dark cycles." | 5.72 | Melatonin protects against body weight gain induced by sleep deprivation in mice. ( Hu, S; Liu, X; Wang, Y; Wei, S; Zhang, R, 2022) |
| "We updated the sleep duration-breast cancer association with 14 years of follow-up of 34,028 women in the SCHS." | 5.39 | Sleep duration, spot urinary 6-sulfatoxymelatonin levels and risk of breast cancer among Chinese women in Singapore. ( Koh, WP; Stanczyk, FZ; Wang, R; Wu, AH; Yu, MC; Yuan, JM, 2013) |
| "Studies suggest that melatonin may prevent delirium, a condition of acute brain dysfunction occurring in 20%-30% of hospitalized older adults that is associated with increased morbidity and mortality." | 5.27 | Melatonin and Sleep in Preventing Hospitalized Delirium: A Randomized Clinical Trial. ( Garcia, S; Jaiswal, SJ; Kang, DY; Loeks, M; Lu, CY; McCarthy, TJ; Owens, RL; Song, J; van Niekerk, CJ; Wineinger, NE, 2018) |
| ", light therapy, sleep deprivation, sleep phase advance and dark therapy, pharmacological in the form of melatonin and psychological consisting of interpersonal and social rhythm therapy or cognitive behavioral therapy for insomnia modified for patients with bipolar disorder." | 5.22 | [Chronotherapy of affective disorders: principles and clinical aspects]. ( Ludwig, VM; Münch, I; Ritter, P; Wirz-Justice, A, 2022) |
| "We conclude that melatonin does not alter the quality of sleep EEG studies in children with epilepsy or suspected epilepsy." | 5.16 | Melatonin does not influence sleep deprivation electroencephalogram recordings in children. ( Gortner, L; Gottschling, S; Gräber, S; Meyer, S; Sander, J; Shamdeen, MG, 2012) |
| "Modafinil is an alerting substance which has been used successfully to treat narcolepsy." | 5.08 | Effect of modafinil on plasma melatonin, cortisol and growth hormone rhythms, rectal temperature and performance in healthy subjects during a 36 h sleep deprivation. ( Bastuji, H; Boissy, I; Brun, J; Chamba, G; Claustrat, B; Girard, P; Khalfallah, Y; Sassolas, G, 1998) |
| " We reviewed the literature on the role of melatonin and ramelteon in the prevention of sleep disturbances and delirium in intensive care units and analysed the methods of melatonin therapy in an ICU setting." | 5.05 | The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review. ( Cubała, WJ; Lewandowska, K; Małkiewicz, MA; Mędrzycka-Dąbrowska, WA; Siemiński, M; Winklewski, PJ, 2020) |
| "Several studies support the relationship between bipolar disorder and circadian cycles, discussing alterations in melatonin, body temperature and cortisol rhythms; disruption of sleep/wake cycle; variations of clock genes; and chronotype." | 4.91 | The bipolarity of light and dark: A review on Bipolar Disorder and circadian cycles. ( Abreu, T; Bragança, M, 2015) |
| " Our previous studies found that melatonin exerts an improvement effect in sleep deprivation (SD)- induced corticosterone overproduction and colitis." | 4.02 | Melatonin Ameliorates Corticosterone-Mediated Oxidative Stress-Induced Colitis in Sleep-Deprived Mice Involving Gut Microbiota. ( Cao, J; Chen, Y; Dong, Y; Gao, T; Wang, Z, 2021) |
| "To determine adiponectin expression in colonic tissue of murine colitis and systemic cytokine expression after melatonin treatments and sleep deprivation." | 3.83 | Melatonin modulates adiponectin expression on murine colitis with sleep deprivation. ( Baik, HW; Choi, JW; Chung, SH; Gye, MC; Jun, JH; Kim, EK; Kim, JB; Kim, SH; Kim, TK; Lim, JY; Park, YS; Sull, JW; Sung, HJ, 2016) |
| " Melatonin is a sleep-related neurohormone, also known to have antioxidant and anti-inflammatory effects in the gastrointestinal tract; however, the effects of melatonin on colitis have been poorly characterized." | 3.81 | Melatonin improves experimental colitis with sleep deprivation. ( Baik, HW; Chung, SH; Kim, DS; Kim, JB; Kim, JH; Kim, TK; Lee, SK; Park, YS, 2015) |
| " Sleep deprivation aggravated, and melatonin attenuated the severity of colitis." | 3.80 | Melatonin attenuates dextran sodium sulfate induced colitis with sleep deprivation: possible mechanism by microarray analysis. ( Ahn, SB; Baik, HW; Chung, SH; Hong, YO; Jo, Y; Jo, YK; Jun, JH; Kim, JH; Kim, OS; Kim, SH; Kim, SS; Park, YS; Shin, JH; Son, BK, 2014) |
| "Although studies have reported the effects of the menstrual cycle on melatonin rhythmicity, none has investigated the effects of menopause on the melatonin rhythm." | 3.73 | Effect of menopause on melatonin and alertness rhythms investigated in constant routine conditions. ( Ferns, GA; Hampton, SM; Skene, DJ; Walters, JF, 2005) |
| "Our objective was to clarify the relationship between the nocturnal melatonin surge and the nocturnal prolactin release in women with normoprolactinemia and mild hyperprolactinemia." | 3.68 | Role of melatonin in nocturnal prolactin secretion in women with normoprolactinemia and mild hyperprolactinemia. ( Okatani, Y; Sagara, Y, 1993) |
| "The nocturnal secretion of plasma melatonin was determined under dim to dark conditions in eight patients with prospectively confirmed premenstrual syndrome and in eight age- and menstrual cycle phase-matched normal control subjects." | 3.68 | Altered waveform of plasma nocturnal melatonin secretion in premenstrual depression. ( Berga, SL; Gillin, JC; Klauber, MR; Kripke, DF; Laughlin, GA; Parry, BL; Yen, SS, 1990) |
| "Eighteen participants meeting insomnia criteria (mean [SD] age 37." | 3.01 | The acute effects of sleep restriction therapy for insomnia on circadian timing and vigilance. ( Bisdounis, L; Espie, CA; Ftouni, S; Kyle, SD; Maurer, LF, 2021) |
| "Several studies report sleep deprivation negatively impacts post-cognitive and physical performance, and other functions." | 3.01 | Melatonin supplementation improves psychomotor and physical performance in collegiate student-athletes following a sleep deprivation night. ( Ammar, A; Chtourou, H; H'Mida, C; Irandoust, K; Mirmoezzi, M; Paryab, N; Taheri, M; Trabelsi, K, 2021) |
| "However, in subjects with tetraplegia the melatonin levels are blunted." | 2.87 | Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation. ( Bertolucci, C; Dahm, A; Frigato, E; Iversen, PO; Kostovski, E; Mowinckel, MC; Sandset, PM; Savikj, M; Skretting, G; Østerud, B, 2018) |
| "Melatonin was used for electroencephalogram (EEG) (n=12), brainstem evoked response audiometry (n=8) and magnetic resonance imaging (MRI) (n=5)." | 2.82 | Melatonin for non-operating room sedation in paediatric population: a systematic review and meta-analysis. ( Ahmed, J; Patel, W; Pullattayil, AK; Razak, A, 2022) |
| "Sleep deprivation is common in critically ill patients in the intensive care unit (ICU)." | 2.80 | Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation? ( Huang, HW; Jiang, L; Lin, ZT; Shen, L; Xi, XM; Zhang, GB; Zheng, BL, 2015) |
| "Sleep deprivation is common in critically ill patients in intensive care units (ICU)." | 2.79 | Impact of oral melatonin on critically ill adult patients with ICU sleep deprivation: study protocol for a randomized controlled trial. ( Cheng, J; Huang, H; Jiang, L; Shen, L; Xi, X; Zhang, G; Zhu, B, 2014) |
| "Nightmares and insomnia in PTSD are hallmark symptoms, yet poorly understood in comparison to the advances toward a biological framework for the disorder." | 2.78 | Sympathetic activity and hypothalamo-pituitary-adrenal axis activity during sleep in post-traumatic stress disorder: a study assessing polysomnography with simultaneous blood sampling. ( Arends, J; Cluitmans, PJ; Kahn, RS; van Liempt, S; Vermetten, E; Westenberg, HG, 2013) |
| "Melatonin offset was delayed and duration was longer in the symptomatic LL vs." | 2.73 | Late, but not early, wake therapy reduces morning plasma melatonin: relationship to mood in Premenstrual Dysphoric Disorder. ( Elliott, JA; Hauger, RL; López, AM; Martínez, LF; Meliska, CJ; Parry, BL; Sorenson, DL, 2008) |
| "It was concluded that, during sleep deprivation with moderate-intensity exercise, creatine supplementation only affects performance of complex central executive tasks." | 2.73 | Creatine supplementation, sleep deprivation, cortisol, melatonin and behavior. ( Corbett, J; Dicks, M; Hall, B; Harris, RC; Hodgson, C; Howard, AN; Langridge, G; McMorris, T, 2007) |
| "Melatonin treatment is of interest in remitted patients with mood disorder to prevent relapses or recurrences, if a complaint of insomnia, poor sleep quality or phase delay syndrome is associated." | 2.72 | Biological rhythms and chronotherapeutics in depression. ( Geoffroy, PA; Palagini, L, 2021) |
| "During sleep deprivation, mental tasks (Stroop color-word conflict test: CWT) were performed for 15 min each hour." | 2.72 | Exposure to bright light modifies HRV responses to mental tasks during nocturnal sleep deprivation. ( Aoki, K; Iwanaga, K; Katsuura, T; Shimomura, Y; Yokoi, M, 2006) |
| "These findings indicate that sleep deprivation has highly reproducible, but independent, effects on brain mechanisms controlling subjective and objective alertness." | 2.71 | Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelated. ( Berardi, AM; Colecchia, EF; Kosslyn, SM; Leproult, R; Stickgold, R; Van Cauter, E, 2003) |
| "Six patients improved after sleep deprivation (> or =50% reduction on SIGH-SAD(22) score)." | 2.71 | Melatonin treatment of winter depression following total sleep deprivation: waking EEG and mood correlates. ( Danilenko, KV; Putilov, AA, 2005) |
| "Late Wake Treatment (LWT), sleep deprivation for the last half of one night, is associated with rapid mood improvement which has been sustained by light treatment." | 2.71 | Bright green light treatment of depression for older adults [ISRCTN69400161]. ( Grandner, MA; Knickerbocker, NC; Kripke, DF; Loving, RT, 2005) |
| "In the 17 children who underwent sleep deprivation, 13 (76%) went to sleep and had a successful MRI examination." | 2.70 | The use of melatonin as an alternative to sedation in uncooperative children undergoing an MRI examination. ( Johnson, K; Page, A; Wassemer, E; Whitehouse, W; Williams, H, 2002) |
| "Sleep deprivation is extremely common in the intensive care unit (ICU), and this lack of sleep is associated with low melatonin secretion." | 2.69 | Effect of melatonin on sleep quality of COPD intensive care patients: a pilot study. ( Dagan, Y; Dolev, S; Komptel, B; Shenkman, L; Shilo, L; Smorjik, Y; Weinberg, U, 2000) |
| "Four treatments during a 45." | 2.68 | Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans. ( Badia, P; Hakel, M; Myers, BL; Plenzler, SC; Wright, KP, 1997) |
| "Emerging evidence suggests that sleep deprivation (SD) and circadian rhythm disruption (CRD) may interact and increase the risk for the development of Alzheimer's disease (AD)." | 2.61 | The role of sleep deprivation and circadian rhythm disruption as risk factors of Alzheimer's disease. ( Chang, RC; Dunnett, S; Ho, YS; Wu, H, 2019) |
| "How can sleep deprivation trigger an epileptic seizure? How do circadian and hormonal changes influence sleep pattern and seizure occurrence? Can hormones or sleeping pills help with sleep in epilepsy? In this article we discuss these and many other questions on sleep in epilepsy, with an emphasis on sleep architecture, hormone changes, mechanistic factors, and possible prevention strategies." | 2.58 | Neuroendocrine aspects of improving sleep in epilepsy. ( Chuang, SH; Crepeau, AZ; Hunn, D; Maganti, R; Reddy, DS, 2018) |
| "Melatonin has been reported to improve sleep efficiency and it was found that eating melatonin-rich foods could assist sleep." | 2.55 | Dietary Sources and Bioactivities of Melatonin. ( Gan, RY; Li, HB; Li, S; Li, Y; Meng, X; Xu, DP; Zhou, Y, 2017) |
| "The molecular effects of chronic sleep deprivation and circadian misalignment are currently being explored as potential mechanistic markers of the deleterious health consequences associated with these states." | 2.50 | Out of synch with society: an update on delayed sleep phase disorder. ( Dijk, DJ; Nesbitt, AD, 2014) |
| "Pain is a multidimensional response involving several levels of expression ranging from somatosensory to emotional." | 2.50 | Restless legs syndrome and pain disorders: what's in common? ( Delgado Rodrigues, RN; Goulart, LI; Prieto Peres, MF, 2014) |
| "Obesity has become an epidemic in industrialized and developing countries." | 2.48 | Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression. ( Korkmaz, A; Ma, S; Reiter, RJ; Tan, DX, 2012) |
| "Melatonin has a major role in control of circadian rhythm and sleep regulation and other effects on the immune system, neuroprotection, and oxidant/anti-oxidant activity." | 2.48 | Potential use of melatonin in sleep and delirium in the critically ill. ( Bellapart, J; Boots, R, 2012) |
| "The consequences of chronic sleep deprivation on energy expenditure have not been fully explored." | 2.47 | Chronic sleep deprivation and seasonality: implications for the obesity epidemic. ( Cizza, G; de Jonge, L; Galli, G; Requena, M, 2011) |
| "The maximum efficacy for jet lag avoidance is by pre-flight adaptation, however, this requires time and commitment." | 2.45 | Managing jet lag: Some of the problems and possible new solutions. ( Arendt, J, 2009) |
| "This high cancer frequency is not explained by any of the conventional causes." | 2.45 | Light-mediated perturbations of circadian timing and cancer risk: a mechanistic analysis. ( Erren, TC; Fuentes-Broto, L; Paredes, SD; Reiter, RJ; Tan, DX, 2009) |
| "Pharmacological treatments for sleep deprivation exist in the form of alertness-enhancing agents, caffeine and modafinil." | 2.44 | Prevention and treatment of sleep deprivation among emergency physicians. ( Nelson, D, 2007) |
| "Furthermore, the response to sleep deprivation has important research implications." | 2.37 | Clinical and biological correlates of sleep deprivation in depression. ( Brown, P; Joffe, RT, 1984) |
| "Chronic sleep deprivation (CSD) model was established using the MMPM method." | 1.91 | Melatonin upregulates BMAL1 to attenuate chronic sleep deprivation-related cognitive impairment by alleviating oxidative stress. ( Hu, Y; Yang, G; Yin, J, 2023) |
| "Corticosterone levels were comparable between the two groups, although ACTH levels were elevated significantly in the sleep deprivation group." | 1.91 | Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague-Dawley rats. ( Li, B; Li, J; Liu, S; Peng, X; Shi, J; Zhong, H; Zhou, X, 2023) |
| "Homeostatic response to sleep deprivation was intact in OAI compared to GS; theta EEG power suggested a greater homeostatic response in OAI." | 1.72 | Homeostatic response to sleep deprivation and circadian rhythmicity are intact in older adults with insomnia. ( Buysse, DJ; Hall, MH; Hasler, BP; Krafty, RT; Tracy, EL; Wilckens, K; Zhang, J, 2022) |
| "Venlafaxine + melatonin treatment improves depression-like behaviour, pentobarbital sodium experimental sleep latency, and sleep duration in CUMS +SD rats." | 1.72 | Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. ( Han, YS; Jiang, HX; Li, CY; Li, ZR; Liu, DG; Wang, YH; Xie, S; Zou, MS, 2022) |
| "Melatonin is a sleep-related neurohormone and affected by the circadian rhythm and light/dark cycles." | 1.72 | Melatonin protects against body weight gain induced by sleep deprivation in mice. ( Hu, S; Liu, X; Wang, Y; Wei, S; Zhang, R, 2022) |
| "A novel therapy by total sleep deprivation followed by a combination of morning light therapy and nocturnal melatonin administration was efficient in stopping his free-running sleep-wake pattern both immediately and in the long term." | 1.62 | Sleep deprivation therapy to reset the circadian pacemaker in a non-24-hour sleep-wake disorder: a case report. ( Guichard, K; Micoulaud-Franchi, JA; Philip, P; Taillard, J, 2021) |
| "Previous research demonstrated that sleep deprivation (SD) resulted in intestinal homeostasis disorder in colon." | 1.56 | Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injury. ( Cao, J; Chen, Y; Dong, Y; Gao, T; Wang, Z, 2020) |
| "Our study demonstrated that sleep deprivation resulted in homeostasis disorder of colon." | 1.56 | Melatonin attenuates microbiota dysbiosis of jejunum in short-term sleep deprived mice. ( Cao, J; Chen, Y; Dong, Y; Gao, T; Wang, Z, 2020) |
| "In this study, we tested several sleep deprivation protocols (mechanical shakes and light interruptions) on Drosophila and delineated their influences on Drosophila sleep." | 1.56 | Screening of sleep assisting drug candidates with a Drosophila model. ( Ma, WW; Peng, IF; Wang, YY, 2020) |
| "Methods for sleep induction (sleep deprivation, melatonin, and combined sleep deprivation/melatonin) were compared." | 1.51 | Sleep deprivation and melatonin for inducing sleep in paediatric electroencephalography: a prospective multicentre service evaluation. ( Alix, JJP; Catania, S; Kandler, RH; Pang, C; Stavroulakis, T, 2019) |
| "Intestinal diseases caused by sleep deprivation (SD) are severe public health threats worldwide." | 1.51 | Role of melatonin in sleep deprivation-induced intestinal barrier dysfunction in mice. ( Cao, J; Chen, Y; Dong, Y; Gao, T; Lin, R; Wang, X; Wang, Z; Yu, Z, 2019) |
| "Melatonin post-treatment of RSD rats also decreased cleavage of caspase-3 and increased reduced glutathione content in LC." | 1.51 | Neuroprotective effect of exogenous melatonin on the noradrenergic neurons of adult male rats' locus coeruleus nucleus following REM sleep deprivation. ( Aliaghaei, A; Amini, M; Danyali, S; Jameie, SB; Khodagholi, F; Mesgar, S; Raoofi, A; Sadeghi, Y; Sorraya, M, 2019) |
| "Melatonin was administered to rats via oral gavage (100mg/kg/day) for 4 weeks." | 1.48 | Melatonin prevents memory impairment induced by high-fat diet: Role of oxidative stress. ( Alzoubi, KH; Khabour, OF; Mahafzah, R; Mayyas, FA, 2018) |
| "The present results suggest that sleep fragmentation and any resultant cognitive deficits are likely not confounded by corresponding deficits in circadian rhythms." | 1.46 | Young children with Down syndrome show normal development of circadian rhythms, but poor sleep efficiency: a cross-sectional study across the first 60 months of life. ( Anand, P; Clark, C; Demara, BI; Edgin, JO; Fernandez, F; Nyhuis, CC; Ruby, NF; Spanò, G, 2017) |
| "Subjective sleepiness, melatonin and cortisol were assessed hourly." | 1.46 | Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness. ( Cajochen, C; Gabel, V; Garbazza, C; Kolodyazhniy, V; Maire, M; Reichert, CF; Schlangen, LJM; Schmidt, C; Viola, AU, 2017) |
| "Shift work and sleep deprivation are thought to disrupt the normal light-dark cycle, although the disruption due to shiftwork may be dependent on sleep deprivation." | 1.46 | Sleep duration, nightshift work, and the timing of meals and urinary levels of 8-isoprostane and 6-sulfatoxymelatonin in Japanese women. ( Goto, Y; Ishihara, K; Konishi, K; Nagao, Y; Nagata, C; Tamura, T; Wada, K; Yamamoto, S, 2017) |
| "Interestingly, the incidence of prostate cancer was significantly associated with ALAN (risk ratio = 1." | 1.46 | The association between artificial light at night and prostate cancer in Gwangju City and South Jeolla Province of South Korea. ( Kim, J; Kim, KY; Kim, YJ; Lee, E, 2017) |
| "PSG showed, in addition to high sleep fragmentation, a major decrease in slow-wave sleep (SWS) and an increase in stage R sleep." | 1.46 | Sleep during an Antarctic summer expedition: new light on "polar insomnia". ( Cortoos, A; Mairesse, O; Marcoen, N; Meeusen, R; Neyt, X; Pattyn, N, 2017) |
| "Melatonin, which promotes the metabolism of many reactive oxygen species (ROS), has antioxidant and neuroprotective properties." | 1.43 | Chronic Melatonin Treatment Prevents Memory Impairment Induced by Chronic Sleep Deprivation. ( Alhashimi, FH; Alzoubi, KH; Bani Salama, FM; Khabour, OF; Mayyas, FA; Mhaidat, NM, 2016) |
| "In addition to sleep fragmentation, women undergo a complex set of physiological and environmental changes upon entering the postpartum period, confounding our understanding of effects of postpartum sleep disturbance." | 1.43 | Effects of a single night of postpartum sleep on childless women's daytime functioning. ( Kinsey, SG; McBean, AL; Montgomery-Downs, HE, 2016) |
| "The melatonin-treated REMSD group showed an increased neural precursor in 44% with respect to the REMSD group and in 28% when contrasted with the control group (P < 0." | 1.43 | Prophylactic Role of Oral Melatonin Administration on Neurogenesis in Adult Balb/C Mice during REM Sleep Deprivation. ( Acuña-Castroviejo, D; Chaparro-Huerta, V; Flores-Soto, ME; González-Castañeda, RE; González-Perez, O; Jave-Suarez, LF; López-Armas, G; Rusanova, I; Soto-Rodríguez, S, 2016) |
| "Early-life sleep deprivation (ESD) is a serious condition with severe metabolic sequelae." | 1.42 | Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency. ( Chang, HM; Chen, LY; Liao, WC; Mai, FD; Tiong, C; Tsai, CH; Yang, SF; Youn, SC, 2015) |
| "Melatonin and sleep deprivation were equally efficient in inducing sleep (70% in both groups)." | 1.42 | Occurrence of epileptiform discharges and sleep during EEG recordings in children after melatonin intake versus sleep-deprivation. ( Broström, A; Gustafsson, G; Svanborg, E; Ulander, M; Vrethem, M, 2015) |
| "Acute total sleep deprivation significantly increased cortisol levels (p<0." | 1.42 | Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance. ( Czeisler, CA; Desouza, CA; Drake, AL; Fleshner, M; Frey, DJ; Gronfier, C; Wright, KP, 2015) |
| "Melatonin has strong antioxidant and anti-inflammatory effects that help to restore body's immune and cognitive functions." | 1.42 | The potential role of melatonin on sleep deprivation-induced cognitive impairments: implication of FMRP on cognitive function. ( Choi, YY; Han, SH; Jeon, SJ; Kim, MK; Kwon, KJ; Lee, EJ; Shin, CY, 2015) |
| "Reduced insulin sensitivity was compensated by an increased insulin response to glucose, which may reflect an initial physiological adaptation to maintain normal blood sugar levels during sleep loss." | 1.42 | Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity. ( Depner, CM; Eckel, RH; Higgins, J; Markwald, RR; McHill, AW; Melanson, EL; Perreault, L; Smith, MR; Wright, KP, 2015) |
| "Finally, acute sleep deprivation impaired behavioral performance and the P3a ERP in both groups." | 1.40 | Sleep loss, circadian mismatch, and abnormalities in reorienting of attention in night workers with shift work disorder. ( Drake, CL; Gumenyuk, V; Howard, R; Korzyukov, O; Roth, T, 2014) |
| "Melatonin was administered at 23:00 once a day." | 1.40 | Sleep deprivation aggravates median nerve injury-induced neuropathic pain and enhances microglial activation by suppressing melatonin secretion. ( Chen, CL; Chiang, RP; Huang, CT; Tsai, YJ, 2014) |
| "Body weights were taken on days 7, 14 and 21." | 1.40 | Effects of vitamin E and melatonin on serum testosterone level in sleep deprived Wistar rats. ( Adeyemi, DH; Akindele, OO; Kunle-Alabi, OT; Oghenetega, BO; Raji, Y, 2014) |
| "This study investigated the impact of sleep deprivation on the human circadian system." | 1.39 | Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans. ( Ackermann, K; Kayser, M; Lao, O; Middleton, B; Plomp, R; Revell, VL; Skene, DJ, 2013) |
| "Melatonin (15 mg/kg) was administered to the rats via intraperitoneal injection." | 1.39 | Melatonin ameliorates cognitive impairment induced by sleep deprivation in rats: role of oxidative stress, BDNF and CaMKII. ( Liang, XY; Liu, FE; Zhang, HF; Zhang, HQ; Zhang, L; Zhang, T, 2013) |
| "We updated the sleep duration-breast cancer association with 14 years of follow-up of 34,028 women in the SCHS." | 1.39 | Sleep duration, spot urinary 6-sulfatoxymelatonin levels and risk of breast cancer among Chinese women in Singapore. ( Koh, WP; Stanczyk, FZ; Wang, R; Wu, AH; Yu, MC; Yuan, JM, 2013) |
| "We recently showed that sleep deprivation (SD) exacerbates existing acute lung inflammation, and that melatonin treatment attenuates it via anti-apoptotic and anti-oxidant action." | 1.38 | Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation. ( Baik, HW; Jo, KJ; Kim, BJ; Kim, DH; Kim, JY; Kim, SP; Lee, KH; Lee, SK; Lee, YD, 2012) |
| "Two subject groups underwent a 40 h sleep deprivation protocol under Constant Routine conditions either in Groningen (10 Dutch subjects) or in Berlin (9 German subjects)." | 1.37 | Circadian rhythms in handwriting kinematics and legibility. ( Gordijn, M; Häussler, A; Hermsdörfer, J; Jasper, I, 2011) |
| "Treatment with melatonin (5 and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared to control (sleep deprived)." | 1.37 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice. ( Kumar, A; Kumar, P; Singh, A, 2011) |
| "We showed that rapid-eye-movement (REM) sleep deprivation (RSD) by the platform-over-water method inhibits hippocampal cell proliferation in adrenalectomized rats with low-dose corticosterone clamp." | 1.37 | Inhibition of hippocampal neurogenesis by sleep deprivation is independent of circadian disruption and melatonin suppression. ( Mear, RJ; Mistlberger, RE; Mueller, AD, 2011) |
| "The malondialdehyde (MDA) level was determined for the effect of oxidative stress." | 1.35 | Melatonin attenuates lipopolysaccharide-induced acute lung inflammation in sleep-deprived mice. ( Baik, HW; Baik, TK; Kim, BJ; Kim, JY; Kim, OS; Kwak, YJ; Lee, JH; Lee, KH; Lee, SK; Lee, YD; Song, DY, 2009) |
| "To contrast the effects of total sleep deprivation (TSD) on executive and non-executive function in volunteers homozygous for either the short or long variant of a variable number tandem repeat polymorphism in PERIODS, which is a genetic marker for susceptibility to the negative effect of sleep loss on waking performance." | 1.35 | Early morning executive functioning during sleep deprivation is compromised by a PERIOD3 polymorphism. ( Archer, SN; Dijk, DJ; Groeger, JA; Lo, JC; Viola, AU; von Schantz, M, 2008) |
| "Sleep disorders are interrelated with medical and psychiatric illnesses." | 1.35 | Sleep disorders: causes, effects, and solutions. ( Tibbitts, GM, 2008) |
| "Treatment with melatonin (5 mg/kg and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared with control (sleep-deprived)." | 1.35 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. ( Kumar, A; Singh, A, 2009) |
| "To determine the effects of sleep and sleep deprivation on plasma melatonin concentrations in humans and whether these effects are age-dependent." | 1.34 | Plasma melatonin rhythms in young and older humans during sleep, sleep deprivation, and wake. ( Czeisler, CA; Dijk, DJ; Duffy, JF; Lockley, SW; Zeitzer, JM, 2007) |
| "During the sleep deprivation, the mental task (Stroop color-word conflict test: CWT) was performed each 15 min in one hour." | 1.32 | Effect of bright light on EEG activities and subjective sleepiness to mental task during nocturnal sleep deprivation. ( Aoki, K; Iwanaga, K; Katsuura, T; Shimomura, Y; Shiomura, Y; Yokoi, M, 2003) |
| "Even though sleep deprivation in rodents has been shown to result in death, it was until a few years ago thought that sleep loss results in increased sleepiness and decreased cognitive performance but has little or no adverse effects on human health." | 1.32 | [Impact of sleep debt on physiological rhythms]. ( Leproult, R; Spiegel, K; Van Cauter, E, 2003) |
| "Rapid eye movement sleep deprivation had no impact on circulating L-PGDS levels." | 1.32 | Prostaglandin D synthase (beta-trace) in healthy human sleep. ( Brunner, E; Cohrs, S; Eggert, S; Hajak, G; Jordan, W; Rodenbeck, A; Rüther, E; Tumani, H, 2004) |
| "Melatonin rhythm was hourly assessed simultaneously." | 1.31 | Diurnal preference, sleep habits, circadian sleep propensity and melatonin rhythm in healthy human subjects. ( Kim, K; Kudo, Y; Liu, X; Okawa, M; Shibui, K; Suzuki, H; Tagaya, H; Uchiyama, M, 2000) |
| "These results confirm that sleep deprivation reduces hypothalamic GSH and further indicate that melatonin treatment not only is ineffective in reversing this effect but may actually potentiate it." | 1.31 | Melatonin treatment does not prevent decreases in brain glutathione levels induced by sleep deprivation. ( D'Almeida, V; de Oliveira, AC; Hipólide, DC; Lobo, LL; Nobrega, JN; Tufik, S, 2000) |
| "Melatonin (3 mg) was commenced following chronotherapy and this improved their sleep-wake rhythm." | 1.31 | Therapeutic progress of two sibling cases exhibiting sleep-wake rhythm disorder. ( Maeda, H; Mukai, M; Sakamoto, T; Takaishi, J; Takeuchi, N; Uchimura, N; Waseda, Y, 2000) |
| "on the day after nighttime sleep deprivation." | 1.31 | Effects of one night of sleep deprivation on hormone profiles and performance efficiency. ( Goh, VH; Lee, LK; Lim, CL; Low, EC; Tong, TY, 2001) |
| "The effects of sleep deprivation with or without melatonin treatment on the pineal morphology in rats were studied." | 1.31 | Influence of sleep deprivation coupled with administration of melatonin on the ultrastructure of rat pineal gland. ( Hsu, JC; Lan, CT; Ling, EA, 2001) |
| "Melatonin secretion was assessed by measuring the melatonin metabolite 6-sulphatoxymelatonin by enzyme-linked immunosorbent assay." | 1.30 | Patients in the intensive care unit suffer from severe lack of sleep associated with loss of normal melatonin secretion pattern. ( Balaum, H; Dagan, Y; Dolev, S; Komptel, B; Shenkman, L; Shilo, L; Smorjik, Y; Weinberg, U, 1999) |
| "Ten healthy females underwent 24-h sleep deprivation and entered the circadian sleep propensity assessment setting under the ultra-short sleep-wake schedule." | 1.30 | Correlation between the circadian sleep propensity rhythm and hormonal rhythms under ultra-short sleep-wake cycle. ( Hayakawa, T; Ishibashi, K; Kamei, Y; Kim, K; Kudo, Y; Okawa, M; Shibui, K; Uchiyama, M, 1999) |
| "Early investigations of the effect of sleep deprivation on plasma melatonin reported no major changes." | 1.29 | Overnight human plasma melatonin, cortisol, prolactin, TSH, under conditions of normal sleep, sleep deprivation, and sleep recovery. ( Armstrong, SM; Norman, TR; von Treuer, K, 1996) |
| "However, the three conditions of sleep deprivation could not be distinguished from each other, which suggests that the suppression of TSH by sleep (or the stimulation of TSH by sleep deprivation) is not mediated by melatonin." | 1.27 | Lack of an acute modulatory effect of melatonin on human nocturnal thyrotropin and cortisol secretion. ( Lisansky, EJ; Peake, GT; Qualls, CR; Strassman, RJ, 1988) |
| "Melatonin has been reported to induce or enhance sleep in animals and man." | 1.27 | Endogenous sleep-substances and sleep regulation. ( Borbély, AA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (5.43) | 18.7374 |
| 1990's | 24 (10.86) | 18.2507 |
| 2000's | 67 (30.32) | 29.6817 |
| 2010's | 88 (39.82) | 24.3611 |
| 2020's | 30 (13.57) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, D | 1 |
| Zheng, B | 1 |
| Yu, Z | 2 |
| Lin, S | 1 |
| Tang, Y | 1 |
| Chen, M | 2 |
| Ke, P | 1 |
| Zheng, C | 1 |
| Chen, Y | 8 |
| Wu, X | 1 |
| Primack, C | 1 |
| Gao, T | 5 |
| Wang, Z | 8 |
| Dong, Y | 7 |
| Cao, J | 7 |
| Reiter, AM | 1 |
| Roach, GD | 2 |
| Sargent, C | 1 |
| Ludwig, VM | 1 |
| Münch, I | 1 |
| Wirz-Justice, A | 4 |
| Ritter, P | 1 |
| Tracy, EL | 1 |
| Zhang, J | 1 |
| Wilckens, K | 1 |
| Krafty, RT | 1 |
| Hasler, BP | 1 |
| Hall, MH | 1 |
| Buysse, DJ | 1 |
| Li, ZR | 1 |
| Liu, DG | 1 |
| Xie, S | 1 |
| Wang, YH | 1 |
| Han, YS | 1 |
| Li, CY | 1 |
| Zou, MS | 1 |
| Jiang, HX | 1 |
| Hu, S | 1 |
| Liu, X | 2 |
| Wang, Y | 1 |
| Zhang, R | 1 |
| Wei, S | 1 |
| Hu, Y | 2 |
| Yin, J | 1 |
| Yang, G | 1 |
| Wang, X | 3 |
| Zeng, Y | 1 |
| Zhang, Z | 1 |
| Liang, S | 1 |
| Chang, X | 1 |
| Qin, R | 1 |
| Chen, H | 1 |
| Guo, L | 1 |
| Reis, C | 1 |
| Pilz, LK | 1 |
| Kramer, A | 1 |
| Lopes, LV | 1 |
| Paiva, T | 1 |
| Roenneberg, T | 1 |
| Li, J | 1 |
| Peng, X | 1 |
| Zhong, H | 1 |
| Liu, S | 1 |
| Shi, J | 1 |
| Zhou, X | 1 |
| Li, B | 1 |
| Lewandowska, K | 1 |
| Małkiewicz, MA | 1 |
| Siemiński, M | 1 |
| Cubała, WJ | 1 |
| Winklewski, PJ | 1 |
| Mędrzycka-Dąbrowska, WA | 1 |
| Wallace, PJ | 1 |
| Haber, JJ | 1 |
| Wang, YY | 1 |
| Ma, WW | 1 |
| Peng, IF | 1 |
| McMahon, WR | 2 |
| Ftouni, S | 3 |
| Phillips, AJK | 1 |
| Beatty, C | 1 |
| Lockley, SW | 5 |
| Rajaratnam, SMW | 2 |
| Maruff, P | 2 |
| Drummond, SPA | 2 |
| Anderson, C | 2 |
| Liu, L | 1 |
| Zhang, L | 2 |
| Li, L | 1 |
| Shen, Y | 1 |
| Huang, J | 1 |
| Tang, L | 1 |
| Sholtes, D | 1 |
| Kravitz, HM | 1 |
| Deka, A | 1 |
| Westrick, J | 1 |
| Fogg, LF | 1 |
| Gottlieb, M | 1 |
| Geoffroy, PA | 1 |
| Palagini, L | 1 |
| Maurer, LF | 1 |
| Espie, CA | 1 |
| Bisdounis, L | 1 |
| Kyle, SD | 1 |
| Diep, C | 1 |
| Collet, J | 1 |
| Ahmed, J | 1 |
| Patel, W | 1 |
| Pullattayil, AK | 1 |
| Razak, A | 1 |
| Guichard, K | 1 |
| Micoulaud-Franchi, JA | 1 |
| Philip, P | 2 |
| Taillard, J | 2 |
| Paryab, N | 1 |
| Taheri, M | 1 |
| H'Mida, C | 1 |
| Irandoust, K | 1 |
| Mirmoezzi, M | 1 |
| Trabelsi, K | 1 |
| Ammar, A | 1 |
| Chtourou, H | 1 |
| Meng, X | 1 |
| Li, Y | 1 |
| Li, S | 1 |
| Zhou, Y | 1 |
| Gan, RY | 1 |
| Xu, DP | 1 |
| Li, HB | 1 |
| Fernandez, F | 1 |
| Nyhuis, CC | 1 |
| Anand, P | 1 |
| Demara, BI | 1 |
| Ruby, NF | 2 |
| Spanò, G | 1 |
| Clark, C | 1 |
| Edgin, JO | 1 |
| Gabel, V | 2 |
| Reichert, CF | 2 |
| Maire, M | 2 |
| Schmidt, C | 2 |
| Schlangen, LJM | 1 |
| Kolodyazhniy, V | 2 |
| Garbazza, C | 1 |
| Cajochen, C | 5 |
| Viola, AU | 3 |
| Alzoubi, KH | 2 |
| Mayyas, FA | 2 |
| Mahafzah, R | 1 |
| Khabour, OF | 2 |
| Nagata, C | 1 |
| Tamura, T | 1 |
| Wada, K | 1 |
| Konishi, K | 1 |
| Goto, Y | 1 |
| Nagao, Y | 1 |
| Ishihara, K | 1 |
| Yamamoto, S | 1 |
| Omond, S | 1 |
| Ly, LMT | 1 |
| Beaton, R | 1 |
| Storm, JJ | 1 |
| Hale, MW | 1 |
| Lesku, JA | 1 |
| Polidarová, L | 1 |
| Houdek, P | 1 |
| Sumová, A | 1 |
| Short, MA | 2 |
| Weber, N | 1 |
| Reynolds, C | 1 |
| Coussens, S | 2 |
| Carskadon, MA | 4 |
| Jaiswal, SJ | 1 |
| McCarthy, TJ | 1 |
| Wineinger, NE | 1 |
| Kang, DY | 1 |
| Song, J | 1 |
| Garcia, S | 1 |
| van Niekerk, CJ | 1 |
| Lu, CY | 1 |
| Loeks, M | 1 |
| Owens, RL | 1 |
| Kostovski, E | 1 |
| Frigato, E | 1 |
| Savikj, M | 1 |
| Dahm, A | 1 |
| Sandset, PM | 1 |
| Mowinckel, MC | 1 |
| Skretting, G | 1 |
| Østerud, B | 1 |
| Bertolucci, C | 1 |
| Iversen, PO | 1 |
| Alix, JJP | 1 |
| Kandler, RH | 1 |
| Pang, C | 1 |
| Stavroulakis, T | 1 |
| Catania, S | 1 |
| Zaiwalla, Z | 1 |
| Carlson, LA | 1 |
| Pobocik, KM | 1 |
| Lawrence, MA | 1 |
| Brazeau, DA | 1 |
| Koch, AJ | 1 |
| Reddy, DS | 1 |
| Chuang, SH | 1 |
| Hunn, D | 1 |
| Crepeau, AZ | 1 |
| Maganti, R | 1 |
| Lin, R | 1 |
| Honma, A | 1 |
| Revell, VL | 3 |
| Gunn, PJ | 1 |
| Davies, SK | 1 |
| Middleton, B | 3 |
| Raynaud, FI | 1 |
| Skene, DJ | 4 |
| Wu, H | 1 |
| Dunnett, S | 1 |
| Ho, YS | 1 |
| Chang, RC | 1 |
| Jameie, SB | 1 |
| Mesgar, S | 1 |
| Aliaghaei, A | 1 |
| Raoofi, A | 1 |
| Amini, M | 1 |
| Khodagholi, F | 1 |
| Danyali, S | 1 |
| Sorraya, M | 1 |
| Sadeghi, Y | 1 |
| Lehrer, S | 1 |
| Green, S | 1 |
| Ramanathan, L | 1 |
| Rosenzweig, KE | 1 |
| Zhu, Y | 1 |
| Fu, A | 1 |
| Hoffman, AE | 1 |
| Figueiro, MG | 1 |
| Sharkey, KM | 1 |
| Rea, MS | 2 |
| Shekleton, JA | 1 |
| Rajaratnam, SM | 2 |
| Gooley, JJ | 1 |
| Van Reen, E | 1 |
| Czeisler, CA | 4 |
| Ackermann, K | 2 |
| Plomp, R | 1 |
| Lao, O | 2 |
| Kayser, M | 2 |
| Boyce, P | 1 |
| Hopwood, M | 1 |
| Zhang, HQ | 1 |
| Liang, XY | 1 |
| Zhang, HF | 1 |
| Zhang, T | 1 |
| Liu, FE | 1 |
| Chung, SH | 3 |
| Park, YS | 3 |
| Kim, OS | 2 |
| Kim, JH | 2 |
| Baik, HW | 5 |
| Hong, YO | 1 |
| Kim, SS | 1 |
| Shin, JH | 1 |
| Jun, JH | 2 |
| Jo, Y | 1 |
| Ahn, SB | 1 |
| Jo, YK | 1 |
| Son, BK | 1 |
| Kim, SH | 2 |
| Chen, LY | 1 |
| Tiong, C | 1 |
| Tsai, CH | 1 |
| Liao, WC | 1 |
| Yang, SF | 1 |
| Youn, SC | 1 |
| Mai, FD | 1 |
| Chang, HM | 2 |
| Gumenyuk, V | 2 |
| Howard, R | 2 |
| Roth, T | 3 |
| Korzyukov, O | 1 |
| Drake, CL | 2 |
| Strobel, W | 1 |
| Götz, T | 1 |
| Bachmann, V | 1 |
| Landolt, HP | 1 |
| Chang, YS | 1 |
| Chou, YT | 1 |
| Lee, JH | 2 |
| Lee, PL | 1 |
| Dai, YS | 1 |
| Sun, C | 1 |
| Lin, YT | 1 |
| Wang, LC | 1 |
| Yu, HH | 1 |
| Yang, YH | 1 |
| Chen, CA | 1 |
| Wan, KS | 1 |
| Chiang, BL | 1 |
| Davis, GR | 1 |
| Etheredge, CE | 1 |
| Marcus, L | 1 |
| Bellar, D | 1 |
| Huang, H | 1 |
| Jiang, L | 2 |
| Shen, L | 2 |
| Zhang, G | 1 |
| Zhu, B | 1 |
| Cheng, J | 1 |
| Xi, X | 1 |
| Landis, CA | 1 |
| Huang, CT | 1 |
| Chiang, RP | 1 |
| Chen, CL | 1 |
| Tsai, YJ | 1 |
| Parekh, PJ | 1 |
| Oldfield Iv, EC | 1 |
| Challapallisri, V | 1 |
| Ware, JC | 1 |
| Johnson, DA | 1 |
| Nesbitt, AD | 1 |
| Dijk, DJ | 5 |
| Zeitzer, JM | 2 |
| Fisicaro, RA | 1 |
| Heller, HC | 1 |
| Boivin, DB | 1 |
| Boudreau, P | 1 |
| Goulart, LI | 1 |
| Delgado Rodrigues, RN | 1 |
| Prieto Peres, MF | 1 |
| McHill, AW | 2 |
| Melanson, EL | 2 |
| Higgins, J | 2 |
| Connick, E | 1 |
| Moehlman, TM | 1 |
| Stothard, ER | 1 |
| Wright, KP | 5 |
| Gustafsson, G | 1 |
| Broström, A | 1 |
| Ulander, M | 1 |
| Vrethem, M | 1 |
| Svanborg, E | 1 |
| Belcher, R | 1 |
| Levin, AM | 1 |
| Lee, SK | 3 |
| Kim, JB | 2 |
| Kim, TK | 2 |
| Kim, DS | 1 |
| Drake, AL | 1 |
| Frey, DJ | 1 |
| Fleshner, M | 1 |
| Desouza, CA | 1 |
| Gronfier, C | 2 |
| Huang, HW | 1 |
| Zheng, BL | 1 |
| Lin, ZT | 1 |
| Zhang, GB | 1 |
| Xi, XM | 1 |
| Sletten, TL | 1 |
| Segal, AY | 1 |
| Flynn-Evans, EE | 1 |
| Kwon, KJ | 1 |
| Lee, EJ | 1 |
| Kim, MK | 1 |
| Jeon, SJ | 1 |
| Choi, YY | 1 |
| Shin, CY | 1 |
| Han, SH | 1 |
| Bani Salama, FM | 1 |
| Alhashimi, FH | 1 |
| Mhaidat, NM | 1 |
| Mo, Y | 1 |
| Scheer, CE | 1 |
| Abdallah, GT | 1 |
| Akindele, OO | 1 |
| Kunle-Alabi, OT | 1 |
| Adeyemi, DH | 1 |
| Oghenetega, BO | 1 |
| Raji, Y | 1 |
| Abreu, T | 1 |
| Bragança, M | 1 |
| Smolensky, MH | 2 |
| Sackett-Lundeen, LL | 1 |
| Portaluppi, F | 1 |
| Lech, K | 1 |
| Eckel, RH | 1 |
| Depner, CM | 1 |
| Perreault, L | 1 |
| Markwald, RR | 1 |
| Smith, MR | 1 |
| McBean, AL | 1 |
| Kinsey, SG | 1 |
| Montgomery-Downs, HE | 1 |
| Messerschmidt, K | 1 |
| Muto, V | 1 |
| Jaspar, M | 1 |
| Meyer, C | 1 |
| Kussé, C | 1 |
| Chellappa, SL | 1 |
| Degueldre, C | 1 |
| Balteau, E | 1 |
| Shaffii-Le Bourdiec, A | 1 |
| Luxen, A | 1 |
| Archer, SN | 2 |
| Phillips, C | 1 |
| Collette, F | 1 |
| Vandewalle, G | 1 |
| Maquet, P | 1 |
| López-Armas, G | 1 |
| Flores-Soto, ME | 1 |
| Chaparro-Huerta, V | 1 |
| Jave-Suarez, LF | 1 |
| Soto-Rodríguez, S | 1 |
| Rusanova, I | 1 |
| Acuña-Castroviejo, D | 1 |
| González-Perez, O | 1 |
| González-Castañeda, RE | 1 |
| Kim, EK | 1 |
| Sull, JW | 1 |
| Sung, HJ | 1 |
| Choi, JW | 1 |
| Gye, MC | 1 |
| Lim, JY | 1 |
| Baron, KG | 1 |
| Reid, KJ | 1 |
| Kim, T | 1 |
| Van Horn, L | 1 |
| Attarian, H | 1 |
| Wolfe, L | 1 |
| Siddique, J | 1 |
| Santostasi, G | 1 |
| Zee, PC | 1 |
| Agostini, A | 1 |
| Dorrian, J | 3 |
| Kim, KY | 1 |
| Lee, E | 1 |
| Kim, YJ | 1 |
| Kim, J | 1 |
| Korompeli, A | 1 |
| Muurlink, O | 1 |
| Kavrochorianou, N | 1 |
| Katsoulas, T | 1 |
| Fildissis, G | 1 |
| Baltopoulos, G | 1 |
| Pattyn, N | 1 |
| Mairesse, O | 1 |
| Cortoos, A | 1 |
| Marcoen, N | 1 |
| Neyt, X | 1 |
| Meeusen, R | 1 |
| Touitou, Y | 1 |
| Reinberg, A | 1 |
| Touitou, D | 1 |
| Lee, YD | 2 |
| Kim, JY | 3 |
| Lee, KH | 2 |
| Kwak, YJ | 1 |
| Song, DY | 1 |
| Baik, TK | 1 |
| Kim, BJ | 2 |
| Groeger, JA | 1 |
| Lo, JC | 1 |
| von Schantz, M | 1 |
| Parry, BL | 3 |
| Meliska, CJ | 2 |
| Martínez, LF | 2 |
| López, AM | 2 |
| Sorenson, DL | 1 |
| Hauger, RL | 2 |
| Elliott, JA | 1 |
| Tibbitts, GM | 1 |
| Rogers, NL | 1 |
| Dinges, DF | 1 |
| Arendt, J | 2 |
| Azorin, JM | 1 |
| Kaladjian, A | 1 |
| Vanelle, JM | 1 |
| Birchler-Pedross, A | 1 |
| Schröder, CM | 1 |
| Münch, M | 1 |
| Knoblauch, V | 2 |
| Blatter, K | 1 |
| Schnitzler-Sack, C | 1 |
| Verster, GC | 1 |
| Wu, UI | 1 |
| Lan, CT | 2 |
| Bratzke, D | 1 |
| Rolke, B | 1 |
| Steinborn, MB | 1 |
| Ulrich, R | 1 |
| Jasper, I | 2 |
| Häussler, A | 2 |
| Marquardt, C | 1 |
| Hermsdörfer, J | 2 |
| Kumar, A | 2 |
| Singh, A | 2 |
| Wideman, CH | 1 |
| Murphy, HM | 1 |
| Kálmán, J | 1 |
| Kálmán, S | 1 |
| Reiter, RJ | 2 |
| Tan, DX | 2 |
| Erren, TC | 2 |
| Fuentes-Broto, L | 1 |
| Paredes, SD | 1 |
| Costa, G | 1 |
| Haus, E | 1 |
| Stevens, R | 1 |
| Kamperis, K | 1 |
| Hagstroem, S | 1 |
| Radvanska, E | 1 |
| Rittig, S | 1 |
| Djurhuus, JC | 1 |
| Gordijn, M | 1 |
| Kumar, P | 1 |
| Zhdanova, IV | 1 |
| Masuda, K | 1 |
| Quasarano-Kourkoulis, C | 1 |
| Rosene, DL | 1 |
| Killiany, RJ | 1 |
| Wang, S | 1 |
| Minami, M | 1 |
| Takahashi, H | 1 |
| Sasaki, T | 1 |
| Matsumoto, S | 1 |
| Sakai, K | 1 |
| Inagaki, H | 1 |
| Yamano, Y | 1 |
| Miyake, H | 1 |
| Korkmaz, A | 1 |
| Ma, S | 1 |
| Cizza, G | 2 |
| Requena, M | 1 |
| Galli, G | 1 |
| de Jonge, L | 1 |
| Fritschi, L | 1 |
| Glass, DC | 1 |
| Heyworth, JS | 1 |
| Aronson, K | 1 |
| Girschik, J | 1 |
| Boyle, T | 1 |
| Grundy, A | 1 |
| Mueller, AD | 1 |
| Mear, RJ | 1 |
| Mistlberger, RE | 1 |
| Feng, P | 1 |
| Vurbic, D | 1 |
| Guo, Y | 1 |
| Sander, J | 1 |
| Shamdeen, MG | 1 |
| Gottschling, S | 1 |
| Gortner, L | 1 |
| Gräber, S | 1 |
| Meyer, S | 1 |
| Kim, SP | 1 |
| Kim, DH | 1 |
| Jo, KJ | 1 |
| Bellapart, J | 1 |
| Boots, R | 1 |
| Venkateshiah, SB | 1 |
| Collop, NA | 1 |
| Wu, AH | 1 |
| Stanczyk, FZ | 1 |
| Wang, R | 1 |
| Koh, WP | 1 |
| Yuan, JM | 1 |
| Yu, MC | 1 |
| Peuhkuri, K | 1 |
| Sihvola, N | 1 |
| Korpela, R | 1 |
| Gonnissen, HK | 1 |
| Hursel, R | 1 |
| Rutters, F | 1 |
| Martens, EA | 1 |
| Westerterp-Plantenga, MS | 1 |
| van Liempt, S | 1 |
| Arends, J | 1 |
| Cluitmans, PJ | 1 |
| Westenberg, HG | 1 |
| Kahn, RS | 1 |
| Vermetten, E | 1 |
| Lucassen, EA | 1 |
| Rother, KI | 1 |
| Burgess, HJ | 4 |
| Haus, EL | 1 |
| Leatherwood, WE | 1 |
| Dragoo, JL | 1 |
| Voderholzer, U | 1 |
| Riemann, D | 1 |
| Gann, H | 1 |
| Hornyak, M | 1 |
| Juengling, F | 1 |
| Schumacher, M | 1 |
| Reincke, M | 1 |
| Von Herbay, A | 1 |
| Nishino, S | 1 |
| Mignot, E | 1 |
| Berger, M | 1 |
| Lieb, K | 1 |
| Aeschbach, D | 1 |
| Sher, L | 1 |
| Postolache, TT | 1 |
| Matthews, JR | 1 |
| Jackson, MA | 1 |
| Wehr, TA | 2 |
| Leproult, R | 3 |
| Colecchia, EF | 2 |
| Berardi, AM | 1 |
| Stickgold, R | 1 |
| Kosslyn, SM | 1 |
| Van Cauter, E | 3 |
| Koorengevel, KM | 1 |
| Beersma, DG | 1 |
| den Boer, JA | 1 |
| van den Hoofdakker, RH | 1 |
| Jewett, ME | 1 |
| Lamond, N | 2 |
| Holmes, AL | 2 |
| McCulloch, K | 2 |
| Fletcher, A | 2 |
| Dawson, D | 3 |
| Roach, G | 1 |
| Yokoi, M | 2 |
| Aoki, K | 2 |
| Shimomura, Y | 2 |
| Iwanaga, K | 2 |
| Katsuura, T | 2 |
| Shiomura, Y | 1 |
| Spiegel, K | 2 |
| Lavoie, S | 1 |
| Paquet, J | 1 |
| Selmaoui, B | 1 |
| Rufiange, M | 1 |
| Dumont, M | 2 |
| Nir, I | 1 |
| Kräuchi, K | 1 |
| Graw, P | 1 |
| Wallach, D | 1 |
| Jordan, W | 1 |
| Tumani, H | 1 |
| Cohrs, S | 1 |
| Eggert, S | 1 |
| Rodenbeck, A | 1 |
| Brunner, E | 1 |
| Rüther, E | 1 |
| Hajak, G | 1 |
| Buscemi, N | 1 |
| Vandermeer, B | 1 |
| Pandya, R | 1 |
| Hooton, N | 1 |
| Tjosvold, L | 1 |
| Hartling, L | 1 |
| Baker, G | 1 |
| Vohra, S | 1 |
| Klassen, T | 1 |
| Danilenko, KV | 1 |
| Putilov, AA | 1 |
| Kuriyama, K | 1 |
| Uchiyama, M | 5 |
| Suzuki, H | 3 |
| Tagaya, H | 3 |
| Ozaki, A | 1 |
| Aritake, S | 1 |
| Shibui, K | 5 |
| Xin, T | 1 |
| Lan, L | 1 |
| Kamei, Y | 4 |
| Takahashi, K | 1 |
| Taylor, DJ | 1 |
| Jenni, OG | 1 |
| Acebo, C | 1 |
| Bilski, B | 1 |
| Perz, S | 1 |
| Perz, K | 1 |
| Loving, RT | 1 |
| Kripke, DF | 3 |
| Knickerbocker, NC | 1 |
| Grandner, MA | 1 |
| Walters, JF | 1 |
| Hampton, SM | 1 |
| Ferns, GA | 1 |
| BaHammam, A | 1 |
| Eastman, CI | 1 |
| Maurer, EL | 1 |
| Sorenson, D | 1 |
| Moore, N | 1 |
| Claustrat, B | 2 |
| Coste, O | 1 |
| Bioulac, B | 1 |
| Craig, D | 1 |
| Hart, DJ | 1 |
| Passmore, AP | 1 |
| McMorris, T | 1 |
| Harris, RC | 1 |
| Howard, AN | 1 |
| Langridge, G | 1 |
| Hall, B | 1 |
| Corbett, J | 1 |
| Dicks, M | 1 |
| Hodgson, C | 1 |
| Marie Hansen, A | 1 |
| Helene Garde, A | 1 |
| Hansen, J | 1 |
| Nelson, D | 1 |
| Duffy, JF | 1 |
| Gorfine, T | 1 |
| Zisapel, N | 1 |
| Bailey, B | 1 |
| Drouot, X | 1 |
| Cabello, B | 1 |
| d'Ortho, MP | 1 |
| Brochard, L | 1 |
| Joffe, RT | 1 |
| Brown, P | 1 |
| Akerstedt, T | 2 |
| Gillberg, M | 1 |
| Wetterberg, L | 3 |
| Encel, N | 1 |
| Lushington, K | 1 |
| Okatani, Y | 1 |
| Sagara, Y | 1 |
| von Treuer, K | 1 |
| Norman, TR | 1 |
| Armstrong, SM | 1 |
| Rao, ML | 1 |
| Pelzer, E | 1 |
| Papassotiropoulos, A | 1 |
| Tiemeier, H | 1 |
| Jönck, L | 1 |
| Möller, HJ | 1 |
| Badia, P | 2 |
| Myers, BL | 1 |
| Plenzler, SC | 1 |
| Hakel, M | 1 |
| Weibel, L | 1 |
| Follenius, M | 1 |
| Brandenberger, G | 1 |
| Oren, DA | 1 |
| Giesen, HA | 1 |
| Daurat, A | 1 |
| Aguirre, A | 1 |
| Foret, J | 1 |
| Benoit, O | 1 |
| Lafrance, C | 1 |
| Lespérance, P | 1 |
| Lambert, C | 1 |
| Brun, J | 1 |
| Chamba, G | 1 |
| Khalfallah, Y | 1 |
| Girard, P | 1 |
| Boissy, I | 1 |
| Bastuji, H | 1 |
| Sassolas, G | 1 |
| Shilo, L | 2 |
| Dagan, Y | 2 |
| Smorjik, Y | 2 |
| Weinberg, U | 2 |
| Dolev, S | 2 |
| Komptel, B | 2 |
| Balaum, H | 1 |
| Shenkman, L | 2 |
| Okawa, M | 4 |
| Kim, K | 4 |
| Kudo, Y | 3 |
| Hayakawa, T | 2 |
| Urata, J | 1 |
| Ishibashi, K | 1 |
| Spitzer, RL | 1 |
| Terman, M | 1 |
| Williams, JB | 1 |
| Terman, JS | 1 |
| Malt, UF | 1 |
| Singer, F | 1 |
| Lewy, AJ | 2 |
| D'Almeida, V | 1 |
| Hipólide, DC | 1 |
| Lobo, LL | 1 |
| de Oliveira, AC | 1 |
| Nobrega, JN | 1 |
| Tufik, S | 1 |
| Redwine, L | 1 |
| Gillin, JC | 2 |
| Irwin, M | 1 |
| Lavie, P | 2 |
| Mukai, M | 1 |
| Uchimura, N | 1 |
| Takeuchi, N | 1 |
| Waseda, Y | 1 |
| Takaishi, J | 1 |
| Sakamoto, T | 1 |
| Maeda, H | 1 |
| L'Hermite-Balériaux, M | 1 |
| Luboshitzky, R | 1 |
| Zabari, Z | 1 |
| Shen-Orr, Z | 1 |
| Herer, P | 1 |
| Goh, VH | 1 |
| Tong, TY | 1 |
| Lim, CL | 1 |
| Low, EC | 1 |
| Lee, LK | 1 |
| Stevens, RG | 1 |
| Hsu, JC | 1 |
| Ling, EA | 1 |
| Sparaco, P | 1 |
| Roehrs, T | 1 |
| Wassmer, E | 1 |
| Carter, PF | 1 |
| Quinn, E | 1 |
| McLean, N | 1 |
| Welsh, G | 1 |
| Seri, S | 1 |
| Whitehouse, WP | 1 |
| Frentzel-Beyme, R | 1 |
| Johnson, K | 1 |
| Page, A | 1 |
| Williams, H | 1 |
| Wassemer, E | 1 |
| Whitehouse, W | 1 |
| Fröberg, JE | 1 |
| Friberg, Y | 1 |
| Jimerson, DC | 1 |
| Lynch, HJ | 1 |
| Post, RM | 1 |
| Wurtman, RJ | 1 |
| Bunney, WE | 1 |
| Persengiev, S | 1 |
| Kanchev, L | 1 |
| Vezenkova, G | 1 |
| Strassman, RJ | 4 |
| Qualls, CR | 4 |
| Lisansky, EJ | 4 |
| Peake, GT | 4 |
| Persengiev, SP | 1 |
| Kanchev, LN | 1 |
| Horne, JA | 1 |
| Donlon, J | 1 |
| Berga, SL | 1 |
| Klauber, MR | 1 |
| Laughlin, GA | 1 |
| Yen, SS | 1 |
| Bispink, G | 1 |
| Zimmermann, R | 1 |
| Weise, HC | 1 |
| Leidenberger, F | 1 |
| Peder, M | 1 |
| Porkka-Heiskanen, T | 1 |
| Alila, A | 1 |
| Laakso, ML | 1 |
| Johansson, G | 1 |
| Salín-Pascual, RJ | 1 |
| Ortega-Soto, H | 1 |
| Huerto-Delgadillo, L | 1 |
| Camacho-Arroyo, I | 1 |
| Roldán-Roldán, G | 1 |
| Tamarkin, L | 1 |
| Borbély, AA | 1 |
| Hallonquist, JD | 1 |
| Goldberg, MA | 1 |
| Brandes, JS | 1 |
| Sack, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Stellate Ganglion Block in Patients With Advanced Primary Parkinson's Disease: a Small, Open, Randomized, Controlled Clinical Study[NCT06112392] | 38 participants (Anticipated) | Interventional | 2023-07-28 | Recruiting | |||
| The Safety and Efficacy of Fecal Microbiota Transplantation in Patients With Chronic Insomnia Disorder[NCT05917379] | Phase 1/Phase 2 | 80 participants (Anticipated) | Interventional | 2023-07-01 | Not yet recruiting | ||
| Melatonin and Sleep in Preventing Delirium in the Hospital: A Randomized Placebo-controlled Trial[NCT02597231] | Phase 1/Phase 2 | 94 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| Efficacy of Melatony Versus Sleep Deprivation for EEG Recordings in Sleep: a Randomized Crossed-over Study in Pediatric Patients With Epilepsy[NCT05654415] | 30 participants (Anticipated) | Interventional | 2021-09-01 | Active, not recruiting | |||
| Exogenous Melatonin in Intensive Care Unit Chronodisruption: Randomized Controled Trial[NCT03708341] | Phase 3 | 98 participants (Anticipated) | Interventional | 2018-11-15 | Recruiting | ||
| Bright Light as a Countermeasure for Circadian Desynchrony[NCT01119365] | 300 participants (Anticipated) | Interventional | 2011-07-31 | Recruiting | |||
| Treating Sleep Disruption in Teens With Millisecond Light Exposure During Sleep[NCT01406691] | Phase 4 | 20 participants (Anticipated) | Interventional | 2013-12-31 | Recruiting | ||
| Behavioral Chronotype: Impact on Sleep and Metabolism[NCT03647306] | 200 participants (Anticipated) | Interventional | 2018-02-02 | Active, not recruiting | |||
| Examining the Impact of a 12-week Worksite Exercise Training Intervention on Mental, Metabolic, Physical, Spiritual, and Occupational Well-being Among Acute Care Nurses: A Randomized, Controlled Mixed Methods Pilot Study[NCT05966805] | 20 participants (Anticipated) | Interventional | 2023-09-13 | Recruiting | |||
| Reducing Delirium in the Surgical Intensive Care Unit Through the Use of Eye Masks and Earplugs[NCT02856737] | 0 participants (Actual) | Interventional | 2016-08-31 | Withdrawn (stopped due to inadequate personel) | |||
| Melatonin Use in the Intensive Care Elderly Population[NCT03013790] | Phase 4 | 600 participants (Anticipated) | Interventional | 2016-12-31 | Recruiting | ||
| Effect of Massage Therapy on Fatigue and Sleep Quality in Patients With Heart Failure in Intensive Care Unit[NCT05366673] | 90 participants (Actual) | Interventional | 2021-07-15 | Completed | |||
| Restore Resilience in Critically Ill Children[NCT04695392] | 56 participants (Actual) | Interventional | 2017-09-05 | Completed | |||
| Study on the Use of Broadband Sound to Mitigate Sleep Disruption Due to Aircraft Noise[NCT05774977] | 28 participants (Anticipated) | Interventional | 2023-11-13 | Recruiting | |||
| Impact of Low-dose Dexmedetomidine on Outcomes of Elderly Admitted to ICU After Noncardiac Surgery: a Randomized Controlled Trial[NCT04204798] | 1,410 participants (Anticipated) | Interventional | 2020-08-28 | Recruiting | |||
| Efficiency of Intraoral Appliance in the Treatment of Obstructive Sleep Apnea Syndrome in Obese Class III[NCT03517150] | 60 participants (Anticipated) | Interventional | 2016-05-12 | Active, not recruiting | |||
| Effect of Low-dose Dexmedetomidine on Postoperative Delirium in Patients After Cardiac Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03624595] | 502 participants (Anticipated) | Interventional | 2019-04-16 | Active, not recruiting | |||
| A Pilot Placebo-controlled Randomized Double-blind Trial of Melatonin in Outpatients With COVID-19 Infection[NCT04784754] | Phase 2 | 0 participants (Actual) | Interventional | 2021-04-01 | Withdrawn (stopped due to lack of subject enrollment) | ||
| A Pilot Placebo-controlled Randomized Double-blind Trial of Melatonin in Outpatients With COVID-19 Infection[NCT04474483] | Phase 2 | 8 participants (Actual) | Interventional | 2020-11-06 | Terminated (stopped due to difficult recruitment and complete first visit in person during thne hight of tne pandemic and later not enough subjects) | ||
| The Impact of Ramelteon on Sleep and Delirium in Patients Who Undergo Pulmonary Thromboendarterectomy (PTE) Surgery[NCT02691013] | 120 participants (Actual) | Interventional | 2016-02-29 | Active, not recruiting | |||
| Circadian Health in Patients Admitted to Intensive Care Units and Hospitalization (CHRONOHOSPI)[NCT04113876] | 975 participants (Actual) | Observational [Patient Registry] | 2019-01-01 | Completed | |||
| Neurobiology of Individual Differences in Sleep Duration[NCT00607204] | 119 participants (Actual) | Observational | 2005-10-31 | Completed | |||
| Exploratory Study of Melatonin Induced Sleep Regularization in Severe Brain Injury[NCT02732288] | 1 participants (Actual) | Interventional | 2016-05-31 | Terminated (stopped due to Interrupted by Covid-19) | |||
| Relationship Between Asynchronies and Sleep Disruption in Mechanically Ventilated Patients: a Prospective Cohort Study[NCT05847374] | 50 participants (Actual) | Observational | 2019-01-01 | Completed | |||
| Effect of Sleep Disruption on the Outcome of Weaning From Mechanical Ventilation[NCT02464735] | 44 participants (Actual) | Observational | 2016-01-01 | Completed | |||
| Circadian Integration of Photic and Non-photic Stimuli[NCT00387179] | 48 participants (Anticipated) | Interventional | 2006-10-31 | Recruiting | |||
| Operational Evaluation of a Photic Countermeasure to Improve Alertness, Performance, and Mood During Nightshift Work on a 105-day Simulated Human Exploration Mission to Mars[NCT01169233] | 25 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| AgeWise Project 2: Reducing Stress and Sleep Disturbances in Caregivers of Patients With Progressive Dementia[NCT00178568] | 60 participants (Actual) | Observational | 2003-02-28 | Completed | |||
| A Placebo-controlled, Double -Blind Randomised Trial of Suvorexant in the Management Comorbid Sleep Disorder and Alcohol Dependence[NCT03897062] | Phase 2 | 22 participants (Actual) | Interventional | 2019-08-26 | Terminated (stopped due to Recruitment problems during covid lockdowns resulted in Merck ceasing supply of suvorexant/placebo) | ||
| Can Medical Clowns Prevent the Usage of Sedation During the Performance of EEG in Young Children[NCT05257096] | 100 participants (Anticipated) | Interventional | 2019-05-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Measured twice daily during the ICU stay using the Confusions Assessment Method instrument. (NCT02691013)
Timeframe: Twice daily for up to 10 days
| Intervention | hours (Median) |
|---|---|
| Placebo | 16 |
| Ramelteon | 24 |
(NCT02691013)
Timeframe: Duration of hospital admission
| Intervention | days (Median) |
|---|---|
| Placebo | 12 |
| Ramelteon | 12 |
(NCT02691013)
Timeframe: Duration of hospital admission
| Intervention | days (Median) |
|---|---|
| Placebo | 4 |
| Ramelteon | 4 |
Measured twice daily over the course of the ICU stay using the Confusion Assessment Method instrument (NCT02691013)
Timeframe: Twice daily for up to 10 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo | 22 |
| Ramelteon | 19 |
44 reviews available for melatonin and Inadequate Sleep
| Article | Year |
|---|---|
Obesity and Sleep.
Topics: Appetite; Ghrelin; Humans; Leptin; Melatonin; Obesity; Sleep; Sleep Deprivation; Stress, Psychologic | 2021 |
[Chronotherapy of affective disorders: principles and clinical aspects].
Topics: Bipolar Disorder; Chronotherapy; Humans; Melatonin; Mood Disorders; Sleep; Sleep Deprivation; Sleep | 2022 |
The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review.
Topics: Chronobiology Disorders; Delirium; Humans; Indenes; Intensive Care Units; Melatonin; Receptors, Mela | 2020 |
Optimising sleep and performance during night float: A systematic review of evidence and implications for graduate medical education trainees.
Topics: Adaptation, Physiological; Attention; Caffeine; Education, Medical, Graduate; Energy Drinks; Fatigue | 2021 |
Biological rhythms and chronotherapeutics in depression.
Topics: Animals; Chronotherapy; Circadian Rhythm; Cognitive Behavioral Therapy; Depression; Drug Chronothera | 2021 |
Melatonin for non-operating room sedation in paediatric population: a systematic review and meta-analysis.
Topics: Adolescent; Audiometry, Evoked Response; Child; Child, Preschool; Chloral Hydrate; Electroencephalog | 2022 |
Dietary Sources and Bioactivities of Melatonin.
Topics: Biological Availability; Circadian Rhythm; Diet; Humans; Melatonin; Nutrition Policy; Randomized Con | 2017 |
Neuroendocrine aspects of improving sleep in epilepsy.
Topics: Animals; Circadian Rhythm; Epilepsy; Humans; Melatonin; Neurosecretory Systems; Receptors, GABA; Sle | 2018 |
The role of sleep deprivation and circadian rhythm disruption as risk factors of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Circadian Rhythm; Glymphatic System; Humans; Melatonin; Oxidative Stress | 2019 |
Manipulating melatonin in managing mood.
Topics: Circadian Rhythm; Humans; Melatonin; Mood Disorders; Phototherapy; Sleep Deprivation | 2013 |
Out of synch with society: an update on delayed sleep phase disorder.
Topics: Benzofurans; Circadian Rhythm; Cyclopropanes; Environmental Exposure; Homeostasis; Humans; Light; Me | 2014 |
Impacts of shift work on sleep and circadian rhythms.
Topics: Accidents; Arousal; Automobile Driving; Cardiovascular Diseases; Circadian Rhythm; Circadian Rhythm | 2014 |
Restless legs syndrome and pain disorders: what's in common?
Topics: Calcium Channel Blockers; Diagnosis, Differential; Dopamine Agonists; Fibromyalgia; gamma-Aminobutyr | 2014 |
Emerging Role of Melatonin and Melatonin Receptor Agonists in Sleep and Delirium in Intensive Care Unit Patients.
Topics: Central Nervous System Depressants; Critical Care; Critical Illness; Delirium; Humans; Indenes; Inte | 2016 |
The bipolarity of light and dark: A review on Bipolar Disorder and circadian cycles.
Topics: Acetamides; Affect; Antimanic Agents; Bipolar Disorder; Circadian Rhythm; Humans; Hypnotics and Seda | 2015 |
Circadian disruption of ICU patients: A review of pathways, expression, and interventions.
Topics: Chronobiology Disorders; Circadian Rhythm; Clinical Alarms; Critical Care; Critical Illness; Humans; | 2017 |
Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption.
Topics: Circadian Rhythm; Humans; Light; Lighting; Melatonin; Sleep Deprivation | 2017 |
Managing jet lag: Some of the problems and possible new solutions.
Topics: Adaptation, Physiological; Circadian Rhythm; Combined Modality Therapy; Genetic Predisposition to Di | 2009 |
[Depression and circadian rhythm].
Topics: Biological Clocks; Circadian Rhythm; Depressive Disorder; Humans; Melatonin; Seasonal Affective Diso | 2009 |
[Schizophrenia and circadian rhythms].
Topics: Acute Disease; Antipsychotic Agents; Circadian Rhythm; Humans; Melatonin; Recurrence; Schizophrenia; | 2009 |
Melatonin and its agonists, circadian rhythms and psychiatry.
Topics: Adult; Aged; Central Nervous System Depressants; Child; Circadian Rhythm; Humans; Melatonin; Mental | 2009 |
[Depression as chronobiological illness].
Topics: Acetamides; Affect; Biological Clocks; Chronotherapy; Circadian Rhythm; Depression; Depressive Disor | 2009 |
Light-mediated perturbations of circadian timing and cancer risk: a mechanistic analysis.
Topics: Circadian Rhythm; Humans; Light; Melatonin; Neoplasms; Risk Factors; Sleep Deprivation | 2009 |
Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression.
Topics: Adolescent; Adult; Animals; Child; Chronobiology Disorders; Comorbidity; Disease Models, Animal; Hum | 2012 |
Chronic sleep deprivation and seasonality: implications for the obesity epidemic.
Topics: Adipose Tissue, Brown; Adult; Aged; Animals; Energy Intake; Energy Metabolism; Female; Hibernation; | 2011 |
Potential use of melatonin in sleep and delirium in the critically ill.
Topics: Central Nervous System Depressants; Critical Care; Critical Illness; Delirium; Humans; Intensive Car | 2012 |
Potential use of melatonin in sleep and delirium in the critically ill.
Topics: Central Nervous System Depressants; Critical Care; Critical Illness; Delirium; Humans; Intensive Car | 2012 |
Potential use of melatonin in sleep and delirium in the critically ill.
Topics: Central Nervous System Depressants; Critical Care; Critical Illness; Delirium; Humans; Intensive Car | 2012 |
Potential use of melatonin in sleep and delirium in the critically ill.
Topics: Central Nervous System Depressants; Critical Care; Critical Illness; Delirium; Humans; Intensive Car | 2012 |
Diet promotes sleep duration and quality.
Topics: Diet; Humans; Melatonin; Serotonin; Sleep; Sleep Deprivation; Tryptophan | 2012 |
Interacting epidemics? Sleep curtailment, insulin resistance, and obesity.
Topics: Adiponectin; Appetite; Diabetes Mellitus; Energy Metabolism; Female; Ghrelin; Glucose; Humans; Insul | 2012 |
Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation.
Topics: Cell Cycle; Circadian Rhythm; Epigenesis, Genetic; Humans; Light; Melatonin; Neoplasms; Risk Factors | 2013 |
Effect of airline travel on performance: a review of the literature.
Topics: Air Travel; Altitude; Athletic Performance; Benzodiazepines; Central Nervous System Depressants; Cir | 2013 |
Melatonin for the treatment of disorders in circadian rhythm and sleep: could it form a basis for medication?
Topics: Circadian Rhythm; Humans; Jet Lag Syndrome; Melatonin; Sleep; Sleep Deprivation; Sleep Disorders, Ci | 2003 |
Melatonin for treatment of sleep disorders.
Topics: Adult; Humans; Melatonin; Sleep; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Slee | 2004 |
[Does exogenous melatonin prove to be effective in the prevention and treatment of pathologies associated with shift and night work?].
Topics: Adaptation, Physiological; Circadian Rhythm; Humans; Melatonin; Personnel Staffing and Scheduling; S | 2005 |
Sleep in acute care units.
Topics: Acute Disease; Chronobiology Disorders; Cues; Electroencephalography; Environment; Health Personnel; | 2006 |
Biological rhythm disturbances in mood disorders.
Topics: Acetamides; Antidepressive Agents; Biological Clocks; Circadian Rhythm; Clinical Trials as Topic; De | 2006 |
Sleep, rhythms and women's mood. Part I. Menstrual cycle, pregnancy and postpartum.
Topics: Affect; Body Temperature; Female; Humans; Hydrocortisone; Melatonin; Menstrual Cycle; Postpartum Per | 2006 |
Prevention and treatment of sleep deprivation among emergency physicians.
Topics: Central Nervous System Stimulants; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; Med | 2007 |
Sleep in the intensive care unit.
Topics: Circadian Rhythm; Delirium; Humans; Hypnotics and Sedatives; Immunocompetence; Injury Severity Score | 2008 |
Sleep in the intensive care unit.
Topics: Circadian Rhythm; Delirium; Humans; Hypnotics and Sedatives; Immunocompetence; Injury Severity Score | 2008 |
Sleep in the intensive care unit.
Topics: Circadian Rhythm; Delirium; Humans; Hypnotics and Sedatives; Immunocompetence; Injury Severity Score | 2008 |
Sleep in the intensive care unit.
Topics: Circadian Rhythm; Delirium; Humans; Hypnotics and Sedatives; Immunocompetence; Injury Severity Score | 2008 |
Clinical and biological correlates of sleep deprivation in depression.
Topics: Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Homovanillic Acid; Humans; Hydrocortisone; | 1984 |
Light in the built environment: potential role of circadian disruption in endocrine disruption and breast cancer.
Topics: Adult; Breast Neoplasms; Circadian Rhythm; Developed Countries; Endocrine Glands; Environmental Expo | 2001 |
Sleep, sleepiness, and alcohol use.
Topics: Alcohol Drinking; Alcoholism; Animals; Dose-Response Relationship, Drug; Ethanol; Humans; Melatonin; | 2001 |
Light therapy of depression; basal and clinical aspects.
Topics: Animals; Circadian Rhythm; Humans; Melatonin; Phototherapy; Seasonal Affective Disorder; Sleep Depri | 1992 |
Affective disorders and circadian rhythms.
Topics: Affect; Antidepressive Agents; Bipolar Disorder; Body Temperature; Circadian Rhythm; Cues; Depressiv | 1986 |
Light therapy and psychiatry.
Topics: Atenolol; Circadian Rhythm; Depression; Depressive Disorder; Humans; Light; Melatonin; Mental Disord | 1986 |
33 trials available for melatonin and Inadequate Sleep
| Article | Year |
|---|---|
The acute effects of sleep restriction therapy for insomnia on circadian timing and vigilance.
Topics: Adult; Attention; Circadian Rhythm; Female; Humans; Male; Melatonin; Middle Aged; Sleep; Sleep Depri | 2021 |
Melatonin supplementation improves psychomotor and physical performance in collegiate student-athletes following a sleep deprivation night.
Topics: Adolescent; Adult; Athletes; Circadian Rhythm; Dietary Supplements; Double-Blind Method; Humans; Mal | 2021 |
Melatonin and Sleep in Preventing Hospitalized Delirium: A Randomized Clinical Trial.
Topics: Aged; Aged, 80 and over; Antioxidants; California; Delirium; Double-Blind Method; Female; Hospitaliz | 2018 |
Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation.
Topics: Adult; Central Nervous System Agents; CLOCK Proteins; Cross-Over Studies; Double-Blind Method; Human | 2018 |
Influence of Exercise Time of Day on Salivary Melatonin Responses.
Topics: Cross-Over Studies; Exercise; Humans; Male; Melatonin; Oxygen Consumption; Running; Saliva; Sleep; S | 2019 |
Advanced sleep schedules affect circadian gene expression in young adults with delayed sleep schedules.
Topics: Actigraphy; Adolescent; Adult; Circadian Rhythm; Circadian Rhythm Signaling Peptides and Proteins; F | 2013 |
Insights into behavioral vulnerability to differential sleep pressure and circadian phase from a functional ADA polymorphism.
Topics: Adenosine Deaminase; Adult; Analysis of Variance; Circadian Rhythm; Cross-Over Studies; Female; Gene | 2014 |
Prolonged sleep deprivation and continuous exercise: effects on melatonin, tympanic temperature, and cognitive function.
Topics: Adult; Body Temperature; Cognition; Ear, Middle; Exercise; Female; Humans; Male; Melatonin; Running; | 2014 |
Impact of oral melatonin on critically ill adult patients with ICU sleep deprivation: study protocol for a randomized controlled trial.
Topics: Administration, Oral; Biomarkers; China; Circadian Rhythm; Clinical Protocols; Critical Illness; Dou | 2014 |
Millisecond flashes of light phase delay the human circadian clock during sleep.
Topics: Adult; Circadian Clocks; Circadian Rhythm; Darkness; Female; Humans; Light; Male; Melatonin; Phototh | 2014 |
Millisecond flashes of light phase delay the human circadian clock during sleep.
Topics: Adult; Circadian Clocks; Circadian Rhythm; Darkness; Female; Humans; Light; Male; Melatonin; Phototh | 2014 |
Millisecond flashes of light phase delay the human circadian clock during sleep.
Topics: Adult; Circadian Clocks; Circadian Rhythm; Darkness; Female; Humans; Light; Male; Melatonin; Phototh | 2014 |
Millisecond flashes of light phase delay the human circadian clock during sleep.
Topics: Adult; Circadian Clocks; Circadian Rhythm; Darkness; Female; Humans; Light; Male; Melatonin; Phototh | 2014 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
Effect of oral melatonin and wearing earplugs and eye masks on nocturnal sleep in healthy subjects in a simulated intensive care unit environment: which might be a more promising strategy for ICU sleep deprivation?
Topics: Adult; Central Nervous System Depressants; Ear Protective Devices; Environmental Exposure; Eye Prote | 2015 |
An experimental study of adolescent sleep restriction during a simulated school week: changes in phase, sleep staging, performance and sleepiness.
Topics: Adolescent; Attention; Circadian Rhythm; Female; Humans; Male; Melatonin; Polysomnography; Saliva; S | 2017 |
Late, but not early, wake therapy reduces morning plasma melatonin: relationship to mood in Premenstrual Dysphoric Disorder.
Topics: Adult; Affect; Circadian Rhythm; Female; Humans; Melatonin; Menstrual Cycle; Premenstrual Syndrome; | 2008 |
Excess diuresis and natriuresis during acute sleep deprivation in healthy adults.
Topics: Acute Disease; Adolescent; Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriure | 2010 |
Melatonin does not influence sleep deprivation electroencephalogram recordings in children.
Topics: Adolescent; Central Nervous System Depressants; Child, Preschool; Electroencephalography; Epilepsy; | 2012 |
Sympathetic activity and hypothalamo-pituitary-adrenal axis activity during sleep in post-traumatic stress disorder: a study assessing polysomnography with simultaneous blood sampling.
Topics: Adrenocorticotropic Hormone; Adult; Blood Specimen Collection; Circadian Rhythm; Dreams; Heart Rate; | 2013 |
Evening ambient light exposure can reduce circadian phase advances to morning light independent of sleep deprivation.
Topics: Adult; Circadian Rhythm; Female; Humans; Male; Melatonin; Photic Stimulation; Polysomnography; Saliv | 2013 |
Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelated.
Topics: Adult; Attention; Blood Glucose; Electroencephalography; Humans; Male; Melatonin; Reproducibility of | 2003 |
Melatonin treatment of winter depression following total sleep deprivation: waking EEG and mood correlates.
Topics: Adolescent; Adult; Affect; Case-Control Studies; Disorders of Excessive Somnolence; Double-Blind Met | 2005 |
Bright green light treatment of depression for older adults [ISRCTN69400161].
Topics: Adult; Age Factors; Aged; Circadian Rhythm; Clinical Protocols; Color; Depressive Disorder, Major; F | 2005 |
Exposure to bright light modifies HRV responses to mental tasks during nocturnal sleep deprivation.
Topics: Adult; Attention; Blood Pressure; Body Temperature; Circadian Rhythm; Heart Rate; Humans; Light; Mal | 2006 |
Creatine supplementation, sleep deprivation, cortisol, melatonin and behavior.
Topics: Adult; Affect; Analysis of Variance; Attention; Cognition; Creatine; Dietary Supplements; Double-Bli | 2007 |
Late evening brain activation patterns and their relation to the internal biological time, melatonin, and homeostatic sleep debt.
Topics: Adult; Arousal; Biological Clocks; Brain; Brain Mapping; Circadian Rhythm; Cross-Over Studies; Doubl | 2009 |
Improving adaptation to simulated night shift: timed exposure to bright light versus daytime melatonin administration.
Topics: Adolescent; Adult; Body Temperature; Circadian Rhythm; Cognition; Female; Humans; Light; Male; Melat | 1995 |
Selective slow-wave sleep deprivation influences blood serotonin profiles and serum melatonin concentrations in healthy subjects.
Topics: Adult; Humans; Male; Melatonin; Polysomnography; Reference Values; Serotonin; Sleep Deprivation; Sle | 1996 |
Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans.
Topics: Adolescent; Adult; Body Temperature; Caffeine; Central Nervous System Stimulants; Depression, Chemic | 1997 |
Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans.
Topics: Adolescent; Adult; Body Temperature; Caffeine; Central Nervous System Stimulants; Depression, Chemic | 1997 |
Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans.
Topics: Adolescent; Adult; Body Temperature; Caffeine; Central Nervous System Stimulants; Depression, Chemic | 1997 |
Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans.
Topics: Adolescent; Adult; Body Temperature; Caffeine; Central Nervous System Stimulants; Depression, Chemic | 1997 |
Effect of modafinil on plasma melatonin, cortisol and growth hormone rhythms, rectal temperature and performance in healthy subjects during a 36 h sleep deprivation.
Topics: Adult; Benzhydryl Compounds; Body Temperature; Central Nervous System Stimulants; Health Status; Hum | 1998 |
Jet lag: clinical features, validation of a new syndrome-specific scale, and lack of response to melatonin in a randomized, double-blind trial.
Topics: Aerospace Medicine; Circadian Rhythm; Double-Blind Method; Health Status; Humans; Melatonin; Placebo | 1999 |
Effects of menstrual cycle phase and oral contraceptives on alertness, cognitive performance, and circadian rhythms during sleep deprivation.
Topics: Adolescent; Adult; Analysis of Variance; Arousal; Attention; Body Temperature; Circadian Rhythm; Cog | 1999 |
Effect of melatonin on sleep quality of COPD intensive care patients: a pilot study.
Topics: Adult; Aged; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Intensive Care Units; | 2000 |
Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans.
Topics: Adult; Aged; Electroencephalography; Female; Human Growth Hormone; Humans; Hydrocortisone; Interleuk | 2000 |
Melatonin is useful for recording sleep EEGs: a prospective audit of outcome.
Topics: Antioxidants; Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Melatonin; Slee | 2001 |
Melatonin is useful for recording sleep EEGs: a prospective audit of outcome.
Topics: Antioxidants; Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Melatonin; Slee | 2001 |
Melatonin is useful for recording sleep EEGs: a prospective audit of outcome.
Topics: Antioxidants; Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Melatonin; Slee | 2001 |
Melatonin is useful for recording sleep EEGs: a prospective audit of outcome.
Topics: Antioxidants; Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Melatonin; Slee | 2001 |
The use of melatonin as an alternative to sedation in uncooperative children undergoing an MRI examination.
Topics: Adolescent; Child; Child Behavior; Child, Preschool; Conscious Sedation; Cooperative Behavior; Femal | 2002 |
144 other studies available for melatonin and Inadequate Sleep
| Article | Year |
|---|---|
Right stellate ganglion block improves learning and memory dysfunction and hippocampal injury in rats with sleep deprivation.
Topics: Animals; Autonomic Nerve Block; Hippocampus; Male; Melatonin; Memory Disorders; Neurons; Rats; Rats, | 2021 |
Melatonin-Mediated Colonic Microbiota Metabolite Butyrate Prevents Acute Sleep Deprivation-Induced Colitis in Mice.
Topics: Animals; Antioxidants; Butyrates; Colitis; Colon; Fecal Microbiota Transplantation; Male; Melatonin; | 2021 |
No Effect of Chronotype on Hunger or Snack Consumption during a Night Shift with Acute Sleep Deprivation.
Topics: Adult; Circadian Rhythm; Humans; Hunger; Melatonin; Prospective Studies; Sleep; Sleep Deprivation; S | 2022 |
Homeostatic response to sleep deprivation and circadian rhythmicity are intact in older adults with insomnia.
Topics: Aged; Circadian Rhythm; Electroencephalography; Humans; Melatonin; Sleep; Sleep Deprivation; Sleep I | 2022 |
Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats.
Topics: Animals; Depression; Hippocampus; Melatonin; Neuronal Plasticity; Pineal Gland; Rats; Sleep Deprivat | 2022 |
Melatonin protects against body weight gain induced by sleep deprivation in mice.
Topics: Animals; Body Weight; Circadian Rhythm; Melatonin; Mice; Obesity; Sleep; Sleep Deprivation; Weight G | 2022 |
Melatonin upregulates BMAL1 to attenuate chronic sleep deprivation-related cognitive impairment by alleviating oxidative stress.
Topics: ARNTL Transcription Factors; bcl-2-Associated X Protein; Cognitive Dysfunction; Humans; Interleukin- | 2023 |
Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation.
Topics: Animals; Butyrates; Clostridiales; Cognitive Dysfunction; Gastrointestinal Microbiome; Lipopolysacch | 2023 |
Paternal sleep deprivation induces metabolic perturbations in male offspring via altered LRP5 DNA methylation of pancreatic islets.
Topics: Animals; Cyclin D1; Cyclin D2; Diabetes Mellitus; DNA Methylation; Fathers; Glucose Intolerance; Hum | 2023 |
The impact of daylight-saving time (DST) on patients with delayed sleep-wake phase disorder (DSWPD).
Topics: Circadian Rhythm; Female; Humans; Male; Melatonin; Sleep; Sleep Deprivation; Time | 2023 |
Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague-Dawley rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Fetus; Interleukin-6; Melatonin; Place | 2023 |
Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injury.
Topics: Animals; Disease Models, Animal; Enteritis; Intestinal Mucosa; Intestine, Small; Male; Melatonin; Mi | 2020 |
Top 10 evidence-based countermeasures for night shift workers.
Topics: Caffeine; Circadian Rhythm; Eating; Efficiency; Emergency Service, Hospital; Fatigue; Female; Humans | 2020 |
Melatonin attenuates microbiota dysbiosis of jejunum in short-term sleep deprived mice.
Topics: Aeromonadaceae; Animals; Antioxidants; Bacteroidaceae; Dysbiosis; Firmicutes; Gastrointestinal Micro | 2020 |
Screening of sleep assisting drug candidates with a Drosophila model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Circadian Rhythm; Disease Models, Animal; Drosoph | 2020 |
The impact of structured sleep schedules prior to an in-laboratory study: Individual differences in sleep and circadian timing.
Topics: Adult; Circadian Rhythm; Female; Humans; Individuality; Light; Male; Melatonin; Middle Aged; Saliva; | 2020 |
Sleep deprivation aggravated lipopolysaccharide/D-galactosamine-induced acute liver injury by suppressing melatonin production.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caspases; Chemical and Drug Induced Live | 2020 |
The impact of the wake maintenance zone on attentional capacity, physiological drowsiness, and subjective task demands during sleep deprivation.
Topics: Adult; Attention; Circadian Rhythm; Humans; Male; Melatonin; Sleep; Sleep Deprivation; Wakefulness; | 2021 |
Sleep deprivation therapy to reset the circadian pacemaker in a non-24-hour sleep-wake disorder: a case report.
Topics: Circadian Rhythm; Humans; Male; Melatonin; Sleep; Sleep Deprivation; Sleep Disorders, Circadian Rhyt | 2021 |
Melatonin ameliorates anxiety-like behaviors induced by sleep deprivation in mice: Role of oxidative stress, neuroinflammation, autophagy and apoptosis.
Topics: Animals; Antioxidants; Anxiety; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Calcium-Binding | 2021 |
Melatonin Ameliorates Corticosterone-Mediated Oxidative Stress-Induced Colitis in Sleep-Deprived Mice Involving Gut Microbiota.
Topics: Animals; Antioxidants; Colitis; Corticosterone; Disease Models, Animal; Gastrointestinal Microbiome; | 2021 |
Young children with Down syndrome show normal development of circadian rhythms, but poor sleep efficiency: a cross-sectional study across the first 60 months of life.
Topics: Actigraphy; Child; Child, Preschool; Circadian Rhythm; Cross-Sectional Studies; Down Syndrome; Femal | 2017 |
Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness.
Topics: Adult; Age Factors; Aged; Attention; Circadian Rhythm; Cross-Over Studies; Female; Humans; Hydrocort | 2017 |
Melatonin prevents memory impairment induced by high-fat diet: Role of oxidative stress.
Topics: Animals; Antioxidants; Diet, High-Fat; Hippocampus; Male; Maze Learning; Melatonin; Memory Disorders | 2018 |
Sleep duration, nightshift work, and the timing of meals and urinary levels of 8-isoprostane and 6-sulfatoxymelatonin in Japanese women.
Topics: Adult; Biomarkers; Breakfast; Breast Neoplasms; Circadian Rhythm; Dinoprost; Eating; Feeding Behavio | 2017 |
Inactivity Is Nycthemeral, Endogenously Generated, Homeostatically Regulated, and Melatonin Modulated in a Free-Living Platyhelminth Flatworm.
Topics: Animals; Biological Evolution; Circadian Rhythm; Homeostasis; Melatonin; Motor Activity; Phylogeny; | 2017 |
Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon.
Topics: Activity Cycles; Animals; Circadian Rhythm; Colon; Light; Melatonin; Motor Activity; Photoperiod; Ra | 2017 |
Estimating adolescent sleep need using dose-response modeling.
Topics: Adolescent; Attention; Circadian Rhythm; Female; Homeostasis; Humans; Male; Melatonin; Sleep; Sleep | 2018 |
Sleep deprivation and melatonin for inducing sleep in paediatric electroencephalography: a prospective multicentre service evaluation.
Topics: Adolescent; Brain; Brain Waves; Chi-Square Distribution; Child; Child, Preschool; Electroencephalogr | 2019 |
Sleep deprivation versus melatonin to induce sleep during paediatric electroencephalography.
Topics: Child; Electroencephalography; Humans; Melatonin; Prospective Studies; Sleep; Sleep Deprivation | 2019 |
Role of melatonin in sleep deprivation-induced intestinal barrier dysfunction in mice.
Topics: Animals; Colon; Gastrointestinal Microbiome; Intestinal Diseases; Intestinal Mucosa; Male; Melatonin | 2019 |
Effect of acute total sleep deprivation on plasma melatonin, cortisol and metabolite rhythms in females.
Topics: Circadian Rhythm; Female; Humans; Hydrocortisone; Male; Melatonin; Sleep; Sleep Deprivation | 2020 |
Neuroprotective effect of exogenous melatonin on the noradrenergic neurons of adult male rats' locus coeruleus nucleus following REM sleep deprivation.
Topics: Adrenergic Neurons; Animals; Locus Coeruleus; Male; Melatonin; Neuroprotective Agents; Rats; Rats, W | 2019 |
Insufficient sleep associated with increased breast cancer mortality.
Topics: Adult; Breast Neoplasms; Female; Humans; Melatonin; Prevalence; Risk Factors; Sleep Deprivation | 2013 |
Improved neurobehavioral performance during the wake maintenance zone.
Topics: Adolescent; Adult; Circadian Rhythm; Cognition; Female; Humans; Male; Melatonin; Polysomnography; Ps | 2013 |
Perspective: casting light on sleep deficiency.
Topics: Circadian Rhythm; Electricity; Humans; Jet Lag Syndrome; Lighting; Melatonin; Phototherapy; Sleep De | 2013 |
Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans.
Topics: Adult; ARNTL Transcription Factors; Circadian Rhythm; Gene Expression Profiling; Gene Expression Reg | 2013 |
Melatonin ameliorates cognitive impairment induced by sleep deprivation in rats: role of oxidative stress, BDNF and CaMKII.
Topics: Animals; Antioxidants; Brain; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protei | 2013 |
Melatonin attenuates dextran sodium sulfate induced colitis with sleep deprivation: possible mechanism by microarray analysis.
Topics: Animals; Body Weight; Colitis; Colon; Dextran Sulfate; DNA; Gene Expression Regulation; Melatonin; M | 2014 |
Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency.
Topics: Age Factors; Animals; Calcium Signaling; Cyclic AMP Response Element-Binding Protein; Male; Melatoni | 2015 |
Sleep loss, circadian mismatch, and abnormalities in reorienting of attention in night workers with shift work disorder.
Topics: Adult; Attention; Brain; Circadian Rhythm; Evoked Potentials; Female; Hospitals; Humans; Light; Male | 2014 |
Atopic dermatitis, melatonin, and sleep disturbance.
Topics: Actigraphy; Child; Child, Preschool; Comorbidity; Cross-Sectional Studies; Cytokines; Dermatitis, At | 2014 |
Is melatonin the next "new" therapy to improve sleep and reduce pain?
Topics: Animals; Male; Median Nerve; Melatonin; Microglia; Neuralgia; Sleep Deprivation | 2014 |
Sleep deprivation aggravates median nerve injury-induced neuropathic pain and enhances microglial activation by suppressing melatonin secretion.
Topics: Animals; Cytokines; Inflammation Mediators; Male; Median Nerve; Medulla Oblongata; Melatonin; Microg | 2014 |
Sleep disorders and inflammatory disease activity: chicken or the egg?
Topics: Animals; C-Reactive Protein; Circadian Rhythm; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 2015 |
Impact of circadian misalignment on energy metabolism during simulated nightshift work.
Topics: Adult; Analysis of Variance; Circadian Rhythm; Eating; Electromyography; Energy Metabolism; Female; | 2014 |
Impact of circadian misalignment on energy metabolism during simulated nightshift work.
Topics: Adult; Analysis of Variance; Circadian Rhythm; Eating; Electromyography; Energy Metabolism; Female; | 2014 |
Impact of circadian misalignment on energy metabolism during simulated nightshift work.
Topics: Adult; Analysis of Variance; Circadian Rhythm; Eating; Electromyography; Energy Metabolism; Female; | 2014 |
Impact of circadian misalignment on energy metabolism during simulated nightshift work.
Topics: Adult; Analysis of Variance; Circadian Rhythm; Eating; Electromyography; Energy Metabolism; Female; | 2014 |
Occurrence of epileptiform discharges and sleep during EEG recordings in children after melatonin intake versus sleep-deprivation.
Topics: Adolescent; Brain; Central Nervous System Depressants; Child; Child, Preschool; Electroencephalograp | 2015 |
Length polymorphism in the Period 3 gene is associated with sleepiness and maladaptive circadian phase in night-shift workers.
Topics: Adult; Alleles; Case-Control Studies; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Peri | 2015 |
Melatonin improves experimental colitis with sleep deprivation.
Topics: Animals; Body Weight; Colitis; Cytokines; Disease Models, Animal; Gene Expression Profiling; Inflamm | 2015 |
Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance.
Topics: Adult; Biomarkers; C-Reactive Protein; Circadian Rhythm; Female; Humans; Hydrocortisone; Interleukin | 2015 |
Inter-Individual Differences in Neurobehavioural Impairment following Sleep Restriction Are Associated with Circadian Rhythm Phase.
Topics: Adolescent; Adult; Affect; Behavior; Circadian Rhythm; Female; Humans; Male; Melatonin; Nervous Syst | 2015 |
The potential role of melatonin on sleep deprivation-induced cognitive impairments: implication of FMRP on cognitive function.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antioxidants; Brain; Cell Survival; Cells, Cultured | 2015 |
Chronic Melatonin Treatment Prevents Memory Impairment Induced by Chronic Sleep Deprivation.
Topics: Animals; Biomarkers; Chronic Disease; Hippocampus; Male; Maze Learning; Melatonin; Memory; Memory Di | 2016 |
Effects of vitamin E and melatonin on serum testosterone level in sleep deprived Wistar rats.
Topics: Animals; Body Weight; Corticosterone; Male; Malondialdehyde; Melatonin; Organ Size; Oxidative Stress | 2014 |
Nocturnal light pollution and underexposure to daytime sunlight: Complementary mechanisms of circadian disruption and related diseases.
Topics: Animals; Breast Neoplasms; Circadian Rhythm; Female; Humans; Lighting; Male; Melatonin; Prostatic Ne | 2015 |
Dissecting Daily and Circadian Expression Rhythms of Clock-Controlled Genes in Human Blood.
Topics: Adolescent; Adult; Circadian Clocks; Circadian Rhythm; CLOCK Proteins; Fasting; Female; Gene Express | 2016 |
Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity.
Topics: Adolescent; Adult; Circadian Rhythm; Female; Glucose; Humans; Insulin; Insulin Resistance; Male; Mel | 2015 |
Effects of a single night of postpartum sleep on childless women's daytime functioning.
Topics: Adolescent; Adult; Affect; Analysis of Variance; Female; Humans; Melatonin; Polysomnography; Postpar | 2016 |
Melatonin Supplementation to Prevent Delirium in Hospitalized Elderly Patients.
Topics: Aged; Central Nervous System Depressants; Delirium; Geriatric Assessment; Hospitalization; Humans; I | 2016 |
Local modulation of human brain responses by circadian rhythmicity and sleep debt.
Topics: Adolescent; Adult; Attention; Cerebral Cortex; Circadian Rhythm; Cognition; Female; Humans; Magnetic | 2016 |
Prophylactic Role of Oral Melatonin Administration on Neurogenesis in Adult Balb/C Mice during REM Sleep Deprivation.
Topics: Administration, Oral; Animals; bcl-X Protein; Cell Proliferation; Central Nervous System Depressants | 2016 |
Melatonin modulates adiponectin expression on murine colitis with sleep deprivation.
Topics: Adiponectin; Animals; Antibodies; Body Weight; Colitis; Cytokines; Enzyme-Linked Immunosorbent Assay | 2016 |
Circadian timing and alignment in healthy adults: associations with BMI, body fat, caloric intake and physical activity.
Topics: Actigraphy; Adipose Tissue; Adult; Body Mass Index; Circadian Rhythm; Diet Records; Energy Intake; E | 2017 |
The association between artificial light at night and prostate cancer in Gwangju City and South Jeolla Province of South Korea.
Topics: Circadian Rhythm; Cities; Geography; Humans; Incidence; Light; Male; Melatonin; Prostatic Neoplasms; | 2017 |
Sleep during an Antarctic summer expedition: new light on "polar insomnia".
Topics: Acclimatization; Affect; Antarctic Regions; Arousal; Circadian Rhythm; Expeditions; Humans; Hydrocor | 2017 |
Melatonin attenuates lipopolysaccharide-induced acute lung inflammation in sleep-deprived mice.
Topics: Analysis of Variance; Animals; Body Weight; Histocytochemistry; In Situ Nick-End Labeling; Lipid Per | 2009 |
Early morning executive functioning during sleep deprivation is compromised by a PERIOD3 polymorphism.
Topics: Adult; Arousal; Attention; Circadian Rhythm; Female; Genetic Markers; Genotype; Homeostasis; Homozyg | 2008 |
Sleep disorders: causes, effects, and solutions.
Topics: Behavior Therapy; Chronobiology Disorders; Drug Interactions; Drug-Related Side Effects and Adverse | 2008 |
Interaction of chronic sleep restriction and circadian system in humans.
Topics: Adult; Chronic Disease; Female; Humans; Male; Melatonin; Sleep Deprivation; Sleep Disorders, Circadi | 2008 |
Subjective well-being is modulated by circadian phase, sleep pressure, age, and gender.
Topics: Adult; Affect; Age Factors; Aged; Biological Clocks; Circadian Rhythm; Cross-Over Studies; Female; H | 2009 |
Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Central Nervous System Depressants; Corticosteron | 2009 |
The effect of 40 h constant wakefulness on task-switching efficiency.
Topics: Adult; Arousal; Attention; Circadian Rhythm; Decision Making; Discrimination, Psychological; Efficie | 2009 |
Circadian rhythm in handwriting.
Topics: Adult; Attention; Biomechanical Phenomena; Circadian Rhythm; Handwriting; Humans; Male; Melatonin; M | 2009 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Fem | 2009 |
Constant light induces alterations in melatonin levels, food intake, feed efficiency, visceral adiposity, and circadian rhythms in rats.
Topics: Adaptation, Psychological; Adiposity; Algorithms; Animals; Body Weight; Circadian Rhythm; Drinking; | 2009 |
Shift work and cancer - considerations on rationale, mechanisms, and epidemiology.
Topics: Breast Neoplasms; Chronobiology Disorders; Female; Humans; Male; Melatonin; Middle Aged; Occupationa | 2010 |
Circadian rhythms in handwriting kinematics and legibility.
Topics: Adult; Biomechanical Phenomena; Circadian Rhythm; Handwriting; Humans; Male; Melatonin; Motor Skills | 2011 |
Recognition and assessment of shift work disorder.
Topics: Animals; Biological Clocks; Circadian Rhythm; Diabetes Mellitus, Type 2; Energy Metabolism; Hormones | 2011 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Ac | 2011 |
Aging of intrinsic circadian rhythms and sleep in a diurnal nonhuman primate, Macaca mulatta.
Topics: Aging; Animals; Circadian Clocks; Circadian Rhythm; Longitudinal Studies; Macaca mulatta; Male; Mela | 2011 |
The effect of sleep restriction and psychological load on the diurnal metabolic changes in tryptamine-related compounds in human urine.
Topics: Adult; Analysis of Variance; Chromatography, High Pressure Liquid; Circadian Rhythm; Fatigue; Fluoro | 2012 |
Hypotheses for mechanisms linking shiftwork and cancer.
Topics: Humans; Life Style; Light; Melatonin; Models, Biological; Neoplasms; Risk Factors; Sleep Deprivation | 2011 |
Inhibition of hippocampal neurogenesis by sleep deprivation is independent of circadian disruption and melatonin suppression.
Topics: Adrenalectomy; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; | 2011 |
Maternal stress induces adult reduced REM sleep and melatonin level.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Male; Maternal Deprivation; Melatonin; Ra | 2012 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |
Melatonin improves inflammatory cytokine profiles in lung inflammation associated with sleep deprivation.
Topics: Animals; Bronchoalveolar Lavage; Central Nervous System Depressants; Cytokines; Humans; Lipopolysacc | 2012 |
Sleep and sleep disorders in the hospital.
Topics: Circadian Rhythm; Hospitalization; Humans; Melatonin; Polysomnography; Respiration, Artificial; Slee | 2012 |
Sleep duration, spot urinary 6-sulfatoxymelatonin levels and risk of breast cancer among Chinese women in Singapore.
Topics: Breast Neoplasms; Case-Control Studies; China; Female; Humans; Melatonin; Middle Aged; Risk Factors; | 2013 |
Effects of sleep fragmentation on appetite and related hormone concentrations over 24 h in healthy men.
Topics: Adult; Appetite; Appetite Regulation; Blood Glucose; Eating; Energy Metabolism; Ghrelin; Glucagon-Li | 2013 |
Transient total sleep loss in cerebral Whipple's disease: a longitudinal study.
Topics: Adult; Brain; Carrier Proteins; Circadian Rhythm; Electroencephalography; Fixation, Ocular; Fluorode | 2002 |
A longer biological night in long sleepers than in short sleepers.
Topics: Adult; Body Temperature; Circadian Rhythm; Female; Habits; Humans; Hydrocortisone; Individuality; Ma | 2003 |
Mood regulation in seasonal affective disorder patients and healthy controls studied in forced desynchrony.
Topics: Adult; Affect; Body Temperature; Chronobiology Disorders; Circadian Rhythm; Female; Humans; Male; Me | 2003 |
Human circadian melatonin rhythm phase delay during a fixed sleep-wake schedule interspersed with nights of sleep deprivation.
Topics: Biological Clocks; Circadian Rhythm; Humans; Melatonin; Sleep; Sleep Deprivation; Time Factors | 2003 |
Performance, sleep and circadian phase during a week of simulated night work.
Topics: Adolescent; Adult; Attention; Circadian Rhythm; Environment, Controlled; Female; Humans; Male; Melat | 2001 |
Daytime cardiac autonomic activity during one week of continuous night shift.
Topics: Adolescent; Adult; Arousal; Autonomic Nervous System; Cardiography, Impedance; Cardiovascular Diseas | 2001 |
Effect of bright light on EEG activities and subjective sleepiness to mental task during nocturnal sleep deprivation.
Topics: Adult; Analysis of Variance; Body Temperature; Electroencephalography; Fatigue; Humans; Intelligence | 2003 |
[Impact of sleep debt on physiological rhythms].
Topics: Adult; Convalescence; Electroencephalography; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System | 2003 |
Vigilance levels during and after bright light exposure in the first half of the night.
Topics: Adult; Attention; Body Temperature; Electroencephalography; Female; Humans; Hydrocortisone; Light; M | 2003 |
Circadian modulation of sequence learning under high and low sleep pressure conditions.
Topics: Adult; Analysis of Variance; Body Temperature; Circadian Rhythm; Female; Humans; Learning; Male; Mel | 2004 |
Prostaglandin D synthase (beta-trace) in healthy human sleep.
Topics: Adult; Circadian Rhythm; Cross-Over Studies; Disorders of Excessive Somnolence; Female; Humans; Intr | 2004 |
Diurnal fluctuation of time perception under 30-h sustained wakefulness.
Topics: Adult; Body Temperature; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; Pain Measurement | 2005 |
Sleep tendency during extended wakefulness: insights into adolescent sleep regulation and behavior.
Topics: Adolescent; Adolescent Behavior; Child; Circadian Rhythm; Electromyography; Female; Homeostasis; Hum | 2005 |
Effect of menopause on melatonin and alertness rhythms investigated in constant routine conditions.
Topics: Adult; Circadian Rhythm; Female; Habits; Humans; Melatonin; Menopause; Middle Aged; Postmenopause; P | 2005 |
Short nights reduce light-induced circadian phase delays in humans.
Topics: Adult; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Photoperiod; Sleep Deprivation; Tim | 2006 |
Nocturnal sustained attention during sleep deprivation can be predicted by specific periods of subjective daytime alertness in normal young humans.
Topics: Adult; Arousal; Attention; Body Temperature; Circadian Rhythm; Humans; Male; Melatonin; Periodicity; | 2006 |
Genetically increased risk of sleep disruption in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoproteins E; Base Pairing; Case-Control S | 2006 |
Diurnal urinary 6-sulfatoxymelatonin levels among healthy Danish nurses during work and leisure time.
Topics: Adult; Circadian Rhythm; Denmark; Employment; Female; Humans; Interviews as Topic; Melatonin; Middle | 2006 |
Plasma melatonin rhythms in young and older humans during sleep, sleep deprivation, and wake.
Topics: Adolescent; Adult; Aged; Aging; Body Temperature; Circadian Rhythm; Female; Humans; Male; Melatonin; | 2007 |
The use of sleep-facilitating substances by emergency physicians.
Topics: Adult; Attention; Drug Utilization; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedat | 2008 |
Critical interval hypotheses for depression.
Topics: Animals; Antidepressive Agents; Circadian Rhythm; Cricetinae; Depression; Humans; Light; Melatonin; | 1984 |
The circadian covariation of fatigue and urinary melatonin.
Topics: Adult; Arousal; Attention; Circadian Rhythm; Fatigue; Humans; Melatonin; Motion Perception; Sleep De | 1982 |
Role of melatonin in nocturnal prolactin secretion in women with normoprolactinemia and mild hyperprolactinemia.
Topics: Adult; Circadian Rhythm; Darkness; Female; Humans; Hyperprolactinemia; Light; Melatonin; Prolactin; | 1993 |
Overnight human plasma melatonin, cortisol, prolactin, TSH, under conditions of normal sleep, sleep deprivation, and sleep recovery.
Topics: Adult; Analysis of Variance; Humans; Hydrocortisone; Male; Melatonin; Pineal Gland; Prolactin; Radio | 1996 |
Twenty-four-hour melatonin and core body temperature rhythms: their adaptation in night workers.
Topics: Activity Cycles; Adult; Body Temperature; Body Temperature Regulation; Circadian Rhythm; Humans; Lig | 1997 |
Restoration of detectable melatonin after entrainment to a 24-hour schedule in a 'free-running' man.
Topics: Adult; Body Temperature Regulation; Circadian Rhythm; Dark Adaptation; Humans; Hydrocortisone; Hypot | 1997 |
Disruption of sleep recovery after 36 hours of exposure to moderately bright light.
Topics: Adult; Body Temperature; Electroencephalography; Electromyography; Homeostasis; Humans; Hydrocortiso | 1997 |
Daytime vigilance after morning bright light exposure in volunteers subjected to sleep restriction.
Topics: Adult; Attention; Circadian Rhythm; Female; Humans; Male; Melatonin; Phototherapy; Polysomnography; | 1998 |
Patients in the intensive care unit suffer from severe lack of sleep associated with loss of normal melatonin secretion pattern.
Topics: Adult; Aged; Case-Control Studies; Circadian Rhythm; Critical Care; Enzyme-Linked Immunosorbent Assa | 1999 |
Poor recovery sleep after sleep deprivation in delayed sleep phase syndrome.
Topics: Adult; Circadian Rhythm; Homeostasis; Humans; Male; Melatonin; Reference Values; Sleep Deprivation; | 1999 |
Correlation between the circadian sleep propensity rhythm and hormonal rhythms under ultra-short sleep-wake cycle.
Topics: Adult; Body Temperature Regulation; Circadian Rhythm; Female; Habits; Humans; Hydrocortisone; Melato | 1999 |
Diurnal preference, sleep habits, circadian sleep propensity and melatonin rhythm in healthy human subjects.
Topics: Adult; Circadian Rhythm; Female; Humans; Male; Melatonin; Motor Activity; Regression Analysis; Sleep | 2000 |
Melatonin treatment does not prevent decreases in brain glutathione levels induced by sleep deprivation.
Topics: Animals; Antioxidants; Brain; Glutathione; Hypothalamus; Male; Melatonin; Rats; Rats, Wistar; Sleep | 2000 |
Sleep-wake as a biological rhythm.
Topics: Circadian Rhythm; Humans; Light; Melatonin; Sleep Deprivation; Sleep Disorders, Circadian Rhythm | 2001 |
Therapeutic progress of two sibling cases exhibiting sleep-wake rhythm disorder.
Topics: Adolescent; Female; Humans; Melatonin; Polysomnography; Sleep Deprivation; Sleep Disorders, Circadia | 2000 |
Transition from dim to bright light in the morning induces an immediate elevation of cortisol levels.
Topics: Adult; Arousal; Circadian Rhythm; Cognition; Hormones; Humans; Hydrocortisone; Light; Male; Melatoni | 2001 |
Disruption of the nocturnal testosterone rhythm by sleep fragmentation in normal men.
Topics: Adult; Body Temperature; Circadian Rhythm; Humans; Male; Melatonin; Sleep Deprivation; Sleep, REM; T | 2001 |
Effects of one night of sleep deprivation on hormone profiles and performance efficiency.
Topics: Adult; Analysis of Variance; Behavior; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; Mi | 2001 |
Influence of sleep deprivation coupled with administration of melatonin on the ultrastructure of rat pineal gland.
Topics: Animals; Circadian Rhythm; Female; Intracellular Membranes; Male; Melatonin; Microscopy, Electron; N | 2001 |
Combating fatigue to enhance safety.
Topics: Accidents, Aviation; Aerospace Medicine; Caffeine; Circadian Rhythm; Ergonomics; Fatigue; Humans; Me | 1996 |
The melatonin hypothesis: a matter of method.
Topics: Antioxidants; Breast Neoplasms; Circadian Rhythm; Confounding Factors, Epidemiologic; Down-Regulatio | 2002 |
Non-rapid-eye-movement sleep propensity after sleep deprivation in human subjects.
Topics: Adult; Circadian Rhythm; Female; Humans; Male; Melatonin; Sleep Deprivation; Sleep Stages; Sleep, RE | 2002 |
Melatonin excretion, body temperature and subjective arousal during 64 hours of sleep deprivation.
Topics: Adult; Arousal; Body Temperature; Fatigue; Humans; Male; Melatonin; Sleep Deprivation | 1979 |
Urinary melatonin rhythms during sleep deprivation in depressed patients and normals.
Topics: Adult; Aged; Circadian Rhythm; Depression; Electroencephalography; Female; Humans; Lighting; Male; M | 1977 |
Circadian patterns of melatonin, corticosterone, and progesterone in male rats subjected to chronic stress: effect of constant illumination.
Topics: Animals; Circadian Rhythm; Corticosterone; Lighting; Male; Melatonin; Motor Activity; Pineal Gland; | 1991 |
Elevated rectal temperature produced by all-night bright light is reversed by melatonin infusion in men.
Topics: Adult; Body Temperature; Circadian Rhythm; Darkness; Humans; Light; Male; Melatonin; Sleep Deprivati | 1991 |
Melatonin and adrenal cortex steroid production: in vivo and in vitro studies.
Topics: Adrenal Cortex Hormones; Animals; Circadian Rhythm; Corticosterone; Light; Male; Melatonin; Pineal G | 1991 |
Green light attenuates melatonin output and sleepiness during sleep deprivation.
Topics: Adult; Arousal; Body Temperature Regulation; Circadian Rhythm; Color; Female; Humans; Lighting; Male | 1991 |
Sleep deprivation reduces LH secretion in men independently of melatonin.
Topics: Adult; Darkness; Humans; Light; Luteinizing Hormone; Male; Melatonin; Sleep Deprivation | 1991 |
Altered waveform of plasma nocturnal melatonin secretion in premenstrual depression.
Topics: Adult; Circadian Rhythm; Estradiol; Female; Humans; Melatonin; Menstrual Cycle; Personality Inventor | 1990 |
Influence of melatonin on the sleep-independent component of prolactin secretion.
Topics: Adult; Analysis of Variance; Circadian Rhythm; Female; Humans; Light; Luteinizing Hormone; Melatonin | 1990 |
REM sleep deprivation increases early morning pineal melatonin in castrated rats.
Topics: Animals; Arousal; Male; Melatonin; Pineal Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Sleep | 1989 |
The effect of total sleep deprivation on plasma melatonin and cortisol in healthy human volunteers.
Topics: Adolescent; Adult; Circadian Rhythm; Female; Humans; Hydrocortisone; Male; Melatonin; Sleep Deprivat | 1988 |
Lack of an acute modulatory effect of melatonin on human nocturnal thyrotropin and cortisol secretion.
Topics: Adult; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; Sleep Deprivation; Thyrotropin | 1988 |
Endogenous sleep-substances and sleep regulation.
Topics: Animals; Homeostasis; Humans; Melatonin; Sleep; Sleep Deprivation; Sleep, REM | 1986 |
A model for the study of the acute effects of melatonin in man.
Topics: Adult; Growth Hormone; Humans; Infusions, Intravenous; Male; Melatonin; Prolactin; Sleep; Sleep Depr | 1987 |