Page last updated: 2024-10-19

melatonin and Hypomenorrhea

melatonin has been researched along with Hypomenorrhea in 10 studies

Research Excerpts

ExcerptRelevanceReference
"Melatonin excretion was further decreased during headache."1.29Urinary melatonin excretion throughout the ovarian cycle in menstrually related migraine. ( Costelli, P; Fanciullacci, M; Fonzi, S; Marabini, S; Murialdo, G; Parodi, C; Polleri, A; Solinas, GP, 1994)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's6 (60.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ansari, M1
Karkhaneh, A1
Kheirollahi, A1
Emamgholipour, S1
Rafiee, MH1
Peres, MF1
Zukerman, E1
da Cunha Tanuri, F1
Moreira, FR1
Cipolla-Neto, J1
Barron, ML1
Murialdo, G1
Fonzi, S1
Costelli, P1
Solinas, GP1
Parodi, C1
Marabini, S1
Fanciullacci, M1
Polleri, A1
Díaz, B1
García, R1
Colmenero, MD1
Terrados, N1
Fernández, B1
Marín, B1
Grishchenko, VI1
Parashchuk, IuS1
Shcherbina, NA1
Miyauchi, F3
Nanjo, K3
Otsuka, K3
Buvat, J1
Buvat-Herbaut, M1
Nakamura, Y1
Numa, F1
Kato, H1
Sasaki, T1
Yonezawa, M1
Tsukada, Y1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches[NCT00391755]Phase 44 participants (Actual)Interventional2006-10-31Terminated (stopped due to Failure to recruit necessary number of patients.)
Melatonin for Migraine Prevention (The MMP-study): A Randomized, Double-blind, Cross-over, Placebo-controlled Study of Melatonin in Prophylactic Treatment of Migraine[NCT00849511]Phase 248 participants (Actual)Interventional2009-02-28Completed
"Melatonin for Migraine Prevention in Adolescents: A Pilot Remote Trial: The BRAiN-M Study"[NCT02344316]Phase 231 participants (Actual)Interventional2015-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Headache Diary Compliance Rate

Number of participants that had ≥85% headache diary compliance during weeks 12-16 of the study. (NCT02344316)
Timeframe: Weeks 12-16 of the study

InterventionParticipants (Count of Participants)
Melatonin11
Placebo10

Medication Adherence as Measured by Number of Openings Per Participant

eCAP tack caps will be used to measure medication adherence and the number of openings will be recorded per participant. (NCT02344316)
Timeframe: "during the At Home Active Study Period or Weeks 5-16"

InterventionMean Number of Openings (Mean)
Melatonin39
Placebo60

Number of Migraine/Migrainous Days Per 28 Day Period

Number of Migraine/Migrainous Days Per 28 Day Period in melatonin group and placebo group as measured using an online/mobile device headache diary. (NCT02344316)
Timeframe: final 4 weeks of treatment

Interventiondays (Mean)
Melatonin3.6
Placebo4.9

Number of Minutes to Sleep Onset

Number of minutes to sleep onset as measured by a FitBit. (NCT02344316)
Timeframe: 16 weeks

Interventionminutes (Mean)
Melatonin15.2
Placebo17.2

Reviews

2 reviews available for melatonin and Hypomenorrhea

ArticleYear
Light exposure, melatonin secretion, and menstrual cycle parameters: an integrative review.
    Biological research for nursing, 2007, Volume: 9, Issue:1

    Topics: Chronobiology Disorders; Circadian Rhythm; Clinical Nursing Research; Depression; Female; Follicle S

2007
[Ovulation disturbances in athletes and their mechanisms].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1991, Volume: 20, Issue:7

    Topics: Catecholamines; Corticotropin-Releasing Hormone; Endorphins; Female; Humans; Hydrocortisone; Melaton

1991

Trials

1 trial available for melatonin and Hypomenorrhea

ArticleYear
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004
Melatonin, 3 mg, is effective for migraine prevention.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adult; Alopecia; Analgesics; Disorders of Excessive Somnolence; Female; Humans; Libido; Male; Melato

2004

Other Studies

7 other studies available for melatonin and Hypomenorrhea

ArticleYear
The effect of melatonin on gene expression of calcitonin gene-related peptide and some proinflammatory mediators in patients with pure menstrual migraine.
    Acta neurologica Belgica, 2017, Volume: 117, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Calcitonin Gene-Related Peptide; Cells, Cultured; Female; Gene Expr

2017
Urinary melatonin excretion throughout the ovarian cycle in menstrually related migraine.
    Cephalalgia : an international journal of headache, 1994, Volume: 14, Issue:3

    Topics: Adult; Circadian Rhythm; Female; Humans; Luteal Phase; Melatonin; Menstrual Cycle; Menstruation Dist

1994
Melatonin and gonadotropin hormones in pubertal sportsgirls.
    Revista espanola de fisiologia, 1993, Volume: 49, Issue:1

    Topics: Adolescent; Anthropometry; Exercise Test; Female; Follicle Stimulating Hormone; Humans; Luteinizing

1993
[Role of melatonin in the pathogenesis of dysfunctional uterine bleeding].
    Akusherstvo i ginekologiia, 1977, Issue:12

    Topics: Adolescent; Adult; Female; Humans; Melatonin; Menstruation; Menstruation Disturbances; Pineal Gland;

1977
[Effects of night shift on plasma concentrations of melatonin, LH, FSH and prolactin, and menstrual irregularity].
    Sangyo igaku. Japanese journal of industrial health, 1992, Volume: 34, Issue:6

    Topics: Adult; Circadian Rhythm; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Melatoni

1992
[Effects of continuous lighting on secretion of melatonin and pituitary hormones in women].
    Nihon Sanka Fujinka Gakkai zasshi, 1991, Volume: 43, Issue:5

    Topics: Adult; Female; Follicle Stimulating Hormone; Humans; Lighting; Luteinizing Hormone; Melatonin; Menst

1991
[Clinical significance of measurement of plasma melatonin concentration in women with irregular menstrual cycles].
    Nihon Sanka Fujinka Gakkai zasshi, 1990, Volume: 42, Issue:10

    Topics: Circadian Rhythm; Female; Humans; Melatonin; Menstrual Cycle; Menstruation Disturbances

1990