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melatonin and Hypertrophy

melatonin has been researched along with Hypertrophy in 26 studies

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"We investigated whether melatonin was able to prevent left ventricular hypertrophy (LVH) and fibrosis associated with N(G)-nitro-L-arginine-methyl ester (L-NAME)-induced hypertension."7.75Melatonin prevents fibrosis but not hypertrophy development in the left ventricle of NG-nitro-L-arginine-methyl ester hypertensive rats. ( Adamcova, M; Barta, A; Krajcirovicova, K; Paulis, L; Pechanova, O; Pelouch, V; Simko, F; Zicha, J, 2009)
"The roles of photoperiod, melatonin, and the pineal gland in regulating the magnitude of compensatory gonadal hypertrophy (CGH) and other reproductive and non-reproductive organ growth during post-weaning development were examined in the marsh rice rat Oryzomys palustris."7.73Effects of photoperiod, melatonin, and the pineal gland on compensatory gonadal hypertrophy during postnatal development in the marsh rice rat (Oryzomys palustris). ( Edmonds, K; Masden, T; Riggs, L, 2005)
"In earlier studies from other laboratories it was shown that melatonin decreased ovarian weight in rats and inhibited compensatory hypertrophy of the remaining ovary after unilateral ovariectomy."7.68Effects of pinealectomy and melatonin administration on certain indices of ovarian hyperplasia and/or hypertrophy in rats with both ovaries intact or after unilateral ovariectomy. ( Lewiński, A; Sewerynek, E; Szymczykiewicz, P; Wajs, E, 1993)
"Adult male Syrian hamsters either placed in a short photoperiod alone or kept in a long photoperiod and given daily afternoon injections of the pineal indole melatonin (25 micrograms) exhibited splenic hypertrophy and extramedullary hematopoiesis in addition to a marked regression in testicular weight."7.67Splenic hypertrophy and extramedullary hematopoiesis induced in male Syrian hamsters by short photoperiod or melatonin injections and reversed by melatonin pellets or pinealectomy. ( Champney, TH; Hubbard, GB; Little, JC; Reiter, RJ; Vaughan, GM; Vaughan, MK, 1987)
"Melatonin has been reported to play crucial roles in regulating meat quality, improving reproductive properties, and maintaining intestinal health in animal production, but whether it regulates skeletal muscle development in weaned piglet is rarely studied."7.30Melatonin supplementation promotes muscle fiber hypertrophy and regulates lipid metabolism of skeletal muscle in weaned piglets. ( Cai, P; Chen, W; Gu, X; Huang, Y; Liu, S; Shan, T; Tu, Y; Wang, L; Yi, W; Zhang, S; Zhou, Y, 2023)
"Hypertrophy is a critical process for chondrocyte differentiation and maturation during endochondral ossification, which is responsible for the formation of long bone and postnatal longitudinal growth."5.62Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/β-catenin signaling pathway : Melatonin promotes MSC-derived chondrocytes hypertrophy. ( He, L; He, T; Liu, Z; Pang, M; Rong, L; Wang, X; Xie, P; Yang, B; Zhang, L, 2021)
"We investigated whether melatonin was able to prevent left ventricular hypertrophy (LVH) and fibrosis associated with N(G)-nitro-L-arginine-methyl ester (L-NAME)-induced hypertension."3.75Melatonin prevents fibrosis but not hypertrophy development in the left ventricle of NG-nitro-L-arginine-methyl ester hypertensive rats. ( Adamcova, M; Barta, A; Krajcirovicova, K; Paulis, L; Pechanova, O; Pelouch, V; Simko, F; Zicha, J, 2009)
"Adult male Syrian hamsters either placed in a short photoperiod alone or kept in a long photoperiod and given daily afternoon injections of the pineal indole melatonin (25 micrograms) exhibited splenic hypertrophy and extramedullary hematopoiesis in addition to a marked regression in testicular weight."3.67Splenic hypertrophy and extramedullary hematopoiesis induced in male Syrian hamsters by short photoperiod or melatonin injections and reversed by melatonin pellets or pinealectomy. ( Champney, TH; Hubbard, GB; Little, JC; Reiter, RJ; Vaughan, GM; Vaughan, MK, 1987)
"The increase of brain serotonin level following the treatment of hemicastrate adult female rats with L-tryptophane or Agr-1240 inhibits the compensatory ovarian hypertrophy (COH)."3.66Study on serotoninergic mechanisms of compensatory ovarian hypertrophy in rats. ( Anisimov, VN, 1980)
"Melatonin has been reported to play crucial roles in regulating meat quality, improving reproductive properties, and maintaining intestinal health in animal production, but whether it regulates skeletal muscle development in weaned piglet is rarely studied."3.30Melatonin supplementation promotes muscle fiber hypertrophy and regulates lipid metabolism of skeletal muscle in weaned piglets. ( Cai, P; Chen, W; Gu, X; Huang, Y; Liu, S; Shan, T; Tu, Y; Wang, L; Yi, W; Zhang, S; Zhou, Y, 2023)
"Melatonin treatment for 8 weeks resulted in a significant increase (P < 0."1.29Effect of long-term administration of melatonin on adrenal histomorphology of the Indian desert gerbil Meriones hurrianae Jerdon. ( Joshi, BN; Sujathakumari, M, 1995)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199015 (57.69)18.7374
1990's5 (19.23)18.2507
2000's4 (15.38)29.6817
2010's0 (0.00)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Chen, W1
Tu, Y1
Cai, P1
Wang, L1
Zhou, Y1
Liu, S1
Huang, Y1
Zhang, S1
Gu, X1
Yi, W1
Shan, T1
Wang, X1
He, T1
He, L1
Yang, B1
Liu, Z1
Pang, M1
Xie, P1
Zhang, L1
Rong, L1
Paulis, L1
Pechanova, O1
Zicha, J1
Krajcirovicova, K1
Barta, A1
Pelouch, V1
Adamcova, M1
Simko, F1
Edmonds, K1
Riggs, L1
Masden, T1
Quiroz, Y1
Ferrebuz, A1
Romero, F1
Vaziri, ND1
Rodriguez-Iturbe, B1
Vriend, J1
Anisimov, VN1
Bhagat, L1
Duraiswami, S1
Muralidhar, K1
Lewiński, A1
Szymczykiewicz, P1
Sewerynek, E1
Wajs, E1
Joshi, BN1
Sujathakumari, M1
Oishi, T1
Mohri, Y1
Kaneko, T1
Sasaki, M1
Hattori, A1
Obara, Y1
Masuda, A1
Mayer, I1
Bornestaf, C1
Wetterberg, L1
Borg, B1
Djeridane, Y1
Pitrosky, B1
Vivien-Roels, B1
Simonneaux, V1
Kirsch, R1
Pévet, P1
Benson, B6
Little, JC2
Vaughan, MK5
Hubbard, GB1
Champney, TH1
Vaughan, GM5
Reiter, RJ4
Orts, RJ1
Cook, BF1
Fraschini, F1
Mess, B1
Martini, L1
Bigelow, L1
Altschule, MD1
Matthews, MJ2
Rodin, AE2
Norris, JT1
Rubin, BD1
Traum, RE1
Singh, DV1
Narang, GD1
Turner, CW1

Reviews

2 reviews available for melatonin and Hypertrophy

ArticleYear
Evidence for pineal gland modulation of the neuroendocrine-thyroid axis.
    Neuroendocrinology, 1983, Volume: 36, Issue:1

    Topics: Animals; Cricetinae; Hypertrophy; Melatonin; Mesocricetus; Mice; Pineal Gland; Rats; Thyroid Gland;

1983
Current status of pineal peptides.
    Neuroendocrinology, 1977, Volume: 24, Issue:3-4

    Topics: Animals; Female; Fertility; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Hypert

1977

Trials

1 trial available for melatonin and Hypertrophy

ArticleYear
Melatonin supplementation promotes muscle fiber hypertrophy and regulates lipid metabolism of skeletal muscle in weaned piglets.
    Journal of animal science, 2023, Jan-03, Volume: 101

    Topics: Animals; Dietary Supplements; Hypertrophy; Lipid Metabolism; Melatonin; Muscle Fibers, Skeletal; Mus

2023

Other Studies

23 other studies available for melatonin and Hypertrophy

ArticleYear
Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/β-catenin signaling pathway : Melatonin promotes MSC-derived chondrocytes hypertrophy.
    Stem cell research & therapy, 2021, 08-21, Volume: 12, Issue:1

    Topics: Cell Differentiation; Cells, Cultured; Chondrocytes; Chondrogenesis; Hedgehog Proteins; Humans; Hype

2021
Melatonin prevents fibrosis but not hypertrophy development in the left ventricle of NG-nitro-L-arginine-methyl ester hypertensive rats.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2009, Volume: 27, Issue:6

    Topics: Animals; Blood Pressure; Fibrosis; Free Radical Scavengers; Heart Ventricles; Hemodynamics; Hydroxyp

2009
Effects of photoperiod, melatonin, and the pineal gland on compensatory gonadal hypertrophy during postnatal development in the marsh rice rat (Oryzomys palustris).
    Zoological science, 2005, Volume: 22, Issue:7

    Topics: Animals; Female; Hypertrophy; Male; Melatonin; Ovary; Photoperiod; Pineal Gland; Reproduction; Sigmo

2005
Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2

    Topics: Actins; Animals; Blood Pressure; Cell Movement; Collagen Type IV; Creatinine; Disease Models, Animal

2008
Study on serotoninergic mechanisms of compensatory ovarian hypertrophy in rats.
    Endokrinologie, 1980, Volume: 75, Issue:2

    Topics: Animals; Brain; Castration; Diethylstilbestrol; Female; Hypertrophy; Indoles; Levodopa; Melatonin; M

1980
Mode of action of inhibin-like pineal antigonadotropin is different from melatonin during compensatory ovarian hypertrophy.
    Journal of pineal research, 1994, Volume: 16, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Hypertrophy; Inhibi

1994
Effects of pinealectomy and melatonin administration on certain indices of ovarian hyperplasia and/or hypertrophy in rats with both ovaries intact or after unilateral ovariectomy.
    Journal of pineal research, 1993, Volume: 14, Issue:3

    Topics: Animals; Corpus Luteum; Female; Granulosa Cells; Hyperplasia; Hypertrophy; Melatonin; Mitosis; Organ

1993
Effect of long-term administration of melatonin on adrenal histomorphology of the Indian desert gerbil Meriones hurrianae Jerdon.
    Indian journal of experimental biology, 1995, Volume: 33, Issue:11

    Topics: Adrenal Glands; Animals; Drug Administration Schedule; Female; Gerbillinae; Hypertrophy; Male; Melat

1995
Retinal melatonin is not involved in corneal mitotic rhythms in the Japanese quail: effects of formoguanamine hydrochloride and eye-lid suture.
    Journal of pineal research, 1996, Volume: 21, Issue:3

    Topics: Animals; Circadian Rhythm; Cornea; Coturnix; Dark Adaptation; Epithelial Cells; Epithelium; Eye; Eye

1996
Melatonin does not prevent long photoperiod stimulation of secondary sexual characters in the male three-spined stickleback Gasterosteus aculeatus.
    General and comparative endocrinology, 1997, Volume: 108, Issue:3

    Topics: Animals; Female; Fishes; Hypertrophy; Kidney; Light; Male; Melatonin; Photoperiod; Spermatogenesis

1997
Long-term daily melatonin infusion induces a large increase in N-acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin content in the Harderian gland and eye of pinealectomized male Siberian hamsters (Phodopus sungorus).
    Journal of pineal research, 2000, Volume: 29, Issue:2

    Topics: Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Crice

2000
Alteration of compensatory ovarian hypertrophy in the hamster by melatonin.
    Life sciences, 1978, Jun-26, Volume: 22, Issue:24

    Topics: Animals; Castration; Cricetinae; Estrus; Female; Functional Laterality; Hypertrophy; Melatonin; Meso

1978
Splenic hypertrophy and extramedullary hematopoiesis induced in male Syrian hamsters by short photoperiod or melatonin injections and reversed by melatonin pellets or pinealectomy.
    The American journal of anatomy, 1987, Volume: 179, Issue:2

    Topics: Animals; Cricetinae; Drug Implants; Female; Hematopoiesis; Hypertrophy; Injections; Light; Male; Mel

1987
Melatonin action on the time course of compensatory ovarian hypertrophy in the Swiss-Webster mouse.
    International journal of fertility, 1972, Volume: 17, Issue:1

    Topics: Animals; Castration; Depression, Chemical; Female; Hypertrophy; Injections; Melatonin; Mice; Organ S

1972
Some antigonadotrophic effects of melatonin-free bovine pineal extracts in rats.
    Acta endocrinologica, 1974, Volume: 76, Issue:3

    Topics: Animals; Castration; Cattle; Chromatography, Gel; Depression, Chemical; Estrus; Female; Hypertrophy;

1974
Pineal gland, melatonin and the control of luteinizing hormone secretion.
    Endocrinology, 1968, Volume: 82, Issue:5

    Topics: Adrenal Glands; Animals; Castration; Hypertrophy; Hypothalamo-Hypophyseal System; Luteinizing Hormon

1968
Inhibition of compensatory ovarian hypertrophy in the mouse and vole: a comparison of Altschule's pineal extract, pineal indoles, vasopressin, and oxytocin.
    General and comparative endocrinology, 1972, Volume: 18, Issue:2

    Topics: Animals; Castration; Disease Models, Animal; Drug Antagonism; Female; Follicle Stimulating Hormone;

1972
A melatonin-free extract of bovine pineal with antigonadotropic activity.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Jun-01, Volume: 10, Issue:11

    Topics: Animals; Castration; Cattle; Chromatography, Gel; Female; Gonadotropins; Hypertrophy; Melatonin; Mic

1971
Inhibition of compensatory ovarian hypertrophy in mice by melatonin, 5-hydroxytryptamine and pineal powder.
    The Journal of endocrinology, 1971, Volume: 50, Issue:1

    Topics: Animals; Castration; Estrus; Female; Hypertrophy; Melatonin; Mice; Ovary; Pineal Gland; Pregnancy; S

1971
Effect of delaying melatonin injections on the inhibition of compensatory ovarian hypertrophy in mice.
    The Journal of endocrinology, 1971, Volume: 51, Issue:4

    Topics: Animals; Castration; Depression, Chemical; Feedback; Female; Hypertrophy; Hypothalamus; Injections,

1971
Antigonadotropic activity in a melatonin-free extract of human pineal glands.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Cerebral Cortex; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Hypertrophy;

1971
The effect of melatonin on ovarian compensatory hypertrophy in the rat.
    The Journal of endocrinology, 1971, Volume: 50, Issue:1

    Topics: Adrenal Glands; Animals; Castration; Female; Hypertrophy; Melatonin; Organ Size; Ovary; Pituitary Gl

1971
Effect of melatonin and its withdrawal on thyroid hormone secretion rate of female rats.
    The Journal of endocrinology, 1969, Volume: 43, Issue:3

    Topics: Age Factors; Animals; Female; Hyperplasia; Hypertrophy; Melatonin; Rats; Thyroid Gland; Thyroid Horm

1969