Page last updated: 2024-10-19

melatonin and Hyperplasia

melatonin has been researched along with Hyperplasia in 11 studies

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"Melatonin is a hormone produced by the pineal gland with increased circulating levels shown to inhibit biliary hyperplasia and fibrosis during cholestatic liver injury."7.85Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats. ( Alpini, G; DeMorrow, S; Giang, T; Glaser, S; Grant, S; Greene, JF; Jefferson, B; Kyritsi, K; McMillin, M; Meng, F; Venter, J; Wu, N; Zhou, T, 2017)
"In earlier studies from other laboratories it was shown that melatonin decreased ovarian weight in rats and inhibited compensatory hypertrophy of the remaining ovary after unilateral ovariectomy."7.68Effects of pinealectomy and melatonin administration on certain indices of ovarian hyperplasia and/or hypertrophy in rats with both ovaries intact or after unilateral ovariectomy. ( Lewiński, A; Sewerynek, E; Szymczykiewicz, P; Wajs, E, 1993)
"Melatonin treatment led to a significant reduction in the degree of breast hyperplasia (P<0."5.62Melatonin inhibits cell proliferation in a rat model of breast hyperplasia by mediating the PTEN/AKT pathway. ( Huang, Y; Niu, Y; Zhang, X, 2021)
"Melatonin is a hormone produced by the pineal gland with increased circulating levels shown to inhibit biliary hyperplasia and fibrosis during cholestatic liver injury."3.85Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats. ( Alpini, G; DeMorrow, S; Giang, T; Glaser, S; Grant, S; Greene, JF; Jefferson, B; Kyritsi, K; McMillin, M; Meng, F; Venter, J; Wu, N; Zhou, T, 2017)
" We investigated the effect of melatonin on the development of urothelial hyperplasia induced by repeated CP treatment."3.75Melatonin prevents the development of hyperplastic urothelium induced by repeated doses of cyclophosphamide. ( Jezernik, K; Vidmar, G; Zupancic, D, 2009)
"Melatonin treatment led to a significant reduction in the degree of breast hyperplasia (P<0."1.62Melatonin inhibits cell proliferation in a rat model of breast hyperplasia by mediating the PTEN/AKT pathway. ( Huang, Y; Niu, Y; Zhang, X, 2021)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's3 (27.27)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Victor, S1
Rocha-Ferreira, E1
Rahim, A1
Hagberg, H1
Edwards, D1
Wang, X1
Li, T1
Ma, B1
Zhao, Z1
Ni, L1
Zhang, R1
Niu, S1
Liu, C1
Zhang, X1
Niu, Y1
Huang, Y1
McMillin, M1
DeMorrow, S3
Glaser, S3
Venter, J3
Kyritsi, K1
Zhou, T1
Grant, S1
Giang, T1
Greene, JF1
Wu, N1
Jefferson, B1
Meng, F3
Alpini, G3
Han, Y2
Onori, P2
Francis, H2
Franchitto, A2
Ray, D1
Kennedy, L1
Greene, J1
Renzi, A2
Mancinelli, R2
Gaudio, E2
Ozen, H1
Karaman, M1
Ciğremiş, Y1
Tuzcu, M1
Ozcan, K1
Erdağ, D1
Zupancic, D1
Vidmar, G1
Jezernik, K1
White, M1
Alvaro, D1
Carpino, G1
Ueno, Y1
Lewiński, A1
Szymczykiewicz, P1
Sewerynek, E1
Wajs, E1
Raĭkhlin, NT1
Kvetnoĭ, IM1
Singh, DV1
Narang, GD1
Turner, CW1

Reviews

1 review available for melatonin and Hyperplasia

ArticleYear
New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy.
    European journal of pediatrics, 2022, Volume: 181, Issue:3

    Topics: Animals; Humans; Hyperplasia; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Melatonin; Neuroprotect

2022

Other Studies

10 other studies available for melatonin and Hyperplasia

ArticleYear
Melatonin attenuates restenosis after vascular injury in diabetic rats through activation of the Nrf2 signaling pathway.
    Biochemical and biophysical research communications, 2021, 04-09, Volume: 548

    Topics: Animals; Carotid Arteries; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Restenosis;

2021
Melatonin inhibits cell proliferation in a rat model of breast hyperplasia by mediating the PTEN/AKT pathway.
    Oncology reports, 2021, Volume: 45, Issue:5

    Topics: Animals; Cell Proliferation; Disease Models, Animal; Female; Hyperplasia; Immunohistochemistry; Mamm

2021
Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2017, Nov-01, Volume: 313, Issue:5

    Topics: Animals; Bile Ducts; Cell Proliferation; Central Nervous System Depressants; Cholestasis; Disease Mo

2017
Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Nov-01, Volume: 307, Issue:9

    Topics: Animals; ARNTL Transcription Factors; Arylalkylamine N-Acetyltransferase; Bile Acids and Salts; Bile

2014
Effectiveness of melatonin on aflatoxicosis in chicks.
    Research in veterinary science, 2009, Volume: 86, Issue:3

    Topics: Aflatoxins; Animals; Antioxidants; Antitoxins; Apoptosis; Aspergillosis; Bile Ducts; Cell Death; Chi

2009
Melatonin prevents the development of hyperplastic urothelium induced by repeated doses of cyclophosphamide.
    Virchows Archiv : an international journal of pathology, 2009, Volume: 454, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Cell Proliferation; Cy

2009
Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:4

    Topics: Animals; ARNTL Transcription Factors; Bicarbonates; Bile Ducts; Cell Proliferation; Cholestasis; CLO

2011
Effects of pinealectomy and melatonin administration on certain indices of ovarian hyperplasia and/or hypertrophy in rats with both ovaries intact or after unilateral ovariectomy.
    Journal of pineal research, 1993, Volume: 14, Issue:3

    Topics: Animals; Corpus Luteum; Female; Granulosa Cells; Hyperplasia; Hypertrophy; Melatonin; Mitosis; Organ

1993
[Dynamics of changes in enterochromaffin cells during tumor growth].
    Voprosy onkologii, 1976, Volume: 22, Issue:1

    Topics: Chromaffin System; Enterochromaffin Cells; Gastrointestinal Neoplasms; Humans; Hyperplasia; Leukemia

1976
Effect of melatonin and its withdrawal on thyroid hormone secretion rate of female rats.
    The Journal of endocrinology, 1969, Volume: 43, Issue:3

    Topics: Age Factors; Animals; Female; Hyperplasia; Hypertrophy; Melatonin; Rats; Thyroid Gland; Thyroid Horm

1969