Page last updated: 2024-10-19

melatonin and Glucose Intolerance

melatonin has been researched along with Glucose Intolerance in 10 studies

Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.

Research Excerpts

ExcerptRelevanceReference
"The present results indicate that in aged women administration of 1 mg of melatonin reduces glucose tolerance and insulin sensitivity."9.09Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women. ( Arangino, S; Cagnacci, A; Cagnacci, P; Melis, GB; Paoletti, AM; Renzi, A; Volpe, A, 2001)
"The aim: To determine the influence of melatonin on the glucose level and content of malondialdehyde, activities of pyruvate kinase and glucose-6-phosphate dehydrogenase enzymes in the blood; histochemical features of glycogen distribution in liver of rats with impaired glucose tolerance."8.31CARBOHYDRATES METABOLISM IN THE BLOOD OF RATS WITH IMPAIRED GLUCOSE TOLERANCE UNDER LONG TERM MELATONIN INJECTIONS. ( Kushnir, OY; Pantsiuk, KA; Tymkul, DM; Vivsyannuk, VV; Vlasova, KV; Vlasova, OV; Yaremii, IM, 2023)
"Excess weight and obesity are severe public health threats worldwide."5.46Melatonin prevents obesity through modulation of gut microbiota in mice. ( Hong, F; Jia, L; Jin, X; Wang, J; Wang, S; Xu, P; Xue, T; Zhai, Y, 2017)
"Melatonin treatment alone improved circadian activity rhythms, attenuated induction of β-cell failure, and enhanced glucose tolerance."5.43Administration of Melatonin and Metformin Prevents Deleterious Effects of Circadian Disruption and Obesity in Male Rats. ( Hoang, J; Matveyenko, AV; Nguyen, A; Rakshit, K; Thomas, AP; Vongbunyong, K, 2016)
"Melatonin administration impaired glucose tolerance."5.19Acute melatonin administration in humans impairs glucose tolerance in both the morning and evening. ( Garaulet, M; Gómez-Abellán, P; Madrid, JA; Rubio-Sastre, P; Scheer, FA, 2014)
"The present results indicate that in aged women administration of 1 mg of melatonin reduces glucose tolerance and insulin sensitivity."5.09Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women. ( Arangino, S; Cagnacci, A; Cagnacci, P; Melis, GB; Paoletti, AM; Renzi, A; Volpe, A, 2001)
"The aim: To determine the influence of melatonin on the glucose level and content of malondialdehyde, activities of pyruvate kinase and glucose-6-phosphate dehydrogenase enzymes in the blood; histochemical features of glycogen distribution in liver of rats with impaired glucose tolerance."4.31CARBOHYDRATES METABOLISM IN THE BLOOD OF RATS WITH IMPAIRED GLUCOSE TOLERANCE UNDER LONG TERM MELATONIN INJECTIONS. ( Kushnir, OY; Pantsiuk, KA; Tymkul, DM; Vivsyannuk, VV; Vlasova, KV; Vlasova, OV; Yaremii, IM, 2023)
"Several novel animal studies have shown that intrauterine metabolic programming can be modified in the event of reduced melatonin synthesis during pregnancy, leading to glucose intolerance and insulin resistance in the offspring."3.91Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring. ( Amaral, F; Cipolla-Neto, J; Lowden, A; Moreno, CRC; Nehme, PA; Skene, DJ, 2019)
" LPF, but not DPF rats, exhibited increased hypothalamic AMPK phosphorylation, glucose intolerance, reduced urinary 6-sulfatoxymelatonin (6-S-Mel) (a metabolite of melatonin) and increased corticosterone levels."3.85Metabolic Impact of Light Phase-Restricted Fructose Consumption Is Linked to Changes in Hypothalamic AMPK Phosphorylation and Melatonin Production in Rats. ( Anhê, GF; Bordin, S; de Araújo, TM; Faria, JA; Ignácio-Souza, LM; Razolli, DS; Souza, DN, 2017)
"Excess weight and obesity are severe public health threats worldwide."1.46Melatonin prevents obesity through modulation of gut microbiota in mice. ( Hong, F; Jia, L; Jin, X; Wang, J; Wang, S; Xu, P; Xue, T; Zhai, Y, 2017)
"Melatonin treatment alone improved circadian activity rhythms, attenuated induction of β-cell failure, and enhanced glucose tolerance."1.43Administration of Melatonin and Metformin Prevents Deleterious Effects of Circadian Disruption and Obesity in Male Rats. ( Hoang, J; Matveyenko, AV; Nguyen, A; Rakshit, K; Thomas, AP; Vongbunyong, K, 2016)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Zeng, Y1
Zhang, Z1
Liang, S1
Chang, X1
Qin, R1
Chen, H1
Guo, L1
Kushnir, OY1
Yaremii, IM1
Pantsiuk, KA1
Vivsyannuk, VV1
Tymkul, DM1
Vlasova, KV1
Vlasova, OV1
Nehme, PA1
Amaral, F1
Lowden, A1
Skene, DJ1
Cipolla-Neto, J1
Moreno, CRC1
Lopez-Minguez, J1
Gómez-Abellán, P2
Garaulet, M2
Faria, JA1
de Araújo, TM1
Razolli, DS1
Ignácio-Souza, LM1
Souza, DN1
Bordin, S1
Anhê, GF1
Rubio-Sastre, P1
Scheer, FA1
Madrid, JA1
Thomas, AP1
Hoang, J1
Vongbunyong, K1
Nguyen, A1
Rakshit, K1
Matveyenko, AV1
Mendez, N1
Halabi, D1
Spichiger, C1
Salazar, ER1
Vergara, K1
Alonso-Vasquez, P1
Carmona, P1
Sarmiento, JM1
Richter, HG1
Seron-Ferre, M1
Torres-Farfan, C1
Xu, P1
Wang, J1
Hong, F1
Wang, S1
Jin, X1
Xue, T1
Jia, L1
Zhai, Y1
Cagnacci, A1
Arangino, S1
Renzi, A1
Paoletti, AM1
Melis, GB1
Cagnacci, P1
Volpe, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of the Administration of Melatonin and Metformin on Glycemic Control, Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes: Pilot Study[NCT03848533]Phase 242 participants (Anticipated)Interventional2019-08-22Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for melatonin and Glucose Intolerance

ArticleYear
Timing of Breakfast, Lunch, and Dinner. Effects on Obesity and Metabolic Risk.
    Nutrients, 2019, Nov-01, Volume: 11, Issue:11

    Topics: Adipose Tissue; Animals; Blood Glucose; Breakfast; Circadian Rhythm; Feeding Behavior; Female; Gluco

2019

Trials

2 trials available for melatonin and Glucose Intolerance

ArticleYear
Acute melatonin administration in humans impairs glucose tolerance in both the morning and evening.
    Sleep, 2014, Oct-01, Volume: 37, Issue:10

    Topics: Adult; Area Under Curve; Blood Glucose; Body Mass Index; Female; Glucose Intolerance; Glucose Tolera

2014
Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women.
    Clinical endocrinology, 2001, Volume: 54, Issue:3

    Topics: Analysis of Variance; Area Under Curve; Blood Glucose; C-Peptide; Estradiol; Estrogen Replacement Th

2001

Other Studies

7 other studies available for melatonin and Glucose Intolerance

ArticleYear
Paternal sleep deprivation induces metabolic perturbations in male offspring via altered LRP5 DNA methylation of pancreatic islets.
    Journal of pineal research, 2023, Volume: 74, Issue:4

    Topics: Animals; Cyclin D1; Cyclin D2; Diabetes Mellitus; DNA Methylation; Fathers; Glucose Intolerance; Hum

2023
CARBOHYDRATES METABOLISM IN THE BLOOD OF RATS WITH IMPAIRED GLUCOSE TOLERANCE UNDER LONG TERM MELATONIN INJECTIONS.
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2023, Volume: 76, Issue:8

    Topics: Animals; Glucose; Glucose Intolerance; Glucosephosphate Dehydrogenase; Glycogen; Melatonin; Pyruvate

2023
Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring.
    Medical hypotheses, 2019, Volume: 132

    Topics: Circadian Rhythm; Energy Metabolism; Female; Fetus; Glucose Intolerance; Humans; Insulin Resistance;

2019
Metabolic Impact of Light Phase-Restricted Fructose Consumption Is Linked to Changes in Hypothalamic AMPK Phosphorylation and Melatonin Production in Rats.
    Nutrients, 2017, Mar-27, Volume: 9, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Circadian Rhythm; Corticosterone; Dose-Response Relationship

2017
Administration of Melatonin and Metformin Prevents Deleterious Effects of Circadian Disruption and Obesity in Male Rats.
    Endocrinology, 2016, Volume: 157, Issue:12

    Topics: Adiposity; Animals; Central Nervous System Depressants; Circadian Rhythm; Glucose Intolerance; Hypog

2016
Gestational Chronodisruption Impairs Circadian Physiology in Rat Male Offspring, Increasing the Risk of Chronic Disease.
    Endocrinology, 2016, Volume: 157, Issue:12

    Topics: Aldosterone; Animals; Blood Pressure; Body Temperature; Chronic Disease; Circadian Rhythm; CLOCK Pro

2016
Melatonin prevents obesity through modulation of gut microbiota in mice.
    Journal of pineal research, 2017, Volume: 62, Issue:4

    Topics: Animals; Bacteroidetes; Blotting, Western; Central Nervous System Depressants; Diet, High-Fat; Fatty

2017