Page last updated: 2024-10-19

melatonin and Genome Instability

melatonin has been researched along with Genome Instability in 6 studies

Research Excerpts

ExcerptRelevanceReference
"Evidence suggests that genomic instability is responsible for cancer incidence after exposure to carcinogenic agents, and increases the risk of secondary cancers following treatment with radiotherapy or chemotherapy."2.61Melatonin and cancer: From the promotion of genomic stability to use in cancer treatment. ( Farhood, B; Goradel, NH; Khanlarkhani, N; Mortezaee, K; Najafi, M; Sahebkar, A, 2019)
"Melatonin is a natural indoleamine produced by the pineal gland that has many functions, including regulation of the circadian rhythm."2.58Melatonin and Cancer Hallmarks. ( Talib, WH, 2018)
"While the emphasis of melatonin/cancer research has been on the role of the indoleamine in restraining breast cancer, this is changing quickly with many cancer types having been shown to be susceptible to inhibition by melatonin."2.55Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis. ( Acuna-Castroviejo, D; Qin, L; Reiter, RJ; Rosales-Corral, SA; Tan, DX; Xu, K; Yang, SF, 2017)
"Relative to genomic instability, melatonin was effective in reducing DNA damage caused by ageing, presenting antigenotoxic and antimutagenic activities, independently of initiation age."1.56Melatonin supplementation over different time periods until ageing modulates genotoxic parameters in mice. ( Damiani, AP; de Andrade, VM; de Oliveira Sardinha, TT; de Pinho, RA; Gajski, G; Rohr, P; Strapazzon, G, 2020)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Damiani, AP1
Strapazzon, G1
de Oliveira Sardinha, TT1
Rohr, P1
Gajski, G1
de Pinho, RA1
de Andrade, VM1
Reiter, RJ2
Rosales-Corral, SA1
Tan, DX1
Acuna-Castroviejo, D1
Qin, L1
Yang, SF1
Xu, K1
Talib, WH1
Giudice, A1
Crispo, A1
Grimaldi, M1
Polo, A1
Bimonte, S1
Capunzo, M1
Amore, A1
D'Arena, G1
Cerino, P1
Budillon, A1
Botti, G1
Costantini, S1
Montella, M1
Majidinia, M1
Shakouri, SK1
Yousefi, B1
Farhood, B1
Goradel, NH1
Mortezaee, K1
Khanlarkhani, N1
Najafi, M1
Sahebkar, A1

Reviews

5 reviews available for melatonin and Genome Instability

ArticleYear
Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis.
    International journal of molecular sciences, 2017, Apr-17, Volume: 18, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation,

2017
Melatonin and Cancer Hallmarks.
    Molecules (Basel, Switzerland), 2018, Feb-26, Volume: 23, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Disease Pr

2018
The Effect of Light Exposure at Night (LAN) on Carcinogenesis via Decreased Nocturnal Melatonin Synthesis.
    Molecules (Basel, Switzerland), 2018, May-29, Volume: 23, Issue:6

    Topics: Animals; Biological Clocks; Carcinogenesis; CLOCK Proteins; Energy Metabolism; Gene Expression Regul

2018
The role of melatonin, a multitasking molecule, in retarding the processes of ageing.
    Ageing research reviews, 2018, Volume: 47

    Topics: Aging; Animals; Antioxidants; Brain; Circadian Rhythm; Energy Metabolism; Free Radicals; Genomic Ins

2018
Melatonin and cancer: From the promotion of genomic stability to use in cancer treatment.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Cell Transformation, Neoplast

2019

Other Studies

1 other study available for melatonin and Genome Instability

ArticleYear
Melatonin supplementation over different time periods until ageing modulates genotoxic parameters in mice.
    Mutagenesis, 2020, 12-31, Volume: 35, Issue:6

    Topics: Aging; Animals; Biomarkers; Comet Assay; Dietary Supplements; DNA Damage; Duration of Therapy; Genom

2020