melatonin has been researched along with Fra(X) Syndrome in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the efficacy of melatonin on sleep problems in children with autistic spectrum disorder (ASD) and fragile X syndrome (FXS)." | 9.14 | The efficacy of melatonin for sleep problems in children with autism, fragile X syndrome, or autism and fragile X syndrome. ( Anders, TF; Bacalman, S; Diaz, R; Goodlin-Jones, BL; Hagerman, RJ; Jacquemont, S; Wirojanan, J, 2009) |
| "Fragile X syndrome is the most common form of inherited mental retardation." | 5.35 | Protective effects of melatonin against oxidative stress in Fmr1 knockout mice: a therapeutic research model for the fragile X syndrome. ( de Diego-Otero, Y; de Fonseca, FR; Decara, J; Del Arco-Herrera, I; el Bekay, R; Romero-Zerbo, Y; Sanchez-Salido, L, 2009) |
| "To determine the efficacy of melatonin on sleep problems in children with autistic spectrum disorder (ASD) and fragile X syndrome (FXS)." | 5.14 | The efficacy of melatonin for sleep problems in children with autism, fragile X syndrome, or autism and fragile X syndrome. ( Anders, TF; Bacalman, S; Diaz, R; Goodlin-Jones, BL; Hagerman, RJ; Jacquemont, S; Wirojanan, J, 2009) |
| "Fragile X syndrome is the most common form of inherited mental retardation." | 1.35 | Protective effects of melatonin against oxidative stress in Fmr1 knockout mice: a therapeutic research model for the fragile X syndrome. ( de Diego-Otero, Y; de Fonseca, FR; Decara, J; Del Arco-Herrera, I; el Bekay, R; Romero-Zerbo, Y; Sanchez-Salido, L, 2009) |
| "Melatonin profiles were studied in five males with cytogenetic and clinical features of the fragile-X syndrome including megalo-orchidia and macrogenitosomia." | 1.27 | Does melatonin deficiency cause the enlarged genitalia of the fragile-X syndrome? ( Andrews, H; Arendt, J; Astley, P; Corrall, RJ; O'Brien, IA; O'Hare, JP; Ratcliffe, W; Walters, R, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Won, J | 1 |
| Jin, Y | 1 |
| Choi, J | 1 |
| Park, S | 1 |
| Lee, TH | 1 |
| Lee, SR | 1 |
| Chang, KT | 1 |
| Hong, Y | 1 |
| Romero-Zerbo, Y | 1 |
| Decara, J | 1 |
| el Bekay, R | 1 |
| Sanchez-Salido, L | 1 |
| Del Arco-Herrera, I | 1 |
| de Fonseca, FR | 1 |
| de Diego-Otero, Y | 1 |
| Wirojanan, J | 1 |
| Jacquemont, S | 1 |
| Diaz, R | 1 |
| Bacalman, S | 1 |
| Anders, TF | 1 |
| Hagerman, RJ | 2 |
| Goodlin-Jones, BL | 1 |
| Hagerman, R | 1 |
| Lauterborn, J | 1 |
| Au, J | 1 |
| Berry-Kravis, E | 1 |
| Gould, EL | 1 |
| Loesch, DZ | 1 |
| Martin, MJ | 1 |
| Armstrong, SM | 1 |
| Huggins, RM | 1 |
| O'Hare, JP | 1 |
| O'Brien, IA | 1 |
| Arendt, J | 1 |
| Astley, P | 1 |
| Ratcliffe, W | 1 |
| Andrews, H | 1 |
| Walters, R | 1 |
| Corrall, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Double-blind Randomized Placebo-controlled 1-way Crossover Trial to Investigate Safety and Efficacy of the Ascorbic Acid and Tocopherol for the Treatment of the Fragile X Syndrome[NCT01329770] | Phase 2 | 30 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for melatonin and Fra(X) Syndrome
| Article | Year |
|---|---|
Melatonin as a Novel Interventional Candidate for Fragile X Syndrome with Autism Spectrum Disorder in Humans.
Topics: Anxiety; Autism Spectrum Disorder; Circadian Clocks; Circadian Rhythm; Fragile X Mental Retardation | 2017 |
Fragile X syndrome and targeted treatment trials.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Baclofen; Brain-Derived Neurotrophic Factor; Central N | 2012 |
1 trial available for melatonin and Fra(X) Syndrome
| Article | Year |
|---|---|
The efficacy of melatonin for sleep problems in children with autism, fragile X syndrome, or autism and fragile X syndrome.
Topics: Adolescent; Autistic Disorder; Central Nervous System Depressants; Child; Child, Preschool; Cross-Ov | 2009 |
3 other studies available for melatonin and Fra(X) Syndrome
| Article | Year |
|---|---|
Protective effects of melatonin against oxidative stress in Fmr1 knockout mice: a therapeutic research model for the fragile X syndrome.
Topics: Animals; Antioxidants; Behavior, Animal; Disease Models, Animal; Fragile X Mental Retardation Protei | 2009 |
Melatonin profiles and sleep characteristics in boys with fragile X syndrome: a preliminary study.
Topics: Age Factors; Body Mass Index; Child; Child, Preschool; Fragile X Syndrome; Humans; Male; Melatonin; | 2000 |
Does melatonin deficiency cause the enlarged genitalia of the fragile-X syndrome?
Topics: Aged; Fragile X Syndrome; Genitalia, Male; Humans; Male; Melatonin; Middle Aged; Pedigree; Penis; Se | 1986 |