melatonin has been researched along with Femoral Fractures in 4 studies
Femoral Fractures: Fractures of the femur.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our previous study documented that melatonin (MLT) induced the osteogenic differentiation of mesenchymal stem cells (MSCs) and promoted the healing of femoral fractures in rats via the neuropeptide Y (NPY)/neuropeptide Y1 receptor (NPY1R) signaling pathway." | 3.96 | Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats. ( Dong, P; Gu, X; Ma, B; Shang, J; Wang, C; Zhu, G; Zi, Y, 2020) |
| "Melatonin improves fracture healing, but the long-term use of melatonin seems impracticable in the treatment of fracture due to side effects caused by hormonal stress on chronological rhythm." | 1.56 | Do peripheral melatonin agonists improve bone fracture healing? The effects of agomelatine and ramelteon on experimental bone fracture. ( Aydın, A; Gürbüz, MA; Halıcı, Z; Karaman, A; Köse, A; Köse, D; Toktay, E; Ugan, RA, 2020) |
| "Because bone resorption is an essential requirement for adequate remodeling during fracture healing, we conclude that melatonin impairs fracture healing by suppressing bone resorption through down-regulation of RANKL-mediated osteoclast activation." | 1.38 | Melatonin impairs fracture healing by suppressing RANKL-mediated bone remodeling. ( Anton, C; Garcia, P; Histing, T; Holstein, JH; Klein, M; Matthys, R; Menger, MD; Pohlemann, T; Scheuer, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Köse, D | 1 |
| Köse, A | 1 |
| Halıcı, Z | 1 |
| Gürbüz, MA | 1 |
| Aydın, A | 1 |
| Ugan, RA | 1 |
| Karaman, A | 1 |
| Toktay, E | 1 |
| Shang, J | 1 |
| Ma, B | 2 |
| Zhu, G | 2 |
| Dong, P | 2 |
| Wang, C | 1 |
| Gu, X | 2 |
| Zi, Y | 2 |
| Li, M | 1 |
| Histing, T | 1 |
| Anton, C | 1 |
| Scheuer, C | 1 |
| Garcia, P | 1 |
| Holstein, JH | 1 |
| Klein, M | 1 |
| Matthys, R | 1 |
| Pohlemann, T | 1 |
| Menger, MD | 1 |
4 other studies available for melatonin and Femoral Fractures
| Article | Year |
|---|---|
Do peripheral melatonin agonists improve bone fracture healing? The effects of agomelatine and ramelteon on experimental bone fracture.
Topics: Acetamides; Animals; Femoral Fractures; Fracture Healing; Fractures, Bone; Indenes; Male; Melatonin; | 2020 |
Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats.
Topics: Animals; Cation Transport Proteins; Cell Differentiation; Femoral Fractures; Male; Melatonin; Mesenc | 2020 |
Melatonin Induces Osteoblastic Differentiation of Mesenchymal Stem Cells and Promotes Fracture Healing in a Rat Model of Femoral Fracture via Neuropeptide Y/Neuropeptide Y Receptor Y1 Signaling.
Topics: Alkaline Phosphatase; Animals; Arginine; Cell Differentiation; Collagen Type I; Collagen Type I, alp | 2018 |
Melatonin impairs fracture healing by suppressing RANKL-mediated bone remodeling.
Topics: Animals; Biomechanical Phenomena; Bone Remodeling; Bone Resorption; Collagen Type I; Dose-Response R | 2012 |